CN110772242A - Automatic blood pressure measuring device with autonomic nerve analysis function - Google Patents
Automatic blood pressure measuring device with autonomic nerve analysis function Download PDFInfo
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- CN110772242A CN110772242A CN201811433026.XA CN201811433026A CN110772242A CN 110772242 A CN110772242 A CN 110772242A CN 201811433026 A CN201811433026 A CN 201811433026A CN 110772242 A CN110772242 A CN 110772242A
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- blood pressure
- heart rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
Abstract
The present invention relates to an automatic blood pressure measuring device with an autonomic nerve analysis function. Conventionally, when the autonomic nerve analysis function is measured simultaneously with the blood pressure measurement, it is considered to perform the measurement by separately combining an apparatus for detecting a cardiac rhythm synchronous wave such as an electrocardiographic apparatus or a pulse meter, but since the entire apparatus is complicated, it is difficult to perform simple measurement. The invention provides a blood pressure measuring device which inserts an arm into a cuff and measures blood pressure, and the device can simultaneously and simply measure the pressure measurement and the autonomic nerve analysis function by detecting the heart rhythm period correlation value from the heart rhythm synchronous wave obtained in the blood pressure measurement.
Description
Technical Field
The invention provides an automatic sphygmomanometer with an autonomic nerve analysis function, which is used for checking and displaying a blood pressure measurement result and an autonomic nerve state during blood pressure measurement based on a rhythm synchronous wave obtained from an artery during cuff compression.
Background
Fig. 8 shows patent document 1, and fig. 8 is a perspective view illustrating the entire configuration of a conventional automatic blood pressure measurement device 10A with an autonomic nerve evaluation function. This automatic blood pressure measurement device 10A requires a cuff 12A wrapped around a part of a living body, for example, an upper arm, and a plurality of ECG (electrocardiogram) electrodes 14aA and 14 bA.
Patent document 1: japanese patent No. 5584111.
Disclosure of Invention
With this prior art, it is necessary for the subject to attach an ECG electrode for acquiring an electrocardiogram to the subject while wearing the cuff on the arm, which is cumbersome, and it is also necessary to prepare an electrocardiogram detection apparatus therefor.
The present invention is to solve the problems of the conventional constitution, and is to provide: at the same time of measuring the blood pressure, it is not necessary to provide a separate electrode for obtaining the electrocardiograph, and for example, the time of the pulse interval is sampled as a correlation value of the heart rate cycle.
As a general method of autonomic nerve analysis, a method of performing frequency analysis on fluctuation of rhythm fluctuation is known. The fluctuation of the rhythm fluctuation can be obtained by measuring, for example, an electrocardiographic waveform or an R-R interval of a pulse.
a first decompression unit configured to decompress the pressure of the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of a living body is compressed using the cuff; a blood pressure determination unit configured to determine a blood pressure value of the living body based on a heart rhythm synchronization wave obtained before the blood pressure determination is completed; a second decompression unit configured to continue decompression of the pressure in the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of the living body is compressed using the cuff; a heart rate cycle correlation value detection unit that successively detects a heart rate cycle correlation value based on at least a part of the heart rate synchronous waves obtained before the completion of the blood pressure determination and the heart rate synchronous waves obtained after the completion of the blood pressure determination; a heart rate cycle correlation value frequency analyzing unit that performs frequency analysis on the fluctuation of the heart rate cycle correlation value detected by the heart rate cycle correlation value detecting unit and calculates a frequency component ratio of the low frequency component to the high frequency component; a unit for storing and outputting the calculated frequency component ratios together; and a unit that determines the degree of stress of the subject from the frequency component ratio.
a first decompression unit configured to decompress the pressure of the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of a living body is compressed using the cuff;
a blood pressure determination unit configured to determine a blood pressure value of the living body based on a heart rhythm synchronization wave obtained before the blood pressure determination is completed;
a second decompression unit configured to continue decompression of the pressure in the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of the living body is compressed using the cuff;
a stress level determination unit that determines a stress level of the living body based on the heart rate synchronous wave;
and a blood pressure determining unit which determines the blood pressure value as a final blood pressure value when the tension is in a preset reference range.
a heart rate cycle correlation value detection unit that successively detects a heart rate cycle correlation value based on at least a part of the heart rate synchronous waves obtained before the completion of the blood pressure determination and the heart rate synchronous waves obtained after the completion of the blood pressure determination;
a heart rate cycle correlation value frequency analyzing unit that performs frequency analysis on the fluctuation of the heart rate cycle correlation value detected by the heart rate cycle correlation value detecting unit and calculates a frequency component ratio of the low frequency component to the high frequency component; and
a unit that determines the degree of stress of the subject from the frequency component ratio.
and a unit for storing and outputting the calculated frequency component ratio.
means for performing a re-measurement or a warning of an abnormality in blood pressure when the degree of tension at the time of the determination of the subject exceeds a predetermined reference value.
An aspect 7 of the present invention provides an automatic blood pressure measurement device for measuring a blood pressure value of a living body based on a heart rhythm synchronous wave obtained from an artery when a part of the living body is compressed using a cuff, the automatic blood pressure measurement device including: a pressure reducing unit that reduces the pressure of the cuff until the blood pressure determination at the time of measurement is completed; a heart rate cycle correlation value detection unit which is provided with two decompression units after the measurement is finished and is used for successively detecting a heart rate cycle correlation value according to the heart rate synchronous wave obtained in the blood pressure measurement; a heart rate cycle correlation value frequency analyzing unit that performs frequency analysis on the fluctuation of the heart rate cycle correlation value detected by the heart rate cycle correlation value detecting unit and calculates a frequency component ratio of the low frequency component to the high frequency component; a unit for storing and outputting the calculated frequency component ratios together; and a unit that determines the degree of stress of the subject from the frequency component ratio.
As described above, the automatic blood pressure monitor with an autonomic nerve analysis function according to the present invention can simultaneously perform blood pressure measurement and frequency analysis of a value related to a cardiac cycle indicating the state of an autonomic nerve with one measurement device.
Also, the following features are provided: the usual blood pressure value can be estimated from the past blood pressure value and the history data of the tension of the present invention.
Drawings
FIG. 1 is a perspective view of an automatic blood pressure monitor with autonomic nerve analysis of the present invention;
FIG. 2 is a block diagram of an automatic blood pressure monitor with autonomic nerve analysis of the present invention;
FIG. 3 is a diagram of the pulse rate and the pulse peak position of the automatic sphygmomanometer with autonomic nerve analysis function according to the present invention;
FIG. 4 is a graph of the pulse interval of the automatic sphygmomanometer with autonomic nerve analysis function according to the present invention;
FIG. 5 is a transition diagram of the pulse intervals of the automatic blood pressure monitor with autonomic nerve analysis of the present invention at equal time intervals;
FIG. 6 is an autonomic nerve analysis result display screen of the automatic blood pressure monitor with autonomic nerve analysis function of the present invention;
fig. 7 is a flowchart showing the contents of an example of a program stored in a CPU of the automatic blood pressure monitor with an autonomic nerve analysis function of the present invention;
fig. 8 shows a conventional example.
Detailed Description
Fig. 1 is a perspective view showing an automatic blood pressure monitor with an autonomic nerve analysis function according to the present invention.
In fig. 1, reference numeral 1 denotes an automatic blood pressure monitor device main body with an autonomic nerve analysis function according to the present invention, 2 denotes an arm insertion portion into which an arm 3 is inserted, and 4 denotes an arm rest on which an arm is placed. Fig. 5 shows the cuff which grips the arm and blocks blood during blood pressure measurement. The palm is shown at 6.
A display unit 7 shows a blood pressure measurement result, an autonomic nerve analysis result, and the like, and the surface is a touch panel 71 and performs various input processes. Fig. 8 shows a printer which prints the result thereof.
Fig. 2 is an internal block diagram of the automatic blood pressure monitor with autonomic nerve analysis function of the present invention. Reference numeral 9 denotes an air supply pump for supplying air to the cuff 5, and the air inside the cuff 5 is adjusted by an air discharge valve 10 for discharge during measurement.
The arm 3 of the subject is inserted into the cuff 5, the ID (Identification) of the subject is input on the touch panel 71, and the measurement is started by a measurement button (not shown).
The geared motor 111 is driven to clamp the cuff 5 to the arm 3 of the subject, and the brake electromagnet 112 is energized to fix the cuff 5 to the arm of the subject.
Air is supplied from the air supply pump 9 to the cuff 5, and the inserted arm 3 is clamped until a predetermined pressure is reached. The pressure detection circuit 12 includes a semiconductor pressure sensor and an electric circuit. At the time of measurement, an electrical output proportional to the pressure value of the cuff 5 is obtained, and the amount of change in the pulse wave is superimposed on the electrical output.
The pulse detection circuit 13 performs filtering processing on the electrical output and outputs only the amount of change in the pulse. Fig. 14 shows a microcomputer connected to the air supply pump 9, the exhaust valve 10, the pressure detection circuit 12, and the pulse detection circuit 13, the microcomputer including a CPU (Central Processing Unit) 141, and the CPU141 controls the operations of the elements included in the automatic sphygmomanometer with an autonomic nerve analysis function according to the present invention by a program of a flowchart of fig. 7 described later. The external memory 15 stores measurement result data as time-series data for each subject.
Fig. 3 is a graph showing pulse data sampled and processed by the pulse detection circuit. The extraction is performed by a band pass filter (0.7Hz to 3.0Hz) of the pulse band. Thereafter, the position and value of the peak of each pulse are obtained and plotted as fig. 3.
Fig. 4 is a graph in which the peak interval of the pulse wave is plotted on the vertical axis and the occurrence time point of the pulse wave is plotted on the horizontal axis, and the fluctuation of the peak interval of the pulse wave is plotted.
Fig. 5 is a diagram in which the peak interval based on the generated pulse described above is replaced with equal interval data (500msec ) (lagrange interpolation processing).
Fig. 6 is a display screen showing the result of autonomic nerve analysis of the automatic blood pressure monitor with autonomic nerve analysis function of the present invention. The power spectral density is frequency analyzed for the fluctuations in the heart rhythm and the power spectral intensity is plotted. In the case of this figure, the area of power of 0.04 to 0.15Hz is the low-frequency component of the frequency analysis of the fluctuation of the peak interval of the pulse, and the area of power of 0.15 to 0.40Hz is the high-frequency component of the frequency analysis. As for the analysis result, LF (low frequency component) and HF (high frequency component) are components numerically expressing the result of the frequency analysis, and LF/HF is a component ratio of the low frequency component to the high frequency component.
Fig. 7 is a flowchart showing the contents of software used in the automatic blood pressure monitor with an autonomic nerve analysis function of the present invention.
When the subject matching the ID is selected in S1 and measurement is started, the initial inflation value for inflating the cuff 5 of fig. 1 wrapped around the arm of the subject is set to 190mmHg in S2.
Air supply is started from the air supply port of the cuff 5 as shown in S3, and air supply is stopped when the pressure value in the cuff 5 reaches 190mmHg as shown in S4 and S5.
The rhythm synchronization wave, such as fluctuation of heart rate fluctuation, can be obtained by measuring the R-R interval of the electrocardiographic waveform or pulse.
The data on the pressure in the cuff 5 and the pulse data are continuously taken into the memory of the microcomputer 14 at a constant cycle as shown in S7 by the first decompression means, and when the air supply is stopped as shown in S5, the decompression rate is calculated as shown in S6, and the pressure in the cuff 5 is gradually decompressed at a constant rate by the operation of the exhaust valve 10. A blood pressure determination unit determines a blood pressure by an oscillometric method based on the acquired pressure data and the acquired pulse data.
The acquisition of pulse data is continued until a predetermined time, here 30 seconds, has elapsed from the time of the determination of the highest blood pressure as shown in S11 by the second decompression means, and the second decompression means reduces the load on the subject within a range in which the value related to the cardiac cycle can be detected for autonomic nerve analysis after the blood pressure value is normally determined by the blood pressure determination means as shown in S8, so that the pressure can be intermittently decompressed and fixed.
As shown in S9 to S10, since the detected pulse wave level gradually decreases as the pressure reduction progresses, the exhaust valve is closed and the pressure reduction is stopped at the time point when the detected pulse wave level becomes 1/2 or less of the maximum pulse wave level.
As shown in S11 to S12, pulse data is acquired after a predetermined time, here 30 seconds, has elapsed from the time of the determination of the highest blood pressure, and then the exhaust valve is opened to proceed to the autonomic nerve analysis processing.
In one embodiment of the present invention, the sampling process is performed, for example, with the time of the pulse interval as the correlation value of the heart rate cycle.
As shown in S13, the autonomic nerve analysis data processing detects the respective peak positions of the sampled pulses and calculates peak position data. The R-R interval between the respective pulse waves is compared with the average R-R of the entire pulse waves, and when the R-R interval is equal to or higher than a predetermined level or equal to or lower than the predetermined level, the R-R interval is replaced with the average R-R and corrected.
As shown in S14, the peak position data is converted into the equal time interval data, and the time between peaks of the pulse is calculated and converted into the time interval data. The pulse peak interval value at each peak position can be obtained from the peak position data, but time series data (data of a certain period) is necessary for frequency analysis. Therefore, it is necessary to use the pulse peak interval value (actual data) at each peak position obtained from the peak position data and interpolate data at a time point when the actual data does not exist. The interpolation is performed by using lagrange interpolation.
In an embodiment of the invention, the above process is performed by a heart rate cycle related value detecting unit, for example.
As shown in S15, fourier transform of the data (500msec, 1024 points) of the equal time intervals obtained in S14 is performed, and a power spectrum is calculated. The index value has a power spectrum area of 0.04 Hz-0.15 Hz for LF and 0.15 Hz-0.40 Hz for HF.
In an embodiment of the present invention, the above process is performed by, for example, a heart rate cycle related value frequency analysis unit.
As shown in S16, the index values LF and HF and the blood pressure values at the time points thereof are recorded in time series as data of the subject with which the ID matches.
In an embodiment of the invention, the above procedure is for example performed by a unit that stores and outputs the calculated frequency component ratio together.
In order to determine whether or not the measured blood pressure value is within the appropriate value range as shown in S17, if LF/HF obtained by frequency analysis of the fluctuation is within the reference range, the result is normally displayed if the tonus, i.e., LF/HF, is normal as shown in S18, and if the tonus is out of range, the inappropriate result is displayed as shown in S19, and the blood pressure is measured again or the abnormality is reminded.
In still another embodiment provided by the present invention, for example, when the tension determined by the tension determining unit is within a predetermined reference range, that is, when LF/HF is normal, the blood pressure determining unit determines the blood pressure value determined by the blood pressure determining unit as the final blood pressure value, and displays the result. For another example, the re-measurement means performs re-measurement when the tension determined by the tension determination means exceeds a predetermined reference value. For another example, the blood pressure abnormality reminding unit reminds of abnormality of blood pressure when the degree of tension exceeds a predetermined reference value. For example, when the tension exceeds a predetermined reference value, the blood pressure abnormality reminding means reminds of abnormality of blood pressure, and the remeasurement means performs remeasurement.
The above embodiments provided by the present invention relate to an automatic blood pressure measurement device with an autonomic nerve analysis function. Conventionally, when the autonomic nerve analysis function is measured simultaneously with the blood pressure measurement, it is considered to perform the measurement by separately combining an apparatus for detecting a cardiac rhythm synchronous wave such as an electrocardiographic apparatus or a pulse meter, but since the entire apparatus is complicated, it is difficult to perform simple measurement. The invention provides a blood pressure measuring device which inserts an arm into a cuff and measures blood pressure, and the device can simultaneously and simply measure the pressure measurement and the autonomic nerve analysis function by detecting the heart rhythm period correlation value from the heart rhythm synchronous wave obtained in the blood pressure measurement.
Description of the symbols
Automatic sphygmomanometer device body with autonomic nerve analysis function
2 arm insertion part
3 arm
4 arm placing table
5 cuff
6 palm
7 display part
71 touch panel
8 Printer
9 air supply pump
10 exhaust valve
111 gear drive motor
112 brake electromagnet
12 pressure detection circuit
13 pulse detection circuit
14 micro-computer
141 CPU
15 external memory.
Claims (6)
1. An automatic blood pressure measuring device, comprising:
a first decompression unit configured to decompress the pressure of the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of a living body is compressed using the cuff;
a blood pressure determination unit configured to determine a blood pressure value of the living body based on a heart rhythm synchronization wave obtained before the blood pressure determination is completed;
a second decompression unit configured to continue decompression of the pressure in the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of the living body is compressed using the cuff;
a heart rate cycle correlation value detection unit that successively detects a heart rate cycle correlation value based on at least a part of the heart rate synchronous waves obtained before the completion of the blood pressure determination and the heart rate synchronous waves obtained after the completion of the blood pressure determination;
a heart rate cycle correlation value frequency analyzing unit that performs frequency analysis on the fluctuation of the heart rate cycle correlation value detected by the heart rate cycle correlation value detecting unit and calculates a frequency component ratio of the low frequency component to the high frequency component;
a unit for storing and outputting the calculated frequency component ratios together; and
a unit that determines the degree of stress of the subject from the frequency component ratio.
2. The automatic blood pressure measurement device according to claim 1, comprising:
means for performing a re-measurement or a warning of an abnormality in blood pressure when the degree of tension at the time of the determination of the subject exceeds a predetermined reference value.
3. An automatic blood pressure measuring device, comprising:
a first decompression unit configured to decompress the pressure of the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of a living body is compressed using the cuff;
a blood pressure determination unit configured to determine a blood pressure value of the living body based on a heart rhythm synchronization wave obtained before the blood pressure determination is completed;
a second decompression unit configured to continue decompression of the pressure in the cuff until completion of blood pressure determination to obtain a heart rhythm synchronization wave obtained from an artery when a part of the living body is compressed using the cuff;
a stress level determination unit that determines a stress level of the living body based on the heart rate synchronous wave;
and a blood pressure determining unit which determines the blood pressure value as a final blood pressure value when the tension is in a predetermined reference range.
4. The automatic blood pressure measurement device according to claim 3, wherein the tension determination means includes:
a heart rate cycle correlation value detection unit that successively detects a heart rate cycle correlation value based on at least a part of the heart rate synchronous waves obtained before the completion of the blood pressure determination and the heart rate synchronous waves obtained after the completion of the blood pressure determination;
a heart rate cycle correlation value frequency analyzing unit that performs frequency analysis on the fluctuation of the heart rate cycle correlation value detected by the heart rate cycle correlation value detecting unit and calculates a frequency component ratio of the low frequency component to the high frequency component; and
a unit that determines the degree of stress of the subject from the frequency component ratio.
5. The automatic blood pressure measurement device according to claim 4, wherein the tension determination unit further includes:
and a unit for storing and outputting the calculated frequency component ratio.
6. The automatic blood pressure measurement device according to any one of claims 3 to 5, comprising:
means for performing a re-measurement or a warning of an abnormality in blood pressure when the degree of tension at the time of the determination of the subject exceeds a predetermined reference value.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2018144163 | 2018-07-31 | ||
| JP2018-144163 | 2018-07-31 |
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| CN110772242A true CN110772242A (en) | 2020-02-11 |
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| CN201811433026.XA Pending CN110772242A (en) | 2018-07-31 | 2018-11-28 | Automatic blood pressure measuring device with autonomic nerve analysis function |
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| JP (1) | JPWO2020026647A1 (en) |
| CN (1) | CN110772242A (en) |
| WO (1) | WO2020026647A1 (en) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002034933A (en) * | 2000-07-26 | 2002-02-05 | Nippon Colin Co Ltd | Postoperative recovery state evaluating device |
| JP2003265420A (en) * | 2002-03-15 | 2003-09-24 | Terumo Corp | Hemodynamometer with arterial pressure pulse wave analyzing function using brachium pressurizing method |
| JP5173251B2 (en) * | 2007-05-11 | 2013-04-03 | テルモ株式会社 | Pulsation fluctuation measuring apparatus and information processing method thereof |
| CN101366627B (en) * | 2008-09-26 | 2010-06-23 | 鲁东大学 | Electrosphygmomanometer capable of prompting confidence level of blood pressure result of measurement |
| JP5584111B2 (en) * | 2010-12-28 | 2014-09-03 | 株式会社エー・アンド・デイ | Automatic blood pressure measurement device |
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2018
- 2018-11-28 CN CN201811433026.XA patent/CN110772242A/en active Pending
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2019
- 2019-06-25 WO PCT/JP2019/025215 patent/WO2020026647A1/en active Application Filing
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| JPWO2020026647A1 (en) | 2021-08-02 |
| WO2020026647A1 (en) | 2020-02-06 |
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