CN1104475A - Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation - Google Patents

Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation Download PDF

Info

Publication number
CN1104475A
CN1104475A CN 93121181 CN93121181A CN1104475A CN 1104475 A CN1104475 A CN 1104475A CN 93121181 CN93121181 CN 93121181 CN 93121181 A CN93121181 A CN 93121181A CN 1104475 A CN1104475 A CN 1104475A
Authority
CN
China
Prior art keywords
blood oxygen
signal
fixed
pulse
pick
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 93121181
Other languages
Chinese (zh)
Inventor
杨玉星
彭涤芳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huazhong University of Science and Technology
Original Assignee
Huazhong University of Science and Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Huazhong University of Science and Technology filed Critical Huazhong University of Science and Technology
Priority to CN 93121181 priority Critical patent/CN1104475A/en
Publication of CN1104475A publication Critical patent/CN1104475A/en
Pending legal-status Critical Current

Links

Images

Landscapes

  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

This invention refers to a medical instrument which is suitable for measuring the degree of blood oxygen saturation in human artery. The instrument adopts double wavelength split-phase moudulation to realize the process of optical measurement. The instrument having the same functions and same measure accuracy compared with the general product, has low cost as it requires lower standard for elements and parts and raw materials, thus it's easy to spread in the country.

Description

Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation
The present invention relates to a kind of medical apparatus and instruments.
No wound, the continuous real-time human body artery blood oxygen saturation of measuring can be conveniently used in occasions such as severe disease danger people monitoring, first aid, anesthesia, are the modern important means of performing the operation, guarding process.For example " a kind of reflective hybrid optical pick off that is used for measuring whole blood content of hemoglobin and oxygen concentration " (A Miniature Hybrid Reflection TypeOptical Sensor for Measurement of Hemog lobin Content andO xygen Saturation of Whole Blood. IEEE TRAN. ON BIOMED.ENG.Vol35, NO.3,1987) this employing microelectronics integrated technology, utilize hybrid optical pick off and timesharing thereof to drive, method that sampling keeps and corresponding pulse oximeter thereof, its shortcoming is that measurement sensitivity is lower, when adopting COMPUTER CALCULATION, must adopt the A/D converter of high conversion accuracy, the cost height, domestic being difficult to promotes the use of.
At the shortcoming that above-mentioned prior art exists, task of the present invention provides a kind of pulse blood oxygen multi-wavelength optical measuring method and pulse blood oxygen monitor thereof of dual wavelength phase-splitting modulator approach.
Method of the present invention is measured the variation of two wavelength light through the blood light absorption for adopting two light beams of different wavelengths at the same place of the shallow table tremulous pulse of human body body, and with two signal ratios directly by testing the empirical equation SaO that is tried to achieve 2=A-B(I λ 2,/I λ 1) ask blood oxygen saturation, and be to implement this method, of the present invention is to utilize dual wavelength phase-splitting modulation method to realize above-mentioned optical measurement process, promptly with square-wave generator 20(Fig. 3) the generation frequency is that 1KHz, dutycycle are 1: 2 square wave, one the road to pulsed constant-flow driver 22, another road enters pulsed constant- flow driver 23,22 and 23 through phase inverter 21 and is used for driving sensor mixing led light source 2.Photelectric receiver 3 on the pick off 11 and pre-arcing road 7 are transferred to measuring circuit input 1N(24 with mixed signal), and send into separately after distinguishing through two electrical switches of working asynchronously with driver and amplify two high-frequency modulation signal HO that obtain in the amplifier 27 and 28 1T HO 2Be respectively applied for the identification sensor positional fault, and the low frequency useful signal that carries on respectively with modulation signal through accurate demodulator amplifier 29 and 30 again, promptly the volume pulsation signal of different wave length is separated to be in harmonious proportion and is amplified, and restores the actual signal O that fights 1And O 2
According to the human body artery ohmeda 3700 pulse oxmeter system principle diagram of said method development as shown in Figure 2, it is by device pick off 11, measurement amplifying circuit 12 and single-chip microcomputer 8098CPU(15) constitute, described pick off 11 as shown in Figure 1, it is fixed by shell 1 usefulness the axle 9 that two halfbodies up and down constitute, and two halfbodies all can rotate around it up and down.Be closely attached on axle 9 spring 6 one ends and be fixed in upper semi-body, the other end is fixed in lower semi-body, and to realize opening and closing up motion of two halfbodies, shell 1 is hollow or solid, the rounded or polygon of the outer casing inner wall after closing up, interior laminating sponge 10.The LED pipe 2 that contains 2 tube cores is fixed on the halfbody, and optical-electrical converter 3 is fixed on another halfbody, and their center is relative, on LED pipe 2 and optical-electrical converter 3 scattering sheet 4 is housed, and is fixing with ring-shaped rubber 5.Pre-arcing road 7 is fixed in the housing 1,8 connects with measuring circuit by going between.
Advantage of the present invention can reduce the requirement to pick off owing to adopt dual wavelength phase-splitting modulator approach, therefore can directly adopt homemade photoelectric device design pick off, to element and material require lowly, cost is low, is suitable for promoting the use of at home.
Description of drawings is as follows:
Accompanying drawing 1a pick off passes structure principle chart
Accompanying drawing 1b is the B-B cutaway view of Fig. 1 a
Accompanying drawing 2 human body artery ohmeda 3700 pulse oxmeter systems
Theory diagram
Accompanying drawing 3 dual wavelength phase-splitting modulation method measuring method theory diagrams.
Accompanying drawing 4 measuring circuit figure
In conjunction with the accompanying drawings invention is further specified as follows:
The monitor system principle as shown in Figure 2, pick off 11 through go between 8 with measure amplifying circuit 12 and link to each other, the modulated light source circuit 13 in 12 produces the pulse signal driving composite LED pipe 2 of frequency 1KHz.Optical signal is sent into the input 1N that measures amplifying circuit 14 through photelectric receiver 3, pre-arcing road 7, its output signal is two-way high-frequency signal HO 1And HO 2, two-way volume pulsation signal O 1And O 2Respectively through single-chip microcomputer 8098 CPU(15) include four road A/D converter synchronous acquisition storages.The EPROM(18 that comprises 16,8 function keys 17 of 64 * 240 lattice lcd display, 16K byte in the Single Chip Microcomputer (SCM) system) and the RAM(19 of 32K byte) etc. the basic element of character.Like this, can finish judgement according to blood oxygen measuring principle to the correctness of two signals, to two signal synchronous collections, storage, digital filtering, automatically discern pulse crest, calculate SaO automatically 2And pulse frequency, display waveform stores 24 hours detected value in real time, shows 24 hours trend variation diagrams, and functions such as warning certainly are dynamically connected.Dual wavelength phase-splitting modulator approach measuring circuit as shown in Figure 4, it is corresponding one by one with theory diagram shown in Figure 3, wherein C 1And C 2Be used to drive the composite LED pipe, 1N is the input of sensor signal.HO 1And HO 2Be high-frequency modulation signal output, be used for the discriminating sensor correct position and whether reach correcting measured results, O 1And O 2For useful low frequency signal is a volume pulsation wave, the input computer.

Claims (2)

1, a kind of pulse blood oxygen multi-wavelength optical measuring method adopts two light beams of different wavelengths, and the same place of spattering the table tremulous pulse at the human body body measures the variation of two wavelength light through the blood light absorption, and with two signal ratios directly by testing the empirical equation SaO tried to achieve 2=A-B (I λ 2/ I λ 1) ask blood oxygen saturation, it is characterized by and adopt dual wavelength phase-splitting modulation method to implement above-mentioned optical measurement process, promptly producing frequency with square-wave generator (20) is 1KH 2, dutycycle is 1: 2 square wave, one the road to pulsed constant-flow driver (22), another road enters pulsed constant-flow driver (23) through phase inverter (21), (22) and (23) be used for driving sensor mixing led light source (2), photelectric receiver (3) and pre-arcing road (7) on the pick off (11) are transferred to measuring circuit input 1N (24) with mixed signal, and through sending into amplifier (27) and (28) middle amplification separately, two high-frequency modulation signal HO that obtain after two electrical switches differentiations that work asynchronously with driver 1And HO 2Be respectively applied for the identification sensor positional fault, and the low frequency useful signal that carries on respectively with modulation signal through accurate demodulator amplifier (29) and (30) again, the volume pulsation signal of seal different wave length is separated to be in harmonious proportion and is amplified, and restores actual pulse signal O 1And O 2
2, human body artery ohmeda 3700 pulse oxmeter according to the described method of claim 1, it is by pick off (11), measure amplifying circuit (12), single-chip microcomputer 8098CPU(15) constitutes, it is fixing with axle (9) by the shell (1) that two halfbodies up and down constitute to it is characterized by described pick off, two halfbodies all can rotate around it up and down, spring (6) one ends that are closely attached on axle (9) are fixed in upper semi-body, the other end is fixed in lower semi-body, to realize opening and closing up motion of two halfbodies, shell 1 is hollow or solid, rounded or the polygon of outer casing inner wall after closing up, interior laminating sponge (10), the LED tube core (2) that includes the tribute of 2 pipes is fixed on the halfbody, optical-electrical converter (3) is fixed on another halfbody, their center is relative, on LED pipe (2) and optical-electrical converter (3) scattering sheet (4) is housed, and is fixing with rubber turn (5), pre-arcing road (7) is fixed in the housing (1), connects with measuring circuit by lead-in wire (8).
CN 93121181 1993-12-29 1993-12-29 Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation Pending CN1104475A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 93121181 CN1104475A (en) 1993-12-29 1993-12-29 Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 93121181 CN1104475A (en) 1993-12-29 1993-12-29 Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation

Publications (1)

Publication Number Publication Date
CN1104475A true CN1104475A (en) 1995-07-05

Family

ID=4993600

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 93121181 Pending CN1104475A (en) 1993-12-29 1993-12-29 Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation

Country Status (1)

Country Link
CN (1) CN1104475A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100384373C (en) * 2006-05-30 2008-04-30 合肥安恒光电有限公司 Calibrated tester of oximeter
CN100425197C (en) * 2002-01-31 2008-10-15 拉夫伯勒大学企业有限公司 Venous pulse oximetry
CN101080192B (en) * 2004-12-14 2010-09-08 皇家飞利浦电子股份有限公司 Integrated pulse oximetry sensor
CN101884525A (en) * 2010-06-18 2010-11-17 上海理工大学 Portable device for real-time dynamic medical monitoring system
US8050730B2 (en) 2005-12-23 2011-11-01 Shenzhen Mindray Bio-Medical Electrics Co., Ltd. Method and apparatus for eliminating interference in pulse oxygen measurement
CN102319075A (en) * 2011-08-17 2012-01-18 天津大学 Blood oxygen saturation measuring device and measuring method
US8280472B2 (en) 2007-07-19 2012-10-02 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Method and apparatus for measuring blood oxygen saturation
CN103349553A (en) * 2013-08-01 2013-10-16 赵巍 Double-wavelength differential near-infrared non-invasive glucose meter

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100425197C (en) * 2002-01-31 2008-10-15 拉夫伯勒大学企业有限公司 Venous pulse oximetry
CN101080192B (en) * 2004-12-14 2010-09-08 皇家飞利浦电子股份有限公司 Integrated pulse oximetry sensor
US8050730B2 (en) 2005-12-23 2011-11-01 Shenzhen Mindray Bio-Medical Electrics Co., Ltd. Method and apparatus for eliminating interference in pulse oxygen measurement
CN100384373C (en) * 2006-05-30 2008-04-30 合肥安恒光电有限公司 Calibrated tester of oximeter
US8280472B2 (en) 2007-07-19 2012-10-02 Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Method and apparatus for measuring blood oxygen saturation
CN101884525A (en) * 2010-06-18 2010-11-17 上海理工大学 Portable device for real-time dynamic medical monitoring system
CN102319075A (en) * 2011-08-17 2012-01-18 天津大学 Blood oxygen saturation measuring device and measuring method
CN103349553A (en) * 2013-08-01 2013-10-16 赵巍 Double-wavelength differential near-infrared non-invasive glucose meter

Similar Documents

Publication Publication Date Title
US5348004A (en) Electronic processor for pulse oximeter
CA2179023A1 (en) Medical sensor with amplitude independent output
US6113541A (en) Noninvasive blood chemistry measurement method and system
US5431159A (en) Pulse oximetry
US4948248A (en) Blood constituent measuring device and method
CA1266785C (en)
CA2238958A1 (en) Method and apparatus for facilitating compatibility between pulse oximeters and sensor probes
NZ226517A (en) Optical oximeter: readings at pulse peaks integrated
EP0361999A1 (en) Probe for optical sensor
CA2180128A1 (en) Non-invasive non-spectrophotometric infrared measurement of blood analyte concentrations
CN1104475A (en) Method for measuring blood oxygen content by multiple wave length optical method and monitor for degree of blood oxygen saturation
US6862542B2 (en) Erythema measuring device
EP0232234A3 (en) A device for determining depth of anaesthesia
Baldini et al. In vivo optical-fibre pH sensor for gastro-oesophageal measurements
CN103027691A (en) Digital measuring device and digital measuring method for physiological and biochemical parameters
KR20060122567A (en) Tele-monitoring system for living body
CN104013385A (en) Skin sebum transferring probe and skin sebum secretion measuring method and device
US20220330894A1 (en) Contactless intelligent monitor and its detection method
CN112741600B (en) Frequency domain near-infrared light detection device for measuring optical parameters of biological tissues
CN113229789A (en) Physiological index monitoring method and system based on wireless earphone
CN203290879U (en) Monitor with urine test part
HU200272B (en) Method and instrument for external measuring of uterus retractions
CN203935172U (en) Skin oil and fat transfer printing probe and skin oil and fat secretion measuring device
CN2170075Y (en) Monitoring device for blood oxygen and blood pressure of external counterpulsaton
CN219538309U (en) Blood sugar detection circuit and blood sugar detection system

Legal Events

Date Code Title Description
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C06 Publication
PB01 Publication
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication