CN110585337A - Traditional Chinese medicine formula for tonifying qi and blood and preparation method thereof - Google Patents

Traditional Chinese medicine formula for tonifying qi and blood and preparation method thereof Download PDF

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CN110585337A
CN110585337A CN201910991006.2A CN201910991006A CN110585337A CN 110585337 A CN110585337 A CN 110585337A CN 201910991006 A CN201910991006 A CN 201910991006A CN 110585337 A CN110585337 A CN 110585337A
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孙朋付
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
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Abstract

A traditional Chinese medicine formula for tonifying qi and blood and a preparation method thereof are disclosed, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: 2-6 parts of polygonatum odoratum, 2-6 parts of mulberry, 2-6 parts of poria cocos, 2-6 parts of sea buckthorn, 2-6 parts of rhizoma polygonati, 1-5 parts of angelica sinensis, 1-5 parts of raspberry, 1-4 parts of towel gourd, 1-4 parts of onion and 1-2 parts of ginseng. Decocting in water, filtering, concentrating to obtain extract, and making into granule. Has good conditioning and treating effects on various deficiency of qi and blood, weakness of spleen and stomach, hypotension anemia. Has good effects of recovering and conditioning the body after postpartum operation and replenishing qi and blood.

Description

Traditional Chinese medicine formula for tonifying qi and blood and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine formula for tonifying qi and blood, is suitable for traditional Chinese medicine formula combination for qi and blood deficiency, weak constitution and postpartum postoperative recovery, and belongs to the field of traditional Chinese medicine treatment.
Background
Deficiency of qi and blood is very common among people, and generally manifested as dizziness, weakness, fatigue, shortness of breath, no speaking desire, pale or sallow complexion, palpitation, insomnia, dreaminess, pale and tender tongue, thready and weak pulse, etc., especially for women, deficiency of qi and blood is very common due to congenital physiological reasons, and in addition, after delivery, operation and illness, qi and blood are lost to aggravate symptoms. Deficiency of qi and blood is clinically equivalent to hypotension, anemia or sub-health in western medicine. More times, as various clinical indexes are close to normal, the patients are often misdiagnosed as neurosis, neurasthenia, insufficient blood supply to heart and brain, and the like. The influence of deficiency of qi and blood on human is all-round in many aspects, blood supply insufficiency can occur to all limbs and bodies of all organs of the whole body, especially cerebral blood supply insufficiency is caused, heart blood supply insufficiency seriously influences the life quality of patients, even syncope and falling injury can be caused, various diseases can be induced, and serious consequences can be caused. Because the disease is hidden and the clinical manifestations are various, the misdiagnosis rate is very high, and because doctors and patients generally do not pay enough attention to the disease, and at present, safe, effective, reasonable and formal medicines and methods are newly sold on the market, so that vast patients cannot be diagnosed and treated correctly and reasonably.
At present, the traditional Chinese medicines for treating deficiency of qi and blood are mainly prepared by mutually matching and cutting qi-tonifying medicines such as ginseng, codonopsis pilosula, astragalus and the like and blood-tonifying medicines such as angelica, Chinese date, donkey-hide gelatin and the like, such as a Shiquandabu pill, a Sijunzi decoction, a Guipi decoction and the like which are widely applied clinically.
Because ginseng is classified as the main formula, when eaten, the warm and dry food is easy to cause excessive internal heat, dry throat and sore throat, while patients with deficiency of qi and blood are easy to cause deficient fire, and the consumption of the food is easy to help deficient fire to be exuberant; however, the sticky and sticky food of donkey-hide gelatin can easily damage the spleen and stomach, most of patients with deficiency of qi and blood are weak in the spleen and stomach, and when the donkey-hide gelatin is eaten, the donkey-hide gelatin is not reactive but harmful. Some Chinese medicine experts and scholars can ask the phoenix feather unicorn at present by disputing and treating the prescription to take medicine, can accurately cope with the physical and the state of illness of patients and avoid the side effect of the medicine, but doctors in the same country can call the phoenix feather unicorn at present, which influences the popularization and limits the application to a great extent. In addition, some commonly used clinical products such as pilose antler, human placenta (including animal placenta) and the like have poor and satisfactory practical application effects, and the sanitary conditions of smelly materials and filthy substances like donkey-hide gelatin are great and worried, so that people can avoid three hurdles. Therefore, every time a patient suffers from deficiency of qi and blood, the patient always has to take chess to go about losing the chess, and it is difficult to find a proper product for use. In the practical clinical work, a product which is simple, convenient, healthy, sanitary, safe, nontoxic and good in effect is urgently needed.
The invention aims to provide a simple, convenient, healthy and sanitary product which is safe, non-toxic and excellent in effect aiming at the above situation, and a traditional Chinese medicine formula for tonifying qi and blood and a preparation method thereof, wherein the traditional Chinese medicine formula is used for treating deficiency of qi and blood, weakness of spleen and stomach and poor constitution and immunity.
The invention is realized by the following technical scheme: the composition comprises the following raw material medicines in parts by weight: 2-6 parts of polygonatum odoratum, 2-6 parts of mulberry, 2-6 parts of poria cocos, 2-6 parts of sea buckthorn, 2-6 parts of rhizoma polygonati, 1-5 parts of angelica sinensis, 1-5 parts of raspberry, 1-4 parts of towel gourd, 1-4 parts of onion and 1-2 parts of ginseng.
The preferred traditional Chinese medicine composition comprises the following raw material medicines in parts by weight: 3 parts of polygonatum, 3 parts of mulberry, 3 parts of poria cocos, 3 parts of sea-buckthorn, 3 parts of rhizoma polygonati, 2 parts of angelica sinensis, 2 parts of raspberry, 3 parts of towel gourd, 3 parts of onion and 1 part of ginseng.
The preparation method adopting the composition comprises the following steps: weighing 2-6 parts of polygonatum odoratum, 2-6 parts of mulberry, 2-6 parts of poria cocos, 2-6 parts of sea buckthorn, 2-6 parts of rhizoma polygonati, 1-5 parts of angelica sinensis, 1-5 parts of raspberry, 1-4 parts of towel gourd, 1-4 parts of onion and 1-2 parts of ginseng. Selecting, cleaning and mixing uniformly, adding water with 2 times of the total amount of the raw materials, decocting for 1-2 hours at 100-120 ℃, collecting filtrate, filtering out medicine residues, adding proper amount of water, boiling with strong fire, adding water for decocting twice, filtering, and combining decoctions obtained in the two times. Concentrating the extract at 100-140 ℃, further drying the extract, preparing the extract into 10-12 mesh granules by a granulator, drying the granules at 50-60 ℃, and sieving and granulating the granules to obtain the granules. If the production capacity is large, the two decoctions can be spray-dried and granulated by special machine to obtain granules.
The Chinese medicinal composition can also be prepared into pills, tablets, capsules and syrup.
The applicant of the invention has abundant experience in the study of the qi-blood health-preserving traditional Chinese medicine formula for more than twenty years in clinical medicine work, and practice proves that the formula of the invention has good conditioning and treating effects on treating various qi-blood deficiency caused by qi-blood deficiency, spleen-stomach weakness and hypotension anemia. Has good effects of recovering and conditioning the body after postpartum operation and replenishing qi and blood.
The invention has the following advantages: the traditional old qi and blood tonifying method taking ginseng, donkey-hide gelatin and angelica as main medicines is abandoned, the sealwort qi tonifying and yin nourishing, spleen strengthening and kidney tonifying, polygonatum odoratum tonifying, spleen strengthening, yin nourishing and body fluid production are innovatively adopted, the two medicines are used together for tonifying spleen and kidney, spleen strengthening and yin nourishing are the acquired root, poria cocos permeates dampness, invigorates spleen and stomach, digestion and absorption of spleen and stomach are promoted together, qi and blood generation by food essence is facilitated, qi and blood generation is enabled to be active, and sealwort and polygonatum odoratum yin nourishing and body fluid production are used for supplementing visible blood as the mona; the ministerial drugs mulberry tonify liver and kidney, raspberry tonifies kidney and fixes essence, kidney stores essence, kidney essence generates marrow, and marrow can generate blood, and meanwhile, kidney essence and liver blood mutually nourish essence and generate sufficient blood; ginseng and Chinese angelica, which are common products for tonifying qi and generating blood, are warm and dry in nature and easy to generate dry fire, and are used together as adjuvant drugs in a formula with a proper amount of polygonatum and polygonatum nourishing products, so that yin and yang tonification, water and fire are mutually restricted and mutually promoted, and the ginseng and Chinese angelica are nourished but not dried and moistened but not cooled. The sea-buckthorn is rich in nutrition, contains various vitamins and more than one hundred bioactive substances, provides a nutritional raw material for qi and blood generation, has the functions of slightly activating blood circulation to dissipate blood stasis, dredging channels and collaterals with the towel gourd and promoting blood circulation, is matched with onion medicine-food homology to stimulate yang qi, is beneficial to qi and blood circulation and distribution of the whole body, nourishes the five internal organs and six internal organs, promotes qi and blood generation of the organism, forms virtuous circulation, and enables qi and blood to be supplemented without stagnation and distributed on the whole body, and is a messenger medicine. The ten medicines are all homologous in medicine and food, are matched with each other through a delicate formula, and are mutually matched with each other, and monarch, minister, assistant and guide, the traditional Chinese medicine composition has the obvious effects of tonifying qi and blood, strengthening the spleen and stomach, tonifying deficiency, strengthening the body and improving immunity, and has obvious effects on dizziness, weakness, fatigue, weakness, postpartum postoperative recovery and low immunity caused by deficiency of qi and blood.
Practical cases
In order to scientifically and accurately confirm the treatment effect of the traditional Chinese medicine formula product on the deficiency of qi and blood of men, women, old, young and weak bodies and obvious treatment effect, a part of complete data cases treated by the inventor in 3 years are counted, 128 cases of clinical observation are counted, and the medical history, the state of illness, the age and the original treatment method are recorded for treatment effect verification.
General data
Total 128, 30 men and 98 women; 12 years old, 71 years old with the largest age, and 42 years old on average; all have symptoms of dizziness, hypodynamia, weak constitution and fatigue. Wherein the blood pressure is 45 persons with lower blood pressure, the spleen and stomach are weak, the stool is 43 persons with loose stools, the palpitation is 35 persons with short breath, the fat person is 10 persons, the thin person is 43 persons, the poor appetite is 33 persons, the memory is reduced 49 persons, the limb end is cold 42 persons, the menstrual flow is 35 persons, the faint person is 9 persons who have suffered from faint, the mild anemia is 8 persons, and the blood sugar is 4 persons with lower blood sugar. The shortest disease course is 4 months, the longest disease course is 51 years, and the average disease onset time of the population is 15 years.
Diagnostic criteria
Dialectically diagnosing deficiency of qi and blood according to the Chinese medicine basic diagnosis typing standard of the people's republic of China. Hypotension is based on the diagnosis standard of the world health organization on blood pressure: except for organic lesions, high pressure below 90mmHg or low pressure below 60 mmHg.
Standard of cure
Dizziness, hypodynamia and other symptoms disappear, or the blood pressure of a hypotensive patient is higher than 90/60 mmHg, and the relapse does not occur in half a follow-up year; the effective standard is as follows: the symptoms are basically eliminated and obviously improved or various symptoms are mostly eliminated, and the blood pressure of hypotension patients is increased but not higher than 90/60 mmHg. Invalidation criteria: physical symptoms and blood pressure did not improve at all.
Therapeutic results
The treatment time is 3 months, wherein 115 patients are cured, 11 patients are effective, 2 patients are ineffective, the total effective rate of the treatment result is 98.4%, and the total cure rate is 89.8%. The traditional Chinese medicine formula and the preparation method of the invention are proved to have good effects on the related diseases such as deficiency of qi and blood, weak constitution, hypotension and the like.
Typical case 1
In a female, the female is 32 years old, and the symptoms are aggravated after cesarean section 3 years ago, due to frequent dizziness and hypodynamia for 13 years. The people like to lie and sit, have the symptoms of memory loss and cold limbs, often suffer from palpitation and shortness of breath, no abdominal pain and diarrhea, no cough and asthma, normal body temperature, difficulty in falling asleep and waking up easily, mental fatigue, lassitude, qi deficiency and no speaking desire, loose food and stool, less irregular menstrual period and frigidity. Blood pressure: 70/50 mmHg, normal blood, normal urine, blood ASO (I), ECG showing myocardial ischemia, CT examination of chest normal, color ultrasound of brain normal. The tongue is pale red, the coating is white and has no teeth mark, the face is sallow and the pulse is weak. Traditional Chinese medicine diagnosis: deficiency of qi and blood, hypotension. Syndrome differentiation: deficiency of both qi and blood, weakness of the spleen and stomach. Prescription: the granules obtained by the ten formula and the preparation method are taken with warm boiled water in the morning and at night in a bag of 5 g. After 10 days of administration, the symptoms are relieved, and the blood pressure: 85/55 mmHg. After the patient is continuously taken for 3 months, the disease disappears and the mental state is good. Blood pressure: 95/60 mmHg, and the electrocardiogram is normal after rechecking. After half a year, all the people are normal.
Typical case 2
Wei and Yi, women, age 26, primary school teachers, dizziness, fatigue for 5 years, emaciation, poor appetite, loose stool, occasional palpitation, short breath, cold limbs, little menstrual lead, light color, poor spirit, emotional sadness and heavy psychological burden. The symptoms are aggravated in summer and alleviated in winter, and the symptoms are obviously aggravated every time of cold and enteritis. Once treated by many hospitals, the disease has been diagnosed as coronary heart disease, cerebral circulation insufficiency, neurosis, vegetative nerve functional disturbance and poor curative effect. The diagnosis and treatment of this hospital are introduced by friends. The hematuria is normal, the blood ASO (I), the electrocardiogram shows myocardial ischemia, the chest CT is normal, and the cerebral color Doppler ultrasound shows cerebral ischemia. Pale complexion, pale tongue with white coating, thin and weak pulse, blood pressure: 95/65 mmHg. Traditional Chinese medicine diagnosis: deficiency of both qi and blood, weakness of the spleen and stomach. The treatment mainly comprises the functions of benefiting qi and nourishing blood, strengthening spleen and replenishing vital essence, and activating yang and activating collaterals. Prescription: the granules obtained by the ten formula and the preparation method are taken with warm boiled water in the morning and at night in a bag of 5 g. After the medicine is taken for 16 days, the symptoms are greatly relieved, the dizziness and the fatigue are improved, and the mental state is improved. After the patient is continuously taken for 3 months, the disease disappears, the mental state is good, and the normal mood of the diet is good. The electrocardiogram is normal after rechecking, the color Doppler ultrasound shows that the blood supply of the brain is normal, and all the patients are normal after half a year of return visit.

Claims (3)

1. The traditional Chinese medicine formula for tonifying qi and blood is characterized in that the raw material medicines of the composition are as follows in parts by weight: 2-6 parts of polygonatum odoratum, 2-6 parts of mulberry, 2-6 parts of poria cocos, 2-6 parts of sea buckthorn, 2-6 parts of rhizoma polygonati, 1-5 parts of angelica sinensis, 1-5 parts of raspberry, 1-4 parts of towel gourd, 1-4 parts of onion and 1-2 parts of ginseng.
2. The traditional Chinese medicine formula for replenishing qi and blood according to claim 1, is characterized by comprising the following components in parts by weight: 3 parts of polygonatum, 3 parts of mulberry, 3 parts of poria cocos, 3 parts of sea-buckthorn, 3 parts of rhizoma polygonati, 2 parts of angelica sinensis, 2 parts of raspberry, 3 parts of towel gourd, 3 parts of onion and 1 part of ginseng.
3. The method for preparing a traditional Chinese medicine formula for replenishing qi and blood according to claim 1, wherein 2-6 parts of polygonatum odoratum, 2-6 parts of mulberry, 2-6 parts of poria cocos, 2-6 parts of sea buckthorn, 2-6 parts of rhizoma polygonati, 1-5 parts of angelica sinensis, 1-5 parts of raspberry, 1-4 parts of towel gourd, 1-4 parts of onion and 1-2 parts of ginseng are weighed; selecting, cleaning and uniformly mixing, adding water in an amount which is 2 times of the total amount of the raw materials, decocting at 100-120 ℃ for 1-2 hours, collecting filtrate, filtering out medicine residues, adding appropriate amount of water, boiling with strong fire, adding water for decocting twice, filtering, and combining decoctions obtained in the two times; concentrating the extract at 100-140 ℃, further drying the extract, preparing the extract into 10-12 mesh granules by a granulator, drying the granules at 50-60 ℃, and sieving and granulating the granules to obtain the granules.
CN201910991006.2A 2019-10-18 2019-10-18 Traditional Chinese medicine formula for tonifying qi and blood and preparation method thereof Pending CN110585337A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309918A (en) * 2016-09-30 2017-01-11 四川雄者酒业有限公司 Qi-invigorating and blood-nourishing traditional Chinese medicine composition, and preparation method and application thereof
CN106867826A (en) * 2017-04-24 2017-06-20 成都圣弘源生物科技有限公司 A kind of seabuckthorn wine and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309918A (en) * 2016-09-30 2017-01-11 四川雄者酒业有限公司 Qi-invigorating and blood-nourishing traditional Chinese medicine composition, and preparation method and application thereof
CN106867826A (en) * 2017-04-24 2017-06-20 成都圣弘源生物科技有限公司 A kind of seabuckthorn wine and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
孙朋付等: "细胞N次方治疗低血压气血不足136例疗效分析", 《中西医结合心血管病杂志》 *
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Application publication date: 20191220

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