CN110585411A - 温中止喘口服液 - Google Patents

温中止喘口服液 Download PDF

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Publication number
CN110585411A
CN110585411A CN201910921417.4A CN201910921417A CN110585411A CN 110585411 A CN110585411 A CN 110585411A CN 201910921417 A CN201910921417 A CN 201910921417A CN 110585411 A CN110585411 A CN 110585411A
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China
Prior art keywords
component
mixing
oral liquid
prepared
warming middle
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CN201910921417.4A
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Inventor
赵升瑞
赵景颢
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Individual
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Priority to CN201910921417.4A priority Critical patent/CN110585411A/zh
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    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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Abstract

本发明公开了一种温中止喘口服液，由增加元气，提高免疫力，转化过敏体质的组份A、宣肺散寒的组份B、宣肺去热的组份C、止咳平喘的组份D以及祛湿化痰的组份E按重量比混合制成，本发明通过不同的重量比的口服液增加了人体内的元气，提高了人体的免疫力，降低肺与呼吸道对外界的敏感性，抑制平滑肌的收缩，同时可以清火、润燥、平喘、止咳化痰，且可以清除体内的虚寒之气，达到治愈各类型哮喘的目的，疗程短且疗效好。

Description

温中止喘口服液
技术领域
本发明属于中药技术领域，具体涉及一种温中止喘口服液。
背景技术
哮喘又名支气管哮喘，是一种具有复杂性状的、多基因遗传倾向的疾病，主要症状有：喘息、气促、胸闷、咳嗽、痰多等症状，有广泛而多变的气流阻塞，并发症有慢性鼻炎、慢性支气管炎、和肺慢阻，严重的导致肺活量下降，肺功能衰竭，更为严重的会危及生命，且多在夜间和凌晨发生和加重；西医认为，哮喘是由于各种过敏源进入体内，诱发体内发生变态反应，从而产生大量的组织胺，组织胺会刺激支气管平滑机收缩，支气管狭窄，并诱发黏膜产生大量的粘液和淋巴细胞浸润，引起支气管道慢性炎症和气道高反应性，气道阻塞性反应，从而诱发了哮喘的各种症状的发生，西医认为哮喘激发的因素有：各种变应原(吸入、食物、食物添加剂、药物等)、温度差、过度疲劳、精神因素(紧张、悲伤、高兴)、呼吸道病毒感染、吸烟以及大气污染等；而中医认为哮喘病多由外邪侵袭、饮食不当、情志失调、久病劳欲引起，风寒或风热袭肺，未能及时表散而蕴于肺，壅阻肺气，致使肺气失于宣降而上逆作喘；恣食肥甘、生冷，或嗜酒伤中，脾失健运，痰浊内生，壅阻肺气，肃降失常而发为喘促；情志不遂，忧思气结，则气阻胸中，或郁怒伤肝，肝木反侮肺金，使肺气不得肃降，以致肺气上逆而哮喘；久咳伤肺或久病脾虚使肺失充养，导致肺之气阴不足，气失所主而作哮喘，中医根据发病情况，将哮喘分为三种类型：寒型哮喘、热型哮喘以及虚型哮喘，哮喘病的病变部位主要在肺和肾，与肝、脾、心有关，病理性质有虚实之分，但在病情发展的不同阶段，虚实之间可互相转化，出现虚实夹杂之错综局面；一般实喘在肺，虚喘责之于肺、肾，哮喘病的严重阶段，不但肺肾俱虚，在孤阳欲脱之时，可病及于心，甚则喘汗致脱。
目前，治疗哮喘的西药很多，治疗方法也很多，对解决重症患者和急症患者都有非常显著的疗效，这是目前中药所不能达到的，但是西药治疗过敏性哮喘也有很多缺点，其副作用大，用药后症状消失，药停还会复发，反复使用，病人会产生一定的耐药性和抗药性，导致药物效果越来越差，尤其是激素类药物，虽然见效很快，但会使病人的身体发胖，身体更虚弱，后面发作会更严重；中医治疗哮喘的方剂和方法也非常的多，还包括一些偏方，对哮喘的治疗都有十分显著的作用，这些方剂都注重了患者的个体性差异，如果是经验十分丰富的老中医，选对方剂也可以治愈哮喘；但是对绝大部分的现代中医大夫来说，由于中医基础理论知识和临床经验所限，在如此豪瀚的配方中去选用适合的方剂，非常困难，所以绝大多数人治疗效果不是很理想。
发明内容
为了解决现有技术中存在的上述问题，本发明提供了一种温中止喘口服液，纯中药制剂，无药品依赖性，治疗程序简单、疗程短、疗效快、无毒副作用。
本人借鉴中西治疗的宝贵经验，总结现存中西医治疗哮喘存在的问题，以中医系统治疗理论、生物学理论和现代医学理论为指导思想，以中医方剂为治疗手段，既强调了中医治疗的个体差异性，更突出了普遍性，认为应该从以下方面治疗哮喘：
1、通过补肾养肺增加身体元气，提高自身的免疫力，转化过敏体质，提高对外界风、寒、湿、热的抵抗力，使身体不再发生变态反应，体内不再产生组织胺，抑制平滑肌的收缩，消除喘息症状。
2、宣肺散寒。
3、宣肺去热。
4、止咳。
5、化痰。
据此，研制出了纯中药的温中止喘口服液，所述温中止喘口服液由下述重量比的组分混合后加4％-6％的粮食白酒密封保存3-6个月后制成：组份A：2-8；组份B：1-8；组份C：1-8；组份D：2-3；组份E：2-3；
所述组份A由党参55-65g、生地55-65g、枸杞子55-65g、当归55-65g、紫河车一具、黄芪55-65g、葛根28-32g、丹参37-43g、阿胶28-32g、生山楂28-32g、桑寄生28-32g制成；制备方法：将所述党参、所述生地、所述枸杞子、所述当归、所述紫河车、所述黄芪、所述葛根、所述丹参、所述阿胶、所述生山楂、所述桑寄生混合后研磨至60目-80目的颗粒，水煎20-25min，取煎剂和药渣混合共用得到所述组份A；
所述组份B由去节麻黄5-7g、去皮尖杏仁5-7g、炒甘草5-7g、桂枝8-10g、茯苓8-10g、丹皮8-10g、芍药8-10g、桃仁8-10g、细辛2-4g、干姜8-12g、五味子5-7g、半夏8-12g制成；制备方法：将所述去节麻黄、所述去皮尖杏仁、所述炒甘草、所述桂枝、所述茯苓、所述丹皮、所述芍药、所述桃仁、所述细辛、所述干姜、所述五味子、所述半夏混合后，水煎20-25min，取煎剂得到所述组份B；
所述组份C由连翘7-9g、薄荷3-5g、桑叶10-14g、桂枝5-7g、菊花4-6g、苦梗8-12g，苇根8-12g、地骨皮25-35g、炒桑白皮25-35g、炙甘草2-4g、木防己8-10g、石膏25-35g制成；制备方法：将所述连翘、所述薄荷、所述桑叶、所述桂枝、所述菊花、所述苦梗、所述苇根、所述地骨皮、所述炒桑白皮、所述炙甘草、所述木防己、所述石膏混合后，水煎20-25min，取煎剂得到所述组份C；
所述组份D由知母55-65g、贝母55-65g、百药煎25-35g制成；制备方法：将所述知母、所述贝母、所述百药煎混合后研磨至60目-80目的颗粒，水煎20-25min，取煎剂和药渣混合共用得到所述组份D；
所述组份E由鲜竹沥80-100g、薄橘红1-2g、天花粉8-10g、生薏仁8-10g、全瓜蒌10-14g、象贝母8-10g、苦杏仁8-10g、嫩前胡2-4g、薄荷叶2-4g、牛蒡子4-5g、降香1-3g、川郁金5-7g制成；制备方法：将所述鲜竹沥、所述薄橘红、所述天花粉、所述生薏仁、所述全瓜蒌、所述象贝母、所述苦杏仁、所述嫩前胡、所述薄荷叶、所述生蒡子、所述降香、所述川郁金混合后，水煎20-25min，取煎剂得到所述组份E。
优选地，所述温中止喘口服液由下述重量比的组份混合后加4％-6％的粮食白酒密封保存3-6个月后制成：A:B:C:D:E＝2:1:8:3:3。
优选地，所述温中止喘口服液由下述重量比的组份混合后加4％-6％的粮食白酒密封保存3-6个月后制成：A:B:C:D:E＝4:8:1:2:2。
优选地，所述温中止喘口服液由下述重量比的组份混合后加4％-6％的粮食白酒密封保存3-6个月后制成：A:B:C:D:E＝8:2:1:3:3。
本发明的有益效果：
1、通过增加人体内的元气，提高人体的免疫力，且能转化过敏体质，遇到过敏原后不会再过敏；
2、通过降低肺与呼吸道对外界的敏感性，抑制平滑肌的收缩；
3、可以清火、润燥、平喘、止咳化痰，且可以清除体内的虚寒之气，达到治愈各种类型哮喘的目的；
4、本发明属于纯中药制剂、无药品依赖性、无毒副作用、疗程短、疗效好。
具体实施方式
下面结合具体实施例对本发明做进一步详细的描述，但本发明的实施方式不限于此。
实施例1
本发明实施例提供了一种温中止喘口服液，该温中止喘口服液由下述组分混合后加5％的60°以上的粮食白酒密封保存3-6个月后制成。
组份A由党参60g、生地60g、枸杞子60g、当归60g、紫河车一具、黄芪60g、葛根30g、丹参40g、阿胶30g、生山楂30g、桑寄生30g制成；制备方法：将党参、生地、枸杞子、当归、紫河车、黄芪、葛根、丹参、阿胶、生山楂、桑寄生混合后研磨至80目的颗粒，水煎20-25min，取煎剂和药渣混合共用得到组份A，组份A用于增加元气，提高免疫力，转化过敏体质。
组份B由去节麻黄6g、去皮尖杏仁6g、炒甘草6g、桂枝9g、茯苓9g、丹皮9g、芍药9g、桃仁9g、细辛3g、干姜10g、五味子6g、半夏10g制成；制备方法：将去节麻黄、去皮尖杏仁、炒甘草、桂枝、茯苓、丹皮、芍药、桃仁、细辛、干姜、五味子、半夏混合后，水煎20-25min，取煎剂得到组份B，组份B用于宣肺散寒。
组份C由连翘8g、薄荷4g、桑叶12g、桂枝6g、菊花5g、苦梗10g，苇根10g、地骨皮30g、炒桑白皮30g、炙甘草3g、木防己9g、石膏30g制成；制备方法：将连翘、薄荷、桑叶、桂枝、菊花、苦梗、苇根、地骨皮、炒桑白皮、炙甘草、木防己、石膏混合后，水煎20-25min，取煎剂得到组份C，组份C用于宣肺去热。
组份D由知母60g、贝母60g、百药煎30g制成；制备方法：将知母、贝母、百药煎混合后研磨至80目的颗粒，水煎20-25min，取煎剂和药渣混合共用得到组份D，组份D用于止咳。
组份E由鲜竹沥90g、薄橘红1.5g、天花粉9g、生薏仁9g、全瓜蒌12g、象贝母9g、苦杏仁9g、嫩前胡3g、薄荷叶3g、牛蒡子4.5g、降香2g、川郁金6g制成；制备方法：将鲜竹沥、薄橘红、天花粉、生薏仁、全瓜蒌、象贝母、苦杏仁、嫩前胡、薄荷叶、生蒡子、降香、川郁金混合后，水煎20-25min，取煎剂得到组份E，组份E用于祛湿化痰。
针对热型哮喘，温中止喘口服液由下述重量比的组份混合后加5％的60°以上的粮食白酒密封保存3-6个月后制成：
A:B:C:D:E＝2:1:8:3:3。
针对寒型哮喘，温中止喘口服液由下述重量比的组份混合后加5％的60°以上的粮食白酒密封保存3-6个月后制成：
A:B:C:D:E＝4:8:1:2:2。
针对虚型哮喘，温中止喘口服液由下述重量比的组份混合后加5％的60°以上的粮食白酒密封保存3-6个月后制成：
A:B:C:D:E＝8:2:1:3:3。
需要说明的是，加入粮食白酒是起防腐保鲜作用，5％的粮食白酒是相对于最后得到的药剂的容积来说的，例如，最后得到100mL的药剂，需添加5mL的粮食白酒用于防腐保鲜。
本发明组方依据中医注重阴阳平衡的治疗原则，在治疗热型哮喘的组方中，添加组份A用于增加元气，添加组份B用于宣肺散寒，防止在治疗过程中导致患者体虚、体寒；在治疗寒型哮喘的组方中，添加组份A用于增加元气，添加组份C用于宣肺去热，防止在治疗过程中导致患者体虚、体热；在治疗虚型哮喘的组方中，添加组份B用于宣肺散寒，添加组份C用于宣肺去热。
本发明治疗范围：热型哮喘、寒型哮喘、虚型哮喘。
本发明的用法用量：
1、体质强健的成年男性患者：50-100mL/日，上午15-30mL口服液，加500-600mL水，可以加入蜂蜜调味至口感适宜，边喝边加水；下午15-30mL，晚上20-40mL，喝法均同上午，一个疗程两个月。
2、体质虚弱的男性患者和体质健康的成年女性患者：30-50mL/日，上午10-15mL口服液，加500-600mL水，可以加入蜂蜜调味至口感适宜，边喝边加水；下午10-15mL，晚上10-20mL，喝法均同上午，一个疗程两个月。
3、青少年患者和体质虚弱的女性患者：10-30mL/日，上午3-10mL口服液，加500-600mL水，可以加入蜂蜜调味至口感适宜，边喝边加水；下午3-10mL，晚上4-10mL，喝法均同上午，一个疗程两个月。
4、幼儿患者：5-15mL/日，上午1.5-5mL口服液，加200mL水，可以加入蜂蜜调味至口感适宜，边喝边加水；中午1.5-5mL，晚上2-5mL，喝法均同上午，一个疗程两个月。
需要说明的是，对蜂蜜过敏的患者在内服本药物时切勿添加蜂蜜。
需要说明的是，本发明口服液服用时加水的目的是为了降低口服液中酒精的浓度，以免个别患者酒精过敏，使其便于服用，由于本发明口服液的浓度很高，加水并不会影响药物的疗效。
本发明经宝鸡市渭滨区中滩路社区卫生站、宝鸡市渭滨区英达路康达诊所临床观察，结果如下：
患者服用本发明的温中止喘口服液后，治愈后不再发作，本发明的温中止喘口服液临床应用已达六年，治愈的患者都未再复发。
本发明通过增加元气、宣肺散寒、宣肺去热、止咳平喘、祛湿化痰，达到治愈哮喘的目的，治愈率达到100％。
以上内容是结合具体的优选实施方式对本发明所作的进一步详细说明，不能认定本发明的具体实施只局限于这些说明。对于本发明所属技术领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干简单推演或替换，都应当视为属于本发明的保护范围。

Claims (4)

1.一种温中止喘口服液，其特征在于，
所述温中止喘口服液由下述重量比的组分混合后加4％-6％的粮食白酒密封保存3-6个月后制成：组份A：2-8；组份B：1-8；组份C：1-8；组份D：2-3；组份E：2-3；
所述组份A由党参55-65g、生地55-65g、枸杞子55-65g、当归55-65g、紫河车一具、黄芪55-65g、葛根28-32g、丹参37-43g、阿胶28-32g、生山楂28-32g、桑寄生28-32g制成；制备方法：将所述党参、所述生地、所述枸杞子、所述当归、所述紫河车、所述黄芪、所述葛根、所述丹参、所述阿胶、所述生山楂、所述桑寄生混合后研磨至60目-80目的颗粒，水煎20-25min，取煎剂和药渣混合共用得到所述组份A；
所述组份B由去节麻黄5-7g、去皮尖杏仁5-7g、炒甘草5-7g、桂枝8-10g、茯苓8-10g、丹皮8-10g、芍药8-10g、桃仁8-10g、细辛2-4g、干姜8-12g、五味子5-7g、半夏8-12g制成；制备方法：将所述去节麻黄、所述去皮尖杏仁、所述炒甘草、所述桂枝、所述茯苓、所述丹皮、所述芍药、所述桃仁、所述细辛、所述干姜、所述五味子、所述半夏混合后，水煎20-25min，取煎剂得到所述组份B；
所述组份C由连翘7-9g、薄荷3-5g、桑叶10-14g、桂枝5-7g、菊花4-6g、苦梗8-12g，苇根8-12g、地骨皮25-35g、炒桑白皮25-35g、炙甘草2-4g、木防己8-10g、石膏25-35g制成；制备方法：将所述连翘、所述薄荷、所述桑叶、所述桂枝、所述菊花、所述苦梗、所述苇根、所述地骨皮、所述炒桑白皮、所述炙甘草、所述木防己、所述石膏混合后，水煎20-25min，取煎剂得到所述组份C；
所述组份D由知母55-65g、贝母55-65g、百药煎25-35g制成；制备方法：将所述知母、所述贝母、所述百药煎混合后研磨至60目-80目的颗粒，水煎20-25min，取煎剂和药渣混合共用得到所述组份D；
所述组份E由鲜竹沥80-100g、薄橘红1-2g、天花粉8-10g、生薏仁8-10g、全瓜蒌10-14g、象贝母8-10g、苦杏仁8-10g、嫩前胡2-4g、薄荷叶2-4g、牛蒡子4-5g、降香1-3g、川郁金5-7g制成；制备方法：将所述鲜竹沥、所述薄橘红、所述天花粉、所述生薏仁、所述全瓜蒌、所述象贝母、所述苦杏仁、所述嫩前胡、所述薄荷叶、所述生蒡子、所述降香、所述川郁金混合后，水煎20-25min，取煎剂得到所述组份E。
2.根据权利要求1所述的温中止喘口服液，其特征在于，所述温中止喘口服液由下述重量比的组份混合后加4％-6％的粮食白酒密封保存3-6个月后制成：A:B:C:D:E＝2:1:8:3:3。
3.根据权利要求1所述的温中止喘口服液，其特征在于，所述温中止喘口服液由下述重量比的组份混合后加4％-6％的粮食白酒密封保存3-6个月后制成：A:B:C:D:E＝4:8:1:2:2。
4.根据权利要求1所述的温中止喘口服液，其特征在于，所述温中止喘口服液由下述重量比的组份混合后加4％-6％的粮食白酒密封保存3-6个月后制成：A:B:C:D:E＝8:2:1:3:3。
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