CN110841114B - Carbon fiber composite material artificial bone and preparation method thereof - Google Patents
Carbon fiber composite material artificial bone and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/08—Carbon ; Graphite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Abstract
The invention provides a carbon fiber composite artificial bone and a preparation method thereof, wherein the section of the artificial bone perpendicular to the length direction is U-shaped, and the artificial bone is formed by overlapping a continuous carbon fiber braided fabric composite material layer and a carbon fiber non-woven fabric composite material layer; and carbon matrixes are filled between the carbon fibers of the continuous carbon fiber braided fabric composite material layer and the carbon fiber non-woven fabric composite material layer. The composite material has the characteristics of light weight, good biocompatibility, good chemical stability, mechanical property similar to human bone, good fatigue, strong designability, no artifact and the like, and hydroxyapatite is stably adhered to surface pores and surfaces of the composite material, so that the biological activity of the composite material is improved, the bone growth is promoted and the bone proliferation is induced.
Description
Technical Field
The invention relates to an artificial bone material, in particular to a carbon fiber reinforced carbon composite artificial bone and a preparation method thereof, belonging to the field of biomedical materials.
Background
The traditional artificial bone is mainly made of metal materials, and has many clinical application problems, such as osteoporosis, fracture, rejection reaction and other postoperative complications caused by stress shielding due to mismatch of mechanical properties, toxicity of corrosion-dissolved ions, metal artifacts which are not favorable for postoperative diagnosis, necessary secondary operations and the like. The nonmetallization of bone-knitting materials has become a trend, and carbon materials have good biocompatibility. Wherein the carbon fiber, pyrolytic carbon, carbon nanotube and its compound are applied in biomedical fields. The carbon fiber composite material is a carbon-based material which is composed of carbon fibers and fabrics thereof as reinforcements, has the characteristics of light weight, strong designability, no artifact and the like compared with other materials, and has certain improvement on biocompatibility, chemical stability and mechanical property. However, the carbon fiber reinforced carbon composite bone-knitting material designed in the prior art has some obvious technical problems: for example, in the carbon-ceramic composite bone fracture plate disclosed in chinese patent (CN108171798A), the chopped carbon fibers are distributed in the structural frame in an evenly distributed or unevenly distributed manner, and the surface of the bone fracture plate is coated with resin carbon, so that the mechanical properties of the bone fracture plate are poor. Chinese patent (CN 108577957 a) discloses a carbon/carbon-silicon carbide composite bone plate, which comprises a carbon/carbon composite base material formed by sequentially and alternately laminating 0-degree non-woven fabric, a carbon fiber mesh blank and 90-degree non-woven fabric, wherein the cloth mesh lamination has large damage to continuous fibers by needling. In addition, the connection strength between the hydroxyapatite on the surface layer of the carbon fiber reinforced carbon composite material bone-knitting material in the prior art and a matrix is weak, and the bone-knitting material is easy to crack or delaminate due to large difference of thermal expansion coefficients in direct contact.
Disclosure of Invention
Aiming at the defects in the prior art, the first purpose of the invention is to provide the carbon fiber composite material artificial bone taking carbon fibers and carbon fiber fabrics as reinforcing phases, which has the characteristics of light weight, good biocompatibility, good chemical stability, mechanical property similar to human bone, good fatigue, strong designability, no artifact and the like, and hydroxyapatite is stably adhered to surface pores and surfaces, so that the biological activity of the composite material can be improved, the bone growth can be promoted, and the bone proliferation can be induced.
The invention also aims to provide a method for preparing the carbon fiber composite material artificial bone, which has simple steps and easily obtained raw materials.
In order to achieve the technical purpose, the invention provides an artificial bone made of a carbon fiber composite material, wherein the section of the artificial bone perpendicular to the length direction is U-shaped, and the artificial bone is formed by riveting and superposing a continuous carbon fiber braided fabric composite material layer and a carbon fiber non-woven fabric composite material layer; and carbon matrixes are filled between the carbon fibers of the continuous carbon fiber braided fabric composite material layer and the carbon fiber non-woven fabric composite material layer.
The continuous carbon fiber braided fabric in the carbon fiber composite material is composed of long carbon fibers, the carbon fiber content is high, the strength support is mainly provided, the carbon fiber non-woven fabric is composed of short fibers, the short fibers are arranged on the surface layer, the characteristic of high porosity of the carbon fiber non-woven fabric is utilized, a large number of surfaces can be provided for attaching hydroxyapatite, meanwhile, the short fibers penetrate into the continuous carbon fiber braided fabric to play a riveting role, the hydroxyapatite can penetrate into the carbon fibers, tissue cells can grow into the interior, and the binding capacity with tissues is improved.
The cross section of the artificial bone made of the carbon fiber composite material, which is vertical to the length direction, is in a U shape, so that the artificial bone can be conveniently butted with an autologous bone, dislocation is avoided, the connection strength is improved, and the rigidity of the artificial bone structure can be improved.
Preferably, the continuous carbon fiber braid composite material layer comprises a cloth, tape or strip woven from carbon fiber bundles.
Preferably, the carbon fiber non-woven fabric composite material layer comprises an areal density of 10g/m2～60g/m2A carbon fiber nonwoven fabric.
Preferably, the twist of the carbon fiber bundle is 10 to 500 twists/m, and the single carbon fiber bundle includes 1k, 3k, 6k, 12k or 24k carbon fibers (1k represents 1 thousand carbon fibers). The carbon fiber bundles are twisted and then woven into a continuous woven structure such as cloth, a belt or a strip, so that the rigidity can be greatly improved, and the flexural modulus can be improved.
In a preferable scheme, hydroxyapatite is adhered to the inner and surface of the pores of the carbon fiber composite material artificial bone. The hydroxyapatite is introduced to guide the growth of tissue cells and improve the binding capacity of biocompatibility and tissues.
In a more preferable scheme, the mass of the hydroxyapatite accounts for 5% -15% of the mass of the carbon fiber composite material artificial bone.
In the preferred proposal, the continuous carbon fiber braided fabric composite material layer and the carbon fiber non-woven fabric composite material layer are riveted by adopting carbon fibers in a needling way,the surface density of the riveting point is 5 points/cm225 dots/cm2. The bonding strength between the carbon fiber knitted fabric and the carbon fiber cloth and between the carbon fiber woven fabric and the carbon fiber non-woven fabric can be improved by adopting proper riveting point surface density.
Preferably, the carbon fiber composite artificial bone comprises one or two carbon fiber non-woven fabric composite material layers, and when the carbon fiber composite artificial bone comprises the two carbon fiber non-woven fabric composite material layers, the continuous carbon fiber braided fabric composite material layer is arranged between the two carbon fiber non-woven fabric composite material layers. The carbon fiber composite artificial bone has a double-layer structure or a sandwich structure.
The riveting of the invention is that the continuous carbon fiber braided fabric composite material layer and the carbon fiber non-woven fabric composite material layer are riveted and formed by carbon fibers through needling.
The invention also discloses a preparation method of the carbon fiber composite material artificial bone, which comprises the following steps:
1) twisting the carbon fiber bundles into carbon fiber ropes, then weaving into continuous carbon fiber braided fabrics, riveting carbon fiber non-woven fabrics on the surfaces of the continuous carbon fiber braided fabrics, and then preparing into a U-shaped carbon fiber prefabricated body by adopting a mold for assistance;
2) the carbon fiber preform is subjected to chemical vapor infiltration and/or impregnation-pyrolysis to generate a carbon matrix, a blank is obtained, and the blank is machined to obtain the carbon fiber preform; or generating hydroxyapatite in the pores and on the surface of the blank, and then machining to obtain the material.
Preferably, the hydroxyapatite is formed by plasma spraying, electrochemical deposition or sol-gel method.
In the preparation method, the blank body can be subjected to a high-temperature impurity removal or thermal refining treatment step or is not subjected to treatment.
The carbon fiber bundle of the present invention is twisted into one or more bundles.
The surface density of the carbon fiber nonwoven fabric of the present invention was 10g/m2～60g/m2。
The riveting of the invention adopts the carbon fiber to be processed by needlingRiveting with the surface density of the riveting point of 5 points/cm225 dots/cm2。
The mold can be a carbon material mold, the shape of which can be designed according to the needs, for example, the mold with the U-shaped cavity can be designed according to the needs.
The machining of the invention includes trimming, polishing, punching and the like.
The chemical vapor infiltration process of the invention comprises the following steps: and (2) putting the carbon fiber preform into a vacuum furnace, cracking an introduced gas source (natural gas, methane or propylene and the like are used as a carbon source, nitrogen or hydrogen is used as a diluent gas, and the flow ratio of the carbon source gas to the diluent gas is 1: 0-2) at the temperature of 850-1300 ℃, then, permeating a chemical vapor into the carbon fiber blank, and preparing the carbon fiber composite blank after 10-100 hours.
The liquid impregnation-cracking densification process comprises the following steps: the carbon fiber preform is subjected to densification processes such as resin (furan, phenolic aldehyde, copper foil and the like) or asphalt (graphite asphalt, coal asphalt) vacuum pressurization impregnation, curing treatment (resin), cracking (resin: 900-1050 ℃, normal pressure; asphalt: 750-850 ℃, 50-200 MPa) and the like. The dipping pressure is 1.0MPa to 5.0MPa, and the dipping time is 2 hours to 10 hours; the curing temperature is 160-230 ℃, and the curing time is 10-50 hours; the cracking time is 2-20 hours.
The blank can also be subjected to high-temperature impurity removal treatment, and the treatment process conditions are as follows: the temperature is 1500-2300 ℃, and the holding time is 1-10 hours.
The preparation process of the hydroxyapatite coating comprises the following steps:
(1) plasma spraying method:
1) the granularity of the hydroxyapatite powder is 20-150 mu m; 2) the plasma spraying power is 20 kW-40 kW; 3) the heat treatment temperature is 600-800 ℃, and the time is 1-5 hours.
(2) Electrochemical deposition:
1) the ratio of Ca ions to P ions in the phosphorus-containing and calcium-containing solution is 1.67; 2) the current density is 0.5mA/cm 2-3 mA/cm 2; 3) the deposition time is 20min to 150 min; 4) the temperature of the electrolyte is 25-90 ℃; 5) the heat treatment temperature is 700-1000 ℃ and the time is 1-5 hours.
(3) Sol-gel method:
1) the sol is prepared by mixing and reacting phosphoric acid triethanol and calcium nitrate, wherein the ratio of Ca ions to P ions is 1.67; 2) the gel temperature is 80-120 ℃, and the time is 3-20 hours; 3) the heat treatment temperature is 400-800 ℃, and the time is 1-5 hours.
The carbon fiber composite material artificial bone provided by the invention takes carbon as a base material, takes a continuous fiber braided fabric and a carbon fiber non-woven fabric as reinforcing phases, the two layers form an integral structure through riveting, and fibers in the carbon fiber non-woven fabric penetrate into the continuous fiber braided fabric to form a porous layer, so that hydroxyapatite with biological activity is filled into the gap layer, the falling of matrix particles can be avoided, and meanwhile, the bone growth and the induced bone proliferation are promoted.
The carbon fiber continuous fiber braided fabric can adopt single-bundle carbon fibers or multiple-bundle carbon fibers twisted into ropes and then braided strips, cloth or belts and the like.
Compared with the prior art, the technical scheme of the invention has the beneficial technical effects that:
the artificial bone of the invention adopts the carbon fiber composite material, has the characteristics of light weight, good biocompatibility, good chemical stability, mechanical property similar to that of human bone, good fatigue property, strong designability, no artifact and the like, and hydroxyapatite is stably adhered to surface pores and surfaces, thus improving the bioactivity of the composite material, promoting bone growth and inducing bone proliferation.
The artificial bone made of the carbon fiber composite material has a laminated structure of the continuous carbon fiber braided fabric and the carbon fiber non-woven fabric, the continuous carbon fiber is mainly composed of long fibers, the carbon fiber content is high, the strength support is mainly provided, the carbon fiber non-woven fabric is composed of short fibers, the carbon fiber non-woven fabric is arranged on the surface layer, a large number of surfaces can be provided for attaching hydroxyapatite by utilizing the characteristic of high porosity of the carbon fiber non-woven fabric, meanwhile, the short fibers penetrate into the continuous carbon fiber braided fabric to play a riveting role, the penetration of the hydroxyapatite into the carbon fiber and the growth of tissue cells to the inside are facilitated, and the binding capacity with tissues is improved.
The carbon fiber composite material artificial bone has good mechanical properties: the tensile strength is 120 MPa-220 MPa, the tensile modulus is 10 GPa-30 GPa, and the bending strength is more than or equal to 180 MPa.
Drawings
Fig. 1 is a structural view of a twisted continuous carbon fiber braid.
FIG. 2 is an SEM photograph of a two-layer structure carbon fiber composite prepared in example 1; wherein (a) is a cross-section; (b) is a surface; (a) the upper layer is non-woven fabric (short fiber layer), and the lower layer is twisted carbon fiber continuous braided strips, and has a two-layer structure.
Fig. 3 is a schematic view of the shape of the artificial bone made of the carbon fiber composite material, the left view is a top view, and the right side is a schematic view of a section in the length direction.
Detailed Description
The following examples are intended to further illustrate the present disclosure, but not to limit the scope of the claims.
Example 1
1) Twisting 2 bundles of 6k carbon fibers into a carbon fiber rope with the twist of 200 twists/m; then weaving the 12 twisted carbon fiber ropes into strip-shaped continuous carbon fiber braided fabrics.
2) The surface density is 20g/m by using a needle2The carbon fiber non-woven fabric is riveted on the continuous carbon fiber braided fabric, and the density of the riveting point is 10 points/cm2And (5) carrying out auxiliary forming by adopting a mould to obtain the U-shaped carbon fiber preform.
3) Densifying the carbon fiber preform by a dipping-cracking method to obtain a blank; the densification process comprises the following steps: the carbon fiber manufactured body is subjected to densification processes such as coal pitch vacuum pressurization impregnation, cracking and the like; the dipping pressure is 2.0MPa, and the dipping time is 8 hours; the cracking temperature is 800 ℃, the pressure is 80MPa, and the time is 4 hours.
4) And (3) putting the blank in the step (3) into a high-temperature furnace, heating to 2000 ℃ under the condition of vacuum or protective atmosphere, keeping the temperature for 2 hours, and removing impurities.
5) Adopting plasma spraying to generate hydroxyapatite on the blank treated by the step 4), wherein the hydroxyapatite permeates into the pores and forms a bioactive layer on the surface, and the process conditions are as follows: the powder granularity is 75 μm, and the plasma spraying power is 35 kW; the heat treatment temperature is 750 ℃, and the time is 2 hours; the mass of the hydroxyapatite accounts for 12 percent.
6) And (3) punching, wherein the aperture is phi 2mm, and the interval is 15mm, and the artificial bone is mainly used for fixation, so that the carbon fiber composite material artificial bone is obtained.
The tensile strength of the artificial bone made of the carbon fiber composite material is 150MPa, the tensile modulus is 18GPa, the bending strength is 220MPa, the surface of the artificial bone is provided with pores, and hydroxyapatite is uniformly adhered to the surface and permeates into the pores.
Example 2
1) Firstly twisting 4 bundles of 1k carbon fibers into a carbon fiber rope, wherein the twist is 300 twists/m; then weaving the 12 twisted carbon fiber ropes into strip-shaped continuous fiber braided fabric.
2) The surface density is 30g/m by using a needle2The carbon fiber non-woven fabric is riveted on two sides of the continuous fiber braided fabric to form a sandwich structure, and the density of the riveting points is 10 points/cm2And (5) carrying out auxiliary forming by adopting a mould to obtain the U-shaped carbon fiber preform.
3) Carrying out matrix carbon densification on the carbon fiber preform through chemical vapor infiltration to obtain a blank; the densification process comprises the following steps: at the temperature of 900 ℃, introducing propylene gas (nitrogen is used as diluent gas, the flow ratio of the propylene to the nitrogen is 1:0.5), cracking, and then permeating chemical vapor into the carbon fiber blank for 60 hours.
4) Generating hydroxyapatite on the blank treated in the step 3) by adopting plasma spraying, wherein the hydroxyapatite permeates into the pores and forms a bioactive layer on the surface; the process conditions for spraying the hydroxyapatite comprise: the powder granularity is 85 μm, and the plasma spraying power is 30 kW; the heat treatment temperature is 700 ℃, and the time is 2 hours; the mass of the hydroxyapatite accounts for 8 percent.
6) And (3) punching, wherein the aperture is phi 2mm, and the interval is 15mm, and the artificial bone is mainly used for fixation, so that the carbon fiber composite material artificial bone is obtained.
The tensile strength of the artificial bone made of the carbon fiber composite material is 125MPa, the tensile modulus is 12GPa, the bending strength is 190MPa, the surface of the artificial bone is provided with pores, and hydroxyapatite is uniformly adhered to the surface and permeates into the pores.
Example 3
1) Twisting 3 bundles of 12k carbon fibers into a carbon fiber rope with the twist of 300 twists/m; then weaving the 6 twisted carbon fiber ropes into strip-shaped continuous fiber braided fabric.
2) The surface density is 30g/m by using a needle2The carbon fiber non-woven fabric is riveted on the continuous fiber braided fabric, and the density of the riveting points is 10 points/cm2And (5) carrying out auxiliary forming by adopting a mould to obtain the U-shaped carbon fiber preform.
3) Densifying the carbon fiber preform by a dipping-cracking method to obtain a blank; the densification process comprises the following steps: the carbon fiber manufactured body is subjected to densification processes such as coal pitch vacuum pressurization impregnation cracking and the like; the dipping pressure is 3.0MPa, and the dipping time is 10 hours; the cracking temperature is 900 ℃, the pressure is 80MPa, and the time is 5 hours.
4) And (3) putting the blank in the step (3) into a high-temperature furnace, heating to 2000 ℃ under the condition of vacuum or protective atmosphere, keeping the temperature for 2 hours, and removing impurities.
5) And (3) punching, wherein the aperture is phi 2mm, and the interval is 15mm, and the artificial bone is mainly used for fixation, so that the carbon fiber composite material artificial bone is obtained.
The tensile strength of the artificial bone made of the carbon fiber composite material is 160MPa, the tensile modulus is 19GPa, the bending strength is 230MPa, and the surface of the artificial bone has obvious pores.
COMPARATIVE EXAMPLE 1 (without provision of carbon fiber nonwoven layer)
1) Twisting 2 bundles of 6k carbon fibers into a carbon fiber rope with the twist of 200 twists/m; and then weaving the 12 twisted carbon fiber ropes into strip-shaped continuous fiber braided fabrics, and performing auxiliary molding by adopting a mold to obtain the U-shaped carbon fiber preform.
2) Densifying the carbon fiber preform by a dipping-cracking method to obtain a blank; the densification process comprises the following steps: the carbon fiber manufactured body is subjected to densification processes such as coal pitch vacuum pressurization impregnation, cracking and the like; the dipping pressure is 2.0MPa, and the dipping time is 8 hours; the cracking temperature is 800 ℃, the pressure is 80MPa, and the time is 4 hours.
3) Putting the blank in the step 2) into a high-temperature furnace, heating to 2000 ℃ under the condition of vacuum or protective atmosphere, keeping the temperature for 2 hours, and removing impurities.
4) Generating hydroxyapatite on the blank treated in the step 3) by adopting plasma spraying, wherein the hydroxyapatite permeates into the pores and forms a bioactive layer on the surface; the process conditions for spraying the hydroxyapatite comprise: the powder granularity is 75 μm, and the plasma spraying power is 35 kW; the heat treatment temperature is 750 ℃, and the time is 2 hours; the mass of the hydroxyapatite accounts for 12 percent.
5) And (3) punching, wherein the aperture is phi 2mm, and the interval is 15mm, and the artificial bone is mainly used for fixation, so that the carbon fiber composite material artificial bone is obtained.
The tensile strength of the artificial bone made of the carbon fiber composite material is 164MPa, the tensile modulus is 5GPa, and the bending strength is 80MPa, compared with the example 1, although the tensile strength is improved, the tensile modulus and the bending strength are obviously reduced, no obvious pores are formed on the surface of the artificial bone, and the hydroxyapatite is not uniformly adhered.
COMPARATIVE EXAMPLE 2 (not made into U-shaped Structure)
1) Twisting 2 bundles of 6k carbon fibers into a carbon fiber rope with the twist of 200 twists/m; then weaving the 12 twisted carbon fiber ropes into strip-shaped continuous fiber braided fabric.
2) The surface density is 20g/m by using a needle2The carbon fiber non-woven fabric is riveted on the continuous fiber braided fabric, and the density of the riveting points is 10 points/cm2And obtaining the carbon fiber preform.
3) Densifying the carbon fiber preform by a dipping-cracking method to obtain a blank; the densification process comprises the following steps: the carbon fiber manufactured body is subjected to densification processes such as coal pitch vacuum pressurization impregnation, curing treatment, cracking and the like; the dipping pressure is 2.0MPa, and the dipping time is 8 hours; the cracking temperature is 800 ℃, the pressure is 80MPa, and the time is 4 hours.
4) And (3) putting the blank in the step (3) into a high-temperature furnace, heating to 2000 ℃ under the condition of vacuum or protective atmosphere, keeping the temperature for 2 hours, and removing impurities.
5) Generating hydroxyapatite on the blank treated in the step 4) by adopting plasma spraying, wherein the hydroxyapatite permeates into the pores and forms a bioactive layer on the surface; the process conditions for spraying the hydroxyapatite comprise: the powder granularity is 75 μm, and the plasma spraying power is 35 kW; the heat treatment temperature is 750 ℃, and the time is 2 hours; the mass of the hydroxyapatite accounts for 12 percent.
6) And (3) punching, wherein the aperture is phi 2mm, and the interval is 15mm, and the artificial bone is mainly used for fixation, so that the carbon fiber composite material artificial bone is obtained.
The carbon fiber composite material has the tensile strength of 150MPa, the tensile modulus of 8GPa and the bending strength of 100MPa, and the surface of the artificial bone is provided with pores, and hydroxyapatite is uniformly adhered to the surface and permeates into the pores.
Claims (4)
1. The utility model provides a carbon-fibre composite artificial bone which characterized in that: the cross section of the artificial bone perpendicular to the length direction is U-shaped, the artificial bone is formed by overlapping a continuous carbon fiber braided fabric composite material layer and a carbon fiber non-woven fabric composite material layer, the continuous carbon fiber braided fabric composite material layer and the carbon fiber non-woven fabric composite material layer are riveted by adopting carbon fibers in a needling mode, and the areal density of a riveting point is 5 points/cm225 dots/cm2(ii) a Carbon matrixes are filled between the carbon fibers of the continuous carbon fiber braided fabric composite material layer and the carbon fiber non-woven fabric composite material layer;
hydroxyapatite is adhered to the inner and surface of the pores of the artificial bone made of the carbon fiber composite material;
the carbon fiber composite artificial bone comprises one or two carbon fiber non-woven fabric composite material layers, and when the carbon fiber composite artificial bone comprises two carbon fiber non-woven fabric composite material layers, the continuous carbon fiber braided fabric composite material layer is arranged between the two carbon fiber non-woven fabric composite material layers; the carbon fiber non-woven fabric composite material layer comprises the following components with the surface density of 10g/m2~60g/m2A carbon fiber nonwoven fabric;
the continuous carbon fiber woven fabric composite material layer comprises a cloth, tape or strip woven from carbon fiber bundles; the twist of the carbon fiber bundle is 10-500 twists/m, and the single carbon fiber bundle comprises 1k, 3k, 6k, 12k or 24k carbon fibers.
2. The artificial bone made of carbon fiber composite material according to claim 1, wherein: the mass of the hydroxyapatite accounts for 5-15% of the mass of the carbon fiber composite material artificial bone.
3. The method for preparing the artificial bone made of the carbon fiber composite material according to any one of claims 1 to 2, which is characterized in that: the method comprises the following steps:
1) twisting the carbon fiber bundles into carbon fiber ropes, then weaving into a continuous fiber braided fabric, riveting carbon fiber non-woven fabric on the surface of the continuous fiber braided fabric in a needling manner, and then preparing a U-shaped carbon fiber preform by adopting a mold;
2) the carbon fiber preform is subjected to chemical vapor infiltration and/or impregnation-pyrolysis to generate a carbon matrix, a blank is obtained, and the blank is machined to obtain the carbon fiber preform;
or generating hydroxyapatite in the pores and on the surface of the blank, and then machining to obtain the material.
4. The method for preparing the artificial bone made of the carbon fiber composite material according to the claim 3, which is characterized in that: hydroxyapatite is produced by plasma spraying, electrochemical deposition or sol-gel methods.
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| CN110585491B (en) * | 2019-09-27 | 2021-12-14 | 长沙晟天新材料有限公司 | Carbon fiber composite bone fracture plate and preparation method thereof |
| CN111265713B (en) * | 2020-03-22 | 2021-12-28 | 西北工业大学 | Preparation method of strong-binding-force biological coating on surface of carbon/carbon composite material |
| CN111603612B (en) * | 2020-04-10 | 2022-05-13 | 西北工业大学 | Multilayer alternating structure composite bone repair material and preparation method thereof |
| CN112190756B (en) * | 2020-09-28 | 2022-04-22 | 湖南碳康生物科技有限公司 | Preparation method of carbon fiber composite material profiling artificial bone |
| CN112206355B (en) * | 2020-09-28 | 2023-03-17 | 湖南碳康生物科技有限公司 | Profiling artificial bone and preparation method thereof |
| CN113831147A (en) * | 2021-10-09 | 2021-12-24 | 上海世碳复合材料科技有限公司 | Carbon-carbon composite material artificial skeleton |
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