CN110433052A - The fat method of Hyperbaric Oxygen for Treatment high fat diet induction - Google Patents

The fat method of Hyperbaric Oxygen for Treatment high fat diet induction Download PDF

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Publication number
CN110433052A
CN110433052A CN201910778190.2A CN201910778190A CN110433052A CN 110433052 A CN110433052 A CN 110433052A CN 201910778190 A CN201910778190 A CN 201910778190A CN 110433052 A CN110433052 A CN 110433052A
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China
Prior art keywords
fat
hyperbaric
oxygen
high fat
10min
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Pending
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CN201910778190.2A
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Chinese (zh)
Inventor
袁骏华
董静
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Qingdao University
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Qingdao University
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Priority to CN201910778190.2A priority Critical patent/CN110433052A/en
Publication of CN110433052A publication Critical patent/CN110433052A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61GTRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G10/00Treatment rooms or enclosures for medical purposes
    • A61G10/02Treatment rooms or enclosures for medical purposes with artificial climate; with means to maintain a desired pressure, e.g. for germ-free rooms
    • A61G10/023Rooms for the treatment of patients at over- or under-pressure or at a variable pressure
    • A61G10/026Rooms for the treatment of patients at over- or under-pressure or at a variable pressure for hyperbaric oxygen therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61GTRANSPORT, PERSONAL CONVEYANCES, OR ACCOMMODATION SPECIALLY ADAPTED FOR PATIENTS OR DISABLED PERSONS; OPERATING TABLES OR CHAIRS; CHAIRS FOR DENTISTRY; FUNERAL DEVICES
    • A61G2210/00Devices for specific treatment or diagnosis

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  • Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses the fat methods of Hyperbaric Oxygen for Treatment high fat diet induction, and boost phase: average rate boosts to 1.8-2.0ATA in 5-10min;The pressure stabilizing stage: 50-70min, 1.8-2.2ATA;Buck stage: average rate drops to normal pressure in 5-10min;100% oxygen is supplied in cabin, hyperbaric oxygentherapy 1 time a day continues 3-4 weeks.The beneficial effects of the invention are as follows the intake of high fat diet after hyperbaric oxygentherapy in 3 weeks, is reduced, Energy intaking is reduced, reduces visceral fat weight and fat drips diameter, is lost weight.Increase brown fat, increases energy output.

Description

The fat method of Hyperbaric Oxygen for Treatment high fat diet induction
Technical field
The invention belongs to health care technology field, be related to it is a kind of using hyperbaric oxygen ation, adjuvant treatment high fat diet induction Fat correlation, which is ingested, to be increased, the method for fat drips deposition and weight gain.
Background technique
Obesity is not only mankind's public health problem of global range, and 2018, fat association was defined as one kind Disease.Fat early period and the fat occurrence and development that can dramatically increase more than 200 kinds of chronic diseases: compared with ideal body weight, moderate fertilizer Fat person's diabetes prevalence is 10 times of normal type, and severe obesity illness rate may be up to 30 times.In addition, overweight or fat meeting Increase metabolic syndrome, cardiovascular disease, respiratory disorder, fatty liver, dysgenesia, depression and kinds of tumor risk, very The risk that children suffer from diabetes, cardiovascular disease, cancer and Stein-Leventhal syndrome can extremely be increased.With the improvement of living standards Speeded with rhythm, people from low nutrition, high heat instant food and drink in the energy taken in increasingly increase, especially high-carbon hydrate Object (cake, biscuit, pie, Pizza) and high sugar food (candy, cola drink).These foods account for adult gross energy intake respectively 36% and children's gross energy intake 41%, account for the 41% and 47% of the total fat intake of children.United States Department of Agriculture's report claims, In In past 50 years, soft drink consumption amount increases nearly 500% per capita.It is opposite with Energy intaking is increased, cause fat increased another One factor is due to depending on the daily energy consumption of the vehicles and laborsaving equipment limit unduly.However, not having at present The specific medicament for having treatment fat is mainly that strict control of diet and increase move for this way to solve the problem.But High glucose and high fat food can activate the award access of central nervous system, cause " food is addicted ", increase obese patient's feed constantly Add and more have a preference for energy-dense foods, this pathophysiological mechanism becomes the serious obstruction of self diet control.On the other hand, long The operating mode of seat depends on the daily energy consumption of the vehicles and laborsaving equipment limit, tired out and work pressure unduly Power is a reason of limitation movement.Although strict control of diet and persistent movement can assist obesity controlling, compliance is poor, Slow effect and it is also easy to produce long-term resentment, therefore is badly in need of a kind of new method that adjuvant treatment is fat.Hyperbaric oxygen ation (HBO) is A technique for it is widely used in treating decompression sickness, air embolism and anthracemia, refers to that patient is being higher than 1 atmospheric pressure In environment, the therapeutic scheme of 100% oxygen is breathed.It is chronic refractory in recent years used also as including impaired graft and flap The adjuvant treatment of property osteomyelitis and diabetic foot ulcer.And hyperbaric oxygen ation is still blank in the application of fat auxiliary therapeutic area, The present invention provides a kind of weight-reducing physical therapy for not needing to keep on a diet, adjuvant treatment obesity and pre- preventing obesity are related concurrent Disease provides a kind of new application of hyperbaric oxygentherapy application.It there is no weight-reducing specific drug at present, strict control feed limits energy It takes in and adheres to moving, the method compliance for increasing energy output is poor.It is badly in need of the new assistance control Energy intaking of one kind at present simultaneously Increase power consumption methodology, does not need patient and lean on the stringent diet control of willpower, the object for not needing positive motion and taking drugs Physical therapy method.
Summary of the invention
The purpose of the present invention is to provide the fat methods of Hyperbaric Oxygen for Treatment high fat diet induction, and of the invention is beneficial After effect is hyperbaric oxygentherapy in 3 weeks, the intake of high fat diet is reduced, reduces Energy intaking, reduces visceral fat weight and rouge Diameter is dripped, is lost weight.Increase brown fat, increases energy output.
The technical scheme adopted by the invention is that boost phase: average rate boosts to 1.8-2.0ATA in 5-10min;Pressure stabilizing rank Section: 50-70min, 1.8-2.2ATA;Buck stage: average rate drops to normal pressure in 5-10min;100% oxygen is supplied in cabin, 1 time a day Hyperbaric oxygentherapy continues 3-4 weeks.
Detailed description of the invention
Fig. 1 is the obese model of high fat diet induction;
Fig. 2 is experiment mouse figure;
Fig. 3 is influence of the different length hyperbaric oxygentherapy period to weight;
Fig. 4 is the influence after hyperbaric oxygentherapy to visceral fat weight;
Fig. 5 is the influence after hyperbaric oxygentherapy to epididymal adipose tissues fat drips size.
Specific embodiment
The present invention is described in detail With reference to embodiment.
The present invention program is as follows:
Boost phase: average rate boosts to 1.8-2.0ATA in 5-10min
The pressure stabilizing stage: 50-70min, 1.8-2.2ATA
Buck stage: average rate drops to normal pressure in 5-10min
100% oxygen is supplied in cabin,
Hyperbaric oxygentherapy 1 time a day continues 3-4 weeks.
Experimental verification:
1. high fat diet inducing obesity model foundation: C57BL/6J mouse is randomly divided into two groups, feeds normal diet respectively (CD) and 45% high fat diet (HFD) obese model (Fig. 1) of high fat diet induction, is successfully established after 8 weeks, normal mouse is living Jump, obesity mice roll up lazy move (Fig. 2).
2. influence of the different length hyperbaric oxygentherapy period to weight: after the obese model of building high fat diet induction, with Machine is divided into normal diet group (CD);Normal diet+hyperbaric oxygen group (CD+HBO);High fat diet group (HFD);High fat diet+high pressure Four groups of oxygen group (HFD+HBO) was adapted to by one week environment, started to carry out hyperbaric oxygentherapy, respectively in 1,2,3,4 end cycle When survey weight (Fig. 3).
3. the influence to food-intake and Energy intaking: ingesting and measure the same day, fasting 12h after assessment hyperbaric oxygentherapy 3 weeks, Food is given after hyperbaric oxygentherapy, measures 1,2,3 hours accumulation food rations, and match according to normal diet and the energy of high fat diet Than calculating cumlative energy intake.
4. to the influence of visceral fat weight after hyperbaric oxygentherapy: after carrying out hyperbaric oxygentherapy in 4 weeks, taking kidney Zhou Baise rouge Fat, measures weight, and assessment hyperbaric oxygen influences (Fig. 4) on it.
5. the influence (Fig. 5) after hyperbaric oxygentherapy to epididymal adipose tissues fat drips size.
6. the influence after hyperbaric oxygentherapy to heat production tissue brown fat: after hyperbaric oxygentherapy, brown fat color burn, Brown fat caused by high fat diet " white esterification " reduces.
The above is only not to make limit in any form to the present invention to better embodiment of the invention System, any simple modification that embodiment of above is made according to the technical essence of the invention, equivalent variations and modification, Belong in the range of technical solution of the present invention.

Claims (1)

1. the fat method of Hyperbaric Oxygen for Treatment high fat diet induction, it is characterised in that:
Boost phase: average rate boosts to 1.8-2.0ATA in 5-10min;The pressure stabilizing stage: 50-70min, 1.8-2.2ATA;Decompression Stage: average rate drops to normal pressure in 5-10min;100% oxygen is supplied in cabin, hyperbaric oxygentherapy 1 time a day continues 3-4 weeks.
CN201910778190.2A 2019-08-22 2019-08-22 The fat method of Hyperbaric Oxygen for Treatment high fat diet induction Pending CN110433052A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910778190.2A CN110433052A (en) 2019-08-22 2019-08-22 The fat method of Hyperbaric Oxygen for Treatment high fat diet induction

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201910778190.2A CN110433052A (en) 2019-08-22 2019-08-22 The fat method of Hyperbaric Oxygen for Treatment high fat diet induction

Publications (1)

Publication Number Publication Date
CN110433052A true CN110433052A (en) 2019-11-12

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CN201910778190.2A Pending CN110433052A (en) 2019-08-22 2019-08-22 The fat method of Hyperbaric Oxygen for Treatment high fat diet induction

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022011052A1 (en) * 2020-07-08 2022-01-13 Curiel Gabriel Pressure differential-, ultrasound-, and magnetic-based methods for treating viral infections and other pathogenic diseases, sterilizing medical equipment, and enhancing fatty tissue reduction

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022011052A1 (en) * 2020-07-08 2022-01-13 Curiel Gabriel Pressure differential-, ultrasound-, and magnetic-based methods for treating viral infections and other pathogenic diseases, sterilizing medical equipment, and enhancing fatty tissue reduction

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Application publication date: 20191112

RJ01 Rejection of invention patent application after publication