CN110742997A - 一种治疗妇科疾病的瑶药提取浓缩液的制备方法 - Google Patents
一种治疗妇科疾病的瑶药提取浓缩液的制备方法 Download PDFInfo
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Abstract
本发明公开了一种治疗妇科疾病的瑶药提取浓缩液的制备方法，属于中药技术领域。所述治疗妇科疾病的瑶药提取浓缩液的制备方法，包括如下步骤：步骤1：称取如下原料，分别粉碎后，混合，得到混合药材；步骤2：将混合药材加入到水中，浸泡后，再加入水，提取1‑3次，每次4h，合并提取液；步骤3：将提取液减压浓缩，得浸膏，罐装，灭菌，即得到治疗妇科疾病的瑶药提取浓缩液。本发明的治疗妇科疾病的瑶药提取浓缩液，由多种中药配制而成，组成合理，配伍得当，各组分的有效成分得以充分释出，具有清热除湿、杀虫止痒、祛风滋阴、理气散结之功效，用于治疗妇科疾病。
Description
技术领域
本发明涉及一种治疗妇科疾病的瑶药提取浓缩液的制备方法，属于中药技术领域。
背景技术
妇科炎症是女性生殖器出现炎症的一种疾病，主要有阴道炎、宫颈炎、尿道炎、宫颈糜烂、外阴瘙痒、白带异常等。据有关流行病学调查结果表明，我国城市妇女已婚女性妇科炎症的发病率高达42.9％，妇科炎症已成为威胁我国女性身体健康的“杀手”之一。
中医将妇科炎症归属于“带下”、“阴痒”、“少腹痛”、“崩漏”等范畴。造成妇科炎症的主要原因多为湿热毒邪乘虚而入，蕴积冲任胞宫，致脏腑气血功能失调。
目前治疗妇科炎症的药物主要分为西药、中药以及中西药结合。西药以抗菌素类为主，这些药物作用虽快，但许多药物可通过阴道粘膜吸收而又对人体引起一定的毒副作用。另外，抗菌素类药物在用于阴道炎时，很容易使阴道菌群改变，导致菌群失调，进而诱发二重感染。中药临床疗效好，副作用小，但疗效不确切，治疗效果缓慢。
药浴对人体具有独到的功效，自古以来一直受医学界重视。目前市场常见的药浴种类主要分为三类，包括：全身浴、坐浴、足浴，使用方法也非常简单，只需要把溶解好的药水倒入调好水温和水量的浴盆或浴桶中，然后把身体泡在水里即可。
鉴于此，有必要提供一种疗效确切、副作用小、见效快的治疗妇科疾病的产品。
发明内容
本发明的目的，是提供一种治疗妇科疾病的瑶药提取浓缩液。本发明的治疗妇科疾病的瑶药提取浓缩液，由多种中药配制而成，组成合理，配伍得当，各组分的有效成分得以充分释出，具有清热除湿、杀虫止痒、祛风滋阴、理气散结之功效，用于治疗妇科疾病。
本发明解决上述技术问题的技术方案如下：一种治疗妇科疾病的瑶药提取浓缩液的制备方法，包括如下步骤：
步骤1：称取如下重量份数的原料：乌药8-12份、益母草8-12份、香附8-12份、川椒8-12份、大血藤8-12份、艾叶8-12份、生姜8-12份、山姜8-12份、香茅8-12份、柚叶8-12份、山鸡椒8-12份、黄皮树皮8-12份和茉莉花8-12份，分别粉碎后，混合，得到混合药材；
步骤2：将步骤1得到的混合药材加入到所述混合药材2-4倍重量的水中，浸泡3-5h后，再加入步骤1得到的混合药材4-6倍重量的水，提取1-3次，每次4h，合并提取液；
步骤3：将步骤2得到的提取液减压浓缩，得浸膏，罐装，灭菌，即得到治疗妇科疾病的瑶药提取浓缩液。
本发明的步骤1选用的原料简介：
乌药，味辛,性温，归肺、脾、肾、膀胱经，有行气止痛、温肾散寒之功效；益母草，味苦、辛,性微寒，归肝、心包、膀胱经，有活血调经、利尿消肿、清热解毒之功效；香附，味辛、微苦、微甘，性平，归肝、脾、三焦经，有疏肝解郁、调经止痛、理气调中之功效；川椒，味辛，性温，归脾、胃、肾经，有温中止痛、燥湿杀虫之功效；大血藤，味苦，性平，归大肠、肝经，有清热解毒、活血通络、祛风止痉之功效；艾叶，味辛、苦，性温，归肝、脾、肾经，有温经止血、散寒止痛、祛湿止痒之功效；生姜，味辛，性微温，归肺、脾、胃经，有解表散寒、温中止呕、化痰止咳之功效；山姜，味辛，性温，归胃、肺经，有祛风通络、理气止痛之功效；香茅，味辛，性微温，有祛风除湿、消肿止痛之功效；柚叶，味辛、苦,性温，归肝、脾经，有行气止痛、解毒消肿之功效；山鸡椒，味辛、微苦，性温，归脾、胃、肾经，有温中止痛、行气活血、平喘、利尿之功效；黄皮树皮，味辛、苦，性温，归胃、肝经，有行气止痛之功效；茉莉花，味辛、微甘,性温，归脾、胃、肝经，有理气止痛、辟秽开郁之功效。以上各原料在发挥单一作用的同时，共奏清热除湿、杀虫止痒、祛风滋阴、理气散结之功效，用于治疗妇科疾病。
本发明的有益效果：
(1)本发明的治疗妇科疾病的瑶药提取浓缩液，由多种中药配制而成，组成合理，配伍得当，各组分的有效成分得以充分释出，具有清热除湿、杀虫止痒、祛风滋阴、理气散结之功效，用于治疗妇科疾病。
(2)本发明的治疗妇科疾病的瑶药提取浓缩液，无毒无副作用，见效快且持久，使用安全可靠。
(3)本发明的治疗妇科疾病的瑶药提取浓缩液的制备方法简单，操作容易，药源广，成本低廉，市场前景广阔，适合推广应用。
在上述技术方案的基础上，本发明还可以做如下改进。
进一步，步骤1中，所述原料的重量份数为：乌药10份、益母草10份、香附10份、川椒10份、大血藤10份、艾叶10份、生姜10份、山姜10份、香茅10份、柚叶10份、山鸡椒10份、黄皮树皮10份和茉莉花10份。
采用上述进一步的有益效果是：各原料采用上述配比，得到的治疗妇科疾病的瑶药提取浓缩液的药效更明显。
进一步，步骤1中，所述粉碎的目数为10-20目。
采用上述进一步的有益效果是：粉碎采用上述参数，得到的治疗妇科疾病的瑶药提取浓缩液的药效更明显。
进一步，步骤3中，所述浸膏在80℃时的相对密度为1.4。
进一步，步骤5中，所述灭菌为高压蒸汽灭菌，压力为(1.0-2.0)×105Pa，温度为100℃，时间为30-120min。
采用上述进一步的有益效果是：灭菌采用上述参数，灭菌的效果更好。
本发明的治疗妇科疾病的瑶药提取浓缩液的使用方法：
取上述治疗妇科疾病的瑶药提取浓缩液，加入到温水(35℃-45℃)中，瑶药提取浓缩液与温水的体积比为1:(20-30),洗浴20min-30min,每日1次。7天为一个疗程，使用1-5个疗程。根据患者病情轻重计算治疗时间，轻度患者使用1个疗程，重病患者使用5个疗程即可痊愈。
具体实施方式
以下结合具体实施例对本发明的原理和特征进行描述，所举实例只用于解释本发明，并非用于限定本发明的范围。
实施例1：
本实施例的治疗妇科疾病的瑶药提取浓缩液的制备方法，包括如下步骤：
步骤1：称取如下重量的原料：乌药8kg、益母草12kg、香附8kg、川椒12kg、大血藤8kg、艾叶12kg、生姜8kg、山姜12kg、香茅8kg、柚叶12kg、山鸡椒8kg、黄皮树皮12kg和茉莉花8kg，分别粉碎至10-20目后，混合，得到混合药材；
步骤2：将步骤1得到的混合药材加入256kg水中，浸泡3h后，再加入512kg的水，提取1次，提取4h，得到提取液；
步骤3：将步骤2得到的提取液减压之浓缩80℃时的相对密度为1.4的浸膏，罐装，在压力为1×105Pa，温度为100℃，高压蒸汽灭菌120min，即得到治疗妇科疾病的瑶药提取浓缩液。
实施例2：
本实施例的治疗妇科疾病的瑶药提取浓缩液的制备方法，包括如下步骤：
步骤1：称取如下重量的原料：乌药10kg、益母草10kg、香附10kg、川椒10kg、大血藤10kg、艾叶10kg、生姜10kg、山姜10kg、香茅10kg、柚叶10kg、山鸡椒10kg、黄皮树皮10kg和茉莉花10kg，分别粉碎至10-20目后，混合，得到混合药材；
步骤2：将步骤1得到的混合药材加入到390kg水中，浸泡4h后，再加入650kg的水，提取2次，每次4h，合并提取液；
步骤3：将步骤2得到的提取液减压之浓缩80℃时的相对密度为1.4的浸膏，罐装，在压力为1.5×105Pa，温度为100℃，高压蒸汽灭菌70min，即得到治疗妇科疾病的瑶药提取浓缩液。
实施例3：
本实施例的治疗妇科疾病的瑶药提取浓缩液的制备方法，包括如下步骤：
步骤1：称取如下重量的原料：乌药12kg、益母草8kg、香附12kg、川椒8kg、大血藤12kg、艾叶8kg、生姜12kg、山姜8kg、香茅12kg、柚叶8kg、山鸡椒12kg、黄皮树皮8kg和茉莉花12kg，分别粉碎至10-20目后，混合，得到混合药材；
步骤2：将步骤1得到的混合药材加入到528kg的水中，浸泡5h后，再加入792kg的水，提取3次，每次4h，合并提取液；
步骤3：将步骤2得到的提取液减压之浓缩80℃时的相对密度为1.4的浸膏，罐装，在压力为2×105Pa，温度为100℃，高压蒸汽灭菌30min，即得到治疗妇科疾病的瑶药提取浓缩液。
临床观察：
本发明人于2015年至今，对45例妇科疾病患者进行临床观察治疗，年龄为22-52岁。
1、治疗方法
分别取实施例1、实施例2或实施例3制备得到的治疗妇科疾病的瑶药提取浓缩液，加入到温水(35℃-45℃)中，瑶药提取浓缩液与温水的体积比为1:(20-30),洗浴20min-30min,每日1次。7天为一个疗程，使用1-5个疗程。根据患者病情轻重计算治疗时间，轻度患者使用1个疗程，重病患者使用5个疗程即可痊愈。
2、治疗标准
(1)治愈：症状、体征及妇检恢复正常。
(2)有效：症状、体症及检查均有改善。
(3)无效：症状、体症均无明显改善，症状如前。
3、临床结果
临床治愈39例(86.67％)，有效4例(8.89％)，无效2例(4.44％)，总有效率为95.56％。
4、典型病例
病例1：章某，女，25岁，白带色黄伴下腹胀痛3个月。诊断：妇科普通慢性宫颈炎。取本发明实施例1制备得到的治疗妇科疾病的瑶药提取浓缩液，加入到温水(35℃-45℃)中，瑶药提取浓缩液与温水的体积比为1:20,洗浴20min-30min,每日1次。7天为一个疗程。1个疗程后，症状明显减轻；继续使用1个疗程，症状及体症均消失，治愈。随访1年未复发。
病例2：彭某，女，36岁，阴道骚痒，伴白带异味。诊断：霉菌性阴道炎、轻度宫颈糜烂。取本发明实施例2制备得到的治疗妇科疾病的瑶药提取浓缩液，加入到温水(35℃-45℃)中，瑶药提取浓缩液与温水的体积比为1:25,洗浴20min-30min,每日1次。7天为一个疗程。1个疗程后，症状明显减轻；继续使用1个疗程，症状及体症均消失，治愈。随访1年未复发。
病例3：邓某，女，38岁，白带增多引起霉菌性阴道炎。取本发明实施例3制备得到的治疗妇科疾病的瑶药提取浓缩液，加入到温水(35℃-45℃)中，瑶药提取浓缩液与温水的体积比为1:30,洗浴20min-30min,每日1次。7天为一个疗程。2个疗程后，症状及体症均消失，治愈。随访1年未复发。
以上所述仅为本发明的较佳实施例，并不用以限制本发明，凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (5)
1.一种治疗妇科疾病的瑶药提取浓缩液的制备方法，其特征在于，包括如下步骤：
步骤1：称取如下重量份数的原料：乌药8-12份、益母草8-12份、香附8-12份、川椒8-12份、大血藤8-12份、艾叶8-12份、生姜8-12份、山姜8-12份、香茅8-12份、柚叶8-12份、山鸡椒8-12份、黄皮树皮8-12份和茉莉花8-12份，分别粉碎后，混合，得到混合药材；
步骤2：将步骤1得到的混合药材加入到所述混合药材2-4倍重量的水中，浸泡3-5h后，再加入步骤1得到的混合药材4-6倍重量的水，提取1-3次，每次4h，合并提取液；
步骤3：将步骤2得到的提取液减压浓缩，得浸膏，罐装，灭菌，即得到治疗妇科疾病的瑶药提取浓缩液。
2.根据权利要求1所述治疗妇科疾病的瑶药提取浓缩液的制备方法，其特征在于，步骤1中，所述原料的重量份数为：乌药10份、益母草10份、香附10份、川椒10份、大血藤10份、艾叶10份、生姜10份、山姜10份、香茅10份、柚叶10份、山鸡椒10份、黄皮树皮10份和茉莉花10份。
3.根据权利要求1所述治疗妇科疾病的瑶药提取浓缩液的制备方法，其特征在于，步骤1中，所述粉碎的目数为10-20目。
4.根据权利要求1所述治疗妇科疾病的瑶药提取浓缩液的制备方法，其特征在于，步骤3中，所述浸膏在80℃时的相对密度为1.4。
5.根据权利要求1所述治疗妇科疾病的瑶药提取浓缩液的制备方法，其特征在于，步骤5中，所述灭菌为高压蒸汽灭菌，压力为(1.0-2.0)×105Pa，温度为100℃，时间为30-120min。
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