CN110520154B - 多价肺炎链球菌疫苗组合物 - Google Patents

多价肺炎链球菌疫苗组合物 Download PDF

Info

Publication number
CN110520154B
CN110520154B CN201880025013.0A CN201880025013A CN110520154B CN 110520154 B CN110520154 B CN 110520154B CN 201880025013 A CN201880025013 A CN 201880025013A CN 110520154 B CN110520154 B CN 110520154B
Authority
CN
China
Prior art keywords
streptococcus pneumoniae
polysaccharide
vaccine composition
protein
capsular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201880025013.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN110520154A (zh
Inventor
赵成济
崔淑英
朴惠梶
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LG Chem Ltd
Original Assignee
LG Chem Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LG Chem Ltd filed Critical LG Chem Ltd
Publication of CN110520154A publication Critical patent/CN110520154A/zh
Application granted granted Critical
Publication of CN110520154B publication Critical patent/CN110520154B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201880025013.0A 2017-03-15 2018-03-14 多价肺炎链球菌疫苗组合物 Active CN110520154B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2017-0032643 2017-03-15
KR20170032643 2017-03-15
PCT/KR2018/002983 WO2018169303A1 (ko) 2017-03-15 2018-03-14 다가 폐렴구균 백신 조성물

Publications (2)

Publication Number Publication Date
CN110520154A CN110520154A (zh) 2019-11-29
CN110520154B true CN110520154B (zh) 2023-08-04

Family

ID=63523679

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880025013.0A Active CN110520154B (zh) 2017-03-15 2018-03-14 多价肺炎链球菌疫苗组合物

Country Status (3)

Country Link
KR (1) KR102101879B1 (ko)
CN (1) CN110520154B (ko)
WO (1) WO2018169303A1 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2936378A1 (en) * 2015-07-21 2017-01-21 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof
KR102573200B1 (ko) 2017-12-06 2023-08-31 머크 샤프 앤드 돔 엘엘씨 스트렙토코쿠스 뉴모니아에 폴리사카라이드-단백질접합체를 포함하는 조성물 및 그의 사용 방법
CN111989114A (zh) * 2018-04-18 2020-11-24 Sk生物科学株式会社 肺炎链球菌的荚膜多糖以及其免疫原性缀合物
PE20211888A1 (es) 2018-12-19 2021-09-22 Merck Sharp & Dohme Composiciones que comprenden conjugados de polisacarido de streptococcus pneumoniae con proteina y sus metodos de uso
KR20210010412A (ko) * 2019-07-18 2021-01-27 (주)셀트리온 다가 폐렴구균 다당류-단백질 접합체를 포함하는 면역원성 조성물
KR20220018939A (ko) * 2020-08-07 2022-02-15 (주)셀트리온 폐렴구균 다당류-세포벽 유래 물질 접합체를 포함하는 면역원성 조성물
CN114544841A (zh) * 2020-11-24 2022-05-27 湘潭智联技术转移促进有限责任公司 一种采用高效液相色谱法测定肺炎球菌多糖-蛋白结合疫苗中dmap残留量的方法
KR20220102871A (ko) * 2021-01-14 2022-07-21 (주)셀트리온 다가 폐렴구균 다당류-단백질 접합체를 포함하는 면역원성 조성물
CN113173977B (zh) * 2021-05-12 2024-03-29 江苏坤力生物制药有限责任公司 一种双功能抗原、其制备方法及应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1391481A (zh) * 1999-03-19 2003-01-15 史密丝克莱恩比彻姆生物有限公司 疫苗
CN101287488A (zh) * 2005-09-01 2008-10-15 诺华疫苗和诊断有限两合公司 含血清群c脑膜炎球菌的多价疫苗
CN101785857A (zh) * 2010-03-05 2010-07-28 郑玉清 一种新的肺炎球菌结合疫苗及其制备方法
CN102933229A (zh) * 2010-06-04 2013-02-13 惠氏有限责任公司 疫苗制剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013171661A2 (en) * 2012-05-15 2013-11-21 Subhash V Kapre Adjuvant formulations and methods
CN103893751B (zh) * 2014-03-26 2016-04-20 天津康希诺生物技术有限公司 一种肺炎球菌多糖蛋白缀合疫苗及其制备方法
CN104069504B (zh) * 2014-05-11 2019-09-24 江苏康泰生物医学技术有限公司 一种增强多糖蛋白结合物免疫原性的方法
BR112018005291A2 (pt) * 2015-09-16 2018-10-09 Lg Chemical Ltd composição para vacina combinada para dosagem múltipla

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1391481A (zh) * 1999-03-19 2003-01-15 史密丝克莱恩比彻姆生物有限公司 疫苗
CN101287488A (zh) * 2005-09-01 2008-10-15 诺华疫苗和诊断有限两合公司 含血清群c脑膜炎球菌的多价疫苗
CN101785857A (zh) * 2010-03-05 2010-07-28 郑玉清 一种新的肺炎球菌结合疫苗及其制备方法
CN102933229A (zh) * 2010-06-04 2013-02-13 惠氏有限责任公司 疫苗制剂

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刁连东 主编.美国已批准使用疫苗中包含的赋形剂.《实用疫苗学》.上海科学技术出版社,2015,第31-32页. *

Also Published As

Publication number Publication date
KR20180105590A (ko) 2018-09-28
KR102101879B1 (ko) 2020-05-29
CN110520154A (zh) 2019-11-29
WO2018169303A1 (ko) 2018-09-20

Similar Documents

Publication Publication Date Title
CN110520154B (zh) 多价肺炎链球菌疫苗组合物
US10058607B2 (en) Polyvalent pneumococcal polysaccharide-protein conjugate composition
TWI511739B (zh) 多價肺炎球菌多醣-蛋白質共軛物組合物
KR101511392B1 (ko) 다가 폐렴구균 다당류-단백질 접합체 조성물
KR101511393B1 (ko) 다가 폐렴구균 다당류-단백질 접합체 조성물
JP7030235B2 (ja) 多価肺炎球菌多糖体-タンパク質複合体組成物
KR101538535B1 (ko) 15가 폐렴구균성 폴리사카라이드-단백질 접합체 백신 조성물
US9981029B2 (en) Multivalent pneumococcal polysaccharide-protein conjugate composition
CA2894532C (en) Multivalent pneumococcal polysaccharide-protein conjugate composition
JP2021512870A (ja) 多価肺炎球菌多糖体−タンパク質複合体組成物
KR101991457B1 (ko) 다가 협막 다당류-운반 단백질을 포함하는 조성물 및 이의 용도
KR102083973B1 (ko) 향상된 IgG 역가를 갖는 다가면역원성 조성물 및 이의 용도
KR20200005458A (ko) 다가 폐렴구균 다당체-단백질 접합체를 포함하는 면역원성 조성물, 및 이를 포함하는 약학 조성물
EA041147B1 (ru) Композиция многовалентных пневмококковых конъюгатов капсульного полисахарида с белком-носителем и ее применение
TWI586363B (zh) 多價肺炎球菌多醣-蛋白質共軛物組成物

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40011275

Country of ref document: HK

GR01 Patent grant
GR01 Patent grant