CN110474612A - A kind of variable gain amplifier, application method and bio signal handle chip - Google Patents
A kind of variable gain amplifier, application method and bio signal handle chip Download PDFInfo
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- CN110474612A CN110474612A CN201910660360.7A CN201910660360A CN110474612A CN 110474612 A CN110474612 A CN 110474612A CN 201910660360 A CN201910660360 A CN 201910660360A CN 110474612 A CN110474612 A CN 110474612A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/024—Detecting, measuring or recording pulse rate or heart rate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03F—AMPLIFIERS
- H03F3/00—Amplifiers with only discharge tubes or only semiconductor devices as amplifying elements
- H03F3/45—Differential amplifiers
- H03F3/45071—Differential amplifiers with semiconductor devices only
- H03F3/45479—Differential amplifiers with semiconductor devices only characterised by the way of common mode signal rejection
- H03F3/45928—Differential amplifiers with semiconductor devices only characterised by the way of common mode signal rejection using IC blocks as the active amplifying circuit
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03G—CONTROL OF AMPLIFICATION
- H03G3/00—Gain control in amplifiers or frequency changers
- H03G3/20—Automatic control
- H03G3/30—Automatic control in amplifiers having semiconductor devices
- H03G3/3036—Automatic control in amplifiers having semiconductor devices in high-frequency amplifiers or in frequency-changers
- H03G3/3042—Automatic control in amplifiers having semiconductor devices in high-frequency amplifiers or in frequency-changers in modulators, frequency-changers, transmitters or power amplifiers
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- H—ELECTRICITY
- H03—ELECTRONIC CIRCUITRY
- H03F—AMPLIFIERS
- H03F2200/00—Indexing scheme relating to amplifiers
- H03F2200/435—A peak detection being used in a signal measuring circuit in a controlling circuit of an amplifier
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Abstract
The invention discloses a kind of variable gain amplifier, application method and bio signals to handle chip, the variable gain amplifier includes variable-gain amplification circuit and detection control circuit, the wherein variable-gain amplification circuit, including the first variable gain control unit, the second variable gain control unit and operational amplification circuit, for amplifying input signal and exporting amplified signal；The detection control circuit, for detecting the amplified signal, according to the peak value of the amplified signal and preset range be compared and output adjustment described in the first variable gain control unit and the second variable gain control unit gain control signal to adjust the gain of the variable gain amplifier.Embodiment provided by the invention effectively improves the response speed of switch capacitor filter by variable-gain amplification circuit and detection control circuit, reduces circuit and enters steady operation required time.
Description
Technical field
The present invention relates to technical field of integrated circuits, more particularly to a kind of variable gain amplifier, application method and life
Object signal processing chip.
Background technique
In recent years, popularizing with healthy wearable device, the chip for detecting and handling bio signal has widely
Development prospect.In order to analyze the health status of human body preferably from bio signal, reduce distorted signals, the anti-interference energy of enhancing
Power becomes the significant design requirement of such cake core.General sensor bio signal collected contains a large amount of non-phase
Hope component, and effective bio signal component accounts for the usual very little of ratio of resultant signal.With PPG detection method heart rate signal collected
For, active constituent accounts for 10% or less resultant signal amount.Therefore, it is necessary to be amplified to extracted bio signal.Due to
The signal intensity difference of different crowd is larger, and the amplifier using fixed gain amplifier may not have commonly used range.If
Gain is less than normal, is unfavorable for the subtle bio signal characteristic point of sample circuit precise acquisition；If gain is bigger than normal, it is likely that cause to satisfy
And distortion.
Meanwhile many measurements happen when human motion, for example measure heart rate value during running, if this
When it is bigger than normal to the gain amplifier of signal, then to move noise in bring passband and saturated phenomenon occur, which will drown out
The heart rate signal component of effect.
Therefore, in order to adapt to widely apply crowd, enhance the ability of anti motion interference, need in bio signal processing
Gain-changeable amplifier circuit is added in chip.
Summary of the invention
At least one to solve the above-mentioned problems, first aspect present invention provides a kind of variable gain amplifier, including can
Variable-gain amplifying circuit and detection control circuit, wherein
The variable-gain amplification circuit, including the first variable gain control unit, the second variable gain control unit and
Operational amplification circuit, for amplifying input signal and exporting amplified signal；
The detection control circuit, for detecting the amplified signal, according to the peak value of the amplified signal and default model
Enclose be compared, and output adjustment described in the first variable gain control unit and the second variable gain control unit gain control
Signal is to adjust the gain of the variable gain amplifier.
Further, the variable-gain amplification circuit further includes feedback capacity.
Further, first variable gain control unit includes sampling variable capacitance and four sampling switch；
Second variable gain control unit includes feedback variable capacitance and four feedback switch.
Further, clock frequency of the clock frequency of the sampling switch and feedback switch relative to the input signal
Meet over-sampling.
Further, the detection control circuit includes peak detection circuit and gain controller, wherein
The peak detection circuit, for detecting the amplified signal and exporting the peak value of amplified signal；
The gain controller, for being compared according to the peak value and the preset range, and according to the knot of comparison
Fruit exports the gain control signal to adjust the gain of the variable gain amplifier.
Further, the gain controller includes first comparator, the second comparator and Strobe Controller, wherein
The first comparator is compared for being compared the peak value with the first threshold pre-seted and exporting first
As a result；
Second comparator is compared for being compared the peak value with the second threshold pre-seted and exporting second
As a result；
The Strobe Controller, for exporting the gain control signal according to the first comparison result and the second comparison result
To adjust the gain of the variable gain amplifier.
Second aspect of the present invention provides a kind of application method using variable gain amplifier described in first aspect, packet
It includes:
Variable-gain amplification circuit is put by the first variable gain control unit, the second variable gain control unit and operation
Big circuit amplification input signal simultaneously exports amplified signal；
It detects control circuit and detects the amplified signal, compared according to the peak value of the amplified signal and preset range
, and output adjustment described in the first variable gain control unit and the second variable gain control unit gain control signal.
Further, first variable gain control unit includes sampling variable capacitance and four sampling switch, described
Second variable gain control unit includes feedback variable capacitance and four feedback switch；
The application method further include:
The clock frequency of the sampling switch and feedback switch met relative to the clock frequency of the input signal adopts
Sample.
Further, the detection control circuit includes peak detection circuit and gain controller；
The detection control circuit detects the amplified signal, is carried out according to the peak value of the amplified signal and preset range
The gain control signal of first variable gain control unit described in comparison and output adjustment and the second variable gain control unit tool
Body includes:
The peak detection circuit detects the amplified signal and exports the peak value of amplified signal；
The gain controller is compared according to the peak value and the preset range, and is exported according to the result of comparison
The gain control signal.
Third aspect present invention provides a kind of bio signal processing chip, amplifies including variable gain described in first aspect
Device.
Beneficial effects of the present invention are as follows:
The present invention formulates at a kind of variable gain amplifier, application method and bio signal for existing problem at present
Chip is managed, the response speed of switch capacitor filter is effectively improved by variable-gain amplification circuit and detection control circuit, is subtracted
The time required to few circuit enters steady operation, the requirement of bio signal processing can satisfy.
Detailed description of the invention
Specific embodiments of the present invention will be described in further detail with reference to the accompanying drawing.
Fig. 1 shows a kind of negative feedback closed loop variable gain amplifier in the prior art；
Fig. 2 shows another negative feedback closed loop variable gain amplifiers in the prior art；
Fig. 3 shows the structural block diagram of variable gain amplifier described in one embodiment of the present of invention；
Fig. 4 shows the circuit diagram of variable gain amplifier described in one embodiment of the present of invention；
Fig. 5 shows the circuit diagram of variable gain amplifier described in another embodiment of the invention；
Fig. 6 shows the gain linearity degree test result of variable gain amplifier described in one embodiment of the present of invention；
Fig. 7 shows the spectral characteristic test result of variable gain amplifier described in one embodiment of the present of invention；
Fig. 8 shows the flow chart of the application method of variable gain amplifier described in one embodiment of the present of invention.
Specific embodiment
In order to illustrate more clearly of the present invention, the present invention is done further below with reference to preferred embodiments and drawings
It is bright.Similar component is indicated in attached drawing with identical appended drawing reference.It will be appreciated by those skilled in the art that institute is specific below
The content of description is illustrative and be not restrictive, and should not be limited the scope of the invention with this.
Traditional open-loop gain control amplifier is widely used in the demodulation in the high frequencies such as wireless receiving or radio frequency system
Part, their amplitude of oscillation, the distortion factor are difficult to meet the requirement of bio signal processing.
In the prior art, the closed loop variable gain amplifier of negative-feedback technology is usually utilized, as shown in Figure 1, can to use
Power transformation hinders R2Realize the closed loop variable gain amplifier of negative-feedback, the then gain of the amplifier are as follows:The increasing
Benefit and R1And R2Resistance value it is related, although meet the requirements in terms of the amplitude of oscillation and the distortion factor can be to a certain degree for the operational amplifier
On meet the requirements, but the operational amplifier needs stronger ohmic load ability, therefore increases power consumption and area cost.Such as figure
2 show another closed loop variable gain amplifier for utilizing negative-feedback technology, using variable capacitance C2And R1Parallel connection is realized negative anti-
Feedback, the then gain of the amplifier are as follows:The gain and C1And C2Resistance value it is related, can be in the amplitude of oscillation
It meets the requirements and can meet the requirements to a certain extent in terms of the distortion factor, although the operational amplifier does not require ohmic load energy
Power, but feedback capacity C2With resistance R1Form high pass characteristic, for meet the low frequency requirement of bio signal then need to be arranged it is biggish
Capacitance resistance value, therefore reduce precision, increase chip cost.Also, Fig. 1 and closed loop variable gain shown in Fig. 2 are put
Big device can only provide the gain greater than 1, it is difficult to meet the practical application request in bio signal treatment process.
To solve the above problems, as shown in figure 3, one embodiment of the present of invention provides a kind of variable gain amplifier, packet
Variable-gain amplification circuit and detection control circuit are included, wherein the variable-gain amplification circuit, including the first variable gain control
Unit, the second variable gain control unit and operational amplification circuit processed, for amplifying input signal and exporting amplified signal；It is described
Detection control circuit is compared, simultaneously for detecting the amplified signal according to the peak value of the amplified signal and preset range
The gain control signal of first variable gain control unit and the second variable gain control unit described in output adjustment is to adjust
State the gain of variable gain amplifier.
In a specific example, as shown in figure 4, the variable gain amplifier include variable-gain amplification circuit and
Detect control circuit, input signal Vin, output signal Vout, wherein variable-gain amplification circuit uses switched capacitor technique
To adapt to the low frequency characteristic of bio signal, to input signal VinIt amplifies and exports Vout.In the present embodiment, described variable
Gain amplifying circuit includes the first variable gain control unit, the second variable gain control unit and operational amplification circuit.
In view of needing to sample the fine feature point of bio signal, in a preferred embodiment, described first is variable
Gain control unit, the second variable gain control unit clock frequency met relative to the clock frequency of the input signal
Sampling.I.e. to be much higher than input signal VinTwice of bandwidth or more of frequency samples it, and over-sampling can be by quantizing noise
It pushes away toward higher frequency, the aliasing by using the low-pass filter of more higher cutoff frequency to avoid sampled signal, can effectively change
Kind signal resolution simultaneously reduces noise.
Specifically, in the present embodiment the first variable gain control unit and the second variable gain control unit sample frequency
fclkFrequency be input signal Vin10 times of frequency.First variable gain control unit includes sampling variable capacitance C1With
Four sampling switch, the sampling variable capacitance C1Form same phase switching capacity with sampling switch, then it is equivalent with phase switching capacity
Resistance are as follows:
Similarly, second variable gain control unit includes feeding back variable capacitance C2 and four feedback switch, described anti-
It presents variable capacitance C2 and feedback switch forms phase-veversal switch capacitor, then the resistance of phase-veversal switch capacitor equivalent are as follows:
In view of easily causing burr phenomena using switching capacity, in a preferred embodiment, the variable gain
Amplifying circuit further includes feedback capacity.As shown in figure 4, feedback capacity CfIt is in parallel with phase-veversal switch capacitor, it can effectively reduce open
Burr phenomena brought by powered-down appearance, so that output signal VoutIt is more smooth, then the transmitting of programmable gain amplifier amplifying circuit
Equation are as follows:
The then low-frequency gain of the programmable gain amplifier amplifying circuit are as follows:
Specifically, the bandwidth of -3dB of the programmable gain amplifier amplifying circuit are as follows:
In the present embodiment, by detection control circuit to the amplified signal V of outputoutIt is detected, by amplified signal
VoutIt is compared with preset range, control signal is exported to adjust first variable gain control unit according to comparison result
With the gain control signal of the second variable gain control unit, to realize adjustment to the variable-gain amplifier gain.
In a preferred embodiment, as shown in figure 5, the detection control circuit includes peak detection circuit and gain
Controller, wherein the peak detection circuit, for detecting the amplified signal and exporting the peak value of amplified signal；The gain
Controller exports the gain control for being compared according to the peak value and the preset range, and according to the result of comparison
Signal processed is to adjust the gain of the variable gain amplifier.
Specifically, the peak detection circuit detects output voltage VoutPeak value, and the and expectation peak ranges that pre-set
It is compared, high level upper limit V is arranged in the preset rangeCHWith low level lower limit VCL, by output voltage VoutPeak value difference
Pass through comparator and VCHAnd VCLIt is compared and obtains comparison result Di0And Di1, by Di0And Di1Input gain controller, by increasing
Beneficial controller generates control signal DV to adjust the gain of the variable-gain amplification circuit.It is embodied in, signal will be controlled
DV is transmitted separately to the first variable gain control unit and the second variable gain control unit to adjust sampling variable capacitance C1With
Feed back variable capacitance C2。
In a preferred embodiment, the gain controller includes first comparator, the second comparator and gating control
Device processed, wherein the first comparator, for the peak value to be compared with the first threshold pre-seted and exports the first ratio
To result；Second comparator is compared for being compared the peak value with the second threshold pre-seted and exporting second
As a result；The Strobe Controller, for according to the first comparison result and the second comparison result export the gain control signal with
Adjust the gain of the variable gain amplifier.
Realize gain control function using first comparator, the second comparator and traditional controller: described first compares
The first threshold of device is VCH, by output voltage VoutPeak value and VCHThe first comparison result D of output is comparedi0；Similarly, described
The second threshold of second comparator is VCL, by output voltage VoutPeak value and VCLThe first comparison result D of output is comparedi1；
By Di0And Di1Strobe Controller is inputted, Strobe Controller is according to Di0And Di1Outputing gain control signal DV.
If output voltage VoutPeak value be greater than VCH, then generate control signal DV and control C1And C2, according to formula (1) and
The gain of formula (2) reduction variable gain amplifier；If the peak value of output voltage Vout is less than VCL, then control signal DV is generated simultaneously
Control C1And C2, increase the gain of variable gain amplifier according to formula (1) and formula (2)；If at the peak value of output voltage Vout
In VCHAnd VCLBetween, keep current gain constant.
Using variable gain amplifier provided in this embodiment, as shown in fig. 6, the control code corresponding variable capacitor of abscissa
Different capacitances, ordinate is gain, as we know from the figure when variable capacitance value difference, when the frequency of the bio signal of input
Rate is 0.5Hz, and the linearity of the gain of the variable gain amplifier reaches 0.9998, and can satisfy the amplification to bio signal needs
It asks.Also, as shown in fig. 7, abscissa is the frequency values of the bio signal of input, ordinate is gain, be can be changed as we know from the figure
The asynchronous gain curve of capacitor value has preferable spectral characteristic in low frequency field, i.e., the described variable gain amplifier is low
There is preferable spectral characteristic in frequency field, is suitable for bio signal, can amplify for bio signal and provide suitable gain, reduce
Distorted signals simultaneously enhances anti-interference ability.
Corresponding with variable gain amplifier provided by the above embodiment, one embodiment of the application also provides a kind of benefit
With the application method of above-mentioned variable gain amplifier, due to application method provided by the embodiments of the present application and above-mentioned several embodiments
The variable gain amplifier of offer is corresponding, therefore is also applied for application method provided in this embodiment in aforementioned embodiments,
It is not described in detail in the present embodiment.
As shown in figure 8, one embodiment of the application also provides a kind of user using above-mentioned variable gain amplifier
Method, comprising: variable-gain amplification circuit is put by the first variable gain control unit, the second variable gain control unit and operation
Big circuit amplification input signal simultaneously exports amplified signal；It detects control circuit and detects the amplified signal, believed according to the amplification
Number peak value and preset range be compared, and output adjustment described in the first variable gain control unit and the second variable gain control
The gain control signal of unit processed.
In an alternative embodiment, first variable gain control unit includes that sampling variable capacitance and four adopt
Sample switch, second variable gain control unit include feedback variable capacitance and four feedback switch；The application method is also
It include: that the clock frequency of the sampling switch and feedback switch meets over-sampling relative to the clock frequency of the input signal.
In another alternative embodiment, the detection control circuit includes peak detection circuit and gain controller；
The detection control circuit detects the amplified signal, is compared, simultaneously according to the peak value of the amplified signal and preset range
The gain control signal of first variable gain control unit and the second variable gain control unit described in output adjustment specifically includes:
The peak detection circuit detects the amplified signal and exports the peak value of amplified signal；The gain controller is according to the peak
Value and the preset range are compared, and export the gain control signal according to the result of comparison.
One embodiment of the application also provides a kind of bio signal processing chip, including above-mentioned variable gain amplifier.
The health status that human body can be analyzed according to bio signal reduces distorted signals and enhances anti-interference ability.
The present invention formulates at a kind of variable gain amplifier, application method and bio signal for existing problem at present
Chip is managed, the response speed of switch capacitor filter is effectively improved by variable-gain amplification circuit and detection control circuit, is subtracted
The time required to few circuit enters steady operation, the requirement of bio signal processing can satisfy.
Obviously, the above embodiment of the present invention be only to clearly illustrate example of the present invention, and not be pair
The restriction of embodiments of the present invention may be used also on the basis of the above description for those of ordinary skill in the art
To make other variations or changes in different ways, all embodiments can not be exhaustive here, it is all to belong to this hair
The obvious changes or variations that bright technical solution is extended out are still in the scope of protection of the present invention.
Claims (10)
1. a kind of variable gain amplifier, which is characterized in that including variable-gain amplification circuit and detection control circuit, wherein
The variable-gain amplification circuit, including the first variable gain control unit, the second variable gain control unit and operation
Amplifying circuit, for amplifying input signal and exporting amplified signal；
The detection control circuit, for detecting the amplified signal, according to the peak value of the amplified signal and preset range into
The gain control signal of first variable gain control unit and the second variable gain control unit described in row comparison and output adjustment
To adjust the gain of the variable gain amplifier.
2. variable gain amplifier according to claim 1, which is characterized in that the variable-gain amplification circuit further includes
Feedback capacity.
3. variable gain amplifier according to claim 1, which is characterized in that
First variable gain control unit includes sampling variable capacitance and four sampling switch；
Second variable gain control unit includes feedback variable capacitance and four feedback switch.
4. variable gain amplifier according to claim 3, which is characterized in that the sampling switch and feedback switch when
Clock frequency meets over-sampling relative to the clock frequency of the input signal.
5. variable gain amplifier according to claim 1, which is characterized in that the detection control circuit includes peak value inspection
Slowdown monitoring circuit and gain controller, wherein
The peak detection circuit, for detecting the amplified signal and exporting the peak value of amplified signal；
The gain controller, for being compared according to the peak value and the preset range, and it is defeated according to the result of comparison
The gain control signal is out to adjust the gain of the variable gain amplifier.
6. variable gain amplifier according to claim 5, which is characterized in that the gain controller compares including first
Device, the second comparator and Strobe Controller, wherein
The first comparator compares knot for being compared the peak value with the first threshold pre-seted and exporting first
Fruit；
Second comparator compares knot for being compared the peak value with the second threshold pre-seted and exporting second
Fruit；
The Strobe Controller, for exporting the gain control signal according to first comparison result and the second comparison result
To adjust the gain of the variable gain amplifier.
7. a kind of application method using the variable gain amplifier of any of claims 1-6, which is characterized in that packet
It includes:
Variable-gain amplification circuit passes through the first variable gain control unit, the second variable gain control unit and operation amplifier electricity
Road amplification input signal simultaneously exports amplified signal；
It detects control circuit and detects the amplified signal, be compared, simultaneously according to the peak value of the amplified signal and preset range
The gain control signal of first variable gain control unit and the second variable gain control unit described in output adjustment.
8. application method according to claim 7, which is characterized in that
First variable gain control unit includes sampling variable capacitance and four sampling switch, the second variable gain control
Unit processed includes feedback variable capacitance and four feedback switch；
The application method further include:
The clock frequency of the sampling switch and feedback switch meets over-sampling relative to the clock frequency of the input signal.
9. application method according to claim 7, which is characterized in that
The detection control circuit includes peak detection circuit and gain controller；
The detection control circuit detects the amplified signal, is compared according to the peak value of the amplified signal and preset range
And output adjustment described in the first variable gain control unit and the second variable gain control unit gain control signal it is specific
Include:
The peak detection circuit detects the amplified signal and exports the peak value of amplified signal；
The gain controller is compared according to the peak value and the preset range, and according to the output of the result of comparison
Gain control signal.
10. a kind of bio signal handles chip, which is characterized in that including variable gain of any of claims 1-6
Amplifier.
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| US20090001998A1 (en) * | 2006-02-07 | 2009-01-01 | Kiyoshi Tateishi | Capacitance Detecting Apparatus |
| WO2014080586A1 (en) * | 2012-11-22 | 2014-05-30 | パナソニック株式会社 | Variable-gain amplifier and tuner system equipped with same |
| CN210168018U (en) * | 2019-05-31 | 2020-03-20 | 华润半导体（深圳）有限公司 | Variable gain amplifier and biological signal processing chip |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117833846A (en) * | 2024-01-05 | 2024-04-05 | 海底鹰深海科技股份有限公司 | Variable gain amplification circuit and variable gain amplification method |
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| CN210168018U (en) | 2020-03-20 |
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