CN110647779A - Information tracking method and system in cell culture process - Google Patents
Information tracking method and system in cell culture process Download PDFInfo
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- CN110647779A CN110647779A CN201810665677.5A CN201810665677A CN110647779A CN 110647779 A CN110647779 A CN 110647779A CN 201810665677 A CN201810665677 A CN 201810665677A CN 110647779 A CN110647779 A CN 110647779A
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- cell culture
- information
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- culture process
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K7/00—Methods or arrangements for sensing record carriers, e.g. for reading patterns
- G06K7/10—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation
- G06K7/14—Methods or arrangements for sensing record carriers, e.g. for reading patterns by electromagnetic radiation, e.g. optical sensing; by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
- G06K7/1404—Methods for optical code recognition
- G06K7/1408—Methods for optical code recognition the method being specifically adapted for the type of code
Abstract
The invention relates to an information tracking method and system in the cell culture process, the method includes obtaining the data in the cell culture process; acquiring operation records of cell culture; and storing the data and the operation records in a database. The invention utilizes the scanned cell information, cell consumable information, reagent and virus information, and the operation parameters of cell culture equipment; and the operation records of the culture personnel are recorded, and the information is stored in the database, so that the tracking of consumables, raw material production and personnel operation records in the cell culture process is realized, each link is strictly regulated, and the cell culture failure rate is reduced.
Description
Technical Field
The invention relates to the technical field of information tracking, in particular to an information tracking method and system in a cell culture process.
Background
At present, cell preparation is mainly performed manually, production process records/data corresponding to cell preparation, records/data of used consumables and raw and auxiliary materials and the like are mainly recorded manually, the manual records have the defects of being untimely, easy to make mistakes, easy to tamper, incomplete, poor in traceability and the like, once cell culture fails or quality problems occur, which link makes mistakes cannot be traced back, errors are likely to be repeatedly made, cell culture failure rate is high, the GMP qualification aspect is challenged, and automatic recording and tracing of the whole cell culture process by using a computer system are one of the modes for making up the defects.
Therefore, it is necessary to design an information tracking method in the cell culture process, so as to track consumables, raw material production and personnel operation records in the cell culture process, strictly standardize each link, reduce the cell culture failure rate, and ensure that the whole process has records and can be traced.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides an information tracking method and system in a cell culture process.
In order to achieve the purpose, the invention adopts the following technical scheme: a method of information tracking in a cell culture process, the method comprising:
acquiring data in the cell culture process;
acquiring operation records of cell culture;
and storing the data and the operation records in a database.
The further technical scheme is as follows: the step of obtaining data during cell culture comprises the following specific steps:
scanning codes to obtain cell information;
scanning the code to obtain cell consumable material information;
scanning the code to obtain reagent and virus information.
The further technical scheme is as follows: after the step of scanning the code to obtain the reagent and the virus information, the method further comprises the following steps:
the operating parameters of the cell culture apparatus were recorded.
The invention also provides an information tracking system in the cell culture process, which comprises a data acquisition unit, an operation record acquisition unit and a storage unit;
the data acquisition unit is used for acquiring data in the cell culture process;
the operation record acquisition unit is used for acquiring operation records of cell culture;
and the storage unit is used for storing the data and the operation records in the database.
The further technical scheme is as follows: the data acquisition unit comprises a first code scanning module, a second code scanning module and a third code scanning module;
the first code scanning module is used for scanning codes to acquire cell information;
the second code scanning module is used for scanning codes to obtain cell consumable material information;
and the third code scanning module is used for scanning codes to obtain reagents and virus information.
The further technical scheme is as follows: the operation record acquisition unit further comprises a parameter recording module;
the parameter recording module is used for recording the operation parameters of the cell culture equipment.
Compared with the prior art, the invention has the beneficial effects that: according to the information tracking method in the cell culture process, the scanned cell information, the cell consumable material information, the reagent and virus information and the operation parameters of cell culture equipment are utilized; and the operation records of the culture personnel are recorded, and the information is stored in the database, so that the tracking of consumables, raw material production and personnel operation records in the cell culture process is realized, each link is strictly specified, the cell culture failure rate is reduced, and the recording and traceability of the whole process are ensured.
The invention is further described below with reference to the accompanying drawings and specific embodiments.
Drawings
FIG. 1 is a flow chart of a method for tracking information during a cell culture process according to an embodiment of the present invention;
FIG. 2 is a flow chart of data acquisition during cell culture according to an embodiment of the present invention;
FIG. 3 is a block diagram of an information tracking system for cell culture process according to an embodiment of the present invention;
fig. 4 is a block diagram of an operation record obtaining unit according to an embodiment of the present invention.
Detailed Description
In order to more fully understand the technical content of the present invention, the technical solution of the present invention will be further described and illustrated with reference to the following specific embodiments, but not limited thereto.
As shown in fig. 1 to 4, the information tracking method in the cell culture process provided in this embodiment can be applied to the cell culture or other substance culture processes, and can track the consumables, raw material production, and personnel operation records in the cell culture process, strictly standardize each link, reduce the cell culture failure rate, and ensure that the whole process has records and can be traced.
As shown in fig. 1, the present embodiment provides an information tracking method in a cell culture process, the method comprising:
s1, acquiring data in the cell culture process;
s2, obtaining operation records of cell culture;
and S3, storing the data and the operation records in the database.
Further, as for the step of S1, the step of acquiring data during the cell culture process includes the following specific steps:
s11, scanning codes to obtain cell information;
s12, scanning the code to obtain cell consumable information;
s13, scanning the code to obtain the reagent and virus information.
For the above steps S11 to S13, the code scanning device (such as a code scanning gun or a code scanning machine) scans the cell information, the cell consumable information, the reagent information and the virus information. Integrate cell information, cell consumptive material information, reagent and virus information on the bar code, sweep the sign indicating number and obtain, convenient operation, the practicality is strong.
Further, in some embodiments, after the step of scanning the code to obtain the reagent and the virus information in step S13, the method further includes:
and S14, recording the operation parameters of the cell culture equipment.
Besides the cell information, cell consumable information, reagent and virus information influence the culture of cells, certain influence is exerted on the operation parameters of the cell culture equipment, such as the parameters of temperature, humidity and the like of the environment control equipment, the rotation speed, angle and the like of the centrifugal machine, information tracking is required, and the values of the parameters are strictly controlled.
In addition, the operation record of the culturist also plays a key role in the success rate of cell culture in the step S2.
If the cell culture fails, finding out reasons from cell information, cell consumable information, reagent and virus information, operation parameters of cell culture equipment and operation records of culture personnel for correction so as to reduce the culture failure rate of the cells.
According to the information tracking method in the cell culture process, the scanned cell information, the cell consumable information, the reagent and virus information and the operation parameters of the cell culture equipment are utilized; and the operation records of the culture personnel are recorded, and the information is stored in the database, so that the tracking of consumables, raw material production and personnel operation records in the cell culture process is realized, each link is strictly specified, the cell culture failure rate is reduced, and the recording and traceability of the whole process are ensured.
As shown in fig. 3, the present embodiment also provides an information tracking system in a cell culture process, which includes a data acquisition unit 1, an operation record acquisition unit 2, and a storage unit 3.
A data acquisition unit 1 for acquiring data during cell culture.
An operation record acquiring unit 2 for acquiring an operation record of cell culture.
And the storage unit 3 is used for storing the data and the operation records in the database. And the data can not be tampered, and the requirement of data integrity is met.
Further, in some embodiments, the data acquisition unit 1 includes a first code scanning module 11, a second code scanning module 12, and a third code scanning module 13. These sweep a yard module and can increase and decrease according to material quantity.
The first code scanning module 11 is used for scanning codes to acquire cell information.
And the second code scanning module 12 is used for scanning codes to acquire cell consumable information.
And the third code scanning module 13 is used for scanning codes to obtain reagents and virus information.
Specifically, a code scanning device (such as a code scanning gun or a code scanning machine) scans cell information, cell consumable information, reagent information and virus information. Integrate cell information, cell consumptive material information, reagent and virus information on the bar code, sweep the sign indicating number and obtain, convenient operation, the practicality is strong.
In addition, in some embodiments, the operation record obtaining unit 2 further includes a parameter recording module 14.
And the parameter recording module 14 is used for recording the operating parameters of the cell culture equipment.
Besides the cell information, cell consumable information, reagent and virus information influence the culture of cells, certain influence is exerted on the operation parameters of the cell culture equipment, such as the parameters of temperature, humidity and the like of the environment control equipment, the rotation speed, angle and the like of the centrifugal machine, information tracking is required, and the values of the parameters are strictly controlled.
In addition, with the above-described operation record acquisition unit 2, the operation record of the culture personnel also plays a key role in the success rate of cell culture.
If the cell culture fails, finding out reasons from cell information, cell consumable information, reagent and virus information, operation parameters of cell culture equipment and operation records of culture personnel for correction so as to reduce the culture failure rate of the cells.
According to the information tracking system in the cell culture process, the scanned cell information, the cell consumable information, the reagent and virus information and the operation parameters of the cell culture equipment are utilized; and the operation records of the culture personnel are recorded, and the information is stored in the database, so that the tracking of consumables, raw material production and personnel operation records in the cell culture process is realized, each link is strictly specified, the cell culture failure rate is reduced, and the recording and traceability of the whole process are ensured.
The technical contents of the present invention are further illustrated by the examples only for the convenience of the reader, but the embodiments of the present invention are not limited thereto, and any technical extension or re-creation based on the present invention is protected by the present invention. The protection scope of the invention is subject to the claims.
Claims (6)
1. A method for tracking information during a cell culture process, the method comprising:
acquiring data in the cell culture process;
acquiring operation records of cell culture;
and storing the data and the operation records in a database.
2. The method for tracking information in the cell culture process according to claim 1, wherein the step of acquiring data in the cell culture process comprises the following specific steps:
scanning codes to obtain cell information;
scanning the code to obtain cell consumable material information;
scanning the code to obtain reagent and virus information.
3. The method of claim 2, wherein the step of scanning the code to obtain the reagent and the virus information further comprises:
the operating parameters of the cell culture apparatus were recorded.
4. An information tracking system in the process of cell culture is characterized by comprising a data acquisition unit, an operation record acquisition unit and a storage unit;
the data acquisition unit is used for acquiring data in the cell culture process;
the operation record acquisition unit is used for acquiring operation records of cell culture;
and the storage unit is used for storing the data and the operation records in the database.
5. The system for tracking information in the cell culture process according to claim 4, wherein the data acquisition unit comprises a first code scanning module, a second code scanning module and a third code scanning module;
the first code scanning module is used for scanning codes to acquire cell information;
the second code scanning module is used for scanning codes to obtain cell consumable material information;
and the third code scanning module is used for scanning codes to obtain reagents and virus information.
6. The system for tracking information in the cell culture process according to claim 5, wherein the operation record obtaining unit further comprises a parameter recording module;
the parameter recording module is used for recording the operation parameters of the cell culture equipment.
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| CN201810665677.5A CN110647779A (en) | 2018-06-26 | 2018-06-26 | Information tracking method and system in cell culture process |
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| CN201810665677.5A CN110647779A (en) | 2018-06-26 | 2018-06-26 | Information tracking method and system in cell culture process |
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Cited By (1)
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| CN111476517A (en) * | 2020-03-13 | 2020-07-31 | 青岛海尔生物医疗股份有限公司 | Cell culture management system |
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