CN110449196A - A kind of multidirectional isocon - Google Patents

A kind of multidirectional isocon Download PDF

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Publication number
CN110449196A
CN110449196A CN201910885089.7A CN201910885089A CN110449196A CN 110449196 A CN110449196 A CN 110449196A CN 201910885089 A CN201910885089 A CN 201910885089A CN 110449196 A CN110449196 A CN 110449196A
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CN
China
Prior art keywords
isocon
multidirectional
outlet
single order
entrance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910885089.7A
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Chinese (zh)
Inventor
王升启
肖瑞
荣振
王封
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Pharmacology and Toxicology of AMMS
Academy of Military Medical Sciences AMMS of PLA
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Institute of Pharmacology and Toxicology of AMMS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Institute of Pharmacology and Toxicology of AMMS filed Critical Institute of Pharmacology and Toxicology of AMMS
Priority to CN201910885089.7A priority Critical patent/CN110449196A/en
Publication of CN110449196A publication Critical patent/CN110449196A/en
Pending legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The present invention provides a kind of multidirectional isocons, are related to biochemical test equipment technology field.The multidirectional isocon includes pipeline ontology, and pipeline ontology is provided with an entrance and multiple outlets, and circulation distance of the entrance apart from any outlet is equal, the M power that the quantity of outlet is 2, wherein M is the natural number greater than 0.Multidirectional isocon of the invention has been arranged in correspondence with multiple outlets with entrance, improves the operating efficiency of experiment so that multiple outlets are impartial to distribute medium to be conveyed by the special setting to conveying distance and number of channels.

Description

A kind of multidirectional isocon
Technical field
The present invention relates to biochemical test equipment technology fields, in particular to a kind of multidirectional isocon.
Background technique
In the medical researches such as nucleic acid extraction, nucleic acid amplification experiment, need one or more kinds of nucleic acid solution samples etc. Amount injects multiple reaction sockets.Currently, generally injecting nucleic acid solution sample, the fluid injection to reaction socket by liquid injection pipe in experiment Pipe can front and rear, left and right it is mobile, and being capable of oscilaltion.However, can not also contract even if the operation of liquid injection pipe is convenient again, rapid again Short whole sample injection length, while when liquid injection pipe moves between adjacent reaction socket, nucleic acid solution sample inevitably drips It falls on experimental work platform, causes the pollution of equipment and working environment.
Summary of the invention
The purpose of the present invention is to provide a kind of multidirectional isocons, can be by nucleic acid solution sample equivalent to be tested point Stream realizes the purpose disposably injected to multiple reaction sockets.
The embodiment of the present invention is achieved in that
A kind of multidirectional isocon comprising pipeline ontology, the pipeline ontology are provided with an entrance and multiple outlets, institute It states circulation distance of the entrance apart from any outlet to be equal, the M power that the quantity of the outlet is 2, wherein M is greater than 0 Natural number.
Pipeline ontology as introduce nucleic acid solution sample and to it is multiple reaction sockets convey tools, entrance respectively with it is more A outlet, since the distance of solution from any one outlet of entrance flow direction is equal, and entrance is logical in pipeline ontology To any one export lumen bore be consistent, so, from entrance inject sample of nucleic acid solution after pipeline ontology, Flow, flow velocity from each outlet outflow are equivalent.Also, the M power that the quantitative design of outlet is 2, M are greater than 0 Natural number, i.e. export volume be 2,4,8,16 ... at this point, every two outlet can be divided by a delivery pipe Two plume roads realize that the impartial of solution sample shunts.
In preferred embodiments of the present invention, the pipeline ontology includes inflow pipe and multiple single order isocons;Multiple institutes Upstream port after stating single order isocon parallel connection is connected to the downstream port of the inflow pipe;The upstream port of the inflow pipe is The entrance, the downstream port of any single order isocon are the outlet.It has the technical effect that inflow pipe will be wait test Nucleic acid solution sample import multiple single order isocons in parallel, realize that equivalent shunts.And each single order isocon at this time Downstream port is outlet, i.e., the quantity of single order isocon is also 2 M power, and wherein M is the natural number greater than 0.Also, at this time Single order isocon runner length answer it is equal.When the quantity of single order isocon is 2, exporting is two, in left and right two Side separated structure arrangement.When the quantity of single order isocon is 4, outlet can be distributed in a manner of a line, can also be in Two rows, two column formal distribution.It should be noted that the quantity of single order isocon is at most only 4, (quantity exported at this time is also most Mostly 4), when more than 4, it not can guarantee the distance between each outlet and entrance and be equal.And if necessary More multiple exit is set, then only setting inflow pipe and single order isocon are not enough, needs to set again in the downstream of single order isocon Set other isocons.
In preferred embodiments of the present invention, the pipeline ontology includes inflow pipe, two single order isocons and multiple two Rank isocon;Upstream port after two single order isocons are in parallel is connected to the downstream port of the inflow pipe, Ren Yisuo The downstream port for stating single order isocon is connected to the upstream port after several second order isocons parallel connections;The inflow pipe it is upper Trip port is the entrance, and the downstream port of any second order isocon is the outlet;The quantity of the second order isocon For 2 n times power, wherein N is the natural number greater than 1.It has the technical effect that will be to be tested by two single order isocons Nucleic acid solution sample equivalent is transported to the second order isocon in downstream, then, such as the case where ibid one embodiment describes, each 4 outlets can be at most arranged in the downstream of second order isocon, i.e., at this time export volume up to 8.
In preferred embodiments of the present invention, multiple outlets are arranged in uniline.It has the technical effect that when experiment is set When standby middle reaction tube placing groove is a column distribution, then should by multiple exit design Cheng Yilie of multidirectional isocon, also, adjacent two The spacing of a outlet is equal with the spacing of two neighboring reaction tube placing groove.
In preferred embodiments of the present invention, multiple outlets are in annulus in the arrangement of two rows or multiple outlets Shape distribution.It has the technical effect that when in experimental facilities reaction tube placing groove be two row multiple rows distribution when, then should be by multidirectional shunting Multiple exit designs of pipe are at two row multiple rows, also, between the spacing of two neighboring outlet and two neighboring reaction tube placing groove Away from equal.
In preferred embodiments of the present invention, the angle between the inflow pipe and the single order isocon is obtuse angle.Its The multidirectional isocon for having the technical effect that the design structure, when inflow pipe, which is erect, to be placed, the upstream port of single order isocon is high In downstream port, i.e. single order isocon is tilted down structure, quickly flows out conducive to nucleic acid solution sample.
It further include inlet duct in preferred embodiments of the present invention;The inlet duct is provided with multiple fluid injection imports With one go out liquid interface, multiple fluid injection imports with it is described go out liquid interface be connected to, it is described go out liquid interface for it is described enter Mouth connection.It has the technical effect that the setting of inlet duct is used for while importing multiple nucleic acids solution sample.When needs use When multiple nucleic acids solution sample, reaction socket can be introduced simultaneously.
In preferred embodiments of the present invention, the inlet duct is Y-shaped structure.It has the technical effect that Y-shaped knot The inlet duct of structure includes that two fluid injection imports and one go out liquid interface.
Further include plug in preferred embodiments of the present invention, the plug for block the entrance and/or it is described go out Mouthful.It has the technical effect that plug can be blocked temporarily or be blocked before use, prevents from getting dirty inside multidirectional isocon Dye.Wherein, plug can also be replaced with buckle closure.
In preferred embodiments of the present invention, the pipeline ontology is made of plastics.It has the technical effect that multidirectional shunting Pipe itself is medical disposable material, and plastic material is light, at low cost and molding rapid and convenient.It can disposal molding as required For uniline formula or multirow formula isocon, nucleic acid conventional efficient is improved.
The beneficial effect of the embodiment of the present invention is:
Multidirectional isocon of the invention has been arranged in correspondence with multiple outlets with entrance, by conveying distance and port number The special setting of amount improves the operating efficiency of experiment so that multiple outlets are impartial to distribute medium to be conveyed.
Detailed description of the invention
In order to illustrate the technical solution of the embodiments of the present invention more clearly, below will be to needed in the embodiment attached Figure is briefly described, it should be understood that the following drawings illustrates only certain embodiments of the present invention, therefore is not construed as pair The restriction of range for those of ordinary skill in the art without creative efforts, can also be according to this A little attached drawings obtain other relevant attached drawings.
Fig. 1 is the main view for the multidirectional isocon that the embodiment of the present invention one provides;
Fig. 2 is the top view for the multidirectional isocon that the embodiment of the present invention one provides;
Fig. 3 is the sectional view along A-A in Fig. 2;
Fig. 4 is the main view of multidirectional isocon provided by Embodiment 2 of the present invention;
Fig. 5 is the top view of multidirectional isocon provided by Embodiment 2 of the present invention;
Fig. 6 is the B-B direction cross-sectional view in Fig. 5;
Fig. 7 is the main view for the multidirectional isocon that the embodiment of the present invention three provides;
Fig. 8 is the top view for the multidirectional isocon that the embodiment of the present invention three provides;
Fig. 9 is C-C in Fig. 8 to cross-sectional view;
Figure 10 is the main view for the multidirectional isocon that the embodiment of the present invention four provides;
Figure 11 is the top view for the multidirectional isocon that the embodiment of the present invention four provides;
Figure 12 is D-D in Figure 11 to cross-sectional view;
Figure 13 is the cross-sectional view of the 5th kind of multidirectional isocon provided in an embodiment of the present invention;
Figure 14 is the cross-sectional view of the 6th kind of multidirectional isocon provided in an embodiment of the present invention;
Figure 15 is the cross-sectional view of the 7th kind of multidirectional isocon provided in an embodiment of the present invention.
In figure: 100- pipeline ontology;101- entrance;The outlet 102-;103- inflow pipe;104- single order isocon;105- bis- Rank isocon;200- inlet duct;201- fluid injection import;202- goes out liquid interface;300- plug.
Specific embodiment
In order to make the object, technical scheme and advantages of the embodiment of the invention clearer, below in conjunction with the embodiment of the present invention In attached drawing, technical scheme in the embodiment of the invention is clearly and completely described, it is clear that described embodiment is A part of the embodiment of the present invention, instead of all the embodiments.The present invention being usually described and illustrated herein in the accompanying drawings is implemented The component of example can be arranged and be designed with a variety of different configurations.
Therefore, the detailed description of the embodiment of the present invention provided in the accompanying drawings is not intended to limit below claimed The scope of the present invention, but be merely representative of selected embodiment of the invention.Based on the embodiments of the present invention, this field is common Technical staff's every other embodiment obtained without creative efforts belongs to the model that the present invention protects It encloses.
It should also be noted that similar label and letter indicate similar terms in following attached drawing, therefore, once a certain Xiang Yi It is defined in a attached drawing, does not then need that it is further defined and explained in subsequent attached drawing.
In the description of the present invention, it should be noted that term " center ", "upper", "lower", "left", "right", "vertical", The orientation or positional relationship of the instructions such as "horizontal", "inner", "outside" is to be based on the orientation or positional relationship shown in the drawings, or be somebody's turn to do Invention product using when the orientation or positional relationship usually put, be merely for convenience of description of the present invention and simplification of the description, without It is that the device of indication or suggestion meaning or element must have a particular orientation, be constructed and operated in a specific orientation, therefore not It can be interpreted as limitation of the present invention.In addition, term " first ", " second ", " third " etc. are only used for distinguishing description, and cannot manage Solution is indication or suggestion relative importance.
In addition, the terms such as term "horizontal", "vertical", " pendency " are not offered as requiring component abswolute level or pendency, and It is that can be slightly tilted.It is not to indicate the structure if "horizontal" only refers to that its direction is more horizontal with respect to for "vertical" It has to fully horizontally, but can be slightly tilted.
In the description of the present invention, it is also necessary to which explanation is unless specifically defined or limited otherwise, term " setting ", " installation ", " connected ", " connection " shall be understood in a broad sense, for example, it may be fixedly connected, may be a detachable connection or one Connect to body;It can be mechanical connection, be also possible to be electrically connected;It can be directly connected, it can also be indirect by intermediary It is connected, can be the connection inside two elements.For the ordinary skill in the art, on being understood with concrete condition State the concrete meaning of term in the present invention.
With reference to the accompanying drawing, it elaborates to some embodiments of the present invention.In the absence of conflict, following Feature in embodiment and embodiment can be combined with each other.
First embodiment:
Fig. 1 is the main view for the multidirectional isocon that the embodiment of the present invention one provides;Fig. 2 is what the embodiment of the present invention one provided The top view of multidirectional isocon;Fig. 3 is the sectional view along A-A in Fig. 2.Fig. 1, Fig. 2, Fig. 3 are please referred to, the present embodiment provides one kind Multidirectional isocon comprising pipeline ontology 100, pipeline ontology 100 are provided with an entrance 101 and multiple outlets 102, entrance The 101 circulation distance apart from any outlet 102 is equal, the M power that the quantity for exporting 102 is 2, wherein M is oneself greater than 0 So number.
Further, as shown in Figure 1, Figure 2, Figure 3 shows, pipeline ontology 100 includes inflow pipe 103 and two single order isocons 104;Upstream port after two 104 parallel connections of single order isocon is connected to the downstream port of inflow pipe 103;Inflow pipe 103 it is upper Trip port is entrance 101, and the downstream port of any single order isocon 104 is outlet 102.At this point, M is 1,102 quantity is exported It is two.
At this point, single order isocon 104 can averagely shunt the solution sample from inflow pipe 103, two single order isocons 104 downstream port is outlet 102, spacing between two outlets 102 should with two neighboring reaction tube placing groove away from From equal.
In the above-described embodiments, pipeline ontology 100 is conveyed as introducing nucleic acid solution sample and to multiple reaction sockets Tool, entrance 101 are connected to multiple outlets 102 respectively.Due to solution from entrance 101 flow direction any one outlet 102 away from From being equal, and the lumen bore that entrance 101 leads to any one outlet 102 in pipeline ontology 100 is consistent, institute With the sample of nucleic acid solution injected from entrance 101 is after pipeline ontology 100, from flow, the stream of each 102 outflow of outlet Speed is equivalent.Also, the quantitative design of outlet 102 is 2, at this point, every two outlet 102 can be by a delivery pipe point At two plume roads, realize that the impartial of solution sample shunts.
Second embodiment:
Fig. 4 is the main view of multidirectional isocon provided by Embodiment 2 of the present invention;Fig. 5 is provided by Embodiment 2 of the present invention The top view of multidirectional isocon;Fig. 6 is the B-B direction cross-sectional view in Fig. 5.Referring to figure 4., Fig. 5, Fig. 6, the present embodiment provides one kind Multidirectional isocon, roughly the same with the multidirectional isocon of first embodiment, the difference of the two is in the multidirectional of the present embodiment In isocon, the quantity of single order isocon 104 is four.Upstream port and inflow pipe after four 104 parallel connections of single order isocon 103 downstream port connection;The upstream port of inflow pipe 103 is entrance 101, and the downstream port of any single order isocon 104 is Outlet 102.
Further, as shown in Fig. 4, Fig. 5, Fig. 6, four single order isocons 104 are in the column arrangement of two rows two.At this point, outlet 102 quantity is four.
It should be noted that the quantity of single order isocon 104 is at most only 4, (quantity of outlet 102 is also up at this time 4), when more than 4, it not can guarantee the distance between each outlet 102 and entrance 101 and be equal.And if needed More multiple exit 102 is set, then only setting inflow pipe 103 and single order isocon 104 are not enough, is needed in single order isocon Other isocons are arranged in 104 downstream again.
If setting 6,8 for single order isocon 104, although flow can also equivalent divide equally, outlet 102 position It sets and is difficult to corresponding with the position of actual reaction tube placing groove, therefore the quantity of general single order isocon 104 is 4, outlet 102 Only 4.
3rd embodiment:
Fig. 7 is the main view for the multidirectional isocon that the embodiment of the present invention three provides;Fig. 8 is what the embodiment of the present invention three provided The top view of multidirectional isocon;Fig. 9 is C-C in Fig. 8 to cross-sectional view.Fig. 7, Fig. 8, Fig. 9 are please referred to, the present embodiment provides one kind Multidirectional isocon, roughly the same with first embodiment, the multidirectional isocon of second embodiment, the difference of the two is in this reality It applies in the multidirectional isocon of example, pipeline ontology 100 includes 103, two single order isocons 104 of inflow pipe and four second order isocons 105;Upstream port after two 104 parallel connections of single order isocon is connected to the downstream port of inflow pipe 103, any single order isocon 104 downstream port is connected to the upstream port after two 105 parallel connections of second order isocon;The upstream port of inflow pipe 103 be into Mouth 101, the downstream port of any second order isocon 105 are outlet 102.At this point, the quantity of second order isocon 105 is 4.
Further, as shown in Fig. 7, Fig. 8, Fig. 9, four single order isocons 104 are arranged in a line.
It should be noted that nucleic acid solution sample equivalent to be tested is transported to down by two single order isocons 104 The second order isocon 105 of trip, then, such as the case where ibid one embodiment describes, the downstream of each second order isocon 105 4 outlets 102 can be at most set, i.e., export 102 quantity at this time up to 8.
Fourth embodiment:
Figure 10 is the main view for the multidirectional isocon that the embodiment of the present invention four provides;Figure 11 is that the embodiment of the present invention four provides Multidirectional isocon top view;Figure 12 is D-D in Figure 11 to cross-sectional view.Please refer to Figure 10, Figure 11, Figure 12, the present embodiment A kind of multidirectional isocon is provided, roughly the same with the multidirectional isocon of 3rd embodiment, the difference of the two is in this implementation In the multidirectional isocon of example, the lower exit 102 of four second order isocons 105 is separately connected two three ranks in parallel again and shunts Pipe.Its mode of communicating and 3rd embodiment are similar.At this point, 102 quantity of outlet are 8, also, 8 outlets 102 are arranged in two rows two Distribution.
Figure 13 is the cross-sectional view of the 5th kind of multidirectional isocon provided in an embodiment of the present invention.Further, any of the above-described On the basis of embodiment, as shown in figure 13, the angle between inflow pipe 103 and single order isocon 104 is obtuse angle.
Figure 14 is the cross-sectional view of the 6th kind of multidirectional isocon provided in an embodiment of the present invention.In the base of any of the above-described embodiment It further include inlet duct 200 as shown in figure 14 on plinth;Inlet duct 200 is provided with multiple fluid injection imports 201 and one goes out liquid Interface 202, multiple fluid injection imports 201 are connected to liquid interface 202 out, and liquid interface 202 with entrance 101 for connecting out.Wherein, Inlet duct 200 is Y-shaped structure.
Figure 15 is the cross-sectional view of the 7th kind of multidirectional isocon provided in an embodiment of the present invention.In the base of any of the above-described embodiment It further include plug 300, plug 300 is for blocking entrance 101 and/or outlet 102 as shown in figure 15 on plinth.
Further, pipeline ontology 100 is made of plastics.
These are only the preferred embodiment of the present invention, is not intended to restrict the invention, for those skilled in the art For member, the invention may be variously modified and varied.All within the spirits and principles of the present invention, it is made it is any modification, Equivalent replacement, improvement etc., should all be included in the protection scope of the present invention.

Claims (10)

1. a kind of multidirectional isocon, which is characterized in that including pipeline ontology (100), the pipeline ontology (100) is provided with one Entrance (101) and multiple outlets (102), circulation distance of the entrance (101) apart from any outlet (102) are equal, The M power that the quantity of the outlet (102) is 2, wherein M is the natural number greater than 0.
2. multidirectional isocon according to claim 1, which is characterized in that the pipeline ontology (100) includes inflow pipe (103) and multiple single order isocons (104);Upstream port after multiple single order isocons (104) are in parallel becomes a mandarin with described Manage the downstream port connection of (103);The upstream port of the inflow pipe (103) is the entrance (101), any single order point The downstream port of flow tube (104) is the outlet (102).
3. multidirectional isocon according to claim 1, which is characterized in that the pipeline ontology (100) includes inflow pipe (103), two single order isocons (104) and multiple second order isocons (105);After two single order isocons (104) are in parallel Upstream port be connected to the downstream port of the inflow pipe (103), the downstream port of any single order isocon (104) with Upstream port connection after several second order isocons (105) are in parallel;The upstream port of the inflow pipe (103) enters described in being Mouth (101), the downstream port of any second order isocon (105) are the outlet (102);The second order isocon (105) Quantity be 2 n times power, wherein N is natural number greater than 1.
4. multidirectional isocon according to claim 2 or 3, which is characterized in that multiple outlets (102) are arranged in uniline Cloth.
5. multidirectional isocon according to claim 2 or 3, which is characterized in that multiple outlets (102) are arranged in two rows Cloth or multiple described outlet (102) distributions annular in shape.
6. multidirectional isocon according to claim 2 or 3, which is characterized in that the inflow pipe (103) and the single order point Angle between flow tube (104) is obtuse angle.
7. multidirectional isocon according to claim 2 or 3, which is characterized in that further include inlet duct (200);It is described enter Conductance pipe (200) is provided with multiple fluid injection imports (201) and one goes out liquid interface (202), and multiple fluid injection imports (201) are equal It is connected to liquid interface (202) out, described liquid interface (202) out with the entrance (101) for connecting.
8. multidirectional isocon according to claim 7, which is characterized in that the inlet duct (200) is Y-shaped structure.
9. multidirectional isocon according to claim 2 or 3, which is characterized in that further include plug (300), the plug (300) for blocking the entrance (101) and/or the outlet (102).
10. multidirectional isocon according to claim 2 or 3, which is characterized in that the pipeline ontology (100) is by plastics system At.
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CN105082428A (en) * 2015-07-22 2015-11-25 南京红宝丽新材料有限公司 Material distribution boom assembly used for polyurethane insulation board continuous production line
CN204944263U (en) * 2015-07-23 2016-01-06 中国石油化工股份有限公司 A kind of fluid distribution pipe and cooling device
CN204922334U (en) * 2015-08-21 2015-12-30 厦门百美特生物材料科技有限公司 Isobaric reposition of redundant personnel pipeline
CN205667543U (en) * 2016-04-05 2016-11-02 温州医科大学 New-type air-flow stimulating apparatus
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