CN110506121A - 含硫羟基的切割试剂和氧化洗涤剂 - Google Patents

含硫羟基的切割试剂和氧化洗涤剂 Download PDF

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Publication number
CN110506121A
CN110506121A CN201780080043.7A CN201780080043A CN110506121A CN 110506121 A CN110506121 A CN 110506121A CN 201780080043 A CN201780080043 A CN 201780080043A CN 110506121 A CN110506121 A CN 110506121A
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CN
China
Prior art keywords
compound
group
cleavage
synthesis
disulfide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201780080043.7A
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English (en)
Chinese (zh)
Inventor
M·S·玛尔玛
L·安德鲁兹
B·麦克纳利
A·德鲁西亚
D·埃夫罗尼
E·卡彭特
M·贝塞夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qi Gang Science Co Ltd
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Qi Gang Science Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/343,279 external-priority patent/US10273539B2/en
Priority claimed from US15/457,344 external-priority patent/US11421264B2/en
Application filed by Qi Gang Science Co Ltd filed Critical Qi Gang Science Co Ltd
Publication of CN110506121A publication Critical patent/CN110506121A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
CN201780080043.7A 2016-11-04 2017-10-28 含硫羟基的切割试剂和氧化洗涤剂 Pending CN110506121A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15/343,279 2016-11-04
US15/343,279 US10273539B2 (en) 2015-11-06 2016-11-04 Methods of using nucleotide analogues
US15/457,344 2017-03-13
US15/457,344 US11421264B2 (en) 2015-11-06 2017-03-13 Thiol-containing cleave reagents and oxidative wash
PCT/US2017/058908 WO2018085156A1 (en) 2016-11-04 2017-10-28 Thiol-containing cleave reagents and oxidative wash

Publications (1)

Publication Number Publication Date
CN110506121A true CN110506121A (zh) 2019-11-26

Family

ID=62076119

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780080043.7A Pending CN110506121A (zh) 2016-11-04 2017-10-28 含硫羟基的切割试剂和氧化洗涤剂

Country Status (6)

Country Link
EP (1) EP3535407B1 (enExample)
JP (1) JP7091325B2 (enExample)
CN (1) CN110506121A (enExample)
AU (1) AU2017354876A1 (enExample)
CA (1) CA3041055A1 (enExample)
WO (1) WO2018085156A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114031476A (zh) * 2021-11-23 2022-02-11 北京中医药大学 一种将甲硫基亚甲基氧衍生物转化为羟基化合物的绿色方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113453692A (zh) * 2019-01-08 2021-09-28 奇异基因组学系统公司 核苷酸可裂解接头和其用途
GB2580963C (en) * 2019-02-01 2025-09-03 Hemispherian As Cancer therapies

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO873956D0 (no) * 1986-09-25 1987-09-22 Bp Chem Int Ltd Rensemidler inneholdende peroksyder for fjerning av flyktige sulfider.
US6046039A (en) * 1998-08-19 2000-04-04 Battelle Memorial Institute Methods for producing partially digested restriction DNA fragments and for producing a partially modified PCR product
US6440705B1 (en) * 1998-10-01 2002-08-27 Vincent P. Stanton, Jr. Method for analyzing polynucleotides
US20030092763A1 (en) * 1999-11-10 2003-05-15 Snezna Rogelj Method for induction of L-selectin shedding
US6566059B1 (en) * 1998-10-01 2003-05-20 Variagenics, Inc. Method for analyzing polynucleotides
US20100209908A1 (en) * 2007-12-18 2010-08-19 Procop Gary W System and method for nucleotide sequence profiling for sample identification
EP2305835A1 (en) * 2009-09-29 2011-04-06 Korea Institute of Science and Technology 3'-O-Fluorescently modified nucleotides and uses thereof
WO2012149472A2 (en) * 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
WO2015006811A2 (en) * 2013-07-19 2015-01-22 The Walter And Eliza Hall Institute Of Medical Research Diagnostic methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465628B1 (en) * 1999-02-04 2002-10-15 Isis Pharmaceuticals, Inc. Process for the synthesis of oligomeric compounds
US6309836B1 (en) 1999-10-05 2001-10-30 Marek Kwiatkowski Compounds for protecting hydroxyls and methods for their use
US7057026B2 (en) 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
EP1495137B1 (en) 2002-04-04 2005-09-14 Biotage AB Primer extension based method employing nucleotides labelled via cleavable linkers
US8481259B2 (en) * 2007-02-05 2013-07-09 Intelligent Bio-Systems, Inc. Methods and devices for sequencing nucleic acids in smaller batches
US20100330569A1 (en) 2009-04-23 2010-12-30 Intelligent Bio-Systems, Inc. Hydroxymethyl Linkers For Labeling Nucleotides
EP2876166B1 (en) 2013-11-20 2016-12-14 Roche Diagnostics GmbH New compound for sequencing by synthesis

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO873956D0 (no) * 1986-09-25 1987-09-22 Bp Chem Int Ltd Rensemidler inneholdende peroksyder for fjerning av flyktige sulfider.
US6046039A (en) * 1998-08-19 2000-04-04 Battelle Memorial Institute Methods for producing partially digested restriction DNA fragments and for producing a partially modified PCR product
US6440705B1 (en) * 1998-10-01 2002-08-27 Vincent P. Stanton, Jr. Method for analyzing polynucleotides
US6566059B1 (en) * 1998-10-01 2003-05-20 Variagenics, Inc. Method for analyzing polynucleotides
US20030092763A1 (en) * 1999-11-10 2003-05-15 Snezna Rogelj Method for induction of L-selectin shedding
US20100209908A1 (en) * 2007-12-18 2010-08-19 Procop Gary W System and method for nucleotide sequence profiling for sample identification
EP2305835A1 (en) * 2009-09-29 2011-04-06 Korea Institute of Science and Technology 3'-O-Fluorescently modified nucleotides and uses thereof
WO2012149472A2 (en) * 2011-04-27 2012-11-01 Ignite Institute For Individualized Health Methods, compositions, and kits for treating and preventing neurological conditions
WO2015006811A2 (en) * 2013-07-19 2015-01-22 The Walter And Eliza Hall Institute Of Medical Research Diagnostic methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GERARDO TURCATTI等: ""A new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesis"", 《NUCLEIC ACIDS RESEARCH》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114031476A (zh) * 2021-11-23 2022-02-11 北京中医药大学 一种将甲硫基亚甲基氧衍生物转化为羟基化合物的绿色方法

Also Published As

Publication number Publication date
JP2019536448A (ja) 2019-12-19
EP3535407A1 (en) 2019-09-11
EP3535407B1 (en) 2021-06-02
WO2018085156A1 (en) 2018-05-11
EP3535407A4 (en) 2020-06-24
CA3041055A1 (en) 2018-05-11
JP7091325B2 (ja) 2022-06-27
AU2017354876A1 (en) 2019-06-20

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Application publication date: 20191126