CN110760421A - Cordyceps cicadae health wine and preparation method thereof - Google Patents
Cordyceps cicadae health wine and preparation method thereof Download PDFInfo
- Publication number
- CN110760421A CN110760421A CN201810832565.4A CN201810832565A CN110760421A CN 110760421 A CN110760421 A CN 110760421A CN 201810832565 A CN201810832565 A CN 201810832565A CN 110760421 A CN110760421 A CN 110760421A
- Authority
- CN
- China
- Prior art keywords
- wine
- cordyceps
- health
- cordyceps sobolifera
- sobolifera
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000014101 wine Nutrition 0.000 title claims abstract description 62
- 241001625026 Cordyceps cicadae Species 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 241000357408 Ophiocordyceps sobolifera Species 0.000 claims abstract description 54
- 239000002994 raw material Substances 0.000 claims abstract description 20
- 241000037831 Polygonatum sibiricum Species 0.000 claims abstract description 5
- 238000003756 stirring Methods 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 238000002791 soaking Methods 0.000 claims description 9
- 241000931705 Cicada Species 0.000 claims description 8
- 241000233866 Fungi Species 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 235000020097 white wine Nutrition 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 abstract description 7
- 230000036039 immunity Effects 0.000 abstract description 7
- 230000000694 effects Effects 0.000 description 17
- 238000000605 extraction Methods 0.000 description 15
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 12
- 239000013642 negative control Substances 0.000 description 12
- 241000699666 Mus <mouse, genus> Species 0.000 description 9
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 6
- 229960005305 adenosine Drugs 0.000 description 6
- 239000012153 distilled water Substances 0.000 description 4
- 230000000242 pagocytic effect Effects 0.000 description 4
- 241000190633 Cordyceps Species 0.000 description 3
- 241000287828 Gallus gallus Species 0.000 description 3
- 206010057249 Phagocytosis Diseases 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000002949 hemolytic effect Effects 0.000 description 3
- 210000002540 macrophage Anatomy 0.000 description 3
- 230000008782 phagocytosis Effects 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 241001264174 Cordyceps militaris Species 0.000 description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 235000013402 health food Nutrition 0.000 description 2
- 238000007689 inspection Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 description 1
- 108010006464 Hemolysin Proteins Proteins 0.000 description 1
- 229930195725 Mannitol Natural products 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000819999 Nymphes Species 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- JAWMENYCRQKKJY-UHFFFAOYSA-N [3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-ylmethyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]methanone Chemical compound N1N=NC=2CN(CCC=21)CC1=NOC2(C1)CCN(CC2)C(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F JAWMENYCRQKKJY-UHFFFAOYSA-N 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 210000000628 antibody-producing cell Anatomy 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 1
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 239000003228 hemolysin Substances 0.000 description 1
- 230000011132 hemopoiesis Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000037356 lipid metabolism Effects 0.000 description 1
- 235000010355 mannitol Nutrition 0.000 description 1
- 239000000594 mannitol Substances 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 210000004988 splenocyte Anatomy 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 229940035893 uracil Drugs 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Insects & Arthropods (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Nutrition Science (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention provides cordyceps cicadae miq health care wine and a preparation method thereof, wherein the cordyceps cicadae miq health care wine is prepared from the following raw materials: 1.0-15% of cordyceps sobolifera sporophore, 0.1-6% of polygonatum sibiricum and 80-98.6% of white spirit. The health wine has immunity enhancing effect.
Description
Technical Field
The invention relates to cordyceps sobolifera health-care wine and a preparation method thereof, belonging to the field of food processing.
Background
Cordyceps cicadae (Isaria cicadae Miquel), belonging to Cordyceps family, is a Cordyceps fungus formed after Isaria cicadae Miquel infects cicada nymph larva, and its main components include adenosine, Cordyceps polysaccharide, cordycepic acid (mannitol), cordycepin, uracil, sterol, alkaloid, vitamins, inorganic salts, mineral elements, etc. The cicada fungus has unique and wide efficacies, such as improving renal function, resisting tumor, regulating immune system, nourishing and strengthening, improving cell capacity, resisting fatigue, reducing blood pressure and blood sugar, relieving fever, easing pain, improving sleep, improving lipid metabolism, promoting hematopoiesis, resisting fungi, resisting aging and the like.
China is a hometown of wine and one of the earliest countries in the world for brewing wine. According to the annual report (northern liquor) of the liquor market in 2016, the yield of the health-preserving liquor in 2016 years in China is 80 ten thousand tons, the production value scale is over 200 hundred million yuan, and the wine is developed at an accelerated rate of 30% per year. Therefore, the health-preserving wine has great expansion space in China, and various large wine industry groups are actively distributing to the health-preserving wine market. The cordyceps sobolifera health wine is brewed by using the unique nutrition and health care effects of cordyceps sobolifera and superior base wine, and has the health care effect and excellent taste.
Disclosure of Invention
The invention aims to provide cordyceps sobolifera health-care wine and a preparation method thereof.
As one aspect of the invention, the invention provides cordyceps sobolifera health-care wine which is prepared from the following raw materials: 1.0-15% of cordyceps sobolifera sporophore, 0.1-6% of polygonatum sibiricum and 80-98.6% of white spirit.
Preferably, the cordyceps sobolifera health-care wine is prepared from the following raw materials: 1.2-12% of cordyceps sobolifera sporophore, 0.12-5% of polygonatum sibiricum and 85-97.8% of white spirit.
Further preferably, the cordyceps sobolifera health-care wine is prepared from the following raw materials: 2.65% of cordyceps sobolifera fruiting body, 0.29% of rhizoma polygonati and 97.06% of white spirit;
or, cicada fungus fruiting body 1.33%, rhizoma Polygonati 0.14%, and Chinese liquor 98.53%;
or 2.0% of cordyceps sobolifera fruiting body, 0.2% of rhizoma polygonati and 97.8% of white spirit;
or 2.4% of cordyceps sobolifera fruiting body, 0.24% of rhizoma polygonati and 97.36% of white spirit.
The rhizoma Polygonati is wine processed rhizoma Polygonati.
The cordyceps sobolifera fruiting body is a dried cordyceps sobolifera fruiting body; further, the water content of the dried cordyceps sobolifera sporocarp product is lower than 6%.
The concentration of the white spirit is 42 to 65 degrees; preferably, the concentration of the white spirit is 42 to 52 degrees; most preferably, the concentration of the white spirit is 42 degrees.
The percentages are weight percentages.
As another aspect of the invention, the invention provides a preparation method of cordyceps sobolifera health-care wine, which comprises the following steps:
adding Cordyceps cicadae fruiting body and rhizoma Polygonati into Chinese liquor base liquor at a certain proportion, stirring regularly, soaking for 60 days, filtering to remove Cordyceps cicadae and rhizoma Polygonati, blending the filtered sake with pure water to obtain a health wine with alcohol degree of 38 degree, bottling and storing.
The preparation method specifically comprises the steps of adding dried cordyceps sobolifera sporocarp and wine-roasted rhizoma polygonati into white spirit base wine in proportion, and stirring for 1-3 times every day in the soaking process, wherein each time is 2-5 min, and the frequency is 10 revolutions per minute.
The soaking time is controlled at 60 days, and the wine base is filtered after 60 days.
① the unique nutrition and health care efficacy of cicada fungus is utilized, and the medicinal and edible rhizoma polygonati raw material is compounded to prepare the health care wine with the effect of enhancing immunity and health care, ② the invention optimizes the soaking process through experiments, increases the stirring step, can greatly improve the extraction rate and shortens the production period.
Detailed Description
Example 1
The cordyceps cicadae miq health wine is prepared from the following raw materials: 2.65% of cordyceps sobolifera fruiting body, 0.29% of wine-roasted rhizoma polygonati and 97.06% of 42-degree white spirit.
The preparation method comprises the following steps:
weighing Cordyceps cicadae fruiting body and wine-roasted rhizoma Polygonati, adding the raw materials into the base liquor of Chinese liquor in proportion, setting a stirrer to stir once a day with stirring frequency of 10 r/min, and stirring for two minutes; soaking for 60 days, filtering to remove periostracum Cicadae and rhizoma Polygonati, blending the filtered sake with pure water to obtain 38 degree health wine, bottling and storing.
Example 2
The cordyceps cicadae miq health wine is prepared from the following raw materials: 1.33 percent of cicada fungus fruit body, 0.14 percent of wine-roasted rhizoma polygonati and 98.53 percent of 42-degree white spirit.
The preparation method is the same as example 1.
Example 3
The cordyceps cicadae miq health wine is prepared from the following raw materials: 3.28 percent of cordyceps sobolifera fruiting body, 0.36 percent of wine-roasted rhizoma polygonati and 96.36 percent of 52-degree white spirit.
The preparation method is the same as example 1.
Example 4
The cordyceps cicadae miq health wine is prepared from the following raw materials: 4.93 percent of cicada fungus body, 0.53 percent of wine-roasted rhizoma polygonati and 94.54 percent of 52-degree white spirit.
The preparation method is the same as example 1.
Example 5
The cordyceps cicadae miq health wine is prepared from the following raw materials: 2.65% of cordyceps sobolifera fruiting body, 0.29% of wine-roasted rhizoma polygonati and 97.06% of 38-degree white spirit.
The preparation method is the same as example 1.
Example 6
The cordyceps cicadae miq health wine is prepared from the following raw materials: 2.65% of cordyceps sobolifera fruiting body, 0.29% of wine-roasted rhizoma polygonati and 97.06% of 52-degree white spirit.
The preparation method is the same as example 1.
Example 7
The cordyceps cicadae miq health wine is prepared from the following raw materials: 2.65% of cordyceps sobolifera fruiting body, 0.29% of wine-roasted rhizoma polygonati and 97.06% of 65-degree white spirit.
The preparation method is the same as example 1.
Example 8
The formulation is the same as in example 1;
the preparation method is basically the same as example 1, except that a still immersion method, i.e., no stirring, is adopted, and the other methods are the same.
Example 9
The cordyceps cicadae miq health wine is prepared from the following raw materials: 2.94 percent of cordyceps sobolifera sporocarp and 97.06 percent of 42-degree white spirit.
The preparation method comprises the following steps:
weighing cordyceps sobolifera sporophore, adding the cordyceps sobolifera sporophore into the white spirit base wine, setting a stirrer to stir once a day, wherein the stirring frequency is 10 revolutions per minute, and stirring for two minutes; filtering cicada fungus after soaking for 60 days, blending the filtered sake with pure water to obtain a health wine with the alcoholic strength of 38 degrees, and bottling for storage.
Measurement of content of functional component
The cordyceps sobolifera health-care wine prepared in the example 1-8 is respectively taken and subjected to functional component (adenosine) detection, and the results are shown in table 1.
TABLE 1 detection result of functional ingredients of Cordyceps cicadae Miquel health wine
The extraction ratio calculation mode is as follows: w ═ x b/a
w: extraction ratio (μ g/g);
x: adenosine content measurements (. mu.g/ml) (60 day values for examples 1-7 and 100 day values for example 8);
b: the b value of each example is 100ml calculated by 100g of total amount;
a: the weight of the dried cordyceps sobolifera fruiting body (the total amount of each example is calculated according to 100g, namely the weight of the cordyceps sobolifera is 100 g).
Table 1 shows that the extraction times of examples 1-7 have peaked at about 60 days for adenosine extraction, while the extraction time of example 8 is about 100 days. Therefore, the extraction treatment modes and the extraction time are different, namely, the stirrer is arranged to stir once a day, the stirring frequency is 10 revolutions per minute, and the stirring method for two minutes is obviously beneficial to shortening the extraction time of adenosine, so that the cost is saved.
It can be seen from the extraction ratios that the extraction ratios of examples 1 and 2 are significantly higher than those of the other groups, from which it can be seen that the different extraction rates, i.e. the use of a base wine with an alcohol content of 42 degrees at a given formulation, are most beneficial for the extraction of adenosine.
Results of functional evaluation
According to the extraction effect (extraction ratio), the health product in example 1 and example 9 is further selected to carry out the immunity enhancing function experiment, and the results are as follows; the test method refers to "health food inspection and evaluation technical Specification" P22-34 (2003 edition), Ministry of health of the people's republic of China, 2 months in 2003.
1 Effect of Cordyceps cicadae Miquel wine on mouse antibody-producing cells
Compared with a negative control group, the cordyceps sobolifera compatible yellow sperm wine can improve the number of hemolytic plaques (P is less than 0.05) of mice, and the effect is obviously better than that of the cordyceps sobolifera soaked wine which is singly used, and the result is shown in table 2.
TABLE 2 Effect on the number of hemolytic plaques in mice
| Group of | Dosage (g/kg) | Number of hemolytic plaques (number of plaques/number of whole splenocytes) |
| Negative control group | Distilled water | 41.3±10.2 |
| EXAMPLE 1 group | 0.9 | 54.8±12.7* |
| EXAMPLE 9 group | 0.9 | 48.6±13.0 |
P <0.05 compared to negative control group
2 Effect of Cordyceps cicadae Miquel wine on mouse serum hemolysin
Compared with a negative control group, the cordyceps sobolifera compatible rhizoma polygonati wine can improve the antibody accumulation (P is less than 0.05), the effect is obviously better than that of the cordyceps sobolifera soaked wine which is singly used, and the result is shown in table 3.
TABLE 3 Effect on mouse antibody accumulation
| Group of | Dosage (g/kg) | Number of antibody products |
| Negative control group | Distilled water | 15.6±4.8 |
| EXAMPLE 1 group | 0.9 | 20.6±5.7* |
| EXAMPLE 9 group | 0.9 | 17.4±5.2 |
P <0.05 compared to negative control group
3 influence of cordyceps sobolifera wine on clearance of mouse carbon
Compared with a negative control group, the cordyceps sobolifera compatible goldmine can improve the phagocytic index (P is less than 0.01) of a mouse, and the effect is obviously better than that of the cordyceps sobolifera soaked wine which is singly used, and the result is shown in a table 4.
TABLE 4 Effect on mouse carbon clearance
| Group of | Dosage (g/kg) | Phagocytic index |
| Negative control group | Distilled water | 4.25±0.53 |
| EXAMPLE 1 group | 0.9 | 5.02±0.57** |
| EXAMPLE 9 group | 0.9 | 4.86±0.67* |
P <0.05, P <0.01, compared to negative controls
4 influence of cordyceps sobolifera wine on phagocytosis of chicken red blood cells by macrophages in abdominal cavity of mouse
Compared with a negative control group, the cordyceps cicadae flower and cordyceps militaris combination yellow essence wine can improve the chicken erythrocyte phagocytosis capability of mouse macrophages, has difference in statistical result (P is less than 0.05), and has obviously better effect than that of the cordyceps cicadae flower and cordyceps militaris soaking wine which is singly used, and the result is shown in table 5.
TABLE 5 Effect on the phagocytic Capacity of mouse macrophages to phagocytose chicken erythrocytes
| Group of | Dosage (g/kg) | Percentage of phagocytosis (%) | Phagocytic index |
| Negative control group | Distilled water | 0.49±0.04 | 0.23±0.04 |
| EXAMPLE 1 group | 0.9 | 0.59±0.05** | 0.28±0.06* |
| EXAMPLE 9 group | 0.9 | 0.52±0.05 | 0.24±0.05 |
P <0.05, P <0.01, compared to negative controls
Conclusion
According to the judgment of the result of the immunity enhancing function test specified in 2003 edition of China 'health food inspection and evaluation technical Specification', the cordyceps sobolifera and the sealwort wine have a synergistic effect on enhancing the immunity under the test condition, have an obvious effect of enhancing the immunity of the organism and have an effect obviously superior to that of the conventional single use of cordyceps sobolifera soaked wine.
Through detection, the cordyceps sobolifera health-care wine prepared in the examples 2-8 has the obvious effect of enhancing the immunity.
Claims (10)
1. The cordyceps cicadae miq health wine is characterized by being prepared from the following raw materials: 1.0-15% of cordyceps sobolifera sporophore, 0.1-6% of polygonatum sibiricum and 80-98.6% of white spirit.
2. The cordyceps sobolifera health-care wine as claimed in claim 1, which is prepared from the following raw materials: 1.2-12% of cordyceps sobolifera sporophore, 0.12-5% of polygonatum sibiricum and 85-97.8% of white spirit.
3. The cordyceps sobolifera health-care wine as claimed in claim 2, which is prepared from the following raw materials: 2.65% of cordyceps sobolifera fruiting body, 0.29% of rhizoma polygonati and 97.06% of white spirit.
4. The cordyceps sobolifera health-care wine as claimed in claim 2, which is prepared from the following raw materials: 1.33 percent of cicada fungus fruiting body, 0.14 percent of rhizoma polygonati and 98.53 percent of white spirit.
5. The cordyceps sobolifera health-care wine as claimed in claim 2, which is prepared from the following raw materials: 2.0% of cordyceps sobolifera fruiting body, 0.2% of rhizoma polygonati and 97.8% of white spirit.
6. The cordyceps sobolifera health-care wine as claimed in claim 2, which is prepared from the following raw materials: 2.4 percent of cordyceps sobolifera fruiting body, 0.24 percent of rhizoma polygonati and 97.36 percent of white spirit.
7. The cordyceps sobolifera health wine as claimed in claim 2, wherein the water content of the cordyceps sobolifera fruiting body is lower than 6%.
8. The cordyceps sobolifera health-care wine as claimed in any one of claims 1 to 7, wherein the concentration of the white wine is 42 degrees to 52 degrees.
9. The preparation method of the cordyceps sobolifera health-care wine as claimed in any one of claims 1 to 7, which is characterized by comprising the following steps: adding Cordyceps cicadae fruiting body and rhizoma Polygonati into Chinese liquor base liquor at a certain proportion, stirring regularly, soaking for 60 days, filtering to remove Cordyceps cicadae and rhizoma Polygonati, blending the filtered sake with pure water to obtain a health wine with alcohol degree of 38 degree, bottling and storing.
10. The method according to claim 9, wherein the soaking process is performed by stirring 1-3 times per day for 2-5 min at a frequency of 10 rpm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810832565.4A CN110760421A (en) | 2018-07-26 | 2018-07-26 | Cordyceps cicadae health wine and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810832565.4A CN110760421A (en) | 2018-07-26 | 2018-07-26 | Cordyceps cicadae health wine and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110760421A true CN110760421A (en) | 2020-02-07 |
Family
ID=69327531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810832565.4A Pending CN110760421A (en) | 2018-07-26 | 2018-07-26 | Cordyceps cicadae health wine and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110760421A (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1124626A (en) * | 1994-02-02 | 1996-06-19 | 汪景山 | Cordyceps liquor |
| CN105010680A (en) * | 2015-08-11 | 2015-11-04 | 亳州千草药业有限公司 | Worm grass sealwort tea and preparing method thereof |
| KR20170015618A (en) * | 2015-07-29 | 2017-02-09 | 제천한약영농조합법인 | Functional alcoholic liquors using cordyceps mushroomand method of producing the same |
| CN107183679A (en) * | 2017-04-28 | 2017-09-22 | 浙江省亚热带作物研究所 | A kind of cordyceps sinensis instant, tablet and cordyceps militaris liquor for adjusting immunologic function |
| CN107183676A (en) * | 2017-04-17 | 2017-09-22 | 安徽虫草源生物科技有限公司 | A kind of Periostracum cicadae lozenge and preparation method thereof |
| CN107574099A (en) * | 2016-10-04 | 2018-01-12 | 李发 | The preparation method of cordyceps sinensis Whisky health-care wine |
-
2018
- 2018-07-26 CN CN201810832565.4A patent/CN110760421A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1124626A (en) * | 1994-02-02 | 1996-06-19 | 汪景山 | Cordyceps liquor |
| KR20170015618A (en) * | 2015-07-29 | 2017-02-09 | 제천한약영농조합법인 | Functional alcoholic liquors using cordyceps mushroomand method of producing the same |
| CN105010680A (en) * | 2015-08-11 | 2015-11-04 | 亳州千草药业有限公司 | Worm grass sealwort tea and preparing method thereof |
| CN107574099A (en) * | 2016-10-04 | 2018-01-12 | 李发 | The preparation method of cordyceps sinensis Whisky health-care wine |
| CN107183676A (en) * | 2017-04-17 | 2017-09-22 | 安徽虫草源生物科技有限公司 | A kind of Periostracum cicadae lozenge and preparation method thereof |
| CN107183679A (en) * | 2017-04-28 | 2017-09-22 | 浙江省亚热带作物研究所 | A kind of cordyceps sinensis instant, tablet and cordyceps militaris liquor for adjusting immunologic function |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Maftoun et al. | The edible mushroom Pleurotus spp.: I. Biodiversity and nutritional values | |
| CN103571726B (en) | A kind of Noni health-care wine and brewing method thereof | |
| CN105087279A (en) | Health-care pumpkin wine and making method thereof | |
| CN102669558A (en) | Cordyceps militaris flour and manufacturing method thereof | |
| CN104188015B (en) | A kind of Woman's health-care beverage prepared by Flos Camelliae sinensis and pueraria root powder | |
| CN109452552B (en) | Monascus fermented anti-fatigue oat and buckwheat and preparation method thereof | |
| CN107114645A (en) | A kind of hawthorn lotus leaf cassia seed ultra micro powder solid beverage, preparation method and applications | |
| WA et al. | Bioactive potential of some fascinating edible mushrooms Macrolepiota, Russula, Amanita, Vovariella and Grifola as a treasure of multipurpose therapeutic natural product | |
| CN105861229A (en) | Fatigue-relieving rice wine and preparing method thereof | |
| CN102342487A (en) | Local flavor mulberry jam | |
| CN111328948A (en) | Ginger paste and preparation method thereof | |
| CN110760421A (en) | Cordyceps cicadae health wine and preparation method thereof | |
| CN106561826A (en) | Method for preparing red date-Chinese wolfberry functional type blended milk | |
| CN106720801B (en) | Burdock tea rich in inulin | |
| KR101877229B1 (en) | Rice Cake Containing Asparagus and Shiso Leaf and Manufacturing Method thereof | |
| CN108576346A (en) | A kind of Inonotus obliquus pressed candy of energy anticancer reducing pressure and sugar reducing blood lipid | |
| CN107897918A (en) | A kind of ginkgo ganoderma concentrate and preparation method thereof | |
| CN113180243A (en) | Ginseng and radix puerariae paste plant composition and preparation method thereof | |
| CN104286283A (en) | Production method of Brassica rapa L. anti-hypoxic fruit tea | |
| CN113349317A (en) | Fig composite functional beverage and preparation method and application thereof | |
| CN111067063A (en) | Processing method of frozen hericium erinaceus products | |
| KR20170077640A (en) | Composition for Relaxing Stress and Immunopotentiating Using Red Ginseng Power, etc. | |
| CN111802541A (en) | Traditional Chinese medicine plant beverage and preparation method thereof | |
| Mongkontanawat et al. | Product development of mushroom beverage with high β-glucan content from local mushrooms. | |
| KR102356922B1 (en) | Method of manufacturing of immune-enhancing Kimchi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200207 |