CN110575578A

CN110575578A - Oxygenator with enhanced exhaust function

Info

Publication number: CN110575578A
Application number: CN201810584470.5A
Authority: CN
Inventors: 魏信鑫; 林伟东; 胡吉龙; 刘三强; 熊斌
Original assignee: Dongguan Kewei Medical Instrument Co Ltd
Current assignee: Dongguan Kewei Medical Instrument Co Ltd
Priority date: 2018-06-08
Filing date: 2018-06-08
Publication date: 2019-12-17
Anticipated expiration: 2038-06-08
Also published as: CN110575578B

Abstract

The application discloses area reinforcing exhausting function's oxygenator, it includes lower cover, oxygenation portion and upper cover, upper cover and lower cover set up in the both ends of oxygenation portion, and the upper cover has into the blood vessel, and it has the blood inlet and the exhaust hole that correspond oxygenation portion to advance the blood vessel, and the exhaust hole is equipped with waterproof ventilated membrane, and waterproof ventilated membrane has a plurality of bleeder vents, and the aperture of each bleeder vent is less than the particle diameter of blood particle to be greater than the particle diameter of gas particle. This application is equipped with waterproof ventilated membrane through the exhaust hole at the upper cover, strengthens the exhaust function of oxygenator, prevents effectively that blood from leaking from the exhaust hole, maintains the blood volume of pouring into.

Description

Oxygenator with enhanced exhaust function

Technical Field

The invention relates to the technical field of medical appliance products, in particular to an oxygenator with an enhanced exhaust function.

Background

The membrane oxygenator is a medical appliance for replacing lungs with cardiac arrest, has the function of regulating the oxygen and carbon dioxide contents in blood, is a necessary medical appliance for cardiovascular surgery, and is also a necessary medical appliance for treating acute respiratory diseases and waiting for lung transplantation. The principle of the membrane oxygenator is that venous blood in a body is led out of the body, oxygen and carbon dioxide are exchanged to be changed into arterial blood after passing through the membrane oxygenator, and the arterial blood is returned to an arterial system of a patient to maintain the supply of oxygenated blood of visceral organs of the human body, so that the pulmonary function is temporarily replaced in the operation process, and meanwhile, a quiet, bloodless and clear operation environment is provided for doctors so as to facilitate the implementation of the operation.

However, the conventional membrane oxygenator generally adopts a mode that an exhaust port is arranged above a blood outlet or the uppermost part of an oxygenator shell, and simply utilizes the principle that gas floats upwards slightly compared with blood to perform exhaust treatment, so that the exhaust treatment capability of the membrane oxygenator is poor.

The applicant of the present application previously proposed "a membrane oxygenator" in chinese patent application No. 201710817386.9, which on the one hand performs an exhaust treatment directly at the blood inlet through the exhaust port provided in the upper cap, and on the other hand, improves its exhaust treatment capacity at the conventional exhaust port by a spiral action on the blood flow. However, when an abnormality occurs, the instantaneous flow rate or flow rate of blood entering the membrane oxygenator is too high, and the blood may not enter the silk membrane structure in time, so that the blood is likely to overflow from the vent hole of the upper cover. If be connected exhaust hole and blood storage storehouse, with the blood of overflow drainage to blood storage storehouse again, then can be because of the blood is shunted and lead to the pouring capacity of blood to descend, also influence the perfusionist to the judgement of actual pouring capacity simultaneously, influence the operation effect.

Disclosure of Invention

The main purpose of this application is to provide a take oxygenation ware that strengthens exhaust function to there is blood that gets into membrane oxygenator to spill over from the exhaust hole of upper cover easily and lead to the problem such as the perfusion volume decline of blood in the prior art to solve.

In order to solve the above problems, the present application provides an oxygenator with an enhanced ventilation function, which comprises a lower cover, an oxygenation part and an upper cover, wherein the upper cover and the lower cover are arranged at two ends of the oxygenation part, the upper cover is provided with a blood inlet pipe and a vent hole, the blood inlet pipe is provided with a blood inlet communicated with the oxygenation part, and the vent hole is provided with a waterproof breathable film.

According to an embodiment of the present application, the waterproof and breathable membrane is disposed at one end of the vent hole close to the oxygenation part.

According to an embodiment of the present application, the upper cover further comprises a fixing structure, the fixing structure has a vent hole, and the waterproof breathable film covers the vent hole of the fixing structure.

According to an embodiment of the present application, the waterproof breathable film is fixed to the inner wall of the vent hole by bonding or ultrasonic welding.

according to an embodiment of the present application, the waterproof breathable film is a single-layer film or a multilayer film.

According to an embodiment of the application, the flow is around the vent hole in the direction of blood flow into the blood vessel.

According to an embodiment of the present application, the upper cover further includes a fluid control valve, and the fluid control valve is disposed at an end of the exhaust hole away from the oxygenation portion and corresponds to the waterproof breathable membrane.

According to an embodiment of the present application, the fluid control valve includes a valve body and a valve cover, the valve body is disposed in the exhaust hole and has a gap with the exhaust hole, the valve cover covers an end of the exhaust hole away from the oxygenation portion and has a through hole, and the valve body is not separated from the through hole.

According to an embodiment of the present application, the through hole includes a first hole and a second hole connected to the first hole, the first hole is close to the valve body, the second hole is away from the valve body, and the aperture of the opening of the first hole close to the valve body is larger than the aperture of the opening of the first hole connected to the second hole.

According to an embodiment of the present application, the hole wall of the first hole is a slope.

According to an embodiment of the present application, the inclined surface is a plane or an arc surface.

According to an embodiment of the present application, the upper cover further includes a fluid switch, and the fluid switch is disposed at an end of the fluid control valve away from the valve body.

According to an embodiment of the present application, the upper cover further includes a fluid switch, and the fluid switch is disposed at an end of the air vent away from the oxygenation unit.

The application provides another area reinforcing exhaust function's oxygenator, and it includes lower cover, oxygenation portion and upper cover, and upper cover and lower cover set up in the both ends of oxygenation portion, and the upper cover has into the blood vessel, and it has the blood inlet that communicates with oxygenation portion to advance the blood vessel, and the exhaust hole is equipped with fluid control valve, and fluid control valve sets up the one end that deviates from oxygenation portion in the exhaust hole.

According to an embodiment of the present application, the upper cover is further provided with a fixing structure, and the fixing structure is located at an end of the air vent close to the oxygenation part, has a through hole, and is opposite to the fluid control valve.

According to an embodiment of the present application, the fluid control valve includes a valve body and a valve cover, the valve body is disposed in the exhaust hole and has a gap with the exhaust hole, the valve cover covers an end of the exhaust hole away from the oxygenation portion and has a through hole, and the valve body does not separate from the through hole.

According to an embodiment of the application, above-mentioned through-hole includes first hole and connects the second hole of first hole, and first hole is close to the valve body, the second hole deviates from the valve body, the open-ended aperture that first hole is close to the valve body is greater than the open-ended aperture that first hole connects the second hole.

According to an embodiment of the present application, the upper cover further includes a fluid switch, and the fluid switch is disposed at an end of the valve cover away from the valve body.

Drawings

The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:

FIG. 1 is a cross-sectional view of an oxygenator with enhanced venting of a first embodiment of the present application.

Fig. 2 is an enlarged view of the area a in fig. 1.

Fig. 3 is a schematic view of an upper cover of a second embodiment of the present application.

Fig. 4 is a sectional view of an upper cover according to a third embodiment of the present application.

Fig. 5 is a sectional view of an upper cover according to a fourth embodiment of the present application.

Fig. 6 is a sectional view of an upper cover according to a fifth embodiment of the present application.

Fig. 7 is a schematic view of an upper cover of a fifth embodiment of the present application.

Detailed Description

In the following description, numerous implementation details are set forth in order to provide a thorough understanding of the present invention. It should be understood, however, that these implementation details should not be used to limit the application. That is, in some embodiments of the present application, such practical details are not necessary. In addition, some conventional structures and components are shown in simplified schematic form in the drawings.

The terms "first," "second," and the like, as used herein, do not denote any order or importance, nor do they denote any order or importance, but rather are used to distinguish one element from another.

Please refer to fig. 1 and 2, which are a cross-sectional view of an oxygenator with enhanced air discharging function according to a first embodiment of the present application and an enlarged view of a region a in fig. 1; as shown in the drawings, the oxygenator 1 with an enhanced air discharging function according to the present embodiment includes a lower cover 10, an oxygenating unit 11, and an upper cover 12, and the lower cover 10 and the upper cover 12 are provided at both ends of the oxygenating unit 11. The lower cover 10 has an exhaust pipe 101. The oxygenation part 11 comprises a mandrel structure 111, an oxygenation housing 112 and a silk membrane structure 113 arranged between the mandrel structure 111 and the oxygenation housing 112, the oxygenation housing 112 has a blood outlet tube 1121, and the blood outlet tube 1121 is close to the lower cover 10. The upper cover 12 has a blood inlet tube 121, an oxygen inlet tube 122 and an air outlet 1212, the blood inlet tube 121 communicates with the space of the oxygenation part 11 where the mandrel structure 111 is provided, and the oxygen inlet tube 122, the blood outlet tube 1121 and the air outlet tube 101 communicate with the space of the oxygenation part 11 where the filament membrane structure 113 is provided, respectively.

The blood inlet tube 121 has a blood inlet 1211, the blood inlet 1211 corresponds to the core shaft structure 111 of the oxygenation part 11 and is communicated with the oxygenation part 11, and in the embodiment, the exhaust hole 1212 corresponds to the blood inlet 1211. The oxygenator 1 with an enhanced exhaust function according to the present embodiment is characterized in that the exhaust hole 1212 of the upper cover 12 is provided with a waterproof breathable membrane 124, the waterproof breathable membrane 124 has a plurality of ventilation holes 1241, and the pore diameter of each ventilation hole 1241 is larger than the particle diameter of the gas particles and smaller than the particle diameter of the blood particles, so that the waterproof breathable membrane 124 allows only gas to pass through and blocks blood, thereby effectively enhancing the exhaust function and preventing blood from leaking out of the exhaust hole 1212. The waterproof breathable membrane 124 of the present embodiment is located at one end of the vent hole 1212 close to the oxygenation part 11, and is particularly disposed at the opening of the vent hole 1212 close to the oxygenation part 11. The waterproof breathable film 124 of the present embodiment is fixed to the inner wall of the vent hole 1212 by bonding or ultrasonic welding.

In use of the oxygenator with an enhanced ventilation function 1 according to the present embodiment, blood in the extracorporeal blood circuit device enters from the blood inlet tube 121 of the oxygenator with an enhanced ventilation function 1, flows into the mandrel structure 111 from the blood inlet 1211, and diffuses toward the silk membrane structure 113. When blood diffuses into the filament membrane structure 113, oxygen is introduced from the oxygen inlet tube 122 into the filament membrane structure 113 to oxygenate the blood in the filament membrane structure 113, so as to replace carbon dioxide or other gases in the blood, and the carbon dioxide or other gases generated during oxygenation are exhausted from the exhaust tube 103 of the lower cover 10 and the exhaust hole 1212 of the upper cover 12. The oxygenated blood is finally expelled from the outlet tube 1121 of the oxygenation housing 112. When blood enters the blood vessel 121 in a large amount or rapidly, the waterproof breathable film 124 prevents the blood entering the blood vessel 121 from overflowing from the vent 1212, so that the blood perfusion amount is prevented from being reduced.

The waterproof and breathable membrane 124 of this embodiment can be disposed at one end of the vent 1212 close to the oxygenation portion 11, or at one end away from the oxygenation portion 11 or at the middle of the vent 1212. The waterproof breathable film 124 is arranged at the opening of the exhaust hole 1212 near one end of the oxygenation part 11, blood enters from the spiral blood inlet tube 121 and generates a vortex, and gas can directly pass through the waterproof breathable film 124 and rapidly escape from the exhaust hole 1212. Compared with the case that the blood at the end of the oxygenation part 11 or in the middle of the vent 1212 is exhausted through the vent 1212 with smaller tube diameter, the air exhausting effect is better.

The waterproof and breathable film 124 of the present embodiment may be a single-layer film or a multi-layer film, and the aperture of the breathable holes is mainly larger than the particle size of the gas particles and smaller than the particle size of the blood particles, so as to allow the gas to pass through and block the blood from passing through. The upper cover of the present embodiment has a fixing structure 1213, the fixing structure 1213 is disposed in one end of the exhaust hole 1212 close to the oxygenation part 11, the fixing structure 1213 is located at the opening of the exhaust hole 1212 close to the oxygenation part 11 and has a through hole 1214, and the through hole 1214 is used for allowing air to pass through. The waterproof breathable membrane 124 covers the through hole 1214 of the fixing structure 1213. In this embodiment, the waterproof breathable membrane 124 is located below the fixing structure 1213, and when blood entering the blood vessel 121 passes through the waterproof breathable membrane 124, the fixing structure 1213 can block the waterproof breathable membrane 124, so as to prevent the waterproof breathable membrane 124 from being taken away by the blood. Of course, the waterproof breathable film 124 is located above the fixing structure 1213, and the fixing structure 1213 supports the waterproof breathable film 124 to prevent the waterproof breathable film 124 from falling off.

Please refer to fig. 3, which is a schematic diagram of an upper cover according to a second embodiment of the present application; as shown in the figure, the blood inlet tube 121 of the present embodiment is spiral, and the blood flowing direction (shown by the dotted line in the figure) in the blood inlet tube 121 flows around the air outlet hole 1212, so as to avoid the liquid seal phenomenon caused by the direct contact of the blood with the waterproof breathable membrane 124 disposed at the air outlet hole 1212, and thus the waterproof breathable membrane 124 of the present embodiment can continuously treat a certain volume of gas. The blood flow rate of the opening of the vent 1212 close to the oxygenation part is faster than that of the blood in the vent, the contact time between the waterproof breathable film 124 and the blood is not long, and the liquid seal phenomenon is not easy to occur.

Please refer to fig. 4, which is a cross-sectional view of a top cover according to a third embodiment of the present application; as shown in the figure, the upper cover 12 of the present embodiment further includes a fluid control valve 125, and the fluid control valve 125 is disposed at the air vent 1212, is located at an end of the air vent 1212 facing away from the oxygenation portion, and corresponds to the waterproof and breathable membrane 124. The fluid control valve 125 according to this embodiment includes a valve body 1251 and a valve cap 1252, the valve body 1251 is disposed in the exhaust hole 1212, the valve cap 1252 is disposed at an end of the exhaust hole 1212 facing away from the oxygenation portion and has a through hole 1253, the through hole 1253 communicates with the exhaust hole 1212, the valve body 1251 corresponds to the through hole 1253, in other words, the waterproof breathable film 124 is disposed at an opening of the exhaust hole 1212 in the upper cover 12, the valve cap 1252 is disposed at an opening of the exhaust hole 1212 out of the upper cover 12, and the valve body 1251 is disposed between the waterproof breathable film 124 and the valve cap 1252. The valve body 1251 and the wall of the vent 1212 define a gap therebetween through which fluid may pass. The width and length of the valve body 1251 are greater than the diameter of the through hole 1253 of the valve cap 1252, such that the valve body 1251 cannot be disengaged from the through hole 1253, wherein the valve body 1251 is a sphere, cylinder, hemisphere, cone, horn, or other shaped body.

When the upper cover 12 of the present embodiment is used in an oxygenator with an enhanced ventilation function, the waterproof breathable film 124 is generally used to block the leakage of blood from the vent 1212 in a state where the waterproof breathable film 124 can be normally used. When the waterproof air-permeable membrane 124 is damaged and cannot be normally used, the fluid control valve 125 is used to block the blood from flowing out, and when the blood flows to the air vent 1212, the blood pushes the valve body 1251 to move towards the valve cap 1252, so that the valve body 1251 closes the through hole 1253 of the valve cap 1252, and the blood is blocked from flowing out from the through hole 1253 of the valve cap 1252. If the gas flows to the exhaust hole 1212, the gas pushes the valve body 1251 but the valve body 1251 does not close the through hole 1253 of the valve cap 1252, so that the exhaust hole 1212 and the through hole 1253 are still communicated. The gas flows from the gap between the valve body 1251 and the exhaust hole 1212 to the valve cap 1252, and flows out from the through hole 1253 of the valve cap 1252. Of course, the upper cover 12 of the present embodiment can omit the provision of the waterproof air-permeable membrane 124.

Please refer to fig. 5, which is a cross-sectional view of a cover according to a fourth embodiment of the present application; as shown in the figures, the through hole of the valve cap of the above embodiment is a straight hole, and the through hole 1253 of the valve cap 1252 of the embodiment includes a first hole 1253a and a second hole 1253b connected to the first hole 1253a, the first hole 1253a is close to the valve body 1251, and the second hole 1253b is far away from the valve body 1251. The hole wall of the first hole 1253a is an inclined surface, and the aperture of the opening of the first hole 1253a close to the valve body 1251 is larger than the aperture of the opening of the first hole 1253a connected with the second hole 1253 b. The width and length of the valve body 1251 are smaller than the diameter of the opening of the first hole 1253a near the valve body 1251 and larger than the diameter of the opening of the first hole 1253a connected to the second hole 1253 b. When the fluid control valve 125 of this embodiment is used, blood pushes the valve body 1251 into the first hole 1253a close to the opening of the valve body 1251 and abuts against the inclined surface, which is a flat surface or an arc surface, to close the second hole 1253b and prevent the blood from leaking out of the through hole 1253. Because the hole wall of the first hole 1253a is an inclined surface, the contact area between the valve body 1251 and the hole wall of the first hole 1253a is increased, so that the valve body 1251 can reliably seal the second hole 1253b, and blood is prevented from leaking from the through hole 1253.

Please refer to fig. 6 and 7, which are cross-sectional views of a top cover according to a fifth embodiment of the present application; as shown in the drawings, the upper cover 12 of the present embodiment is different from the upper cover of the above embodiments in that the upper cover 12 is further provided with a fluid switch 126, and the fluid switch 126 is provided at one end of the through hole 1253 of the valve cover 1252 of the fluid control valve 125, which is far from the valve body 1251, and controls opening and closing of the through hole 1253 of the valve cover 1252. When the waterproof breathable film 124 and the fluid control valve 125 both fail, the fluid switch 126 closes the through hole 1253 of the valve cover 1252, and prevents blood from leaking out of the through hole 1253 of the valve cover 1252.

The opening of the valve cap 1252 facing away from the oxygenating portion of the present embodiment has a recess 1254, and the hole wall of the through hole 1253 of the valve cap 1252 has a through hole 1255. The fluid switch 126 includes a rotating body 1261, a protrusion 1262 provided on the rotating body 1261, and a positioning protrusion 1263 provided on the rotating body 1261 and connected to the protrusion 1262, wherein the protrusion 1262 has a groove 1264, and a sidewall of the groove 1264 has a communication through hole 1265. When the fluid switch 126 is attached to the through hole 1253 of the valve cap 1252, the protrusion 1262 is inserted into the through hole 1253, the rotating body 1261 is positioned outside the valve cap 1252, and the positioning protrusion 1263 is positioned within the groove 1264. When the rotating body 1261 rotates, the rotating body 1261 drives the positioning protrusions 1263 to rotate in the grooves 1264 by the protrusions 1262. The communication hole 1265 of the fluid switch 126 corresponds to the through hole 1255 of the valve cap 1252, and the through hole 1255, the communication hole 1265, the groove 1264, the through hole 1253 of the valve cap 1252 and the air vent 1212 form a communication condition, so that the blood in the oxygenator with the enhanced air vent function can flow out of the fluid control valve 125. In contrast, the communication through hole 1265 of the fluid switch 126 does not correspond to the through hole 1255 of the valve cap 1252, and the sidewall of the through hole 1253 of the valve cap 1252 closes the communication through hole 1265 of the fluid switch 126, so that the blood in the oxygenator with the enhanced air discharging function can flow out of the fluid control valve 125.

Of course, the upper cover 12 can omit the waterproof and breathable membrane 124, and only the fluid control valve 125 and the fluid switch 126 are provided; or the upper cover 12 can omit the fluid control valve 125, only the waterproof breathable membrane 124 and the fluid switch 126 are provided, and the fluid switch 126 is directly disposed at the end of the vent 1212 away from the oxygenation part 11 to control the opening and closing of the vent 1212, so as to prevent the blood from leaking out of the vent 1212. When the waterproof breathable membrane 124 and the fluid control valve 125 fail, the leakage of blood from the vent 1212 or the through hole 1253 of the upper cover 12 can be prevented by controlling the fluid switch 126.

In summary, according to the technical solution of the present application, the waterproof breathable film or the fluid control valve is disposed at the vent hole of the upper cover, so as to effectively prevent the blood introduced into the oxygenator with the enhanced ventilation function from overflowing from the vent hole or the fluid control valve of the upper cover, and simultaneously, the gas separated from the blood is diffused through the waterproof breathable film or the fluid control valve, thereby effectively enhancing the ventilation function of the oxygenator. The vent hole or the fluid control valve of the upper cover are also provided with a fluid switch, when the waterproof breathable film or the fluid control valve fails, the vent hole or the fluid control valve can be closed through the fluid switch, blood is effectively prevented from overflowing from the vent hole of the upper cover, and the blood perfusion amount is further effectively maintained.

The above description is only an embodiment of the present application, and is not intended to limit the present application. Various modifications and changes may occur to those skilled in the art. Any modification, equivalent replacement, improvement or the like made within the spirit and principle of the present application shall be included in the scope of the claims of the present application.

Claims

1. The oxygenator with the function of enhancing air exhaust comprises a lower cover, an oxygenation part and an upper cover, wherein the upper cover and the lower cover are arranged at two ends of the oxygenation part.

2. The oxygenator with an enhanced air venting function as claimed in claim 1, wherein said waterproof air permeable membrane is disposed at one end of said air vent near said oxygenation section.

3. The oxygenator with an enhanced air venting function as claimed in claim 1 or 2, wherein the upper cover is further provided with a fixing structure having a vent hole, and the waterproof vent film covers the vent hole of the fixing structure.

4. The oxygenator with an enhanced air venting function as claimed in claim 1, wherein said waterproof air permeable membrane is fixed to an inner wall of said air vent hole by bonding or ultrasonic welding.

5. The oxygenator with an enhanced air venting function as claimed in claim 1, wherein the upper cover further comprises a fluid control valve disposed at an end of the air vent facing away from the oxygenation portion and corresponding to the waterproof air permeable membrane.

6. The oxygenator with enhanced venting function of claim 5 wherein the upper cover further includes a fluid switch disposed at an end of the fluid control valve distal from the valve body.

7. The oxygenator with enhanced venting function of claim 1 wherein the upper cover further includes a fluid switch disposed at an end of the vent facing away from the oxygenation section.

8. The oxygenator with the function of enhancing air exhaust comprises a lower cover, an oxygenation part and an upper cover, wherein the upper cover and the lower cover are arranged at two ends of the oxygenation part, and is characterized in that the upper cover is provided with an air inlet pipe and an air exhaust hole, the air inlet pipe is provided with a blood inlet communicated with the oxygenation part, the air exhaust hole is provided with a fluid control valve, and the fluid control valve is arranged at one end, deviating from the oxygenation part, of the air exhaust hole.

9. The oxygenator with an enhanced air exhausting function as claimed in claim 8, wherein the upper cover is further provided with a fixing structure which is located at one end of the air exhausting hole close to the oxygenating part and has a through hole, and the fixing structure is opposite to the fluid control valve.

10. The oxygenator with enhanced venting function of claim 8 wherein the upper cover further includes a fluid switch disposed at an end of the fluid control valve distal from the valve body.