CN110646233B - Cell diagnosis is with quantitative sampling device - Google Patents
Cell diagnosis is with quantitative sampling device Download PDFInfo
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- CN110646233B CN110646233B CN201911151867.6A CN201911151867A CN110646233B CN 110646233 B CN110646233 B CN 110646233B CN 201911151867 A CN201911151867 A CN 201911151867A CN 110646233 B CN110646233 B CN 110646233B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/26—Inoculator or sampler
Abstract
The invention relates to the technical field of medical instruments and discloses a quantitative sampling device for cell diagnosis, which comprises a supporting plate, wherein the bottom of the supporting plate is fixedly connected with a first threaded ring, the inner wall of the first threaded ring is in threaded connection with a sampling needle, the upper surface of the supporting plate is provided with a pushing mechanism, and the inner wall of the supporting plate and the inner wall of the sampling needle are both in sliding connection with the surface of the pushing mechanism. According to the invention, by arranging the pushing mechanism, the sampling sleeve, the air exhaust mechanism, the air groove, the sealing mechanism and the air hole, when cells enter the sampling sleeve, the gravity of the sampling sleeve is increased, when the gravity of the sampling sleeve is greater than that of the first spring, the sampling sleeve moves downwards to open the air groove, at the moment, the air exhaust plate cannot continuously drive the sliding plate to move upwards, the sliding plate returns to the initial position under the action of the second spring, the fourth straight pipe and the bent pipe are sealed, and then the cells are stopped being extracted, so that quantitative sampling is realized.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a quantitative sampling device for cell diagnosis.
Background
At present, the cell diagnosis is mainly to use a syringe and a needle head to cooperate to suck cells of a pathological change part, when a needle tip passes through skin and subcutaneous tissues under normal pressure and reaches the pathological change area, a piston core rod is pulled to generate negative pressure in the syringe, the pathological change cells are sucked and then retreat out of the subcutaneous tissues and the skin, and the pathological change cells are placed on a smear for observation. However, most of the existing sampling devices do not have the function of quantitative sampling, for example, chinese patent publication No. CN201720431678.4 discloses a needle-aspiration cell sampler, which pumps cells into a needle cylinder through a piston, but during sampling, the sampling amount of the cells cannot be determined, if the sampling amount is too small, the diagnosis requirement cannot be met, the sampling needs to be performed again, and if the sampling amount is too large, the redundant cells are troublesome to handle, and thus the user is not convenient to use the sampler to perform sampling.
Disclosure of Invention
The invention aims to solve the defects in the prior art, such as: most of the existing sampling devices do not have the function of quantitative sampling, and during sampling, if the sampling amount is too small, the diagnosis requirement cannot be met, then the sampling needs to be carried out again, and if the sampling amount is too large, the redundant cells are troublesome to process, so that the quantitative sampling device for cell diagnosis is provided.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a cell diagnosis is with quantitative sampling device, includes the backup pad, the first screw thread ring of bottom fixedly connected with of backup pad, the inner wall threaded connection of first screw thread ring has the sample syringe needle, the upper surface of backup pad is provided with pushing mechanism, the inner wall of backup pad and the inner wall of sample syringe needle all with pushing mechanism's sliding surface connection, pushing mechanism inner wall sliding connection has the third straight tube, the outer fixed surface of third straight tube is connected with sealed lid, the outer surface threaded connection of sealed lid has the sample sleeve.
The equal sliding connection in sample sleeve's the left and right sides has the connecting block, the bottom of connecting block is connected with the last fixed surface of backup pad, the last fixed surface of connecting block is connected with second threaded ring, the inner wall threaded connection of second threaded ring has the sleeve of bleeding, the telescopic surface of bleeding and sample sleeve's inner wall sliding connection.
The telescopic inner wall fixedly connected with air exhaust mechanism bleeds, the gas pocket has been seted up to the telescopic bottom of bleeding, the telescopic inner wall fixedly connected with spacing ring of sample, the upper surface of spacing ring and the telescopic bottom contact of bleeding, the telescopic inner wall fixedly connected with sealing mechanism of sample, sealing mechanism is located between spacing ring and the sealed lid, the telescopic inner wall sliding connection of sample has the third baffle, the bottom of third baffle and the upper surface contact of sealed lid, the gas pocket has all been seted up to the telescopic front and back both sides of sample, the gas pocket is located sealing mechanism's front and back both sides.
Preferably, pushing mechanism includes first straight tube, the inner wall of backup pad and the inner wall of sample syringe needle all with the surface sliding connection of first straight tube, the fixed surface of first straight tube is connected with first baffle, the bottom of first baffle and the upper surface contact of backup pad, the last fixed surface of first baffle is connected with first spring, the last fixed surface of first spring is connected with the second baffle, the bottom fixedly connected with second straight tube of second baffle, the inner wall of second straight tube and the surface sliding connection of first straight tube, the inner wall of second straight tube and the inner wall of second baffle all with the surface sliding connection of third straight tube, the upper surface of second baffle and the bottom contact of sealed lid.
Preferably, the air exhaust mechanism comprises an air exhaust plate, the outer surface of the air exhaust plate is in sliding connection with the inner wall of the air exhaust sleeve, the upper surface of the air exhaust plate is fixedly connected with a connecting column, the upper surface of the connecting column is fixedly connected with a handle plate, the bottom of the handle plate is in contact with the upper surface of the air exhaust sleeve, the outer surface of the connecting column is in sliding connection with a support ring, the outer surface of the support ring and the inner wall of the air exhaust sleeve are fixedly connected with fixing columns, and the air exhaust plate is located above the air groove.
Preferably, the sealing mechanism comprises a fourth straight pipe, the left side and the right side of the fourth straight pipe are fixedly communicated with bent pipes, the outer surface of each bent pipe is fixedly communicated with a first fixing plate, the upper surface of each first fixing plate is fixedly connected with the bottom of the fourth straight pipe, the outer surface of each fourth straight pipe is fixedly connected with a second fixing plate, the second fixing plate is positioned below an air hole, the upper surface of each second fixing plate is fixedly connected with a second spring, the upper surface of each second spring is fixedly connected with a sliding plate, the sliding plate is positioned above the air hole, the inner wall of each sliding plate is fixedly connected with the outer surface of the fourth straight pipe, the upper surface of each sliding plate is fixedly connected with a blocking column, the upper surface of each blocking column is fixedly connected with a sealing plate, the bottom of each sealing plate is in contact with the upper surface of the fourth straight pipe, and the bottom of each sealing, the left and right sides of the sealing column are in sliding connection with one side of the bent pipe close to the sealing column.
Preferably, the sealing column is a regular quadrangular prism, and the width of the sealing column is larger than the diameter of the bent pipe.
Preferably, a pull ring is fixedly connected to the upper surface of the sealing plate.
Preferably, the front of the air exhaust sleeve is provided with a groove, the inner wall of the groove is fixedly connected with a graduated scale, and the front of the graduated scale is in sliding connection with the inner wall of the second threaded ring.
Preferably, the bottom of aspirating plate is provided with first dust screen, the surface of first dust screen and the telescopic inner wall fixed connection of bleeding, the top of support ring is provided with the second dust screen, the inner wall of second dust screen and the surface sliding connection of spliced pole, the surface of second dust screen and the telescopic inner wall fixed connection of bleeding.
Preferably, the front side and the rear side of the sampling sleeve are fixedly connected with a third dust prevention net, and the center of the third dust prevention net and the center of the air hole are in the same horizontal plane.
Compared with the prior art, the invention has the beneficial effects that:
(1) the invention increases the gravity of the sampling sleeve by arranging the pushing mechanism, the sampling sleeve, the air exhaust mechanism, the air groove, the sealing mechanism and the air hole, when the gravity of the sampling sleeve is larger than the gravity of the first spring, the sampling sleeve moves downwards to open the air groove, at the moment, the air exhaust plate can not continuously drive the sliding plate to move upwards, so that the sliding plate returns to the initial position under the action of the second spring, the fourth straight pipe and the bent pipe are sealed through the sealing plate and the sealing column, the cell extraction is stopped, the quantitative sampling is realized, the use is convenient, meanwhile, after the fourth straight pipe and the bent pipe are sealed, the air quantity between the third baffle plate and the first fixing plate can not be changed, the third baffle plate is fixed, after the air groove is prevented from being opened, the third baffle plate pushes the cells in the sampling sleeve under the action of the gravity, the cells were refluxed, resulting in a reduced sample size.
(2) According to the invention, the second threaded ring and the limiting ring are arranged, the first spring pushes the sampling sleeve to enable the limiting ring to be in close contact with the air exhaust sleeve, when the cell sampling amount needs to be changed, the air exhaust sleeve is rotated to enable the air exhaust sleeve to move up and down through the second threaded ring, at the moment, the sampling sleeve is enabled to move up and down through the left and right lower parts of the limiting ring, the pushing force of the first spring on the sampling sleeve is adjusted, the gravity needed when the sampling sleeve moves down is changed, the sampling amount of cells in the sampling sleeve is further changed, a user can conveniently extract cells with different weights as required, meanwhile, the position of the second threaded ring is conveniently observed by the user through the arrangement of the graduated scale, and the user can conveniently judge the sampling amount of the cells.
(3) According to the invention, through arranging the first threaded ring and the second threaded ring, after sampling is finished, the sampling needle head is rotated to separate the sampling needle head from the support plate, then the air exhaust sleeve is rotated to separate the air exhaust sleeve from the second threaded ring, at the moment, the pushing mechanism and the sampling sleeve can be taken down, when secondary sampling is required, the pushing mechanism is cleaned firstly, after cleaning, the pushing mechanism is inserted into the support plate, a new sampling sleeve is placed on the pushing mechanism, then the air exhaust sleeve is screwed on the second threaded ring, the pushing mechanism and the sampling sleeve are fixed on the support plate through the air exhaust sleeve, and then the new sampling needle head is screwed on the first threaded ring.
(4) According to the invention, the first dust screen and the second dust screen are arranged, and both the first dust screen and the second dust screen have a blocking effect on dust in the air, so that the dust is prevented from being accumulated in the air exhaust sleeve, the air exhaust plate is easy to block, and meanwhile, the dust is prevented from entering the sampling sleeve through the air hole through the third dust screen.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is an enlarged view taken at A of FIG. 1 in accordance with the present invention;
FIG. 3 is a cross-sectional view taken at B-B of FIG. 1 in accordance with the present invention;
FIG. 4 is a front view of the structure of the present invention;
FIG. 5 is a side view of the structure of the present invention;
FIG. 6 is a bottom view of the structure of the present invention;
FIG. 7 is a front view of a sampling sleeve of the present invention;
FIG. 8 is a bottom view of the suction sleeve of the present invention;
FIG. 9 is a side view of the connector block of the present invention;
fig. 10 is a front view of the sealing mechanism of the present invention.
In the figure: 1. a support plate; 2. a first threaded ring; 3. a sampling needle; 4. a pushing mechanism; 41. a first straight pipe; 42. a first baffle plate; 43. a first spring; 44. a second baffle; 45. a second straight pipe; 5. a third straight pipe; 6. a sealing cover; 7. a sampling sleeve; 8. connecting blocks; 9. a second threaded ring; 10. an air extraction sleeve; 11. an air extraction mechanism; 111. an air extraction plate; 112. connecting columns; 113. a handle plate; 114. a support ring; 115. fixing a column; 12. an air tank; 13. a limiting ring; 14. a sealing mechanism; 141. a fourth straight pipe; 142. bending the pipe; 143. a first fixing plate; 144. a second fixing plate; 145. a second spring; 146. a slide plate; 147. a bumping post; 148. a sealing plate; 149. sealing the column; 15. a third baffle plate; 16. air holes; 17. pulling the ring; 18. a groove; 19. a graduated scale; 20. a first dust screen; 21. a second dust screen; 22. and a third dust prevention net.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
Referring to fig. 1-10, a cell diagnosis uses quantitative sampling device, including backup pad 1, the bottom fixedly connected with first screw ring 2 of backup pad 1, the inner wall threaded connection of first screw ring 2 has a sample syringe needle 3, through first screw ring 2, make backup pad 1 and sample syringe needle 3 threaded connection together, and then the person of being convenient for use changes sample syringe needle 3, the upper surface of backup pad 1 is provided with pushing mechanism 4, the inner wall of backup pad 1 and the inner wall of sample syringe needle 3 all with pushing mechanism 4's sliding surface connection, 4 inner wall sliding connection of pushing mechanism has third straight tube 5, the outer fixed surface of third straight tube 5 is connected with sealed lid 6, the outer surface threaded connection of sealed lid 6 has a sample sleeve 7, sample sleeve 7 is the clear glass sleeve, fix third straight tube 5 on sample sleeve 7 through sealed lid 6.
Equal sliding connection in the left and right sides of sampling sleeve 7 has connecting block 8, the bottom of connecting block 8 and the last fixed surface of backup pad 1 are connected, the last fixed surface of connecting block 8 is connected with second screw ring 9, link together backup pad 1 and second screw ring 9 through connecting block 8, the inner wall threaded connection of second screw ring 9 has air exhaust sleeve 10, rotate air exhaust sleeve 10, make air exhaust sleeve 10 reciprocate through second screw ring 9, air exhaust sleeve 10's surface and sampling sleeve 7's inner wall sliding connection, recess 18 has been seted up in air exhaust sleeve 10's front, recess 18's inner wall fixedly connected with scale 19, scale 19's front and second screw ring 9's inner wall sliding connection, through setting up scale 19, convenient to use person observes the position of second screw ring 9.
An air extracting mechanism 11 is fixedly connected to the inner wall of the air extracting sleeve 10, an air groove 12 is formed in the bottom of the air extracting sleeve 10, air below the air extracting mechanism 11 circulates through the air groove 12, a limiting ring 13 is fixedly connected to the inner wall of the sampling sleeve 7, the upper surface of the limiting ring 13 is in contact with the bottom of the air extracting sleeve 10, the limiting ring 13 plays a limiting role in limiting the air extracting sleeve 10, a sealing mechanism 14 is fixedly connected to the inner wall of the sampling sleeve 7, the sealing mechanism 14 is located between the limiting ring 13 and the sealing cover 6, a third baffle 15 is slidably connected to the inner wall of the sampling sleeve 7, the bottom of the third baffle 15 is in contact with the upper surface of the sealing cover 6, the third baffle 15 moves upwards to extract cells into the sampling sleeve 7, air holes 16 are formed in the front side and the rear side of the sampling sleeve 7, the air holes 16 are located in the front side and the rear side of the sealing mechanism, the center of the third dust screen 22 is in the same horizontal plane as the center of the air hole 16.
The pushing mechanism 4 comprises a first straight pipe 41, the inner wall of the support plate 1 and the inner wall of the sampling needle 3 are both connected with the outer surface of the first straight pipe 41 in a sliding manner, the surface of the first straight pipe 41 is fixedly connected with a first baffle plate 42, the bottom of the first baffle plate 42 is in contact with the upper surface of the support plate 1, the upper surface of the first baffle plate 42 is fixedly connected with a first spring 43, the upper surface of the first spring 43 is fixedly connected with a second baffle plate 44, the initial length of the first spring 43 is smaller than the sum of the lengths of the first straight pipe 41 and the second straight pipe 45, the first spring 43 plays a role in pushing the second baffle plate 44, the bottom of the second baffle plate 44 is fixedly connected with a second straight pipe 45, the inner wall of the second straight pipe 45 is connected with the outer surface of the first straight pipe 41 in a sliding manner, the inner wall of the second straight pipe 45 and the inner wall of the second baffle plate 44 are both connected with the outer, the sampling needle 3 is communicated with the third straight pipe 5, the upper surface of the second baffle plate 44 is contacted with the bottom of the sealing cover 6, the weight of the sampling sleeve 7 is measured through the first spring 43, and when the weight of the sampling sleeve 7 is larger than the thrust of the first spring 43 to the second baffle plate 44, the sampling sleeve 7 moves downwards.
The air extracting mechanism 11 comprises an air extracting plate 111, the outer surface of the air extracting plate 111 is in sliding connection with the inner wall of the air extracting sleeve 10, the upper surface of the air extracting plate 111 is fixedly connected with a connecting column 112, the upper surface of the connecting column 112 is fixedly connected with a handle plate 113, the bottom of the handle plate 113 is in contact with the upper surface of the air extracting sleeve 10, the outer surface of the connecting column 112 is in sliding connection with a support ring 114, the support ring 114 plays a guiding role for the connecting column 112, meanwhile, the support ring 114 plays a limiting role for the air extracting plate 111, so that the air extracting plate 111 cannot be separated from the air extracting sleeve 10, the outer surface of the support ring 114 and the inner wall of the air extracting sleeve 10 are both fixedly connected with a fixing column 115, the air extracting plate 111 is positioned above the air groove 12, the bottom of the air extracting plate 111 is provided with a first dust screen 20, the outer, the inner wall of second dust screen 21 and the surface sliding connection of spliced pole 112, the surface of second dust screen 21 and the inner wall fixed connection of the sleeve 10 of bleeding, through setting up first dust screen 20, second dust screen 21, first dust screen 20 and second dust screen 21 all play the effect of blockking to the dust in the air, and then prevent that the dust from piling up in the sleeve 10 of bleeding, lead to the easy card of air exhaust plate 111 to die.
The sealing mechanism 14 comprises a fourth straight pipe 141, the left and right sides of the fourth straight pipe 141 are fixedly communicated with bent pipes 142, the outer surface of the bent pipe 142 is fixedly communicated with a first fixing plate 143, the upper surface of the first fixing plate 143 is fixedly connected with the bottom of the fourth straight pipe 141, the outer surface of the fourth straight pipe 141 is fixedly connected with a second fixing plate 144, the second fixing plate 144 is positioned below the air hole 16, the upper surface of the second fixing plate 144 is fixedly connected with a second spring 145, the upper surface of the second spring 145 is fixedly connected with a sliding plate 146, the sliding plate 146 is positioned above the air hole 16, air between the second fixing plate 144 and the sliding plate 146 is circulated through the air hole 16, meanwhile, through a third dust screen 22, dust is prevented from entering the sampling sleeve 7 through the air hole 16, further, the dust is prevented from being accumulated between the sliding plate 146 and the second fixing plate 144, the inner wall of the sliding plate 146 is, the upper surface of the sliding plate 146 is fixedly connected with a blocking column 147, the upper surface of the blocking column 147 is fixedly connected with a sealing plate 148, the bottom of the sealing plate 148 is in contact with the upper surface of the fourth straight pipe 141, the center of the sealing plate 148 and the center of the fourth straight pipe 141 are on the same vertical line, the diameter of the sealing plate 148 is larger than that of the fourth straight pipe 141, the diameter of the sealing plate 148 is smaller than that of the air exhaust sleeve 10, the upper surface of the sealing plate 148 is fixedly connected with a pull ring 17, a user can pull the sealing plate 148 through the pull ring 17 to open the first straight pipe 41 and the bent pipe 142, so that the user can conveniently place the third baffle 15 and the sealing cover 6 in the sampling sleeve 7 and make the third baffle 15 contact with the sealing cover 6, the bottom of the sealing plate 148 is fixedly connected with a sealing column 149, the left side and the right side of the sealing column 149 are both in sliding connection with one side of the, and the width of the sealing post 149 is larger than the diameter of the bent tube 142, the bent tube 142 is sealed by the sealing post 149.
In the invention, when a user uses the device, firstly, according to the sampling amount, the air suction sleeve 10 is rotated, the thrust of the first spring 43 to the sampling sleeve 7 is adjusted through the limiting ring 13, after the adjustment is finished, the sampling needle 3 is inserted into a cell sample, the handle plate 113 is pulled, the air suction plate 111 moves upwards, at the moment, the air suction plate 111 drives the sliding plate 146 to move upwards, the fourth straight pipe 141 and the bent pipe 142 are opened, then the handle plate 113 is pulled upwards continuously, air below the first fixing plate 143 is sucked into the air suction sleeve 10 through the air suction plate 111, at the moment, the cells are sucked into the sampling sleeve 7 through the third baffle 15, after the cells enter the sampling sleeve 7, the gravity of the sampling sleeve 7 is increased, when the gravity of the sampling sleeve 7 is greater than that of the first spring 43, the sampling sleeve 7 moves downwards, the air groove 12 is opened, at the moment, the air suction plate 111 cannot drive the sliding plate 146 to move upwards continuously, the slide plate 146 is returned to the initial position by the second spring 145, the fourth straight tube 141 and the bent tube 142 are sealed by the sealing plate 148 and the sealing post 149, the amount of air between the third baffle 15 and the first fixing plate 143 cannot be changed, and then stopping the cell extraction, after the sampling is finished, rotating the air extraction sleeve 10 to separate the air extraction sleeve 10 from the second threaded ring 9, the sampling sleeve 7 is then removed, and when a sample needs to be taken again, the pushing mechanism 4 is cleaned first, and after cleaning, the pushing mechanism 4 is inserted into the supporting plate 1, a new sampling sleeve 7 is placed on the pushing mechanism 4, then, the air exhaust sleeve 10 is screwed on the second threaded ring 9, the pushing mechanism 4 and the sampling sleeve 7 are fixed on the support plate 1 through the air exhaust sleeve 10, and then a new sampling needle 3 is screwed on the first threaded ring 2, and at the moment, sampling can be carried out again.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Claims (9)
1. A quantitative sampling device for cell diagnosis comprises a supporting plate (1), and is characterized in that the bottom of the supporting plate (1) is fixedly connected with a first threaded ring (2), the inner wall of the first threaded ring (2) is in threaded connection with a sampling needle (3), the upper surface of the supporting plate (1) is provided with a pushing mechanism (4), the inner wall of the supporting plate (1) and the inner wall of the sampling needle (3) are both in sliding connection with the surface of the pushing mechanism (4), the inner wall of the pushing mechanism (4) is in sliding connection with a third straight pipe (5), the outer surface of the third straight pipe (5) is fixedly connected with a sealing cover (6), and the outer surface of the sealing cover (6) is in threaded connection with a sampling sleeve (7);
the left side and the right side of the sampling sleeve (7) are both connected with connecting blocks (8) in a sliding mode, the bottom of each connecting block (8) is fixedly connected with the upper surface of the corresponding supporting plate (1), the upper surface of each connecting block (8) is fixedly connected with a second threaded ring (9), the inner wall of each second threaded ring (9) is connected with an air exhaust sleeve (10) in a threaded mode, and the outer surface of each air exhaust sleeve (10) is connected with the inner wall of the sampling sleeve (7) in a sliding mode;
air exhaust sleeve's (10) inner wall fixedly connected with air exhaust mechanism (11), air groove (12) have been seted up to the bottom of air exhaust sleeve (10), the inner wall fixedly connected with spacing ring (13) of sampling sleeve (7), the upper surface of spacing ring (13) and the bottom contact of air exhaust sleeve (10), the inner wall fixedly connected with sealing mechanism (14) of sampling sleeve (7), sealing mechanism (14) are located between spacing ring (13) and sealed lid (6), the inner wall sliding connection of sampling sleeve (7) has third baffle (15), the bottom of third baffle (15) and the upper surface contact of sealed lid (6), gas pocket (16) have all been seted up to both sides around sampling sleeve (7), gas pocket (16) are located both sides around sealing mechanism (14).
2. The quantitative sampling device for cell diagnosis according to claim 1, wherein the pushing mechanism (4) comprises a first straight tube (41), the inner wall of the support plate (1) and the inner wall of the sampling needle (3) are both slidably connected with the outer surface of the first straight tube (41), a first baffle (42) is fixedly connected to the surface of the first straight tube (41), the bottom of the first baffle (42) is in contact with the upper surface of the support plate (1), a first spring (43) is fixedly connected to the upper surface of the first baffle (42), a second baffle (44) is fixedly connected to the upper surface of the first spring (43), a second straight tube (45) is fixedly connected to the bottom of the second baffle (44), the inner wall of the second straight tube (45) is slidably connected with the outer surface of the first straight tube (41), the inner wall of the second straight tube (45) and the inner wall of the second baffle (44) are both slidably connected with the outer surface of the third straight tube (5), the upper surface of the second baffle (44) is in contact with the bottom of the sealing cover (6).
3. The quantitative sampling device for cell diagnosis according to claim 1, wherein the air pumping mechanism (11) comprises an air pumping plate (111), the outer surface of the air pumping plate (111) is slidably connected with the inner wall of the air pumping sleeve (10), the upper surface of the air pumping plate (111) is fixedly connected with a connecting column (112), the upper surface of the connecting column (112) is fixedly connected with a handle plate (113), the bottom of the handle plate (113) is in contact with the upper surface of the air pumping sleeve (10), the outer surface of the connecting column (112) is slidably connected with a support ring (114), the outer surface of the support ring (114) and the inner wall of the air pumping sleeve (10) are both fixedly connected with fixing columns (115), and the air pumping plate (111) is located above the air groove (12).
4. The quantitative sampling device for cell diagnosis according to claim 1, wherein the sealing mechanism (14) comprises a fourth straight tube (141), the left and right sides of the fourth straight tube (141) are fixedly communicated with bent tubes (142), the outer surface of the bent tube (142) is fixedly communicated with a first fixing plate (143), the upper surface of the first fixing plate (143) is fixedly connected with the bottom of the fourth straight tube (141), the outer surface of the fourth straight tube (141) is fixedly connected with a second fixing plate (144), the second fixing plate (144) is located below the air hole (16), the upper surface of the second fixing plate (144) is fixedly connected with a second spring (145), the upper surface of the second spring (145) is fixedly connected with a sliding plate (146), the sliding plate (146) is located above the air hole (16), the inner wall of the sliding plate (146) is fixedly connected with the outer surface of the fourth straight tube (141), the upper surface of slide plate (146) fixedly connected with fender post (147), the upper surface fixed connection of fender post (147) has sealing plate (148), the bottom of sealing plate (148) and the upper surface contact of fourth straight tube (141), the bottom fixedly connected with sealing post (149) of sealing plate (148), the left and right sides of sealing post (149) all with return bend (142) be close to one side sliding connection of sealing post (149).
5. The quantitative sampling device for cytodiagnosis according to claim 4, wherein said sealing pillar (149) is a regular quadrangular prism, and the width of the sealing pillar (149) is larger than the diameter of the bent tube (142).
6. The quantitative sampling device for cell diagnosis according to claim 4, wherein a pull ring (17) is fixedly attached to the upper surface of the sealing plate (148).
7. The quantitative sampling device for cytodiagnosis as claimed in claim 1, wherein the front face of the air exhaust sleeve (10) is provided with a groove (18), the inner wall of the groove (18) is fixedly connected with a graduated scale (19), and the front face of the graduated scale (19) is slidably connected with the inner wall of the second threaded ring (9).
8. The quantitative sampling device for cell diagnosis according to claim 3, wherein a first dust screen (20) is disposed at the bottom of the air extraction plate (111), the outer surface of the first dust screen (20) is fixedly connected with the inner wall of the air extraction sleeve (10), a second dust screen (21) is disposed above the support ring (114), the inner wall of the second dust screen (21) is slidably connected with the outer surface of the connection column (112), and the outer surface of the second dust screen (21) is fixedly connected with the inner wall of the air extraction sleeve (10).
9. The quantitative sampling device for cytodiagnosis according to claim 1, wherein a third dust-proof net (22) is fixedly connected to both the front and rear sides of the sampling sleeve (7), and the center of the third dust-proof net (22) and the center of the air hole (16) are in the same horizontal plane.
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| CN201911151867.6A CN110646233B (en) | 2019-11-22 | 2019-11-22 | Cell diagnosis is with quantitative sampling device |
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| CN201911151867.6A CN110646233B (en) | 2019-11-22 | 2019-11-22 | Cell diagnosis is with quantitative sampling device |
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| CN110646233B true CN110646233B (en) | 2020-04-07 |
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| CN114252542A (en) * | 2021-11-19 | 2022-03-29 | 贵阳学院 | Universal gas chromatography sample injector |
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| DE3310032C2 (en) * | 1983-03-19 | 1985-06-13 | Dr. H. Tiefenbach Gmbh & Co, 4300 Essen | Submersible siphon for taking liquid samples, especially water samples from waters of great depth |
| AU8746598A (en) * | 1997-09-10 | 1999-03-29 | Benny Gaber | Tissue collector |
| CN201139587Y (en) * | 2008-01-11 | 2008-10-29 | 王卫国 | Ring tection inhalation type soft tissue biopsy sampling needle |
| KR20140006918A (en) * | 2011-04-11 | 2014-01-16 | 롱샨 리 | Multifunction aspiration biopsy device and methods of use |
| SG11201402149TA (en) * | 2011-11-08 | 2014-06-27 | Auxocell Lab Inc | Systems and methods for processing cells |
| CN105092279B (en) * | 2014-05-21 | 2019-09-24 | 艾博生物医药(杭州)有限公司 | A kind of sample collection device |
| CN104833558B (en) * | 2015-03-25 | 2017-11-03 | 中国人民解放军第三军医大学第一附属医院 | Parathyroid gland is homogenized destroyer |
| CN205072913U (en) * | 2015-10-27 | 2016-03-09 | 郑州人民医院 | Tumour sampler |
| CN207520156U (en) * | 2017-04-20 | 2018-06-22 | 何俊峰 | A kind of needle inhales cell sampler |
| CN207439746U (en) * | 2017-10-10 | 2018-06-01 | 深圳市人民医院 | A kind of Medical detection sample filling apparatus |
| CN107988208A (en) * | 2017-12-26 | 2018-05-04 | 东莞赛尔生物科技有限公司 | For extracting the sampler and sampling method of sample from FFPE histotomies |
| CN108671274A (en) * | 2018-04-08 | 2018-10-19 | 无锡市人民医院 | A kind of dept. of dermatology's malignant pustule draw-out device |
| CN108542436B (en) * | 2018-05-21 | 2023-04-28 | 北京大学 | Suction injector for quantitatively sucking liquid and control method thereof |
| CN209570370U (en) * | 2019-01-08 | 2019-11-01 | 辽阳职业技术学院 | One kind being used for solid food nutrition sampling cylinder |
| CN109820547A (en) * | 2019-04-16 | 2019-05-31 | 刘华 | A kind of paediatrics kidney puncture needle |
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