CN110624182A - 3D printing-based dose verification algorithm implementation method and device - Google Patents

3D printing-based dose verification algorithm implementation method and device Download PDF

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Publication number
CN110624182A
CN110624182A CN201910801464.5A CN201910801464A CN110624182A CN 110624182 A CN110624182 A CN 110624182A CN 201910801464 A CN201910801464 A CN 201910801464A CN 110624182 A CN110624182 A CN 110624182A
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Prior art keywords
dose
verification
algorithm
dose verification
verification algorithm
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刘芳
全世健
张宁
贾利柱
张振宇
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Guangzhou Putianyun Health Technology Development Co Ltd
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Guangzhou Putianyun Health Technology Development Co Ltd
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Priority to CN201910801464.5A priority Critical patent/CN110624182A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103Treatment planning systems
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/40ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1075Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
    • A61N2005/1076Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus using a dummy object placed in the radiation field, e.g. phantom

Abstract

The invention discloses a method for realizing a dose verification algorithm based on 3D printing, which comprises the following steps: A) loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform; B) determining an end point to be punched; C) selecting a measuring device; D) generating holes from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and the size of the measuring equipment; E) generating a punched dose verification algorithm model; F) deriving the punched dose verification algorithm model through the 3D accurate radiotherapy platform, and printing by adopting a 3D printer. The invention also relates to a device for realizing the method for realizing the dose verification algorithm based on the 3D printing. The invention can reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of hospitals, improve the stability in the radiotherapy process and the comfort of patients, and simultaneously reduce part of the cost of the patients during radiotherapy.

Description

3D printing-based dose verification algorithm implementation method and device
Technical Field
The invention relates to the field of 3D printing of medical auxiliary equipment, in particular to a method and a device for realizing a dose verification algorithm based on 3D printing.
Background
After years of information-based construction and replacement of high-end medical instruments and other equipment in medical institutions, a plurality of problems of queuing, crowding, high working strength of doctors, doctor-patient relationship and the like of patients in the prior art are solved. While making great progress, there are also deficiencies in subdividing the field. For example, precise radiotherapy, the role and position of radiotherapy in tumor treatment are increasingly highlighted, and the radiotherapy is one of the main means for treating malignant tumors, but the radiotherapy faces the problem of difficult positioning. Because the position of the tumor is difficult to fix due to the influence of factors such as the position of the tumor, respiration and the like, the common radiotherapy is positioned by a simulation positioning machine, and the treatment range is marked on the skin of a patient by using skin ink. While killing tumor cells, the traditional or permanent damage of surrounding normal tissues or organs is brought, and some important organs are even damaged.
Disclosure of Invention
The technical problem to be solved by the present invention is to provide a method and an apparatus for implementing a dose verification algorithm based on 3D printing, which can reduce the dependence of radiotherapy on doctor experience, reduce hospital operation cost, improve stability and patient comfort during radiotherapy, and reduce part of the cost of patients during radiotherapy.
The technical scheme adopted by the invention for solving the technical problems is as follows: a realization method of a dose verification algorithm based on 3D printing is constructed, and the method comprises the following steps:
A) loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform;
B) determining an end point to be punched;
C) selecting a measuring device;
D) generating holes from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and the size of the measuring equipment;
E) generating a punched dose verification algorithm model;
F) deriving the punched dose verification algorithm model through the 3D accurate radiotherapy platform, and printing by adopting a 3D printer.
In the method for realizing the dose verification algorithm based on 3D printing, the dose verification algorithm guides a designed plan into a die body for calculation to obtain the dose and the dose distribution in the die body; the phantom is substituted for the human, the patient is scheduled for execution at the accelerator, and the measured dose is compared to the computer-calculated dose.
In the implementation method of the dose verification algorithm based on 3D printing, the dose verification algorithm is divided into verification of absolute dose and verification of relative dose distribution, and the verification comprises point dose verification, two-dimensional plane dose verification, three-dimensional dose verification and third-party independent calculation software dose verification.
In the implementation method of the dose verification algorithm based on 3D printing, the verification of the absolute dose is performed on a point of interest by using a finger-shaped ionization chamber in the dose verification process of IMRT; the three-dimensional dose verification calculates the real three-dimensional dose distribution in the actual treatment of the patient body through a two-dimensional measuring tool, the ray fluence output by the accelerator is calculated through an algorithm, the ray fluence is combined with the individual form of the patient, and the dose algorithm.
In the method for realizing the dose verification algorithm based on 3D printing, in the step E), after the fishing net algorithm is adopted for processing, the punched dose verification algorithm model is generated; the processing of the fishing net algorithm comprises contour design, direction button selection, adjustment and position setting; the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove output.
The invention also relates to a device for realizing the method for realizing the dose verification algorithm based on the 3D printing, which comprises the following steps:
a data loading and importing unit: the CT.MR data loading system is used for loading CT.MR data and importing the CT.MR data into a 3D precise radiotherapy platform;
an end point determination unit: for determining an endpoint to punch;
measurement device selection unit: for selecting a measuring device;
a hole generation unit: the hole is used for generating a hole from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and the size of the measuring equipment;
a dose verification algorithm model generation unit: for generating a punched dose verification algorithm model;
a dose verification algorithm model derivation printing unit: and the 3D accurate radiotherapy platform is used for exporting the punched dose verification algorithm model, and a 3D printer is adopted for printing.
In the device, the dose verification algorithm guides a designed plan into the die body for calculation to obtain the dose and the dose distribution in the die body; the phantom is substituted for the human, the patient is scheduled for execution at the accelerator, and the measured dose is compared to the computer-calculated dose.
In the device of the present invention, the dose verification algorithm is divided into verification of absolute dose and verification of relative dose distribution, including point dose verification, two-dimensional plane dose verification, three-dimensional dose verification, and third-party independent calculation software dose verification.
In the device, the verification of the absolute dose is carried out on the point of interest by using a finger ionization chamber in the dose verification process of IMRT; the three-dimensional dose verification calculates the real three-dimensional dose distribution in the actual treatment of the patient body through a two-dimensional measuring tool, the ray fluence output by the accelerator is calculated through an algorithm, the ray fluence is combined with the individual form of the patient, and the dose algorithm.
In the device, the perforated dose verification algorithm model is generated after the dose verification algorithm model generating unit adopts fishing net algorithm processing; the processing of the fishing net algorithm comprises contour design, direction button selection, adjustment and position setting; the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove output.
The implementation method and the device for the dose verification algorithm based on 3D printing have the following beneficial effects: loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform; determining an end point to be punched; selecting a measuring device; generating holes from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and the size of the measuring equipment; generating a punched dose verification algorithm model; exporting a punched dose verification algorithm model through a 3D accurate radiotherapy platform, and printing by adopting a 3D printer; the invention can perfectly fit the affected part of the patient by printing according to the actual data of the patient, has accurate body position fixing and three-dimensional positioning technology, and can improve the positioning precision, the positioning precision and the irradiation precision of radiotherapy, thereby reducing the dependence degree of the radiotherapy on the experience of doctors, reducing the operation cost of hospitals, improving the stability in the radiotherapy process and the comfort of the patient, and simultaneously reducing partial cost of the patient during radiotherapy.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a flow chart of a method of an embodiment of a method and apparatus for implementing a 3D printing based dose verification algorithm according to the present invention;
fig. 2 is a schematic structural diagram of the device in the embodiment.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the embodiment of the method and the device for realizing the dose verification algorithm based on 3D printing, a flow chart of the method for realizing the dose verification algorithm based on 3D printing is shown in fig. 1. In fig. 1, the implementation method of the dose verification algorithm based on 3D printing includes the following steps:
step S01, loading ct.mr data, and importing it into a 3D precision radiotherapy platform: in the step, CT.MR data are loaded and imported into a 3D precise radiotherapy platform. The 3D precise radiotherapy platform is a self-developed brand-new software platform aiming at tumor radiotherapy, has a unique framework, and can realize precise radiotherapy. This accurate radiotherapy platform of 3D utilizes the fishing net algorithm to handle the model, derives the model, carries out 3D to the model and prints. The dose delivered by the patient can be verified to achieve automatic optimization of the treatment plan.
This accurate radiotherapy platform of 3D builds front end development frame through angularJS, follow the MVC mode in the architectural design, advocate the show, the loose coupling of data and logic processing subassembly, realized natural extension to traditional HTML through the instruction technique, two-way automatic synchronization of data model with the show view has been realized through compiling the technique, thereby loaded down with trivial details complicated DOM operation in the front end development has been eliminated, contain the template, data two-way binding, the route, the modularization, service, the filter, rely on all functions such as injection into, self-defined Directive, it is still nimble than jQuery plug-in components. The background is compiled by adopting mature Java technology. The database used mysql.
The precise radiotherapy is a brand-new tumor radiotherapy technology which is precisely positioned, designed, calculated and executed on a therapy apparatus on the basis of conventional radiotherapy and integrates a three-dimensional image processing technology, a high-precision dose calculation algorithm, a top linear accelerator series technology, an advanced tumor diagnosis technology and a radiobiology frontier research result. Throughout the course of precision radiotherapy, each step emphasizes precision, which is a qualitative leap over conventional radiotherapy.
Step S02 determines an end point to be punched: in this step, the physician determines the end point to be punched.
Step S03 selects a measurement device: in this step, a measurement device is selected.
Step S04 generates holes from the outermost surface of the dose verification algorithm model to the end of the punch according to the shape and size of the measuring device: in the step, holes from the outermost surface of the dose verification algorithm model to the punching end point are generated according to the shape and the size of the measuring equipment. Wherein, the dose verification algorithm model is generated by adopting a three-dimensional image processing technology, a high-precision dose calculation algorithm and a tip linear accelerator technology.
Step S06 generates a punched dose verification algorithm model: in the step, clicking treatment is carried out, and a perforated dose verification algorithm model is generated after fishing net algorithm treatment is adopted. The processing of the fishing net algorithm comprises contour design, direction button selection, adjustment and position setting.
Specifically, a dose verification algorithm model (three-dimensional model) is processed by adopting a fishing net algorithm, and the processing of the three-dimensional model comprises contour design, direction button selection, adjustment and position setting. The fishing net algorithm calculates the three dimensions formed by 16-20 ten thousand triangular surfaces, is a logic deduction algorithm of three points and one triangular surface, is a digital symbolic logic deduction algorithm, comprises combination, correlation intersection and subtraction, enables simple basic graph combinations to generate new shapes, and finally forms 3D graphs.
The fishing net algorithm adopts a Cut mode according to different situations of patients, wherein the Cut mode is Refine, Split, Remove index or Remove output. Refine: the clipping boolean operation in this way can insert a contour line of the intersection region of the B object and the a object on the mesh of the a object. By adopting the operation method, the selection area with any shape can be created on the surface of the object without the limitation of the grid. And (3) Split: in this way, the intersecting portion of the operation can be separated into one element sub-object of the target object, and further editing of the sub-object can continue. Remove Inde: the intersecting parts of the operation objects are deleted, and the target object is created as an empty object. Remove Outside: the intersection part of the operation object is created as a hollow object, and other parts are deleted. Step S06, deriving a punched dose verification algorithm model through a 3D accurate radiotherapy platform, and printing by adopting a 3D printer: in this step, derive the dose verification algorithm model that punches through the accurate radiotherapy platform of 3D, adopt the 3D printer to print, this 3D printer adopts the special printer of 3D medical treatment. The dose verification algorithm achieves automatic optimization of the treatment plan. A pre-fabricated perforated dose verification algorithm model can be integrated into the project model without manual design modeling. The 3D prints the punched dose verification algorithm model, carries out three-dimensional reconstruction according to plane data, prints out a three-dimensional model in advance of the part of the patient needing to be operated, and doctors can visually see the structure of the operated part before the operation, especially aiming at the operation of some complicated parts, so that the operation risk can be avoided, and the success rate of the operation is greatly improved. The patient data is printed out according to the actual data of the patient, the patient is completely attached to the patient, and the traditional product cannot achieve the compensation effect due to the fact that the traditional product cannot be attached to the special patient part. By validating the dose delivered by the patient, an automatic optimal optimization of the treatment plan is achieved.
In the method for realizing the dose verification algorithm based on 3D printing, a 3D precise radiotherapy platform is introduced into CT 3D scanning implantation according to a clinical patient, a three-dimensional model is derived by adopting a three-dimensional image processing technology, a high-precision dose calculation algorithm and a sharp linear accelerator series technology, then the three-dimensional model is subjected to contour design, direction button selection, adjustment and position setting by using a fishing net algorithm, a required model is finally generated, a punched dose verification algorithm model is derived, and printing is carried out by using a 3D printer. The 3D printing punched dose verification algorithm model can perfectly fit the affected part of a patient, has an accurate body position fixing and three-dimensional positioning technology, and can improve the positioning precision, the positioning precision and the irradiation precision of radiotherapy. The method for realizing the dose verification algorithm based on 3D printing can reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of a hospital, improve the stability in the radiotherapy process and the comfort of a patient, and reduce part of cost of the patient during radiotherapy.
The IMRT plan design is obtained by optimizing calculation according to a certain calculation method by utilizing a user accelerator data model through a reverse means; during the execution of the accelerator, the whole process of the radiation delivery is involved, and especially various parameters of the MLC, the stability of the output dose rate of the accelerator, etc. directly affect the accuracy of the target dose of the tumor of the patient, so corresponding dose verification must be performed.
The dose verification algorithm guides the designed plan into the die body for calculation to obtain the dose and the dose distribution in the die body; the phantom is substituted for the human, the patient is scheduled for execution at the accelerator, and the measured dose is compared to the computer-calculated dose. The dose verification algorithm is divided into verification of absolute dose and verification of relative dose distribution, and comprises point dose verification, two-dimensional plane dose verification, three-dimensional dose verification and third-party independent calculation software dose verification.
Verification of absolute dose: because the finger ionization chamber has the advantages of good stability in the aspects of dose linearity, energy response, repeatability and the like, the finger ionization chamber is used for verifying the absolute dose of a point of interest in the dose verification process of IMRT. Ionization chambers used clinically for IMRT absolute dose verification typically select small volumes to meet the measurement requirements of point dose, and the measurement points are selected in areas where the dose gradient is relatively flat to reduce dose measurement errors due to positional deviations.
Three-dimensional dose verification: the three-dimensional dose verification method is an intensity modulated radiotherapy dose verification method, and the ray fluence output by an accelerator is calculated by combining various algorithms through a two-dimensional measuring tool; the ray fluence is combined with the individual form of the patient, and the real three-dimensional dose distribution in the actual treatment of the patient is calculated through various dose algorithms so as to visually display various errors. The dose distribution in three dimensions is usually obtained by detectors distributed on the cylinder wall, a matrix of vertically crossing flat detectors, a rotating flat detector, etc. for verification.
The embodiment also relates to a device for implementing the method for implementing the dose verification algorithm based on 3D printing, and a schematic structural diagram of the device is shown in fig. 2. In fig. 2, the apparatus includes a data load importing unit 1, an end point determining unit 2, a measuring device selecting unit 3, a hole generating unit 4, a dose verification algorithm model generating unit 5, and a dose verification algorithm model export printing unit 6.
The data loading and importing unit 1 is used for loading CT.MR data and importing the CT.MR data into a 3D precise radiotherapy platform; an end point determining unit 2 for determining an end point to be punched; the measuring device selecting unit 3 is used for selecting a measuring device; the hole generation unit 4 is used for generating holes from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and size of the measuring equipment.
The dose verification algorithm model generation unit 5 is configured to generate a punched dose verification algorithm model. In the dose verification algorithm model generating unit 5, after the fishing net algorithm is adopted for processing, a punched dose verification algorithm model is generated; the processing of the fishing net algorithm comprises contour design, direction button selection, adjustment and position setting; the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove Outside.
The dose verification algorithm model export printing unit 6 is used for exporting the punched dose verification algorithm model through the 3D accurate radiotherapy platform, and a 3D printer is adopted for printing, and the 3D printer is a 3D medical special printer. The dose verification algorithm achieves automatic optimization of the treatment plan. A pre-fabricated perforated dose verification algorithm model can be integrated into the project model without manual design modeling. The 3D prints the punched dose verification algorithm model, carries out three-dimensional reconstruction according to plane data, prints out a three-dimensional model in advance of the part of the patient needing to be operated, and doctors can visually see the structure of the operated part before the operation, especially aiming at the operation of some complicated parts, so that the operation risk can be avoided, and the success rate of the operation is greatly improved. The patient data is printed out according to the actual data of the patient, the patient is completely attached to the patient, and the traditional product cannot achieve the compensation effect due to the fact that the traditional product cannot be attached to the special patient part. By validating the dose delivered by the patient, an automatic optimal optimization of the treatment plan is achieved.
In the device, a 3D accurate radiotherapy platform is used for leading in CT 3D scanning implantation according to a clinical patient, a three-dimensional model is led out by adopting a three-dimensional image processing technology, a high-precision dose calculation algorithm and a sharp linear accelerator series technology, then the three-dimensional model is subjected to contour design, direction button selection, adjustment and position setting by using a fishing net algorithm, a required model is finally generated, a punched dose verification algorithm model is led out, and printing is carried out by using a 3D printer. The 3D printing punched dose verification algorithm model can perfectly fit the affected part of a patient, has an accurate body position fixing and three-dimensional positioning technology, and can improve the positioning precision, the positioning precision and the irradiation precision of radiotherapy. The device of the invention can reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of hospitals, improve the stability in the radiotherapy process and the comfort of patients, and simultaneously reduce part of the cost of the patients during radiotherapy.
In a word, the invention applies the 3D printing technology to the medical auxiliary system of the precise radiotherapy of the tumor. The medical auxiliary equipment with pertinence, namely a dose verification algorithm, can be provided according to different actual conditions of each patient so as to reduce the dependence degree of radiotherapy on doctor experience, reduce the operation cost of a hospital, improve the stability in the radiotherapy process and the comfort of the patient and reduce partial cost of the patient during radiotherapy.
The medical industry has been the mainstream application field of 3D printing technology. The 3D printing technology has the characteristics of high flexibility, unlimited quantity, cost saving and the like, and can well meet the requirements of individual and precise medical treatment in the medical field. The 3D printing technology enables medical treatment to realize the crossing from virtual simulation to real simulation, and is an important means for realizing accurate radiotherapy of tumors. In the future, a biological 3D printer is matched with materials with biocompatibility and degradability to construct a biological scaffold, and a cell 3D printer or a biological 3D printer is used for selecting cells and biological materials to print out organisms. With continuous innovation of the 3D technology, the problem of difficulty in accurate tumor positioning can be solved by applying the 3D technology.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (10)

1. A method for realizing a dose verification algorithm based on 3D printing is characterized by comprising the following steps:
A) loading CT.MR data and importing the CT.MR data into a 3D accurate radiotherapy platform;
B) determining an end point to be punched;
C) selecting a measuring device;
D) generating holes from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and the size of the measuring equipment;
E) generating a punched dose verification algorithm model;
F) deriving the punched dose verification algorithm model through the 3D accurate radiotherapy platform, and printing by adopting a 3D printer.
2. The method for implementing a dose verification algorithm based on 3D printing according to claim 1, wherein the dose verification algorithm imports a designed plan onto a phantom for calculation to obtain a dose and a dose distribution in the phantom; the phantom is substituted for the human, the patient is scheduled for execution at the accelerator, and the measured dose is compared to the computer-calculated dose.
3. The method for implementing a 3D printing-based dose verification algorithm according to claim 2, wherein the dose verification algorithm is divided into verification of absolute dose and verification of relative dose distribution, including point dose verification, two-dimensional planar dose verification, three-dimensional dose verification, and third-party independent computing software dose verification.
4. The method of claim 3, wherein the verification of absolute dose is performed during dose verification of IMRT using a fingered ionization chamber for verification of absolute dose at a point of interest; the three-dimensional dose verification calculates the real three-dimensional dose distribution in the actual treatment of the patient body through a two-dimensional measuring tool, the ray fluence output by the accelerator is calculated through an algorithm, the ray fluence is combined with the individual form of the patient, and the dose algorithm.
5. The method for implementing a 3D printing-based dose verification algorithm according to any one of claims 1 to 4, wherein in the step E), after the fishing net algorithm is adopted for processing, the punched dose verification algorithm model is generated; the processing of the fishing net algorithm comprises contour design, direction button selection, adjustment and position setting; the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove Outside.
6. An apparatus for implementing the method of implementing a 3D printing based dose verification algorithm according to claim 1, comprising:
a data loading and importing unit: the CT.MR data loading system is used for loading CT.MR data and importing the CT.MR data into a 3D precise radiotherapy platform;
an end point determination unit: for determining an endpoint to punch;
measurement device selection unit: for selecting a measuring device;
a hole generation unit: the hole is used for generating a hole from the outermost surface of the dose verification algorithm model to the punching end point according to the shape and the size of the measuring equipment;
a dose verification algorithm model generation unit: for generating a punched dose verification algorithm model;
a dose verification algorithm model derivation printing unit: and the 3D accurate radiotherapy platform is used for exporting the punched dose verification algorithm model, and a 3D printer is adopted for printing.
7. The apparatus of claim 6, wherein the dose verification algorithm imports a designed plan onto the phantom for computation, resulting in dose and dose distribution in the phantom; the phantom is substituted for the human, the patient is scheduled for execution at the accelerator, and the measured dose is compared to the computer-calculated dose.
8. The device of claim 7, wherein the dose verification algorithm is divided into verification of absolute dose and verification of relative dose distribution, including point dose verification, two-dimensional planar dose verification, three-dimensional dose verification, and third-party independent computing software dose verification.
9. The apparatus of claim 8, wherein the verification of absolute dose is performed during dose verification of IMRT using a fingered ionization chamber for verification of absolute dose at a point of interest; the three-dimensional dose verification calculates the real three-dimensional dose distribution in the actual treatment of the patient body through a two-dimensional measuring tool, the ray fluence output by the accelerator is calculated through an algorithm, the ray fluence is combined with the individual form of the patient, and the dose algorithm.
10. The device according to any one of claims 6 to 9, wherein the dose verification algorithm model generating unit generates the punched dose verification algorithm model after processing by using a fishing net algorithm; the processing of the fishing net algorithm comprises contour design, direction button selection, adjustment and position setting; the fishing net algorithm adopts a Cut mode aiming at different conditions of patients, wherein the Cut mode is Refine, Split, Remove index or Remove output.
CN201910801464.5A 2019-08-28 2019-08-28 3D printing-based dose verification algorithm implementation method and device Pending CN110624182A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2977008A1 (en) * 2013-03-19 2016-01-27 Samsung Life Public Welfare Foundation Method, apparatus, and system for manufacturing phantom customized to patient
CN104888355A (en) * 2015-05-05 2015-09-09 倪昕晔 Verification method for ensuring accurate operation of intensity modulated radiation therapy
CN106228884A (en) * 2016-09-28 2016-12-14 湖北省肿瘤医院 A kind of individuation radiotherapy dosage checking anthropomorphic phantom
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Application publication date: 20191231