CN1104247C - Suppository for treating cervical erosion and vaginitis - Google Patents

Suppository for treating cervical erosion and vaginitis Download PDF

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Publication number
CN1104247C
CN1104247C CN00123869A CN00123869A CN1104247C CN 1104247 C CN1104247 C CN 1104247C CN 00123869 A CN00123869 A CN 00123869A CN 00123869 A CN00123869 A CN 00123869A CN 1104247 C CN1104247 C CN 1104247C
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China
Prior art keywords
suppository
cervical erosion
honey
substrate
present
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Expired - Fee Related
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CN00123869A
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Chinese (zh)
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CN1286989A (en
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王双计
曹志向
刘光珍
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Individual
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Individual
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Abstract

The present invention relates to a suppository for treating cervical erosion and vaginitis, which is a medicament prepared by using phellodendron bark, zedoary, armstrong, dried alum, zanthoxylum bungeanum and honey as raw materials. The phellodendron bark, the zedoary, the armstrong, the dried alum and the zanthoxylum bungeanum are ground into fine powder; a mixture of glycerol, gelatin and distilled water is heated in a water bath to dissolve, and is used as a substrate; when the medicinal powder and the honey are heated, the medicinal powder and the honey are added into the substrate, and the suppository can be obtained by uniformly stirring, molding, naturally cooling, bagging, sealing and sterilizing. The suppository has the advantages of conspicuous curative effect, scientific and reasonable preparation process, short treatment course and no toxic or side effect, and can treat both the manifestation and the root cause of a disease. The clinical total effective rate of the suppository reaches more than 86%. The suppository is better than the congener medicine at present, and is good medicine for preventing and treating gynecopathy, such as cervical erosion, kysthitis, etc.

Description

A kind of treatment cervical erosion, colpitic suppository
The present invention relates to a kind of pharmaceutical composition for the treatment of gynaecopathia, particularly relate to a kind of with Chinese medicine be raw material make be used for the treatment of cervical erosion, colpitic suppository.
Cervical erosion, vaginitis are commonly encountered diseases, the frequently-occurring diseases of present gynecological.Especially cervical erosion, as can not get good treatment, part patient may develop into precancerous lesion, and is bigger to the harm of women's health.Therefore, how to prevent and treat this type of disease and become the problem that medical circle presses for solution.The method and the medicine of this class disease of treatment are more at present, as laser therapy, cold therapy, Chinese and western drugs oral administration and externally etc.But the problem owing to aspects such as whether curative effect, side effect and patient accept is applied it and is subjected to certain limitation, is badly in need of research and seeks a kind of safe, efficient, long lasting treatment medicine, to remove patient's body and mind misery.
The objective of the invention is to provide at above deficiency a kind of can antiinflammatory, antipruritic, pain relieving, improve blood circulation, that regulates immunity and endocrine function is used for the treatment of cervical erosion, colpitic suppository.
It is considered herein that such disease mainly is because intrusions such as pathogen staphylococcus, streptococcus, escherichia coli, mycete, infusorian, virus cause due to the infection.The clinical leucorrhoea grow in quantity that mainly shows as is equivalent to " leukorrheal diseases " " pudendal pruritus " of Chinese medicine etc.Therapeutic Principle of the present invention is " heat clearing and damp drying, parasite killing, putrefaction removing life, a blood-activating analgetic ", adopts heat clearing and damp drying, eliminating inflammation and expelling toxin, and anti-bacterial, anti-itching, methods such as microcirculation improvement and immunologic function have been developed treatment cervical erosion, colpitic suppository.This suppository is that the component with following proportioning by weight is the medicament that raw material is made:
Cortex Phellodendri 60~100g Rhizoma Curcumae 40~80g Herba Polygoni Avicularis 15~30g dried Alumen 10~20g Pericarpium Zanthoxyli 10~20g Mel 30~60g
Preparation method of the present invention is: above-mentioned Cortex Phellodendri, Rhizoma Curcumae, Herba Polygoni Avicularis, dried Alumen, Pericarpium Zanthoxyli ground spice are broken into fine powder; Get the mixture 300g of glycerol, gelatin, distilled water, the proportioning of glycerol, gelatin, distilled water is 70: 20: 10, and heating in water bath dissolves, and as substrate, temperature remains on 50 ℃ ± 2 ℃; Take advantage of heat to add in the substrate above-mentioned medicated powder and Mel, stir evenly, moulding, natural cooling, pack, sealing sterilization are promptly.
It is monarch that the present invention selects Cortex Phellodendri for use, heat clearing and damp drying, eliminating fire and detoxication, anti-inflammation; With Rhizoma Curcumae, Herba Polygoni Avicularis is minister, Rhizoma Curcumae promoting blood circulation and stopping pain, antiinflammatory, and microcirculation improvement is regulated immunologic function, suppresses cell mutation, the dehumidifying of Herba Polygoni Avicularis diuretic, detoxifcation, antiinflammatory; Assistant restrains dampness with dried Alumen, Pericarpium Zanthoxyli, Mel, killing parasites for relieving itching, and anti-inflammation, putrefaction-removing granulation-promoting reaches the effect of anti-inflammation, killing parasites for relieving itching, putrefaction-removing granulation-promoting, microcirculation improvement, adjusting immunologic function jointly.
Further describe the present invention below in conjunction with embodiment:
According to treatment cervical erosion, the colpitic suppository of the present invention preparation, its most preferred embodiment is that the component with following proportioning by weight is the medicament that raw material is made:
Cortex Phellodendri 80g Rhizoma Curcumae 60g Herba Polygoni Avicularis 20g dried Alumen 15g Pericarpium Zanthoxyli 15g Mel 40g
The present invention used this suppository treatment cervical erosion, vaginitis 50 examples from 1999 to 2000, and compared with BAOFUKANG SHUAN 20 examples, and BAOFUKANG SHUAN is to be produced by Bikai Pharmaceutics Co., Hainan prov..Treatment cervical erosion, colpitic suppository that the treatment group is used are to be processed according to suppository pharmaceutical production technology in the provisions for new drugs approval and quality standard requirement by the kind together Pharma Inc. in Taiyuan, Shanxi Province according to prescription of the present invention, and the rotten health of tentative woman by name is fastened.Administrated method be an order once, one time one, every night this bolt is pushed the vagina deep, 20 days is a course of treatment; Matched group in the same way, use BAOFUKANG SHUAN the identical course of treatment.Two groups all with single blind method administration at random, does the contrast summary after treat two courses of treatment.Observed result shows: treatment group clinical cure rate and total effective rate reach 42%, 86% respectively, and matched group then is respectively 15% and 16%, through Ridit statistical test P<0.05, two group significant difference are arranged.Confirm that the present invention treats diseases such as cervical erosion, vaginitis curative effect is preferably arranged, its effect is better than contrasting the medicine BAOFUKANG SHUAN, especially improve or eliminate such as leukorrhagia, scratch where it itches, effect is more obvious aspect the sings and symptoms such as pain.
Confirm that through animal experiment the present invention's medicine has significant antiinflammatory, antipruritic, pain relieving, effect such as antibacterial, (seeing the Pharmacodynamic test of active extract material that the rotten health of woman is fastened).Acute toxinology experiment confirmation this product is used and is not seen any toxic and side effects.Skin and mucous membrane irritation and hypersensitive test show that also this product is used for the vaginal mucosa place and does not have any stimulation and anaphylaxis.So the present invention's medicine is not only evident in efficacy, and safe and reliable.
In sum, short treating period of the present invention, evident in efficacy, with strong points, can treating both the principal and secondary aspects of a disease.Especially adopt the method for local patholoic change local application, the medicine disease institute that can go directly, the utilization rate of active components height, it is fast to play a role, the general curative effect height, and short-term and long-term efficacy are good, safe and reliable in addition, without any side effects, be better than present similar medicine, be the good medicine of preventing and treating gynecological diseases such as cervical erosion, vaginitis.Preparation technology of the present invention is scientific and reasonable, simple and easy to do, employing glycerol etc. is substrate, do not influence the absorption of effective ingredient, avoided simple employing water extraction to make water-fast effective ingredient be difficult to stripping simultaneously, the deficiency that volatile ingredient is easily lost, and organic solvent extraction makes effective ingredient soluble in water be difficult for the drawback of stripping.This process has guaranteed in the medicine that all effective ingredient are used as medicine to greatest extent, and portably uses very conveniently, has potential application and exploitation is worth.

Claims (3)

1, a kind of treatment cervical erosion, colpitic suppository is characterized in that it is that component with following proportioning by weight is the medicament that raw material is made:
Cortex Phellodendri 60~100g Rhizoma Curcumae 40~80g Herba Polygoni Avicularis 15~30g dried Alumen 10~20g Pericarpium Zanthoxyli 10~20g Mel 30~60g.
2, treatment cervical erosion according to claim 1, colpitic suppository is characterized in that it is that component with following proportioning by weight is the medicament that raw material is made:
Cortex Phellodendri 80g Rhizoma Curcumae 60g Herba Polygoni Avicularis 20g dried Alumen 15g Pericarpium Zanthoxyli 15g Mel 40g.
3, treatment cervical erosion according to claim 1, colpitic suppository is characterized in that preparation method is: above-mentioned Cortex Phellodendri, Rhizoma Curcumae, Herba Polygoni Avicularis, dried Alumen, Pericarpium Zanthoxyli ground spice are broken into fine powder; Get the mixture 300g of glycerol, gelatin, distilled water, the proportioning of glycerol, gelatin, distilled water is 70: 20: 10, and heating in water bath dissolves, and as substrate, temperature remains on 50 ℃ ± 2 ℃; Take advantage of heat to add in the substrate above-mentioned medicated powder and Mel, stir evenly, moulding, natural cooling, pack, sealing sterilization are promptly.
CN00123869A 2000-08-24 2000-08-24 Suppository for treating cervical erosion and vaginitis Expired - Fee Related CN1104247C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN00123869A CN1104247C (en) 2000-08-24 2000-08-24 Suppository for treating cervical erosion and vaginitis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN00123869A CN1104247C (en) 2000-08-24 2000-08-24 Suppository for treating cervical erosion and vaginitis

Publications (2)

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CN1286989A CN1286989A (en) 2001-03-14
CN1104247C true CN1104247C (en) 2003-04-02

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CN00123869A Expired - Fee Related CN1104247C (en) 2000-08-24 2000-08-24 Suppository for treating cervical erosion and vaginitis

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1325111C (en) * 2004-07-08 2007-07-11 黄文峰 Traditional Chinese medicine composition for treating colpitis and cervicitis, prepn. method and quality standard therefor

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1294946C (en) * 2003-01-06 2007-01-17 吴桂菊 Chinese medicine suppository for curing gynecopathy, and its preparing method and use method
ITRM20120555A1 (en) * 2012-11-13 2014-05-14 Aboca Spa Societa Agricola Enemas.
CN103445904B (en) * 2013-09-25 2015-05-13 桂林恒保健康用品有限公司 Condom capable of treating cervicitis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1325111C (en) * 2004-07-08 2007-07-11 黄文峰 Traditional Chinese medicine composition for treating colpitis and cervicitis, prepn. method and quality standard therefor

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