CN110689942A - Fishing net algorithm implementation method and device based on 3D accurate radiotherapy platform - Google Patents
Fishing net algorithm implementation method and device based on 3D accurate radiotherapy platform Download PDFInfo
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Abstract
The invention discloses a method for realizing a fishing net algorithm based on a 3D accurate radiotherapy platform, which comprises the following steps: A) loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform; B) automatically loading the CT.MR data beside a CTMR three-dimensional image; C) and performing union, correlation intersection and subtraction calculation on the CT.MR data by adopting a fishing net algorithm, so that a new shape is generated by combining basic graphs, and a 3D graph is finally formed. The invention also relates to a device for realizing the fishing net algorithm based on the 3D precise radiotherapy platform. The implementation method and the device of the fishing net algorithm based on the 3D precise radiotherapy platform have the following beneficial effects: the dependence degree of radiotherapy on doctor experience is reduced, the operation cost of a hospital is reduced, the stability in the radiotherapy process and the comfort of a patient are improved, and meanwhile, partial cost of the patient in radiotherapy is reduced.
Description
Technical Field
The invention relates to the field of medical auxiliary equipment, in particular to a method and a device for realizing a fishing net algorithm based on a 3D precise radiotherapy platform.
Background
After years of information-based construction and replacement of high-end medical instruments and other equipment in medical institutions, a plurality of problems of queuing, crowding, high working strength of doctors, doctor-patient relationship and the like of patients in the prior art are solved. While making great progress, there are also deficiencies in subdividing the field. For example, precise radiotherapy, the role and position of radiotherapy in tumor treatment are increasingly highlighted, and the radiotherapy is one of the main means for treating malignant tumors, but the radiotherapy faces the problem of difficult positioning. Because the position of the tumor is difficult to fix due to the influence of factors such as the position of the tumor, respiration and the like, the common radiotherapy is positioned by a simulation positioning machine, and the treatment range is marked on the skin of a patient by using skin ink. While killing tumor cells, the traditional or permanent damage of surrounding normal tissues or organs is brought, and some important organs are even damaged.
Disclosure of Invention
The technical problem to be solved by the invention is to provide a method and a device for realizing a fishing net algorithm based on a 3D precise radiotherapy platform, which can reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of a hospital, improve the stability and the comfort of a patient in the radiotherapy process and reduce partial cost of the patient in radiotherapy, aiming at the defects in the prior art.
The technical scheme adopted by the invention for solving the technical problems is as follows: a method for constructing a fishing net algorithm based on a 3D accurate radiotherapy platform comprises the following steps:
A) loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform;
B) automatically loading the CT.MR data beside a CTMR three-dimensional image;
C) and performing union, correlation intersection and subtraction calculation on the CT.MR data by adopting a fishing net algorithm, so that a new shape is generated by combining basic graphs, and a 3D graph is finally formed.
According to the implementation method of the fishing net algorithm based on the 3D precise radiotherapy platform, the 3D precise radiotherapy platform builds a front-end development frame through AngularJS, follows an MVC (model view controller) mode in architectural design, supports loose coupling of presentation, data and logic processing components, and achieves bidirectional automatic synchronization of a data model and a presentation view through a compiling technology.
In the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, the fishing net algorithm is a digital symbolic logic deduction algorithm, 16-20 ten thousand triangular planes are formed according to a 2-point-one-line triangular plane and a 3-point-one triangular plane, the datum point of a two-dimensional plane is obtained by taking CT.MR data as a core and a shadow plane as reference, and then the calculation of three-dimensional reconstruction is carried out.
In the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, and the Cut mode is Refine, Split, Remove index or Remove output.
In the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, the Refine can insert a contour line of an intersection region of the object B and the object A on the grid of the object A, and can create a selection region with any shape on the surface of the object without being limited by the grid; the Split can separate the intersection part of the operation into one element secondary object of the target object and continue to further edit the secondary object; deleting the intersecting part of the operation object by the Remove index, and creating a target object as a hollow object; the Remove Outside creates the intersection part of the operation object as a hollow object, and deletes the rest part.
The invention also relates to a device for realizing the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, which comprises the following steps:
a data loading and importing unit: the CT.MR data loading system is used for loading CT.MR data and importing the CT.MR data into a 3D precise radiotherapy platform;
an image loading unit: the CT.MR data are automatically loaded beside a CTMR three-dimensional image;
a calculation unit: and the CT.MR data are subjected to joint, correlation intersection and subtraction calculation by adopting a fishing net algorithm, so that a new shape is generated by combining basic graphs, and a 3D graph is finally formed.
In the device, the 3D precise radiotherapy platform builds a front-end development framework through AngularJS, follows an MVC (model view controller) mode in architectural design, supports loose coupling of presentation, data and logic processing components, and realizes bidirectional automatic synchronization of a data model and a presentation view through a compiling technology.
In the device, the fishing net algorithm is a digital symbolic logic deduction algorithm, 16-20 ten thousand triangular planes are formed according to a 2-point one-line and 3-point one triangular plane, the datum point of a two-dimensional plane is obtained by taking CT.MR data as a core and a shadow plane as reference, and then the calculation of three-dimensional reconstruction is carried out.
In the device, the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, and the Cut mode is Refine, Split, Remove index or Remove output.
In the device of the present invention, the Refine can insert a contour line of an intersection region of an object B and an object a on a mesh of the object a, and can create a selection region of any shape on the surface of the object without being limited by the mesh; the Split can separate the intersection part of the operation into one element secondary object of the target object and continue to further edit the secondary object; deleting the intersecting part of the operation object by the Remove index, and creating a target object as a hollow object; the Remove Outside creates the intersection part of the operation object as a hollow object, and deletes the rest part.
The implementation method and the device of the fishing net algorithm based on the 3D precise radiotherapy platform have the following beneficial effects: loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform; automatically loading CT.MR data beside the CTMR three-dimensional image; performing joint, correlation intersection and subtraction calculation on CT.MR data by adopting a fishing net algorithm, so that a basic graph is combined to generate a new shape, and a 3D graph is finally formed; the three-dimensional model is generated according to the actual data of the patient, the three-dimensional model can perfectly fit with the affected part of the patient, and the three-dimensional model has accurate body position fixing and three-dimensional positioning technology, so that the positioning precision, the positioning precision and the irradiation precision of radiotherapy can be improved, and therefore the three-dimensional model can reduce the dependence degree of the radiotherapy on doctor experience, reduce the operation cost of a hospital, improve the stability in the radiotherapy process and the comfort of the patient, and simultaneously reduce part of cost of the patient during radiotherapy.
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In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a flow chart of a method in an embodiment of a method and a device for realizing a fishing net algorithm based on a 3D precise radiotherapy platform according to the invention;
fig. 2 is a schematic structural diagram of the device in the embodiment.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the embodiment of the method and the device for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, a flow chart of the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform is shown in FIG. 1. In fig. 1, the method for implementing the fishing net algorithm based on the 3D precise radiotherapy platform includes the following steps:
step S01, loading ct.mr data, and importing it into a 3D precision radiotherapy platform: in the step, CT.MR data of a patient are loaded and are input into a 3D precise radiotherapy platform. The 3D precise radiotherapy platform is a self-developed brand-new software platform aiming at tumor radiotherapy, has a unique framework, and can realize precise radiotherapy. The 3D accurate radiotherapy platform uses a fishing net algorithm to perform 3D modeling, seamless butt joint of CT and MR data. This accurate radiotherapy platform of 3D utilizes the fishing net algorithm to handle the model, derives the model, carries out 3D to the model and prints. The dose delivered by the patient can be verified to achieve automatic optimization of the treatment plan.
This accurate radiotherapy platform of 3D builds front end development frame through angularJS, follow the MVC mode in the architectural design, advocate the presentation, the loose coupling of data and logic processing subassembly, realized natural extension to traditional HTML through the instruction technique, realize the two-way automatic synchronization of data model and presentation view through the compiling technique, thereby eliminate loaded down with trivial details complicated DOM operation in the front end development, contain the template, data two-way binding, the route, the modularization, service, the filter, rely on all functions such as injection into, self-defined Directive, it is still nimble than jQuery plug-in components. The background is compiled by adopting mature Java technology. The database used mysql.
The precise radiotherapy is a brand-new tumor radiotherapy technology which is precisely positioned, designed, calculated and executed on a therapy apparatus on the basis of conventional radiotherapy and integrates a three-dimensional image processing technology, a high-precision dose calculation algorithm, a top linear accelerator series technology, an advanced tumor diagnosis technology and a radiobiology frontier research result. Throughout the course of precision radiotherapy, each step emphasizes precision, which is a qualitative leap over conventional radiotherapy.
Step S02 automatically loads ct.mr data next to the CTMR three-dimensional image: in the step, the 3D precise radiotherapy platform automatically loads CT.MR data beside the CTMR three-dimensional image.
Step S03, the CT.MR data is combined, related intersection and subtraction calculated by adopting a fishing net algorithm, so that the basic graph combination generates a new shape, and a 3D graph is finally formed: in the step, the CT.MR data are subjected to joint, correlation intersection and subtraction calculation by adopting a fishing net algorithm, so that the basic graph combination generates a new shape, and a 3D graph is finally formed.
In the method for realizing the fishing net algorithm based on the 3D accurate radiotherapy platform, the fishing net algorithm is a digital symbolic logic deduction algorithm, 16-20 ten thousand triangular surfaces are formed according to 2 points and one line and 3 points with one triangular surface, the datum point of a two-dimensional plane is obtained by taking CT.MR data as a core and a shadow surface as a reference, and the calculation of three-dimensional reconstruction, including combination, correlation intersection and subtraction, is carried out, so that a new body is generated by combining simple basic graphs, and a 3D graph is finally formed.
The fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove output. Refine: in the method, the cutting fishing net operation can insert a contour line of the intersection area of the B object and the A object on the grid of the A object. By adopting the operation method, the selection area with any shape can be created on the surface of the object without the limitation of the grid. And (3) Split: in this way, the intersecting portion of the operation can be separated into one element sub-object of the target object, and further editing of the sub-object can continue. Remove Inde: the intersecting parts of the operation objects are deleted, and the target object is created as an empty object. Remove Outside: the intersection part of the operation object is created as a hollow object, and other parts are deleted.
The model is processed by utilizing a fishing net algorithm, a positioning film model (radiotherapy positioning film model), a compensator model, a headrest model (radiotherapy headrest model), a dose verification model (dose verification model) and the like can be prefabricated, and the models are integrated into a project model without manual design and modeling.
According to the method for realizing the fishing net algorithm based on the 3D accurate radiotherapy platform, the three-dimensional reconstruction is carried out according to the plane data through 3D printing of the positioning film model, the compensator model, the headrest model or the dose verification model, the part of the patient needing the operation is printed into the three-dimensional model in advance before the operation, and a doctor can visually see the structure of the operation part before the operation, particularly the operation on some complex parts, so that the operation risk can be avoided, and the success rate of the operation is greatly improved. The patient data is printed out according to the actual data of the patient, the patient is completely attached to the patient, and the traditional product cannot achieve the compensation effect due to the fact that the traditional product cannot be attached to the special patient part.
In the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, the 3D precise radiotherapy platform can be implanted by CT 3D scanning according to clinical patients, a three-dimensional model is derived by adopting a three-dimensional image processing technology, a high-precision dose calculation algorithm and a sharp linear accelerator series technology, then the model is subjected to contour design, direction button selection, adjustment and position setting by using the fishing net algorithm, a required model is finally generated, the processed model is derived, and the model is printed by using a 3D printer. 3D prints registration film, compensator, headrest or dose and verifies the die body, can perfectly agree with the patient affected part, has accurate position fixed and stereotaxic technique, can improve the positioning accuracy, the precision of putting and shine the precision of radiotherapy. The method for realizing the fishing net algorithm based on the 3D accurate radiotherapy platform can reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of a hospital, improve the stability in the radiotherapy process and the comfort of a patient, and reduce part of the cost of the patient during radiotherapy.
The invention also relates to a device for realizing the method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform, and the structural schematic diagram of the device is shown in figure 2. In fig. 2, the apparatus includes a data load import unit 1, an image load unit 2, and a calculation unit 3; the data loading and importing unit 1 is used for loading CT.MR data and importing the CT.MR data into a 3D precise radiotherapy platform.
The 3D precise radiotherapy platform is a self-developed brand-new software platform aiming at tumor radiotherapy, has a unique framework, and can realize precise radiotherapy. The 3D accurate radiotherapy platform uses a fishing net algorithm to perform 3D modeling, seamless butt joint of CT and MR data. This accurate radiotherapy platform of 3D utilizes the fishing net algorithm to handle the model, derives the model, carries out 3D to the model and prints. The dose delivered by the patient can be verified to achieve automatic optimization of the treatment plan.
This accurate radiotherapy platform of 3D builds front end development frame through angularJS, follow the MVC mode in the architectural design, advocate the presentation, the loose coupling of data and logic processing subassembly, realized natural extension to traditional HTML through the instruction technique, realize the two-way automatic synchronization of data model and presentation view through the compiling technique, thereby eliminate loaded down with trivial details complicated DOM operation in the front end development, contain the template, data two-way binding, the route, the modularization, service, the filter, rely on all functions such as injection into, self-defined Directive, it is still nimble than jQuery plug-in components. The background is compiled by adopting mature Java technology. The database used mysql.
The precise radiotherapy is a brand-new tumor radiotherapy technology which is precisely positioned, designed, calculated and executed on a therapy apparatus on the basis of conventional radiotherapy and integrates a three-dimensional image processing technology, a high-precision dose calculation algorithm, a top linear accelerator series technology, an advanced tumor diagnosis technology and a radiobiology frontier research result. Throughout the course of precision radiotherapy, each step emphasizes precision, which is a qualitative leap over conventional radiotherapy.
The image loading unit 2 is used for automatically loading the CT.MR data beside the CTMR three-dimensional image.
And the computing unit 3 is used for performing joint, correlation intersection and subtraction computation on the CT.MR data by adopting a fishing net algorithm, so that a new body is generated by combining the basic graphs, and a 3D graph is finally formed. In the method for realizing the fishing net algorithm based on the 3D accurate radiotherapy platform, the fishing net algorithm is a digital symbolic logic deduction algorithm, 16-20 ten thousand triangular surfaces are formed according to 2 points and one line and 3 points with one triangular surface, the datum point of a two-dimensional plane is obtained by taking CT.MR data as a core and a shadow surface as a reference, and the calculation of three-dimensional reconstruction, including combination, correlation intersection and subtraction, is carried out, so that a new body is generated by combining simple basic graphs, and a 3D graph is finally formed.
The fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove output. Refine: in the method, the cutting fishing net operation can insert a contour line of the intersection area of the B object and the A object on the grid of the A object. By adopting the operation method, the selection area with any shape can be created on the surface of the object without the limitation of the grid. And (3) Split: in this way, the intersecting portion of the operation can be separated into one element sub-object of the target object, and further editing of the sub-object can continue. Remove Inde: the intersecting parts of the operation objects are deleted, and the target object is created as an empty object. Remove Outside: the intersection part of the operation object is created as a hollow object, and other parts are deleted.
The model is processed by utilizing a fishing net algorithm, a positioning film model (radiotherapy positioning film model), a compensator model, a headrest model (radiotherapy headrest model), a dose verification model (dose verification model) and the like can be prefabricated, and the models are integrated into a project model without manual design and modeling.
In the device, the positioning film model, the compensator model, the headrest model or the dose verification model are printed in a 3D mode, three-dimensional reconstruction is carried out according to plane data, a three-dimensional model is printed on a part of a patient needing operation in advance before the operation, and a doctor can visually see the structure of the operation part before the operation, particularly the operation on some complex parts, so that the operation risk can be avoided, and the success rate of the operation is greatly improved. The patient data is printed out according to the actual data of the patient, the patient is completely attached to the patient, and the traditional product cannot achieve the compensation effect due to the fact that the traditional product cannot be attached to the special patient part.
In the device, a 3D accurate radiotherapy platform can be implanted by CT 3D scanning according to the introduction of a clinical patient, a three-dimensional model is derived by adopting a three-dimensional image processing technology, a high-precision dose calculation algorithm and a sharp linear accelerator series technology, then the model is subjected to contour design, direction button selection, adjustment and position setting by using a fishing net algorithm, a required model is finally generated, the processed model is derived, and a 3D printer is used for printing. 3D prints registration film, compensator, headrest or dose and verifies the die body, can perfectly agree with the patient affected part, has accurate position fixed and stereotaxic technique, can improve the positioning accuracy, the precision of putting and shine the precision of radiotherapy. The device of the invention can reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of hospitals, improve the stability in the radiotherapy process and the comfort of patients, and simultaneously reduce part of the cost of the patients during radiotherapy.
In a word, the invention applies the 3D printing technology to the medical auxiliary system of the precise radiotherapy of the tumor. The medical auxiliary equipment with pertinence can be provided according to different actual conditions of each patient, namely the positioning film, the compensator, the headrest or the dose verification die body, so that the dependence degree of radiotherapy on doctor experience is reduced, the operation cost of a hospital is reduced, the stability in the radiotherapy process and the comfort of the patient are improved, and meanwhile, partial cost of the patient during radiotherapy is reduced.
The medical industry has been the mainstream application field of 3D printing technology. The 3D printing technology has the characteristics of high flexibility, unlimited quantity, cost saving and the like, and can well meet the requirements of individual and precise medical treatment in the medical field. The 3D printing technology enables medical treatment to realize the crossing from virtual simulation to real simulation, and is an important means for realizing accurate radiotherapy of tumors. In the future, a biological 3D printer is matched with materials with biocompatibility and degradability to construct a biological scaffold, and a cell 3D printer or a biological 3D printer is used for selecting cells and biological materials to print out organisms. With continuous innovation of the 3D technology, the problem of difficulty in accurate tumor positioning can be solved by applying the 3D technology.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (10)
1. A method for realizing a fishing net algorithm based on a 3D accurate radiotherapy platform is characterized by comprising the following steps:
A) loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform;
B) automatically loading the CT.MR data beside a CTMR three-dimensional image;
C) and performing union, correlation intersection and subtraction calculation on the CT.MR data by adopting a fishing net algorithm, so that a new shape is generated by combining basic graphs, and a 3D graph is finally formed.
2. The method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform according to claim 1, wherein the 3D precise radiotherapy platform builds a front-end development framework through AngularJS, follows an MVC (model view controller) mode in architectural design, supports loose coupling of presentation, data and logic processing components, and realizes bidirectional automatic synchronization of a data model and a presentation view through a compiling technology.
3. The method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform according to claim 1 or 2, wherein the fishing net algorithm is a digital symbolic logic deduction algorithm, 16 to 20 ten thousand triangular planes are formed according to a 2-point-one-line triangular plane and a 3-point-one-triangular plane, the reference point of a two-dimensional plane is obtained by taking CT.MR data as a core and a shadow plane as a reference, and then the calculation of three-dimensional reconstruction is performed.
4. The method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform according to claim 3, wherein the fishing net algorithm is a Cut mode aiming at different conditions of patients, and the Cut mode is Refine, Split, Remove index or Remove output.
5. The method for realizing the fishing net algorithm based on the 3D precise radiotherapy platform according to claim 4, wherein the Refine can insert a contour line of an intersection region of the object B and the object A on the grid of the object A, and can create a selection region with any shape on the surface of the object without being limited by the grid; the Split can separate the intersection part of the operation into one element secondary object of the target object and continue to further edit the secondary object; deleting the intersecting part of the operation object by the Remove index, and creating a target object as a hollow object; the Remove Outside creates the intersection part of the operation object as a hollow object, and deletes the rest part.
6. An apparatus for implementing the method for implementing the fishing net algorithm based on the 3D precise radiotherapy platform according to claim 1, comprising:
a data loading and importing unit: the CT.MR data loading system is used for loading CT.MR data and importing the CT.MR data into a 3D precise radiotherapy platform;
an image loading unit: the CT.MR data are automatically loaded beside a CTMR three-dimensional image;
a calculation unit: and the CT.MR data are subjected to joint, correlation intersection and subtraction calculation by adopting a fishing net algorithm, so that a new shape is generated by combining basic graphs, and a 3D graph is finally formed.
7. The apparatus of claim 6, wherein the 3D precision radiotherapy platform builds a front-end development framework through AngularJS, follows MVC pattern in architectural design, supports loose coupling of presentation, data and logic processing components, and realizes bidirectional automatic synchronization of data model and presentation view through compiling technology.
8. The device according to claim 6 or 7, wherein the fishing net algorithm is a digital symbolic logic deduction algorithm, 16-20 ten thousand triangle planes are formed according to 2 points, one line and 3 points, one triangle plane, the datum point of a two-dimensional plane is obtained by taking CT.MR data as a core and a shadow plane as a reference, and then the calculation of three-dimensional reconstruction is carried out.
9. The device according to claim 8, wherein the fishing net algorithm is a Cut mode for different types of patients, and the Cut mode is Refine, Split, Remove index or Remove output.
10. The apparatus according to claim 9, wherein the Refine can insert a contour line of an intersection region of the object B and the object a on the mesh of the object a, and can create a selection region of any shape on the surface of the object without being limited by the mesh; the Split can separate the intersection part of the operation into one element secondary object of the target object and continue to further edit the secondary object; deleting the intersecting part of the operation object by the Remove index, and creating a target object as a hollow object; the Remove Outside creates the intersection part of the operation object as a hollow object, and deletes the rest part.
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