CN110755759A - Cavity drainage tube with built-in assembled radioactive particle carrier - Google Patents

Cavity drainage tube with built-in assembled radioactive particle carrier Download PDF

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Publication number
CN110755759A
CN110755759A CN201910974957.9A CN201910974957A CN110755759A CN 110755759 A CN110755759 A CN 110755759A CN 201910974957 A CN201910974957 A CN 201910974957A CN 110755759 A CN110755759 A CN 110755759A
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CN
China
Prior art keywords
tube
cavity
particle
built
drainage
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Pending
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CN201910974957.9A
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Chinese (zh)
Inventor
阎尔坤
白红升
闫小强
崔贝
马英喆
贾通
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Tianjin Co Ltd Of Saden Medicine Research Academy
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Tianjin Co Ltd Of Saden Medicine Research Academy
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Priority to CN201910974957.9A priority Critical patent/CN110755759A/en
Publication of CN110755759A publication Critical patent/CN110755759A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002Intraluminal radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0057Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention discloses a cavity drainage tube with a built-in assembled radioactive particle carrier, which comprises a tube body, wherein the right end of the tube body penetrates through a connecting head, the diameter of the left end of the tube body is arranged in a small manner, a fixing ring is arranged on the connecting head, a drainage cavity is arranged in the tube body, the assembled radioactive particle carrier is also arranged in the tube body, the assembled radioactive particle carrier comprises a particle cavity tube and a particle cavity tube clamping plate, and the particle cavity tube penetrates through the particle cavity tube clamping plate. The invention not only realizes the function of separating the drainage treatment from the radiotherapy, but also has the advantages that the inner radiation part is an assembly structure, the assembly is simple and easy to operate, and a larger drainage space is provided. The invention can assemble the assembled radioactive particle carrier in vitro, and can install, replace and adjust the position of the radioactive particle, and has the advantages of simple operation of medical personnel, short time consumption, less pain of patients, low manufacturing cost of products and the like.

Description

Cavity drainage tube with built-in assembled radioactive particle carrier
Technical Field
The invention relates to the field of medical materials, in particular to a cavity drainage tube with a built-in assembled radioactive particle carrier.
Background
The cavity drainage tube is a medical instrument commonly used after a clinical major operation, and is mainly used for guiding pus, blood or other liquid accumulated in human tissues or in a body cavity out of the body, reducing the infection risk of a patient and improving the life quality. The malignant obstructive jaundice is a common disease difficult to treat clinically, and is mainly cholestasis and liver damage caused by pressing or invading common bile duct, common hepatic duct and main trunks of left and right hepatic ducts of hepatic duct cancer, pancreatic cancer, liver cancer and metastatic cancer. Due to the unique location of the tumor, surgical resection is difficult and risky, and most patients can only achieve symptomatic relief by palliative drainage.
The drainage technologies commonly used in clinic at present are a biliary drainage technology through a percutaneous transhepatic puncture route and a biliary stent technology developed on the basis of catheter drainage. A large number of clinical experiments show that the two technologies have obvious effect on bile drainage, can effectively relieve the pain of patients, cannot inhibit the growth of tumors and can not eradicate the tumor focus of the patients.
Brachytherapy is considered to be a simple and effective method for tumor therapy, in which radioactive seeds are implanted into a tumor, and the tumor is irradiated with radiation from a radioactive source for a long time, so as to kill or kill tumor cells. Based on this, the near-distance irradiation treatment technology and the biliary drainage technology are combined, and the development of a technology capable of fundamentally solving the tumor focus of the patient becomes the urgent need of the patients.
Chinese patent CN 101695458A (published: 4/21/2010) discloses a biliary tract radiotherapy stent. The stent designed by the patent not only can keep the bile duct smooth through radial support, but also can kill tumor cells and inhibit tumor proliferation. However, when the product of the patent is used, the inner and outer brackets and the radioactive particles need to be placed in the narrow bile duct of the human body step by step, the operation is complex, and the success rate is low; in addition, the stent is easy to be blocked when in use, so that the actual opening time is short, and the inner stent and the outer stent are made of nickel-titanium metal, so the stent is expensive in manufacturing cost and difficult to popularize.
Chinese patent CN 203677727U (published: 7/2/2014) discloses a three-cavity biliary tract drainage catheter capable of carrying radioactive particles. This patent has redesigned the structure of drainage tube, keeps somewhere two radioactive particle cavitys next to the drainage cavitys, has changed the single drainage function of traditional drainage tube for drainage and radiotherapy can go on simultaneously. During treatment, the drainage tube is inserted into a bile duct of a human body, and then the pushing and guiding needle is used for guiding in and adjusting the position of radioactive particles, and the guiding in and the adjusting of the position of the particles are very difficult due to the integrated structural design of the drainage tube and the complex human body structure; in addition, if particle replacement is carried out, the replacement of a new drainage tube is often required to be operated again, which brings great pain to the patient.
Disclosure of Invention
The invention overcomes the defects of the prior art and provides a cavity drainage tube with a built-in assembled radioactive particle carrier.
The second purpose of the invention is to provide a second cavity drainage tube with built-in assembled radioactive particle carriers.
The technical scheme of the invention is summarized as follows:
the utility model provides a built-in assembled radioactive particle carrier's chamber says drainage tube, includes body 1, and the right-hand member of body runs through the setting of connector 3, and the pipe diameter of the left end of body is chang xiao to be set up, is provided with solid fixed ring 13 on the connector, is provided with drainage chamber in the body and says 7, still is provided with assembled radioactive particle carrier 2 in the body, and assembled radioactive particle carrier includes that particle chamber says that 6 and particle chamber say that pipe cardboard 9, and particle chamber says that 6 runs through particle chamber says that pipe cardboard 9 sets up.
Better, the left end dish of body revolves the setting.
The cross section of the connector is oval or round.
Or, a thread guide hole 11 is arranged at the near left end of the tube body 1, a thread guide 12 is arranged in the tube body 1, one end of the thread guide 12 penetrates through the thread guide hole 11 from the tube body 1 and then is connected with the tail end of the spiral part, and the other end of the thread guide 12 penetrates out of the right end of the tube body and is movably connected with a fixing ring 13.
Preferably, the tube body is provided with a side hole 5 which runs through the drainage cavity.
The inner surface of the pipe body is provided with a limiting plate 8.
The number of the particle cavity channel pipes 6 is 1-8, the number of the particle cavity channel pipe clamping plates 9 is at least 2, and the cross sections of the particle cavity channel pipe clamping plates 9 are in a straight line shape, a cross shape, a Y shape, a circular shape or a regular triangle shape.
The cavity drainage tube of built-in assembled radioactive particle carrier of second kind, including second body 21, the right-hand member of second body runs through second connector 23 and sets up, the left end of second body is connected with bifurcated pipe 34 or bifurcated pipe 35, the pipe diameter of the left end of bifurcated pipe or bifurcated pipe is small-size to set up, be provided with the solid fixed ring of second 33 on the second connector, be provided with second drainage cavity way 27 and second assembled radioactive particle carrier 22 in the second body, the assembled radioactive particle carrier of second is formed by the equipment of second particle cavity way pipe 26 and second particle cavity way pipe cardboard 29, be provided with the second side opening 25 that link up second drainage cavity way on the second body, on the bifurcated pipe or on the bifurcated pipe.
The cross section of the second connector is oval or round.
The inner surface of the second pipe body is provided with a second limiting plate 28.
The number of the second particle channel pipes 26 is 1-8, the number of the second particle channel pipe clamping plates 29 is at least 2, and the cross section of each particle channel pipe clamping plate 29 is in a straight line shape, a cross shape, a Y shape, a circle shape or a regular triangle shape.
The invention has the beneficial effects that:
① the invention not only realizes the function of separating the drainage therapy and the radiotherapy, but also has the inner radiation part of an assembly structure, simple assembly and easy operation, and has larger drainage space.
② the invention can assemble the assembled radioactive particle carrier in vitro, and install, replace and adjust the position of the radioactive particle, and has the advantages of simple operation, short time consumption, less pain for patients, low cost of products, etc.
Drawings
FIG. 1 is a schematic view of a cavity drainage tube with a built-in assembly type radioactive particle carrier according to the present invention.
FIG. 2 is a cross-sectional view of a catheter body of a cavity drainage catheter with a built-in assembly type radioactive particle carrier.
FIG. 3 is a schematic cross-sectional view of a catheter body part with a limiting plate arranged on the inner surface of the catheter for holding the assembled radioactive particle carrier and passing through the side hole.
FIG. 4 is a schematic view of the cavity drainage tube with built-in assembled radioactive particle carrier of the present invention, which is provided with a guide wire and two ends of the guide wire connected together.
FIG. 5 is a schematic view of a second cavity drainage tube with a built-in assembly type radioactive particle carrier according to the present invention, wherein FIG. 5A is a schematic view of a left end of a second tube connected to a bifurcated tube; FIG. 5B is a schematic view of the left end of the second tube being connected to the Y-tube; FIG. 5C is a schematic view of the second tube body being connected to the two-way tube at the left end and the two-way tube being spirally disposed.
FIG. 6 is a schematic cross-sectional view of a second cavity drainage tube with a built-in assembly type radioactive particle carrier.
FIG. 7 is a schematic diagram showing an assembled three-dimensional structure of an assembled radioactive particle carrier disposed in a tube.
FIG. 8 is a schematic three-dimensional structure of a tube and a connector of a drainage tube of a cavity with a built-in assembly type radioactive particle carrier.
FIG. 9 is a schematic three-dimensional structure diagram of a tube body and a connector of a second cavity drainage tube with an assembled radioactive particle carrier inside.
Detailed Description
The invention is further illustrated by the following figures.
The utility model provides a built-in assembled radioactive particle carrier's chamber says drainage tube (see figure 1, 2, 3 and 7), includes body 1, and the right-hand member of body runs through connector 3 and sets up, and the pipe diameter of the left end of body is provided with solid fixed ring 13 on the connector, is provided with drainage chamber way 7 in the body, still is provided with assembled radioactive particle carrier 2 in the body, and assembled radioactive particle carrier includes that particle chamber says that pipe 6 and particle chamber say that pipe cardboard 9, and particle chamber says that pipe 6 runs through particle chamber says that cardboard 9 sets up.
Preferably, the left end of the tube body is coiled (see fig. 4). The invention can be prevented from falling off after being placed in the treatment part of the body.
The cross section of the connecting head is oval or round (figure 8).
Or, a guide wire hole 11 is arranged at the near left end of the tube body 1, a guide wire 12 is arranged in the tube body 1, one end of the guide wire 12 penetrates through the guide wire hole 11 from the tube body 1 and then is connected with the tail end of the spiral part, and the other end of the guide wire 12 penetrates out of the right end of the tube body and is movably connected with a fixing ring 13 to prevent falling off (see fig. 4).
Preferably, the tube body is provided with a side hole 5 which runs through the drainage cavity.
The inner surface of the pipe body is provided with a limiting plate 8. The two limiting plates form a limiting plate pair (fig. 3), and the assembled radioactive particle carrier is limited within the limiting plate pair.
The number of the particle channel pipes 6 is 1, 2, 3, 4, 5, 6, 7 and 8, the particle channel pipe clamping plates 9 are at least 2, and can also be 3, 4, 5, 6 and the like, and the cross sections of the particle channel pipe clamping plates 9 are in a straight line shape, a cross shape, a Y shape, a circle shape or a regular triangle shape.
The arrangement of side opening is avoided limiting plate to setting up, avoids assembled radioactive particle carrier to the jam of side opening, and the preferred 6 of side opening number.
The material of the pipe body is preferably polyether polyurethane, silicon rubber, polyester, polymethyl methacrylate, polyvinyl chloride or polypropylene.
Radioactive particles such as cesium 131, yttrium 90, phosphorus 32, palladium 103, gold 198, iodine 125 or ytterbium 169, preferably iodine 125.
The second cavity drainage tube (figure 6) with the built-in assembled radioactive particle carrier comprises a second tube body 21, the right end of the second tube body penetrates through a second connector 23, the left end of the second tube body is connected with a bifurcated tube 34 (figure 5A) or a bifurcated tube 35 (figure 5B), the tube diameter of the left end of the bifurcated tube or the bifurcated tube is small, and the left end of the bifurcated tube or the bifurcated tube can also be spirally arranged (figure 5C) to prevent the device from falling off after being placed in a treatment part of a machine body.
The second fixing ring 33 is arranged on the second connecting head, the second drainage cavity channel 27 and the second assembled radioactive particle carrier 22 are arranged in the second pipe body, the second assembled radioactive particle carrier is formed by assembling a second particle channel pipe 26 and a second particle channel pipe clamping plate 29, and a second side hole 25 penetrating through the second drainage cavity channel is formed in the second pipe body, the two fork pipes or the three fork pipes.
The cross section of the second connector is oval or round (see fig. 9).
The inner surface of the second pipe body is provided with a second limiting plate 28.
The number of the second particle channel pipes 26 is 1, 2, 3, 4, 5, 6, 7, 8, the second particle channel pipe clamping plates 29 are at least 2, also can be 3, 4, 5, 6, etc., and the cross section of the particle channel pipe clamping plates 29 is in a straight line shape, a cross shape, a Y shape, a circle or a regular triangle.
The side holes are arranged in a manner of avoiding the limiting plates, so that the side holes are prevented from being blocked by built-in assembled radioactive particle carriers.
The material of the second tube is preferably polyether polyurethane, silicone rubber, polyester, polymethyl methacrylate, polyvinyl chloride or polypropylene.
Second radioactive particles such as cesium 131, yttrium 90, phosphorus 32, palladium 103, gold 198, iodine 125 or ytterbium 169, preferably iodine 125.
The use of the invention:
the radioactive particles are arranged in a particle cavity duct of the assembled radioactive particle carrier in vitro, and the tumor is locally radiated and treated by adjusting the position of the radioactive particle carrier. The number and length of the radioactive particles are determined according to the length of the lesion of the patient, and the activity of the radioactivity is determined according to factors such as the tumor cytology type and the sensitivity to radiotherapy.
The tube body penetrates through the connector, and the right end of the tube body is connected with the syringe or the drainage bag to guide accumulated pus, blood or other liquid out of the body.
When the cavity drainage tube with the built-in assembled radioactive particle carrier is used, firstly, according to factors such as the part, the length and the like of a tumor displayed by imaging, a computer aided Treatment Planning System (TPS) is used for calculating and is used as a reference for installing the number, the position and the coverage length of radioactive particles; secondly, radioactive particles such as iodine 125 particles are installed in the tube body in vitro; a cavity drainage tube with an assembled radioactive particle carrier inside comprises a straight left end, a spiral structure, a bifurcated tube and a bifurcated tube, wherein the left end of the drainage tube is manually straightened and is arranged in a drainage tube conveying pipe; then the drainage tube delivery pipe is inserted into the tumor part of the human body, the drainage tube delivery pipe is taken out, and the drainage tube carrying the radioactive particles is restored and is left in the body for radiotherapy.
The invention not only realizes the function of separating the drainage treatment from the radiotherapy, but also has the advantages that the inner radiation part is an assembly structure, the assembly is simple and easy to operate, and a larger drainage space is provided; meanwhile, the invention can carry out the installation, the replacement and the position adjustment of the radioactive particles in vitro, and has the advantages of simple operation of medical personnel, short time consumption, less pain of patients, low manufacturing cost of products and the like.

Claims (10)

1. The utility model provides a built-in assembled radioactive particle carrier's chamber says drainage tube, includes body (1), and the right-hand member of body runs through connector (3) and sets up, and the pipe diameter of the left end of body is provided with solid fixed ring (13) on the connector, is provided with drainage chamber way (7) in the body, still is provided with assembled radioactive particle carrier (2) in the characterized by body, assembled radioactive particle carrier includes that particle chamber says pipe (6) and particle chamber way pipe cardboard (9), particle chamber says that particle chamber pipe (6) runs through particle chamber way pipe cardboard (9) and sets up.
2. The cavity drainage tube with built-in assembled radioactive particle carrier as claimed in claim 1, wherein the left end of the tube body is spirally disposed.
3. The cavity drainage tube with a built-in assembled radioactive particle carrier as claimed in claim 1, wherein said connector has an oval or circular cross-section.
4. The cavity drainage tube with built-in assembled radioactive particle carrier according to claim 2, wherein a guide wire hole (11) is arranged at the near left end of the tube body (1), a guide wire (12) is arranged in the tube body (1), one end of the guide wire (12) passes through the guide wire hole (11) from the inside of the tube body (1) and then is connected with the tail end of the spiral part, and the other end of the guide wire (12) passes through the right end of the tube body and is movably connected with the fixing ring (13).
5. A cavity drainage tube with built-in assembled radioactive particle carrier according to any of claims 1 to 4, wherein said tube body is provided with a side hole (5) penetrating the drainage cavity.
6. The cavity drainage tube with built-in assembled radioactive particle carrier according to any of claims 1 to 4, wherein the inner surface of said tube body is provided with a stopper (8).
7. The cavity drainage tube for the built-in assembled radioactive particle carriers of claim 1, wherein the number of the particle cavity tubes (6) is 1-8, the number of the particle cavity tube clamping plates (9) is at least 2, and the cross section of each particle cavity tube clamping plate (9) is in a straight line shape, a cross shape, a Y shape, a circle shape or a regular triangle shape.
8. The second cavity of built-in assembled radioactive particle carrier says drainage tube, including second body (21), the right-hand member of second body runs through second connector (23) and sets up, and the left end of second body is connected with bifurcated pipe (34) or bifurcated pipe (35), the pipe diameter of the left end of bifurcated pipe or bifurcated pipe is managed little formula and is set up, is provided with the solid fixed ring of second (33) on the second connector, is provided with second drainage cavity way (27) and second assembled radioactive particle carrier (22) in the second body, and second assembled radioactive particle carrier is formed by the equipment of second particle cavity way pipe (26) and second particle way pipe cardboard (29), be provided with second side opening (25) that link up second drainage cavity way on the second body, on the bifurcated pipe or on the bifurcated pipe.
9. The cavity drainage tube with built-in assembled radioactive particle carrier of claim 8, wherein said second tube has a second stopper plate (28) on its inner surface.
10. The cavity drainage tube for the built-in assembled radioactive particle carriers of claim 8, wherein the number of the second particle channel tubes (26) is 1-8, the number of the second particle channel tube clamping plates (29) is at least 2, and the cross section of each particle channel tube clamping plate (29) is in a straight line shape, a cross shape, a Y shape, a circle shape or a regular triangle shape.
CN201910974957.9A 2019-10-14 2019-10-14 Cavity drainage tube with built-in assembled radioactive particle carrier Pending CN110755759A (en)

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Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077073A2 (en) * 2006-12-19 2008-06-26 Cytyc Corporation Asymmetric radiation dosing devices and methods for brachytherapy
CN103830836A (en) * 2014-03-03 2014-06-04 李玉亮 Drainage catheter capable of carrying radioactive particles
CN203677727U (en) * 2013-12-13 2014-07-02 深圳市库珀科技发展有限公司 Three-cavity structured biliary tract drainage catheter capable of carrying radioactive particles
CN104383620A (en) * 2014-11-20 2015-03-04 上海交通大学医学院附属新华医院 Novel dual-channel peritoneal dialysis catheter suitable for operation under endoscope
CN204745343U (en) * 2015-05-15 2015-11-11 台州市立医院 Biliary tract drainage device that can nimble load active particles
CN204840652U (en) * 2015-07-16 2015-12-09 焦德超 Ureter radiotherapy associated drainage catheter
CN205181985U (en) * 2015-11-30 2016-04-27 山东创新医疗器械科技有限公司 Device is implanted in biliary tract drainage radiation
CN205494666U (en) * 2016-02-19 2016-08-24 张成武 Iodine particle stomach tube of radiation therapy esophagus tumour
CN205494633U (en) * 2015-12-28 2016-08-24 王万胜 Active particles biliary tract drainage
CN209237197U (en) * 2018-12-28 2019-08-13 焦德超 A kind of biliary tract spiral support extends out formula particle conduit component

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008077073A2 (en) * 2006-12-19 2008-06-26 Cytyc Corporation Asymmetric radiation dosing devices and methods for brachytherapy
CN203677727U (en) * 2013-12-13 2014-07-02 深圳市库珀科技发展有限公司 Three-cavity structured biliary tract drainage catheter capable of carrying radioactive particles
CN103830836A (en) * 2014-03-03 2014-06-04 李玉亮 Drainage catheter capable of carrying radioactive particles
CN104383620A (en) * 2014-11-20 2015-03-04 上海交通大学医学院附属新华医院 Novel dual-channel peritoneal dialysis catheter suitable for operation under endoscope
CN204745343U (en) * 2015-05-15 2015-11-11 台州市立医院 Biliary tract drainage device that can nimble load active particles
CN204840652U (en) * 2015-07-16 2015-12-09 焦德超 Ureter radiotherapy associated drainage catheter
CN205181985U (en) * 2015-11-30 2016-04-27 山东创新医疗器械科技有限公司 Device is implanted in biliary tract drainage radiation
CN205494633U (en) * 2015-12-28 2016-08-24 王万胜 Active particles biliary tract drainage
CN205494666U (en) * 2016-02-19 2016-08-24 张成武 Iodine particle stomach tube of radiation therapy esophagus tumour
CN209237197U (en) * 2018-12-28 2019-08-13 焦德超 A kind of biliary tract spiral support extends out formula particle conduit component

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Application publication date: 20200207