CN110680835A - Pilatory containing earthworm extract and preparation method thereof - Google Patents
Pilatory containing earthworm extract and preparation method thereof Download PDFInfo
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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Abstract
The invention belongs to the technical field of pilatory, and discloses a pilatory containing earthworm extract and a preparation method thereof, wherein the pilatory comprises the following raw materials in parts by weight: 50-100 parts of earthworm extracting solution, 40-80 parts of cinchona bark extracting solution, 30-60 parts of digitalis extracting solution, 20-40 parts of cordyceps sinensis extracting solution, 20-30 parts of platycladus orientalis extracting solution, 15-25 parts of glossy privet fruit extracting solution, 10-20 parts of ginseng extracting solution, 10-20 parts of ginkgo extracting solution, 5-10 parts of mint and 3-8 parts of lavender extracting solution. The hair restorer of the invention takes earthworm extract as a main raw material, is compounded with other traditional Chinese medicine materials, has the effects of nourishing blood, restoring hair, supplying balanced nutrition to scalp, improving physiological function, ensuring hair to obtain sufficient nutrients, restoring the function of hair follicle, absorbing the required nutrients, improving the function of scalp capillary vessels, promoting scalp blood circulation, preventing alopecia and promoting hair growth. It has the advantages of easily available raw materials, low cost, remarkable therapeutic effect, etc.
Description
Technical Field
The invention belongs to the technical field of pilatory, and relates to a pilatory containing earthworm extract and a preparation method thereof.
Background
The hair has the characteristics of growth, beauty, protection, elasticity and the like, plays an important role in instrument modification of people, is a basic condition for obtaining natural instrument beauty, and is also an index of the health condition of people. In recent years, with the development of society, the living environment is seriously polluted, the psychological stress is increased, and the attention of people on the self image is paid, so that the alopecia is more and more a disease troubled by modern urban people. A large number of researches are carried out on the pathogenesis and the pathogenesis of alopecia, the existing means for treating alopecia mainly comprise two types of traditional Chinese medicines and western medicines, and the traditional Chinese medicine considers that the alopecia is mostly caused by liver-kidney yin deficiency, blood deficiency and wind dryness and hair loss, and takes liver and kidney tonifying and blood circulation activating as the main method; the western medicine mostly adopts a single-component preparation or a simple medicinal preparation consisting of a plurality of components, such as finasteride, minoxidil and the like to prevent and treat alopecia. Although the types of products for treating alopecia in the current market are few, the actual use condition shows that the treatment effect is not ideal, and some products have long use period and slow effect; some treatments are not thorough; some medicines have some effects and do not need to be continuously used; some treatments are expensive; some are inconvenient to use, some have great toxic and side effects, and the like. In recent years, natural plants have been reported to prevent alopecia, but most of them are prepared from traditional Chinese herbal medicines, and it is difficult to obtain products with stable quality only from natural products such as plant extracts.
Chinese patent publication No. CN104435358 discloses a plant hair loss prevention and hair growth promoting liquid and a preparation method thereof, and discloses a plant hair loss prevention and hair growth promoting liquid which can improve head blood circulation, activate hair follicles, realize rapid hair loss prevention and repair and achieve the effect of treating both symptoms and root causes by utilizing the mutual synergistic effect of various traditional Chinese medicine components. However, it is administered by external application, and has poor therapeutic effect, and can not achieve the purpose of treating black hair and nourishing kidney.
Therefore, it is important to develop a safe and non-toxic hair restorer that can prevent hair loss and promote hair growth.
Disclosure of Invention
The invention aims to overcome the defects and provides a pilatory containing earthworm extract and a preparation method thereof.
In order to solve the technical problems, the technical scheme of the invention is as follows:
a pilatory containing earthworm extract comprises the following raw materials in parts by weight: 50-100 parts of earthworm extracting solution, 40-80 parts of cinchona bark extracting solution, 30-60 parts of digitalis extracting solution, 20-40 parts of cordyceps sinensis extracting solution, 20-30 parts of platycladus orientalis extracting solution, 15-25 parts of glossy privet fruit extracting solution, 10-20 parts of ginseng extracting solution, 10-20 parts of ginkgo extracting solution, 5-10 parts of mint and 3-8 parts of lavender extracting solution.
Preferably, the pilatory containing the earthworm extract comprises the following raw materials in parts by weight: 70-100 parts of earthworm extracting solution, 60-80 parts of cinchona bark extracting solution, 40-60 parts of digitalis extracting solution, 30-40 parts of cordyceps sinensis extracting solution, 25-30 parts of platycladus orientalis extracting solution, 20-25 parts of glossy privet fruit extracting solution, 15-20 parts of ginseng extracting solution, 10-15 parts of ginkgo extracting solution, 6-10 parts of mint and 5-8 parts of lavender extracting solution.
Preferably, the pilatory containing the earthworm extract comprises the following raw materials in parts by weight: 80 parts of earthworm extracting solution, 70 parts of cinchona bark extracting solution, 50 parts of digitalis extracting solution, 35 parts of cordyceps sinensis extracting solution, 25 parts of platycladus orientalis extracting solution, 20 parts of glossy privet fruit extracting solution, 15 parts of ginseng extracting solution, 12 parts of ginkgo extracting solution, 8 parts of mint and 6 parts of lavender extracting solution.
Preferably, the hair restorer also comprises the following raw materials in parts by weight: 10-20 parts of black sesame and 10-20 parts of saponin.
The invention also aims to provide a preparation method of the pilatory containing the earthworm extract, which comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 1-3 times of water, soaking for 50-120min, and filtering to obtain a first filtrate and filter residues; adding 8-15 times of ethanol into the filter residue, leaching for 30-60h, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 10-20min, decocting for 30-50min, filtering, further decocting with 5-10 times of ultrapure water for 10-20min, filtering, and mixing the two filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
Preferably, the volume concentration of the ethanol in the step (2) is 80-95%.
Preferably, the ethanol leaching temperature in the step (2) is 45-65 ℃.
Compared with the prior art, the invention has the beneficial effects that:
(1) the hair restorer of the invention takes earthworm extract as a main raw material, is compounded with other traditional Chinese medicine materials, has the effects of nourishing blood, restoring hair, supplying balanced nutrition to scalp, improving physiological function, ensuring hair to obtain sufficient nutrients, restoring the function of hair follicle, absorbing the required nutrients, improving the function of scalp capillary vessels, promoting scalp blood circulation, preventing alopecia and promoting hair growth. It has the advantages of easily available raw materials, low cost, remarkable therapeutic effect, etc.
(2) The traditional Chinese medicinal materials contained in the hair restorer in the formula, such as cinchona bark, digitalis, cordyceps sinensis, platycladus orientalis, ligustrum lucidum ait, ginseng and ginkgo, have the effects of growing and blackening hair and nourishing and protecting hair, and simultaneously have the effect of promoting blood circulation, thereby being beneficial to scalp hair follicle restoration and accelerating the hair growth speed.
(3) The hair restorer starts from the root of the hair loss and hair growth problem, specifically solves various factors causing the hair loss and hair growth problem, realizes the comprehensive treatment of the hair loss from the root, effectively improves the curative effect of the hair loss and hair growth, and has various efficacies of nourishing yin and tonifying kidney, relieving mood, nourishing and blackening hair, building body and the like. Compared with the existing pilatory which aims at repairing the hair follicles of the epidermis, has poor fundamental treatment effect on the alopecia, single treatment effect and temporary solution but not permanent solution, the pilatory which mainly treats the permanent solution and treats both principal and secondary aspects of diseases and is safe and reliable is provided.
Detailed Description
The following further describes the embodiments of the present invention. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. In addition, the technical features involved in the embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
Example 1
A pilatory containing earthworm extract comprises the following raw materials in parts by weight: 50 parts of earthworm extracting solution, 40 parts of cinchona bark extracting solution, 30 parts of digitalis extracting solution, 20 parts of cordyceps sinensis extracting solution, 20 parts of platycladus orientalis extracting solution, 15 parts of glossy privet fruit extracting solution, 10 parts of ginseng extracting solution, 10 parts of ginkgo extracting solution, 5 parts of mint and 3 parts of lavender extracting solution.
A preparation method of a pilatory containing earthworm extract comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 1 time of water, soaking for 120min, and filtering to obtain a first filtrate and filter residue; then adding ethanol with the volume concentration of 80 percent, which is 8 times that of the raw material, into the filter residue, leaching for 60 hours at the temperature of 45 ℃, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 10min, decocting for 50min, filtering, further decocting with 5 times of ultrapure water for 10min, filtering, and mixing the two filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
Example 2
A pilatory containing earthworm extract comprises the following raw materials in parts by weight: 100 parts of earthworm extracting solution, 80 parts of cinchona bark extracting solution, 60 parts of digitalis extracting solution, 40 parts of cordyceps sinensis extracting solution, 30 parts of platycladus orientalis extracting solution, 25 parts of glossy privet fruit extracting solution, 20 parts of ginseng extracting solution, 20 parts of ginkgo extracting solution, 10 parts of mint and 8 parts of lavender extracting solution.
A preparation method of a pilatory containing earthworm extract comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 2 times of water, soaking for 80min, and filtering to obtain a first filtrate and filter residues; then adding ethanol with the volume concentration of 85 percent, which is 10 times that of the raw materials, into the filter residue, leaching for 50 hours at 50 ℃, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 15min, decocting for 40min, filtering, further decocting with 8 times of ultrapure water for 15min, filtering, and mixing the two filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
Example 3
A pilatory containing earthworm extract comprises the following raw materials in parts by weight: 80 parts of earthworm extracting solution, 70 parts of cinchona bark extracting solution, 50 parts of digitalis extracting solution, 35 parts of cordyceps sinensis extracting solution, 25 parts of platycladus orientalis extracting solution, 20 parts of glossy privet fruit extracting solution, 15 parts of ginseng extracting solution, 12 parts of ginkgo extracting solution, 8 parts of mint and 6 parts of lavender extracting solution.
A preparation method of a pilatory containing earthworm extract comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 3 times of water for soaking for 60min, and filtering to obtain a first filtrate and filter residues; then adding ethanol with the volume concentration of 90 percent which is 12 times that of the raw material into the filter residue, leaching for 40 hours at the temperature of 60 ℃, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 18min, decocting for 35min, filtering, further decocting with 6 times of ultrapure water for 12min, filtering, and mixing the filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
Example 4
A pilatory containing earthworm extract comprises the following raw materials in parts by weight: 70 parts of earthworm extracting solution, 60 parts of cinchona bark extracting solution, 40 parts of digitalis extracting solution, 30 parts of cordyceps sinensis extracting solution, 25 parts of platycladus orientalis extracting solution, 20 parts of glossy privet fruit extracting solution, 15 parts of ginseng extracting solution, 10 parts of ginkgo extracting solution, 6 parts of mint and 5 parts of lavender extracting solution.
A preparation method of a pilatory containing earthworm extract comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 2 times of water, soaking for 100min, and filtering to obtain a first filtrate and filter residues; then adding ethanol with the volume concentration of 95 percent, which is 10 times that of the raw materials, into the filter residue, leaching for 30 hours at 65 ℃, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 20min, decocting for 30min, filtering, further decocting with 10 times of ultrapure water for 10min, filtering, and mixing the two filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
Example 5
A pilatory containing earthworm extract comprises the following raw materials in parts by weight: 100 parts of earthworm extracting solution, 80 parts of cinchona bark extracting solution, 60 parts of digitalis extracting solution, 40 parts of cordyceps sinensis extracting solution, 30 parts of platycladus orientalis extracting solution, 25 parts of glossy privet fruit extracting solution, 20 parts of ginseng extracting solution, 15 parts of ginkgo extracting solution, 10 parts of mint and 8 parts of lavender extracting solution.
A preparation method of a pilatory containing earthworm extract comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 3 times of water, soaking for 50min, and filtering to obtain a first filtrate and filter residues; adding ethanol with volume concentration of 95% 15 times of the raw materials into the filter residue, leaching for 30h at 65 ℃, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 20min, decocting for 50min, filtering, further decocting with 10 times of ultrapure water for 10min, filtering, and mixing the two filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
Examples of the applications
(1) Plum, male, 36 years old, intellectual property workers, long-term brain use, stay up overnight and shift overtime, the working pressure is high, and the top alopecia begins four years ago until the alopecia is formed; after 90 days using the hair restorer prepared in example 3 of the present invention, the hair began to grow, and after 6 months, full and black hair was formed and the hair was rarely separated.
(2) Sun female, age 30, company clerk, postpartum alopecia, depressed mood, weak constitution, insomnia, dreaminess, severe hair loss, and sparse yellow hair. After using the hair restorer prepared in example 3 of the present invention, the hair was stopped falling after 1 month, and after careful observation, new hairs like fine hair were seen, short hairs began to grow after 3 months, long hairs covered the whole scalp after 5 months, and the grown hairs were black.
(3) Mr. Zhou, age 45, high pipe, often need accompany customers to eat and drink wine, and need work overtime for a long time, the rhythm of life is fast, pressure is big, begin to continue alopecia two years ago, the scalp is dry and itchy, the alopecia condition is serious gradually, hair top and forehead basically take off the light. After the hair restorer prepared in the embodiment 3 of the invention is used, the head stops itching after 10 days, the hair starts to grow after 1 month, the mood state is improved, the hair grows gradually thick after 2 months, the hair loss problem is basically avoided after 4 months, and the hair grows dark and thick.
The foregoing is considered as illustrative of the preferred embodiments of the invention, but is made merely for the purpose of providing an understanding of the principles of the embodiments; meanwhile, for a person skilled in the art, according to the present embodiment, there may be a change in the specific implementation and application scope, and in summary, the present disclosure should not be construed as a limitation to the present invention.
Claims (7)
1. A pilatory containing earthworm extract is characterized in that: the feed comprises the following raw materials in parts by weight: 50-100 parts of earthworm extracting solution, 40-80 parts of cinchona bark extracting solution, 30-60 parts of digitalis extracting solution, 20-40 parts of cordyceps sinensis extracting solution, 20-30 parts of platycladus orientalis extracting solution, 15-25 parts of glossy privet fruit extracting solution, 10-20 parts of ginseng extracting solution, 10-20 parts of ginkgo extracting solution, 5-10 parts of mint and 3-8 parts of lavender extracting solution.
2. The hair tonic containing the earthworm extract according to claim 1, which is characterized in that: the feed comprises the following raw materials in parts by weight: 70-100 parts of earthworm extracting solution, 60-80 parts of cinchona bark extracting solution, 40-60 parts of digitalis extracting solution, 30-40 parts of cordyceps sinensis extracting solution, 25-30 parts of platycladus orientalis extracting solution, 20-25 parts of glossy privet fruit extracting solution, 15-20 parts of ginseng extracting solution, 10-15 parts of ginkgo extracting solution, 6-10 parts of mint and 5-8 parts of lavender extracting solution.
3. The hair tonic containing the earthworm extract according to claim 1, which is characterized in that: the feed comprises the following raw materials in parts by weight: 80 parts of earthworm extracting solution, 70 parts of cinchona bark extracting solution, 50 parts of digitalis extracting solution, 35 parts of cordyceps sinensis extracting solution, 25 parts of platycladus orientalis extracting solution, 20 parts of glossy privet fruit extracting solution, 15 parts of ginseng extracting solution, 12 parts of ginkgo extracting solution, 8 parts of mint and 6 parts of lavender extracting solution.
4. The hair tonic containing the earthworm extract according to claim 1, which is characterized in that: the hair restorer also comprises the following raw materials in parts by weight: 10-20 parts of black sesame and 10-20 parts of saponin.
5. A method for preparing the hair tonic containing the earthworm extract according to claim 1, which comprises: the method comprises the following steps:
(1) weighing dry medicinal materials of cortex cinchonii, digitalis, cordyceps sinensis, platycladus orientalis, glossy privet fruit, ginseng and ginkgo in parts by weight, removing impurities, decontaminating, removing dust, and then carrying out superfine grinding to obtain a crushed traditional Chinese medicine raw material;
(2) adding the crushed traditional Chinese medicine raw materials obtained in the step (1) into 1-3 times of water, soaking for 50-120min, and filtering to obtain a first filtrate and filter residues; adding 8-15 times of ethanol into the filter residue, leaching for 30-60h, and filtering to obtain a second filtrate; the first step is carried out; mixing the filtrate with the second filtrate, decolorizing with activated carbon, and filtering to obtain Chinese medicinal extractive solution;
(3) cutting Lumbricus, soaking in ultrapure water for 10-20min, decocting for 30-50min, filtering, further decocting with 5-10 times of ultrapure water for 10-20min, filtering, and mixing the two filtrates to obtain Lumbricus extractive solution;
(4) and (3) mixing the traditional Chinese medicine extracting solution obtained in the step (2) and the earthworm extracting solution obtained in the step (3), performing rotary evaporation to obtain a concentrated solution, adding absolute ethyl alcohol with one third of the total volume of the concentrated solution, and uniformly mixing to obtain the pilatory containing the earthworm extracting solution.
6. The method for producing a hair tonic containing an earthworm extract according to claim 1, comprising: the volume concentration of the ethanol in the step (2) is 80-95%.
7. The method for producing a hair tonic containing an earthworm extract according to claim 1, comprising: the ethanol leaching temperature in the step (2) is 45-65 ℃.
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CN102046183A (en) * | 2008-06-17 | 2011-05-04 | 伊莱亚斯·布拉斯 | Compositions for the treatment of hair loss |
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CN108853480A (en) * | 2018-07-31 | 2018-11-23 | 黑龙江省中医药科学院 | Hair growth composition, preparation method and applications |
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CN102046183A (en) * | 2008-06-17 | 2011-05-04 | 伊莱亚斯·布拉斯 | Compositions for the treatment of hair loss |
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