CN110432269B - Stable peroxyacetic acid disinfectant and preparation method thereof - Google Patents
Stable peroxyacetic acid disinfectant and preparation method thereof Download PDFInfo
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- CN110432269B CN110432269B CN201910745088.2A CN201910745088A CN110432269B CN 110432269 B CN110432269 B CN 110432269B CN 201910745088 A CN201910745088 A CN 201910745088A CN 110432269 B CN110432269 B CN 110432269B
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/24—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients to enhance the sticking of the active ingredients
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group; Thio analogues thereof
Abstract
The invention discloses a stable peroxyacetic acid disinfectant and a preparation method thereof, belonging to the technical field of disinfectants. The invention discloses a stable peroxyacetic acid disinfectant, which is prepared from the following raw materials in parts by weight: 4-6 parts of persulfate, 2-5 parts of organic zinc, 3-5 parts of sepiolite, 15-30 parts of peroxyacetic acid, 3-5 parts of glacial acetic acid, 0.6-0.8 part of surfactant and 200-300 parts of gelatin dispersion liquid; the preparation method comprises the following steps of sequentially adding persulfate, organic zinc, sepiolite, peracetic acid, glacial acetic acid and a surfactant into a gelatin dispersion liquid at the temperature of 40-50 ℃ during preparation, adjusting the pH to the isoelectric point of gelatin after the addition is finished, carrying out ultrasonic dispersion, refrigerating at the temperature of 0-6 ℃ for 8-12 hours, discharging, and carrying out sealed storage to obtain the stable peroxyacetic acid disinfectant.
Description
Technical Field
The invention discloses a stable peroxyacetic acid disinfectant and a preparation method thereof, belonging to the technical field of disinfectants.
Background
Peracetic acid (PAA) disinfectant is used as a disinfectant with the advantages of high efficiency, broad spectrum, safety, no residual pollutants and the like, is applied in the field of domestic and foreign disinfection for more than half a century, and plays an important role in the aspects of prevention and control of infectious diseases and hospital infection, hygiene and preservation of food processing industry and the like. In recent years, the application of peracetic acid in the disinfection of special medical instruments, such as soft endoscopes, hemodialysis systems, epidemic areas, pipelines of food processing enterprises, aseptic packages, fields and the like, in medical institutions is continuously expanded, and research documents are continuously increased. The peracetic acid disinfectant has the advantages of high efficiency, broad spectrum, safety, no secondary pollution and the like, can be widely used for disinfecting the surfaces of articles, livestock and poultry aquaculture industry, food processing industry, hospitals and public spaces, and plays an important role in preventing and controlling serious epidemic diseases. In the countries of the Europe and America, the primary peroxyacetic acid disinfectant products of a plurality of companies are applied to high-level disinfection of clinical samples, medical instruments (such as endoscopes, hemodiascopes and the like), and the like, such as Solvay, olympus and the like. Due to the defects of complex operation, unstable content and the like of the binary peroxyacetic acid disinfectant, new requirements and opportunities are provided for developing a binary peroxyacetic acid disinfectant product with good sterilization effect, controllable metal corrosivity and strong stability.
In order to prolong the stability of the primary peroxyacetic acid disinfectant, at present, a stabilizer is generally added into the disinfectant, for example, a hydrolyzed maleic anhydride copolymer and phosphide compound, 8-hydroxyquinoline and the like are added into a product to increase the stability, but because the hydrolyzed maleic anhydride copolymer and phosphide compound need to be prepared by self, the process, the quality and the proportion of the hydrolyzed maleic anhydride copolymer become another difficulty to be solved, and bring certain difficulty to the actual production, while the 8-hydroxyquinoline is proved to be a carcinogenic substance, and is forbidden to be used as the stabilizer of the disinfectant in some countries in Europe.
Disclosure of Invention
Aiming at the defect that the stability of the commonly adopted peroxyacetic acid disinfectant in the storage process is poor so that the disinfection capability of a disinfectant product after long-term storage is reduced, the invention provides a stable peroxyacetic acid disinfectant and a preparation method thereof.
In order to achieve the purpose, the invention provides a stable peracetic acid disinfectant, which comprises the following raw materials in parts by weight:
4-6 parts of persulfate
2-5 parts of organic zinc
3-5 parts of sepiolite
15-30 parts of peroxyacetic acid
3-5 parts of glacial acetic acid
0.6-0.8 part of surfactant
200-300 parts of gelatin dispersion
Further, the stable peroxyacetic acid disinfectant comprises the following raw materials in parts by weight:
5-6 parts of persulfate
2-4 parts of organic zinc
4-5 parts of sepiolite
25-30 parts of peroxyacetic acid
3-4 parts of glacial acetic acid
0.7-0.8 part of surfactant
250-300 parts of gelatin dispersion liquid
The beneficial effects are that:
according to the technical scheme, a gel system is constructed by adopting the gelatin dispersion liquid, the surfactant, the sepiolite, the organic zinc, the persulfate and other auxiliaries together, the peracetic acid component distributed in a liquid state in the system can be effectively limited in the gel framework due to the existence of the gel framework, the activity of the peracetic acid is effectively limited, each gel framework unit forms chemical dynamic balance, even if the chemical dynamic balance of part of the framework units is damaged, the similar units can be quickly supplemented, the organic zinc and persulfate are difficult to instantly diffuse to the whole network framework of the system, and the stability of the whole system is ensured.
Further, the persulfate is any one of potassium persulfate, sodium persulfate and ammonium persulfate.
The beneficial effects are that:
according to the technical scheme, the persulfate is added, the persulfate and the peroxyacetic acid are utilized to generate a synergistic interaction effect, in addition, an ionization system of the persulfate and an ionization system of the peroxyacetic acid can well coexist and cannot interfere with each other, and the adverse effect on the stability of the peroxyacetic acid is effectively avoided.
Further, the organic zinc is: any one of zinc citrate and zinc gluconate.
The beneficial effects are that:
according to the technical scheme, organic zinc is introduced into the system, the organic zinc and other components in the system form interaction, zinc ions can form chelation with carboxylate ions generated by ionization of peracetic acid and the like in the system, and citric acid groups or gluconic acid groups and gelatin molecules can jointly construct a gel network system, so that active molecule chain segments of peracetic acid are effectively limited in the gel network structure in the long-term storage process of products, and a good stabilizing effect is achieved.
Further, the sepiolite is acid modified sepiolite; the modification process of the acid modified sepiolite comprises the following steps: mixing sepiolite and a strong acid solution according to a mass ratio of 1: 5-1: and (3) after ultrasonic dispersion, carrying out hydrothermal stirring reaction, filtering, washing, drying and roasting to obtain the acid modified sepiolite.
Further, the strong acid solution is 1-10% by mass; the strong acid is any one of hydrochloric acid, sulfuric acid or nitric acid.
Further, the hydrothermal stirring reaction comprises the following steps: and carrying out hydrothermal stirring reaction for 1-6 h at the temperature of 160-180 ℃, the pressure of 2.0-6.0 MPa and the stirring speed of 200-600 r/min.
The beneficial effects are that:
according to the technical scheme, the sepiolite is introduced, firstly, the thickening performance of the sepiolite is utilized, the stability of the product in the standing process is improved, the situation that peracetic acid is separated from a gel structure due to phase separation of a system is avoided, in addition, impurity metal ions in the molecular structure of the sepiolite are replaced by hydrogen ions in strong acid, the adverse effect of the introduction of the impurity metal ions on the stability of the peracetic acid is avoided, meanwhile, the interlayer spacing of the sepiolite with a sheet structure is effectively widened by utilizing a hydrothermal reaction, so that the system has good rheological performance and dilution collapsibility, the rapid dispersion of the sepiolite can be guaranteed only by adding water for dilution and matching with a shearing acting force with certain strength when the sepiolite is used, and the use convenience of the product is guaranteed.
Further, the surfactant is any one of octane sodium sulfonate, sodium dodecyl benzene sulfonate, sodium dodecyl toluene sulfonate, sodium dodecyl xylene sulfonate, sodium dodecyl sulfate and sodium hexadecyl benzene sulfonate.
The beneficial effects are that:
the introduction of the surfactant can also play a role in improving the compatibility of the sepiolite and the gel network system.
Further, the gelatin dispersion liquid is prepared from gelatin with an isoelectric point of 5.5-6.0 and water according to a mass ratio of 1: 10-1: 30 are mixed together.
In order to achieve the purpose of the invention, the invention also provides a method for preparing the stable peroxyacetic acid disinfectant, which comprises the following steps:
weighing the components according to the composition of the raw materials;
sequentially adding persulfate, organic zinc, sepiolite, peracetic acid, glacial acetic acid and a surfactant into the gelatin dispersion liquid at the temperature of 40-50 ℃, adjusting the pH to the isoelectric point of gelatin after the addition is finished, refrigerating for 8-12 h at the temperature of 0-6 ℃ after ultrasonic dispersion, discharging, sealing and storing to obtain the stable peracetic acid disinfectant.
The beneficial effects are that:
the gelatin is firstly mixed under certain stability, in the mixing process, due to the existence of ingredients such as peracetic acid, glacial acetic acid and the like, a system deviates from the isoelectric point (pH is lower than 6.0) of the original gelatin, after the gelatin deviates from the isoelectric point, amino groups in a molecular structure of the gelatin are positively charged under the action of hydrogen ions, due to the repulsion action among the same charges, the molecular structure of the gelatin is fully expanded to adsorb other components in the system, and then in the process of adjusting the gelatin back to the isoelectric point, the molecular structure of the gelatin is electrically neutral to cause molecular shrinkage, a casting forms gel in the refrigeration process, and the adsorbed other components are effectively limited in a gel network framework, so that a good stabilizing effect is achieved.
Detailed Description
The following is a detailed description of embodiments of the invention, but the invention can be implemented in many different ways, as defined and covered by the claims.
Example 1
Acid-modified sepiolite: according to the mass ratio of 1: 10, mixing sepiolite and hydrochloric acid solution with the mass fraction of 5% and pouring the mixture into a hydrothermal reaction kettle, performing ultrasonic dispersion for 80min under the condition that the ultrasonic frequency is 65kHz to obtain sepiolite dispersion liquid, pouring the sepiolite dispersion liquid into the hydrothermal reaction kettle, performing hydrothermal stirring reaction for 3h under the conditions that the temperature is 170 ℃, the pressure is 4.0MPa and the stirring speed is 300r/min, filtering the materials in the hydrothermal reaction kettle to obtain filter residue, washing the filter residue with deionized water until the washing liquid is neutral, drying the washed filter residue to constant weight under the condition that the temperature is 100 ℃ to obtain dried filter residue, transferring the dried filter residue into a roasting furnace, roasting for 3h under the condition that the temperature is 250 ℃, cooling, and discharging to obtain acid-modified sepiolite;
gelatin dispersion liquid: gelatin with isoelectric point of 5.8 and water are mixed according to the mass ratio of 1: 20, standing and swelling for 6 hours after mixing, and heating, stirring and dissolving at the temperature of 75 ℃ and the stirring speed of 300r/min to obtain a gelatin dispersion liquid;
peroxyacetic acid disinfectant: according to the weight parts, 6 parts of sodium persulfate, 4 parts of zinc citrate, 5 parts of acid modified sepiolite, 30 parts of peroxyacetic acid, 4 parts of glacial acetic acid, 0.8 part of sodium dodecyl benzene sulfonate and 280 parts of gelatin dispersion liquid are taken in sequence, the gelatin dispersion liquid is poured into a container, the container is placed in a digital display speed measurement constant temperature magnetic stirrer with the temperature of 50 ℃, sodium persulfate, zinc citrate, acid modified sepiolite, peroxyacetic acid, glacial acetic acid and sodium dodecyl benzene sulfonate are sequentially added into the container under the constant temperature stirring state, after the adding is finished, the pH value of materials in the container is adjusted to 5.8, the container is sealed, ultrasonic dispersion is carried out for 60min under the ultrasonic frequency of 60kHz, the container is moved into the environment with the temperature of 4 ℃ for refrigeration for 12h, discharging, filling and sealing are carried out, and the stable peroxyacetic acid disinfectant is obtained.
The product obtained in example 1 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test is carried out on the product obtained in example 1, and the product obtained by the invention is diluted to the concentration of 0.1 percent (mass fraction of peroxyacetic acid), so that the uniform bactericidal effect is achieved under the condition that the concentration of the commercial binary packaged peroxyacetic acid is 1.8 percent.
Example 2
Acid-modified sepiolite: according to the mass ratio of 1: 5, mixing sepiolite and hydrochloric acid solution with the mass fraction of 1% and pouring the mixture into a hydrothermal reaction kettle, performing ultrasonic dispersion for 40min under the condition that the ultrasonic frequency is 45kHz to obtain sepiolite dispersion liquid, pouring the sepiolite dispersion liquid into the hydrothermal reaction kettle, performing hydrothermal stirring reaction for 1h under the conditions that the temperature is 160 ℃, the pressure is 2.0MPa and the stirring speed is 200r/min, filtering the materials in the hydrothermal reaction kettle to obtain filter residue, washing the filter residue with deionized water until the washing liquid is neutral, drying the washed filter residue to constant weight under the condition that the temperature is 100 ℃ to obtain dried filter residue, transferring the dried filter residue into a roasting furnace, roasting for 2h under the condition that the temperature is 240 ℃, cooling, and discharging to obtain acid-modified sepiolite;
gelatin dispersion liquid: gelatin with isoelectric point of 5.5 and water are mixed according to the mass ratio of 1: 10, standing and swelling for 6 hours after mixing, and heating, stirring and dissolving at the temperature of 75 ℃ and the stirring speed of 300r/min to obtain a gelatin dispersion liquid;
peroxyacetic acid disinfectant: according to the weight parts, 4 parts of sodium persulfate, 2 parts of zinc citrate, 3 parts of acid modified sepiolite, 15 parts of peroxyacetic acid, 3 parts of glacial acetic acid, 0.6 part of sodium dodecyl benzene sulfonate and 200 parts of gelatin dispersion liquid are taken in sequence, the gelatin dispersion liquid is poured into a container, the container is placed in a digital display speed measurement constant temperature magnetic stirrer with the temperature of 50 ℃, sodium persulfate, zinc citrate, acid modified sepiolite, peroxyacetic acid, glacial acetic acid and sodium dodecyl benzene sulfonate are sequentially added into the container under the constant temperature stirring state, after the adding is finished, the pH value of materials in the container is adjusted to 5.5, the container is sealed, ultrasonic dispersion is carried out for 60min under the ultrasonic frequency of 60kHz, the container is moved into the environment with the temperature of 4 ℃ for refrigeration for 12h, discharging, filling and sealing are carried out, and the stable peroxyacetic acid disinfectant is obtained.
The product obtained in example 2 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test of the product obtained in example 2 shows that the product obtained by the invention is diluted to the concentration of 0.15% (mass fraction of peroxyacetic acid), so that the uniform bactericidal effect of the commercial binary packaged peroxyacetic acid under the condition of 1.8% concentration is achieved.
Example 3
Acid-modified sepiolite: according to the mass ratio of 1: 20, mixing sepiolite and hydrochloric acid solution with the mass fraction of 10% and pouring the mixture into a hydrothermal reaction kettle, performing ultrasonic dispersion for 120min under the condition that the ultrasonic frequency is 80kHz to obtain sepiolite dispersion liquid, pouring the sepiolite dispersion liquid into the hydrothermal reaction kettle, performing hydrothermal stirring reaction for 6h under the conditions that the temperature is 180 ℃, the pressure is 6.0MPa and the stirring speed is 600r/min, filtering the materials in the hydrothermal reaction kettle to obtain filter residue, washing the filter residue with deionized water until the washing liquid is neutral, drying the washed filter residue to constant weight under the condition that the temperature is 100 ℃ to obtain dried filter residue, transferring the dried filter residue into a roasting furnace, roasting for 6h under the condition that the temperature is 290 ℃, cooling and discharging to obtain acid-modified sepiolite;
gelatin dispersion liquid: gelatin with isoelectric point of 6.0 and water are mixed according to the mass ratio of 1: 30, standing and swelling for 6 hours, and heating, stirring and dissolving at the temperature of 75 ℃ and the stirring speed of 300r/min to obtain a gelatin dispersion liquid;
peroxyacetic acid disinfectant: according to the weight parts, 6 parts of sodium persulfate, 5 parts of zinc citrate, 5 parts of acid modified sepiolite, 30 parts of peroxyacetic acid, 5 parts of glacial acetic acid, 0.8 part of sodium dodecyl benzene sulfonate and 300 parts of gelatin dispersion liquid are taken in sequence, the gelatin dispersion liquid is poured into a container, the container is placed in a digital display speed measurement constant temperature magnetic stirrer with the temperature of 50 ℃, sodium persulfate, zinc citrate, acid modified sepiolite, peroxyacetic acid, glacial acetic acid and sodium dodecyl benzene sulfonate are sequentially added into the container under the constant temperature stirring state, after the adding is finished, the pH value of materials in the container is adjusted to 6.0, the container is sealed, ultrasonic dispersion is carried out for 60min under the ultrasonic frequency of 60kHz, the container is moved into the environment with the temperature of 4 ℃ for refrigeration for 12h, discharging, filling and sealing are carried out, and the stable peroxyacetic acid disinfectant is obtained.
The product obtained in example 3 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test is carried out on the product obtained in the example 3, and the product obtained by the invention is diluted to the concentration of 0.09% (mass fraction of peroxyacetic acid), so that the uniform bactericidal effect is achieved under the condition that the concentration of the commercial binary packaged peroxyacetic acid is 1.8%.
Example 4
The present embodiment is different from embodiment 1 in that:
the sepiolite is not subjected to acid modification and is directly used; the other components are the same and the same processing technology is adopted;
the product obtained in example 4 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test is carried out on the product obtained in the example 4, and the product obtained by the invention is diluted to the concentration of 0.3 percent (mass fraction of peroxyacetic acid), so that the consistent bactericidal effect is achieved under the condition that the concentration of the commercial binary packaged peroxyacetic acid is 1.8 percent.
Example 5
The present embodiment is different from embodiment 1 in that:
peroxyacetic acid disinfectant: according to the weight parts, 4 parts of zinc citrate, 5 parts of acid modified sepiolite, 30 parts of peracetic acid, 4 parts of glacial acetic acid, 0.8 part of sodium dodecyl benzene sulfonate and 280 parts of gelatin dispersion liquid are taken in sequence, the gelatin dispersion liquid is poured into a container, the container is placed in a digital display speed measurement constant temperature magnetic stirrer with the temperature of 50 ℃, zinc citrate, acid modified sepiolite, peracetic acid, glacial acetic acid and sodium dodecyl benzene sulfonate are sequentially added into the container under the constant temperature stirring state, after the adding is finished, the pH value of materials in the container is adjusted to 5.8, the container is sealed, the materials are ultrasonically dispersed for 60min under the ultrasonic frequency of 60kHz, the container is moved into the environment with the temperature of 4 ℃ for refrigeration for 12h, the materials are discharged, and the stable peroxyacetic acid disinfectant is obtained after filling and sealing.
The product obtained in example 5 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test of the product obtained in example 5 shows that the product obtained by the invention is diluted to the concentration of 0.4% (mass fraction of peroxyacetic acid), so that the uniform bactericidal effect of the commercial binary packaged peroxyacetic acid under the condition of 1.8% concentration is achieved.
Example 6
The present embodiment is different from embodiment 1 in that:
peroxyacetic acid disinfectant: according to the weight parts, 6 parts of sodium persulfate, 5 parts of acid modified sepiolite, 30 parts of peracetic acid, 4 parts of glacial acetic acid, 0.8 part of sodium dodecyl benzene sulfonate and 280 parts of gelatin dispersion liquid are taken in sequence, the gelatin dispersion liquid is poured into a container, the container is placed in a digital display speed measurement constant temperature magnetic stirrer with the temperature of 50 ℃, the sodium persulfate, the acid modified sepiolite, the peroxyacetic acid, the glacial acetic acid and the sodium dodecyl benzene sulfonate are sequentially added into the container under the constant temperature stirring state, after the adding is finished, the pH value of materials in the container is adjusted to 5.8, the container is sealed, the materials are ultrasonically dispersed for 60min under the ultrasonic frequency of 60kHz, the container is moved into the environment with the temperature of 4 ℃ for refrigeration for 12h, the materials are discharged, and the stable peroxyacetic acid disinfectant is obtained after filling and sealing.
The product obtained in example 6 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test of the product obtained in example 6 shows that the product obtained by the invention is diluted to the concentration of 0.4% (mass fraction of peroxyacetic acid), so that the uniform bactericidal effect of the commercial binary packaged peroxyacetic acid under the condition of 1.8% concentration is achieved.
Example 7
The present embodiment is different from embodiment 1 in that:
peroxyacetic acid disinfectant: according to the weight parts, 6 parts of sodium persulfate, 4 parts of zinc citrate, 5 parts of acid modified sepiolite, 30 parts of peroxyacetic acid, 4 parts of glacial acetic acid, 0.8 part of sodium dodecyl benzene sulfonate and 280 parts of water are taken in sequence, the water is poured into a container, the container is placed in a digital display speed measurement constant temperature magnetic stirrer with the temperature of 50 ℃, the sodium persulfate, the zinc citrate, the acid modified sepiolite, the peroxyacetic acid, the glacial acetic acid and the sodium dodecyl benzene sulfonate are sequentially added into the container under the constant temperature stirring state, after the adding is finished, the pH value of materials in the container is adjusted to 5.8, the container is sealed, the materials are ultrasonically dispersed for 60min under the ultrasonic frequency of 60kHz, the container is moved into the environment with the temperature of 4 ℃ for refrigeration for 12h, the discharging is carried out, and the stable peroxyacetic acid disinfectant is obtained after filling and sealing.
The product obtained in example 7 was stored at a constant temperature of 55 ℃ for a certain period of time, and the decrease rate of peracetic acid was measured, and the measurement results are shown in the following table:
in addition, the bactericidal rate test of the product obtained in example 7 shows that the product obtained by the invention is diluted to the concentration of 0.45% (mass fraction of peroxyacetic acid), so that the uniform bactericidal effect of the commercial binary packaged peroxyacetic acid under the condition of 1.8% concentration is achieved.
Claims (4)
1. The stable peroxyacetic acid disinfectant is characterized by comprising the following raw materials in parts by weight:
4-6 parts of persulfate;
2-5 parts of organic zinc;
3-5 parts of sepiolite;
15-30 parts of peroxyacetic acid;
3-5 parts of glacial acetic acid;
0.6-0.8 part of surfactant;
200-300 parts of gelatin dispersion liquid;
the persulfate is any one of potassium persulfate, sodium persulfate or ammonium persulfate;
the organic zinc is as follows: any one of zinc citrate or zinc gluconate;
the sepiolite is acid modified sepiolite; the modification process of the acid modified sepiolite comprises the following steps: mixing sepiolite and a strong acid solution according to a mass ratio of 1: 5-1: after 20 ultrasonic dispersion, carrying out hydrothermal stirring reaction, filtering, washing, drying and roasting to obtain acid modified sepiolite;
the hydrothermal stirring reaction comprises the following steps: carrying out hydrothermal stirring reaction for 1-6 h at the temperature of 160-180 ℃, the pressure of 2.0-6.0 MPa and the stirring speed of 200-600 r/min;
the gelatin dispersion liquid is prepared from gelatin with an isoelectric point of 5.5-6.0 and water according to a mass ratio of 1: 10-1: 30 are mixed together.
2. A peroxyacetic acid disinfectant as set forth in claim 1 wherein: the strong acid solution is 1-10% by mass; the strong acid is any one of hydrochloric acid, sulfuric acid or nitric acid.
3. A peroxyacetic acid disinfectant as set forth in claim 2 wherein: the surfactant is:
octane sodium sulfonate, dodecyl sodium benzene sulfonate, dodecyl sodium sulfonate, dodecyl benzene sulfonic acid sodium salt, dodecyl toluene sulfonic acid sodium salt, dodecyl xylene sulfonic acid sodium salt, dodecyl sodium sulfate, and hexadecyl sodium benzene sulfonate.
4. A method of formulating the stabilized peracetic acid disinfectant of claim 1, wherein the formulating process comprises:
weighing the components according to the composition of the raw materials;
sequentially adding persulfate, organic zinc, sepiolite, peracetic acid, glacial acetic acid and a surfactant into the gelatin dispersion liquid at the temperature of 40-50 ℃, adjusting the pH to the isoelectric point of gelatin after the addition is finished, refrigerating for 8-12 h at the temperature of 0-6 ℃ after ultrasonic dispersion, discharging, sealing and storing to obtain the stable peracetic acid disinfectant.
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