CN110464687A - A kind of composition for repairing striae of pregnancy scar - Google Patents

A kind of composition for repairing striae of pregnancy scar Download PDF

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Publication number
CN110464687A
CN110464687A CN201910885081.0A CN201910885081A CN110464687A CN 110464687 A CN110464687 A CN 110464687A CN 201910885081 A CN201910885081 A CN 201910885081A CN 110464687 A CN110464687 A CN 110464687A
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parts
pregnancy
vitamin
striae
scar
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温军海
段丽杰
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Individual
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    • AHUMAN NECESSITIES
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
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    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
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    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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    • A61K8/60Sugars; Derivatives thereof
    • A61K8/602Glycosides, e.g. rutin
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    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
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    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The invention discloses a kind of compositions for repairing striae of pregnancy scar, this includes: the ingredient including following mass fraction for treating the combination medicament of striae of pregnancy scar: 10-20 parts of isoflavones, 2-10 parts of Troxerutin, 5-15 parts of arasaponin, 3-8 parts of general ginsenoside, 5-15 parts of vitamin B2, 5-10 parts of vitamin B5, 3-10 parts of vitamin B6, 3-15 parts of vitamin E, 3-15 parts of tranexamic acid, 5-20 parts of glycerol, 5-10 parts of allantoin, 0.1-1 parts of sodium benzoate, 10-20 parts of water phase auxiliary agent, 10-20 parts of oily phase auxiliary agent, the present invention can directly smear use, method is simple and effective, have the function of repairing striae of pregnancy scar, promote skin metabolism, it is raw to increase collagen At promotion skin elasticity improves colour of skin dimness pigmentation phenomenon.

Description

A kind of composition for repairing striae of pregnancy scar
Technical field
The present invention relates to a kind of compositions, and in particular to a kind of composition for repairing striae of pregnancy scar.
Background technique
There is 90% or so pregnant woman that can generate different degrees of striae of pregnancy, itself existing constitution reason of the generation of striae of pregnancy And the reason of itself antenatal maintenance, also there is genetic cause.You ring at twilight gestational period load-bearing, and the bulge of abdomen keeps the elastic force of skin fine Dimension and collagenous fibres because external force pull due to by different degrees of damage or fracture, thinning of skin attenuates, and abdominal skin will appear The wavy decorative pattern of some width differences, pink or aubergine different in size.After production, the elastomer of fracture is gradually obtained To repair, but it is difficult to be restored to pervious state.And the crackle on original skin just fades gradually, eventually becomes argenteous pregnant It is pregnent line.
Striae of pregnancy mainly appears on stomach wall, it is also possible to appear in outside, buttocks, chest, rear waist and arm in thigh Etc..Primipara is the most obvious.Once striae of pregnancy occur would not disappear, and with cutis laxa, breast tenesmus, stomach fat Accumulation, has seriously affected the posture and physical and mental health in women's postpartum.With the raising of people's aesthetic standards, for disappearing for striae of pregnancy Except market is increasing.The method of the reparation striae of pregnancy of routine has on the market at present:
1 micropin invasive surgery, it is such it is minimally invasive be using " micropin " also more tiny than 30G fine needle carry out aculea movement, stimulation The wound self-healing ability of skin corium promotes Collagen Proliferation, can make the thickness hyperplasia of skin epidermis, uses and fills up striae of pregnancy recess Place;
The treatment of 2 laser grindings, transmitting specific wavelength pulse width laser selectively penetrate epidermis, stimulate impaired collagen layer, New collagen tissue is generated, new collagen tissue gradually repairs impaired collagen layer with normal growth rate, improves the line of skin Reason and state, significant reduce mitigate striae of pregnancy appearance;
3 radium-shine removal striaes of pregnancy, radium-shine rhytidectomy is that a kind of new smoothing wrinkle recently in fashion goes scar mode, in the U.S. and Europe Why very hot continent beauty circle is, one of them is most important the reason is that clinical practice proves, it has the scars such as acne bright The size wrinkle of aobvious curative effect, the parts of body such as neck line, striae of pregnancy having a headache very much to people has special role.
Although the above method for treatment striae of pregnancy have certain effect, pure to hurt growth-promoting surgical technic, no The internal factor of nutrition supply and metabolic problems required for considering later period skin revitalization is gone, often existing treatment striae of pregnancy is most Whole effect is not ideal, the postoperative pigmentation phenomenon and operative failure risk that can generate larger proportion often.
Summary of the invention
(1) technical problems to be solved
In order to overcome the shortage of prior art, it is proposed that a kind of composition for repairing striae of pregnancy scar, to solve above-mentioned ask Topic.
(2) technical solution
The present invention is achieved through the following technical solutions: the invention proposes a kind of composition for repairing striae of pregnancy scar, packets Include following composition according to parts by weight, 10-20 parts of isoflavones, 2-10 parts of Troxerutin, 5-15 parts of arasaponin, people Join saponin(e 3-8 parts, 5-15 parts of vitamin B2,5-10 parts of vitamin B5,3-10 parts of vitamin B6,3-15 parts of vitamin E, ammonia 3-15 parts of first naphthenic acid, 5-20 parts of glycerol, 5-10 parts of allantoin, 5-10 parts of Sodium Hyaluronate, 0.1-1 parts of sodium benzoate, water phase help 10-20 parts of agent, oily 10-20 parts of phase auxiliary agent.
(3) beneficial effect
The present invention compared with the existing technology, has the advantages that
A kind of composition for reparation striae of pregnancy scar that the present invention mentions, can directly smear use, and method is simple and effective, Have the function of repairing striae of pregnancy scar, promote skin metabolism, increases collagen and generate, promote skin elasticity, improve Colour of skin dimness pigmentation phenomenon;Promote new vascular generation to promote Doppler flow mapping, for skin histology generate needed for nutrition at Divide and high-speed channel be provided, promotes the effective monomer of hematopoiesis, can constantly promote the proliferation of people's bone marrow granulocyte, hemopoietic progenitor cell of red blood cell line, Have additional nutrients the absolute quantity of ingredient and oxygen transportation Carrier erythrocytes.Make skin smooth, it is soft flexible, it delays senescence, also It can inhibit the generation of melanin.Nutritional ingredient is provided for skin periphery, enhances in the metabolic process of skin protein to regulate and control to make With facilitating the generation of energy, keep skin vigor, promote activities of epidermal growth factor, accelerate skin lesion healing, promoting skin just It is frequently grown.
If there is quick-acting haemostatic powder, resist for the convalescence after Miles operation of laser treatment and micropin minimally-invasive treatment striae of pregnancy Allergy, anti-inflammatory effects can reduce operation risk with accelerating wound healing, pachyderma, reduce the heavy phenomenon of color.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
It is a kind of repair striae of pregnancy scar composition, the combination medicament for being used to treat striae of pregnancy scar include: including with The ingredient of lower mass fraction: 10-20 parts of isoflavones, 2-10 parts of Troxerutin, 5-15 parts of arasaponin, 3-8 General ginsenoside, 5-15 parts of the vitamin B2,5-10 parts of vitamin B5,3-10 parts of vitamin B6,3-15 parts of dimension of part Raw E, 3-15 parts of tranexamic acid of element, 5-20 parts of glycerol, 5-10 parts of allantoin, 0.1-1 parts of sodium benzoate, water phase auxiliary agent 10-20 parts, 10-20 parts of oily phase auxiliary agent.
In the above-described embodiments, a kind of for treating the composition of striae of pregnancy scar, belong to plant extracts and Western medicine phase In conjunction with treatment technology formula.For treating the drug of striae of pregnancy scar, using Radix Notoginseng, ginseng, bean plant extract component, knot Vitamin, tranexamic acid are closed, allantoin etc. is made, and has the function of repairing striae of pregnancy scar, promotes skin metabolism, increases Collagen generates, and promotes skin elasticity, improves colour of skin dimness pigmentation phenomenon;
In the ingredient of above-mentioned medicament, isoflavones is flavone compound, is the one kind time formed in soybean growth Grade metabolite, is a kind of bioactive substance.Due to being to be extracted from plants, there is similar structure to estrogen, has female sharp Element effect, the side effect without using estrogen.Therefore isoflavones is also known as phytoestrogen.The female of isoflavones swashs Plain function influence to hormone secretion, metabolic biology activity, protein synthesis, growth factor activity;It can promote collagen Synthesis increases skin elasticity, promotes activities of epidermal growth factor, accelerates skin lesion healing.
Troxerutin, which has, inhibits red blood cell and platelet aggregation effect, prevents thrombosis, while can increase oxygen in blood Content, improve microcirculation, promote new vascular generation to promote Doppler flow mapping, for skin histology generate needed for nutritional ingredient mention For high-speed channel.
Arasaponin is to extract effective medicinal ingredient from high-quality Radix Notoginseng according to extracting and developing technology including more than 20 kinds Saponin(e active material, 17 kinds of microelements, albumen, vitamin abundant, polysaccharide etc..It is living with platelet surface is significantly reduced Property, inhibit platelet adhesion reaction and aggregation, antithrombus formation, improve the effects of microcirculation, while thering is proliferation to make hematopoietic progenitor cells With, research it has also been found that arasaponin in Rg1 and Rb1 be promote hematopoiesis effective monomer, can constantly promote people's bone marrow granulocyte, The proliferation of hemopoietic progenitor cell of red blood cell line, the absolute quantity of have additional nutrients ingredient and oxygen transportation Carrier erythrocytes.
General ginsenoside is the main component of ginseng extract.Ginseng extract can make skin smooth, soft flexible, prolong Slow aging, can also inhibit the generation of melanin.There is no any pessimal stimulation to skin, capillary of skin can be expanded, promotees It is recycled into skin blood, increases skin-nourishing, adjust the water and oil balance of skin, prevent skin dehydration, hardening, corrugation.
Tranexamic acid can be with the lysine binding sites (LBS) at the affine position of fibrin on fibrinolysin and plasminogen Strong adsorption has suppressed fibrinolysin, plasminogen in conjunction with fibrin, to consumingly inhibit the fiber caused by fibrinolysin Protein breakdown shows powerful hemostasis, antiallergic action, anti-inflammatory effects.The generation of melanin needs tyrosine and junket ammonia The participation of sour enzyme, could allow melanocyte synthesis of melanin, and tranexamic acid and tyrosine are similar in chemical structure, have One hydroxyl can fight for tyrosinase, and then the catalytic action for interfering tyrosinase to be metabolized tyrosine with tyrosine, thus Reduce the synthesis of melanin, the i.e. effect of Reverse transcriptase tyrosinase.
The use of vitamin B complex and vitamin E, mainly periphery provide nutritional ingredient, enhance the metabolic process of protein Middle regulating and controlling effect facilitates the generation of energy, keeps skin vigor, accelerates wound healing, promotes skin normal growth.
Embodiment 1
A kind of composition for repairing striae of pregnancy scar, is made of the raw material of following parts by weight: 15 parts of isoflavones, 5 parts of Troxerutin, 8 parts of arasaponin, 8 parts of general ginsenoside, 5 parts of vitamin B2,10 parts of vitamin B5,5 Vitamin B6,10 parts of the vitamin E, 10 parts of tranexamic acid, 5 parts of glycerol, 2 parts of allantoin, 5 parts of hyaluronic acid of part Sodium, 1 part of sodium benzoate, 3 parts of EDETATE SODIUM, 4 parts of ceteareth -10,2 parts of cetostearyl alcohol, 300 parts of water, fourth two 5 parts of alcohol.
The preparation method of composition of above-mentioned treatment striae of pregnancy scar, carries out in accordance with the following steps:
(1) according to parts by weight, it fetches water 180 parts, 8 parts of arasaponin, 8 parts of general ginsenoside, 5 parts of glycerol, fourth It 5 parts of glycol, 2 parts of allantoin, 3 parts of EDETATE SODIUM, is added in kettle and is heated to 80 DEG C, 40min, mixed liquor A is made;
(2) 15 parts of isoflavones, 5 parts of Troxerutin, 10 parts of vitamin E, ceteareth -10 4 are taken Part, it 2 parts of cetostearyl alcohol, is added in oil cauldron, is heated to 80 DEG C, 40min, mixed liquid B is made;
(3) emulsion pot is vacuumized and its vacuum degree is made to maintain 0.06Pa, while opening emulsion pot heat button, to cream Change pot heating;
(4) mixed liquor A is slowly pumped into emulsion pot under vacuum conditions, constant temperature keeps the temperature in emulsion pot 85 ℃;
(5) mixed liquid B is slowly pumped into mixing speed in the emulsion pot of 20/min;Constant temperature keeps the temperature in emulsion pot Degree opens homogenizer button at 85 DEG C, and homogeneous stirs 8min under 10r/min mixing speed;Revolving speed is improved, 25r/min's 15min is stirred under mixing speed;
(6) cooling water is opened, and controls the speed of cooling water, is cooled down while stirring, by the temperature of emulsion pot in 45min It is reduced to 60 DEG C;
(7) sodium benzoate of 4 parts of hyaluronic acid, 1 part is taken, 10 parts of tranexamic acid, which is dissolved in 120 parts of water, obtains solution C; Solution C is slowly added into emulsion pot, vacuum buttons are then turned on, the vacuum degree in emulsion pot is made to be maintained at 0.06Pa;It stirs Mixing makes the temperature in emulsion pot be reduced to 55 DEG C;
(8) 5 parts of vitamin B2,10 parts of vitamin B5,5 parts of vitamin B6 are taken, is added in emulsion pot, and make cream The vacuum degree changed in pot is maintained at 0.06Pa;Mixed liquor is obtained after stirring 15min;
(9) mixed liquor prepared by step (8) is placed in sterilization container, is cooled to 25 DEG C, applies preservative film, seals up for safekeeping for 24 hours, To obtain the final product.
Embodiment 2
A kind of composition for repairing striae of pregnancy scar, is made of the raw material of following parts by weight: 20 parts of isoflavones, 10 parts of Troxerutin, 10 parts of arasaponin, 10 parts of general ginsenoside, 8 parts of vitamin B2,10 parts of vitamin B5,8 parts of vitamin B6,10 parts of vitamin E, 12 parts of tranexamic acid, 5 parts of glycerol, 2 parts of allantoin, 5 parts transparent Matter acid sodium, 1 part of sodium benzoate, 3 parts of EDETATE SODIUM, 4 parts of ceteareth -10,2 parts of cetostearyl alcohol, 250 parts of water, 5 parts of butanediol.
The preparation method of composition of above-mentioned treatment striae of pregnancy scar, carries out in accordance with the following steps:
(1) according to parts by weight, it fetches water 150 parts, 10 parts of arasaponin, 10 parts of general ginsenoside, 5 parts of glycerol, It 5 parts of butanediol, 2 parts of allantoin, 3 parts of EDETATE SODIUM, is added in kettle and is heated to 80 DEG C, 40min, mixed liquor A is made;
(2) 20 parts of isoflavones, 10 parts of Troxerutin, 10 parts of vitamin E, ceteareth -10 are taken It 4 parts, 2 parts of cetostearyl alcohol, is added in oil cauldron, is heated to 80 DEG C, 40min, mixed liquid B is made;
(3) emulsion pot is vacuumized and its vacuum degree is made to maintain 0.06Pa, while opening emulsion pot heat button, to cream Change pot heating;
(4) mixed liquor A is slowly pumped into emulsion pot under vacuum conditions, constant temperature keeps the temperature in emulsion pot 85 ℃;
(5) mixed liquid B is slowly pumped into mixing speed in the emulsion pot of 20/min;Constant temperature keeps the temperature in emulsion pot Degree opens homogenizer button at 85 DEG C, and homogeneous stirs 8min under 10r/min mixing speed;Revolving speed is improved, 25r/min's 15min is stirred under mixing speed;
(6) cooling water is opened, and controls the speed of cooling water, is cooled down while stirring, by the temperature of emulsion pot in 45min It is reduced to 60 DEG C;
(7) sodium benzoate of 4 parts of hyaluronic acid, 1 part is taken, 12 parts of tranexamic acid, which is dissolved in 100 parts of water, obtains solution C; Solution C is slowly added into emulsion pot, vacuum buttons are then turned on, the vacuum degree in emulsion pot is made to be maintained at 0.06Pa;It stirs Mixing makes the temperature in emulsion pot be reduced to 55 DEG C;
(8) 8 parts of vitamin B2,10 parts of vitamin B5,8 parts of vitamin B6 are taken, is added in emulsion pot, and make cream The vacuum degree changed in pot is maintained at 0.06Pa;Mixed liquor is obtained after stirring 15min;
(9) mixed liquor prepared by step (8) is placed in sterilization container, is cooled to 25 DEG C, applies preservative film, seals up for safekeeping for 24 hours, To obtain the final product.
Embodiment 3
A kind of composition for repairing striae of pregnancy scar, is made of the raw material of following parts by weight: 15 parts of isoflavones, 5 parts of Troxerutin, 8 parts of arasaponin, 8 parts of general ginsenoside, 5 parts of vitamin B2,10 parts of vitamin B5,5 Vitamin B6,10 parts of the vitamin E, 10 parts of tranexamic acid, 5 parts of glycerol, 2 parts of allantoin, 5 parts of hyaluronic acid of part Sodium, 1 part of sodium benzoate, 3 parts of EDETATE SODIUM, 3 parts of ceteareths -10,2 parts of cetostearyl alcohol, 200 parts of water, fourth two 5 parts of alcohol.
The preparation method of composition of above-mentioned treatment striae of pregnancy scar, carries out in accordance with the following steps:
(1) according to parts by weight, it fetches water 100 parts, 8 parts of arasaponin, 8 parts of general ginsenoside, 5 parts of glycerol, fourth It 5 parts of glycol, 2 parts of allantoin, 3 parts of EDETATE SODIUM, is added in kettle and is heated to 80 DEG C, 40min, mixed liquor A is made;
(2) 15 parts of isoflavones, 5 parts of Troxerutin, 10 parts of vitamin E, 3 parts of ceteareths-are taken 10,2 parts of cetostearyl alcohols, are added in oil cauldron, are heated to 80 DEG C, 40min, and mixed liquid B is made;
(3) emulsion pot is vacuumized and its vacuum degree is made to maintain 0.06Pa, while opening emulsion pot heat button, to cream Change pot heating;
(4) mixed liquor A is slowly pumped into emulsion pot under vacuum conditions, constant temperature keeps the temperature in emulsion pot 85 ℃;
(5) mixed liquid B is slowly pumped into mixing speed in the emulsion pot of 20/min;Constant temperature keeps the temperature in emulsion pot Degree opens homogenizer button at 85 DEG C, and homogeneous stirs 8min under 10r/min mixing speed;Revolving speed is improved, 25r/min's 15min is stirred under mixing speed;
(6) cooling water is opened, and controls the speed of cooling water, is cooled down while stirring, by the temperature of emulsion pot in 45min It is reduced to 60 DEG C;
(7) sodium benzoate of 4 parts of hyaluronic acid, 1 part is taken, 10 parts of tranexamic acid, which is dissolved in 100 parts of water, obtains solution C; Solution C is slowly added into emulsion pot, vacuum buttons are then turned on, the vacuum degree in emulsion pot is made to be maintained at 0.06Pa;It stirs Mixing makes the temperature in emulsion pot be reduced to 55 DEG C;
(8) 5 parts of vitamin B2,10 parts of vitamin B5,5 parts of vitamin B6 are taken, is added in emulsion pot, and make cream The vacuum degree changed in pot is maintained at 0.06Pa;Mixed liquor is obtained after stirring 15min;
(9) mixed liquor prepared by step (8) is placed in sterilization container, is cooled to 25 DEG C, applies preservative film, seals up for safekeeping for 24 hours, To obtain the final product.
Above-described embodiment 1~3 is tested, the following are experiment effects:
Selection has striae of pregnancy patient 120, is divided into 3 groups, the reparation striae of pregnancy composition that every group of embodiment obtains selects respectively It is tested with 40 volunteers, volunteer is the patient for having obvious striae of pregnancy postpartum, and striae of pregnancy frost of dispelling is smeared in affected part, daily 3-4 times, routine observation is as unchanged in 1 month striae of pregnancy phenomenon is used continuously, and it is invalid to be judged to, and stops treatment;Effective case connects Continuous medication 3 months, evaluate experimental result.
Effect judgment criteria is as follows:
Effective: striae of pregnancy is thin out and 50% or more range shorter;
Effective: striae of pregnancy is thin out and 20% or more range shorter;
Invalid: striae of pregnancy is not reduced without thin out and range.
Total effective rate %=(effective number of cases+effective number of cases)/total number of cases × 100%.
Statistical result is as shown in table 1:
Embodiment Total number of cases Effective number of cases Effective number of cases Invalid number of cases Total effective rate/%
1 40 26 10 4 90
2 40 24 9 7 82.5
3 40 25 9 6 85
It is total 120 74 28 17 85
The experimental results showed that the composition total effective rate that the present invention repairs striae of pregnancy is greater than 80%, and embodiment 1 is best Component proportion repairs striae of pregnancy and works well.
The above-described embodiments are merely illustrative of preferred embodiments of the present invention, not to structure of the invention Think and range is defined.Without departing from the design concept of the invention, ordinary people in the field is to technology of the invention The all variations and modifications that scheme is made, should all drop into protection scope of the present invention, the claimed technology contents of the present invention, It is all described in the claims.

Claims (1)

1. a kind of composition for repairing striae of pregnancy scar, it is characterised in that: including following composition according to parts by weight, soybean is different 10-20 parts of flavones, 2-10 parts of Troxerutin, 5-15 parts of arasaponin, 3-8 parts of ginsenoside, 5-15 parts of vitamin B2, dimension Raw 5-10 parts of element B5,3-10 parts of vitamin B6,3-15 parts of vitamin E, 3-15 parts of tranexamic acid, 5-20 parts of glycerol, allantoin 5-10 parts, 5-10 parts of Sodium Hyaluronate, 0.1-1 parts of sodium benzoate, 10-20 parts of water phase auxiliary agent, oily 10-20 parts of phase auxiliary agent.
CN201910885081.0A 2019-09-19 2019-09-19 A kind of composition for repairing striae of pregnancy scar Pending CN110464687A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514082A (en) * 2020-05-14 2020-08-11 深圳爱思得美容科技有限公司 Striae gravidarum repair composition and application method thereof

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Publication number Priority date Publication date Assignee Title
US20040146539A1 (en) * 2003-01-24 2004-07-29 Gupta Shyam K. Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
CN104306438A (en) * 2014-10-22 2015-01-28 谢钦 Liquid with effects of clearing and activating the channels and collaterals and preparation method and application thereof
CN108030754A (en) * 2017-12-29 2018-05-15 吕玲 A kind of face cream for eliminating striae of pregnancy and desalinating scar and preparation method thereof
US20210137819A1 (en) * 2017-07-31 2021-05-13 Ho Seog LEE Composition for preventing or treating scars

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040146539A1 (en) * 2003-01-24 2004-07-29 Gupta Shyam K. Topical Nutraceutical Compositions with Selective Body Slimming and Tone Firming Antiaging Benefits
CN104306438A (en) * 2014-10-22 2015-01-28 谢钦 Liquid with effects of clearing and activating the channels and collaterals and preparation method and application thereof
US20210137819A1 (en) * 2017-07-31 2021-05-13 Ho Seog LEE Composition for preventing or treating scars
CN108030754A (en) * 2017-12-29 2018-05-15 吕玲 A kind of face cream for eliminating striae of pregnancy and desalinating scar and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111514082A (en) * 2020-05-14 2020-08-11 深圳爱思得美容科技有限公司 Striae gravidarum repair composition and application method thereof

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