CN110459113A - A kind of organ perfusion's teaching and training system - Google Patents
A kind of organ perfusion's teaching and training system Download PDFInfo
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- CN110459113A CN110459113A CN201910822478.5A CN201910822478A CN110459113A CN 110459113 A CN110459113 A CN 110459113A CN 201910822478 A CN201910822478 A CN 201910822478A CN 110459113 A CN110459113 A CN 110459113A
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- 210000000056 organ Anatomy 0.000 title claims abstract description 196
- 230000010412 perfusion Effects 0.000 title claims abstract description 54
- 238000012549 training Methods 0.000 title claims abstract description 27
- 239000007788 liquid Substances 0.000 claims abstract description 80
- 230000037452 priming Effects 0.000 claims abstract description 29
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 22
- 238000012423 maintenance Methods 0.000 claims abstract description 20
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 31
- 210000000709 aorta Anatomy 0.000 claims description 20
- 239000001301 oxygen Substances 0.000 claims description 20
- 229910052760 oxygen Inorganic materials 0.000 claims description 20
- 208000019790 abdominal distention Diseases 0.000 claims description 17
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 17
- 238000002627 tracheal intubation Methods 0.000 claims description 17
- 210000003462 vein Anatomy 0.000 claims description 13
- 238000013459 approach Methods 0.000 claims description 12
- 210000004185 liver Anatomy 0.000 claims description 12
- 210000000702 aorta abdominal Anatomy 0.000 claims description 11
- 230000001079 digestive effect Effects 0.000 claims description 11
- 238000012544 monitoring process Methods 0.000 claims description 10
- 210000001015 abdomen Anatomy 0.000 claims description 9
- 238000005286 illumination Methods 0.000 claims description 9
- 210000000941 bile Anatomy 0.000 claims description 8
- 238000001839 endoscopy Methods 0.000 claims description 8
- 210000003238 esophagus Anatomy 0.000 claims description 8
- 210000000115 thoracic cavity Anatomy 0.000 claims description 8
- 210000001147 pulmonary artery Anatomy 0.000 claims description 7
- 210000000664 rectum Anatomy 0.000 claims description 7
- 230000000740 bleeding effect Effects 0.000 claims description 6
- 230000002159 abnormal effect Effects 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 238000002347 injection Methods 0.000 claims description 5
- 239000007924 injection Substances 0.000 claims description 5
- 238000004088 simulation Methods 0.000 claims description 5
- 238000001356 surgical procedure Methods 0.000 claims description 5
- 206010044565 Tremor Diseases 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 210000004258 portal system Anatomy 0.000 claims description 3
- 239000002699 waste material Substances 0.000 claims description 3
- 210000001367 artery Anatomy 0.000 claims description 2
- 238000012545 processing Methods 0.000 claims description 2
- 238000011158 quantitative evaluation Methods 0.000 claims description 2
- 230000002792 vascular Effects 0.000 description 32
- 210000003240 portal vein Anatomy 0.000 description 13
- 210000004369 blood Anatomy 0.000 description 12
- 239000008280 blood Substances 0.000 description 12
- 238000010992 reflux Methods 0.000 description 10
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- 230000003187 abdominal effect Effects 0.000 description 7
- 210000003484 anatomy Anatomy 0.000 description 7
- 239000012530 fluid Substances 0.000 description 7
- 210000001758 mesenteric vein Anatomy 0.000 description 7
- 210000000952 spleen Anatomy 0.000 description 7
- 210000002700 urine Anatomy 0.000 description 7
- 239000000306 component Substances 0.000 description 6
- 239000008358 core component Substances 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 210000000683 abdominal cavity Anatomy 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 210000000955 splenic vein Anatomy 0.000 description 5
- 210000001557 animal structure Anatomy 0.000 description 4
- 238000000338 in vitro Methods 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 210000001363 mesenteric artery superior Anatomy 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 210000000038 chest Anatomy 0.000 description 3
- 239000012535 impurity Substances 0.000 description 3
- 238000004321 preservation Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
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- 229910002027 silica gel Inorganic materials 0.000 description 3
- 235000004443 Ricinus communis Nutrition 0.000 description 2
- 208000007536 Thrombosis Diseases 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
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- 239000007789 gas Substances 0.000 description 2
- 210000002767 hepatic artery Anatomy 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 238000007912 intraperitoneal administration Methods 0.000 description 2
- 210000004249 mesenteric artery inferior Anatomy 0.000 description 2
- 239000000082 organ preservation Substances 0.000 description 2
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- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 208000005646 Pneumoperitoneum Diseases 0.000 description 1
- 240000000528 Ricinus communis Species 0.000 description 1
- 210000000436 anus Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
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- 238000002474 experimental method Methods 0.000 description 1
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- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
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Classifications
-
- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/285—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine for injections, endoscopy, bronchoscopy, sigmoidscopy, insertion of contraceptive devices or enemas
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- Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Computational Mathematics (AREA)
- Mathematical Optimization (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Algebra (AREA)
- Radiology & Medical Imaging (AREA)
- Pulmonology (AREA)
- Mathematical Analysis (AREA)
- General Health & Medical Sciences (AREA)
- Mathematical Physics (AREA)
- Pure & Applied Mathematics (AREA)
- Business, Economics & Management (AREA)
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Abstract
The present invention proposes a kind of organ perfusion's teaching and training system, comprising: organ storehouse (2): for accommodating organism organ (1) and collateral blood vessels；Containing liquid chamber (3): it is located at below the organ storehouse (2), for storing circumfusion liquid；Temperature maintenance device (4): for maintaining the temperature of organism organ (1)；Priming line (8): the collateral blood vessels of connection containing liquid chamber (3) and organism organ (1), under the driving of pump (7), pressurizeed to the organism organ (1) and collateral blood vessels, circumfusion；Pump (7): it pressurizes, is pressurizeed to the organism organ (1) and collateral blood vessels, circumfusion to circulation line (8)；Display (35) is recorded a video for display operation；Pedestal (61), is used to support, moves, goes up and down single unit system；Single or multiple organism organs (1) can be perfused in organ perfusion's save set simultaneously.Multiple organs can be perfused in the present invention simultaneously.
Description
Technical field
The present invention relates to a kind of Medical teaching training systems, more particularly, to a kind of organ perfusion's teaching and training system.
Background technique
In medicine training process, in order to allow Surgical laparoscope, natural cavity scope, operating robot, internal medicine digestion in
The training effects such as mirror are truer, need to be operated training using big animal.But with the progress of social civilization, medicine
The development of ethics is established the factors such as the expensive cost of big animal surgery room, the expensive expense of the big zoopery of single in addition, is limited
It has made and has carried out operative training using big animal.Medicine training at present mostly using buying in the market, edible big animal organ
It is used for training, but these organs do not have great-hearted in vitro dead organ often, and are single organs, not only lack and live
Power, organ with it is larger in body existing state difference, and can not accurate simulation bleeding, intestines can not wriggle, and liver can not generate
Bile, kidney can not generate urine, and heart can not beat, therefore it is poor to simulate effect；And the whole anatomical structure of single organ
It has been be destroyed that, Systematic anatomy training can not be carried out, result of training is poor.The virtual reality training device occurred in recent years,
The defects of there are many defects, such as lack anatomical variation, and surgical procedure lacks authenticity, and price is high.
The present apparatus can be used for big animal organ's machine perfusion and save, in animal welfare and the increasingly strict situation of protection system
Under, using the organ and blood of the pig obtained from slaughterhouse, connection the machine is tested.The examination of ethics is not only avoided, and
And the period of laboratory application and ethics application is avoided, experimental cost is more cheap, and organ number is more sufficient, avoids operation skill
The artificial disturbing factor such as art, and avoid the expensive cost for establishing big Animal Lab., be next step scale, high efficiency,
Experimental period is greatly shortened, experimental cost is greatly reduced, reduces disturbing factor creation necessary condition.
Chinese invention patent application 201580002264.3 discloses a kind of simulation human body device, comprising: from animal
Organ, with bio-tissue and the blood vessel extended from the bio-tissue；Blood reservoir accumulates the oriented blood
The blood of pipe conveying；Pipe connects the blood vessel and the blood reservoir；Pumping section is set to the midway of the pipe and from institute
It states blood reservoir and conveys blood to the blood vessel；And incorporating section, the organ is stored, Xiang Suoshu conveyed compares room temperature
The steam of high temperature humidifies the organ, and the organ is set as to 20-50 DEG C of temperature.
The simulation human body device basic structure of the prior art does not include oxygenator and filter bolt device, and is used single
Organ cannot achieve multiple organ while be perfused.And the prior art is accomplished that unidirectional perfusion, and human organ is to need blood
Liquid reflux cycle.As it can be seen that the organ machine perfusion device of the prior art is complicated, heavy and be not carried out multiple organ preservation,
Also it cannot achieve multiple organ preservation.
Summary of the invention
In order to realize clinical multiple organ Plantlet in vitro simultaneously, it is necessary to establish using abdominal aorta or aorta pectoralis as the more of core
Organ perfusion's system.For simplified operation, the device of the invention passes through abdominal aortic or chest active by single pump and priming line
Vein system unites while multiple organs or single organ is perfused, and wherein liver portal vein relies on without intubation and passes through enteron aisle arterial system
And the circumfusion liquid of arteria linenalis carries out reflux perfusion；Multiple thoracic organs can be perfused simultaneously by aorta pectoralis system, wherein
Pulmonary artery is irrigated without intubation by the circumfusion liquid of the right heart.In the case where saving multiple organ, it is only necessary to single to insert
Pipe, hence it is evident that simplify, this is entirely different basic principle with the prior art.
The present invention discloses a kind of organ perfusion's teaching and training system, comprising:
Organ storehouse: for accommodating organism organ and collateral blood vessels；
Containing liquid chamber: it is located at below the organ storehouse, for storing circumfusion liquid；
Temperature maintenance device: for maintaining the temperature of organism organ；
Priming line: the collateral blood vessels of connection containing liquid chamber and organism organ, under the driving of pump, to the organism device
Official and collateral blood vessels pressurize, circumfusion；
Pump: it pressurizes, is pressurizeed to the organism organ and collateral blood vessels, circumfusion to circulation line；
Display is used for display operation image；
Pedestal is used to support, moves and goes up and down single unit system；
Organ perfusion's save set can the aorta system to organism pressurize, circumfusion, Neng Goutong
When single or multiple organism organs are perfused.
Further, multiple abdomen organs can be perfused simultaneously by abdominal aorta system in organ perfusion's save set,
Wherein liver portal vein is irrigated without intubation by the circumfusion liquid that portalsystem flows back.
Further, multiple thoracic organs can be perfused simultaneously by aorta pectoralis system in organ perfusion's save set,
Wherein pulmonary artery is irrigated without intubation by the circumfusion liquid of the right heart.
Further, it the system further include: oxygenator: is closed for circumfusion liquid to be continued oxygen；Filter bolt device: it was used for
Filter circumfusion liquid.
Further, the system further include: upper cover: for closing organ storehouse and temperature maintenance device；Lifting column, it is described
Lifting column can adjust the height of operating platform, wherein the operating platform support housing and upper cover；Display bracket, for branch
Support display.
Further, the system further include: abdominal distention, abdominal distention is arranged on upper lid, for simulating human body abdomen
Portion is swelled, and there are mis instruments or scope entrance, alimentary canal to operate approach, mis instruments or scope entrance on the abdominal distention
Enter for needle holder being applied to surgery Minimally instrument, alimentary canal operates approach and enters for digestive endoscopy soft lens.
Further, the alimentary canal operation approach includes esophagus entrance and rectum entrance, and esophagus entrance is used for upper digestive tract
Endoscope and image processing device enters, and rectum entrance is for collecting discharged waste or entering for digestive endoscope device.
Further, it is provided with intraoral illumination lamp in the abdominal distention, the opposite abdominal distention is provided with micro- on upper lid
Type exhaust fan.
Further, mis instruments Universal arm fixing seat is provided with around upper cover, for fixing gimbals.
Further, the gimbals include: camera shooting bar fixation hole, camera shooting bar fixed handle and universal structure locking hand
Handle.
Further, the system further include: temperature sensors, for monitor the circumfusion liquid in containing liquid chamber,
The temperature of organism organ 1；Flow sensor, for monitoring the flow of circumfusion liquid in priming line；Pressure sensor is used
In the pressure of the circumfusion liquid in monitoring priming line.
Further, the system further include: tablet computer host, tablet computer host) include essential information data
Library records operator's essential information；With operation points-scoring system, following parameter can be collected and carry out quantitative evaluation: amount of bleeding, hand
Art time, degree of trembling and degree-of-difficulty factor index；Video recording and storage system, to record operation video, and can play back；Network connection
Function is connected to the network and is monitored to realization device；It can be in control panel and display information displayed on screen.
Further, the system further include: controller, the controller are configured as collecting temperature sensor, flow
The signal of sensor, pressure sensor after handling by analysis, can carry out control as follows:
The revolving speed of control pump prevents injection pressure or Traffic Anomaly, avoids or Traffic Anomaly, even results in damage organism
Organ；
Control oxygenator heat cycles pump and temperature maintenance device maintain the temperature of organism organ and circulation line,
Middle oxygenator heat cycles pump carries out circulating-heating to oxygenator for extracting out warm water in water bath；
The height for controlling lifting column adapts to different height operators；The brightness of intraoral illumination lamp is controlled, is provided most for training operation
Good brightness；
Control priming line clamps down on the folding condition that valve adjusts priming line in time；Pass through when device is abnormal situation
Alarm device carries out timely alarm；
The state of control panel and display screen display controller, and relevant parameter can be manually adjusted.
Further, there is diaphram suspended structure inside the organ storehouse, for hanging diaphram, the normal of organ is closed on simulation
Anatomical position.
Further, it is provided with minimally invasive equipment compartment, oxygen cylinder, bile on the pedestal and collects metering device and/or urine receipts
Collect metering device.
Compared with the prior art of Chinese patent application 201580002264.3, the present invention and there is following difference: 1) base
This structure is different, and the device of the invention not only includes: organ and its connection blood vessel, pumping section, pipe, heating apparatus, organ storehouse；Also wrap
Include oxygenator, filter bolt device etc.；2) pipeline structure of the device of the invention is different from Chinese patent application 201580002264.3, this
Invention is according to single pump and single vessel intubation, and by abdominal aorta or aorta pectoralis system, while it is more that abdominal cavity or thoracic cavity is perfused
A organ, liver portal vein rely on enteron aisle and spleen reflux perfusion liquid are irrigated without intubation；The present apparatus can be by chest actively
Vein system unites while multiple thoracic organs is perfused, and wherein pulmonary artery is irrigated without intubation by the circumfusion liquid of the right heart；3)
The present invention realizes blood backflow circulation, and Chinese patent application 201580002264.3 is only unidirectional perfusion, does not refer to circulation
Perfusion；
In addition, beneficial effects of the present invention further include:
The device of the invention be suitable for the minimally invasive training of medicine (laparoscope, natural cavity scope, operating robot, in digestion
Mirror etc.), using the easy structure of single-intubation aorta system circulation perfusion multiple organ, the big animal device discarded using slaughterhouse
Official, Perfusion preservation in vitro, using blood or cell-free type circumfusion liquid, circumfusion supplements energy substrate and oxygen carrying, dimension
Organ vitality is held, and does not destroy the anatomical structure of abdominal cavity or thoracic organs, doctor is helped to grasp routine operation or minimally invasive skill
Art basic operation.While to the full extent close to the effect of big zoopery, it is substantially reduced with cost, ethics is avoided to ask
Topic, and there are anatomical variations, keep complete anatomical structure, and organ maintains vigour, and has the clear superiorities such as bleeding after damage.
Detailed description of the invention
Fig. 1 is the basic structure floor map of organ perfusion's save set of present system.
Fig. 2 is the stereoscopic schematic diagram of organ perfusion's save set of present system.
Fig. 3 is the schematic illustration of organ perfusion's save set of present system.
Fig. 4 is the organ storehouse top view of organ perfusion's save set of present system.
Fig. 5 is the core component top view of organ perfusion's save set of present system.
Fig. 6 is the core component side view of organ perfusion's save set of present system.
Fig. 7 is the core component explosive view of organ perfusion's save set of present system.
Fig. 8 is the oxygenator and filter bolt device assembly overall appearance of present system.
Fig. 9 is the oxygenator and filter bolt device assembly sectional view of present system.
Figure 10 is present system entirety right perspective view.
Figure 11 is present system entirety left perspective view.
Figure 12 is present system overall top view.
Figure 13 is present system entirety right view.
Figure 14 is the whole rearview of present system.
Figure 15 is that the upper cover of present system opens wide whole right perspective view.
Figure 16 is that the upper cover of present system opens wide whole left perspective view.
Figure 17 is that the upper cover of present system opens wide overall top view.
Figure 18 is the mis instruments entrance basic structure of present system.
Figure 19 is the digestive endoscopy entrance basic structure of present system.
Figure 20 is the instrument extension box basic structure of present system.
Figure 21 is the camera shooting bar gimbals schematic diagram of present system
Figure 22 is the bile of present system, urine collecting schematic diagram.
Figure 23 is present system rear portion primary structure schematic diagram.
Figure 24 is the electronic control system schematic diagram of present system.
Appended drawing reference
1- organism organ, 2- organ storehouse, 3- containing liquid chamber, 4- temperature maintenance device, 5- oxygenator, 6- filter bolt device, and 7- is pumped,
8- priming line, 9- vascular catheterization, 10- water bath, 11- esophagus entrance, 12- alimentary canal operate approach, 13- rectum entrance, 14-
Diaphram suspension, 16- bile collect metering device, 17- urine collecting metering device, and 18- images bar fixation hole, and it is solid that 19- images bar
Determine handle, 20- universal structure lock handle, 21- power pack, 22- diaphram, the proximal end 23- Abdominal aortic crossclamping ligature, 24- abdomen
Chamber is dry, 25- arteria linenalis, 26- superior mesenteric artery, the distal end 27- abdominal aortic cannulation ligature, 28- abdominal aorta, on 29- liver
Inferior caval vein, 30- liver, 31- proper hepatic artery, 32- splenic vein, superior mesenteric vein and portal vein meet, 33- kidney are dynamic
Arteries and veins, 34- infrahepatic vena cava, 35- display, 36- display bracket, 37- abdominal distention, 38- mis instruments or scope entrance,
38-1 screw-cap, 38-2 silica gel sealing piece, 38-3 spiral pedestal, 39- tablet computer host, 40- casing, the miniature row of 41-
Fan, 42- temperature controller, 43- lifting column, 44- handle, 45- instrument extension box, 45-1 instrument jack, 45-2 hook, 45-3 device
Tool box main body, 46- oxygen cylinder, 47- electric knife storehouse, the minimally invasive equipment compartment of 48-, 49- castor, 50- oxygenator and filter bolt device storehouse, 51- oxygen
Throughput adjusts table, 52- heater storehouse, 53- mis instruments Universal arm fixing seat, 54- oxygenator and filter bolt device shell, on 55-
Lid, 56- intraoral illumination lamp, 57- oxygen bottle supporter, 58- organ storehouse shelf, 59- organ storehouse fixed knob, 60- return line, 61-
Pedestal, 62- upper cover hinge, 63- oxygenator heat cycles interface, 64- vascular catheterization interconnecting piece, 65- oxygenator heater, 66-
Flow sensor, 67- controller, 68- temperature sensor, 69- pressure sensor, 70- priming line clamp down on valve, 71- oxygenator
Heat cycles pump, 72- spleen, 73- stomach, 74- enteron aisle, 75- kidney, 76- portal vein, 77- splenic vein, 78- superior mesenteric vein,
79- inferior mesenteric vein, 80- right gastroepiploic vein, 81- inferior mesenteric artery, 82- low-voltage dc power supply, 83- control panel and
Display screen, 84- alarm device.
Specific embodiment
Embodiments of the present invention are described with reference to the accompanying drawings, wherein identical component is presented with like reference characters.
In the absence of conflict, the technical characteristic in following embodiment and embodiment can be combined with each other.
The core component of system of the invention is the machine perfusion save set for organism organ, referring to Fig. 1-
Fig. 9 describes the machine perfusion save set.
As shown in Figure 1-3, the device of the invention is used for organism organ 1, organism organ 1 is including organism organ and certainly
The attached blood vessel of the organism organ, organism organ 1 can be organ cluster or individual organ.
The device of the invention saves organism organ 1 for machine perfusion, comprising: organ storehouse 2, containing liquid chamber 3, temperature maintain
Device 4, oxygenator 5, filter bolt device 6, pump 7 and priming line 8.Preferably, the vascular catheterization 9 including 8 end of priming line.
Organ storehouse 2 is for accommodating organism organ 1 and the blood vessel attached from the organism organ；Containing liquid chamber 3 is located at device
2 lower part of official storehouse, for collecting the circumfusion liquid to flow back from organism organ vein end；Temperature maintenance device 4 is used for maintainer
Official storehouse 2, containing liquid chamber 3 and device bulk temperature；For oxygenator 5 for closing circumfusion liquid oxygen, oxygenator 5 is connected with oxygen cylinder
46；Filter the impurity such as thrombus, the bubble that bolt device 6 is used in filtration cycle perfusion liquid；Power maintenance, pressurization is perfused for device in pump 7
Perfusion and circumfusion；Priming line 8 is for connecting each critical component；Vascular catheterization 9 is located at the end of priming line 8, connection
The aorta system of organism organ 1 carries out enhancing perfusion and circumfusion.Preferably, vascular catheterization 9 is in aorta system
Different branch's corresponding positions, have corresponding side opening, internal diameter is matching, and corresponding organ can more accurately be perfused.Blood vessel is inserted
Pipe 9 also can have multiple branches.
Portal vein 76 relies on the reflux perfusion liquid from the perfusion of arteria linenalis 25 to spleen 72, superior mesenteric artery without intubation
26 perfusions are filled after splenic vein, superior mesenteric vein and portal vein meet 32 converge to the reflux perfusion liquid of enteron aisle 74
Note.
As shown in Fig. 2, present apparatus basic functional principle is as follows: organism organ 1 is placed in organ storehouse 2, by organ storehouse 2
The temperature maintenance device 4 in outside maintains temperature (organ storehouse 2 is placed in temperature maintenance device 4), circumfusion liquid (including blood or
Noncellular circulation fluid etc.) it flows back and is stored in containing liquid chamber 3, containing liquid chamber 3 is located at 2 lower section of organ storehouse.The organ storehouse in organ storehouse 2
There is through-hole on shelf 58, so that organ storehouse 2 and containing liquid chamber 3 are that physics communicates, flowed out convenient for perfusion liquid from organism organ 1
Afterwards, the containing liquid chamber 3 of organ storehouse lower layer is flowed back into.(as shown in Figure 6, Figure 7) in one embodiment, temperature maintenance device 4 select
With the form of water bath 10, the organ storehouse 2 being immersed in water bath 10 can not only be directly heated, and have oxygenator heating
Warm water in water bath 10 extract by circulating pump 71 (setting water bath 10 either internally or externally), is carried out circulation to oxygenator 5 and is added
Heat improves heating efficiency.In another embodiment, temperature maintenance device 4 selects compressor, ice cube or ultralow temperature agent etc.
Form maintains the low temperature of containing liquid chamber 3, organ storehouse 2 and its interior organism organ 1.
Under the driving of pump 7, the circumfusion liquid in containing liquid chamber 3 enters filter bolt device 6, filters out impurity and gas therein
Bubble；Then oxygen conjunction is carried out by oxygenator 5；Again by circulation line 8, vascular catheterization 9, into the organism device in organ storehouse 2
Then the aorta system of official 1 is irrigated multiple organs using the different branches of aorta simultaneously；Finally, circumfusion
Liquid etc. is flowed out by the vein end of organism organ 1, is collected reflux and is concentrated on containing liquid chamber 3, and so on forms circumfusion.
Circular order is followed successively by the filter bolt device 6-of 1-containing liquid chamber of organism organ 3-in organ storehouse 2 and pumps 7-oxygenators
Organism organ 1 in 5-priming line, 8 (vascular catheterization 9)-organ storehouse 2.Priming line 8 connects each main component.
Multiple organs are perfused simultaneously by abdominal aortic or aorta pectoralis system in organ save set of the invention, wherein
Liver portal vein 76 is irrigated without intubation by the circumfusion liquid that portalsystem flows back.Wherein pulmonary artery is without inserting
Pipe, is irrigated by the circumfusion liquid of the right heart.
Optionally, vascular catheterization 9 is located at 8 end of priming line, connects the collateral blood vessels of organism organ 1, is irrigated.
Optionally, different branch corresponding positions of the vascular catheterization 9 in aorta system, have corresponding side opening, internal diameter with
Matching, corresponding organ can more accurately be perfused.
As shown in Figure 1-3, when using the present apparatus, firstly, organism organ 1 and its collateral blood vessels are placed on organ storehouse 2
Interior, all organs are arranged according to normal anatomical structures.Then, the both ends of abdominal aorta 28 are respectively by proximal end Abdominal aortic crossclamping knot
Binding 23, distal end Abdominal aortic crossclamping ligature 27 ligature, circulation line 8 (optionally, end connects vascular catheterization 9) insertion abdomen
Ligated line is fixed after aorta 28.Circumfusion liquid is driven by pump 7 and pressurizes, and by circulation line 8, (optionally, end is connected
Vascular catheterization 9) injection abdominal aorta 28, each organ is then perfused by abdominal aorta branch.Wherein, by the arteria renalis 33 to double
Side kidney 75 is irrigated；Arterial perfusion is carried out to liver 30 by 24 branch's proper hepatic artery 31 of coeliac trunk；And pass through abdominal cavity
Dry 24 branch's arteria linenalis 25 are irrigated spleen 72；By superior mesenteric artery 26, inferior mesenteric artery 81 to enteron aisle 74 into
Row arterial perfusion；The venous return superior mesenteric vein 78 and inferior mesenteric vein 79 of enteron aisle 74, the venous return spleen of spleen 72
Vein 77, the venous return right gastroepiploic vein 80 of stomach 73, jointly in splenic vein, superior mesenteric vein and portal vein meet 32
Converge, liver is irrigated commonly through portal vein 76, therefore perfusion can be realized without intubation in portal vein 76.The present apparatus is only
Abdominal aorta 28 and its branch are perfused by single pipe, the perfusion to full abdominal viscera can be completed.All circumfusion liquid
Organ storehouse 2 and containing liquid chamber 3 are flowed back by the liver superior and inferior vena cava 29 and infrahepatic vena cava 34 of inferior caval vein system, is then existed
Under the driving of pump 7, the circumfusion liquid in containing liquid chamber 3 enters filter bolt device 6, filters out impurity and bubble therein；Then pass through
Oxygenator 5 carries out oxygen conjunction；Again by circulation line 8 (optionally, end connects vascular catheterization 9), the biology into organ storehouse 2
Then the aorta system of body organ 1 is irrigated multiple organs using the different branches of aorta simultaneously, so recycles past
It is multiple；
Multiple thoracic organs can be perfused simultaneously by aorta pectoralis system in the present apparatus, and wherein pulmonary artery passes through without intubation
The circumfusion liquid of the right heart is irrigated.
Optionally, vascular catheterization 9 is located at 8 end of priming line, connects the collateral blood vessels of organism organ 1, is irrigated.
Optionally, different branch corresponding positions of the vascular catheterization 9 in aorta system, have corresponding side opening, internal diameter with
Matching, corresponding organ can more accurately be perfused.
Optionally, the device of the invention restores organ vitality with the animal organs such as pig or sheep, external machine perfusion, maximum
Degree simulates human organ, carries out medicine training.
Optionally, the device of the invention can be used for external machine perfusion preservation human organ, saves, plays for multiple organ
The effect of giving mutual protection of its key saves while repairing, assessing organ vitality.
Organ storehouse 2, containing liquid chamber 3, temperature maintenance device 4, oxygenator 5 and filter bolt device 6 are further refined referring to Fig. 4-9
The structure and principle of component.As shown in figure 4,2 bottom of organ storehouse has organ storehouse shelf 58, several holes are provided with, the storage with lower part
(see Fig. 2) is communicated in liquid storehouse 3, is back to containing liquid chamber 3 convenient for perfusion circulation fluid.It is provided with return line 60 on the inside of organ storehouse 2, flows back
Lead to 60 one end of pipeline containing liquid chamber 3, and the other end connects circulation line 8.Preferably, the bottom surface of containing liquid chamber 3 is inclined, towards return
It is tilted at 60 access of flow tube road, convenient for maintaining higher liquid level height, is not only convenient for collecting circulation fluid, and return line can be prevented
60 sucking air.
The outer wall of water bath 10 is provided with oxygenator heat cycles interface 63, by oxygenator heat cycles pump 71 for taking out
The warm water to absorb water in bath cabinet 10, heats circumfusion liquid by oxygenator 5.Oxygenator heat cycles interface 63 and organ
Storehouse 2 is not communicated with, and is communicated with water bath 10 (being explained in detail below).
Be provided on the side wall in organ storehouse 2 diaphram suspension 14, for hanging diaphram 22 (see Fig. 1), diaphram suspension 14 for from
Multiple diaphram suspensions 14 can be set in the inwardly projecting protrusion of the inner wall in organ storehouse 2.Diaphram hook 14 is used for organism organ
1 diaphragm segment is fixed and is hung, and utmostly restores liver in intraperitoneal anatomical position.
As shown in Figure 5-Figure 7, the inventive system comprises: organ storehouse 2, water bath 10 are (optional as temperature maintenance device 4
Mode), pump 7, oxygenator 5, filter bolt device 6, return line 60, vascular catheterization interconnecting piece 64 and vascular catheterization 9.Wherein, intrusion pipe
The reflux end on road 8 connects return line 60, perfusion end connection vascular catheterization interconnecting piece 64 and vascular catheterization 9, among priming line 8
The components such as connection pump 7, oxygenator 5 and filter bolt device 6.Organism organ 1 is placed on the organ storehouse shelf 58 in organ storehouse 2, and one
It rises and immerses the maintenance body temperature environment of water bath 10, diaphram hook 14 is for fixing and hanging the diaphragm segment of organism organ 1, most
Big degree restores intraperitoneal anatomical position.Optionally, the organ shelf 58 in organ storehouse 2 can be made of metal, as electric knife
Negative plate, to use electric knife.
Circumfusion liquid pump 7 pressurised driving under, by vascular catheterization 9 enter organism organ 1 abdominal aorta or
Aorta pectoralis system, while the multiple organs in abdominal cavity or thoracic cavity are perfused, portal vein 76 is relied on and is perfused from arteria linenalis 25 without intubation
To the reflux perfusion liquid of spleen 72, superior mesenteric artery 26 is perfused to the reflux perfusion liquid of enteron aisle 74, on splenic vein, mesenterium
Vein is irrigated after converging with portal vein meet 32.Pulmonary artery is filled without intubation by the circumfusion liquid of the right heart
Note.Thereafter circumfusion liquid is flowed out by the inferior caval vein of organism organ 1, is concentrated by the porous structure of organ storehouse shelf 58
It is back to the containing liquid chamber 3 of 2 lower part of organ storehouse；Thereafter under the driving of pump 7, the circulation fluid in containing liquid chamber 3 passes through return line 60
It is extracted flow direction filter bolt device 6, filters out the thrombus and aeroembolism mixed in circulation fluid；Then the outlet through filtering bolt device 6 passes through filling
Pipeline 8 is infused by pump 7, enters oxygenator 5 thereafter by priming line 8, oxygen conjunction is carried out to circulation fluid；Going out by oxygenator 5 again
Mouth enters vascular catheterization interconnecting piece 64, enters vascular catheterization 9 using vascular catheterization interconnecting piece 64, and so on completes circulation filling
Note process.
As shown in Fig. 6-Fig. 9, organ storehouse 2 and containing liquid chamber 3 are placed in temperature maintenance device 4, and temperature maintenance device 4 includes
Water bath 10 and temperature controller 42.Temperature is maintained through two kinds of approach, the first approach, and the interior installation of water bath 10 is warm water
Directly organ storehouse 2, containing liquid chamber 3 and organism organ 1 are heated.Second of approach pumps 71 by setting oxygenator heat cycles
Warm water in water bath 10 is aspirated by oxygenator heat cycles interface 63, into oxygenator heater 65, oxygenator adds
Hot device 65 is located at 5 lower section of oxygenator, to heat the circulation fluid in oxygenator 5.
Temperature controller 42 can control the temperature of water bath 10, and temperature controller 42 can control electric heater unit heating
Water in water bath 10.
Oxygenator 5 and filter bolt device 6 are centrally located in oxygenator and filter bolt device shell 54,8 rule of respective cycle pipeline
It is distributed in shell 54, is convenient for Fast Installation and replacement；Optionally, in addition to pump 7, organ storehouse 2, containing liquid chamber 3, oxygenator 5, filter
The components such as bolt device 6, priming line 8 and vascular catheterization 9, return line 60 can be convenient for quick-replaceable to be disposable.
Referring again to such as Fig. 6, temperature sensor 68 is arranged inside organ storehouse 2, for monitoring the organism in organ storehouse 2
The temperature of organ 1.Flow sensor 66 is arranged on return line 60 and vascular catheterization interconnecting piece 64, flows through reflux for monitoring
The flow of 64 circumfusion liquid of pipeline 60 and vascular catheterization interconnecting piece.Pressure sensor 69 is arranged in vascular catheterization interconnecting piece 64
On, wherein 64 end of vascular catheterization interconnecting piece is connected with vascular catheterization 9.Pressure sensor 69 is for monitoring vascular catheterization interconnecting piece
Pressure at 64, that is, monitoring will be transported to the pressure of the circumfusion liquid of vascular catheterization 9.
Referring again to FIGS. 6, organ perfusion's save set of the invention further includes that priming line clamps down on valve 70, setting is being filled
It infuses on pipeline 8, is shown provided in figure near 7 input terminals of pump, priming line, which clamps down on the closing of valve 70, can quickly stop being perfused
The circumfusion of pipeline 8 damages organism organ 1 when avoiding the occurrence of exception.
System of the invention is described referring to Figure 10-Figure 24.It is (outer that system of the invention is mainly used for the minimally invasive training of medicine
Section's laparoscope, natural cavity scope, operating robot, internal medicine digestive endoscopy etc.), it is filled using the single intubation in aorta system
The easy structure for infusing multiple organ, the big animal origin organism organ 1 obtained using pig farm, in vitro Perfusion preservation.It utilizes
Blood or cell-free type circumfusion liquid supplement energy substrate and oxygen carrying, maintain organ vitality, and do not destroy abdominal cavity or chest
The anatomical structure of chamber organ helps doctor to grasp routine operation or minimal invasive techniques basic operation.To the full extent close to big dynamic
It while the effect of object experiment, is substantially reduced with cost, avoids ethics problem, and there are anatomical variations, keep complete
Normal anatomical structures, organ maintain vigour, the clear superiorities such as bleeding after operation damage.
As shown in Figure 10 to Figure 17, overall system architecture of the invention can be divided into top half, lower half portion, lifting column
43 three parts, top half are core component, and lower half portion is mainly pedestal and main accessories.Top half mainly includes machine
Box enclosure 40 and upper cover 55, and positioned at their internal core components: organism organ 1, organ storehouse 2, water bath 10, pump 7,
Oxygenator 5, filter bolt device 6, circulation line 8, return line 60, vascular catheterization interconnecting piece 64 and vascular catheterization 9 etc..In addition, upper half
Display bracket 36, abdominal distention 37, mis instruments or the scope entrance that part is additionally provided with display 35, supports display 35
38, tablet computer host 39, water bath temperature controller 42, instrument extension box 45 etc..Water can be accommodated by being equipped with inside casing 40
The heater storehouse 52 of bath cabinet 10.
Wherein, display 35 is used for display operation image or other operation informations, the display content of display 35 from
The hand that the operation image or tablet computer host 39 of laparoscope or the transmission of digestive endoscopy host in minimally invasive equipment compartment 48 transmit
Art Teaching video recording.Abdominal distention 37 is arranged in upper cover 55, and abdominal distention 37 includes but is not limited to circle, ellipse etc., abdomen
Bulge 37 is for simulating human abdomen or celioscope pneumoperitoneum state.Mis instruments or scope entrance 38 are arranged in abdominal distention 37
On, for accommodating laparoscopic instrument or scope hose.Intraoral illumination lamp 56 is provided in abdominal distention 37, illumination when for operating.
Organ storehouse 2 and water bath 10 are fastened for fastening organ storehouse 2, prevent the water-bath of 2 lower section of organ storehouse by organ storehouse fixed knob 59
Warm water buoyancy in case 10 causes organ storehouse 2 to float.40 front lower place of casing is provided with handle 44, is used for hanging apparatus extension box
45, instrument extension box 45 are for accommodating exercising device for spare.
Mis instruments Universal arm fixing seat 53 is provided with around upper cover 55, (including camera shooting bar is solid for fixing gimbals
Determine hole 18, image bar fixed handle 19 and universal structure lock handle 20, as shown in figure 21), it is minimally invasive for adjusting and fastening
The camera shooting bar of device is convenient for one man operation, substitutes assistant；In the front end of upper cover 55, towards abdominal distention 37 at be provided with it is miniature
Exhaust fan 41, miniature exhaust fan 41 are used to exclude the water vapour and operation medium-high frequency of organ storehouse 2 and the evaporation generation of water bath 10
Electric knife burns the smog of the generation of organism organ 1.In addition, have can be with rotating folding upper cover hinge 62 for upper cover 55.
Tablet computer host 39 has basic information database, records operator's essential information；There are operation points-scoring system, energy
It enough collects following parameter to be assessed: the indexs such as amount of bleeding, operating time, degree of trembling, degree-of-difficulty factor.Tablet computer host 39 has
There are video recording and storage system, to record operation video, and can play back.Tablet computer host 39 has network connecting function, uses
With realization device networking.Tablet computer host 39 can also connect electronic control system, with control panel and display screen 83
Function, as described in second part.
Lower half portion is mainly core with pedestal 61, and the symmetrical several castors 49 in periphery, 61 top of pedestal is provided with
There is oxygen cylinder 46 at minimally invasive equipment compartment 48 and electric knife storehouse 47,61 rear portion of pedestal.Wherein, minimally invasive equipment compartment 48 for accommodate laparoscope or
Digestive endoscopy host, electric knife storehouse 47 is for accommodating electric knife.Oxygen cylinder 46 is used for oxygen supply, is placed on oxygen bottle supporter 57
On, the exit of oxygen cylinder 46 is provided with oxygen flow adjusting table 51, for adjusting the gas output of oxygen cylinder 46.Lifting column 43 can
Height is adjusted, machine operating surface height is can adjust and adapts to different operation person height.
As shown in Figure 15-Figure 17, upper cover 55 has can be with rotating folding upper cover hinge 62, convenient for opening upper cover 55, quickly more
The consumptive materials such as parallel operation official storehouse 2, oxygenator 5, filter bolt device 6；There is intraoral illumination lamp 56 inside abdominal distention 37.Organ storehouse fixed knob 59 is used
In fastening organ storehouse 2, organ storehouse 2 and water bath 10 are fastened, prevent buoyancy from organ storehouse 2 being caused to float, and keeps contact enough
Area improves heat conduction efficiency.Pump 7 is fixed on inside casing 40, and oxygenator 5 and filter bolt device 6 are centrally located in same outer
In shell 54, it is fixed on inside casing 40.
As shown in figure 18, in upper cover 55 have mis instruments or scope entrance 38, mainly for laparoscope instruction camera shooting bar,
Needle holder being applied to surgery Minimally instrument approach, gives training training.Wherein mis instruments or 38 specific structure of scope entrance include: screw-cap
38-1, silica gel sealing piece 38-2 and spiral pedestal 38-3.Silica gel sealing piece 38-2 is anchored on spiral pedestal 38- by screw-cap 38-1
3, not only salable upper cover, but also for simulating mis instruments puncture.
As shown in figure 19, there is alimentary canal to operate approach 12, including esophagus entrance 11, rectum entrance 13 is main in upper cover 55
If simulating the structure of human body esophagus, anus, enter for digestive endoscopy soft lens, carries out digestive endoscopy training training.Preferably wrap
Esophagus entrance 11 is included, is entered for devices such as the superior gastrointestinal endoscopes such as gastroscope；Rectum entrance 13 is preferably included, for the row of collection
Let out the entrance of the digestive endoscopes device such as waste or Sigmoidoscope.
As shown in figure 20, instrument extension box 45 include: instrument jack 45-1, hook 45-2 and instrument box main body 45-3.Wherein,
Instrument box main body 45-3 is hollow structure, and side has instrument jack 45-1 and hook 45-2, links up with 45-2 perpendicular to instruments box
Main body is stretched out.By linking up with 45-2, instrument extension box 45 can be hung on the handle 44 in the front of teaching, training device.
As shown in figure 21, camera shooting bar gimbals include camera shooting bar fixation hole 18, image bar fixed handle 19 and universal
Structure latches handle 20.Wherein, camera shooting bar fixation hole 18 is used to accommodate the camera shooting bar of minimally invasive device, and camera shooting bar fixed handle 19 is used
Bar is imaged in locking, universal structure lock handle 20 is convenient for one man operation, substitutes assistant for adjusting universal structure and locking；
As shown in figure 22, also there is system of the invention bile to collect metering device 16, and urine collecting metering device 17 is used
To collect bile, urine, dynamic observation organ vigor.Bile collects metering device 16 and the setting of urine collecting metering device 17 exists
40 side of casing.
System of the invention further includes electronic control system, the power supply of electronic control system rely on power pack 21 (see
Low-voltage dc power supply 82 in Figure 23).Power pack 21 is located at 40 rear portion of casing.
As shown in figure 24, the core of the electronic control system of system of the invention is controller 67, the electronic control system
System includes controller 67 and control panel and display screen 83.Figure 24 shows the circuit diagram of the electronic control system.Wherein,
After incoming 67 analysis of controller of signal of temperature sensor 68, flow sensor 66, pressure sensor 69 is handled, pass through controller
The temperature of 67 control temperature maintenance devices 4, the revolving speed of control pump 7 control priming line to prevent injection pressure or Traffic Anomaly
70 folding condition of valve is clamped down on, timely alarm is carried out by alarm device 84 when device is abnormal situation.
Controller 67 is located near power pack 21, and controller 67 is collected temperature sensor 68, flow sensor 66, pressure and passed
The signal of sensor 69, after handling by analysis, can carry out control as follows: 1) revolving speed of control pump 7 prevents injection pressure or flow
It is abnormal, it avoids or Traffic Anomaly, even results in damage organism organ 1；2) control oxygenator heat cycles pump 71 and temperature dimension
Device 4 is held to maintain the temperature of organism organ 1 and circulation line 8；3) height for controlling lifting column 43 adapts to different height behaviour
Author；4) 56 brightness of intraoral illumination lamp is controlled, provides optimal brightness for training operation；5) control priming line is clamped down on valve 70 and is adjusted in time
Whole 8 folding condition of priming line；6) timely alarm is carried out by alarm device 84 when device is abnormal situation.Control panel
And display screen 83 is used for the state of display controller 67, and can manually adjust relevant parameter.
Embodiment described above, the only present invention more preferably specific embodiment, those skilled in the art is at this
The usual variations and alternatives carried out within the scope of inventive technique scheme should be all included within the scope of the present invention.
Claims (15)
1. a kind of organ perfusion's teaching and training system characterized by comprising
Organ storehouse (2): for accommodating organism organ (1) and collateral blood vessels；
Containing liquid chamber (3): it is located at below the organ storehouse (2), for storing circumfusion liquid；
Temperature maintenance device (4): for maintaining the temperature of organism organ (1)；
Priming line (8): the collateral blood vessels of connection containing liquid chamber (3) and organism organ (1), under the driving of pump (7), to described
Organism organ (1) and collateral blood vessels are pressurizeed, circumfusion；
Pump (7): it pressurizes to circulation line (8), is pressurizeed to the organism organ (1) and collateral blood vessels, recycles filling
Note；
Display (35) is used for display operation image；
Pedestal (61), is used to support, moves and goes up and down single unit system；
Organ perfusion's save set can the aorta system to organism pressurize, circumfusion, can fill simultaneously
Infuse single or multiple organism organs (1).
2. system according to claim 1, which is characterized in that
Multiple abdomen organs can be perfused simultaneously by abdominal aorta system in organ perfusion's save set, and wherein liver door is quiet
Arteries and veins (76) is irrigated without intubation by the circumfusion liquid that portalsystem flows back.
3. system according to claim 1, which is characterized in that organ perfusion's save set can pass through aorta pectoralis
Multiple thoracic organs are perfused simultaneously in system, and wherein pulmonary artery is irrigated without intubation by the circumfusion liquid of the right heart.
4. system according to claim 1, which is characterized in that further include:
Oxygenator (5): it is closed for circumfusion liquid to be continued oxygen；
It filters bolt device (6): being used for filtration cycle perfusion liquid.
5. system according to claim 1, which is characterized in that further include:
Upper cover (55): for closing organ storehouse (2) and temperature maintenance device (4)；
Lifting column (43), the lifting column (43) can adjust the height of operating platform, wherein the operating platform support housing
(40) and upper cover (55)；
Display bracket (36) is used to support display (35).
6. system according to claim 5, which is characterized in that further include:
Abdominal distention (37), abdominal distention (37) are arranged on upper cover (55), and for simulating human abdomen's protuberance, the abdomen is swollen
There is mis instruments or scope entrance (38), alimentary canal operation approach (12), mis instruments or scope entrance (38) on grand (37)
Enter for needle holder being applied to surgery Minimally instrument, alimentary canal operates approach (12) and enters for digestive endoscopy soft lens.
7. system according to claim 6, which is characterized in that
Alimentary canal operation approach (12) includes esophagus entrance (11) and rectum entrance (13), and esophagus entrance (11) is for above disappearing
Change road endoscope and image processing device to enter, rectum entrance (13) is for collecting discharged waste or entering for digestive endoscope device.
8. system according to claim 6, which is characterized in that
Intraoral illumination lamp (56) are provided in the abdominal distention (37), are arranged on upper cover (55) against the abdominal distention (37)
There are miniature exhaust fan (41).
9. system according to claim 5, which is characterized in that
It is provided with mis instruments Universal arm fixing seat (53) around upper cover (55), for fixing gimbals.
10. system according to claim 9, which is characterized in that the gimbals include:
Image bar fixation hole (18), camera shooting bar fixed handle (19) and universal structure lock handle (20).
11. system according to claim 1, which is characterized in that further include:
Temperature sensor (68), for monitoring the temperature of the circumfusion liquid in containing liquid chamber (3), organism organ 1；
Flow sensor (66), for monitoring the flow of the interior circumfusion liquid of priming line (8)；
Pressure sensor (69), for monitoring the pressure of the circumfusion liquid in priming line (8).
12. system according to claim 1, which is characterized in that further include:
Tablet computer host (39), tablet computer host (39) include basic information database, record operator's essential information；
With operation points-scoring system, following parameter can be collected and carry out quantitative evaluation: amount of bleeding, operating time, degree of trembling and difficulty system
Number index；Video recording and storage system, to record operation video, and can play back；Network connecting function, to realization device network
Connection and monitoring；Information can be shown on control panel and display screen (83).
13. system according to claim 11, which is characterized in that further include:
Controller (67), the controller (67) are configured as collecting temperature sensor (68), flow sensor (66), pressure biography
The signal of sensor (69) after handling by analysis, can carry out control as follows:
The revolving speed of control pump (7) prevents injection pressure or Traffic Anomaly, avoids or Traffic Anomaly, even results in damage organism device
Official (1)；
Control oxygenator heat cycles pump (71) and temperature maintenance device (4) to maintain organism organ (1) and circulation line (8)
Temperature, wherein oxygenator heat cycles pump (71) is used to extract out in the interior warm water of water bath (10), to follow to oxygenator (5)
Ring heating；
The height for controlling lifting column (43) adapts to different height operators；Intraoral illumination lamp (56) brightness is controlled, is mentioned for training operation
For optimal brightness；
Control priming line clamps down on the folding condition that valve (70) adjusts priming line (8) in time；When device is abnormal situation
Timely alarm is carried out by alarm device (84)；
The state of control panel and display screen (83) display controller (67), and relevant parameter can be manually adjusted.
14. system according to claim 2, which is characterized in that
There are diaphram suspended structure (14) inside the organ storehouse (2), for hanging diaphram (22), the normal of organ is closed on simulation
Anatomical position.
15. system according to claim 1, which is characterized in that
Minimally invasive equipment compartment (48), oxygen cylinder (46), bile is provided on the pedestal (61) to collect metering device (16) and/or urinate
Liquid collects metering device (17).
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| CN110859178A (en) * | 2019-12-23 | 2020-03-06 | 张嘉 | MRI (magnetic resonance imaging) -compatible in-vitro kidney perfusion system |
| WO2020192511A1 (en) * | 2019-03-22 | 2020-10-01 | 天一阁医疗科技(广州)有限公司 | Organ perfusion teaching and training system |
| CN113487953A (en) * | 2021-07-30 | 2021-10-08 | 北京博医时代教育科技有限公司 | Esophageal and gastric varices operation training model and manufacturing method thereof |
| CN113994954A (en) * | 2021-12-10 | 2022-02-01 | 广东省虚拟医学科技有限公司 | Organ in-vitro perfusion device |
| CN114373347A (en) * | 2020-12-15 | 2022-04-19 | 西安赛德欧医疗研究院有限公司 | Intelligent high-simulation training system for whole-organ surgery |
| CN115394163A (en) * | 2022-08-23 | 2022-11-25 | 南方医科大学 | Isolated organ perfusion simulation device and method |
| WO2023061121A1 (en) * | 2021-10-12 | 2023-04-20 | 北京博医时代医疗科技有限公司 | Surgical simulation device and surgical training system |
| WO2023061120A1 (en) * | 2021-10-12 | 2023-04-20 | 北京博医时代医疗科技有限公司 | Perfusion platform for training |
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| CN112772632A (en) * | 2020-12-31 | 2021-05-11 | 重庆北部宽仁医院 | Isolated liver perfusion device |
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