CN1107844A - 二氢化茚衍生物和其制法及合成该衍生物的中间体 - Google Patents
二氢化茚衍生物和其制法及合成该衍生物的中间体 Download PDFInfo
- Publication number
- CN1107844A CN1107844A CN94113330A CN94113330A CN1107844A CN 1107844 A CN1107844 A CN 1107844A CN 94113330 A CN94113330 A CN 94113330A CN 94113330 A CN94113330 A CN 94113330A CN 1107844 A CN1107844 A CN 1107844A
- Authority
- CN
- China
- Prior art keywords
- indane
- compound
- pyridazine
- ketone
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP335250/93 | 1993-12-28 | ||
| JP33525093 | 1993-12-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1107844A true CN1107844A (zh) | 1995-09-06 |
Family
ID=18286423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN94113330A Pending CN1107844A (zh) | 1993-12-28 | 1994-12-28 | 二氢化茚衍生物和其制法及合成该衍生物的中间体 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5686452A (enExample) |
| EP (1) | EP0661273B1 (enExample) |
| KR (1) | KR950017968A (enExample) |
| CN (1) | CN1107844A (enExample) |
| AT (1) | ATE180251T1 (enExample) |
| CA (1) | CA2138812A1 (enExample) |
| DE (1) | DE69418582D1 (enExample) |
| DK (1) | DK0661273T3 (enExample) |
| MX (1) | MX9500251A (enExample) |
| SG (1) | SG48755A1 (enExample) |
| TW (1) | TW288012B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL118631A (en) * | 1995-06-27 | 2002-05-23 | Tanabe Seiyaku Co | History of pyridazinone and processes for their preparation |
| US20040151759A1 (en) * | 2002-08-16 | 2004-08-05 | Douglas Cleverly | Non-animal product containing veterinary formulations |
| EP2328586A2 (en) * | 2008-05-20 | 2011-06-08 | Cephalon, Inc. | Substituted pyridazinone derivatives as histamine-3 (h3) receptor ligands |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5179018A (en) * | 1983-10-14 | 1993-01-12 | Centocor, Inc. | Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria |
| US4816454A (en) * | 1984-09-21 | 1989-03-28 | Cassella Aktiengesellschaft | 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use |
| EP0194548A3 (de) * | 1985-03-12 | 1988-08-17 | Dr. Karl Thomae GmbH | Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE3623944A1 (de) * | 1986-07-16 | 1988-02-11 | Thomae Gmbh Dr K | Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| IL88314A (en) * | 1987-11-18 | 1994-05-30 | Tanabe Seiyaku Co | Sulphonylamino indane derivatives, their preparation and pharmaceutical compositions containing them |
| AU651182B2 (en) * | 1991-03-01 | 1994-07-14 | Zeria Pharmaceutical Co., Ltd. | Indan derivative and thromboxane antagonist containing the same |
| CA2099743A1 (en) * | 1992-07-02 | 1994-01-03 | Akihiko Ishida | Pyridazinone derivatives and processes for preparing the same |
| CA2139088A1 (en) * | 1993-12-28 | 1995-06-29 | Akihiko Ishida | Indane derivatives, processes for preparing the same and synthetic intermediate of the same |
-
1994
- 1994-12-22 CA CA002138812A patent/CA2138812A1/en not_active Abandoned
- 1994-12-27 SG SG1996001274A patent/SG48755A1/en unknown
- 1994-12-27 DE DE69418582T patent/DE69418582D1/de not_active Expired - Lifetime
- 1994-12-27 TW TW083112220A patent/TW288012B/zh active
- 1994-12-27 AT AT94120687T patent/ATE180251T1/de not_active IP Right Cessation
- 1994-12-27 DK DK94120687T patent/DK0661273T3/da active
- 1994-12-27 EP EP94120687A patent/EP0661273B1/en not_active Expired - Lifetime
- 1994-12-28 KR KR1019940038059A patent/KR950017968A/ko not_active Ceased
- 1994-12-28 CN CN94113330A patent/CN1107844A/zh active Pending
-
1995
- 1995-01-02 MX MX9500251A patent/MX9500251A/es unknown
-
1996
- 1996-12-16 US US08/767,392 patent/US5686452A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ATE180251T1 (de) | 1999-06-15 |
| CA2138812A1 (en) | 1995-06-29 |
| TW288012B (enExample) | 1996-10-11 |
| DK0661273T3 (da) | 1999-11-08 |
| KR950017968A (ko) | 1995-07-22 |
| EP0661273A1 (en) | 1995-07-05 |
| DE69418582D1 (de) | 1999-06-24 |
| US5686452A (en) | 1997-11-11 |
| SG48755A1 (en) | 1998-05-18 |
| EP0661273B1 (en) | 1999-05-19 |
| MX9500251A (es) | 1997-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1419150B1 (fr) | Derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique | |
| EP1254134B1 (fr) | Derives de 1,3-dihydro-2h-indol-2-one et leur utilisation en tant que ligands pour les recepteurs v1b ou v1b et v1a de l'arginine-vasopressine | |
| EP0518731B1 (fr) | Dérivés de 2-(indol-2-yl-carbonylamino)-thiazoles,leur préparation et compositions pharmaceutiques en contenant | |
| CN1105708C (zh) | 1－苯基吡唑化合物类及其药学应用 | |
| US20030207874A1 (en) | Pyrazole derivatives and their use as gastrin and cholecystokin receptor ligands | |
| EP1259505B1 (fr) | Derives de 1,3-dihydro-2h-indol-2-one et leur utilisation en tant que ligands des recepteurs v1b ou v1b et v1a de l'arginine-vasopressine | |
| CN1237180A (zh) | 噻吩并－三唑并二氮杂䓬化合物及其医药用途 | |
| FR2804114A1 (fr) | Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant | |
| CN1418215A (zh) | 具有IKB－激酶抑制活性的取代的β－咔啉 | |
| CN1203589A (zh) | 新的化合物 | |
| CN1305465A (zh) | 芳基链烷酰基哒嗪化合物 | |
| CN1142227A (zh) | 新的噻唑烷-4-酮衍生物 | |
| FR2927625A1 (fr) | Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique | |
| EP2294068B1 (fr) | DERIVES DE 1,3-DIHYDRO-2H-PYRROLO(3,2-b) PYRIDIN-2-ONE, LEUR PREPARATION ET LEURS APPLICATIONS EN THERAPEUTIQUE | |
| WO2014075618A1 (zh) | 含有杂环的5-羟基吲哚类衍生物及其用途 | |
| JPH11513993A (ja) | プロトン・ポンプ・インヒビター | |
| EP0841330B1 (fr) | Nouveaux dérivés aminométhyl hétérocycliques, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent | |
| EP0136198B1 (fr) | Dérivés de triazolo pyrimidine, leur procédé de préparation et leur application thérapeutique en tant que toni-cardiaques | |
| TW200303205A (en) | Gastrin and cholecystokinin receptor ligands | |
| EP0383690A1 (fr) | Nouveaux dérivés de l'acide 2-amino pentanedioique, leur procédé et les intermédiaires de préparation, leur application comme médicaments et les compositons les renfermant | |
| US10519105B2 (en) | KCNQ2-5 channel activator | |
| CN1107844A (zh) | 二氢化茚衍生物和其制法及合成该衍生物的中间体 | |
| EP1525198B1 (fr) | Derives d'acyloxypyrrolidine et leur utilisation en tant que ligands des recepteurs v1b ou v1b et v1a de avp | |
| RU2178790C2 (ru) | Производные дибензо[d, g][1,3]диоксоцина и дибензо-[d,g][1,3,6]диоксазоцина, способ их получения, фармацевтическая композиция на их основе и способ лечения нейрогенного воспаления, нейропатии и ревматоидного артрита | |
| FR2944013A1 (fr) | Derives de 1-alkyl-cinnolin-4(1h)-one substitues,leur preparation et leur application en therapeutique. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C01 | Deemed withdrawal of patent application (patent law 1993) | ||
| WD01 | Invention patent application deemed withdrawn after publication |