CN110663680A - Machine of confession kidney fills to preserve and transports instrument - Google Patents
Machine of confession kidney fills to preserve and transports instrument Download PDFInfo
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- CN110663680A CN110663680A CN201911025470.2A CN201911025470A CN110663680A CN 110663680 A CN110663680 A CN 110663680A CN 201911025470 A CN201911025470 A CN 201911025470A CN 110663680 A CN110663680 A CN 110663680A
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- 210000003734 kidney Anatomy 0.000 title claims abstract description 145
- 230000032258 transport Effects 0.000 title description 8
- 230000010412 perfusion Effects 0.000 claims abstract description 69
- 239000007788 liquid Substances 0.000 claims abstract description 62
- 238000004321 preservation Methods 0.000 claims abstract description 35
- 238000012546 transfer Methods 0.000 claims abstract description 16
- 210000001367 artery Anatomy 0.000 claims abstract description 11
- 239000012530 fluid Substances 0.000 claims abstract description 7
- 238000007789 sealing Methods 0.000 claims description 19
- 238000003860 storage Methods 0.000 claims description 11
- 238000001914 filtration Methods 0.000 claims description 7
- 239000004033 plastic Substances 0.000 claims description 6
- 229920003023 plastic Polymers 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 5
- 239000004816 latex Substances 0.000 claims description 3
- 229920000126 latex Polymers 0.000 claims description 3
- 239000007769 metal material Substances 0.000 claims description 3
- 231100000252 nontoxic Toxicity 0.000 claims description 3
- 230000003000 nontoxic effect Effects 0.000 claims description 3
- 230000005540 biological transmission Effects 0.000 claims description 2
- 238000013461 design Methods 0.000 description 18
- 230000000694 effects Effects 0.000 description 12
- 210000004204 blood vessel Anatomy 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 230000004087 circulation Effects 0.000 description 9
- 230000008569 process Effects 0.000 description 8
- 239000008280 blood Substances 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 7
- 210000000056 organ Anatomy 0.000 description 6
- 210000002254 renal artery Anatomy 0.000 description 6
- 210000003462 vein Anatomy 0.000 description 6
- 239000003761 preservation solution Substances 0.000 description 5
- 238000012545 processing Methods 0.000 description 4
- 238000002054 transplantation Methods 0.000 description 4
- 210000000577 adipose tissue Anatomy 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 238000004140 cleaning Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000005086 pumping Methods 0.000 description 3
- 230000000087 stabilizing effect Effects 0.000 description 3
- 238000007792 addition Methods 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000008081 blood perfusion Effects 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 208000028208 end stage renal disease Diseases 0.000 description 1
- 201000000523 end stage renal failure Diseases 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 210000002796 renal vein Anatomy 0.000 description 1
- 238000005096 rolling process Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
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- Health & Medical Sciences (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
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Abstract
The invention relates to a machine perfusion preservation and transfer instrument for kidneys, which comprises a shell, a kidney cylinder, a pump body, a connecting pipe, a pump body fixing frame and a kidney rack, wherein the shell is fixedly connected with the kidney cylinder; an ice bag can be filled between the shell and the kidney jar; the kidney jar can be internally provided with preserving fluid; the pump body comprises a liquid inlet, a liquid outlet, fan blades, a sensor, a Bluetooth control system, a central controller, a power supply and a power device; the liquid inlet is arranged at the center of the bottom of the pump body; the liquid outlet is arranged in the right middle of the pump body; the liquid outlet is fixedly connected with the connecting pipe; the sensor is arranged at the joint of the pump body liquid outlet and the connecting pipe; the Bluetooth control system is arranged in the central controller; the pump body fixing frame and the kidney are arranged at the bottom of the kidney cylinder; the pump body is fixedly connected with the artery blood vessel on the transplanted kidney by using a connecting pipe. Its advantages are: the volume is small, the price is low, the carrying is convenient, and the working state of the instrument can be displayed or controlled in real time.
Description
Technical Field
The invention relates to the technical field of machine perfusion, in particular to a machine perfusion preservation and transfer instrument for kidneys.
Background
Kidney transplantation is an effective means for treating end-stage renal disease, and preservation techniques for transplanted kidneys have been developed along with kidney transplantation. Lifeport is used widely as a mechanical perfusion instrument for transplanting kidney. The Lifeport mainly comprises 1 insulated main shell, a control panel, an external display screen, an ice storage box, a pump deck, a sensor, electronic elements and partial disposable consumables. The control panel can be used for selecting the operation mode and setting the perfusion parameters. The outer display screen is provided with 4 displays which respectively provide information of pressure, flow velocity, vascular resistance and temperature, and is additionally provided with 1 two-line rolling caption for displaying the perfusion condition in real time. In short, Life port has gained much acceptance from transplantation centers due to its ease of operation, stability, and full automation.
However, the conventional Lifeport used in hospitals at present is similar to an oval structure, the length is about 80cm, the volume is large, and the carrying is inconvenient. In addition, Lifeport is expensive because of its use as a mechanical perfusion apparatus for kidney transplantation, and one machine needs 30 ten thousand RMB, while one set of consumables (intelligent lavage of one kidney) needs 2.5 ten thousand RMB, which is hard to bear for ordinary hospitals or medical centers.
Chinese patent documents: CN201810142787.3, application date 2018.02.11, patent names: a multi-organ integrated perfusion device. The utility model discloses an integrative perfusion equipment of many organs, including main frame, control system and a plurality of pipeline circulation system, a plurality of pipeline circulation system are communication connection controlling means respectively, and every pipeline circulation system all includes: the centrifugal blood pump is in communication connection with the control system; an inlet end pipeline of the oxygenator is connected with an outlet end of the centrifugal blood pump; the inlet end pipeline of the filter is connected with the outlet end of the oxygenator; a plurality of organ placing containers, wherein the inlet end of each organ placing container is respectively connected with the outlet end of the filter through a pipeline, and the outlet end of each organ placing container is respectively connected with the inlet end of the centrifugal blood pump through a pipeline; a flow control valve is arranged between the organ container and the filter.
Chinese patent documents: CN201910105499.5, application date 2019.02.01, patent names: a kidney perfusion device. The kidney vein circulation switching module is used for connecting a donor kidney vein and a vein connecting end of a normal temperature perfusion module so as to drain venous blood of the donor kidney vein into the normal temperature perfusion module; the renal artery circulation switching module is used for connecting the donor renal artery and the artery connecting end of the normal-temperature perfusion module so as to drain arterial blood output by the normal-temperature perfusion module back to the donor renal artery; the first filter, the first oxygen combiner and the first centrifugal pump are sequentially communicated through a first pipeline, the first filter is used for being communicated with a donor vein, and the first centrifugal pump is used for being communicated with a donor artery; the first liquid adding device is used for being communicated with a donor artery and supplementing perfusate to the donor artery when the renal vein circulation switching module drains venous blood; the normal temperature perfusion module is used for perfusion of the kidney.
In the above patent document CN201810142787.3, a control system can control a plurality of pipeline circulation systems simultaneously, so that devices such as centrifugal blood pumps in different pipeline circulation systems can be controlled to be in different working states according to the needs of different isolated organs; in addition, in the kidney perfusion device disclosed in patent document CN201910105499.5, the risk of PNF and DGF is reduced by using body-worn blood perfusion instead of cold perfusion for preservation to prevent secondary damage caused by the freezing fluid. However, there is no report on a kidney perfusion preservation and transportation apparatus that is small in size, low in price, convenient to carry, and capable of displaying or controlling the working state of the apparatus in real time.
In view of the above, there is a need for a kidney perfusion storage and transportation apparatus that is small in size, low in cost, portable, and capable of displaying or controlling the working state of the apparatus in real time.
Disclosure of Invention
The invention aims to provide a machine perfusion storage and transfer instrument for kidneys, which has small volume, low price and convenient carrying and can display or control the working state of the instrument in real time, aiming at the defects in the prior art.
In order to achieve the purpose, the invention adopts the technical scheme that:
a machine perfusion preservation and transfer instrument for kidneys is characterized by comprising a shell, a kidney cylinder, a pump body, a connecting pipe, a pump body fixing frame and a kidney frame; the shell is of a concave structure, the inner wall of the shell is of a hollow structure, handles are arranged on two sides of the shell, and a cover body is arranged at the top of the shell; the kidney jar is also of a concave structure, and the top of the kidney jar is provided with a sealing cover; the kidney jar can be internally provided with preserving fluid; the kidney jar is arranged in the shell, and ice bags can be filled between the kidney jar and the two sides and the bottom of the shell; the pump body comprises a liquid inlet, a liquid outlet, fan blades, a sensor, a Bluetooth control system, a central controller, a power supply and a power device; the liquid inlet is arranged at the center of the bottom of the pump body, and the front end of the liquid inlet is provided with a filtering device; the liquid outlet is arranged in the right middle of the pump body; the fan blades are arranged in the pump body; the liquid outlet is fixedly connected with the connecting pipe; the periphery of the tail end of the connecting pipe can be provided with an air bag and a telescopic ring; the sensor is arranged at the joint of the pump body liquid outlet and the connecting pipe; the Bluetooth control system is arranged in the central controller; the central controller, the power supply and the power device are respectively arranged above the interior of the pump body; the central controller can be connected with external equipment through a Bluetooth control system; the pump body fixing frame and the kidney are arranged at the bottom of the kidney cylinder; an opening is formed in the middle of the surface of the pump body fixing frame; the pump body is fixedly connected with the artery blood vessel on the transplanted kidney by using a connecting pipe.
As a preferred technical scheme, the fan blades are of a pulse type rotating structure.
As a preferred technical scheme, the filtering device is a filter screen.
As a preferred technical scheme, the surfaces of the cover body and the sealing cover are both provided with handles.
As a preferred technical solution, the external device is app software at a mobile phone end or a computer end.
As a preferred technical scheme, the fan blades, the sensor, the central controller and the power supply are in a wireless transmission connection mode, and the power supply can be charged in a wired or wireless mode.
As a preferable technical scheme, a sealing strip is arranged between the periphery of the sealing cover and the periphery of the top of the renal jar.
As a preferred technical scheme, the shell is made of a non-toxic, low-temperature-resistant and high-temperature-resistant sterile plastic material.
As a preferred technical scheme, the kidney jar is made of metal materials.
As a preferred technical scheme, the air bag and the telescopic ring are made of plastics or latex materials.
The invention has the advantages that:
1. the design of filling the ice bag between the kidney jar and the shell can keep the temperature of the preservation solution at 0-4 ℃, thereby keeping the normal physiological characteristics of the transplanted kidney.
2. The design of the concave structure in the kidney jar can make the kidney jar closely fit with the inner space of the shell, thereby preventing the kidney jar from overturning while keeping the temperature range of the internal storage liquid of the kidney jar.
3. The handles arranged on the two sides of the shell are of movable structures with the shell, and the instrument body is conveniently and directly lifted and taken by a single person through the design of the handles, so that the instrument is convenient to carry.
4. The pump body is connected with the artery blood vessel on the transplanted kidney through a connecting pipe, so that the circulating perfusion preservation effect inside the kidney can be realized.
5. The connecting pipe and the transplanted renal artery blood vessel are connected in a mode that the internal and external acting forces are mutually abutted, so that the effect of sealing and fixing can be ensured.
6. When the fan blade works, the fan blade is in a pulse type rotating structure, so that the blood flow can be simulated to be pumped into the transplanted kidney, and the functions of perfusion, cleaning and preservation can be performed.
7. Through locating central controller and power in the inside independent spaced design in top of the pump body, can guarantee the normal operating condition of central controller and power, avoid contacting and preserve behind the liquid and malfunctioning problem.
8. The instruction of the central processing unit can be controlled through external equipment, so that the work and stop of the pump body can be freely controlled, the rotating speed of the fan blades can be controlled, and the use is convenient.
9. When the fan blades in the pump body operate, the preservation liquid in the kidney jar enters the pump body through the liquid inlet of the pump body, then flows into the connecting pipe through the liquid outlet, finally enters the transplanted kidney through the arterial blood vessel, and then flows out of the venous blood vessel into the kidney jar, so that the perfusion effect of the circulation machine for transplanting the kidney is realized.
10. The design of pump body below is located to the inlet, can keep the inlet to arrange in and preserve liquid all the time to avoid appearing the pump income gaseous condition, in addition, locate the filter equipment of inlet front end and can avoid transplanting in the kidney objects such as exhaust adipose tissue and enter into to transplanting in the kidney by the inlet, thereby guarantee to fill the effect.
11. The sensor arranged at the joint of the liquid outlet and the connecting pipe can transmit data such as temperature, resistance, flow rate and the like of the storage liquid in the transplanted kidney to the central controller, and the external equipment can monitor the machine perfusion condition in real time by receiving the data from the central controller, so that the safety of the perfusion process is ensured.
12. The filling time of the machine and the normal range of each data can be set through the external equipment, the pump body automatically stops filling when the set time is reached, and when the monitored data is not in the normal range, the automatic alarm can be given, so that the filling safety of the machine is ensured.
13. Locate the pump body mount and the kidney frame of kidney jar bottom and be used for stabilizing the pump body and transplant the kidney, avoid in the in-process of pouring into, lead to the pump body or transplant the kidney upset because the pump body shakes or preserves liquid flow etc..
14. Compared with the existing Life port perfusion instrument, the volume of the kidney perfusion storage and transfer instrument is reduced to be of an inward concave structure, and all data in the perfusion process are transmitted to external equipment, so that the design of a display screen and other electronic elements is reduced, the transportation and carrying are convenient, and the manufacturing cost of the instrument is reduced.
Drawings
FIG. 1 is a schematic plan view of a kidney perfusion preserving and transporting apparatus according to the present invention.
FIG. 2 is a schematic view of the three-dimensional structure of the housing of the apparatus for perfusion preservation and transport of kidney machines of the present invention.
FIG. 3 is a schematic diagram of the three-dimensional structure of a renal jar of the apparatus for perfusion preservation and transport of a kidney.
FIG. 4 is a schematic diagram of the internal structure of the renal jar of the apparatus for perfusion preservation and transport of the kidney of the present invention.
FIG. 5 is a schematic end view of a connector tube of a kidney-use machine perfusion preservation and transport apparatus of the present invention.
FIG. 6 is a schematic diagram of the working principle of the pump body of the kidney perfusion storing and transferring instrument.
FIG. 7 is a schematic carrying view of a machine perfusion preservation and transport apparatus for kidney according to the present invention.
Detailed Description
The following detailed description of the present invention will be made with reference to the accompanying drawings.
The reference numerals and components referred to in the drawings are as follows:
1. case 11. handle
12. Cover 121, handle
2. Kidney jar 21, sealing cover
22. Ice bag 23. sealing strip
3. Pump body 31, liquid inlet
311. Filter 32, liquid outlet
33. Fan blade 34. sensor
35. Blue tooth control system 36, central processing unit
37. Power source 38. power device
4. Connecting pipe 41 air bag
411. Inflation tube 42, telescopic ring
5. Pump body retaining clip 51, opening
6. Kidney frame 7 transplanted kidney
Example 1
Referring to fig. 1, fig. 1 is a schematic plan view of a perfusion preservation and transport apparatus for kidney according to the present invention. A machine perfusion preservation and transfer instrument for kidneys comprises a shell 1, a kidney cylinder 2, a pump body 3, a connecting pipe 4, a pump body fixing frame 5 and a kidney frame 6; the shell 1 is of a concave structure, the inner wall of the shell is of a hollow structure, the two sides of the shell 1 are provided with handles 11, the top of the shell is provided with a cover body 12, and the middle part of the surface of the cover body 12 is provided with a handle 121; the kidney jar 2 is also in a concave structure, the top of the kidney jar is provided with a sealing cover 21, and the surface of the sealing cover 21 is also provided with a handle 121; a preserving fluid (not shown in the figure) can be placed in the kidney jar 2; the kidney jar 2 is arranged inside the shell 1, and ice bags 22 can be filled between the kidney jar 2 and the two sides and the bottom of the shell 1; the pump body 3 comprises a liquid inlet 31, a liquid outlet 32, fan blades 33, a sensor 34, a Bluetooth control system 35, a central controller 36, a power supply 37 and a power device 38; the liquid inlet 31 is arranged at the middle position of the bottom of the pump body 3, and the front end of the liquid inlet 31 is provided with a filtering device 311; the liquid outlet 32 is arranged in the right middle of the pump body; the fan blades 33 are arranged in the pump body 3; the liquid outlet 32 is fixedly connected with the connecting pipe 4; the sensor 34 is arranged at the joint of the liquid outlet 32 of the pump body 3 and the connecting pipe 4; the Bluetooth control system 35 is arranged in the central controller 36; the central controller 36, the power supply 37 and the power device 38 are respectively arranged at independent intervals above the interior of the pump body 3; all the parts in the pump body 3 are mutually connected in a wired or wireless way; the central controller 36 can be connected with an external device through a Bluetooth control system; the pump body fixing frame 5 and the kidney frame 6 are arranged at the bottom of the kidney cylinder 2; the surface of the pump body fixing frame 5 is used for placing and fixing the pump body 3; an opening 51 is formed in the middle of the surface of the pump body fixing frame 5 and used for allowing the liquid inlet 31 of the pump body 3 to pass through; the kidney frame 6 is used for fixedly placing a transplanted kidney; the pump body 3 is fixedly connected with an artery blood vessel on a transplanted kidney 7 by a connecting pipe 4.
It should be noted that: the shell 1 is made of a non-toxic, low-temperature-resistant and high-temperature-resistant sterile plastic material; the inner wall of the shell 1 adopts a hollow structure design, so that the effects of heat insulation and heat preservation are achieved; the design that the ice bag 22 is filled between the kidney jar 2 and the shell 1 can keep the temperature of the preservation solution 22 at 0-4 ℃, thereby keeping the normal physiological characteristics of transplanted kidneys; the kidney cylinder 2 is made of metal materials; the design of the concave structure in the kidney cylinder 2 can ensure that the kidney cylinder 2 is tightly attached to the inner space of the shell 1, thereby preventing the kidney cylinder 2 from overturning while keeping the temperature range of the storage liquid 22 in the kidney cylinder 2; the cover body 12 arranged at the top of the shell 1 is covered at the top of the shell 1 by adopting a jacket type structure, and the handle 121 arranged at the top of the shell 1 facilitates the opening of the cover body 12; the sealing cover 21 arranged at the top of the kidney cylinder 2 is covered around the top of the kidney cylinder 2 by adopting an embedded structure, and structures such as a sealing strip 23 and the like can be arranged between the periphery of the sealing cover 22 and the periphery of the top of the kidney cylinder 2, so that the sterile environment in the kidney cylinder 2 is ensured; the handle arranged on the surface of the sealing cover 21 also plays a role of facilitating the opening of the sealing cover 22; two handles 11 are arranged on two sides of the shell 1, and a movable structure is arranged between the handle 12 and the shell 1, so that the instrument body can be conveniently and directly lifted and taken by a single person through the design of the handle 12, and the instrument is convenient to carry; the pump body 3 is connected with an artery blood vessel on a transplanted kidney 7 through a connecting pipe 4, so that the circulating perfusion preservation effect inside the kidney can be realized; the connection mode between the connecting pipe 4 and the transplanted renal artery blood vessel is an air bag compression type structure, namely, an air bag 41 is arranged around the tail end of the early connecting pipe 4, an inflation pipe 411 with a one-way valve structure is arranged on the air bag 41, when the connection and the fixation are performed, after the tail end of the connecting pipe 4 is arranged in the arterial blood vessel, the air bag 41 is inflated to swell and seal the blood vessel wall, and meanwhile, a telescopic ring 42 is matched with the periphery of the blood vessel to enable the internal and external acting forces of the blood vessel wall to be balanced, so that the connecting pipe 4 and the blood vessel can be fixedly and hermetically connected; the air bag 41 and the telescopic ring 42 are replaceable consumables and are made of plastics or latex materials; the fan blades 33, the sensor 34, the power supply 37 and the power device 38 in the pump body 3 are all connected with the central controller 36 in a wired or wireless manner, and the hollow controller 36 controls the working state of the pump body 3 and the fan blades 33; the fan blades 33 are preferably in a pulse type rotating structure when working, so that the function of simulating blood flow pumping into a transplanted kidney for perfusion, cleaning and preservation can be realized; the power supply 37 is a wireless rechargeable battery, so that the charging is convenient; the central controller 36, the power supply 37 and the power device 38 are arranged above the interior of the pump body 3 at independent intervals, so that the normal working state of the central controller 36 and the power supply 37 can be ensured, and the problem of failure after contacting the preserving fluid 22 is avoided; the hollow controller 36 in the pump body 3 can be connected with external equipment through a wireless Bluetooth system 35, and the external equipment is a mobile phone end or a computer end app and other backstage; the instructions of the central processing unit 36 can be controlled through external equipment, so that the working and stopping of the pump body 3 can be freely controlled, the rotating speed of the fan blades 33 can be controlled, and the use is convenient; when the fan blades 33 in the pump body 3 operate, the preservation solution 22 in the kidney jar 2 enters the pump body 3 through the liquid inlet 31 of the pump body 3, then flows into the connecting pipe 4 from the liquid outlet 32, finally enters the transplanted kidney through the arterial blood vessel and then flows out of the venous blood vessel to the kidney jar 2, thereby realizing the perfusion effect on the circulating machine of the transplanted kidney; the design that the liquid inlet 31 is arranged below the pump body 3 can always keep the liquid inlet 31 arranged in the preservation liquid 22, thereby avoiding the condition of pumping gas, in addition, the filtering device 311 arranged at the front end of the liquid inlet 31 can be a filter screen, and through the design of the filtering device 311, objects such as adipose tissues and the like discharged from a transplanted kidney can be prevented from entering the transplanted kidney from the liquid inlet 31, thereby ensuring the perfusion effect; the sensor 34 arranged at the joint of the liquid outlet 32 and the connecting pipe 4 can transmit data such as temperature, resistance, flow rate and the like of the preservation liquid 22 flowing to the transplanted kidney to the central controller 36, and the external equipment can monitor the machine perfusion condition in real time by receiving the data from the central controller 36, so that the safety of the perfusion process is ensured; the filling time of the machine and the normal range of each data can be set through external equipment, namely mobile phone end or computer end app software, the pump body 3 automatically stops filling when the set time is reached, and an alarm can be automatically given when the monitored data is not in the normal range, so that the filling safety of the machine is ensured; the external equipment is used for facilitating data export and sharing; the pump body fixing frame 5 and the kidney frame 6 which are arranged at the bottom of the kidney cylinder 2 are used for stabilizing the pump body 3 and transplanting the kidney, so that the pump body 3 or the transplanted kidney is prevented from overturning due to vibration of the pump body 3 or flowing of the preservation liquid 22 and the like in the process of perfusion; compared with the existing Life port perfusion instrument, the kidney machine perfusion storage and transfer instrument has the advantages that the volume is reduced to be of an inward concave structure, all data in the perfusion process are transmitted to external equipment, the design of a display screen and other electronic elements is reduced, the transportation and carrying are convenient, and the manufacturing cost of the instrument is reduced.
The invention relates to a machine perfusion preservation and transportation instrument for kidneys, which utilizes the design of filling ice bags between a kidney jar and a shell to keep the temperature of preservation solution at 0-4 ℃, thereby keeping the normal physiological characteristics of transplanted kidneys; the design of the concave structure in the kidney cylinder can ensure that the kidney cylinder is tightly attached to the inner space of the shell, thereby preventing the kidney cylinder from overturning while keeping the temperature range of the stored liquid in the kidney cylinder; the handles arranged on the two sides of the shell are of movable structures with the shell, and the instrument body is convenient for a single person to directly lift and take through the design of the handles, so that the instrument body is convenient to carry; the pump body is connected with the artery blood vessel on the transplanted kidney through a connecting pipe, so that the circulating perfusion preservation effect inside the kidney can be realized; the connecting pipe and the transplanted renal artery blood vessel are in a mode of abutting against each other by internal and external acting forces, so that the effect of sealing and fixing can be ensured; when the fan blade works, the fan blade is of a pulse type rotating structure, so that the blood flow can be simulated to be pumped into the transplanted kidney for perfusion, cleaning and preservation; the central controller and the power supply are arranged above the interior of the pump body at independent intervals, so that the normal working state of the central controller and the power supply can be ensured, and the problem of failure after contacting with the preserving fluid is avoided; the instruction of the central processing unit can be controlled through external equipment, so that the working and stopping of the pump body can be freely controlled, the rotating speed of the fan blades can be controlled, and the use is convenient; when the fan blades in the pump body operate, the preservation solution in the kidney jar enters the pump body through the liquid inlet of the pump body, then flows into the connecting pipe from the liquid outlet, finally enters the transplanted kidney through the arterial blood vessel, and then flows out of the vein blood vessel into the kidney jar, thereby realizing the perfusion effect on the circulating machine of the transplanted kidney; the design that the liquid inlet is arranged below the pump body can always keep the liquid inlet in the preservation liquid, so that the condition of pumping gas is avoided, in addition, the filtering device arranged at the front end of the liquid inlet can avoid objects such as adipose tissues and the like discharged from the transplanted kidney from entering the transplanted kidney through the liquid inlet, so that the perfusion effect is ensured; the sensor arranged at the joint of the liquid outlet and the connecting pipe can transmit data such as temperature, resistance, flow rate and the like of the preservation liquid flowing into the transplanted kidney to the central controller, and the external equipment can monitor the machine perfusion condition in real time by receiving the data from the central controller, so that the safety of the perfusion process is ensured; the filling time of the machine and the normal range of each data can be set through external equipment, the pump body automatically stops filling when the set time is reached, and the alarm can be automatically given when the monitored data is not in the normal range, so that the filling safety of the machine is ensured; the pump body fixing frame and the kidney frame which are arranged at the bottom of the kidney cylinder are used for stabilizing the pump body and transplanting the kidney, so that the pump body or the transplanted kidney is prevented from overturning due to vibration of the pump body or flowing of preservation liquid and the like in the process of perfusion; compared with the existing Life port perfusion instrument, the volume of the kidney perfusion storage and transfer instrument is reduced to be of an inward concave structure, and all data in the perfusion process are transmitted to external equipment, so that the design of a display screen and other electronic elements is reduced, the transportation and carrying are convenient, and the manufacturing cost of the instrument is reduced.
The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications and additions can be made without departing from the method of the present invention, and these modifications and additions should also be regarded as the protection scope of the present invention.
Claims (10)
1. A machine perfusion preservation and transfer instrument for kidneys is characterized by comprising a shell, a kidney cylinder, a pump body, a connecting pipe, a pump body fixing frame and a kidney frame; the shell is of a concave structure, the inner wall of the shell is of a hollow structure, handles are arranged on two sides of the shell, and a cover body is arranged at the top of the shell; the kidney jar is also of a concave structure, and the top of the kidney jar is provided with a sealing cover; the kidney jar can be internally provided with preserving fluid; the kidney jar is arranged in the shell, and ice bags can be filled between the kidney jar and the two sides and the bottom of the shell; the pump body comprises a liquid inlet, a liquid outlet, fan blades, a sensor, a Bluetooth control system, a central controller, a power supply and a power device; the liquid inlet is arranged at the center of the bottom of the pump body, and the front end of the liquid inlet is provided with a filtering device; the liquid outlet is arranged in the right middle of the pump body; the fan blades are arranged in the pump body; the liquid outlet is fixedly connected with the connecting pipe; the periphery of the tail end of the connecting pipe can be provided with an air bag and a telescopic ring; the sensor is arranged at the joint of the pump body liquid outlet and the connecting pipe; the Bluetooth control system is arranged in the central controller; the central controller, the power supply and the power device are respectively arranged above the interior of the pump body; the central controller can be connected with external equipment through a Bluetooth control system; the pump body fixing frame and the kidney are arranged at the bottom of the kidney cylinder; an opening is formed in the middle of the surface of the pump body fixing frame; the pump body is fixedly connected with the artery blood vessel on the transplanted kidney by using a connecting pipe.
2. The apparatus for renal perfusion preservation and transfer of claim 1, wherein the fan is a pulsed rotating structure.
3. The apparatus for renal machine perfusion storage and transfer of claim 1, wherein the filter device is a filter screen.
4. A renal machine perfusion storage and transfer device as in claim 1, wherein the cover and the sealing cap are provided with handles on their surfaces.
5. The apparatus as claimed in claim 1, wherein the external device is a mobile phone or computer app software.
6. A kidney-supplying machine perfusion preservation and transfer apparatus as claimed in claim 1, wherein the fan, sensor, central controller and power source are connected by wireless transmission, and the power source can be charged by wire or wirelessly.
7. A kidney machine perfusion preservation and transfer instrument as claimed in claim 1, wherein a sealing strip is provided between the periphery of the sealing cover and the top of the kidney cylinder.
8. The apparatus for mechanical perfusion preservation and transport of a kidney according to claim 1, wherein the housing is made of a non-toxic, low temperature resistant, high temperature resistant sterile plastic material.
9. The apparatus for renal perfusion preservation and transfer of claim 1, wherein the renal cylinder is made of a metallic material.
10. The apparatus for renal perfusion preservation and transfer of claim 1, wherein the balloon and the extension ring are made of plastic or latex.
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CN201911025470.2A CN110663680A (en) | 2019-10-25 | 2019-10-25 | Machine of confession kidney fills to preserve and transports instrument |
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CN201911025470.2A CN110663680A (en) | 2019-10-25 | 2019-10-25 | Machine of confession kidney fills to preserve and transports instrument |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113892483A (en) * | 2021-09-07 | 2022-01-07 | 奇点医疗科技(广州)有限公司 | Anti-layering filling structure and filling device |
CN115123684A (en) * | 2021-03-24 | 2022-09-30 | 四川省人民医院 | A cooling save set for liver and kidney are transplanted |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002089571A1 (en) * | 2001-05-04 | 2002-11-14 | Breonics, Inc. | Organ chamber for exsanguinous metabolic support system |
US20050026132A1 (en) * | 2000-11-03 | 2005-02-03 | University Of Rochester | Warm intermittent perfusion |
CN1985170A (en) * | 2004-02-02 | 2007-06-20 | 器官恢复系统公司 | Apparatus and method for determining effects of a substance on an organ |
CN101677526A (en) * | 2007-03-01 | 2010-03-24 | 生命线科学有限公司 | Perfusion is regulated |
US20150342177A1 (en) * | 2014-06-02 | 2015-12-03 | Transmedics, Inc | Ex vivo organ care system |
CN210809007U (en) * | 2019-10-25 | 2020-06-23 | 上海长海医院 | Machine perfusion preservation and transport instrument for kidney |
-
2019
- 2019-10-25 CN CN201911025470.2A patent/CN110663680A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050026132A1 (en) * | 2000-11-03 | 2005-02-03 | University Of Rochester | Warm intermittent perfusion |
WO2002089571A1 (en) * | 2001-05-04 | 2002-11-14 | Breonics, Inc. | Organ chamber for exsanguinous metabolic support system |
CN1985170A (en) * | 2004-02-02 | 2007-06-20 | 器官恢复系统公司 | Apparatus and method for determining effects of a substance on an organ |
CN101677526A (en) * | 2007-03-01 | 2010-03-24 | 生命线科学有限公司 | Perfusion is regulated |
US20150342177A1 (en) * | 2014-06-02 | 2015-12-03 | Transmedics, Inc | Ex vivo organ care system |
CN210809007U (en) * | 2019-10-25 | 2020-06-23 | 上海长海医院 | Machine perfusion preservation and transport instrument for kidney |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115123684A (en) * | 2021-03-24 | 2022-09-30 | 四川省人民医院 | A cooling save set for liver and kidney are transplanted |
CN113892483A (en) * | 2021-09-07 | 2022-01-07 | 奇点医疗科技(广州)有限公司 | Anti-layering filling structure and filling device |
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