CN110638958A - Traditional Chinese medicine composition for improving intestinal health, preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for improving intestinal health, preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for improving intestinal health, a preparation method and application thereof, and relates to the field of traditional Chinese medicine preparations. Specifically, the raw materials of the traditional Chinese medicine composition comprise 20-45 parts of astragalus membranaceus, 18-40 parts of bighead atractylodes rhizome, 13-28 parts of coix seed, 10-30 parts of white hyacinth bean, 10-22 parts of hawthorn, 8-20 parts of malt and 3-10 parts of liquorice. The traditional Chinese medicine composition has the advantages of simple preparation method, short production process flow, convenient product use and the like, can be made into paste by directly adopting a proper amount of cold water, does not need a specific feeding system and equipment, can effectively improve the intestinal health problem, reduces the adverse effect of weaning stress on the intestinal villus structure of piglets, reduces the diarrhea rate, and further improves the breeding benefit.
Description
Technical Field
The invention relates to the field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for improving intestinal health, a preparation method and application thereof.
Background
The most important factor influencing the intestinal health of the piglets is weaning stress, and the important characteristic of the stress after weaning is that after a period of fasting period, the nutrition and physiology of the piglets are characterized in that various organs and physiological functions are not well developed, especially the digestive system is not well developed, the activity of most digestive enzymes is low, and the digestion capability of vegetable protein and starch is insufficient.
The piglet mainly depends on the nutrition of breast milk to meet the growth requirement during the lactation period, after weaning, the food of the piglet is changed into relatively indigestible feed from the breast milk with complete nutrition, the two nutrition sources are completely different, and the high-energy high-protein feed is fed after weaning, the immunization mechanism and the intestinal tract shape of the piglet can be changed to a certain extent, and the change can cause nutrition stress to cause diarrhea and even lead the piglet to die.
Therefore, the stage is the stage with the weakest resistance of the piglets and is also an important stage in the pig raising production process. The stress phenomena of feed intake reduction, digestive dysfunction, diarrhea, growth retardation and the like are often shown in the piglets at the early stage of weaning, so that how to reduce the stress caused to the piglets by weaning, improve the intestinal health of the piglets at the early stage of weaning, and improve the daily feed intake and daily weight gain of the piglets at the early stage of weaning and during reloading becomes a core element for breaking through the existing production efficiency.
In order to solve the problem of feed intake reduction caused by incomplete development of a digestive system, the prior art is to add low protein and amino acid with equal proportion into daily ration to perform compensatory regulation of feed intake, which can improve the feed intake, but the daily ration with low nutrient concentration is easily limited by the volume and emptying condition of the gastrointestinal tract.
The invention discloses a piglet feed disclosed in the patent of 'super-early weaning piglet feed' (with the publication number of CN 100531592C), which contains components such as corn, soybean meal, compound multi-vitamin, compound multi-mineral and the like, has a smell close to that of breast milk, good palatability and can avoid weaning stress, but zinc oxide in the compound multi-mineral is derived from chemical by-products, a plurality of harmful substances are remained, the product quality is difficult to control, the absorption of other trace elements can be influenced, the absorption of copper and iron is unbalanced, the deficiency of the trace elements can be caused, and in addition, excessive zinc can pollute underground water after being excreted by livestock bodies, and the sustainable development of the animal husbandry is hindered.
The invention discloses a preparation method of a composite phagostimulant for improving the feed intake of weaned pigs (No. CN 103829032B), which comprises milk-flavor crispy biscuit powder, beer yeast culture, bile acid salt type emulsifier, glucose oxidase, a composite enzyme preparation, a composite synergist and a carrier, wherein the product technology is not easy to be simulated to cause a large amount of homogeneous products, but the technology is very complicated, different components are added in sequence for dissolving and filtering while stirring, and the temperature and the time are continuously controlled in the preparation process, so that time and manpower and material resources are wasted during production, and the required cost is high.
In view of this, the invention is particularly proposed.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for improving intestinal health, a preparation method and application thereof. The traditional Chinese medicine composition provides a solution for the problem of gastrointestinal tract function reduction of piglets caused by weaning stress.
The invention is realized by the following steps:
in a first aspect, the invention provides a traditional Chinese medicine composition for improving intestinal health, which comprises main materials, wherein the main materials comprise the following components in parts by weight: 20-45 parts of astragalus membranaceus, 18-40 parts of bighead atractylodes rhizome, 13-28 parts of coix seed, 10-30 parts of white hyacinth bean, 10-22 parts of hawthorn, 8-20 parts of malt and 3-10 parts of liquorice.
The traditional Chinese medicine composition can improve the intestinal health problem of piglets, is used for avoiding or reducing the adverse effect of weaning stress on the intestinal villus structure of piglets, improving the intestinal mucosa morphological structure, increasing the intestinal villus absorption area, effectively avoiding the damage of solid feed to the intestinal villus, ensuring the absorption of nutrient substances and energy, reducing the diarrhea rate and reducing the intestinal diseases.
In an optional embodiment, the main material comprises the following components in parts by weight: 38-42 parts of astragalus membranaceus, 28-38 parts of bighead atractylodes rhizome, 16-22 parts of coix seed, 13-22 parts of white hyacinth bean, 12-17 parts of hawthorn, 8-12 parts of malt and 4-6 parts of liquorice.
According to the compatibility principle of traditional Chinese medicines, astragalus and bighead atractylodes rhizome are used as monarch drugs for tonifying qi, invigorating spleen and excreting dampness; the coix seed and the malt are used as ministers to help strengthen the spleen and stomach; fructus crataegi and fructus Hordei Germinatus as adjuvant drugs for invigorating spleen and eliminating dampness; the liquorice is used for tonifying qi, regulating the middle warmer and harmonizing the effects of the other drugs in the recipe.
In an alternative embodiment, the Chinese medicinal composition is prepared by adding an auxiliary material to the main material to enhance the characteristics of the composition, wherein the auxiliary material comprises at least one of a thickening agent, a sweetening agent, a flavoring agent and an acidifying agent.
In an optional embodiment, in each 100 parts of the main material, the auxiliary materials comprise the following components in parts by weight: 0.2-1.0 part of thickening agent, 0.01-0.02 part of sweetening agent, 0.1-0.5 part of flavoring agent and 0.5-2.5 parts of acidifying agent.
In an alternative embodiment, the thickening agent is selected from one or more of hydroxypropyl methylcellulose, xanthan gum and polyvinylpyrrolidone, preferably xanthan gum. The thickening agent is added into the traditional Chinese medicine composition, so that the stability of the traditional Chinese medicine composition can be improved, the composition is easy to dissolve in water and good in viscosity, and does not delaminate after being placed for a long time, and meanwhile, the taste of the traditional Chinese medicine paste is improved, so that the traditional Chinese medicine paste is more exquisite and smooth.
In alternative embodiments, the sweetener comprises sodium saccharin and neotame. The added saccharin sodium and neotame can enable the traditional Chinese medicine composition to better meet the palatability of piglets and meet the physiological requirements of olfactory taste of the piglets, the perception degree of the piglets on the saccharin is higher, the sweetness of the saccharin sodium is 500 times that of cane sugar, the bitter taste of the traditional Chinese medicine composition can be improved by adding a small amount of the saccharin sodium, the appetite of the piglets is improved, the neotame is pure in sweetness, has no bitter taste or other afterbitterness, the sweetness is about 8000 times that of the cane sugar, the palatability of the composition can be improved, the bitter taste and the metallic taste of the saccharin sodium can be covered, and the composition can be compounded with the saccharin sodium to generate a.
In an alternative embodiment, the flavoring agent comprises egg flavoring. The egg essence is added, so that the traditional Chinese medicine composition can emit heavy sweet milk fragrance, the smell of the traditional Chinese medicine composition is closer to that of breast milk, and the traditional Chinese medicine composition plays a food calling role for piglets.
In an alternative embodiment, the acidulant is selected from at least one of calcium citrate, calcium fumarate and calcium acetate, preferably calcium citrate. The acidifying agent is added to reduce the pH value of the traditional Chinese medicine composition, reduce the pH value of the gastrointestinal tract of piglets, improve the activity of digestive enzymes, and improve the gastrointestinal tract microflora, thereby reducing the diarrhea rate of piglets, improving the palatability of the traditional Chinese medicine paste, having acid fragrance and stimulating the ingestion of piglets.
In an alternative embodiment, the Chinese medicinal composition is a Chinese medicinal paste.
In an optional embodiment, the traditional Chinese medicine composition further comprises water, and the mass ratio of the main material to the water is 1: (4-6).
The paste is an ointment containing a large amount of powder, and is usually prepared by grinding the medicine into fine powder, or preparing the medicine into an extract according to the contained effective components by a percolation method or other methods, grinding into fine powder, adding a proper amount of adhesive or wetting agent, stirring uniformly, and mixing into paste. The medicinal paste is mainly used as a protective agent, is mostly externally used, is coated on skin, and has the effects of moisture absorption, dryness, itching relieving and the like; some of them are used as root canal filling materials for root canal treatment. In the application, the traditional Chinese medicine composition is used for internal use, and in view of the pharmacological characteristics of the traditional Chinese medicine, the traditional Chinese medicine paste provided by the embodiment of the invention can improve the gastrointestinal microflora, enhance the immunity of piglets, reduce the occurrence of diseases, reduce the breeding cost and improve the comprehensive breeding benefit.
In alternative embodiments, the Atractylodis rhizoma is pulverized; more preferably, the particle size of the bighead atractylodes rhizome is 80-200 meshes.
In alternative embodiment, the main materials except Atractylodis rhizoma are obtained by parching and micronizing.
In an alternative embodiment, the adjunct is produced by micronizing at least one of a thickener, a sweetener, a flavoring agent and an acidulant.
In a second aspect, the embodiment of the present invention also provides a preparation method of the above traditional Chinese medicine paste for improving intestinal health, which comprises mixing the raw materials of the traditional Chinese medicine composition.
In an alternative embodiment, the method comprises:
pulverizing rhizoma Atractylodis Macrocephalae, and sieving to obtain rhizoma Atractylodis Macrocephalae;
micronizing one or more of thickener, sweetener, flavoring agent and acidifier to obtain adjuvant;
parching and micronizing radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix to obtain radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix respectively;
mixing the obtained white atractylodes rhizome and the auxiliary materials after superfine grinding according to the parts by weight to obtain a first mixture;
mixing the first mixture with radix astragali, semen Coicis, semen lablab album, fructus crataegi, fructus Hordei Germinatus and radix Glycyrrhizae in the above weight parts to obtain the Chinese medicinal composition.
After the medicinal materials provided by the embodiment of the invention are fried, the medicine property is mild, the medicine effect is specific, the efficacy of tonifying qi, strengthening spleen and stomach is stronger, and the piglet feed intake can be obviously improved. After being fried, the raw materials are subjected to superfine grinding, so that the bitter taste of the medicinal materials can be reduced, the product is fine and smooth in taste and good in palatability, and the feed intake of piglets is improved; meanwhile, the starch gelatinization degree in the medicinal materials is improved, and the digestibility of the product is improved. The preparation method is simple, the production process flow is short, the product is convenient to use, the paste can be prepared by directly using a proper amount of cold water, a specific feeding system and equipment are not needed, and the investment of a large amount of manpower and material resources is not added to a pig-raising practitioner.
In an optional embodiment, the step of sieving the bighead atractylodes rhizome raw material is to sieve the bighead atractylodes rhizome raw material by a sieve of 80-200 meshes. Pulverizing Atractylodis rhizoma into 80-200 mesh powder to prevent or reduce the decrease of effective components and avoid the instability of atractylone in Atractylodis rhizoma volatile oil to heat.
In an optional embodiment, the stir-frying time of the stir-fried superfine powder is 15-30 min, and the superfine powder time of the stir-fried superfine powder is 5-30 min.
In a third aspect, the embodiment of the invention also provides the traditional Chinese medicine composition for improving the intestinal health or a preparation method of the traditional Chinese medicine composition for improving the intestinal health, and an application of the prepared traditional Chinese medicine composition for improving the intestinal health in weaned piglets.
The product prepared from the traditional Chinese medicine composition provided by the embodiment of the invention is pure traditional Chinese medicine paste, has no pollution, no residue and no toxic or side effect, conforms to the idea of 'non-antibiotic breeding', can effectively promote the development of animal husbandry healthy breeding, and contributes to the production of green healthy food.
In an optional embodiment, the amount of the traditional Chinese medicine composition for improving the intestinal health is 3-9 g/head.
The invention has the following beneficial effects:
the embodiment of the invention provides a traditional Chinese medicine composition for improving intestinal health, which comprises the following raw materials of 20-45 parts of astragalus membranaceus, 18-40 parts of bighead atractylodes rhizome, 13-28 parts of coix seed, 10-30 parts of white hyacinth bean, 10-22 parts of hawthorn, 8-20 parts of malt and 3-10 parts of liquorice. The traditional Chinese medicine composition takes astragalus and bighead atractylodes rhizome as monarch drugs according to the compatibility principle of traditional Chinese medicines, and the astragalus and the bighead atractylodes rhizome have the effects of tonifying qi, invigorating spleen and excreting dampness; the coix seed and the malt are used as ministers to help strengthen the spleen and stomach; fructus crataegi and fructus Hordei Germinatus as adjuvant drugs for invigorating spleen and eliminating dampness; the composition prepared from the components of the liquorice, the qi tonifying, the middle warmer regulating and the other medicines harmonizing has the effects of improving the problem of gastrointestinal tract function decline of weaned pigs, reducing the adverse effect of weaning stress on intestinal villus structures of the piglets, reducing the diarrhea rate and further improving the culture benefit.
The embodiment of the invention also provides a preparation method of the traditional Chinese medicine composition, and the preparation method comprises the step of mixing the traditional Chinese medicine composition. The preparation method is simple and easy to implement, the production process flow is short, the product is convenient to use, the paste can be prepared by directly using a proper amount of cold water, and the intestinal health problem can be effectively improved without a specific feeding system and equipment.
In addition, the embodiment of the invention provides the application of the traditional Chinese medicine composition for improving the intestinal health or the traditional Chinese medicine composition for improving the intestinal health prepared by the preparation method in weaned pigs.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The traditional Chinese medicine composition for improving the intestinal health comprises main materials, wherein the main materials comprise the following components in parts by weight:
main materials: 40 parts of astragalus, 38 parts of bighead atractylodes rhizome, 22 parts of coix seed, 13 parts of white hyacinth bean, 12 parts of hawthorn, 12 parts of malt and 5 parts of liquorice.
In each 100 parts of the main material, the auxiliary material comprises the following components in parts by weight: 0.3 part of xanthan gum, 0.015 part of saccharin sodium, 0.0018 part of neotame, 0.3 part of egg essence and 1.5 parts of calcium citrate.
The preparation method of the traditional Chinese medicine composition for improving the intestinal health comprises the following steps:
crushing the rhizoma atractylodis macrocephalae raw materials, and sieving the crushed rhizoma atractylodis macrocephalae raw materials by a 200-mesh sieve to obtain rhizoma atractylodis macrocephalae;
parching radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix for 20min and micronizing for 10min to obtain radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix respectively;
micronizing xanthan gum, egg essence and calcium citrate, and mixing saccharin sodium and neotame to obtain adjuvants;
mixing the white atractylodes rhizome and the auxiliary materials according to the parts by weight to obtain a first mixture;
mixing the first mixture with radix astragali, semen Coicis, semen lablab album, fructus crataegi, fructus Hordei Germinatus, and radix Glycyrrhizae in the above weight parts to obtain the Chinese medicinal composition.
Mixing the obtained traditional Chinese medicine composition with cold water according to a mass ratio of 1: 4, mixing to obtain the Chinese medicinal paste.
Example 2
The present embodiment provides a traditional Chinese medicine composition for improving intestinal health and a preparation method thereof, which are substantially the same as those in embodiment 1, except that the parameters are different, specifically as follows:
the traditional Chinese medicine composition for improving the intestinal health comprises the following main materials: 42 parts of astragalus, 40 parts of bighead atractylodes rhizome, 25 parts of coix seed, 18 parts of white hyacinth bean, 10 parts of hawthorn, 15 parts of malt and 8 parts of liquorice.
In each 100 parts of the main material, the auxiliary material comprises the following components in parts by weight: 0.5 part of xanthan gum, 0.020 part of saccharin sodium, 0.001 part of neotame, 0.4 part of egg essence and 2.0 parts of calcium citrate.
The preparation method of the traditional Chinese medicine composition for improving intestinal health provided by the embodiment comprises the following steps:
crushing the rhizoma atractylodis macrocephalae raw materials, and sieving the crushed rhizoma atractylodis macrocephalae raw materials by a 120-mesh sieve to obtain rhizoma atractylodis macrocephalae;
parching radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix for 30min and micronizing for 25min to obtain radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix, respectively;
micronizing xanthan gum, egg essence and calcium citrate, and mixing saccharin sodium and neotame to obtain adjuvants;
mixing the white atractylodes rhizome and the auxiliary materials according to the parts by weight to obtain a first mixture;
mixing the first mixture with radix astragali, semen Coicis, semen lablab album, fructus crataegi, fructus Hordei Germinatus, and radix Glycyrrhizae in the above weight parts to obtain the Chinese medicinal composition.
Mixing the obtained traditional Chinese medicine composition with cold water according to a mass ratio of 1: 6 mixing to obtain the Chinese medicinal paste.
Example 3
The present embodiment provides a traditional Chinese medicine composition for improving intestinal health and a preparation method thereof, which are substantially the same as those in embodiment 1, except that the parameters are different, specifically as follows:
the traditional Chinese medicine composition for improving the intestinal health comprises the following main materials: 32 parts of astragalus membranaceus, 38 parts of bighead atractylodes rhizome, 20 parts of coix seed, 20 parts of white hyacinth bean, 15 parts of hawthorn, 12 parts of malt and 8 parts of liquorice.
In each 100 parts of the main material, the auxiliary material comprises the following components in parts by weight: 0.3 part of xanthan gum, 0.015 part of saccharin sodium, 0.001 part of neotame, 0.2 part of egg essence and 0.8 part of calcium citrate.
The preparation method of the traditional Chinese medicine composition for improving intestinal health provided by the embodiment comprises the following steps:
crushing the rhizoma atractylodis macrocephalae raw materials, and sieving the crushed rhizoma atractylodis macrocephalae raw materials with a 80-mesh sieve to obtain rhizoma atractylodis macrocephalae;
parching radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix for 30min and micronizing for 5min to obtain radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix respectively;
micronizing xanthan gum, egg essence and calcium citrate, and mixing saccharin sodium and neotame to obtain adjuvants;
mixing the white atractylodes rhizome and the auxiliary materials according to the parts by weight to obtain a first mixture;
mixing the first mixture with radix astragali, semen Coicis, semen lablab album, fructus crataegi, fructus Hordei Germinatus, and radix Glycyrrhizae in the above weight parts to obtain the Chinese medicinal composition.
Mixing the obtained traditional Chinese medicine composition with cold water according to a mass ratio of 1: 4, mixing to obtain the Chinese medicinal paste.
Example 4
The present embodiment provides a traditional Chinese medicine composition for improving intestinal health and a preparation method thereof, which are substantially the same as those in embodiment 1, except that the parameters are different, specifically as follows:
the traditional Chinese medicine composition for improving the intestinal health comprises the following main materials: 40 parts of astragalus, 30 parts of bighead atractylodes rhizome, 18 parts of coix seed, 20 parts of white hyacinth bean, 16 parts of hawthorn, 10 parts of malt and 5 parts of liquorice.
In each 100 parts of the main material, the auxiliary material comprises the following components in parts by weight: 0.4 part of xanthan gum, 0.015 part of saccharin sodium, 0.0018 part of neotame, 0.3 part of egg essence and 1.5 parts of calcium citrate.
The preparation method of the traditional Chinese medicine composition for improving intestinal health provided by the embodiment comprises the following steps:
crushing the rhizoma atractylodis macrocephalae raw materials, and sieving the crushed rhizoma atractylodis macrocephalae raw materials by a 120-mesh sieve to obtain rhizoma atractylodis macrocephalae;
parching radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix for 25min and micronizing for 15min to obtain radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix respectively;
micronizing xanthan gum, egg essence and calcium citrate, and mixing saccharin sodium and neotame to obtain adjuvants;
mixing the white atractylodes rhizome and the auxiliary materials according to the parts by weight to obtain a first mixture;
mixing the first mixture with radix astragali, semen Coicis, semen lablab album, fructus crataegi, fructus Hordei Germinatus, and radix Glycyrrhizae in the above weight parts to obtain the Chinese medicinal composition.
Mixing the obtained traditional Chinese medicine composition with cold water according to a mass ratio of 1: 5 mixing to obtain the Chinese medicinal paste.
Verification example 1
The gelatinization degree of the traditional Chinese medicine composition (traditional Chinese medicine paste) prepared by the preparation method provided by the embodiment 1-4 of the invention is verified.
Experimental methods
Cleaning and sorting the traditional Chinese medicinal materials, removing impurities, mildewed and vermigenous medicinal materials, dividing into 6 parts, and preparing the traditional Chinese medicine according to the preparation methods of the embodiments 1-4 and the comparative examples 1-2.
Specifically, the method of comparative example 1 was: the method is approximately the same as the method in the embodiment 1, and is characterized in that the main material and the auxiliary material are directly crushed by a common sieve of 200 meshes (common crushing) without being fried;
the method of comparative example 2 was: the procedure of example 1 was almost the same as that of example 1, except that the main ingredient was directly subjected to ultrafine grinding (micronization) without being parched.
The samples prepared in comparative examples 1 to 2 and examples 1 to 4 were tested for their gelatinization degree by the method of "starch gelatinization degree determination-potassium ferricyanide method", and the results are shown in table 1.
Results of the experiment
TABLE 1 degrees of gelatinization of the different preparation processes
| Sample (I) | Comparative example 1 | Comparative example 2 | Example 1 | Example 2 | Example 3 | Example 4 |
| Degree of gelatinization (%) | 26.17 | 58.63 | 75.31 | 79.83 | 72.35 | 74.19 |
As is clear from table 1, the preparation methods provided in examples 1 to 4 of the present invention significantly improved the degree of gelatinization of the Chinese medicinal paste, compared to comparative examples 1 to 2.
Verification example 2
The influence of the traditional Chinese medicine composition prepared by the preparation method provided in the embodiment 1-4 on the production performance of weaned piglets is verified.
Test field: a pig farm in the west of the river. Test time: 35 days from 3 months 1 day in 2019 to 4 months 5 days in 2019. Test animals: 240 healthy Du/long/big ternary hybrid pigs aged 26-28 days and having a weight of 7.72kg +/-0.68 kg are selected.
The test materials are as follows: the method for preparing the traditional Chinese medicine pastes (test groups 1-4) prepared by the preparation methods of the above embodiments 1-4 is that 3 control groups are set in comparison, and the method for the comparison is as follows:
the method for control 1 was: compared with the embodiment 1, the difference lies in that the main material is directly crushed into superfine powder without being fried;
the method for control group 2 was: compared with the embodiment 1, the difference is that the astragalus root in the main material is replaced by the atractylodes macrocephala koidz with the same amount;
the method for the control group 3 was: compared with the embodiment 1, the difference is that the hawthorn in the main material is replaced by the malt with the same amount.
240 weaned piglets are randomly divided into 8 groups, the traditional Chinese medicine pastes prepared by the preparation methods provided by the test groups 1-4 and the control groups 1-3 are respectively adopted for feeding, a blank group (electrolysis multi-dimensional) is further arranged, each treatment group has 3 repetitions, and each repetition has 10 pigs. Feeding by special people, feeding 4 g/head of Chinese medicinal paste before feeding every morning and evening, drinking electrolytic multivitamin for blank group, and freely feeding and drinking water for other feeding management under the same environmental conditions. Daily feedings and diarrhea pigs were recorded.
The test pigs were weighed on an empty stomach at 8:00 am and 18:00 pm on the day of the beginning and end of the test, the feed intake and diarrhea rate 3 days before the test were recorded, and the daily gain, daily feed intake and feed conversion ratio of each group were counted after the end of the positive test period. The test results are shown in Table 2.
Test results
TABLE 2 Effect of different Chinese medicinal cataplasms on growth Performance of weaned piglets
As can be seen from Table 2, the average total feed intake of piglets in the test group 1-4 in the first 3 days after weaning is 523g, which is 51.16% higher than that of the blank group, the difference is very obvious (P is less than 0.01), and the difference is very obvious (P is less than 0.01) and 23.64% higher than that of the control group 1; the improvement is 18.59 percent compared with the control group 2, and the difference is very obvious (P is less than 0.01); the contrast is improved by 15.71 percent compared with the contrast group 3, and the difference is very obvious (P is less than 0.01); the test group 4 shows that the total feed intake of the piglets in 3 days before weaning is 541g, and the optimal result shows that the traditional Chinese medicine composition provided by the invention can obviously improve the total feed intake of the piglets in 3 days before weaning.
The average daily gain of piglets in the test group 1-4 is 361.35g, which is improved by 24.97 percent compared with the blank group, the difference is very obvious (P is less than 0.01), and is improved by 18.53 percent compared with the control group 1, and the difference is very obvious (P is less than 0.01); the improvement is 13.23 percent compared with the control group 2, and the difference is very obvious (P is less than 0.01); the improvement is 11.14 percent compared with the control group 3, and the difference is obvious (P is less than 0.05); wherein, the daily gain of the piglets in the test group 4 reaches 374.82g, which is the optimal result. Therefore, the traditional Chinese medicine composition provided by the embodiment of the invention can be used for remarkably improving the growth of piglets.
The average daily feed intake of piglets in the test groups 1-4 is 564.30g, which is 12.81% higher than that of the blank group, the difference is very obvious (P is less than 0.01), and the difference is very obvious (P is less than 0.01) and is 10.84% higher than that of the control group 1; the improvement is 7.16 percent compared with the control group 2, and the difference is obvious (P is less than 0.05); the yield is improved by 6.48 percent compared with that of a control group 3, and the difference is obvious (P is less than 0.05); the piglet feed intake of the test group 1 and the piglet feed intake of the test group 4 respectively reach 571.28g and 573.48g, and therefore the traditional Chinese medicine composition provided by the embodiment of the invention can improve the piglet feed intake.
The average feed-meat ratio of piglets in the test groups 1-4 is 1.56, which is reduced by 0.17 compared with that in the blank group and is obviously lower than that in the control groups 1-3; the feed-meat ratio of the test group 4 is 1.53, and the optimal result is obtained. The traditional Chinese medicine composition provided by the invention can effectively improve the utilization rate of feed.
The average diarrhea rate of piglets in the test groups 1-4 is 4.78%, the average diarrhea rate is reduced by 26.80% compared with that of the piglets in the blank group, the difference is extremely obvious (P is less than 0.01), the average diarrhea rate is improved by 20.60% compared with that of the piglets in the control group 1, and the difference is extremely obvious (P is less than 0.01); the improvement is 17.30 percent compared with the control group 2, and the difference is very obvious (P is less than 0.01); compared with the control group 3, the improvement is 12.45 percent, and the difference is very obvious (P is less than 0.01).
The test results show that the traditional Chinese medicine paste provided by the embodiment of the invention can obviously reduce weaning stress and diarrhea rate, obviously reduce feed conversion ratio and improve the feed intake of piglets after weaning. The test groups 1-4 are compared with the control group 1, and the result shows that the fried and then superfine-pulverized traditional Chinese medicine paste has better effect, higher gelatinization degree, easier digestion and better taste than the directly superfine-pulverized traditional Chinese medicine paste; the results of the comparison between the test groups 1-4 and the control groups 2 and 3 show that the test effect of the control group 2 (the traditional Chinese medicine paste lacking astragalus root) or the control group 3 (the traditional Chinese medicine paste lacking hawthorn fruit) is inferior to that of the test groups 1-4 (the traditional Chinese medicine paste lacking hawthorn fruit), which indicates that the synergistic effect exists among the compatible components.
In summary, the embodiment of the present invention provides a traditional Chinese medicine composition for improving intestinal health, which comprises 20-45 parts of astragalus membranaceus, 18-40 parts of bighead atractylodes rhizome, 13-28 parts of coix seed, 10-30 parts of white hyacinth bean, 10-22 parts of hawthorn, 8-20 parts of malt and 3-10 parts of licorice. The traditional Chinese medicine composition takes astragalus and bighead atractylodes rhizome as monarch drugs according to the compatibility principle of traditional Chinese medicines, and the astragalus and the bighead atractylodes rhizome have the effects of tonifying qi, invigorating spleen and excreting dampness; the coix seed and the malt are used as ministers to help strengthen the spleen and stomach; fructus crataegi and fructus Hordei Germinatus as adjuvant drugs for invigorating spleen and eliminating dampness; the composition prepared from the components of the liquorice, the qi tonifying, the middle warmer regulating and the other medicines harmonizing has the effects of improving the problem of gastrointestinal tract function decline of weaned pigs, reducing the adverse effect of weaning stress on intestinal villus structures of the piglets, reducing the diarrhea rate and further improving the culture benefit.
The embodiment of the invention also provides a preparation method of the traditional Chinese medicine composition, and the preparation method comprises the step of mixing the traditional Chinese medicine composition. The preparation method is simple and easy to implement, the production process flow is short, the product is convenient to use, the paste can be prepared by directly using a proper amount of cold water, and the intestinal health problem can be effectively improved without a specific feeding system and equipment.
In addition, the embodiment of the invention provides the application of the traditional Chinese medicine composition for improving the intestinal health or the traditional Chinese medicine composition for improving the intestinal health prepared by the preparation method in weaned pigs.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. The traditional Chinese medicine composition for improving the intestinal health is characterized by comprising main materials, wherein the main materials comprise the following components in parts by weight: 20-45 parts of astragalus membranaceus, 18-40 parts of bighead atractylodes rhizome, 13-28 parts of coix seed, 10-30 parts of white hyacinth bean, 10-22 parts of hawthorn, 8-20 parts of malt and 3-10 parts of liquorice;
preferably, the traditional Chinese medicine composition further comprises an auxiliary material, and the auxiliary material comprises at least one of a thickening agent, a sweetening agent, a flavoring agent and an acidifying agent.
2. The traditional Chinese medicine composition for improving the intestinal health according to claim 1, wherein the main material comprises the following components in parts by weight: 38-42 parts of astragalus membranaceus, 28-38 parts of bighead atractylodes rhizome, 16-22 parts of coix seed, 13-22 parts of white hyacinth bean, 12-17 parts of hawthorn, 8-12 parts of malt and 4-6 parts of liquorice;
preferably, the adjunct comprises at least one of a thickener, a sweetener, a flavoring agent, and an acidulant;
preferably, in each 100 parts of the main material, the auxiliary materials comprise the following components in parts by weight: 0.2-1.0 part of thickening agent, 0.01-0.02 part of sweetening agent, 0.1-0.5 part of flavoring agent and 0.5-2.5 parts of acidifying agent;
preferably, the thickener is selected from one or more of hydroxypropyl methylcellulose, xanthan gum and polyvinylpyrrolidone, preferably xanthan gum;
preferably, the sweetener comprises sodium saccharin and neotame;
preferably, the flavoring agent comprises egg essence;
preferably, the acidulant is selected from at least one of calcium citrate, calcium fumarate and calcium acetate, preferably calcium citrate.
3. The traditional Chinese medicine composition for improving the intestinal health of claim 1, wherein the traditional Chinese medicine composition is a traditional Chinese medicine paste;
preferably, the traditional Chinese medicine composition further comprises water, and the mass ratio of the main material to the water is 1: (4-6).
4. The traditional Chinese medicine composition for improving the intestinal health as claimed in claim 1, wherein the white atractylodes rhizome is obtained by crushing; more preferably, the particle size of the bighead atractylodes rhizome is 80-200 meshes.
5. The traditional Chinese medicine composition for improving the intestinal health as claimed in claim 1, wherein the main materials except for the white atractylodes rhizome are obtained by stir-frying and superfine grinding;
preferably, the auxiliary material is obtained by micronizing at least one of a thickener, a flavoring agent and an acidulant.
6. The method for preparing a traditional Chinese medicine composition for improving the intestinal health according to any one of claims 1 to 5, which comprises mixing the raw materials of the traditional Chinese medicine composition;
preferably, the method comprises:
pulverizing rhizoma Atractylodis Macrocephalae, and sieving to obtain rhizoma Atractylodis Macrocephalae;
micronizing one or more of thickener, sweetener, flavoring agent and acidifier to obtain adjuvant;
parching and micronizing radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix to obtain radix astragali, Coicis semen, semen lablab album, fructus crataegi, fructus Hordei Germinatus and Glycyrrhrizae radix respectively;
mixing the white atractylodes rhizome and auxiliary materials according to the parts by weight to obtain a first mixture;
mixing the first mixture with radix astragali, semen Coicis, semen lablab album, fructus crataegi, fructus Hordei Germinatus, and radix Glycyrrhizae according to weight parts to obtain the Chinese medicinal composition.
7. The preparation method of the traditional Chinese medicine composition for improving the intestinal health, according to claim 6, is characterized in that the sieving is carried out by sieving with a sieve of 80-200 meshes.
8. The method for preparing a traditional Chinese medicine composition for improving intestinal health according to claim 7, wherein the stir-frying time for the superfine grinding after stir-frying is 15-30 min, and the superfine grinding time for the superfine grinding after stir-frying is 5-30 min.
9. The traditional Chinese medicine composition for improving the intestinal health as claimed in any one of claims 1 to 5 or the traditional Chinese medicine composition for improving the intestinal health as claimed in any one of claims 6 to 8, and the application of the prepared traditional Chinese medicine composition in weaned piglets.
10. The use of the Chinese medicinal composition of claim 9 in weaned piglets, wherein the amount of the Chinese medicinal composition is 3-9 g/head per day.
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