CN113892483A - Anti-layering filling structure and filling device - Google Patents
Anti-layering filling structure and filling device Download PDFInfo
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- CN113892483A CN113892483A CN202111042567.1A CN202111042567A CN113892483A CN 113892483 A CN113892483 A CN 113892483A CN 202111042567 A CN202111042567 A CN 202111042567A CN 113892483 A CN113892483 A CN 113892483A
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
- A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
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Abstract
The invention discloses a layering-prevention perfusion structure and a perfusion device, wherein the layering-prevention perfusion structure comprises a shell, a mounting bracket, a power assembly and a stirring assembly, a sealed cavity is arranged in the shell, a stirring cavity is formed between the mounting bracket and the shell, a liquid passing hole is formed in the edge of the mounting bracket and is communicated with the stirring cavity, a power element is contained in the sealed cavity, a stirring piece is contained in the stirring cavity, and the stirring piece can rotate under the driving of the power element; the irrigation device includes an anti-stratification irrigation structure. According to the invention, the power element drives the stirring piece to rotate continuously to stir the perfusate, the perfusate is uniformly mixed under the stirring action of the stirring piece, the blood layering degree is reduced, more red blood cells participate in oxygenation circulation by reducing the layering of the perfusate, the oxygenation performance of blood is greatly improved, the viscosity of the perfusate is reduced, the blood consumption in the process of perfusing the isolated organ is reduced, and the perfusion effect of the isolated organ is improved.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a layering prevention perfusion structure and a perfusion device.
Background
In the organ transplantation operation, the transplantation of the solid organ all involves the process of organ separation, blood vessel separation and reunion, the long-time ischemia of the organ can cause the injury, consequently need to perfuse the isolated organ in the perfusion container, in order to adjust the temperature of blood, perfusion pressure, in the correlation technique, because the density of each component of perfusate is different, easily form the layering in the perfusion container, for example, the great component of density such as erythrocyte is piled up in the bottom of perfusion container, cause the blood viscosity to increase, the oxyhemoglobin saturation descends, the vitality of isolated organ reduces, has increased the risk of transplantation operation.
Disclosure of Invention
The present invention is directed to solving at least one of the problems of the prior art. Therefore, the invention provides a stratification-preventing perfusion structure which can reduce blood stratification in a perfusion process and improve the oxygenation performance of a perfusate and the perfusion effect of an isolated organ.
The invention also provides a perfusion device with the anti-layering perfusion structure.
An anti-stratification infusion structure according to an embodiment of the first aspect of the present invention, comprising:
a housing having a sealed cavity therein;
the mounting bracket is connected to one side of the shell, a stirring cavity is formed between the mounting bracket and the shell, a plurality of liquid passing holes are formed in the edge of the mounting bracket, and the liquid passing holes are communicated with the stirring cavity;
the power component comprises a power element, and the power element is accommodated in the sealed cavity;
and the stirring assembly comprises a stirring piece, the stirring piece is accommodated in the stirring cavity, and the stirring piece can rotate under the driving of the power element.
The anti-layering perfusion structure provided by the embodiment of the invention at least has the following beneficial effects:
according to the anti-layering perfusion structure disclosed by the embodiment of the invention, the stirring piece is driven to rotate continuously by the power element, so that the stirring piece is used for stirring the perfusate, the perfusate is uniformly mixed under the stirring action of the stirring piece, the blood layering degree is reduced, more red blood cells participate in oxygenation circulation by reducing the layering of the perfusate, the oxygenation performance of blood is greatly improved, the viscosity of the perfusate is reduced, the blood consumption in the perfusion process of the isolated organ is reduced, and the perfusion effect of the isolated organ is improved.
According to some embodiments of the present invention, the casing includes a partition plate and a rotating shaft, the rotating shaft is inserted into the partition plate and rotatably connected to the partition plate, the stirring chamber and the sealing chamber are respectively disposed at two sides of the partition plate, one end of the rotating shaft is connected to the power element, the other end of the rotating shaft is connected to the stirring member, a sealing member is sleeved outside the rotating shaft, an inner side of the sealing member is disposed in contact with the rotating shaft, and an outer side of the sealing member is disposed in contact with the partition plate.
According to some embodiments of the invention, the power assembly includes a first magnet coupled to the power element, and the stirring assembly includes a second magnet coupled to the stirring member, the first magnet and the second magnet being attracted to each other.
According to some embodiments of the present invention, the power member has a first mounting groove in which the first magnet is embedded, and the stirring member has a second mounting groove in which the second magnet is embedded.
According to some embodiments of the invention, the stirring assembly comprises a cover plate, at least part of the cover plate is embedded in the second mounting groove, and the second magnet is clamped between the stirring piece and the cover plate.
According to some embodiments of the present invention, the casing includes a partition plate, the stirring chamber and the sealed chamber are respectively disposed on two sides of the partition plate, two surfaces of the partition plate opposite to each other are respectively provided with a convex pillar in a protruding manner, and the two convex pillars are respectively connected to the power element and the stirring member.
According to some embodiments of the invention, a gap is provided between the stirring member and the partition plate, and a gap is provided between the stirring member and an end surface of the mounting bracket facing away from the housing.
According to some embodiments of the invention, the housing includes a cover, the cover and the partition are fastened to each other and form the sealed cavity, and the power element is rotatably connected to the cover.
According to some embodiments of the invention, the housing includes an input duct and an output duct, the input duct and the output duct both communicating with the sealed cavity, the power element has a plurality of rotating blades, the input duct is used for inputting flowing fluid into the sealed cavity, and the fluid can drive the power element to rotate and flow out from the output duct.
The perfusion apparatus according to an embodiment of the second aspect of the present invention comprises:
the anti-stratification perfusion structure of the embodiment of the first aspect;
a perfusion container, the anti-stratification perfusion structure being disposed within the perfusion container.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
The invention is further described with reference to the following figures and examples, in which:
FIG. 1 is a schematic structural view of one embodiment of a delamination prevention infusion structure of the present invention;
FIG. 2 is a cross-sectional view of the anti-stratification infusion structure of FIG. 1;
FIG. 3 is an exploded view of the anti-stratification infusion structure of FIG. 1;
FIG. 4 is a schematic structural view of another embodiment of the separator of FIG. 1;
FIG. 5 is a schematic structural view of one embodiment of the power element of FIG. 1;
FIG. 6 is a schematic structural view of one embodiment of the stirring member of FIG. 1;
fig. 7 is a schematic structural view of an embodiment of the perfusion device of the present invention.
Reference numerals:
the sealing device comprises a shell 100, a sealing cavity 110, a partition plate 120, a rotating shaft 130, a sealing element 140, a convex column 150, a cover body 160, an annular bulge 161, an input pipeline 170, an output pipeline 180 and a hose 190. Mounting bracket 200, stirring chamber 210, liquid passing hole 220, support 230 and bottom plate 240. The power assembly 300, a power element 310, a first mounting groove 311, a first rotating groove 312, an annular groove 313, a rotating blade 314, a power shaft 315 and a first magnet 320. The stirring assembly 400, the stirring member 410, the second mounting groove 411, the second rotating groove 412, the stirring shaft 413, the stirring blade 414, the second magnet 420, the cover plate 430, and the filling container 500.
Detailed Description
Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to the same or similar elements or elements having the same or similar function throughout. The embodiments described below with reference to the accompanying drawings are illustrative only for the purpose of explaining the present invention, and are not to be construed as limiting the present invention.
In the description of the present invention, it should be understood that the orientation or positional relationship referred to in the description of the orientation, such as the upper, lower, front, rear, left, right, etc., is based on the orientation or positional relationship shown in the drawings, and is only for convenience of description and simplification of description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
In the description of the present invention, the meaning of a plurality is one or more, the meaning of a plurality is two or more, and the above, below, exceeding, etc. are understood as excluding the present numbers, and the above, below, within, etc. are understood as including the present numbers. If the first and second are described for the purpose of distinguishing technical features, they are not to be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated or implicitly indicating the precedence of the technical features indicated.
In the description of the present invention, unless otherwise explicitly limited, terms such as arrangement, installation, connection and the like should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above terms in the present invention in combination with the specific contents of the technical solutions.
In the description of the present invention, reference to the description of the terms "one embodiment," "some embodiments," "an illustrative embodiment," "an example," "a specific example," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The embodiment of the invention provides a delamination prevention perfusion structure which is used for preventing a perfusate from delaminating in an isolated organ perfusion process. Referring to fig. 1 to 3, the anti-stratification infusion structure includes a housing 100, a mounting bracket 200, a power assembly 300, and an agitation assembly 400, the housing 100 being used for mounting the power assembly 300, and the mounting bracket 200 being used for mounting the agitation assembly 400. Specifically, the housing 100 has a sealed cavity 110 therein, the power assembly 300 includes a power element 310, and the power element 310 is accommodated in the sealed cavity 110 to isolate the power element 310 from the external environment; the mounting bracket 200 is positioned outside the sealed cavity 110, the mounting bracket 200 is connected to one side of the shell 100, a stirring cavity 210 is formed between the mounting bracket 200 and the shell 100, a plurality of liquid passing holes 220 are formed in the edge of the mounting bracket 200, and the stirring cavity 210 is communicated with the liquid passing holes 220; the stirring assembly 400 comprises a stirring piece 410, the stirring piece 410 is accommodated in the stirring cavity 210, the stirring piece 410 can be driven by the power element 310 to rotate, when the stirring piece 410 rotates, the perfusion fluid can be stirred, the rotation of the stirring piece 410 drives the perfusion fluid to continuously enter the stirring cavity 210 from the fluid passing hole 220 for stirring, and the perfusion fluid flows out of the stirring cavity 210 from the fluid passing hole 220, so that the layering at the bottom of the perfusion fluid is broken.
Therefore, in the anti-layering perfusion structure in the embodiment of the invention, the power element 310 drives the stirring piece 410 to rotate continuously, so that the stirring piece 410 stirs the perfusion fluid, the perfusion fluid is uniformly mixed under the stirring action of the stirring piece 410, the blood layering degree is reduced, more red blood cells participate in oxygenation circulation by reducing the layering of the perfusion fluid, the oxygenation performance of blood is greatly improved, the viscosity of the perfusion fluid is reduced, the blood consumption in the perfusion process of the isolated organ is reduced, and the perfusion effect of the isolated organ is improved.
It should be noted that, because the perfusion of the isolated organ has high requirements on the cleanliness of the environment and instruments, in the embodiment of the present invention, the shell 100, the mounting bracket 200, and the stirring member 410 may be made of materials with stable chemical properties, such as PC (polycarbonate), silica gel, and rubber, and may be sterilized to prevent the components from contacting the perfusate to cause the contamination of the perfusate and affect the success rate of the transplantation operation; in addition, the power element 310 is sealed in the sealed cavity 110, and the perfusion fluid only flows in the stirring cavity 210, so that the power element 310 is prevented from polluting the perfusion fluid.
The power element 310 may be a rotary driving member, such as a motor, etc., capable of actively driving the stirring member 410 to rotate, and the power element 310 is connected to the stirring member 410 and provides power for the rotation of the stirring member 410; the power element 310 may also be a transmission member for transmitting power to the stirring implement 410, for example, the power element 310 may be a rotatable rotation body, and the power element 310 is connected to an external driving member and transmits the power of the driving member to the stirring implement 410 to rotate the stirring implement 410.
In one embodiment, the power element 310 and the stirring element 410 are connected by the same shaft, so as to transmit power from the power element 310 to the stirring element 410, as shown in fig. 4, the casing 100 includes a partition 120 and a rotating shaft 130, the rotating shaft 130 is disposed in the partition 120 and connected to the rotating shaft 130 of the partition 120, the stirring cavity 210 and the sealed cavity 110 are disposed on two sides of the partition 120, one end of the rotating shaft 130 is received in the sealed cavity 110 and connected to the power element 310, and the other end of the rotating shaft 130 is received in the stirring cavity 210 and connected to the stirring element 410, so that the stirring element 410 can rotate along with the rotation of the power element 310. In order to ensure the sealing performance of the sealed cavity 110, the housing 100 further includes a sealing member 140, the sealing member 140 is sleeved outside the rotating shaft 130, the inner side of the sealing member 140 contacts the rotating shaft 130, and the outer side of the sealing member 140 contacts the partition plate 120, so that the sealing between the rotating shaft 130 and the partition plate 120 is maintained, and the perfusate is prevented from entering the sealed cavity 110 and causing contamination of the perfusate.
Further, the power element 310 and the stirring element 410 are respectively fixed at two ends of the rotating shaft 130, and the power element 310 and the rotating shaft 130, and the stirring element 410 and the rotating shaft 130 can be relatively fixed by means of adhesion and shaft hole tight fit. As shown in fig. 4, two ends of the rotating shaft 130 are respectively inserted into the power element 310 and the stirring element 410, and a gap is formed between the stirring element 410 and the partition plate 120, so as to prevent the stirring element 410 from rubbing the partition plate 120 during the rotation process and affecting the stirring efficiency of the stirring element 410.
In another embodiment, to ensure the complete sealing of the sealed cavity 110, the power element 310 and the stirring member 410 are in a non-contact manner to realize power transmission. As shown in fig. 2, the power assembly 300 includes a first magnet 320, the first magnet 320 is connected to the power element 310, the first magnet 320 is located in the sealed cavity 110, the stirring assembly 400 includes a second magnet 420, the second magnet 420 is connected to the stirring member 410, the second magnet 420 is located in the stirring cavity 210, the first magnet 320 and the second magnet 420 attract each other, and under the magnetic attraction between the first magnet 320 and the second magnet 420, the stirring member 410 can rotate along with the rotation of the power element 310, so that the stirring member 410 can rotate without being connected to the power element 310, the perfusion fluid can be prevented from entering the sealed cavity 110 due to the connection between the stirring member 410 and the power element 310, and the sealing strength of the sealed cavity 110 is improved.
The first magnet 320 and the second magnet 420 may be respectively opposite magnets that attract each other, or respectively a metal and a magnet that can attract each other. The connecting position of the first magnet 320 and the power element 310 corresponds to the connecting position of the second magnet 420 and the stirring element, so that stable magnetic attraction between the first magnet 320 and the second magnet 420 is ensured, and the stability of power transmission between the power element 310 and the stirring element 410 is improved. In addition, through setting up first magnet 320 and second magnet 420, can increase the weight of preventing the layering filling structure, make the bottom that prevents the layering filling structure and can sink into the perfusate, stir the perfusate, avoid preventing that the layering filling structure floats, and the perfusate of unable stirring bottom improves the stirring effect to the perfusate.
The first magnets 320 and the second magnets 420 may be disposed in plural, the plural first magnets 320 are disposed at different positions of the power element 310, the plural second magnets 420 are disposed at different positions of the stirring member 410, and the positions of the first magnets 320 and the second magnets 420 are in one-to-one correspondence. In an embodiment of the present invention, the first magnet 320 and the second magnet 420 are both annular, so that the first magnet 320 and the second magnet 420 can have a magnetic attraction effect in the entire circumferential direction of the rotation of the stirring element 410, and the stirring element 410 is prevented from shifting during the rotation process to affect the stability of the rotation of the stirring element 410.
The first magnet 320 can be connected with the power element 310 by bonding, and the second magnet 420 can be connected with the stirring piece 410 by bonding, so that other connecting parts are not required to be introduced, the fixing mode is simple, and the cleanliness of the perfusion fluid is not influenced. In one embodiment, referring to fig. 5 and 6, the power member 310 has a first mounting groove 311, the first mounting groove 311 is matched with the shape of the first magnet 320, the first magnet 320 is embedded in the first mounting groove 311, the stirring member 410 has a second mounting groove 411, the second mounting groove 411 is matched with the shape of the second magnet 420, and the second magnet 420 is embedded in the second mounting groove 411; the first magnet 320 can be adhered in the first installation groove 311, the second magnet 420 is adhered in the second installation groove 411, the connection between the first magnet 320 and the power element 310 and the connection between the second magnet 420 and the stirring piece 410 are more compact, and the size of the anti-layering perfusion structure is favorably reduced.
Because the power element 310 and the stirring member 410 adopt a non-contact power transmission mode, the first magnet 320 is sealed in the sealed cavity 110, and the first magnet 320 does not contact the perfusion fluid, in the embodiment of the invention, the second magnet 420 is sealed, for example, after the second magnet 420 is embedded into the second mounting groove 411, glue is filled into the second mounting groove 411, and the second magnet 420 is packaged in the second mounting groove 411, so that the second magnet 420 is prevented from polluting the perfusion fluid; in another embodiment, the stirring assembly 400 further includes a cover plate 430, at least a portion of the cover plate 430 is embedded in the second mounting groove 411, the second magnet 420 is clamped between the stirring member 410 and the cover plate 430, the cover plate 430 may be made of PC, silica gel, rubber, or the like after being sterilized, and the cover plate 430 blocks the second magnet 420 from contacting the perfusion solution, so as to prevent the second magnet 420 from contaminating the perfusion solution.
In order to make the rotation of the power element 310 and the stirring element 410 more stable, in the embodiment of the present invention, the two opposite surfaces of the partition plate 120 are respectively provided with the protruding columns 150 in a protruding manner, the two protruding columns 150 are respectively connected with the power element 310 and the stirring element 410 in a rotating manner, the power element 310 and the stirring element 410 can rotate around the protruding columns 150, during the rotation of the stirring element 410, the partition plate 120 is kept fixed, the power element 310 and the stirring element 410 rotate relative to the protruding columns 150, the protruding columns 150 provide stable rotation axes for the rotation of the power element 310 and the stirring element 410, and support the power element 310 and the stirring element 410, so as to improve the rotation stability of the power element 310 and the stirring element 410.
The convex column 150 should be disposed at the center of the partition 120 for the rotation of the power element 310 and the stirring member 410; the first magnet 320 and the second magnet 420 are both around the outer side of the convex column 150, and the power element 310 and the stirring piece 410 can stably rotate around the convex column 150 all the time under the mutual magnetic attraction effect of the first magnet 320 and the second magnet 420.
In one embodiment of the present invention, a gap is formed between the stirring member 410 and the partition 120, so as to prevent the efficiency of power transmission from the power element 310 to the stirring member 410 from being affected by the mutual friction between the stirring member 410 and the partition 120; similarly, a gap is formed between the power element 310 and the partition 120 to prevent the power element 310 and the partition 120 from rubbing against each other and affecting the power transmission of the power element 310 to the stirring member 410.
It should be noted that, in the embodiment of the present invention, as shown in fig. 3 and fig. 6, a first rotating groove 312 is disposed at the center of the power element 310, a second rotating groove 412 is disposed at the center of the stirring member 410, two protruding columns 150 are respectively inserted into the first rotating groove 312 and the second rotating groove 412, so as to connect the power element 310, the stirring member 410 and the protruding columns 150, the power element 310 and the stirring member 410 are respectively disposed at two sides of the partition plate 120, the top of the protruding column 150 located above abuts against the groove wall of the first rotating groove 312, the bottom of the protruding column 150 located below abuts against the groove wall of the second rotating shaft 130, and under the mutual magnetic attraction effect of the first magnet 320 and the second magnet 420, the power element 310 and the stirring member 410 have a tendency of being close to each other, so that the protruding column 150 continuously abuts against the stirring member 410 and the power element 310, and because the protruding column 150 has a certain length, between the power element 310 and the partition plate 120, and a certain distance can be kept between the stirring element and the partition plate 120 all the time, so that the power element 310 can continuously and stably transmit power to the stirring piece 410; and after the convex column 150 is inserted into the first rotating shaft 130 and the second rotating groove 412, the connection between the partition plate 120 and the power element 310 and the stirring piece 410 can be realized without arranging other matching structures, and the connection convenience is high.
In addition, second magnet 420 is connected in the one side that stirring piece 410 deviates from baffle 120, apron 430 sets up in the one end of keeping away from projection 150, second magnet 420 receives the ascending magnetic attraction of first magnet 320 all the time, and make stirring piece 410 have ascending removal trend, compare in second magnet 420 and connect in the one side that stirring piece 410 is close to baffle 120, apron 430 does not receive the influence of magnetic attraction, prevent that apron 430 is not hard up because the magnetism between first magnet 320 and the second magnet 420 is inhaled, make apron 430 can keep the sealed effect to second magnet 420 all the time.
Further, the end of the convex column 150 is arc-shaped to reduce the contact area between the convex column 150 and the wall of the first rotary groove 312 or the second rotary groove 412, and reduce the friction between the convex column 150 and the power element 310 and the stirring piece 410; alternatively, the top end of the convex pillar 150 may be flattened, and only a part of the arc surface is remained, so as to further reduce the contact area between the convex pillar 150 and the power element 310 and the stirring element 410. The protruding pillar 150 and the partition 120 may be integrally connected, for example, integrally formed by injection molding or stamping, so that the sealed cavity 110 and the stirring cavity 210 are isolated from each other.
In the embodiment of the present invention, the housing 100 further includes a cover 160, the cover 160 and the partition 120 are engaged with each other and form a sealed cavity 110 therebetween, and the power element 310 is rotatably connected to the cover 160. When the anti-lamination perfusion structure is assembled, the first magnet 320 may be first fixed in the first mounting groove 311 of the power element 310, then the power element 310 is connected with the cover 160 and the protruding column 150, and after the partition plate 120 and the cover 160 are encapsulated, the power element 310 is sealed in the sealed cavity 110; then, the second magnet 420 and the cover 160 are installed in the second installation groove 411 and fixed, and after the stirring member 410 is connected with the convex column 150 and the installation bracket 200, the installation bracket 200 is connected and fixed with the partition plate 120, thereby completing the assembly.
The cover body 160 is provided with an annular protrusion 161 protruding towards one side of the sealed cavity 110, one side of the power element 310 facing away from the convex column 150 is provided with an annular groove 313, the annular protrusion 161 is inserted into the annular groove 313, when the power element 310 rotates, the annular protrusion 161 rotates relative to the groove wall of the annular groove 313, and the annular protrusion 161 guides the rotation of the power element 310; moreover, the two sides of the power element 310 are simultaneously supported by the annular protrusion 161 and the convex column 150, and the annular protrusion 161 and the convex column 150 center the axis of the rotating shaft 130 of the power element 310, so that when the power element 310 rotates, the two sides of the power element 310 keep balance, and the rotating smoothness and the power transmission efficiency of the power element 310 can be improved.
It should be noted that, a gap is also formed between the stirring element 410 and the bracket, that is, a gap is formed between the stirring element 410 and the end surface of the bracket facing away from the housing 100, and when the perfusion is performed, the stirring element 410 is lifted up due to the gap, so that the perfusion fluid can flow to the bottom of the stirring element 410, thereby preventing the stirring element 410 from contacting with the ground of the container and rubbing against each other, and ensuring the stirring strength of the stirring element 410 to the perfusion fluid.
The mounting bracket 200 includes a plurality of supporting bodies 230, the supporting bodies 230 are connected to one side of the partition plate 120 opposite to the cover 160 at intervals, the supporting bodies 230 are arranged along the circumferential direction of the partition plate 120, liquid passing holes 220 are formed between adjacent supporting bodies 230, the liquid passing holes 220 are distributed on the periphery of the casing 100, and the perfusate can enter the stirring cavity 210 from different liquid passing holes 220, so as to improve the stirring uniformity of the stirring piece 410 for the perfusate. In one embodiment, the mounting bracket 200 further includes a bottom plate 240, the plurality of supporting bodies 230 are all connected with the bottom plate 240, and the bottom plate 240 is connected to one end of the supporting body 230, which faces away from the partition 120, the bottom plate 240 and the supporting body 230 can be integrally connected, so that the bottom plate 240 and the supporting body 230 can be connected with the partition 120 in an integral structure, the convenience of assembly of the pouring structure is improved, and the bottom plate 240 is arranged to increase the weight of the pouring structure, so that the pouring structure can stir the bottom pouring liquid, in addition, the contact area between the bottom plate 240 and the bottom surface of the container is large, when the stirring member 410 is rotated, the shaking of the pouring structure is reduced, the stability of the pouring structure during operation is improved, and the noise is reduced.
The rotation of the power element 310 can be realized by connecting a wire with an external driving component, for example, the housing 100 further includes a connecting channel, the connecting channel is communicated with the sealed cavity 110, the inner cavity of the connecting channel can allow the wire to pass through, one end of the wire is connected with the power element 310, the other end of the wire is connected with an external driving component, and the rotation of the power element 310 is realized on the premise that the sealed cavity 110 is sealed. It should be noted that the connecting channel should have a certain length to ensure that the end of the connecting channel far from the housing 100 is higher than the liquid level of the perfusion liquid when the perfusion structure is perfused.
In an embodiment of the present invention, the power element 310 is rotated by fluid driving, specifically, the housing 100 includes an input conduit 170 and an output conduit 180, the input conduit 170 and the output conduit 180 are both communicated with the sealed cavity 110, the input conduit 170 is used for conveying fluid into the sealed cavity 110, the output conduit 180 is used for flowing out fluid in the sealed cavity 110, and the power element 310 has a plurality of rotating blades 314. After the fluid flows into the sealed cavity 110 through the input pipe 170, the fluid drives the rotating blade 314 to swing due to the certain flowing speed and pressure of the fluid, so as to realize the rotation of the power element 310, the power element 310 can drive the stirring member 410 to rotate through the magnetic attraction, and the power element 310 continuously drives the stirring member 410 to stir the perfusion fluid along with the continuous entering of the fluid into the sealed cavity 110.
By adopting the fluid driving manner, on one hand, the rotation of the power element 310 is realized, and on the other hand, the rotation of the power element 310 is not influenced by the magnetic field of the magnet, so that the power element 310 can realize the non-contact power transmission with the stirring piece 410 in a magnetic attraction manner.
It is contemplated that the input conduit 170 and/or the output conduit 180 may be provided with a valve body such as a flow valve, a pressure reducing valve, etc. to vary the flow of fluid into the sealed housing 110 to adjust the rotational speed of the stirring element 410. Alternatively, the fluid may be a gas or a liquid, and the flow of the fluid stirs the rotary blade 314 to effect rotation of the power element 310.
The input pipe 170 and the output pipe 180 may be separately disposed on two sides of the housing 100 to avoid turbulence of the fluid in the sealed cavity 110, and a hose 190 may be connected to the end portions of the input pipe 170 and the output pipe 180 to increase the overall length of the pipes, so that the pipes are higher than the level of the perfusion fluid. The power element 310 comprises a power shaft 315 and a plurality of rotating blades 314, the plurality of rotating blades 314 are connected to the periphery of the power shaft 315, and the plurality of rotating blades 314 are simultaneously stirred by the fluid, so that the tangential force applied to the power element 310 is increased, and the rotating speed of the power element 310 can be increased.
As shown in fig. 5, the present invention further provides a perfusion apparatus, the perfusion apparatus includes the above-mentioned anti-stratification perfusion structure, and further includes a perfusion container 500, the anti-stratification perfusion structure is placed in the perfusion container 500, the perfusion container 500 is used for placing an isolated organ and pouring a perfusion solution, the anti-stratification perfusion structure is located at the bottom of the perfusion container 500, a hose connected to the input pipe 170 and the output pipe 180 extends to the top of the perfusion container 500, and when the perfusion solution is perfused, the stirring member 410 stirs the perfusion solution, so as to prevent the perfusion solution from stratification in the perfusion container 500.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge of those skilled in the art without departing from the gist of the present invention. Furthermore, the embodiments of the present invention and the features of the embodiments may be combined with each other without conflict.
Claims (10)
1. An anti-stratification infusion structure, comprising:
a housing having a sealed cavity therein;
the mounting bracket is connected to one side of the shell, a stirring cavity is formed between the mounting bracket and the shell, a plurality of liquid passing holes are formed in the edge of the mounting bracket, and the liquid passing holes are communicated with the stirring cavity;
the power component comprises a power element, and the power element is accommodated in the sealed cavity;
and the stirring assembly comprises a stirring piece, the stirring piece is accommodated in the stirring cavity, and the stirring piece can rotate under the driving of the power element.
2. The delamination-proof filling structure as recited in claim 1, wherein the housing includes a partition and a rotating shaft, the rotating shaft is inserted into the partition and rotatably connected to the partition, the stirring chamber and the sealing chamber are respectively disposed on two sides of the partition, one end of the rotating shaft is connected to the power element, the other end of the rotating shaft is connected to the stirring member, a sealing member is sleeved on an outer portion of the rotating shaft, an inner side of the sealing member is in contact with the rotating shaft, and an outer side of the sealing member is in contact with the partition.
3. The anti-stratification perfusion structure of claim 1, wherein the power assembly comprises a first magnet coupled to the power element, and the agitation assembly comprises a second magnet coupled to the agitation member, the first magnet and the second magnet being attracted to each other.
4. The anti-stratification perfusion structure according to claim 3, wherein the power member has a first mounting groove in which the first magnet is embedded, and the stirring member has a second mounting groove in which the second magnet is embedded.
5. The anti-stratification perfusion structure of claim 4, wherein the stirring assembly comprises a cover plate, at least a portion of the cover plate is embedded in the second mounting groove, and the second magnet is sandwiched between the stirring member and the cover plate.
6. The anti-stratification perfusion structure according to claim 5, wherein the casing includes a partition plate, the stirring chamber and the sealing chamber are respectively disposed at two sides of the partition plate, and two opposite surfaces of the partition plate are respectively provided with protruding columns, and the two protruding columns are respectively connected to the power element and the stirring member.
7. The anti-stratification perfusion structure according to claim 6, wherein a gap is provided between the stirring member and the partition plate, and a gap is provided between the stirring member and an end surface of the mounting bracket facing away from the casing.
8. The delamination-proof pouring structure as recited in claim 6, wherein the housing comprises a cover, the cover and the partition are engaged with each other to form the sealed cavity, and the power element is rotatably connected to the cover.
9. The structure of any one of claims 1 to 8, wherein the housing comprises an input conduit and an output conduit, the input conduit and the output conduit both communicating with the sealed cavity, the power element having a plurality of rotating blades, the input conduit for inputting a fluid flowing into the sealed cavity, the fluid being capable of driving the power element to rotate and to flow out of the output conduit.
10. Perfusion apparatus, characterized in that it comprises:
the anti-stratification perfusion structure of any one of claims 1-9;
a perfusion container, the anti-stratification perfusion structure being disposed within the perfusion container.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111042567.1A CN113892483A (en) | 2021-09-07 | 2021-09-07 | Anti-layering filling structure and filling device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111042567.1A CN113892483A (en) | 2021-09-07 | 2021-09-07 | Anti-layering filling structure and filling device |
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| Publication Number | Publication Date |
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| CN113892483A true CN113892483A (en) | 2022-01-07 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202111042567.1A Pending CN113892483A (en) | 2021-09-07 | 2021-09-07 | Anti-layering filling structure and filling device |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104415405A (en) * | 2013-08-26 | 2015-03-18 | 中国科学院大连化学物理研究所 | Stirred bioreactor convertible in flow direction and for artificial liver |
| CN110432260A (en) * | 2019-03-22 | 2019-11-12 | 天一阁医疗科技(广州)有限公司 | A kind of machine perfusion save set of organism organ |
| CN110663680A (en) * | 2019-10-25 | 2020-01-10 | 上海长海医院 | Machine of confession kidney fills to preserve and transports instrument |
| CN110934131A (en) * | 2019-04-19 | 2020-03-31 | 马大青 | Method for improving preservation quality of organ or composite tissue graft after ischemia-reperfusion |
| CN111165471A (en) * | 2020-03-23 | 2020-05-19 | 郑州大学第一附属医院 | Normal temperature low pressure normal oxygen liver perfusion system |
-
2021
- 2021-09-07 CN CN202111042567.1A patent/CN113892483A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104415405A (en) * | 2013-08-26 | 2015-03-18 | 中国科学院大连化学物理研究所 | Stirred bioreactor convertible in flow direction and for artificial liver |
| CN110432260A (en) * | 2019-03-22 | 2019-11-12 | 天一阁医疗科技(广州)有限公司 | A kind of machine perfusion save set of organism organ |
| CN110934131A (en) * | 2019-04-19 | 2020-03-31 | 马大青 | Method for improving preservation quality of organ or composite tissue graft after ischemia-reperfusion |
| CN110663680A (en) * | 2019-10-25 | 2020-01-10 | 上海长海医院 | Machine of confession kidney fills to preserve and transports instrument |
| CN111165471A (en) * | 2020-03-23 | 2020-05-19 | 郑州大学第一附属医院 | Normal temperature low pressure normal oxygen liver perfusion system |
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