CN105092279B - A kind of sample collection device - Google Patents
A kind of sample collection device Download PDFInfo
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- CN105092279B CN105092279B CN201410214560.7A CN201410214560A CN105092279B CN 105092279 B CN105092279 B CN 105092279B CN 201410214560 A CN201410214560 A CN 201410214560A CN 105092279 B CN105092279 B CN 105092279B
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- receiving flask
- bar
- bottle body
- sample collection
- collection device
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Abstract
The present invention relates to a kind of sample collection device, the bottle body including both ends open, wherein the coverd part open at one end of receiving flask seals, and another end opening is sealed by sample collection bar;The device further includes preventing the structure that liquid flows out in receiving flask body.Sample collection device of the invention is provided with the structure for preventing automatic discharging function, can effectively prevent the liquid in receiving flask from voluntarily flowing out, avoid operator and be contaminated by the sample;Simultaneously, it is therefore prevented that the reduction of the amount of liquid sample guarantees going on smoothly for detection.
Description
Technical field
The present invention relates to a kind of devices of sample collection, carry out the sample collection of diluted sample in particular for buffer solution
Device.
Background technique
Following background technique is used to help reader and understands the present invention, and is not construed as the prior art.
Currently, collecting and storing the device of liquid, solid or semi-solid samples, including for sample of defecating in immunoassay
This collection device, is that medical institutions are commonly used in the daily work.Many testing agencies are also required to using to such receipts
Acquisition means, especially for the collection of the various in vitro samples of human body.Also, many solid or semisolid samples directly into
When row detection, because Yi Gan or be unevenly distributed due to cause testing result inaccurate.Therefore, it requires to carry out before receiving detection pre-
It is first handled, for example, dissolution or dilution etc..
There are many collection devices using at present, such as: patent US7048693, which provides one kind, can collect biological sample
This device its advantage is that fresh sample can be saved, and can carry out pre-treatment to sample, and be stored in collection dress
Sample in setting can be transported.
In addition, Chinese patent 200420092463.7 also illustrate it is a kind of it is novel adopt closet, collect stick and be connected with lid,
And enter in the bottle equipped with dilution after acquiring stool sampl, then design has outlet discharge from lid.Outlet is set
Meter lid is sealed against.
In addition, improved patent ZL 200620107736.X describes another novel acquisition and collects the dress of sample
It sets, in the collector that buffer is all open mounted in both ends, is sent into stool sampl from open at one end with bar is collected, and simultaneously
Seal this opening of collector.When needing to detect sample, mixed sample is taken out from the other end, is detected.?
In practical operation, (usually bottle body is compressible, and compression bottle body arranges liquid for taking-up from device again after sample mixing
During out), liquid can flow out after lid opening, cause operator contaminated.
Summary of the invention
The present invention provides a kind of improved sample collection device, which can guarantee that the liquid in receiving flask exists
When operator does not operate, liquid will not voluntarily flow out in bottle.It is collected in bottle to effectively avoid operator
Liquid pollution.
Sample collection device provided by the invention, the bottle body including both ends open, wherein the open at one end of receiving flask is covered
Body sealing, another end opening are sealed by sample collection bar;Also, the device further includes preventing the knot that liquid flows out in receiving flask body
Structure.
The structure for preventing receiving flask body fluid body from flowing out in one preferred embodiment includes open at one end positioned at receiving flask
The choke tube at place.Prevent liquid from going out along bottle body opening fair current by choke tube.
In one specific embodiment, choke tube is conical structure.
More preferably in mode, which is inverted in the place open at one end for collecting bottle body.
In another specific embodiment, one end of the bottle body with choke tube is cone shape, and opening is located at circular cone
The liquid in bottle body is discharged by the opening in the top of body.
One more preferably in embodiment, the conical direction of choke tube and the cone shape direction of receiving flask one end
On the contrary.
It is set as cone shape in the one end (one end connecting with lid) for collecting bottle body, and is opened on the top of cone shape
Mouthful, it is to allow the liquid to be discharged from receiving flask as requested to be controlled liquid when flowing out from receiving flask;But
In practical operation, effect be not it is especially desirable, have liquid just can voluntarily flow out after lid opening, and in the cone shaped opening
After place increases inverted conical shape pipe, for liquid in the bottle mouth position for flowing to receiving flask, because fluid channel becomes smaller, liquid flow to bottle
It is obstructed, is reduced to flow over the liquid come, the amount of liquid for being stored in bottle body opening is reduced at mouthful;Therefore sufficient amount is not had
Liquid accumulated in bottle mouth position, in the case where receiving flask is by sealing state to after opening, there will be no remain in the liquid of bottleneck without
Operation is just voluntarily flowed out.
On the other hand, the present invention also provides another kinds to prevent the structure that liquid flows out in bottle, which includes being located to collect
Groove on bar.
In one preferred embodiment, the groove is positioned at the hollow shrinkage pool collected on bar.
In a particular embodiment, the structure (prevent liquid from flowing out structure) for collecting the groove or shrinkage pool on bar can be with
The choke tube at receiving flask place open at one end is used cooperatively, and also can be used alone in the structure of receiving flask.
In some specific embodiments, groove or shrinkage pool are located at the middle part for collecting bar.
In other embodiments, the other end opening of bottle body has a spacer body, which matches with bar is collected
Close another end opening of sealing receiving flask.
In one preferred embodiment, it is no more than positioned at groove or the shrinkage pool fluting or position of opening collected in the middle part of bar and receives
At the cooperation sealing receiving flask position for collecting bar and spacer body.It both ensure that collect bar and spacer body leads to before sealing receiving flask in this way
It crosses the shrinkage pool collected on bar to communicate with the outside world, passes to air pressure mutually and guarantee that inside and outside air pressure is identical;Guarantee again when collect bar with
Sealing function can be effectively played when spacer body cooperation sealing receiving flask.
Liquid can voluntarily flow out after the receiving flask opening being commonly designed is opened, to find out its cause, there are a pressure differences
Reason, it is generally the case that collect bar one end (front end) enter receiving flask in when, receiving flask inner cavity i.e. can be sealed,
Therefore, the air in receiving flask is compressed (space is fixed size) because collecting the addition of bar, thus air pressure opposite outer
Increase for air pressure.I.e. in the bottle body of air pressure balance, a part of addition because collecting bar makes the space of air is opposite to reduce,
To which air pressure increases.And after air pressure increases in bottle body, it will lead to the bottle body of sealing after opening is open at one end, liquid passes through opening
It voluntarily flows out at place.Therefore, the air pressure reduced in receiving flask effectively can prevent or prevent the liquid in receiving flask from from flowing out.
Groove is set on collecting bar, the volume for collecting bar can be reduced, thus reduce the air pressure in receiving flask, it can
Effectively prevent the outflow of liquid.
It more preferably in mode, collects and hollow shrinkage pool is set on bar, make to collect process of the bar in insertion receiving flask
In be connected to by shrinkage pool with extraneous holding, when being entirely insertable in receiving flask until collecting bar, collection bar while sealing receiving flask, this
Sample, after sealing, internal air pressure is identical as ambient pressure for receiving flask, in this way, after another end opening of receiving flask is opened,
Because of inside and outside air pressure balance, liquid will not voluntarily be flowed out because of pressure.
In some embodiments, the one end for collecting bar has spiral groove.Receipts are stored by these spiral grooves
The sample of collection, and these samples are brought into receiving flask.
In one preferred embodiment, the other end for collecting bar is connected with a lid, and cover cap conjunction is being collected
Another open end of bottle.The lid seals receiving flask while lid closes receiving flask.
In some specific embodiments, collecting bottle body material includes compressible material.
In one preferred embodiment, the material of the collection bottle body is squeezable plastic material.
Beneficial effect
Sample collection device of the invention is provided with the structure for preventing automatic discharging function, can effectively prevent receiving flask
Interior liquid voluntarily flows out, and avoids operator and is contaminated by the sample;Simultaneously, it is therefore prevented that the reduction of the amount of liquid sample guarantees inspection
That surveys goes on smoothly.
Detailed description of the invention
Fig. 1 is the schematic diagram of a sample collection device of the invention;
Diagrammatic cross-section before the sample collection device improvement that Fig. 2 is Fig. 1;
Fig. 3 is the improved diagrammatic cross-section of sample collection device of Fig. 1;
Fig. 4 is a component of collection device of the present invention --- collect the schematic diagram of bottle body;
Fig. 5 is Fig. 4 component --- receiving flask structural reform is into preceding diagrammatic cross-section;
Fig. 6 is Fig. 4 component --- receiving flask structural reform is into preceding diagrammatic cross-section;
Fig. 7 is another component of sample collection device of the invention --- showing before collecting bar (being connected with lid) improvement
It is intended to;
Fig. 8 is the diagrammatic cross-section of Fig. 7;
Fig. 9 is another component of sample collection device of the invention --- collection bar (being connected with lid) is improved to be shown
It is intended to;
Figure 10 is the diagrammatic cross-section of Fig. 9.
Description of symbols:
Sample collection device 800;Collect bottle body 100;Upper cover body 200;Lower cover 300;Collect bar 400;Spacer body 500;
Collect the upper port 101 of bottle body;Choke tube 102;Bottle body external screw thread 103;Collect the lower port 104 of bottle body;Spiral shell in receiving flask body
Line 105;Upper cover intracoelomic cavity plug 201;Upper cover body internal screw thread 202;Lower cover screw thread 301;Collect bar one end 402;It collects on bar
End 401;It collects 403 in the middle part of bar;Collect bar one end spiral groove 404;Collect shrinkage pool 405 in the middle part of bar;The hollow hole of spacer body
501。
Specific embodiment
Sample
Signified sample of the invention refers to that those can be used to detect, chemically examine or diagnose with the presence or absence of interested analyte
The substance of matter., sample can be, for example, liquid sample, solid sample and semisolid sample, liquid sample may include blood, blood
Slurry, serum, urine, saliva and various juices.Solid sample may include excrement, soil and organism organ-tissue.It collects
The sample come can be used for the methods of immune detection, chemical detection, enzyme detection to detect whether that there are analytes.
The top and bottom of receiving flask
Top and bottom, which refer to relative to the position for collecting bar bar and bottle cap, defines the location of bottle body different openings,
However, it is not limited to this.The lower end open at one end for being known as bottle body for the bottle body being connected with collection bar will be connected by we with bottle cap
Bottle body it is open at one end be known as bottle body upper end.
Collect bar
One end 402 of bar 400 is collected for collecting sample, which can be spiral shape, stick, hollow tubular, dispersion
Aperture or key shape etc., preferred spiral shape is conducive to the adherency of sample.When collecting sample, such as acquisition excrement
Sample can be attached in the groove 404 of screw thread by sample, screwed collection bar, retain sample to greatest extent.It collects
Bar 400 can be connected with a lid (lower cover 300), and the lower end of bottle body is collected in common sealing.Collect the lower cover on bar 400
Body 300 can have much with the mode that bottle body is connected is collected: can be threaded connection, be also possible to plug-in type or buckle closure
Formula.It is preferred that being threadedly coupled, matched by the external screw thread 301 of lower cover with the internal screw thread 105 of bodies top inner cavity, makes to collect bar
400 reach closed state with bottle body 100 is collected, and no matter guarantee sample not from originally during sample collection, storage and transport
It is overflowed at the top of body, causes environmental pollution and inconvenience.
Collect bottle body
100 both ends opens of bottle body-upper end opening 101 and lower ending opening 104 are collected, and is equipped with and bottle body is divided into two
The spacer body 500 divided.
The shape of bottle body 100 can be cylinder, cone, rectangle, combination of different shapes or be transformed to not advise
Form then.The material of bottle body is the material that can be extruded, and in a specific embodiment, bottle body material can be plastics.It adopts
The material for using plastics as bottle body be it is preferred, advantage is 1. visualizations, it can be seen that the disposition of sample in bottle body, favorably
In the accuracy of pattern detection;2. can squeeze bottle body when shifting sample, the sample of processing light can be obtained
Flow into detection zone;3. at low cost.The upper port of bottle body can be cone, smooth opening, be recessed inwardly or the dropper of protrusion
Shape.If the smooth opening of bottle body upper port, can in addition be arranged can by treated sample is guided to the device of detection zone, can such as pull out
Slotting piston.It is preferred that the dropper shape of protrusion, by the dropper shaped opening of protrusion, treated, and sample can flow directly into detection
Area, and reaching closed state with upper cover body 200 will not be such that sample leaks.
In the production process, spacer body 500 can be linked together with bottle body 100, can also be separated with bottle body 100.It is preferred that
Mode in, spacer body 500 is separated with bottle body 100, its advantage is that spacer body 500 can be taken out, will handle the solution dress of sample
Into bottle body 100.Different according to the shape of bottle body 100,500 shape of spacer body should change therewith, guarantee spacer body edge and bottle
It can achieve closed state between internal side wall.The material preferred rubber of spacer body 500.
It include an aperture 501 among spacer body, hole is changeable, which can allow the upper end for collecting bar in
Portion passes through, and is finally formed and is sealed with the one end for collecting bar, the intracorporal sample of bottle and buffer solution are sealed.
Preferably combination is ontology for cylinder to bottle body 100, and spacer body 500 is annular shape, among annular and separation body there are
Hole, hole is changeable, can preferably make to collect the size that bar 400 passes through.The advantages of above-mentioned preferred combination, is: collecting bar
After 400 acquisition fecal samples, collects the insertion of bar 400 and collect in bottle body 100, the sample in the spiral groove 404 for collecting bar
Originally with bar 400 is collected together in the arrival collection bottle body 100 of spacer body 500, the lower cover 300 on collection bar 400 is therewith
With bottle body 100 by threaded closure, the aperture 501 of the upper end 401 and spacer body 500 of collecting bar 400, which is formed, to be closed, in this way,
Collecting bar includes that the sample in thread groove enters sample process region, and extra sample then stays in spacer body 500 and upper cover body
In the region of sealing between 300, both ensure that the collection capacity of sample be unlikely to it is very few and can not correct testing result, also guarantee
Will not because of sample amount it is excessive and be unable to fully processing sample, equally cause the error of testing result, meanwhile, not will cause
Pollution of the extra sample to environment or tester.Solution in bottle body can be a kind of solution for dispersing sample, can be
The different sample process solution such as the treatment fluid containing preservative.
Upper cover body
Upper cover body can be upright, and after bottle body 100 is connect with upper cover body 200, whole device can be upright.200 bottom of upper cover body
The shape in portion can be disk or bracket etc., preferably disk.Disk can increase planarization and stability, make the stabilization of device
Property is more preferable.With the plug 201 that can be sealed with 100 upper end opening 101 of bottle body, the form of plug 201 in 200 inner cavity of upper cover body
Can be cylindrical perhaps cone etc. can be protrusion or recess, and concrete shape is according to collecting bottle body bottom opening
Shape determine.With the structure that can form closed state with bottle body body 100 in the inner cavity of upper cover body, this structure can be with
It is screw thread or buckle etc., preferably screw thread.Internal screw thread 202 is arranged in the inner cavity of upper cover body, meanwhile, it is set at 100 upper end opening of bottle body
External screw thread 103 is set, better sealing effect is reached by the cooperation of screw thread.
Structure of the present invention or technical term used in these are described further below.Following detailed
In thin description, the subsidiary reference word of legend is a part here, it can be actable specific to illustrate the present invention
The mode of concrete scheme illustrates.The present invention, which is not precluded, in we can also carry out other concrete schemes and without prejudice to this hair
Change structure of the invention in the case where bright use scope.
As shown in Figure 1, sample collection device 800 of the invention includes collecting bottle body 100 and upper cover body 200 and lower cover
300, wherein the lid of upper cover body 200 merges the upper end opening 101 that bottle body is collected in sealing, and the lid of lower cover 300 merges sealing and collects bottle body
Lower ending opening 104;Fig. 2 and Fig. 3 is the diagrammatic cross-section of the receiving flask of the equal coverd part sealing in both ends.
Fig. 4, Fig. 5 and Fig. 6 are the schematic diagram for collecting bottle body 100, as shown in the figure, collect the upper end opening of bottle body 100
For the structure of conical cylinder, there is opening 101 on the top of conical cylinder, the upper end for collecting bottle body will be received by the opening 101
Liquid in collection bottle 100 is discharged to outside receiving flask 100.There is external screw thread 103 in the junction of receiving flask cone shape upper port,
The external screw thread 103 is used to collect the upper port 101 of bottle body with the cooperation sealing of the internal screw thread 202 of upper cover body inner chamber body.Collect bottle body
Lower port 104 be cylindrical opening, equally include screw thread 105 in the cylindrical inside, on the screw thread 105 and lower cover
Screw thread 301 cooperation sealing collect bottle body lower ending opening 104.It is collecting in bottle body 100, is including a spacer body 500, it should
Spacer body 500 is located near the lower port 104 for collecting bottle body, for collecting the lower port of bottle body with the collection cooperation sealing of bar 400
104.At the middle part of spacer body 500, the through-hole 501 collecting the support rod of bar and passing through is accommodated with one.One preferred implementation
Example in, receiving flask cone upper port 101, it is interior it is intracavitary have a choke tube 102, as shown in Fig. 6 diagrammatic cross-section, should
Choke tube 102 is cone, is inverted in 101 inner cavity of port, the i.e. circle in the conical direction of the choke tube 102 and upper port 101
Bore the contrary of cylinder.After the choke tube 102, before liquid reaches at upper port 101, need to flow through the choke tube
102, that is, it is introduced into the small port of choke tube 102, to limit the flow velocity and flow of liquid, prevents liquid from bulk deposition
At the upper port 101 of receiving flask, also avoiding upper port 101 just has the phenomenon that liquid outflow in rigid open.
Another structure for preventing liquid from flowing out of collection device 800 of the present invention, which is located at, collects on bar 400.Such as Fig. 7 and Fig. 8
Shown, common collection bar 400 is made of hand part connection support bar part, is had in one end of support rod 402 and is lifted
The spiral groove 404 of sample.And the structure for preventing liquid from flowing out is exactly the groove positioned in the middle part of support rod 403, is more highly preferred to
Embodiment in, the groove be it is hollow, become shrinkage pool 405.As shown in figs. 9 and 10.The position position of the shrinkage pool 405
In the middle part 403 for collecting bar, 405 length of shrinkage pool, which is subject to, is no more than the length for collecting in the middle part of bar 403.One preferably embodiment
In, the open at one end and spiral groove 404 of shrinkage pool 405 are neighbouring, and the other end is no more than the cooperation position for collecting bar and spacer body
At place-collection bar upper end 401, as shown in Figure 3.In such manner, it is possible to guarantee close in collection bar 400 and the cooperation of spacer body 500
Envelope.
As shown in Fig. 2, the sealing in order to guarantee upper port 101, in the inner cavity top of upper cover body 200, including a plug
201, which is linked together with upper cover body 200.Meanwhile the phase of the size of the plug 201 and receiving flask upper end opening 101
It is mating and seal.In one specific embodiment, 101 hole of receiving flask upper end opening is circle, then plug 201 is cylinder accordingly
Shape, and the internal diameter in circular open hole 101 is identical as the cylindrical outer diameter of plug 201.Likewise, as shown in figure 3, the upper cover
Plug 201 on body is located at the lower part of the choke tube 102 inside bottle body when sealing receiving flask upper port 101.Receiving flask
The external screw thread and the intracorporal internal screw thread in upper cover body inner cavity of body are mutually matched relationship, when upper cover body lid is closed to the upper end of receiving flask
When, upper cover body all covers the conical sections of receiving flask, and plug enters the opening of upper end and seals cover gab, meanwhile, on
The internal screw thread of lid and the external screw thread on receiving flask top are mutually twisted, also, the upper end of upper cover body sealing receiving flask.
As shown in figure 3, the lower port 104 for collecting bottle body has two resealings, first by collecting bar 400 and collecting bottle body
The mutual cooperation of interior spacer body 500 is sealed, and is closed to arrive secondly by the lid of lower cover 300 for being located at collection bar one end 401 and be received
It is sealed on collection bottle body 100.Specifically, the insertion of one end 402 collection bottle body 100 that bar 400 is not connected with lower cover 300 is collected
In, which is placed through the through-hole 501 for collecting the spacer body in bottle body 100, and continues to travel downwardly, in downlink
In the process, the shrinkage pool 405 for collecting bar middle part 402 is passed through from the through-hole 501 of spacer body, is passed through inside bottle body 100 at this point, collecting
The shrinkage pool 501 communicates with the outside world, and the inside and outside air pressure of receiving flask 100 communicates and identical.Upper end 401 until collecting bar 400
When place reaches in the hole 501 of spacer body, the upper end 401 for collecting bar seals hole 501, and 100 inside and outside of receiving flask is no longer identical, but
The air pressure of inside and outside is roughly the same, in this way, effectively preventing the liquid in receiving flask 100 because the relationship of air pressure is in upper cover body 200
The case where being flowed out automatically from upper port 101 after being opened.During collection bar 400 moves downward in receiving flask 100, position
The lower port 104 closed to bottle body is collected also is covered in collecting the lower cover 300 on bar, at this point, being located at the spiral shell of receiving flask inner wall
The screw thread 301 of the outer wall of line 105 and lower cover cooperates, and realizes the sealing of receiving flask lower port 401.
Claims (10)
1. a kind of sample collection device, the bottle body including both ends open, wherein the coverd part open at one end of receiving flask seals, separately
It is open at one end to be sealed by sample collection bar;It is characterized in that, the device further includes preventing the structure that liquid flows out in receiving flask body;
The structure for preventing liquid outflow in receiving flask body includes extending back to the collection bottle body from receiving flask is open at one end
Interior intracavitary choke tube;The choke tube is conical structure;The cone choke tube, which is inverted in, collects the open at one end of bottle body
Place;One end of the bottle body with choke tube is cone shape, and opening is located at the top of cone, is discharged and is received by the opening
Collect the liquid in bottle body;The conical direction of choke tube is contrary with the cone shape of receiving flask one end.
2. sample collection device according to claim 1, which is characterized in that described to prevent the knot that liquid flows out in receiving flask
Structure includes positioned at the groove collected on bar.
3. sample collection device according to claim 2, which is characterized in that the groove be positioned at collect bar in
Empty shrinkage pool.
4. sample collection device according to claim 2 or 3, which is characterized in that the groove or shrinkage pool are located at collection bar
Middle part.
5. sample collection device according to claim 4, which is characterized in that the other end opening of bottle body has one point
Spacer, the spacer body and another end opening for collecting bar cooperation sealing receiving flask.
6. sample collection device according to claim 5, which is characterized in that described to be located at the groove or recessed collected in the middle part of bar
Hole fluting or position of opening are no more than at the cooperation sealing receiving flask position for collecting bar and spacer body.
7. sample collection device according to claim 2, which is characterized in that the one end for collecting bar has spiral groove.
8. sample collection device according to claim 7, which is characterized in that the other end for collecting bar is connected with a lid
It connects, which closes in another open end of receiving flask.
9. sample collection device according to claim 1, which is characterized in that the collection bottle body material includes compressible material
Matter.
10. sample collection device according to claim 9, which is characterized in that the material of the collection bottle body is squeezable
Plastic material.
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CN105092279B true CN105092279B (en) | 2019-09-24 |
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CN108195616A (en) * | 2018-02-24 | 2018-06-22 | 广州市康立明生物科技有限责任公司 | A kind of excrement quantitative sampling device |
CN110646233B (en) * | 2019-11-22 | 2020-04-07 | 广州赛太特生物医学科技有限公司 | Cell diagnosis is with quantitative sampling device |
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CN1094164A (en) * | 1992-12-18 | 1994-10-26 | 荣研化学株式会社 | Be convenient to transport the type feces collection container |
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CN200996897Y (en) * | 2006-09-15 | 2007-12-26 | 艾博生物医药(杭州)有限公司 | Sampler collecting container |
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