CN110494118A - The method of product composition of the preparation comprising discrete particle and aqueous base composition - Google Patents
The method of product composition of the preparation comprising discrete particle and aqueous base composition Download PDFInfo
- Publication number
- CN110494118A CN110494118A CN201880024653.XA CN201880024653A CN110494118A CN 110494118 A CN110494118 A CN 110494118A CN 201880024653 A CN201880024653 A CN 201880024653A CN 110494118 A CN110494118 A CN 110494118A
- Authority
- CN
- China
- Prior art keywords
- composition
- discrete particle
- surfactant
- group
- aqueous base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 539
- 239000002245 particle Substances 0.000 title claims abstract description 122
- 238000000034 method Methods 0.000 title claims abstract description 68
- 238000002360 preparation method Methods 0.000 title description 6
- 150000001875 compounds Chemical class 0.000 claims abstract description 107
- 230000009286 beneficial effect Effects 0.000 claims abstract description 85
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 83
- 239000004094 surface-active agent Substances 0.000 claims abstract description 77
- 229940116364 hard fat Drugs 0.000 claims abstract description 67
- 239000008365 aqueous carrier Substances 0.000 claims abstract description 22
- 229920003169 water-soluble polymer Polymers 0.000 claims abstract description 22
- 239000002280 amphoteric surfactant Substances 0.000 claims abstract description 7
- 239000002888 zwitterionic surfactant Substances 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 47
- 238000002156 mixing Methods 0.000 claims description 40
- 238000002844 melting Methods 0.000 claims description 23
- 239000003093 cationic surfactant Substances 0.000 claims description 22
- 229920000642 polymer Polymers 0.000 claims description 22
- 229920001296 polysiloxane Polymers 0.000 claims description 22
- 230000008018 melting Effects 0.000 claims description 20
- 239000000126 substance Substances 0.000 claims description 15
- 230000008961 swelling Effects 0.000 claims description 15
- 239000004615 ingredient Substances 0.000 claims description 14
- 239000003153 chemical reaction reagent Substances 0.000 claims description 10
- 239000003086 colorant Substances 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 9
- 239000007787 solid Substances 0.000 claims description 8
- 230000003213 activating effect Effects 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 150000001450 anions Chemical class 0.000 claims description 5
- 244000027321 Lychnis chalcedonica Species 0.000 claims description 4
- 150000001768 cations Chemical class 0.000 claims description 4
- 230000002209 hydrophobic effect Effects 0.000 claims description 3
- 239000002736 nonionic surfactant Substances 0.000 claims description 3
- 239000007764 o/w emulsion Substances 0.000 claims description 3
- 239000007762 w/o emulsion Substances 0.000 claims description 3
- 238000003825 pressing Methods 0.000 claims 2
- 239000002304 perfume Substances 0.000 claims 1
- 235000013599 spices Nutrition 0.000 claims 1
- 230000008021 deposition Effects 0.000 abstract description 9
- 239000003945 anionic surfactant Substances 0.000 abstract description 7
- 230000008569 process Effects 0.000 abstract description 3
- 239000000047 product Substances 0.000 description 82
- -1 polyoxyethylene Polymers 0.000 description 47
- 125000000217 alkyl group Chemical group 0.000 description 43
- 125000004432 carbon atom Chemical group C* 0.000 description 26
- 239000002253 acid Substances 0.000 description 18
- 229910052799 carbon Inorganic materials 0.000 description 17
- 150000002191 fatty alcohols Chemical class 0.000 description 15
- 239000007788 liquid Substances 0.000 description 14
- 150000003863 ammonium salts Chemical class 0.000 description 13
- 125000003118 aryl group Chemical group 0.000 description 13
- 230000003750 conditioning effect Effects 0.000 description 13
- 229920001577 copolymer Polymers 0.000 description 13
- 239000003205 fragrance Substances 0.000 description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 12
- 150000001721 carbon Chemical group 0.000 description 12
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 12
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 11
- 125000001453 quaternary ammonium group Chemical group 0.000 description 11
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
- 229920013822 aminosilicone Polymers 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 230000008859 change Effects 0.000 description 8
- 150000002148 esters Chemical class 0.000 description 8
- 235000019441 ethanol Nutrition 0.000 description 8
- 239000006210 lotion Substances 0.000 description 8
- 229920002379 silicone rubber Polymers 0.000 description 8
- 230000008719 thickening Effects 0.000 description 8
- 150000001732 carboxylic acid derivatives Chemical class 0.000 description 7
- 125000004185 ester group Chemical group 0.000 description 7
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 6
- 125000001931 aliphatic group Chemical group 0.000 description 6
- 125000003368 amide group Chemical group 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- HOWGUJZVBDQJKV-UHFFFAOYSA-N docosane Chemical compound CCCCCCCCCCCCCCCCCCCCCC HOWGUJZVBDQJKV-UHFFFAOYSA-N 0.000 description 6
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 6
- 239000003921 oil Substances 0.000 description 6
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 6
- 239000004215 Carbon black (E152) Substances 0.000 description 5
- 239000004721 Polyphenylene oxide Substances 0.000 description 5
- 125000003545 alkoxy group Chemical group 0.000 description 5
- 150000001412 amines Chemical class 0.000 description 5
- 230000008901 benefit Effects 0.000 description 5
- 125000002091 cationic group Chemical group 0.000 description 5
- 150000002430 hydrocarbons Chemical group 0.000 description 5
- 125000002768 hydroxyalkyl group Chemical group 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 229920000570 polyether Polymers 0.000 description 5
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
- 102000011782 Keratins Human genes 0.000 description 4
- 108010076876 Keratins Proteins 0.000 description 4
- 150000001335 aliphatic alkanes Chemical class 0.000 description 4
- 125000000524 functional group Chemical group 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 229930195733 hydrocarbon Natural products 0.000 description 4
- 229910052739 hydrogen Inorganic materials 0.000 description 4
- 239000001257 hydrogen Substances 0.000 description 4
- CBFCDTFDPHXCNY-UHFFFAOYSA-N icosane Chemical compound CCCCCCCCCCCCCCCCCCCC CBFCDTFDPHXCNY-UHFFFAOYSA-N 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 229920000233 poly(alkylene oxides) Polymers 0.000 description 4
- 229920001281 polyalkylene Polymers 0.000 description 4
- 229920006395 saturated elastomer Polymers 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 3
- 229940126062 Compound A Drugs 0.000 description 3
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
- 238000005481 NMR spectroscopy Methods 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 235000010489 acacia gum Nutrition 0.000 description 3
- 239000011149 active material Substances 0.000 description 3
- 150000003973 alkyl amines Chemical class 0.000 description 3
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 3
- 125000003277 amino group Chemical group 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 229960000541 cetyl alcohol Drugs 0.000 description 3
- 239000000470 constituent Substances 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 239000000194 fatty acid Chemical class 0.000 description 3
- 229930195729 fatty acid Chemical class 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 229910052736 halogen Inorganic materials 0.000 description 3
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 229910052500 inorganic mineral Inorganic materials 0.000 description 3
- 239000010445 mica Substances 0.000 description 3
- 229910052618 mica group Inorganic materials 0.000 description 3
- 239000011707 mineral Substances 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- 125000000962 organic group Chemical group 0.000 description 3
- 229920002553 poly(2-methacrylolyloxyethyltrimethylammonium chloride) polymer Polymers 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- 239000003760 tallow Substances 0.000 description 3
- 239000003981 vehicle Substances 0.000 description 3
- 125000002733 (C1-C6) fluoroalkyl group Chemical group 0.000 description 2
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical group N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 2
- 244000131522 Citrus pyriformis Species 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 2
- 108010035532 Collagen Proteins 0.000 description 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- 229920000084 Gum arabic Polymers 0.000 description 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- 229920000289 Polyquaternium Polymers 0.000 description 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 2
- 239000000205 acacia gum Substances 0.000 description 2
- 238000005054 agglomeration Methods 0.000 description 2
- 230000002776 aggregation Effects 0.000 description 2
- 125000002877 alkyl aryl group Chemical group 0.000 description 2
- 150000008051 alkyl sulfates Chemical class 0.000 description 2
- 125000005233 alkylalcohol group Chemical group 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229940006460 bromide ion Drugs 0.000 description 2
- 229910052794 bromium Inorganic materials 0.000 description 2
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229910052801 chlorine Inorganic materials 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000576 coating method Methods 0.000 description 2
- 229920001436 collagen Polymers 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 239000008406 cosmetic ingredient Substances 0.000 description 2
- 238000002425 crystallisation Methods 0.000 description 2
- 230000008025 crystallization Effects 0.000 description 2
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 2
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- JBKVHLHDHHXQEQ-UHFFFAOYSA-N epsilon-caprolactam Chemical compound O=C1CCCCCN1 JBKVHLHDHHXQEQ-UHFFFAOYSA-N 0.000 description 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000005227 gel permeation chromatography Methods 0.000 description 2
- 229920000591 gum Polymers 0.000 description 2
- DCAYPVUWAIABOU-UHFFFAOYSA-N hexadecane Chemical compound CCCCCCCCCCCCCCCC DCAYPVUWAIABOU-UHFFFAOYSA-N 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 2
- 229920000554 ionomer Polymers 0.000 description 2
- 229940060384 isostearyl isostearate Drugs 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 239000003094 microcapsule Substances 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- DAZXVJBJRMWXJP-UHFFFAOYSA-N n,n-dimethylethylamine Chemical compound CCN(C)C DAZXVJBJRMWXJP-UHFFFAOYSA-N 0.000 description 2
- MWKFXSUHUHTGQN-UHFFFAOYSA-N n-decyl alcohol Natural products CCCCCCCCCCO MWKFXSUHUHTGQN-UHFFFAOYSA-N 0.000 description 2
- MVAOLFCQWQECDS-UHFFFAOYSA-N n-ethylpentan-2-amine Chemical compound CCCC(C)NCC MVAOLFCQWQECDS-UHFFFAOYSA-N 0.000 description 2
- RZJRJXONCZWCBN-UHFFFAOYSA-N octadecane Chemical compound CCCCCCCCCCCCCCCCCC RZJRJXONCZWCBN-UHFFFAOYSA-N 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000010452 phosphate Substances 0.000 description 2
- 230000010287 polarization Effects 0.000 description 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 2
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 2
- 230000005588 protonation Effects 0.000 description 2
- 235000021251 pulses Nutrition 0.000 description 2
- FGVVTMRZYROCTH-UHFFFAOYSA-N pyridine-2-thiol N-oxide Chemical compound [O-][N+]1=CC=CC=C1S FGVVTMRZYROCTH-UHFFFAOYSA-N 0.000 description 2
- 229960002026 pyrithione Drugs 0.000 description 2
- 230000003252 repetitive effect Effects 0.000 description 2
- 238000000518 rheometry Methods 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 229920005573 silicon-containing polymer Polymers 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- BDHFUVZGWQCTTF-UHFFFAOYSA-N sulfonic acid Chemical compound OS(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-N 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- BGHCVCJVXZWKCC-UHFFFAOYSA-N tetradecane Chemical compound CCCCCCCCCCCCCC BGHCVCJVXZWKCC-UHFFFAOYSA-N 0.000 description 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
- 229940043810 zinc pyrithione Drugs 0.000 description 2
- PICXIOQBANWBIZ-UHFFFAOYSA-N zinc;1-oxidopyridine-2-thione Chemical compound [Zn+2].[O-]N1C=CC=CC1=S.[O-]N1C=CC=CC1=S PICXIOQBANWBIZ-UHFFFAOYSA-N 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- MRAMPOPITCOOIN-VIFPVBQESA-N (2r)-n-(3-ethoxypropyl)-2,4-dihydroxy-3,3-dimethylbutanamide Chemical compound CCOCCCNC(=O)[C@H](O)C(C)(C)CO MRAMPOPITCOOIN-VIFPVBQESA-N 0.000 description 1
- 125000006659 (C1-C20) hydrocarbyl group Chemical group 0.000 description 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- 238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- ZRNSSRODJSSVEJ-UHFFFAOYSA-N 2-methylpentacosane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCC(C)C ZRNSSRODJSSVEJ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 244000215068 Acacia senegal Species 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 description 1
- 241000195940 Bryophyta Species 0.000 description 1
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 description 1
- BIAOWYXLCJQFDJ-UHFFFAOYSA-N CCCCCCCCCCCCCCCCCC(NCCCC(C)NCC)=O Chemical compound CCCCCCCCCCCCCCCCCC(NCCCC(C)NCC)=O BIAOWYXLCJQFDJ-UHFFFAOYSA-N 0.000 description 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 238000000685 Carr-Purcell-Meiboom-Gill pulse sequence Methods 0.000 description 1
- 108010076119 Caseins Proteins 0.000 description 1
- 240000008886 Ceratonia siliqua Species 0.000 description 1
- 235000013912 Ceratonia siliqua Nutrition 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- 235000005979 Citrus limon Nutrition 0.000 description 1
- 244000303965 Cyamopsis psoralioides Species 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 239000001856 Ethyl cellulose Substances 0.000 description 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- 229920002148 Gellan gum Polymers 0.000 description 1
- 102000051325 Glucagon Human genes 0.000 description 1
- 108060003199 Glucagon Proteins 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 108010068370 Glutens Proteins 0.000 description 1
- 229920002907 Guar gum Polymers 0.000 description 1
- 229920000569 Gum karaya Polymers 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 108010064851 Plant Proteins Proteins 0.000 description 1
- 244000090599 Plantago psyllium Species 0.000 description 1
- 235000010451 Plantago psyllium Nutrition 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002873 Polyethylenimine Polymers 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- UMPVRLNJBRSFTR-UHFFFAOYSA-N S(=O)(=O)(OC)[O-].C(CCCCCCCCCCCCCCCCCCCCC)[NH3+] Chemical compound S(=O)(=O)(OC)[O-].C(CCCCCCCCCCCCCCCCCCCCC)[NH3+] UMPVRLNJBRSFTR-UHFFFAOYSA-N 0.000 description 1
- 229920001800 Shellac Polymers 0.000 description 1
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000934878 Sterculia Species 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 229920002494 Zein Polymers 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 235000010419 agar Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 150000007824 aliphatic compounds Chemical class 0.000 description 1
- 125000003282 alkyl amino group Chemical group 0.000 description 1
- 230000002152 alkylating effect Effects 0.000 description 1
- 125000001118 alkylidene group Chemical group 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 150000001449 anionic compounds Chemical class 0.000 description 1
- 125000000129 anionic group Chemical group 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- HDHICXMXQDZNGS-UHFFFAOYSA-N azanium dimethylazanium dichloride Chemical compound [Cl-].[NH4+].[Cl-].C[NH2+]C HDHICXMXQDZNGS-UHFFFAOYSA-N 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 125000002511 behenyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- RWCCWEUUXYIKHB-UHFFFAOYSA-N benzophenone Chemical compound C=1C=CC=CC=1C(=O)C1=CC=CC=C1 RWCCWEUUXYIKHB-UHFFFAOYSA-N 0.000 description 1
- 239000012965 benzophenone Substances 0.000 description 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
- 125000002619 bicyclic group Chemical group 0.000 description 1
- 230000001588 bifunctional effect Effects 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- 229950010118 cellacefate Drugs 0.000 description 1
- 229920003086 cellulose ether Polymers 0.000 description 1
- 229940059329 chondroitin sulfate Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000007334 copolymerization reaction Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- LDHQCZJRKDOVOX-NSCUHMNNSA-N crotonic acid Chemical compound C\C=C\C(O)=O LDHQCZJRKDOVOX-NSCUHMNNSA-N 0.000 description 1
- 230000001186 cumulative effect Effects 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- UZBQIPPOMKBLAS-UHFFFAOYSA-N diethylazanide Chemical compound CC[N-]CC UZBQIPPOMKBLAS-UHFFFAOYSA-N 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- REZZEXDLIUJMMS-UHFFFAOYSA-M dimethyldioctadecylammonium chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCCCC[N+](C)(C)CCCCCCCCCCCCCCCCCC REZZEXDLIUJMMS-UHFFFAOYSA-M 0.000 description 1
- 229960000735 docosanol Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- XXUJMEYKYHETBZ-UHFFFAOYSA-N ethyl 4-nitrophenyl ethylphosphonate Chemical compound CCOP(=O)(CC)OC1=CC=C([N+]([O-])=O)C=C1 XXUJMEYKYHETBZ-UHFFFAOYSA-N 0.000 description 1
- 235000019325 ethyl cellulose Nutrition 0.000 description 1
- 229920001249 ethyl cellulose Polymers 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 125000001153 fluoro group Chemical group F* 0.000 description 1
- 125000003784 fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 235000010492 gellan gum Nutrition 0.000 description 1
- 239000000216 gellan gum Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 description 1
- 229960004666 glucagon Drugs 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- 235000010417 guar gum Nutrition 0.000 description 1
- 239000000665 guar gum Substances 0.000 description 1
- 229960002154 guar gum Drugs 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 125000003187 heptyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- URXQDXAVUYKSCK-UHFFFAOYSA-N hexadecyl(dimethyl)azanium;chloride Chemical compound [Cl-].CCCCCCCCCCCCCCCC[NH+](C)C URXQDXAVUYKSCK-UHFFFAOYSA-N 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 235000011167 hydrochloric acid Nutrition 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-M hydrogensulfate Chemical compound OS([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-M 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 229920013818 hydroxypropyl guar gum Polymers 0.000 description 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 1
- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 description 1
- 229910001412 inorganic anion Inorganic materials 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 1
- 235000010494 karaya gum Nutrition 0.000 description 1
- 239000000231 karaya gum Substances 0.000 description 1
- 229940039371 karaya gum Drugs 0.000 description 1
- 229940025902 konjac mannan Drugs 0.000 description 1
- 150000003951 lactams Chemical class 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229920000609 methyl cellulose Polymers 0.000 description 1
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 description 1
- JZMJDSHXVKJFKW-UHFFFAOYSA-M methyl sulfate(1-) Chemical compound COS([O-])(=O)=O JZMJDSHXVKJFKW-UHFFFAOYSA-M 0.000 description 1
- XJRBAMWJDBPFIM-UHFFFAOYSA-N methyl vinyl ether Chemical compound COC=C XJRBAMWJDBPFIM-UHFFFAOYSA-N 0.000 description 1
- 235000010981 methylcellulose Nutrition 0.000 description 1
- 239000001923 methylcellulose Substances 0.000 description 1
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 150000002762 monocarboxylic acid derivatives Chemical class 0.000 description 1
- NBVXSUQYWXRMNV-UHFFFAOYSA-N monofluoromethane Natural products FC NBVXSUQYWXRMNV-UHFFFAOYSA-N 0.000 description 1
- 235000011929 mousse Nutrition 0.000 description 1
- ZUHZZVMEUAUWHY-UHFFFAOYSA-N n,n-dimethylpropan-1-amine Chemical compound CCCN(C)C ZUHZZVMEUAUWHY-UHFFFAOYSA-N 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- KKBOOQDFOWZSDC-UHFFFAOYSA-N n-[2-(diethylamino)ethyl]octadecanamide Chemical compound CCCCCCCCCCCCCCCCCC(=O)NCCN(CC)CC KKBOOQDFOWZSDC-UHFFFAOYSA-N 0.000 description 1
- 125000000740 n-pentyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 239000000346 nonvolatile oil Substances 0.000 description 1
- 125000001400 nonyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940038384 octadecane Drugs 0.000 description 1
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 150000002891 organic anions Chemical class 0.000 description 1
- 239000003002 pH adjusting agent Substances 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229940101267 panthenol Drugs 0.000 description 1
- 229940023735 panthenyl ethyl ether Drugs 0.000 description 1
- 235000020957 pantothenol Nutrition 0.000 description 1
- 239000011619 pantothenol Substances 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 125000005004 perfluoroethyl group Chemical group FC(F)(F)C(F)(F)* 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 229960003415 propylparaben Drugs 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 229930195734 saturated hydrocarbon Chemical group 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 150000005619 secondary aliphatic amines Chemical class 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 239000004208 shellac Substances 0.000 description 1
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
- 229940113147 shellac Drugs 0.000 description 1
- 235000013874 shellac Nutrition 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 235000019710 soybean protein Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 125000005323 thioketone group Chemical group 0.000 description 1
- LDHQCZJRKDOVOX-UHFFFAOYSA-N trans-crotonic acid Natural products CC=CC(O)=O LDHQCZJRKDOVOX-UHFFFAOYSA-N 0.000 description 1
- 125000000725 trifluoropropyl group Chemical group [H]C([H])(*)C([H])([H])C(F)(F)F 0.000 description 1
- PDSVZUAJOIQXRK-UHFFFAOYSA-N trimethyl(octadecyl)azanium Chemical class CCCCCCCCCCCCCCCCCC[N+](C)(C)C PDSVZUAJOIQXRK-UHFFFAOYSA-N 0.000 description 1
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000021119 whey protein Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- 239000005019 zein Substances 0.000 description 1
- 229940093612 zein Drugs 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/044—Suspensions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
- A61K8/585—Organosilicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/87—Polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/896—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate
- A61K8/898—Polysiloxanes containing atoms other than silicon, carbon, oxygen and hydrogen, e.g. dimethicone copolyol phosphate containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/90—Block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/42—Colour properties
- A61K2800/43—Pigments; Dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/60—Particulates further characterized by their structure or composition
- A61K2800/65—Characterized by the composition of the particulate/core
- A61K2800/652—The particulate/core comprising organic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Abstract
The invention discloses a kind of methods for preparing product composition, method includes the following steps: preparing blend composition, which includes surfactant and hard fat compounds of group and beneficial agent;Aqueous base composition is prepared separately, the aqueous base composition includes aqueous carrier and water-soluble polymer, wherein base composition is selected from substantially free of detersive surfactant, the detersive surfactant: anionic surfactant, zwitterionic surfactant, amphoteric surfactant and their combination;Blend composition is mixed with aqueous base composition, to form the discrete particle for the blend composition being scattered in aqueous base composition.Alternatively, method includes the following steps: preparing the discrete particle of blend composition;And the discrete particle is mixed with Aquo-composition.The inventive process provides the product compositions at least one of the following: the greater flexibility of product mix rheological;The improved stability of product composition;The improved deposition of beneficial agent;And improved vision/aesthetic appearance.
Description
Technical field
The present invention relates to a kind of methods for preparing product composition, method includes the following steps: preparing mixture combination
Object, the blend composition include surfactant and hard fat compounds of group and beneficial agent;It is prepared separately containing water base
Plinth composition, the aqueous base composition include aqueous carrier and water-soluble polymer, wherein base composition substantially free of
Detersive surfactant, the detersive surfactant are selected from anionic surfactant, zwitterionic surfactant, both sexes table
Face activating agent and their combination;Blend composition is mixed with aqueous base composition, is scattered in being formed containing water base
The discrete particle of blend composition in plinth composition.Alternatively, method includes the following steps: preparing blend composition
Discrete particle;And the discrete particle is mixed with Aquo-composition.The inventive process provides in following extremely
A kind of few product composition: the greater flexibility of product mix rheological;The improved stability of product composition;Have
The improved deposition of beneficial agent;And improved vision/aesthetic appearance.
Background technique
It has developed a variety of methods and has carried out conditioning hair.It is a kind of provide conditioning beneficial effect common method be by using
Conditioner, such as cationic surfactant and polymer, hard fat compounds of group, low melting point oil, silicone compounds,
And their mixture.These known most of conditioners provide various conditioning beneficial effects.
For example, the U.S. Patent Application Publication No. 2003/0103923 from SAN-EI KAGAKU is related to the group comprising alcohol
Object is closed, the composition is for being blended in hair treating agent, and in the hair conditioner as made from hair treating agent.SAN-EI is public
Cloth discloses a variety of such compositions for being blended in hair treating agent comprising living comprising fatty alcohol and cationic surface
The composition of property agent, for example, in embodiment 100 to 110.SAN-EI announce also disclose by using it is such for blending
The hair conditioner of composition, for example, in embodiment 112 to 118.
In the embodiment 112 to 117 that SAN-EI is announced, composition (102,103,104 and of embodiment of blending will be used for
106) 80 DEG C or higher are heated to, is then mainly mixed with water to prepare hair conditioner.Wherein used for blending
Composition (embodiment 102,103,104 and 106) includes the fluent material of high percentage (for example, 27% the third in embodiment 102
43% glycerol in 47% Albolene, embodiment 104 in glycol, embodiment 103 and 18% Albolene,
And 28% glycerol of embodiment 106) together with fatty alcohol and cationic surfactant.
SAN-EI announce embodiment 118 in, by be used for be blended composition (embodiment 111) be added to be cooled to it is low
In 40 DEG C of lotion, wherein lotion has water and the compositions of additives comprising cationic surfactant and fatty alcohol,
And it is in addition mixed with water to prepare hair conditioner.Composition (embodiment 111) for blending includes ethyl alcohol, cation form
Face activating agent and water more than 80%, and do not include fatty alcohol.
SAN-EI announcement also discloses the preparation of hair conditioner in embodiment 150 to 156.In embodiment 150 to 154
In, the composition (embodiment 123,126,127,130,133 and 134) for being used to be blended is heated above 80 DEG C, and add
Into water, which is also heated to higher than 80 DEG C, and is emulsified and cooled down to prepare hair conditioner.Composition for blending
(embodiment 123,126,127,130,133 and 134) include cationic surfactant and fatty alcohol, and also comprising 15% to
20% liquid oil (in embodiment 123,130 and 133) or 6% to 8% polyoxyethylene ester are (in embodiment 126,127 and
In 134).
Another example can be the U.S. Patent Application Publication No. 2003/223952 from P&G, be related to being used to prepare clear
The method of cleansing composition, this method comprises: (a) be enough to allow surfactant be assigned in fatty alcohol at a temperature of will be fatty
Pure and mild surfactant combines in pre-composition;(b) that mixture is cooled to the chain melt temperature lower than pre-composition is solidifying to be formed
Glue network;(c) gel network is added in detersive surfactant and aqueous carrier to form cleaning compositions.The P&G is public
Cloth discloses embodiment into [0190] in section [0186], coagulates using comprising fatty alcohol and the such of cationic surfactant
Glue network.
In addition, the U.S. Patent Application Publication No. 2016/143827 from Kao disclose at room temperature for solid and its
Middle water content is 10 weight % or smaller composition, and and being dispersed in water solid composite under mild temperature
The hair conditioner composition of preparation.European patent application published number 2394632 from Shiseido is disclosed with extremely low
The hair conditioner composition of water content, and thus hair conditioner composition easily can simply be made and being diluted with water
It makes.
It remains desirable, however, that conditioning composition is to provide at least one of the following:
The greater flexibility of product mix rheological, especially storage modulus (G'), preferably even when use phase
When the active material of same amount such as surfactant and hard fat compounds of group.It is believed that there is different rheologys, especially
It is that the product composition of storage modulus (G') provides different stacking degree, and the product composition with higher stacking degree tends to
Conditioning perception abundant/feel and also tend to be easy to be administered to hair and/or be easily held in palm is provided.
The improved stability of aqueous base composition and product composition, especially when by less amount of active material
When such as surfactant and hard fat compounds of group are in aqueous base composition.
The improved deposition of beneficial agent when in the composition including beneficial agent;
When the stability improved comprising incompatible group of timesharing;
Improved vision/aesthetic appearance.
There is no any prior art to provide all advantages and beneficial effect of the invention.
Summary of the invention
The present invention relates to a kind of methods for preparing product composition, method includes the following steps:
Prepare blend composition, the blend composition include surfactant and hard fat compounds of group,
And the beneficial agent other than the surfactant and the hard fat compounds of group;
Aqueous base composition is prepared separately, which includes aqueous carrier and water-soluble polymer,
Middle base composition is selected from anionic surfactant, two substantially free of detersive surfactant, the detersive surfactant
Property ionic surface active agent, amphoteric surfactant and their combination;
Blend composition and aqueous base composition are mixed, to form the mixing being scattered in aqueous base composition
The discrete particle of compositions.
The invention further relates to a kind of methods for preparing product composition, method includes the following steps:
The discrete particle of blend composition is prepared, the discrete particle includes surfactant and hard fat race
Close object and the beneficial agent other than the surfactant and the hard fat compounds of group;
Aqueous base composition is prepared separately, which includes aqueous carrier and water-soluble polymer,
Middle base composition is selected from anionic surfactant, two substantially free of detersive surfactant, the detersive surfactant
Property ionic surface active agent, amphoteric surfactant and their combination;
The discrete particle is mixed with the aqueous base composition, is dispersed the discrete particle in described aqueous
In base composition.
The inventive process provides the product compositions at least one of the following: product mix rheological
Greater flexibility;The improved stability of product composition;The improved deposition of beneficial agent;And improved vision/aesthetics
Appearance.
By read the following description and the appended claims book, be better understood with these and other features of the invention,
Aspect and advantage.
Specific embodiment
Although this specification using particularly point out and be distinctly claimed claims of the present invention as ending, according to
Letter is better understood the present invention by following explanation.
"comprises/comprising" herein, which refers to, can add not the other steps for influencing final result and other ingredients.The term
Cover term " by ... form " and " substantially by ... form ".
Unless otherwise stated, otherwise all percentages, number and ratio are based on the total weight of the present composition.It is all
These weight for being related to ingredients listed are based on the level of active material, thus do not include be likely to be contained in it is commercially available
Carrier or by-product in material.
Herein, any chemical combination that " mixture " refers to simple combination including material and can be generated by their combination
Object.
As used herein, unless otherwise specified, " molecular weight " refers to weight average molecular weight.Molecular weight uses industrial standard
Method, gel permeation chromatography (" GPC ") measurement.
Blend composition
The blend composition of this paper includes surfactant and hard fat compounds of group.Available mixture herein
Composition also includes beneficial agent.It will be explained in these ingredients later.
In view of having the discrete particle of blend composition in aqueous base composition and in product composition,
And offer at least one of the following is provided, blend composition by based on the weight of product composition preferably about
0.01% to about 70%, more preferably about 0.01% to about 50%, the level of still more preferably about 0.05% to about 30% includes
In product composition: the greater flexibility of product mix rheological;The improved stability of product composition;Beneficial agent
Improved deposition;And improved vision/aesthetic appearance.
When blend composition includes beneficial agent and such beneficial agent is siloxanes and/or fragrance, mixture combination
Object can based on the weight of product composition preferably about 0.1% to about 70%, more preferably about 0.5% to about 50%, also more
Preferably about 1% to about 30%, even more preferably about 2% about 20% level is included in product composition.
When blend composition includes beneficial agent and such beneficial agent is colorant and/or mica, mixture combination
Object can based on the weight of product composition preferably about 0.01% to about 50%, and more preferably about 0.01% to about
30%, still more preferably about 0.01% to about 20%, even more preferably the level of about 0.05% to about 10% is included in product
In composition.
In view of having the discrete particle of blend composition in aqueous base composition and in product composition,
Include simultaneously other ingredients such as beneficial agent, and offer at least one of the following, surfactant and Gao Rong are provided
Point aliphatic compound by based on the weight of blend composition preferably about 10% to about 99.9%, more preferably about 20% to
About 99.9%, still more preferably about 40% to about 99.9%, even more preferably about 60% to about 99.9%, in addition more preferably
The level of about 80% to about 99.9% is present in blend composition, the blend composition with or without it is other at
Point: the greater flexibility of product mix rheological;The improved stability of product composition;The improvement of beneficial agent is sunk
Product;And improved vision/aesthetic appearance.
Other than surfactant and hard fat compounds of group, when blend composition include any liquid, it is all
When such as water-insoluble, water miscibility and water-soluble liquid and water, it is contemplated that in aqueous base composition and in product mix
With the discrete particle of blend composition in object, the level of this class I liquid I is further preferably controlled, so that in blend composition
Total liquid level can be based on the weight of blend composition at most about 92%, at most about 60%, more preferably up to about 50%,
Still more preferably at most about 40%, even more preferably at most about 30%.
When liquid is water-insoluble liquid such as siloxanes, such water-insoluble liquid can be by blend composition
Poidometer is preferably no more than about 90%, at most about 60%, more preferably up to about 50%, still more preferably at most about 40%, very
Level to more preferably up to about 30% is included in blend composition.
When liquid is water miscible liquid such as propylene glycol and glycerol, such water miscible liquid can be by mixture group
Close the poidometer of object preferably no more than about 90%, at most about 60%, more preferably up to about 50%, still more preferably at most about
40%, even more preferably at most about 30% level is included in blend composition.
When liquid is water-soluble liquid such as isopropanol (IPA) and ethyl alcohol, such water-soluble liquid can be by mixture
The poidometer of composition is preferably no more than about 50%, and more preferably up to about 30%, still more preferably at most about 20% level
Included in blend composition.
When blend composition includes water, it is contemplated that have in aqueous base composition and in product composition
The discrete particle of blend composition preferably controls the level of water, so that blend composition includes by blend composition
Water of the poidometer less than about 50%, more preferably less than about 25%, still more preferably less than about 15%, even more preferably less than
About 10%, it is additionally preferred to which ground is less than about 8% water.
Preferably in blend composition, it is contemplated that provide rheology and/or conditioning beneficial effect, surfactant and
Hard fat compounds of group so that the weight ratio of surfactant and hard fat compounds of group in about 1:1 to about 1:
10, more preferably about 1:1 to about 1:4, within the scope of still more preferably about 1:2 to about 1:4 it is horizontal by comprising.
Surfactant for blend composition
Surfactant for blend composition is preferably hydrophobic, and is preferably selected from: cation form
Face activating agent, nonionic surfactant and their mixture;And still more preferably cationic surfactant.This
The preferred cationic surfactant of class is below with title " cationic surfactant " further explanation.
Hard fat compounds of group for blend composition
Hard fat compounds of group for blend composition is below with title " hard fat compounds of group "
Explanation.
Beneficial agent for blend composition
Blend composition also includes the beneficial agent other than surfactant and hard fat compounds of group, this has
Beneficial agent is different from surfactant and hard fat compounds of group.The beneficial agent is also different from may include in blend composition
In aqueous carrier and water.
In view of providing beneficial effect by beneficial agent, and in view of in Aquo-composition and in product composition
Discrete particle with blend composition, beneficial agent can be based on the weight of blend composition preferably about 0.1% to about
90%, more preferably about 0.3% to about 60%, still more preferably about 0.5% to about 40%, even more preferably about 0.5% to
About 30% level is included in blend composition.
Preferably, such beneficial agent be selected from silicone compounds, fragrance, for by different colours from aqueous base composition
Color be added to colorant in discrete particle, incompatible at least one of aqueous base composition ingredient is included in
Incompatible reagent and their mixture.
Such silicone compounds are below with title " silicone compounds " further explanation.
Such fragrance can be any substance, such as fragrance itself and fragrance microcapsule (PMC), and wherein fragrance is by polymerizeing
The encapsulating of beyond the region of objective existence layer.
This based colorant can be any substance, such as pigment and dyestuff.
Such incompatible reagent be, for example, it is selected from the following those:
With high ionic strength and/or high surface charge and tend to lead to solid mineral substance or the change of agglomeration and/or crystallization
Substance is learned, is, for example, mica, salicylic acid and metal pyrithione, such as with or without ionomer coating or dispersion
The zinc pyrithione of body;
The organic oil material to interact with gel network component height, for example,
Hexyl decyl alcohol, isostearyl isostearate ester;
And their mixture.
Depending on the type of beneficial agent, when comprising beneficial agent, product composition can provide at least one of the following:
The improved deposition of beneficial agent;
The stability improved when comprising incompatible reagent;
When comprising colorant to be added to different colours in discrete particle from the color of aqueous base composition, change
Kind vision/aesthetic appearance.
Aqueous base composition
In view of having the discrete particle of blend composition in aqueous base composition and in product composition,
Aqueous base composition can be based on the weight of product composition in right amount to 100%, based on the weight of product composition preferably
About 30% to about 99.9%, more preferably about 50% to about 99.9%, still more preferably about 70% to about 99.9%, it is even more excellent
Selection of land about 80% to about 99.9%, in addition more preferably about 90% to 99.9% level is included in product composition.
Aqueous base composition of the invention includes aqueous carrier.In general, aqueous carrier can be with aqueous basis combination
Object it is appropriate to 100%, based on the weight of aqueous base composition preferably about 40% to about 99%, more preferably about 50% to
About 95%, still more preferably about 70% to about 95%, even more preferably the level of about 80% to about 95% is included in containing water base
In plinth composition.
Water-soluble polymer
Aqueous base composition includes water-soluble polymer.Aqueous base composition may include for example combining by aqueous basis
The poidometer of object about 0.005% to about 10%, preferably about 0.01% to about 5%, more preferably about 0.05% to about 5%, also
More preferably about 0.1% to about 5%, and the even more preferably water-soluble polymer of about 0.2% to about 3%.
Water-soluble polymer can have the solubility in water of the about 0.1g/L to about 500g/L measured at 25 DEG C.Water
Soluble polymer may originate from synthesis or natural, and can be modified via chemical reaction.
In embodiments, water-soluble polymer can have about 5,000g/mol to about 50,000,000g/mol, Huo Zheyue
10,000g/mol to about 10,000,000g/mol, or about 20,000g/mol to about 5,000,000g/mol, and/or about
The weight average molecular weight of 100,000g/mol to about 3,000,000g/mol.
In embodiments, the aqueous base composition with water-soluble polymer can have about 100 lis at 20 DEG C
It moors to about 10,000,000 centipoises, or about 500 centipoises to about 5,000,000 centipoises, and/or about 1000 centipoises are to about
The viscosity of 100,000 centipoises.
Water-soluble polymer can be to be non-ionic, cationic, anion, both sexes, and preferably nonionic
Or it is cationic, especially when include surfactant in discrete particle being non-ionic or cationic.
The non-limiting example of the water-soluble polymer of synthesis can be selected from polyvinyl alcohol, polyvinylpyrrolidone, polycyclic oxygen
Alkane, polyacrylate, caprolactam, polymethacrylates, polymethyl methacrylate, polyacrylamide, polymethyl
Amide, polydimethylacrylamiin, polyethylene glycol monomethacrylate, polyurethane, polycarboxylic acids, polyvinyl acetate, polyester,
Polyamide, polyamine, polyethyleneimine and PEG-240/HDI copolymer BIS-DECYLTETRADECETH-20ETHER.
Other non-limiting examples of synthetic polymer can be selected from anionic monomer, cationic monomer and both sexes list
The copolymer of body and their mixture, including maleic acrylic ester group copolymer, methyl are acrylate-based total
The copolymerization of polymers, the copolymer of the copolymer of methyl vinyl ether and maleic anhydride, the copolymer of vinyl acetate and crotonic acid
Object, the copolymer of the copolymer of vinyl pyrrolidone and vinyl acetate and vinyl pyrrolidone copolymer and oneself
Copolymer, polyquaternium -37, polyquaternium -6 and the polyquaternium -7 of lactams.
The non-limiting example of natural water-soluble copolymer can be selected from karaya gum, bassora gum, gum arabic, acetyl
It mutters, konjacmannan, acacia gum, Indian gum, whey protein isolate, soybean protein isolate, guar gum, locust bean
Jiao, Wen Quince seed glue, psyllium seed gum, carrageenan, alginates, agar, fruit extract (pectin), xanthan gum, gellan gum, branch
Starch, hyaluronic acid, chondroitin sulfate and glucan, casein, gelatin, keratin, keratin hydrolyzate, sulfonic acid keratin,
Albumin, collagen, glutelin, glucagon, seitan, zein, shellac and their mixture.
The non-limiting example of modified natural water-soluble polymer can be selected from: (1) cellulose derivative, including hydroxypropyl first
Base cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, methylcellulose, hydroxypropyl cellulose, ethyl cellulose, carboxymethyl
Cellulose, Cellacefate, nitrocellulose, cellulose ether, cellulose esters;And (2) guar derivative,
Including hydroxypropyl guar gum.Suitable hydroxypropyl methyl cellulose may include can be from Dow Chemical Company
Those of (Midland, MI) acquisition.
Wherein, in fact it is highly preferred that be polyquaternium -37 and PEG-240/HDI copolymer BIS-DECYLTETRADECETH-
20ETHER。
Water mobility
Preferably, aqueous base composition has about 50ms to about 2350ms, and more preferably about 70ms is to about
The water mobility value (T2 (ms)) of 2300ms, still more preferably about 90ms to about 2250ms.For example, 100% pure water has
The water mobility of 2388ms, and 1.5% aqueous solution of ADEKA NOL GT730 has the water mobility of 2214ms.
By the CPMG method (cp_mb described in software) analyzed for pulse NMR, in more detail, by using
Minispec mq20 NMR analyzer (Bruker) obtains water mobility value by measurement spin spin relaxation time.In allusion quotation
In the measurement of type, about 5 grams of samples (accurate weight of record sample) are sealed in the NMR pipe that diameter is 18mm.It is managed by NMR
Start to measure within 1 minute after in inserting instrument.These measurements are to carry out under the following conditions:
90 ° of -180 ° of pulses separate (tau): 0.04ms-1.6ms;
The circulation delay time: 25s;
Cumulative frequency: 8 times;
Measurement temperature: 25 DEG C.
Spin spin relaxation time is calculated by " overlapping " the method fitting of exponential decay curve in minispec software
(T2).Peak position is identified by the position of summit.
Substantially free of detersive surfactant
Aqueous base composition of the invention is substantially free of detersive surfactant.The detersive surfactant of this paper is
It is selected from the following those: anionic surfactant, zwitterionic surfactant, amphoteric surfactant and they
Combination.
In the present invention, " composition is substantially free of detersive surfactant " refers to: aqueous base composition is free of and is gone
Dirty surfactant;Alternatively, if aqueous base composition includes detersive surfactant, such detersive surfactant
It is horizontal very low.In the present invention, if comprising the total level of such detersive surfactant is by aqueous base composition
Poidometer is preferably 0.1% or less, and more preferably 0.05% or less, still more preferably 0.01% or less.Most preferably
The total level on ground, such detersive surfactant is calculated as 0% by the weight of aqueous base composition.
Product composition (discrete particle comprising blend composition and aqueous base composition) can also be substantially free of
Detersive surfactant.
Surfactant in aqueous base composition
Aqueous base composition may include surfactant, which is preferably hydrophobic, and is selected from: sun
Ionic surface active agent, nonionic surfactant and their mixture;And preferably cationic surfactant.
Such preferred cationic surfactant is below with title " cationic surfactant " further explanation.Surfactant
Can based on the weight of aqueous base composition preferably about 0.1% to about 10%, more preferably about 0.3% to about 8%, also more
Preferably about 0.5% to about 5%, even more preferably the level of about 0.7% to about 4% is included in aqueous base composition.
Hard fat compounds of group in aqueous base composition
Aqueous base composition may include hard fat compounds of group.Hard fat compounds of group can be by containing water base
The poidometer of plinth composition preferably about 0.5% to about 15%, more preferably about 1.0% to about 10%, still more preferably about
1.5% to about 8.0%, even more preferably about 2.0% to about 6.0%, the other more preferably water of about 2.5% to about 6.0%
It is flat to be included in aqueous base composition.
Hard fat compounds of group is illustrated below with title " hard fat compounds of group ".
Beneficial agent for aqueous base composition
Aqueous base composition also may include the beneficial agent other than surfactant and hard fat compounds of group,
The beneficial agent is different from surfactant and hard fat compounds of group.The beneficial agent is also different from aqueous carrier and water.
In view of providing beneficial effect by beneficial agent, and in view of not damaging from aqueous base composition, especially
The beneficial effect of surfactant and hard fat compounds of group, beneficial agent can be excellent based on the weight of aqueous base composition
Selection of land about 0.05% to about 60%, more preferably about 0.1% to about 30%, still more preferably about 0.1% to about 20%, even more
The level of preferably about 0.1% to about 10% is included in aqueous base composition.
In view of providing beneficial effect by beneficial agent, and in view of not damaging from aqueous base composition, especially
The beneficial effect of surfactant and hard fat compounds of group, beneficial agent can be comprised in aqueous base composition, make
Beneficial agent can based on the weight of product composition preferably about 0.05% to about 30%, more preferably about 0.1% to about
15%, still more preferably about 0.1% to about 10%, even more preferably the level of about 0.1% to about 7% is included in product mix
In object.
Preferably, for such beneficial agent in aqueous base composition be selected from silicone compounds, fragrance, be included in
In blend composition and/or at least one of the discrete particle incompatible incompatible reagent of ingredient and their mixing
Object.It is highly preferred that be incompatible reagent for such beneficial agent in aqueous base composition, the incompatible reagent be included in
In blend composition and/or at least one of discrete particle ingredient is incompatible.
Such silicone compounds are below with title " silicone compounds " further explanation.
Such fragrance can be any substance, such as fragrance itself and fragrance microcapsule (PMC), and wherein fragrance is by polymerizeing
The encapsulating of beyond the region of objective existence layer.
Such incompatible reagent be, for example, it is selected from the following those:
With high ionic strength and/or high surface charge and tend to lead to solid mineral substance or the change of agglomeration and/or crystallization
Substance is learned, is, for example, mica and metal pyrithione, such as pyrrole with or without ionomer coating or dispersion
Pyridine thioketones zinc;
The organic oil material to interact with gel network component height, for example, hexyl decyl alcohol, isostearyl isostearate
Ester;
And their mixture.
Depending on the type of beneficial agent, when comprising beneficial agent, product composition can provide at least one of the following:
The improved deposition of beneficial agent;
The stability improved when comprising incompatible reagent.
Discrete particle
Product composition includes the discrete particle of blend composition.The discrete particle of this paper is to be scattered in aqueous base set
It those of closes in object and can visually, such as be observed in final products composition with discrete particle form by microscope
It arrives, however, those do not show Maltese cross label when being measured by polarization microscope.This, which refers to, can be used for this paper's
Discrete particle is not that typically in lotion (such as comprising the aqueous of surfactant, hard fat compounds of group and aqueous carrier
Base composition) in the vesica observed.In general, surfactant, hard fat compounds of group and aqueous carrier shape
At lotion, preferably gel-type vehicle.In such lotion and gel-type vehicle, these components are usually formed stratiform vesica and/or layer
Shape piece.Such stratiform vesica can be observed by microscope with discrete particle form, however, when being measured by polarizing microscope
Maltese cross label is shown.
In view of provide at least one of the following, discrete particle by based on the weight of product composition preferably about
0.1% to about 70%, more preferably about 0.1% to about 50%, still more preferably the level of about 0.1% to about 30%, which is included in, produces
In product composition: the greater flexibility of product mix rheological;The improved stability of product composition;Beneficial agent changes
Kind deposition;And improved vision/aesthetic appearance.
Discrete particle is preferably swollen in product composition, is swollen more preferably by aqueous carrier, still more preferably
By water-swellable.Discrete particle can be by aqueous carrier from aqueous base composition and/or water in aqueous base composition
Middle swelling.Alternatively or simultaneously, discrete particle is swellable, then mixes it with aqueous base composition, such as by mixing
When compositions prepare discrete particle or later, disperse discrete particle is come as solvent by using aqueous carrier and/or water.When
When calculating the amount of component, it is believed that such solvent is the component of aqueous base composition.
It is believed that the swelling of discrete particle is saturation in about 3 days and at most 1 week time of longest, granularity is not considered, and
And do not consider internal whether comprising beneficial agent.Also, it is believed that this thing happens, then the diffusion of discrete particle and/or collapse
Contracting will occur within 1 week and longest is completed within 3 weeks.It is also believed that the physical characteristic and beneficial effect of discrete particle can be molten
It is swollen, spread and/or change during collapsing, but will stabilize and will not change after 3 weeks.Therefore, can be used for this paper from
Scattered seed be present in composition preferably up to 1 month or longer, more preferably 3 months or longer, still more preferably 6 months or
It is longer, in addition more preferably up to 12 months or longer, even more preferably up to 24 months or longer.
The discrete particle of swelling preferably has about 1 micron to about 2000 microns, more preferably about 10 microns to about 1000
Micron, still more preferably about 50 microns to about 500 microns of granularity.The discrete particle of such swelling can also by microscope with from
Scattered seed form is observed, however, not showing Maltese cross label when measuring by polarization microscope.
The discrete particle of this paper and the discrete particle of swelling can be any shape, such as spherical, rectangle or diamond shape.
Before swelling, it is preferable that discrete particle is solid.
Before swelling, discrete particle preferably includes 100% blend composition, that is, by blend composition group
At.When discrete particle includes water before swelling, the level of water is controlled preferably before swelling, so that discrete particle is being swollen
Before comprising based on the weight of discrete particle be less than about 50% water, more preferably less than about 25%, still more preferably less than about
15%, even more preferably less than about 10%, it is additionally preferred to which ground is less than about 8% water.
Before swelling, it is contemplated that there is blend composition in aqueous base composition and in product composition
Discrete particle, surfactant and hard fat compounds of group are by based on the weight of discrete particle preferably about 10% to about
100%, more preferably about 20% to about 100%, still more preferably about 40% to about 100%, even more preferably about 60% to
About 100%, in addition the level of more preferably about 80% to about 100% is present in discrete particle, which has or not
With other ingredients.
Before and after swelling, discrete particle is preferably not oil-in-water emulsion or water-in-oil-in-water compositions, more preferably
Ground is not any lotion, including water-in-oil emulsion and oil in water in oil emulsion.
The discrete particle of this paper is different from the particle by such as polymer-coated or encapsulating.
The discrete particle that can be used for this paper is different from swellable silicone elastomer and swellable thickening polymer.It is preferred that
Ground, discrete particle and blend composition are substantially free of such swellable silicone elastomer and swellable thickening polymer.
In the present invention, " discrete particle and blend composition are poly- substantially free of swellable silicone elastomer and swellable thickening
Close object " refer to: discrete particle and blend composition are without swellable silicone elastomer and swellable thickening polymer;Or
Person, it is such if discrete particle and blend composition include swellable silicone elastomer and swellable thickening polymer
The level of swellable silicone elastomer and swellable thickening polymer is very low.In the present invention, if comprising, it is such can
The total level of silicone elastomer and swellable thickening polymer is swollen based on the weight of discrete particle or by blend composition
Poidometer be preferably 0.1% or less, more preferably 0.05% or less, be still more preferably 0.01% or less.
Most preferably, the total level of such swellable silicone elastomer and swellable thickening polymer based on the weight of discrete particle or
0% is calculated as by the weight of blend composition.
2nd discrete particle
In addition to above comprising the of the invention discrete of the mixture containing surfactant, the pure and mild beneficial agent of hard fat
Except particle, product composition of the invention also may include the 2nd discrete particle.The 2nd discrete particle that can be used for this paper includes not
Mixture including beneficial agent includes the mixture of surfactant and hard fat compounds of group.In addition to comprising beneficial
Except agent, the component and characteristic of the 2nd discrete particle are identical as those of described in discrete particle of the invention above.
Product composition
Product composition includes discrete particle and aqueous base composition, is preferably combined by discrete particle and aqueous basis
Object composition.Product composition of the invention can be any substance, and be preferably chosen from hair care product composition, body shield
Manage product composition, face protection product composition and their mixture, more preferably hair care product composition.
In hair care composition, it is even more preferred that hair care composition, wherein being included in discrete particle and Aquo-composition
In surfactant be cationic surfactant.
Product form
Product composition of the invention can be rinse-off products or leave product form, and can be configured to a variety of productions
Product form, including but not limited to creams, gel, lotion, mousse and spray.Product composition of the invention is particularly suitable for hair
Conditioner, especially rinse-off hair conditioner.
When being used as rinse off conditioner, product composition is preferably used by following steps:
(i) after shampoo hair, a effective amount of conditioner composition is applied to be used for conditioning hair to hair;With
And
(ii) hair is then rinsed.
Herein, effective quantity is the every 10g hair of for example, about 0.1ml to about 2ml, and preferably about 0.2ml is every to about 1.5ml
10g hair.
Cationic surfactant
Can be used for this paper cationic surfactant can for a kind of cationic surfactant or two or more
The mixture of cationic surfactant.Preferably, cationic surfactant is selected from: single-long-chain alkyl quaternized ammonium salt;It is single
The combination of chain alkyl quaternized ammonium salt and two chain alkyl quaternized ammonium salts;Single-long-chain alkyl amine;Single-long-chain alkyl amine and two
The combination of chain alkyl quaternized ammonium salt.
Single-long-chain alkyl quaternized ammonium salt
The single-long-chain alkyl quaternized ammonium salt that can be used for this paper is that have those of long alkyl chain, long alkyl chain tool
There are 12 to 30 carbon atoms, preferably 16 to 24 carbon atoms, more preferably C18-22 alkyl group.It is connected to its complementary basis of nitrogen
Alkyl group of the group independently selected from 1 to about 4 carbon atom, or the alkoxy base at most about 4 carbon atoms, polyoxy
Change alkylidene group, alkyl amido group, hydroxyalkyl group, aryl group or kiki fang alkyl group.
The single-long-chain alkyl quaternized ammonium salt that can be used for this paper is with those of formula (I):
Wherein R75、R76、R77And R78One of be selected from 12 to 30 carbon atoms alkyl group, or have at most about
Aromatic group, alkoxy base, polyalkylene oxide group, alkyl amido group, the hydroxyalkyl group, virtue of 30 carbon atoms
Base group or kiki fang alkyl group;Wherein R75、R76、R77And R78In rest part independently selected from 1 to about 4 carbon atom
Alkyl group, or the alkoxy at most about 4 carbon atoms, polyoxyalkylene, alkyl amido, hydroxyalkyl, aryl
Or kiki fang alkyl group;And X-For salt forming anion, such as selected from halogen (such as chloride ion, bromide ion), acetate, lemon
Acid group, lactate, ethyl alcohol acid group, phosphate radical, nitrate anion, sulfonate radical, sulfate radical, alkyl sulfate and alkyl azochlorosulfonate group
Those.Other than carbon atom and hydrogen atom, alkyl group also may include ehter bond and/or ester bond and other groups such as ammonia
Base group.The alkyl group of longer chain, such as with those of about 12 or more carbon can be saturated or unsaturated.It is excellent
Selection of land, R75、R76、R77And R78One of be selected from 12 to 30 carbon atoms, more preferably 16 to 24 carbon atoms, even more preferably from
18 to 22, ground carbon atom, the even more preferably alkyl group of 22 carbon atoms;R75、R76、R77And R78In rest part it is only
On the spot it is selected from CH3、C2H5、C2H4OH and their mixture;And X is selected from Cl, Br, CH3OSO3、C2H5OSO3And it
Mixture.
The non-limiting example of such single-long-chain alkyl quaternized ammonium salt cationic surfactant includes: docosyl
Leptodactyline;Stearyl trimethyl ammonium salt;Cetyltrimethylammonium ammonium salt;And hydrogenated tallow alkyl leptodactyline.
Two chain alkyl quaternized ammonium salts
When in use, in view of rheological stability and conditioning beneficial effect, two chain alkyl quaternized ammonium salts preferably with
Single-long-chain alkyl quaternized ammonium salt or single-long-chain alkyl amine salt are with 1:1 to 1:5, more preferably 1:1.2 to 1:5, still more preferably
1:1.5 the weight ratio to 1:4 combines.
The two chain alkyl quaternized ammonium salts that can be used for this paper are with 12 to 30 carbon atoms, more preferably 16 to 24
Carbon atom, those of two long alkyl chains of still more preferably 18 to 22 carbon atoms.It can be used for the such two long alkanes of this paper
Base quaternized ammonium salt is with those of formula (I):
Wherein R71、R72、R73And R74In the two be selected from have 12 to 30 carbon atoms, preferably 16 to 24 carbon atoms,
The aliphatic group of more preferably 18 to 22 carbon atoms, or the aromatic group at most about 30 carbon atoms, alkoxy base,
Polyalkylene oxide group, alkyl amido group, hydroxyalkyl group, aryl group or kiki fang alkyl group;R71、R72、R73With
R74In rest part independently selected from have 1 to about 8 carbon atom, the aliphatic group of preferably 1 to 3 carbon atom, or tool
There are aromatic group, alkoxy base, polyalkylene oxide group, the alkyl amido group, hydroxyalkyl of at most about 8 carbon atoms
Group, aryl group or kiki fang alkyl group;And X- is salt forming anion, is selected from: halogen ion such as chloride ion and bromine from
Son, C1-C4 alkyl sulfate such as methylsulfate and ethyl ester sulfate radical and their mixture.In addition to carbon atom and hydrogen
Other than atom, aliphatic group can also contain ehter bond and other groups such as amino group.The aliphatic group of more long-chain, such as with
Those of about 16 or more carbon can be saturated or unsaturated.Preferably, R71、R72、R73And R74In the two be selected from 12 to
30 carbon atoms, preferably 16 to 24 carbon atoms, the alkyl group of more preferably 18 to 22 carbon atoms;And R71、R72、
R73And R74In rest part independently selected from CH3、C2H5、C2H4OH、CH2C6H5And their mixture.
Such preferred two chain alkyls cationic surfactant includes such as dialkyl group (14-18) dimethylammonium chloride
Ammonium, two tallow alkyl alkyl dimethyl ammonium chlorides, dihydrogenated tallow alkyl dimethyl ammonium chloride, VARISOFT TA100 and two
Cetyl dimethyl ammonium chloride.
Single-long-chain alkyl acylamino- amine salt
Single-long-chain alkyl amine is also suitable for cationic surfactant.Armeen, secondary aliphatic amine and aliphatic
Tertiary amine is available.Especially useful is the tertiary amidoamines of the alkyl group with about 12 to about 22 carbon.Illustrative uncle
Amidoamines include: stearamido propyl, stearamidopropyl diethylamide, stearoyl amino-ethyl diethyl
Base amine, stearoyl amino ethyldimethyl amine, palmitoylamino propyl-dimethyl amine, palmitoylamino propyl diethylamide, palm fibre
Palmitic acid acylamino- ethyl diethylamide, palmitoylamino ethyldimethyl amine, docosane cocoamidopropyl dimethyl amine, 22
Alkyl amido propyl diethylamide, docosane acylamino- ethyl diethylamide, docosane acylamino- ethyldimethyl amine, two
Ten alkyl amido propyl-dimethyl amines, eicosane cocamidopropyl diethylamide, eicosane acylamino- ethyl diethylamide, 20
Alkyl amido ethyldimethyl amine, diethylamino ethyl stearamide.Available amine is disclosed in Nachtigal etc. in the present invention
In the United States Patent (USP) 4,275,055 of people.These amine can also be used in combination with following acid, such as l- glutamic acid, lactic acid, hydrochloric acid, apple
Acid, succinic acid, acetic acid, fumaric acid, tartaric acid, citric acid, Pidolidone hydrochloride, maleic acid and their mixture;More
Preferably Pidolidone, lactic acid, citric acid.Amine herein is preferably partly neutralized with any one of these acid, wherein
The molar ratio of amine and acid is about 1:0.3 to about 1:2, more preferably about 1:0.4 to about 1:1.
Hard fat compounds of group
In view of the stability of lotion especially gel-type vehicle, the hard fat compounds of group that can be used for this paper has 25
DEG C or it is higher, preferably 40 DEG C or higher, more preferably 45 DEG C or higher, still more preferably 50 DEG C or higher fusing point.Consider
To being easily manufactured and be easier to emulsify, it is preferable that such fusing point is at most about 90 DEG C, and more preferably up to about 80 DEG C, also more
Preferably no more than about 70 DEG C, even more preferably at most about 65 DEG C.In the present invention, hard fat compounds of group can be single
The blend or form of mixtures of compound form or at least two hard fat compounds of group use.When with such blending
Object or form of mixtures are in use, above-mentioned fusing point refers to the fusing point of blend or mixture.
The hard fat compounds of group that can be used for this paper is selected from fatty alcohol, fatty acid, fatty alcohol derivative, fatty acid and spreads out
Biology and their mixture.It will be understood by those of skill in the art that the chemical combination disclosed in this part of specification
Object may belong to more than one classification in some cases, such as certain fatty alcohol derivatives can be further cataloged as being fatty acid and derive
Object.However, the classification provided is not intended to limit specific compound, but carried out for the ease of classifying and naming
's.In addition, it will be appreciated by those skilled in the art that being had according to the length and position of the number and location of double bond and branch
Certain compounds of carbon atom needed for certain, which may have, is lower than in the present invention fusing point of preferred fusing point above.It is not intended to this
Class low-melting compound includes in the portion.The non-limiting example of high melting compound is found in " International
Cosmetic Ingredient Dictionary ", the 5th edition, 1993 and " CTFA Cosmetic Ingredient
Handbook ", the second edition, in 1992.
In a variety of hard fat compounds of group, preferably fatty alcohol is used in composition of the invention.It can be used for
The fatty alcohol of this paper is that have about 14 to about 30 carbon atoms, those of preferably about 16 to about 22 carbon atoms.These fat
Alcohol is saturation and can be straight chain alcohol or branched-chain alcoho.
Preferred fatty alcohol includes for example, cetanol (fusing point with about 56oC), stearyl alcohol are (with about 58-59oC
Fusing point), docosanol (fusing point with about 71oC) and their mixture.These known compounds have above-mentioned fusing point.
However, when serving, they usually have lower fusing point, because the product of such supply is usually to have wherein alkyl backbones
For the mixture for the fatty alcohol that the alkyl chain length of cetyl, stearyl or docosyl group is distributed.
In the present invention, preferred fatty alcohol is the mixture of cetanol and stearyl alcohol.
In general, in the mixture, the weight ratio of cetanol and stearyl alcohol is preferably about 1:9 to 9:1, more preferably about 1:
4 to about 4:1, still more preferably about 1:2.3 are to about 1.5:1
Aqueous carrier
The level and type of aqueous carrier are selected according to feature needed for other of the compatibility and product with other components.
Carrier for use in the present invention includes the aqueous solution of water and lower alkyl alcohol.The lower alkyl alcohol that can be used for this paper is
Monohydric alcohol with 1 to 6 carbon, more preferably ethyl alcohol and isopropanol.
Preferably, aqueous carrier is substantially water.Deionized water is preferably used.According to the required feature of product, may be used also
Use the water from natural source comprising mineral cation.
Silicone compounds
Preferably, when including in aqueous base composition, silicone compounds have in aqueous base composition
About 10nm to about 100 microns, more preferably about 0.1 micron to about 100 microns, still more preferably about 1 micron to about 50 microns
Average particle size.
As single compound, the blend as at least two silicone compounds or mixture or as at least
The blend or mixture of a kind of silicone compounds and at least one solvent, the silicone compounds that can be used for this paper have
The viscosity of preferably about 1,000mPas to about 2,000,000mPas at 25 DEG C.
Viscosity can be measured by means of glass capillary tube viscometer, such as the Dow Corning on July 20th, 1970
Described in Corporate Test Method CTM0004.Suitable siloxanes fluids include polyalkylsiloxane, poly- aryl silicon
Oxygen alkane, Polyalkylaryl siloxane, polyether siloxane copolymer, amino replace siloxanes, quaternized siloxane and they
Mixture.Other nonvolatile silicone compounds with conditioning characteristic also can be used.
In some embodiments it is preferred that the siloxanes that ground uses amino to replace.Preferred amino silicone includes for example
Meet those of logical formula (I):
(R1)aG3-a-Si-(-OSiG2)n-(-OSiGb(R1)2-b)m-O-SiG3-a(R1)a
Wherein G is hydrogen, phenyl, hydroxyl or C1-C8Alkyl, preferably methyl;A is the integer of 0 or the value with 1 to 3, excellent
Selection of land 1;B is 0,1 or 2, preferably 1;The number that n is 0 to 1,999;The integer that m is 0 to 1,999;The sum of n and m are 1 to 2,000
Number;A and m is not 0;R1To meet general formula CqH2qThe univalent perssad of L, wherein q is the integer of the value with 2 to 8, and L
Selected from following group :-N (R2)CH2-CH2-N(R2)2;-N(R2)2;-N(R2)3Aˉ;-N(R2)CH2-CH2-NR2H2Aˉ;Wherein R2For
Hydrogen, phenyl, benzyl or saturated hydrocarbons group, preferably about C1To about C20Alkyl group;AˉFor halogen ion.
Highly preferred amino silicone is wherein m=0, a=1, q=3 corresponding to those of formula (I), G=methyl, n
Preferably about 1500 to about 1700, more preferably about 1600;And L is-N (CH3)2Or-NH2, more preferably-NH2.It is another
Kind highly preferred amino silicone is the wherein m=0 corresponding to those of formula (I), and a=1, q=3, G=methyl, n is preferably
It is about 400 to about 600, more preferably about 500;And L is-N (CH3)2Or-NH2, more preferably-NH2.It is such highly preferred
Amino silicone is referred to alternatively as terminal aminosilicone, because the one or both ends of siloxane chain are blocked by nitrogen-containing group.
When mixing above-mentioned amino silicone in composition, amino silicone can be mixed with having the solvent compared with low viscosity
It closes.For example, such solvent includes polarity or nonpolar, volatility or non-volatile oil.For example, it is such oil include silicone oil,
Hydrocarbon and ester.In such multi-solvents, preferably it is selected from the following those: nonpolar volatile hydrocarbon, volatile cyclic silicon oxygen
Alkane, non-volatile, linear silicones and their mixture.The non-volatile, linear silicones that can be used for this paper are that have
About 1 centistoke to about 20,000 centistokes at 25 DEG C, those of the viscosity of preferably about 20 centistokes to about 10,000 centistokes.Preferred
Solvent in, it is contemplated that reduce the viscosity of amino silicone and the hair conditioning benefit for providing improvement such as subtract in drying hair
Few friction, in fact it is highly preferred that be non-polar volatile hydrocarbon, especially nonpolar volatile isoparaffin hydrocarbons.Such mixture has excellent
Selection of land about 1,000mPas to about 100,000mPas, more preferably about 5,000mPas are viscous to about 50,000mPas's
Degree.
The silicone compounds that other suitable alkyl aminos replace include the alkane with the side group as siloxane main chain
Those of base amino-substituent.Referred to as those of " amino-terminated dimethyl silicone polymer " is highly preferred.It can be used for this
The commercially available amino-terminated dimethyl silicone polymer of text includes the BY16-872 for example purchased from Dow Corning.
Siloxane polymer comprising quaternary group
The silicone compounds that can be used for this paper include siloxanes for example comprising the quaternary group containing end ester group
Polymer, the siloxane polymer have the at most viscosity of 100,000mPas and the D block length greater than 200D unit.No
It is bound by theory, which provides the friction of improved conditioning beneficial effect such as smooth feeling, reduction
And damaged hair is prevented, while eliminating the needs to silicone blend.
From structure, siloxane polymer is polyorganosiloxane compounds, and it includes one or more quaternary ammonium groups
Group, at least one include greater than the siloxane blocks of 200 siloxane units, at least one polyalkylene oxide structural unit and extremely
A few end ester group.In one or more embodiments, siloxane blocks may include 300 to 500 siloxane units.
Siloxane polymer by based on the weight of composition about 0.05% to about 15%, preferably about 0.1% to about 10%,
More preferably about 0.15% to about 5%, and even more preferably the amount of about 0.2% to about 4% exists.
In a preferred embodiment, polyorganosiloxane compounds have general formula (Ia) and (Ib):
M—Y—[—(N+R2—T—N+R2)—Y—]m—[—(NR2—A—E—A’—NR2)—Y—]k—M
(Ia)
M—Y—[—(N+R2—T—N+R2)—Y—]m—[—(N+R2 2—A—E—A’—N+R2 2)—Y—]k—M
(Ib)
Wherein:
M > 0, preferably 0.01 to 100, more preferably 0.1 to 100, even more preferably 1 to 100, specifically 1 to 50,
More specifically 1 to 20, or even more specifically 1 to 10,
K is 0 or from > 0 to 50, or preferably 1 to 20, or even more preferably 1 to 10 average value.
M indicates end group, and it includes end ester groups selected from the following
-OC(O)-Z
-OS(O)2-Z
-OS(O2)O-Z
-OP(O)(O-Z)OH
-OP(O)(O-Z)2
Wherein Z is selected from at most 40 carbon atoms, optionally comprising one or more heteroatomic monovalence organic residues.
A and A ' is respectively independently from each other singly-bound or has at most 10 carbon atoms and one or more heteroatomic two
Valence organic group, and
E is the polyalkylene oxygen groups with following general formula:
—[CH2CH2O]q—[CH2CH(CH3)O]r—[CH2CH(C2H5)O]s—
Wherein q=0 to 200, r=0 to 200, s=0 to 200, and q+r+s=1 to 600.
R2Selected from hydrogen or R,
R is selected from at most 22 carbon atoms and the optional heteroatomic monovalent organic group of one or more, and its
Free valency at middle nitrogen-atoms is integrated to carbon atom,
Y is the group with following formula:
- K-S-K-and-A-E-A'-or-A'-E-A-,
WhereinWherein R1=C1-C22Alkyl, C1-C22Fluoro-alkyl
Or aryl;N=200 to 1000, and if there are several S groups in polyorganosiloxane compounds, these can phase
It is same or different.
K is the C of divalent or trivalent straight chain, ring-type and/or branch2-C40Hydrocarbon residue, be optionally inserted into-O-,-
NH-, trivalent N ,-NR1- ,-C (O)-,-C (S)-, and optionally replaced by-OH, wherein R1As defined above,
T, which is selected from, has at most 20 carbon atoms and one or more heteroatomic bivalent organic groups.
Residue K can be same or different to each other.In-K-S-K-part, residue K is integrated to residue S via C-Si- key
Silicon atom.
Since there may be amine groups (- (NR in polyorganosiloxane compounds2—A—E—A’—NR2) -), therefore
It can have the protonation ammonium group obtained by this class amine groups by organic acid or inorganic acid protonation.Such compound is sometimes
The referred to as acid-addition salts of polyorganosiloxane compounds.
In a preferred embodiment, the molar ratio of quaternary ammonium group b) and end ester group c) is less than 100:20, very
To even more preferably less than 100:30, and more preferably less than 100:50.The ratio can pass through13C-NMR is determined.
In another embodiment, constituent polyorganosiloxane composition may include:
A) at least one polyorganosiloxane compounds, it includes a) at least one polyorganosiloxane group, b) at least
One quaternary ammonium group, c) at least one end ester group and d) at least one polyalkylene oxygen groups (as previously defined),
B) at least one polyorganosiloxane compounds, it includes at least one end ester groups different from compound A)
Group.
In the definition of component A), it can be referred in the description of polyorganosiloxane compounds of the invention.Gather organic
Silicone compounds B) with polyorganosiloxane compounds A) difference be preferably its do not include quaternary ammonium group.It is preferred that
Polyorganosiloxane compounds B) derive from simple function organic acid (specifically carboxylic acid) and the poly-organosilicon comprising di-epoxide
The reaction of oxygen alkane.
In constituent polyorganosiloxane composition, compound A) with the weight ratio of compound B) it is preferably less than 90:10.Or it changes
Word says, compound B) content be at least 10 weight %.In compound A) constituent polyorganosiloxane composition another is excellent
In the embodiment of choosing, the molar ratio of quaternary ammonium group b) and end ester group c) are less than 100:10, even more preferably less than
100:15, and more preferably less than 100:20.
Siloxane polymer has in 20 DEG C and 0.1s-1Shear rate under (board-to-board system, board diameter 40mm, relief width
Spend 0.5mm) it is less than the viscosity of 100,000mPas (100Pas).In another embodiment, pure siloxane polymer
Viscosity can be in 500mPas to 100,000mPas, or preferably 500mPas to 70,000mPas, or more preferably
500mPas to 50,000mPas, or even more preferably in the range of 500mPas to 20,000mPas.Another
In a embodiment, the viscosity of straight polymer can be 20 DEG C and 0.1s-1Shear rate under the 500mPas to 10 that measures,
In the range of 000mPas, or preferably 500mPas to 5000mPas.
Other than siloxane polymer listed above, following preferred composition is hereafter additionally provided.For example, having
Have in the polyalkylene oxygen groups E of following general formula:
—[CH2CH2O]q—[CH2CH(CH3)O]r—[CH2CH(C2H5)O]s—
Wherein subscript q, r and s can such as give a definition:
Q=0 to 200, or preferably 0 to 100, or more preferably 0 to 50, or even more preferably 0 to 20,
R=0 to 200, or preferably 0 to 100, or more preferably 0 to 50, or even more preferably 0 to 20,
S=0 to 200, or preferably 0 to 100, or more preferably 0 to 50, or even more preferably 0 to 20, and
Q+r+s=1 to 600, or preferably 1 to 100, or more preferably 1 to 50, or even more preferably 1 to 40.
For the polysiloxane structural unit with following general formula S:
R1=C1-C22Alkyl, C1-C22Fluoro-alkyl or aryl;N=200 to 1000, or preferably 300 to 500, K
(in group-K-S-K -) is preferably the C of divalent or trivalent straight chain, ring-type or branch2-C20Hydrocarbon residue, optionally
Inserted with-O-,-NH-, trivalent N ,-NR1- ,-C (O)-,-C (S)-, and optionally replaced by-OH.
In specific embodiments, R1For C1-C18Alkyl, C1-C18Fluoro-alkyl and aryl.In addition, R1Preferably
C1-C18Alkyl, C1-C6Fluoro-alkyl and aryl.In addition, R1More preferably C1-C6Alkyl, C1-C6Fluoro-alkyl, it is even more excellent
Selection of land C1-C4Fluoro-alkyl and phenyl.Most preferably, R1For methyl, ethyl, trifluoro propyl and phenyl.
As used herein, term " C1-C22Alkyl " refers to that aliphatic hydrocarbon group has 1 to 22 carbon atom, can be straight chain
Or branch.Methyl, ethyl, propyl, normal-butyl, amyl, hexyl, heptyl, nonyl, decyl, undecyl, isopropyl, new penta
Base and 1,2,3- trimethyl part are used as example.
In addition, as used herein, term " C1-C22Fluoro-alkyl " refers to the aliphatic hydrocarbonylation with 1 to 22 carbon atom
Close object, can for linear chain or branched chain and be substituted at least one fluorine atom.One methyl fluoride, a fluoro ethyl, 1,1,1- trifluoro second
Base, perfluoro-ethyl, 1,1,1- trifluoro propyl, 1,2,2- triRuorobutyl are suitable example.
In addition, term " aryl " refer to it is unsubstituted or by OH, F, Cl, CF3、C1-C6Alkyl, C1-C6Alkoxy, C3-
C7Naphthenic base, C2-C6Alkenyl or phenyl replace one or many phenyl.Aryl also can refer to naphthalene.
For the embodiment of polysiloxane, the positive charge derived from one or more ammoniums is by following substance
With: inorganic anion such as chloride ion, bromide ion, hydrogen sulfate ion, sulfate ion or organic anion are such as derived from
The carboxylic acid ion (such as acetate, propionate, sad root) of C1-C30 carboxylic acid, is especially derived from the carboxylic of C10-C18 carboxylic acid
Acid ion (for example, capric acid root, dodecane acid group, tetradecane acid group, hexadecane acid group, octadecane acid group and oleic acid root), alkane
Base polyether carboxylic acid's root, alkyl azochlorosulfonate, arylsulphonate, alkyl aryl sulphonic acid root, alkyl sulfate, alkyl, polyether sulfate radical,
Phosphate radical derived from phosphoric acid one alkyl/aryl ester and di(2-ethylhexyl)phosphate alkyl/aryl ester.The property of polyorganosiloxane compounds is outstanding
It can be modified based on the selection of acid used.
Quaternary ammonium group usually by make in the presence of monocarboxylic acid and bifunctional saturated dihalide based compound two tertiary amines with
Alkylating reagent is reacted and is generated, which is specifically selected from dicyclic oxide (being also known as di-epoxide sometimes).
In a preferred embodiment, polyorganosiloxane compounds have general formula (Ia) and (Ib):
M—Y—[—(N+R2—T—N+R2)—Y—]m—[—(NR2—A—E—A’—NR2)—Y—]k—M
(Ia)
M—Y—[—(N+R2—T—N+R2)—Y—]m—[—(N+R2 2—A—E—A’—N+R2 2)—Y—]k—M
(Ib)
Wherein each group is as defined above;However, repetitive unit is not with statistical arrangement (that is, being a point block arrangement).
In other preferred embodiment, polyorganosiloxane compounds can also have general formula (IIa) or (IIb):
M—Y—[—N+R2—Y—]m—[—(NR2—A—E—A’—NR2)—Y—]k—M (IIa)
M—Y—[—N+R2—Y—]m—[—(N+R2 2—A—E—A’—N+R2 2)—Y—]k—M (IIb)
Wherein each group is as defined above.In such formula, repetitive unit is not usually with statistical arrangement (that is, being a point block arrangement) yet.
Wherein, as defined above, M is
- OC (O)-Z,
-OS(O)2-Z
-OS(O2)O-Z
-OP(O)(O-Z)OH
-OP(O)(O-Z)2
Z is the saturated or unsaturated C of straight chain, ring-type or branch1-C20, or preferably C2To C18, or it is even more excellent
Selection of land hydrocarbyl group, can be inserted into has one or more-O-or-C (O)-and quilt-OH replaces.In a specific embodiment
In, M is-OC (O)-Z, derives from common carboxylic acid, specifically has the carboxylic acid more than 10 carbon atoms, such as dodecanoic acid.
In another embodiment, the recurring group containing polysiloxane-K-S-K-and polyalkylene repeat
The molar ratio of group-A-E-A'-or-A'-E-A-between 100:1 and 1:100, or be preferably ranges between 20:1 and
Between 1:20, or more preferably between 10:1 and 1:10.
In group-(N+R2—T—N+R2)-in, R can indicate the C of monovalent linear, ring-type or branch1-C20Hydrocarbyl group,
Can be inserted into has one or more-O-,-C (O)-and can be replaced by-OH, and T can indicate divalent straight, ring-type or branch
C1-C20Hydrocarbyl group, can be inserted into has-O-,-C (O)-and can be optionally substituted by a hydroxyl group.
Above-mentioned polyorganosiloxane compounds comprising quaternary ammonium functional group and ester functional group also may include: 1) including quaternary ammonium official
It can roll into a ball and not include the individual molecule of ester functional group;2) comprising the molecule of quaternary ammonium functional group and ester functional group;And 3) include
Ester functional group and the molecule for not including quaternary ammonium functional group.Although not limited by structure, above-mentioned includes quaternary ammonium functional group
It will be understood as the two-part molecule comprising some average magnitude and ratio with the polyorganosiloxane compounds of ester functional group
Mixture.
Using various simple function organic acids to generate ester.Exemplary implementation scheme includes C1-C30Carboxylic acid such as C2、C3、C8
Acid, C10-C18Carboxylic acid such as C12、C14、C16Acid, saturation, unsaturated and hydroxy-functional C18Acid, alkyl, polyether carboxylic acid, alkane
Base sulfonic acid, aryl sulfonic acid, alkyl aryl sulphonic acid, alkylsurfuric acid, alkyl, polyether sulfuric acid, one alkyl/aryl ester of phosphoric acid and di(2-ethylhexyl)phosphate
Alkyl/aryl ester.
Annexing ingredient
Aqueous base composition of the invention may include other annexing ingredients, which can be according to the institute of final products
Feature is needed by those skilled in the art to select, and the annexing ingredient be adapted so that composition beauty or it is aesthetic more
It is acceptable, or provided for them and additional use beneficial effect.Weight of such other annexing ingredients usually to press composition
Meter about 0.001% to about 10%, the horizontal exclusive use preferably no more than about 5%.
Wide variety of other additional components can be formulated into composition of the invention.These include: other conditioners, such as with
Trade name Peptein 2000 is purchased from the hydrolytic collagen of Hormel, the vitamin E by trade name Emix-d purchased from Eisai, is purchased from
The panthenol of Roche, the panthenyl ethyl ether purchased from Roche, hydrolysis of keratin, protein, plant extracts and nutriment;
Preservative, such as benzylalcohol, methyl p-hydroxybenzoate, propylparaben and imidazolidinyl urea;PH adjusting agent, such as lemon
Lemon acid, sodium citrate, succinic acid, phosphoric acid, sodium hydroxide, sodium carbonate;Colorant, such as any one of FD&C or D&C dyestuff;
Fragrance;Ultraviolet and infrared screening agent and absorbent, such as benzophenone;And anti-dandruff agent, such as zinc pyrithione.
The method for preparing product composition
Product composition of the invention A or method B preparation by the following method.
Method A
Product composition of the invention is prepared by the following method (hereafter method A), method includes the following steps:
Blend composition is prepared, which includes surfactant and high-melting fat
Fat compounds of group and beneficial agent;
Aqueous base composition is prepared separately, which includes aqueous carrier and water
Soluble polymer, wherein base composition is substantially free of detersive surfactant, decontamination surface
Activating agent is selected from anionic surfactant, zwitterionic surfactant, amophoteric surface active
Agent and their combination;
Blend composition and aqueous base composition are mixed, are scattered in aqueous basis to be formed
The discrete particle of blend composition in composition.
Preferably, when mixing, blend composition and aqueous base composition are respectively provided with lower than hard fat race
The temperature of the fusing point of compound.
Preferably, when mixing, blend composition has the hard fat being lower than include in blend composition
The temperature of the fusing point of compounds of group, and blend composition is with aqueous base composition mixing periods and later with such
Temperature.It is further preferred that aqueous base composition also has lower than included in mixture group when mixing with the blend composition
The temperature of the fusing point of the hard fat compounds of group in object is closed, and is had with blend composition mixing periods and later
Such temperature.
Therefore, when mixing, blend composition and aqueous base composition are respectively provided with lower than hard fat race
Preferably at least 2 DEG C of above-mentioned fusing point for closing object, more preferably at least 5 DEG C, still more preferably at least 10 DEG C, even more preferably extremely
Few 15 DEG C of temperature.
It is further preferred that blend composition and aqueous base composition are respectively provided with about 0 DEG C to about 50 DEG C when mixing,
More preferably about 10 DEG C to about 40 DEG C, still more preferably about 15 DEG C to about 35 DEG C of temperature.
Method B
Alternatively, product composition of the invention is prepared by the following method (hereafter method B), and this method includes following step
It is rapid:
The discrete particle of blend composition is prepared, wherein blend composition includes surfactant and hard fat
Compounds of group and beneficial agent;
Aqueous base composition is prepared separately, which includes aqueous carrier and water-soluble polymer,
Middle base composition is selected from anionic surfactant, both sexes substantially free of detersive surfactant, detersive surfactant
Ionic surface active agent, amphoteric surfactant and their combination;
Discrete particle and aqueous base composition are mixed, disperse discrete particle in aqueous base composition.
In this method B, discrete particle is preferably solid.
In method B, solvent or carrier can be used for preparing the discrete particle of blend composition.When the amount for calculating component
When, such solvent and carrier are considered as the component of aqueous base composition.
Preferably, when mixing, discrete particle and aqueous base composition are respectively provided with lower than hard fat race chemical combination
The temperature of the fusing point of object.
Preferably, when mixing, discrete particle has the hard fat compounds of group being lower than include in discrete particle
Fusing point temperature, and discrete particle has such temperature with aqueous base composition mixing periods and later.Further preferably
Ground, when mixing with discrete particle, aqueous base composition also has the hard fat race being lower than include in discrete particle
The temperature of the fusing point of compound, and with discrete particle mixing periods and later with such temperature.
Therefore, when mixing, discrete particle and aqueous base composition are respectively provided with lower than above-mentioned hard fat race
Preferably at least 2 DEG C of fusing point for closing object, more preferably at least 5 DEG C, still more preferably at least 10 DEG C, even more preferably at least 15
DEG C temperature.
It is further preferred that when mixing, discrete particle and aqueous base composition are respectively provided with about 0 DEG C to about 50 DEG C, more excellent
About 10 DEG C to about 40 DEG C of selection of land, still more preferably about 15 DEG C to about 35 DEG C of temperature.
The preparation of blend composition
In both method A and B, it is preferable that blend composition is prepared by following steps:
Melting mixing compositions are prepared, which includes surfactant and hard fat race
Object is closed, it includes hard fat compounds of group in blend composition that wherein the temperature of melting mixing compositions, which is higher than,
Fusing point;
Melting mixing compositions are cooled to the hard fat compounds of group being lower than include in blend composition
Fusing point temperature, to form blend composition.In method B, discrete particle can prepare mixed during above-mentioned cooling step
It prepares, or can be prepared after forming blend composition while polymer composition.
Preferably, the temperature of melting mixing compositions is higher than at least 2 DEG C of above-mentioned fusing point of hard fat compounds of group,
Still more preferably at least 5 DEG C, even more preferably at least 10 DEG C.The temperature of further preferably melting mixing compositions be about 30 DEG C extremely
About 150 DEG C, more preferably about 40 DEG C to about 100 DEG C, still more preferably about 50 DEG C to about 95 DEG C, even more preferably about 55 DEG C extremely
About 90 DEG C, in addition more preferably about 66 DEG C to about 90 DEG C.
Preferably, melting mixing compositions are cooled to the hard fat race being lower than include in blend composition
The temperature of the fusing point of compound, be more preferably less than include hard fat compounds of group in blend composition fusing point
At least 2 DEG C, more preferably at least 5 DEG C, still more preferably at least 10 DEG C.Further preferably by melting mixing compositions be cooled to about-
200 DEG C to about 50 DEG C, more preferably about -40 DEG C to about 50 DEG C, still more preferably about 0 DEG C to about 30 DEG C of temperature.
When in blend composition including beneficial agent
When blend composition includes also beneficial agent, blend composition can be prepared by following steps:
Melting mixing compositions are prepared, which includes surfactant and hard fat race
Object is closed, it includes hard fat compounds of group in blend composition that wherein the temperature of melting mixing compositions, which is higher than,
Fusing point;
Melting mixing compositions are cooled to the hard fat compounds of group being lower than include in blend composition
Fusing point temperature, to form blend composition,
Wherein beneficial agent can be added at any time according to the characteristic of beneficial agent, for example, can before cooling, in cooling phase
Between especially when using volatility beneficial agent such as fragrance, or after cooling, preferably after cooling at once, such as exist
After cooling in 30min, it would be beneficial to which agent is added in blend composition.
When blend composition includes beneficial agent, beneficial agent can uniformly be mixed with blend composition, and can be in group
It closes in object and forms uniform discrete particle.
Alternatively, in discrete particle, beneficial agent can form the inner core covered by shell, and the shell is by blend composition
It is formed.
When in aqueous base composition including beneficial agent
When aqueous base composition includes beneficial agent, beneficial agent can uniformly be mixed with aqueous base composition.
When aqueous base composition includes beneficial agent, beneficial agent can be added to aqueous base composition at any time
In, for example, addition blend composition and/or discrete particle before, addition blend composition and/or discrete particle it
Afterwards, and/or with discrete particle simultaneously.
Embodiment
Following embodiment further describes and illustrates the embodiment in the scope of the invention.These embodiments are only for example
It demonstrate,proves purpose and provides and be not understood as limitation of the present invention, because not departing from the spirit and scope of the invention
In the case of can have its many modification.Applicable ingredient is identified with chemical name or CTFA herein, unless limiting additionally below
It is fixed.
Product composition-M
Product composition-P
Product composition-CEx.
Component definition
* the behenyl ammonium methyl sulfate of 1BTMS/IPA:80% and 20% isopropanol
* 2 water-soluble polymers -1: (30% PEG-240/HDI is copolymerized the ADEKA NOL GT-730 provided by Adeka
Object BIS-DECYLTETRADECETH-20ETHER, 50% butanediol and 20% water)
* 3 water-soluble polymers -2: polyquaternium -37
* 4 amino silicones: being purchased from Momentive, the viscosity with 10,000mPas, and has lower formula (I):
(R1)aG3-a-Si-(-OSiG2)n-(-OSiGb(R1)2-b)m-O-SiG3-a(R1)a (I)
Wherein G is methyl;The integer that a is 1;B is 0,1 or 2, preferably 1;N is the number of 400 to about 600;M be 0 it is whole
Number;R1To meet general formula CqH2qThe univalent perssad of L, the integer that wherein q is 3, and L are-NH2
The method for preparing product composition
It is that hair-conditioning products prepared by the method for the present invention combine by the embodiment that " Ex. " is open and indicates
Object, and prepared by method described above B, and be more fully described as follows:
Prepare blend composition, the blend composition include surfactant and hard fat compounds of group and
Beneficial agent, wherein blend composition is prepared by the following method:
Melting mixing compositions are prepared, wherein the temperature of melting mixing compositions, which is higher than, is included in blend composition
In hard fat compounds of group fusing point, i.e., about 66 DEG C to about 90 DEG C;
Melting mixing compositions are cooled to the hard fat compounds of group being lower than include in blend composition
Fusing point temperature, i.e., about 0 DEG C to about 40 DEG C, to form blend composition.
Prepare the solid discrete particle being made of blend composition;
Aqueous base composition is prepared separately;
Discrete particle and aqueous base composition are mixed, both there is the height being lower than include in blend composition
The temperature of the fusing point of MELTING POINT FATTY COMPOUND, i.e., about 10 DEG C to about 40 DEG C, so that discrete particle is scattered in aqueous basis combination
In object.
Discrete particle is swollen in product composition.
It is comparative example by the hair conditioner product composition that " CEx. " is open and indicates, and when composition includes discrete
It is prepared when particle by above method B, or is prepared by a conventional method when composition does not include discrete particle.
Characteristic and conditioning beneficial effect
For some in composition above, by the following method evaluation of properties and conditioning beneficial effect.The result of assessment
It is also depicted in above.
It is that hair-conditioning products prepared by the method for the present invention combine by the embodiment that " Ex. " is open and indicates
Object may be particularly used for rinse-off use, and have many advantages.For example, product prepared by the method for the present invention
Composition provides at least one of the following: the greater flexibility of product mix rheological;The improvement of product composition
Stability;And when comprising beneficial agent beneficial agent improved deposition;And improved vision/aesthetic appearance.
For example, compared with comparative example " CEx.i ", the embodiment of the present invention can from " be dispersed in transparent/translucent containing water base
The product appearance of discrete particle in plinth composition " provides aesthetic benefit, and wherein discrete particle spreads and collapses.
Dimension disclosed herein and value are not understood as being strictly limited to cited exact numerical.On the contrary, unless in addition
It indicates, otherwise each such dimension is intended to indicate that described value and the range functionally equivalent around the value.For example, being disclosed as
The dimension of " 40mm " is intended to indicate that " about 40mm ".
Unless expressly excluded or in other words it is limited, otherwise by every herein cited document, including any intersection
Reference or related patents or application, full text are herein incorporated by reference.Reference to any document be not to its as with
Of the invention any disclosed or the claimed prior art herein the approval, or be not to its own or with appoint
The combination proposition of what one or more bibliography, the approval for suggesting or disclosing any such invention.In addition, when art in the present invention
It, should when any meaning of language or definition and any meaning or definition contradiction of same term in document incorporated by reference
Obey the meaning or definition for assigning the term in the present invention.
Although specific embodiments of the present invention have had been illustrated and described, to those skilled in the art
It is readily apparent that a number of other change and modification can be made without departing from the spirit and scope of the present invention.Therefore,
It is intended to all such change and modification for covering in appended claims and belonging in the scope of the invention.
Claims (21)
1. a kind of method for preparing product composition, the described method comprises the following steps:
Prepare blend composition, the blend composition include surfactant and hard fat compounds of group and
Beneficial agent other than the surfactant and the hard fat compounds of group;
Aqueous base composition is prepared separately, the aqueous base composition includes aqueous carrier and water-soluble polymer, wherein
The base composition is selected from substantially free of detersive surfactant, the detersive surfactant: anion surface active
Agent, zwitterionic surfactant, amphoteric surfactant and their combination;
The blend composition is mixed with the aqueous base composition, is scattered in the aqueous base composition to be formed
In the blend composition discrete particle.
2. a kind of method for preparing product composition, the described method comprises the following steps:
The discrete particle of blend composition is prepared, the discrete particle includes surfactant and hard fat race chemical combination
Object and the beneficial agent other than the surfactant and the hard fat compounds of group;
Aqueous base composition is prepared separately, the aqueous base composition includes aqueous carrier and water-soluble polymer, wherein
The base composition is selected from substantially free of detersive surfactant, the detersive surfactant: anion surface active
Agent, zwitterionic surfactant, amphoteric surfactant and their combination;
The discrete particle is mixed with the aqueous base composition, disperses the aqueous basis for the discrete particle
In composition.
3. according to the method described in claim 1, wherein by both the blend composition and the aqueous base composition
Lower than include it is described mix compounds in the hard fat compounds of group fusing point at a temperature of mix.
4. according to the method described in claim 2, wherein by both the discrete particle and the aqueous base composition low
In including to mix at a temperature of the fusing point of the hard fat compounds of group in the discrete particle.
5. method according to any of the preceding claims, wherein the blend composition passes through following steps system
It is standby:
Melting mixing compositions are prepared, the melting mixing compositions include the surfactant and the high-melting fat
Fat compounds of group, wherein it includes the height in the blend composition that the temperature of the molten mixture composition, which is higher than,
The fusing point of MELTING POINT FATTY COMPOUND;
The melting mixing compositions are cooled to the hard fat being lower than include in the blend composition
The temperature of the fusing point of compounds of group, to form the blend composition;
Wherein before cooling, the beneficial agent is added to the mixture combination during cooling and/or after cooling
In object.
6. method according to any of the preceding claims, wherein the water-soluble polymer is selected from: cation is water-soluble
Property polymer, non-ionic water-soluble polymer and their mixture.
7. method according to any of the preceding claims, wherein the water-soluble polymer has about 5,000g/mol
To the average molecular weight of about 50,000,000g/mol.
8. method according to any of the preceding claims, wherein the aqueous base composition has about 100 centipoises
To the viscosity of about 10,000,000 centipoises.
9. method according to any of the preceding claims, wherein the discrete particle does not have Maltese cross.
10. method according to any of the preceding claims, wherein the discrete particle is not coated or encapsulates.
11. method according to any of the preceding claims, wherein the discrete particle is present in the composition
Up to 1 month or longer, preferably 3 months or longer, more preferably 6 months or longer, still more preferably 12 months or longer.
12. method according to any of the preceding claims, wherein the discrete particle is in the product composition
Swelling.
13. method according to any of the preceding claims, wherein the discrete particle is not oil-in-water emulsion or water
Packet water-in-oil emulsion.
14. method according to any of the preceding claims, wherein the discrete particle is solid before swelling.
15. method according to any of the preceding claims, wherein the discrete particle is before swelling comprising pressing institute
The poidometer for stating discrete particle is less than about 50%, more preferably less than about 25%, still more preferably less than about 15% water.
16. method according to any of the preceding claims, wherein the discrete particle is before swelling comprising pressing institute
State the poidometer about 10% to about 100% of discrete particle, more preferably about 20% to about 100%, still more preferably about 40% to
About 100% surfactant and the hard fat compounds of group.
17. method according to any of the preceding claims, wherein including the surface in the discrete particle
Activating agent is hydrophobic.
18. method according to any of the preceding claims, wherein including the surface in the discrete particle
Activating agent is selected from: cationic surfactant, nonionic surfactant and their mixture more preferably wherein wrap
The surfactant being contained in the discrete particle is cationic surfactant.
19. method according to any of the preceding claims, wherein the product composition is selected from: hair care composition
Object, body care composition, face protection composition and their mixture, preferably wherein the product composition is
Hair care composition.
20. method according to any of the preceding claims, wherein the beneficial agent is selected from: silicone compounds, perfume (or spice)
Material, the colorant for being added to different colours from the color of the aqueous base composition in the discrete particle and packet
It is contained at least one of aqueous base composition ingredient incompatible incompatible reagent and their mixture.
21. method according to any of the preceding claims, wherein the beneficial agent is different from aqueous carrier and water.
Applications Claiming Priority (25)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762484919P | 2017-04-13 | 2017-04-13 | |
US201762484920P | 2017-04-13 | 2017-04-13 | |
US201762484915P | 2017-04-13 | 2017-04-13 | |
US201762484918P | 2017-04-13 | 2017-04-13 | |
US201762484917P | 2017-04-13 | 2017-04-13 | |
US201762484912P | 2017-04-13 | 2017-04-13 | |
US62/484,920 | 2017-04-13 | ||
US62/484,917 | 2017-04-13 | ||
US62/484,919 | 2017-04-13 | ||
US62/484,915 | 2017-04-13 | ||
US62/484,918 | 2017-04-13 | ||
US62/484,912 | 2017-04-13 | ||
US201762532369P | 2017-07-14 | 2017-07-14 | |
US201762532371P | 2017-07-14 | 2017-07-14 | |
US201762532365P | 2017-07-14 | 2017-07-14 | |
US201762532368P | 2017-07-14 | 2017-07-14 | |
US201762532366P | 2017-07-14 | 2017-07-14 | |
US201762532372P | 2017-07-14 | 2017-07-14 | |
US62/532,371 | 2017-07-14 | ||
US62/532,368 | 2017-07-14 | ||
US62/532,372 | 2017-07-14 | ||
US62/532,366 | 2017-07-14 | ||
US62/532,369 | 2017-07-14 | ||
US62/532,365 | 2017-07-14 | ||
PCT/US2018/027410 WO2018191574A1 (en) | 2017-04-13 | 2018-04-13 | Method of preparing a product composition comprising a discrete particle and an aqueous base composition |
Publications (2)
Publication Number | Publication Date |
---|---|
CN110494118A true CN110494118A (en) | 2019-11-22 |
CN110494118B CN110494118B (en) | 2023-11-07 |
Family
ID=62090084
Family Applications (9)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201880004357.3A Active CN109952089B (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN201880024715.7A Active CN110505865B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880024661.4A Active CN110520095B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880024653.XA Active CN110494118B (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN202310260231.5A Pending CN116172892A (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880004367.7A Active CN109996528B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880024664.8A Pending CN110573214A (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN201880004386.XA Active CN109982751B (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN201880004363.9A Active CN109952090B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201880004357.3A Active CN109952089B (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN201880024715.7A Active CN110505865B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880024661.4A Active CN110520095B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202310260231.5A Pending CN116172892A (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880004367.7A Active CN109996528B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
CN201880024664.8A Pending CN110573214A (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN201880004386.XA Active CN109982751B (en) | 2017-04-13 | 2018-04-13 | Method for preparing a product composition comprising discrete particles and an aqueous base composition |
CN201880004363.9A Active CN109952090B (en) | 2017-04-13 | 2018-04-13 | Product composition comprising discrete particles and an aqueous base composition |
Country Status (9)
Country | Link |
---|---|
US (8) | US11083676B2 (en) |
EP (10) | EP3532016B1 (en) |
JP (8) | JP6943957B2 (en) |
CN (9) | CN109952089B (en) |
BR (8) | BR112019009558B1 (en) |
CA (4) | CA3040181C (en) |
ES (1) | ES2879353T3 (en) |
MX (8) | MX2019012237A (en) |
WO (8) | WO2018191574A1 (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112019009558B1 (en) | 2017-04-13 | 2023-01-31 | The Procter & Gamble Company | METHOD FOR PREPARING A PRODUCT COMPOSITION COMPRISING A DISTINCT PARTICLE AND AN AQUEOUS BASE COMPOSITION |
CN112261931B (en) | 2018-06-05 | 2023-12-08 | 宝洁公司 | Transparent cleaning composition |
US11931441B2 (en) | 2018-10-10 | 2024-03-19 | The Procter & Gamble Company | Personal care product customized by discrete particles and method of apply thereof |
JP7328336B2 (en) | 2018-12-14 | 2023-08-16 | ザ プロクター アンド ギャンブル カンパニー | SHAMPOO COMPOSITION CONTAINING SHEET-FORMED MICROCAPSULES |
US11896689B2 (en) | 2019-06-28 | 2024-02-13 | The Procter & Gamble Company | Method of making a clear personal care comprising microcapsules |
CN114981016A (en) | 2020-02-14 | 2022-08-30 | 宝洁公司 | Bottle suitable for storing liquid compositions having an aesthetic design suspended therein |
US11633072B2 (en) | 2021-02-12 | 2023-04-25 | The Procter & Gamble Company | Multi-phase shampoo composition with an aesthetic design |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05220383A (en) * | 1990-02-23 | 1993-08-31 | L'oreal Sa | Fluid composition containing micro dispersion product of wax and cationic surface active agent and its production and application |
CN1204255A (en) * | 1995-10-16 | 1999-01-06 | 普罗克特和甘保尔公司 | Conditioning shampoo compositions having improved stability |
CN1304302A (en) * | 1998-04-03 | 2001-07-18 | 荷兰联合利华有限公司 | Hair treatment compositions |
EP1779838A1 (en) * | 2005-10-26 | 2007-05-02 | KPSS-Kao Professional Salon Services GmbH | Hair conditioning composition comprising Polyquaternium 37, fatty alcohol and non-ionic / cationic surfactant |
US20090324532A1 (en) * | 2008-06-25 | 2009-12-31 | Toshiyuki Okada | Hair conditioning composition containing a salt of cetyl trimethyl ammonium chloride, and having higher yield point |
WO2010077707A2 (en) * | 2008-12-09 | 2010-07-08 | The Procter & Gamble Company | Method for preparing personal care composition comprising surfactant and high melting point fatty compound |
WO2016054347A1 (en) * | 2014-10-03 | 2016-04-07 | The Procter & Gamble Company | Hair care composition comprising discrete particle of oily component |
Family Cites Families (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4275055A (en) | 1979-06-22 | 1981-06-23 | Conair Corporation | Hair conditioner having a stabilized, pearlescent effect |
US4795327A (en) * | 1984-03-26 | 1989-01-03 | Forest Laboratories, Inc. | Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants |
US4891214A (en) | 1986-10-23 | 1990-01-02 | Sherex Chemical Company, Inc. | Particulate emulsifiable hair conditioning composition |
AU658608B2 (en) * | 1991-03-25 | 1995-04-27 | Astellas Pharma Europe B.V. | Topical preparation containing a suspension of solid lipid particles |
KR100292708B1 (en) | 1995-10-16 | 2001-10-26 | 데이비드 엠 모이어 | Conditioning Shampoo Composition |
ATE214591T1 (en) | 1995-10-16 | 2002-04-15 | Procter & Gamble | CONDITIONING SHAMPOO COMPOSITIONS WITH IMPROVED STABILITY |
ES2228049T3 (en) * | 1998-06-05 | 2005-04-01 | Unilever N.V. | COMPOSITIONS FOR HAIR CARE AND METHOD FOR DEPOSITING POLYMERIC PARTICLES INFLATED ON THE HAIR. |
AU2309499A (en) * | 1999-01-04 | 2000-07-24 | Procter & Gamble Company, The | Hair conditioning layered gel composition containing a high melting point compound |
JP2000355519A (en) * | 1999-06-14 | 2000-12-26 | Lion Corp | Production of emulsified cosmetic |
WO2001008643A1 (en) * | 1999-07-02 | 2001-02-08 | The Procter & Gamble Company | Hair conditioning compositon comprising cationic silicone emulsion |
DE10009996B4 (en) | 2000-03-02 | 2005-10-13 | Cognis Ip Management Gmbh | Solid granules with monodisperse particle size distribution, a process for their preparation and their use |
DE10059670A1 (en) * | 2000-12-01 | 2002-06-20 | Henkel Kgaa | Use of nanoparticulate waxes in hair cosmetics |
US6878368B2 (en) | 2001-03-29 | 2005-04-12 | San-Ei Kagaku Co., Ltd. | Composition for blending to hair treating agents and a hair treating agent |
ES2249592T3 (en) | 2001-06-22 | 2006-04-01 | Unilever N.V. | HAIR CONDITIONING COMPOSITIONS. |
US8367048B2 (en) | 2002-06-04 | 2013-02-05 | The Procter & Gamble Company | Shampoo containing a gel network |
US8361450B2 (en) | 2002-06-04 | 2013-01-29 | The Procter & Gamble Company | Shampoo containing a gel network and a non-guar galactomannan polymer derivative |
US8361448B2 (en) | 2002-06-04 | 2013-01-29 | The Procter & Gamble Company | Shampoo containing a gel network |
US8349301B2 (en) | 2002-06-04 | 2013-01-08 | The Procter & Gamble Company | Shampoo containing a gel network |
US8349302B2 (en) | 2002-06-04 | 2013-01-08 | The Procter & Gamble Company | Shampoo containing a gel network and a non-guar galactomannan polymer derivative |
US7303744B2 (en) | 2002-06-04 | 2007-12-04 | Robert Lee Wells | Shampoo containing a gel network |
US8470305B2 (en) | 2002-06-04 | 2013-06-25 | The Procter & Gamble Company | Shampoo containing a gel network |
CN1703187A (en) * | 2002-10-10 | 2005-11-30 | 宝洁公司 | Hair conditioning composition comprising thickening polymer and cationic surfactant |
FR2857591B1 (en) * | 2003-07-17 | 2007-11-02 | Ethypharm Sa | PARTICLES COMPRISING AN ACTIVE INGREDIENT IN THE FORM OF CO-PRECIPITATE |
JP4114945B2 (en) * | 2003-09-24 | 2008-07-09 | ザ プロクター アンド ギャンブル カンパニー | Conditioning composition comprising aminosilicone |
GB0403879D0 (en) * | 2004-02-21 | 2004-03-24 | Unilever Plc | Hair conditioning compositions and methods of manufacture |
US20060040835A1 (en) * | 2004-08-19 | 2006-02-23 | Newkirk R S | Cleansing system and method |
MX2008000049A (en) * | 2005-07-07 | 2008-03-19 | Procter & Gamble | Conditioning compositions comprising coacervate and gel matrix. |
US20070014823A1 (en) * | 2005-07-12 | 2007-01-18 | The Procter & Gamble Company | Multi phase personal care composition comprising compositions having similar rheology profile in different phases |
WO2009158438A2 (en) * | 2008-06-25 | 2009-12-30 | The Procter & Gamble Company | Hair conditioning composition having higher yield point and higher conversion rate of fatty compound to gel matrix |
JP4613258B2 (en) * | 2009-02-03 | 2011-01-12 | 株式会社資生堂 | Hair conditioner composition and low energy production method thereof |
JP5395817B2 (en) * | 2011-01-19 | 2014-01-22 | 花王株式会社 | Vesicle composition, production method thereof and use thereof |
US20130310296A1 (en) * | 2011-02-24 | 2013-11-21 | Serena Linley Sarl | Bar soap composition with enhanced sensory properties in soft and very soft water |
CN108078797A (en) * | 2011-09-15 | 2018-05-29 | 宝洁公司 | The method for preparing the personal care composition comprising surfactant system and hard fat compounds of group |
JP2013095711A (en) * | 2011-11-02 | 2013-05-20 | Kose Corp | Oil-in-water emulsion cosmetic |
JP6071123B2 (en) * | 2012-02-10 | 2017-02-01 | 株式会社 資生堂 | Oil-in-water emulsified skin cosmetic |
JP6284608B2 (en) * | 2012-02-10 | 2018-02-28 | 株式会社 資生堂 | Oil-in-water emulsified skin cosmetic |
WO2014014053A1 (en) * | 2012-07-18 | 2014-01-23 | 花王株式会社 | Hair cosmetic |
JP2015531008A (en) * | 2012-07-19 | 2015-10-29 | ザ プロクター アンド ギャンブルカンパニー | Composition comprising a hydrophobically modified cationic polymer |
CN104507452A (en) | 2012-07-27 | 2015-04-08 | 荷兰联合利华有限公司 | Process |
BR112015001726B1 (en) | 2012-07-27 | 2019-08-27 | Unilever Nv | processes for producing a gel conditioning phase and process for manufacturing a conditioning composition |
CN104918661B (en) * | 2013-02-08 | 2017-10-24 | 宝洁公司 | Hair care composition comprising cationic polymer and anion particle |
KR20140101660A (en) | 2013-02-12 | 2014-08-20 | 가부시키가이샤 미르본 | Candelilla wax dispersion composition |
MX361103B (en) | 2013-04-05 | 2018-11-27 | Procter & Gamble | Hair care composition comprising a pre-emulsified formulation. |
US10532013B2 (en) * | 2013-05-22 | 2020-01-14 | The Procter And Gamble Company | Method of achieving improved product rheology, cosmetic consumer acceptance and deposition |
EP2818155A1 (en) | 2013-06-26 | 2014-12-31 | Kao Corporation, S.A. | Hair conditioner |
EP3049050B1 (en) * | 2013-09-27 | 2018-10-24 | The Procter and Gamble Company | Hair conditioning compositions comprising low viscosity emulsified silicone polymers |
JP2017518337A (en) | 2014-06-25 | 2017-07-06 | ザ プロクター アンド ギャンブル カンパニー | Method for preparing a hair conditioning composition comprising a monoalkylamine cationic surfactant and an anionic polymer |
MX2016016934A (en) * | 2014-06-25 | 2017-04-27 | Procter & Gamble | A method of preparing hair conditioning composition comprising mono-alkyl amine cationic surfactant, anionic polymer and polyol. |
JP6113695B2 (en) * | 2014-10-31 | 2017-04-12 | 株式会社 資生堂 | Elastic gel composition |
FR3030270B1 (en) | 2014-12-19 | 2018-03-16 | L'oreal | COSMETIC TREATMENT PROCESS AND KIT THEREFOR |
WO2017053959A1 (en) * | 2015-09-24 | 2017-03-30 | Deckner Consulting Services, Llc | High efficiency sunscreen composition |
BR112019009558B1 (en) | 2017-04-13 | 2023-01-31 | The Procter & Gamble Company | METHOD FOR PREPARING A PRODUCT COMPOSITION COMPRISING A DISTINCT PARTICLE AND AN AQUEOUS BASE COMPOSITION |
CN112261931B (en) | 2018-06-05 | 2023-12-08 | 宝洁公司 | Transparent cleaning composition |
US11931441B2 (en) | 2018-10-10 | 2024-03-19 | The Procter & Gamble Company | Personal care product customized by discrete particles and method of apply thereof |
-
2018
- 2018-04-13 BR BR112019009558-6A patent/BR112019009558B1/en active IP Right Grant
- 2018-04-13 JP JP2019525733A patent/JP6943957B2/en active Active
- 2018-04-13 JP JP2019554534A patent/JP7004740B2/en active Active
- 2018-04-13 EP EP18721625.4A patent/EP3532016B1/en active Active
- 2018-04-13 CA CA3040181A patent/CA3040181C/en active Active
- 2018-04-13 ES ES18721624T patent/ES2879353T3/en active Active
- 2018-04-13 MX MX2019012237A patent/MX2019012237A/en unknown
- 2018-04-13 CN CN201880004357.3A patent/CN109952089B/en active Active
- 2018-04-13 JP JP2019525898A patent/JP6928087B2/en active Active
- 2018-04-13 WO PCT/US2018/027410 patent/WO2018191574A1/en unknown
- 2018-04-13 WO PCT/US2018/027409 patent/WO2018191573A1/en unknown
- 2018-04-13 CN CN201880024715.7A patent/CN110505865B/en active Active
- 2018-04-13 CA CA3040183A patent/CA3040183C/en active Active
- 2018-04-13 WO PCT/US2018/027408 patent/WO2018191572A1/en unknown
- 2018-04-13 JP JP2019525897A patent/JP6943958B2/en active Active
- 2018-04-13 EP EP18721624.7A patent/EP3532015B1/en active Active
- 2018-04-13 BR BR112019009537-3A patent/BR112019009537B1/en active IP Right Grant
- 2018-04-13 EP EP18721628.8A patent/EP3609466B1/en active Active
- 2018-04-13 BR BR112019019434-7A patent/BR112019019434B1/en active IP Right Grant
- 2018-04-13 EP EP18721240.2A patent/EP3609463A1/en not_active Withdrawn
- 2018-04-13 BR BR112019009554-3A patent/BR112019009554B1/en active IP Right Grant
- 2018-04-13 JP JP2019554523A patent/JP7021249B2/en active Active
- 2018-04-13 WO PCT/US2018/027407 patent/WO2018191571A1/en unknown
- 2018-04-13 MX MX2019005579A patent/MX2019005579A/en unknown
- 2018-04-13 MX MX2019005580A patent/MX2019005580A/en unknown
- 2018-04-13 MX MX2019005581A patent/MX2019005581A/en unknown
- 2018-04-13 EP EP18721627.0A patent/EP3609582A1/en not_active Withdrawn
- 2018-04-13 MX MX2019012238A patent/MX2019012238A/en unknown
- 2018-04-13 CN CN201880024661.4A patent/CN110520095B/en active Active
- 2018-04-13 CN CN201880024653.XA patent/CN110494118B/en active Active
- 2018-04-13 WO PCT/US2018/027403 patent/WO2018191567A1/en unknown
- 2018-04-13 MX MX2019012236A patent/MX2019012236A/en unknown
- 2018-04-13 BR BR112019019442-8A patent/BR112019019442B1/en active IP Right Grant
- 2018-04-13 EP EP18721629.6A patent/EP3609467B1/en active Active
- 2018-04-13 CA CA3057703A patent/CA3057703C/en active Active
- 2018-04-13 EP EP18721626.2A patent/EP3532017B1/en active Active
- 2018-04-13 EP EP24159516.4A patent/EP4349322A2/en active Pending
- 2018-04-13 CN CN202310260231.5A patent/CN116172892A/en active Pending
- 2018-04-13 MX MX2019012235A patent/MX2019012235A/en unknown
- 2018-04-13 BR BR112019009550-0A patent/BR112019009550B1/en active IP Right Grant
- 2018-04-13 MX MX2019005578A patent/MX2019005578A/en unknown
- 2018-04-13 JP JP2019525790A patent/JP6933709B2/en active Active
- 2018-04-13 CN CN201880004367.7A patent/CN109996528B/en active Active
- 2018-04-13 EP EP24155754.5A patent/EP4342446A2/en active Pending
- 2018-04-13 WO PCT/US2018/027405 patent/WO2018191569A1/en unknown
- 2018-04-13 WO PCT/US2018/027406 patent/WO2018191570A1/en unknown
- 2018-04-13 JP JP2019554529A patent/JP6970211B2/en active Active
- 2018-04-13 CN CN201880024664.8A patent/CN110573214A/en active Pending
- 2018-04-13 WO PCT/US2018/027404 patent/WO2018191568A1/en unknown
- 2018-04-13 CN CN201880004386.XA patent/CN109982751B/en active Active
- 2018-04-13 EP EP18721239.4A patent/EP3532167A1/en active Pending
- 2018-04-13 CA CA3057701A patent/CA3057701C/en active Active
- 2018-04-13 BR BR112019019393-6A patent/BR112019019393B1/en active IP Right Grant
- 2018-04-13 BR BR112019019389-8A patent/BR112019019389B1/en active IP Right Grant
- 2018-04-13 CN CN201880004363.9A patent/CN109952090B/en active Active
- 2018-04-13 JP JP2019554530A patent/JP7048639B2/en active Active
-
2019
- 2019-06-14 US US16/441,639 patent/US11083676B2/en active Active
- 2019-06-14 US US16/441,650 patent/US20190290568A1/en not_active Abandoned
- 2019-06-14 US US16/441,604 patent/US20190290567A1/en not_active Abandoned
- 2019-06-14 US US16/441,662 patent/US20190290555A1/en not_active Abandoned
- 2019-06-14 US US16/441,588 patent/US20190307665A1/en not_active Abandoned
- 2019-06-14 US US16/441,618 patent/US11058620B2/en active Active
- 2019-06-14 US US16/441,686 patent/US10751272B2/en active Active
- 2019-06-14 US US16/441,671 patent/US11058621B2/en active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH05220383A (en) * | 1990-02-23 | 1993-08-31 | L'oreal Sa | Fluid composition containing micro dispersion product of wax and cationic surface active agent and its production and application |
CN1204255A (en) * | 1995-10-16 | 1999-01-06 | 普罗克特和甘保尔公司 | Conditioning shampoo compositions having improved stability |
CN1304302A (en) * | 1998-04-03 | 2001-07-18 | 荷兰联合利华有限公司 | Hair treatment compositions |
EP1779838A1 (en) * | 2005-10-26 | 2007-05-02 | KPSS-Kao Professional Salon Services GmbH | Hair conditioning composition comprising Polyquaternium 37, fatty alcohol and non-ionic / cationic surfactant |
US20090324532A1 (en) * | 2008-06-25 | 2009-12-31 | Toshiyuki Okada | Hair conditioning composition containing a salt of cetyl trimethyl ammonium chloride, and having higher yield point |
WO2010077707A2 (en) * | 2008-12-09 | 2010-07-08 | The Procter & Gamble Company | Method for preparing personal care composition comprising surfactant and high melting point fatty compound |
WO2016054347A1 (en) * | 2014-10-03 | 2016-04-07 | The Procter & Gamble Company | Hair care composition comprising discrete particle of oily component |
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN110494118A (en) | The method of product composition of the preparation comprising discrete particle and aqueous base composition | |
CN106456504A (en) | Hair conditioning composition comprising amidoamine cationic surfactant and deposition polymer, and having lower ph | |
CN112804984A (en) | Personal care products customized from discrete particles and methods of applying same |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |