A kind of Cell Culture Lab total management system and method
Technical field
The present invention relates to Design of Laboratory Management System technical field, and in particular to a kind of Cell Culture Lab integrated management system
System and method.
Background technology
The cell culture experimental technique means indispensable as modern medicine or even whole life science, are all kinds of
The important component of experimental technique platform.Cell culture is more embodied in culture skill in addition to needing consummate operating technology
The process of art is complicated, and sterile requirement is strict.The factor of influence cell culture success or failure is a lot, and any one link goes wrong,
It is unqualified Cell-Culture products to be directly resulted in.The management of Cell Culture Lab at this stage is mainly by hand-kept and reality
Room on-the-spot guidance supervision is tested, who enters whose management of laboratory, as a result causes to suffer setbacks repeatedly in cell cultivation process.For carrying out
It is independent that the mechanism of cell culture business, its business department, production division, logistics department etc. commence business in the process of running
, cause to carry out in cell culture business procedure, because linking up delay or not smooth, cell culture failure easily occur, cause the time
And cost allowance, it is often more important that most probably for being badly in need of impacting using the unit or personnel of cell.Therefore, for whole
Individual cell culture business and Cell Culture Lab, it is badly in need of effective total management system, owns in integrator cell incubation
Link, carry out unified management control, improve the control dynamics in incubation, ensure cell culture operation flow and cell training
Foster laboratory being capable of normal operation., can be right during exquisite detail experiment by Cell Culture Lab total management system
In the operational circumstances of material, the service condition of equipment, in real time monitoring producers.
Existing Routine Test Lab workflow management software, relate generally to traditional laboratory room managing flow.Functionally without
Method meets the control of each link of cell culture operation flow, and can not more meet cell cultivation process and quality control process management will
Ask.
In addition, prior art at cross-platform aspect there is also defect, with the popularization and variation of access terminals, across setting
Standby, cross-platform display becomes more and more important, and prior art only realizes the use of PC terminals, can not meet the collaboration of multiple terminals
Management.
The content of the invention
In view of the shortcomings of the prior art, the present invention is intended to provide a kind of Cell Culture Lab total management system and side
Method, by rational Functional Design, system module design, effectively realize to cell culture experiments whole process integrated management, it is real
The real-time electronic monitoring management held before, during and after existing whole flow process, improves operating efficiency.And it is using towards Interface design
System framework, the accesses of operatively compatible various operation terminals, adapts to the use demand of a variety of mobile contexts of Modern Laboratory, realizes
Multiple terminals coordinated management.For cell cultivation process management, real-time monitoring record is carried out, culture data are uploaded, ensured whole in real time
Individual incubation meets production requirement, for cell culture Management of quality control, is used by equipment, consumptive material uses, detection records
The real-time typing of data and record, ensure trackability, it is ensured that production cell quality.
To achieve these goals, the present invention adopts the following technical scheme that:
A kind of Cell Culture Lab total management system, including cell culture experiments comprehensive management module, cell culture
Process management module, cell culture Management of quality control module;
The cell culture experiments comprehensive management module includes client information management module, cell sample freezes management mould
Block, purchasing management module, inventory management module, culture project management module, personal management module, data query and statistics mould
Block;
The cell cultivation process management module includes cell culture task module, cell culture logging modle, cultivated
Journey picture recording module;
The cell culture Management of quality control module, which includes culture record supervisor module, culture video recording supervisor module, instrument, to be made
Tracing module is flowed to record supervisor module, microorganism detection logging modle, cell detection logging modle, reagent consumptive material.
On the basis of above-mentioned technical proposal, the client information management module is used for managing customer information;The cell
Sample freezes management module and freezes sample information record management for client;The purchasing management module is used to purchase reagent consumption
Material;The inventory management module is used for the Inventory Performance of control inspection reagent consumptive material;The culture project management module is used to manage
Manage cell culture project;The personal management module is used to manage cell culture personnel;The data query and statistical module are used
In tracing the buying situation of reagent consumptive material, get situation and service condition.
On the basis of above-mentioned technical proposal, the cell culture task module is used to record cell culture task;It is described
Cell culture logging modle is used for growth conditions, cell quantity, cell photo, the growth course video record for recording cell, training
The data such as actual reagent consumption, instrument usage record during supporting;The incubation picture recording module is used to record cell training
Operational circumstances during supporting.
On the basis of above-mentioned technical proposal, culture record supervisor's module is used for the culture record for verifying culture person;
Culture video recording supervisor's module is used for the video recording of cell growth process video and carries out long-range Quality Control;The instrument usage record is superintended and directed
Module is examined to be used to carry out long-range Quality Control to instrument usage record data;The microorganism detection logging modle is used for cell culture
In microorganism detection result data recorded;The cell detection logging modle is used for the growth conditions to cell, cell
The data such as quantity, cell photo carry out long-range Quality Control;The reagent consumptive material flows to tracing module and is used for the reality in incubation
Border reagent consumptive material flows to data and carries out long-range Quality Control.
A kind of Cell Culture Lab flow Management of quality control method, using above-mentioned Cell Culture Lab integrated management system
System, comprises the following steps:
(1) when producing culture order, related management personnel pass through customer information typing client information management module
Culture project management module establishes culture project;
(2) after receiving the sample of client in laboratory, sample is frozen, and recorded cell sample and freeze management mould
Block;
(3) external coordination personnel in laboratory audit order and whether sample information matches, checks reagent by inventory management module
Whether consumptive material is complete, if matching and complete, cellulation culture task, and would upload to cell culture task module;If
Reagent consumptive material deficiency by purchasing management module, it is necessary to purchase novel agent consumptive material;
(4) cell culture person gets cultivate reagent, proceeds by the culture of cell, together according to cell culture mission requirements
When typing culture project management module and personal management module;
(5) cell culture person remembers cell cultivation process, it is necessary to open multimedia video recording equipment in cell cultivation process
Record incubation picture recording module;
(6) cell culture person is needed after daily cell culture task is completed, and passes through mobile terminal or PC terminal handles
Growth conditions, cell quantity, cell photo, the growth course video record of cell, the actual reagent consumption in incubation, instrument
The data such as device usage record, it imperfectly recorded in culture record, upload to cell culture logging modle;
(7) Quality Control personnel can be verified every daily by mobile terminal or PC terminals by cell culture Management of quality control module
The culture record of individual culture person, carries out long-range Quality Control, Quality Control scope includes:The growth conditions of cell, cell quantity, cell shine
Piece, cell growth process video record, the data such as actual reagent consumption, instrument usage record in incubation;
(8) cell cultivation process key node, it is necessary to carry out necessary detection to cell, testing result needs to upload
To cell detection logging modle;
(9) until the culture of completion cell, culture task is closed;
(10) if Quality Control personnel have found that certain batch reagent has problem, can be integrated by the Cell Culture Lab
Purchasing management module, inventory management module and the data query and statistical module of management system directly trace adopting for the batch products
Purchase situation, situation and service condition, and then the effectively coverage of control problem are got, trace question classification.
On the basis of above-mentioned technical proposal, the sample of client includes blood and histocyte in step (2).
On the basis of above-mentioned technical proposal, the product in step (10) is reagent consumptive material.
The invention has the advantages that:
By the system and method for the present invention, effective linking to each link of cell culture workflow have effectively achieved
And management, the use flow direction to cell cultivation process each time, cell culture result and each batch reagent consumptive material exercise supervision
Control, meets the requirement of cell cultivation process and quality control process management.Multimedia technology and network are innovatively utilized, to cell
Growth course, cell culture operations process carry out multimedia video recording.
Using the architecture design towards interface, and the system architecture of multiple terminals collaboration is realized, adapt to modern multiple terminals ring
User's use habit under border, and then Quality Control scope and ability are expanded, the efficiency and effect of Management of quality control are improved, is realized
Remotely, efficient Management of quality control.
Brief description of the drawings
The present invention has drawings described below:
Fig. 1 Cell Culture Lab total management system structural representations.
Fig. 2 Cell Culture Lab flow Management of quality control schematic diagrames.
Embodiment
The present invention is described in further details below in conjunction with accompanying drawing and specific implementation case.
As shown in figure 1, a kind of Cell Culture Lab total management system, including cell culture experiments integrated management mould
Block, cell cultivation process management module, cell culture Management of quality control module;
The cell culture experiments comprehensive management module includes client information management module, cell sample freezes management mould
Block, purchasing management module, inventory management module, culture project management module, personal management module, data query and statistics mould
Block;
The cell cultivation process management module includes cell culture task module, cell culture logging modle, cultivated
Journey picture recording module;
The cell culture Management of quality control module, which includes culture record supervisor module, culture video recording supervisor module, instrument, to be made
Tracing module is flowed to record supervisor module, microorganism detection logging modle, cell detection logging modle, reagent consumptive material.
On the basis of above-mentioned technical proposal, the client information management module is used for managing customer information;The cell
Sample freezes management module and freezes sample information record management for client;The purchasing management module is used to purchase reagent consumption
Material;The inventory management module is used for the Inventory Performance of control inspection reagent consumptive material;The culture project management module is used to manage
Manage cell culture project;The personal management module is used to manage cell culture personnel;The data query and statistical module are used
In tracing the buying situation of reagent consumptive material, get situation and service condition.
On the basis of above-mentioned technical proposal, the cell culture task module is used to record cell culture task;It is described
Cell culture logging modle is used for growth conditions, cell quantity, cell photo, the growth course video record for recording cell, training
The data such as actual reagent consumption, instrument usage record during supporting;The incubation picture recording module is used to record cell training
Operational circumstances during supporting.
On the basis of above-mentioned technical proposal, culture record supervisor's module is used for the culture record for verifying culture person;
Culture video recording supervisor's module is used for the video recording of cell growth process video and carries out long-range Quality Control;The instrument usage record is superintended and directed
Module is examined to be used to carry out long-range Quality Control to instrument usage record data;The microorganism detection logging modle is used for cell culture
In microorganism detection result data recorded;The cell detection logging modle is used for the growth conditions to cell, cell
The data such as quantity, cell photo carry out long-range Quality Control;The reagent consumptive material flows to tracing module and is used for the reality in incubation
Border reagent consumptive material flows to data and carries out long-range Quality Control.
As shown in Fig. 2 a kind of Cell Culture Lab flow Management of quality control method, comprehensive using above-mentioned Cell Culture Lab
Management system is closed, is comprised the following steps:
(1) when producing culture order, related management personnel pass through customer information typing client information management module
Culture project management module establishes culture project;
(2) after receiving the sample of client in laboratory, sample is frozen, and recorded cell sample and freeze management mould
Block;
(3) external coordination personnel in laboratory audit order and whether sample information matches, checks reagent by inventory management module
Whether consumptive material is complete, if matching and complete, cellulation culture task, and would upload to cell culture task module;If
Reagent consumptive material deficiency by purchasing management module, it is necessary to purchase novel agent consumptive material;
(4) cell culture person gets cultivate reagent, proceeds by the culture of cell, together according to cell culture mission requirements
When typing culture project management module and personal management module;
(5) cell culture person remembers cell cultivation process, it is necessary to open multimedia video recording equipment in cell cultivation process
Record incubation picture recording module;
(6) cell culture person is needed after daily cell culture task is completed, and passes through mobile terminal or PC terminal handles
Growth conditions, cell quantity, cell photo, the growth course video record of cell, the actual reagent consumption in incubation, instrument
The data such as device usage record, it imperfectly recorded in culture record, upload to cell culture logging modle;
(7) Quality Control personnel can be verified every daily by mobile terminal or PC terminals by cell culture Management of quality control module
The culture record of individual culture person, carries out long-range Quality Control, Quality Control scope includes:The growth conditions of cell, cell quantity, cell shine
Piece, cell growth process video record, the data such as actual reagent consumption, instrument usage record in incubation;
(8) cell cultivation process key node, it is necessary to carry out necessary detection to cell, testing result needs to upload
To cell detection logging modle;
(9) until the culture of completion cell, culture task is closed;
(10) if Quality Control personnel have found that certain batch reagent has problem, can be integrated by the Cell Culture Lab
Purchasing management module, inventory management module and the data query and statistical module of management system directly trace adopting for the batch products
Purchase situation, situation and service condition, and then the effectively coverage of control problem are got, trace question classification.
On the basis of above-mentioned technical proposal, the sample of client includes blood and histocyte in step (2).
On the basis of above-mentioned technical proposal, the product in step (10) is reagent consumptive material.
For those skilled in the art, technical scheme that can be more than and design, make various corresponding
Change and deform, and all these change and deformation should be construed as being included within the protection domain of the claims in the present invention.
The content not being described in detail in this specification belongs to prior art known to professional and technical personnel in the field.