CN110420148A - A kind of lavender fermentation magma and its preparation method and application - Google Patents

A kind of lavender fermentation magma and its preparation method and application Download PDF

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Publication number
CN110420148A
CN110420148A CN201910839895.0A CN201910839895A CN110420148A CN 110420148 A CN110420148 A CN 110420148A CN 201910839895 A CN201910839895 A CN 201910839895A CN 110420148 A CN110420148 A CN 110420148A
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lavender
weight
magma
parts
preparation
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唐天涛
方晓薇
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Zhejiang Dameishi Network Technology Co Ltd
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Zhejiang Dameishi Network Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to skin care item to process field, more particularly to a kind of lavender fermentation magma and its preparation method and application.The present invention provides a kind of lavender fermentation magma, and raw material is grouped as by the group of following weight ratio: lavender pollen 6-8 parts by weight, pure water 70-85 parts by weight, saccharomyces cerevisiae 7-10 parts by weight.Preparation method, comprising the following steps: S1 chooses dry lavandulae flos, grinding and sieving；Lavender pollen, pure water, saccharomyces cerevisiae in step S1 is uniformly mixed by S2, keeps temperature 20-30 degree, stands 48-72 hours；S3 sterilizing inactivation；S4 centrifugation is removed slag；S5 is de-tasted；S5 adds preservative and retains.Lavender fermentation magma provided by the invention, not only remains the nutritional ingredient of lavender itself: total reducing sugar, total phenol, general flavone, polypeptide, also adds small molecule brought by microbial metabolic products and can absorb nutritional ingredient.Its skin-care nutrient ingredient is natural moisturizing factor, high with skin compatibility and be easy to be absorbed, and moisture can be locked in the cell and have moisture-keeping efficacy by the hydrophilic radicals such as contained amino, hydroxyl, carboxyl.

Description

A kind of lavender fermentation magma and its preparation method and application
Technical field
The present invention relates to skin care item to process field, more particularly to a kind of lavender fermentation magma and preparation method thereof And application.
Background technique
Lavender also known as vanilla, Lysimachia foenum-graecum belong to perennial half negative undershrub, originate in Mediterranean, be a kind of Precious spice crop.Any sweet substance, which is not added, in lavender jasmine tea can generate sweet mouthfeel, also have calm, clear Numerous effects such as cool, aid digestion, preventing cold.Lavender is rich in volatile oil, cumarin, tannin, flavonoids and a variety of pairs of human bodies Have the microelement etc. of important health-care effect, can be used for cooking, is medicinal, the various aspects such as beauty, have it is with all worries set aside calm the nerves, feelings of calming Thread treats the sense that lessens fatigue of having a sleepless night, and mitigates neuralgia and other effects.Skin is the pith for safeguarding human life and health, directly It connects and is contacted with the external world, be the first barrier of body, be highly prone to the influence of environmental factor and cause to damage.It protects currently on the market Skin product mostly use chemical synthesis substance to be formulated greatly, it is expensive and meanwhile also easily cause skin allergy, heavy metal accumulation, skin The side effects such as paraplasm.As being constantly progressive for social economy is goed deep into the abundant and research of material life, people disappear Water wasting is flat to be continuously improved, and the majority of consumers hold more careful attitude to the skin care item for using synthetics to manufacture.People need Want be have effects that beauty treatment, preserve youthful looks, whitening etc. facilitates more high security skin care item of delay skin aging.
Currently, being usually to add solvent such as water, butanediol, the third two using lavender as the method that raw material extracts skin care ingredient Alcohol, ethyl alcohol etc., by high-temperature boiling, filtering, addition preservative is made.The active material that such method is extracted is mainly macromolecule Compound is unfavorable for skin absorption, and being irritating to the skin property of partial solvent.Therefore, it is high that a kind of more effects of new type natural are sought Safety skin care item have important application value.
Summary of the invention
It is an object of the invention to overcome above-mentioned the shortcomings of the prior art, provide a kind of lavender fermentation magma and its Preparation method and application.The present invention adds saccharomyces cerevisiae by selectively external source and carries out secondary fermentation to lavender, gained at Product have significant skin-protection and health-care effect, and there are also good storage stabilities simultaneously.Microbe fermentation method extract vegetable active at Point, organic solvent is not added, catalysis reaction is carried out to compound contained by whole leaf plant using the enzyme in microbial cell, it is complete to protect Vegetalitas functional component and the fermented small molecule easily absorbed as skin have been stayed, has been reached to the effective of phytochemicals production ingredient It extracts, reaction condition is mild, and reaction process is pure natural, does not need chemical reagent, non-environmental-pollution problem.
In order to achieve the object of the present invention, first technical solution of the present invention is to provide a kind of lavender fermentation magma, former Material is grouped as by the group of following weight ratio: lavender 6-8 parts by weight, pure water 70-85 parts by weight, saccharomyces cerevisiae 7-10 weight Part.
Preferably, the lavender powder particle diameter is 20-30 mesh.
Preferably, the saccharomyces cerevisiae is saccharomyces sake.
A kind of second technical solution of the invention are as follows: preparation method of lavender fermentation magma, comprising the following steps:
S1 chooses dry lavandulae flos, grinding and sieving；
Lavender powder in step S1, pure water, saccharomyces cerevisiae are uniformly mixed by S2, keep temperature 20-30 degree, are stood 48-72 hours；
S3 sterilizing inactivation；
S4 centrifugation is removed slag；
S5 is de-tasted；
S5 adds preservative and retains.
Further, dry lavender described in above-mentioned steps S1 is to be made after french lavender spends drying.
Further, temperature keeps 15-20 degree when crushing operation described in above-mentioned steps S1.
Further, the mesh number of sieving described in above-mentioned steps S1 is 20~30 mesh.
Further, standing described in above-mentioned steps S2 is to seal standing.
Further, time of repose described in above-mentioned steps S2 is 48 hours.
Further, it sterilizes described in above-mentioned steps S3, sterilising temp is 110-130 degree, and sterilization time is 60 minutes.
Further, it is centrifuged described in above-mentioned steps S4, using stacked centrifuge, revolving speed 3000-5000rpm.
Further, it is de-tasted described in above-mentioned steps S5 and boils off taste for negative pressure state backspin.
Further, preservative described in above-mentioned steps S6 is pentanediol 0.5-1.5 parts by weight, hexylene glycol 0.5-1.5 weight Part, parahydroxyacet-ophenone 0.5-1.5 parts by weight.Preferably, 1 parts by weight of pentanediol, 1 parts by weight of hexylene glycol, parahydroxyacet-ophenone 0.5 parts by weight.
Lavender prepared by the present invention fermentation magma completely remains vegetalitas functional component and fermented to become skin easy The small molecule of absorption, particularly useful for making skin care item.
The beneficial effects of the present invention are: the prior art extracts skin care ingredient in lavender using organic solvent or water, cause The shortcomings that extracting incomplete and organic solvent residual stimulation skin, the present invention is original with lavender powder, pure water, saccharomyces cerevisiae Material prepares a kind of lavender fermentation magma by way of microbial fermentation, not only remain the nutrition of lavender itself at Point, it also adds small molecule brought by microbial metabolic products and can absorb nutritional ingredient.Lavender fermentation magma skin care battalion It forms and is divided into natural moisturizing factor, high with skin compatibility and be easy to be absorbed, contained amino, hydroxyl, carboxyl etc. are hydrophilic Moisture can be locked in the cell and have moisture-keeping efficacy by group.
Detailed description of the invention
Fig. 1 is scavenging effect lab diagram of the lavender magma to DPPH free radical
Fig. 2 is the capacity experimental figure of lavender magma scavenging hydroxyl
Fig. 3 is scavenging effect lab diagram of the lavender magma to superoxide anion
Fig. 4 is that lavender magma acts on lab diagram to inhibitory activity against tyrosinase
Specific embodiment
The following describes the present invention in detail with reference to examples.Following embodiment will be helpful to those skilled in the art The present invention is further understood, but the invention is not limited in any way.It should be pointed out that those skilled in the art For, without departing from the inventive concept of the premise, it can also make certain adjustments and improvements.These belong to guarantor of the invention Protect range.
Embodiment 1
Lavender fermentation magma, consisting of: 7 parts by weight of lavender, 83 parts by weight of pure water, 10 weight of saccharomyces sake Part.
It chooses dry method state lavandulae flos to crush, crushing temperature is 15-20 degree, smashes it through 20-30 mesh；By lavender powder 7 parts by weight, 83 parts by weight of pure water, 10 parts by weight of saccharomyces sake are uniformly mixed, and seal standing 48 hours, keep temperature 20-30 degree；It ferments in stopping in 48 hours, heat sterilization, sterilising temp is 110-130 degree, and sterilization time is 60 minutes；Stacked from Scheming centrifugation, revolving speed 3000-5000rpm, waste；Supernatant negative pressure revolving de-tastes, and adds 1 parts by weight of pentanediol, 1 weight of hexylene glycol Part is measured, 0.5 parts by weight of parahydroxyacet-ophenone are retained spare.
Above-mentioned lavender fermentation magma, preparation method, comprising the following steps:
Step 1 chooses dry lavandulae flos, grinding and sieving；
Lavender powder, pure water, saccharomyces cerevisiae are uniformly mixed by step 2, keep temperature 20-30 degree, and it is small to stand 48-72 When；
Step 3, sterilizing inactivation；
Step 4, centrifugation are removed slag；
Step 5 de-tastes；
Step 6, addition preservative are retained.
Efficacy test 1:DPPH radicals scavenging experiment
Experimental method:
(1) it takes the Tris-HCl buffer 4.5mL of 0.05mol/L pH8.2 in test tube, is placed in 25 DEG C of water-baths and preheats 20min；
(2) it is separately added into the sample and 0.4mL of 1mL various concentration, the pyrogallol solution of 2.5mmol/L is (by 10mmol/ L HCl is prepared), 5min is reacted in 25 DEG C of water-baths after mixing；
(3) 8mol/L hydrochloric acid 1.0mL is added and terminates reaction, reference is made with Tris-HCl buffer, blank group is steamed with 0.1mL Distilled water replaces sample test solution, and absorbance is measured at 299nm, calculates clearance rate.Blank control group replaces sample with 1mL sample solvent Three repetitions are done in product, each processing.
Experimental result:
It is experimental group according to the test method of efficacy test 1 using the fermentation magma of lavender made from embodiment 1, passes through DPPH Radicals scavenging experiment can be seen that the increase with lavender magma concentration, and the ability for removing DPPH free radical gradually increases. The ability for showing that lavender magma concentration removes DPPH free radical with it has dose-effect relationship.The lavender magma of 10% concentration can Remove about 98% DPPH free radical.1.17% lavender magma can remove 50% DPPH free radical.
Efficacy test 2:The ability of lavender magma scavenging hydroxyl
Experimental method:
(1) 2mmol/L FeSO is added in 25mL colorimetric cylinder4 3mL、1mmol/L H2O23mL shakes up；Wherein H2O2It is It is eventually adding and starts entire reaction.
(2) it is subsequently added into 6mmol/L salicylic acid 3mL, is shaken up；
(3) it is taken out after 37 DEG C of heating water bath 15min, surveys its absorbance A 0；
(4) certain density prepare liquid 0.2mL, 0.4mL, 0.6mL, 0.8mL, 1.0mL are then respectively adding；
(5) it is then separately added into distilled water 0.8mL, 0.6mL, 0.4mL, 0.2mL, 0mL again, shakes up, continue heating water bath 15min takes out and surveys its absorbance A X.
(6) for after eliminating plus total 1.0mL prepare liquid and distilled water caused by system absorbance value reduction, method is same On, its absorbance value A00 is surveyed after constant temperature 15min, adds 1mL distilled water, surveys primary its absorbance A XX after shaking up again, A reduces= A00-AXX.
Experimental result:
It is experimental group according to the test method of efficacy test 1 using the fermentation magma of lavender made from embodiment 1, passes through removing It is obvious to the scavenging effect of hydroxy radical that the capacity experimental of hydroxy radical can be seen that lavender magma, in 60% concentration range, Increase with lavender magma concentration, the ability of scavenging hydroxyl gradually increases.100% lavender magma can be removed 83.4% hydroxy radical removes the lavender magma of 50% hydroxy radical 19.91% concentration of need.
Efficacy test 3:Scavenging effect of the lavender magma to superoxide anion
Experimental method:
(1) it takes the Tris-HCl buffer of 4.5mL 0.05mol/L pH8.2 in test tube, 4mL deionized water is added, 0.1mL sample mixes, is placed in 25 DEG C of water-baths and preheats 10min；
(2) pyrogallol solution (2.5mmol/L, the 10mmol/L of 25 DEG C of 0.4mL heat preservation 10min are rapidly added after taking out HCl is prepared).
(3) 8mol/L hydrochloric acid 1mL is added and terminates reaction, blank group is compareed with distilled water.
(4) absorbance is measured at 299nm, calculates clearance rate.A1 is sample, A2 control.
Superoxide anion clearance rate (%)=(A1-A2)/A1
Experimental result:
It is experimental group according to the test method of efficacy test 3 using the fermentation magma of lavender made from embodiment 1, by smoking clothing Grassland is starched to the removing of superoxide anion experiment as can be seen that lavender magma is significant to superoxide anion scavenging effect, with smoking Clothing grassland is starched concentration and is increased, and gradually increases to the clearance rate of superoxide anion.After magma concentration is higher than 20%, super oxygen is removed The ability of anion tends towards stability.100% lavender magma 78% or so, removes the Scavenging activity of superoxide anion 50% superoxide anion needs 10.04% lavender magma.
Efficacy test 4:Lavender magma tests the inhibiting rate of l-tyrosine enzyme:
Experimental method:
(1)C1、C2、T1、T2The substance additional amount of pipe is referring to table 3.
(2)C2Pipe prepares shake up after, return to zero under the heating water bath 10min in 37 DEG C of water-baths, wavelength 475nm.
(3)C1Pipe solution, which prepares, to be shaken up, and after 37 DEG C of water-bath 10min, is added tyrosinase 1mL, is continued water-bath 10 minutes, measurement C1Absorbance value.
(4) (1) (2) same method is pressed, with T2Zeroing measurement T1Absorbance value.
(5) sample is calculated to the maximum inhibition T (%) of tyrosinase.Formula: T (%)=(C1-T1)/C1× 100%
1 reagent of table matches table
Experimental result:
It is experimental group according to the test method of efficacy test 3 using the fermentation magma of lavender made from embodiment 1, by smoking clothing The removing experiment to superoxide anion is starched on grassland it can be seen that 1% arbutin is right for the positive of tyrosinase inhibition test According to inhibitory activity against tyrosinase 99.52%.10% lavender magma can inhibit 21.21% tyrosinase activity.Therefore Lavender magma has the function of certain inhibit tyrosinase activity.

Claims (9)

  1. The magma 1. a kind of lavender is fermented, which is characterized in that be grouped as by the group of following weight ratio: lavender powder 6-8 parts by weight, Pure water 70-85 parts by weight, saccharomyces cerevisiae 7-10 parts by weight.
  2. 2. lavender fermentation magma according to claim 1, which is characterized in that the saccharomyces cerevisiae is saccharomyces sake.
  3. 3. according to claim 1 lavender described in any one of -2 fermentation magma preparation method, which is characterized in that including with Lower step:
    S1 chooses dry lavandulae flos, and grinding and sieving obtains lavender powder；
    Lavender powder in step S1, pure water, saccharomyces cerevisiae are uniformly mixed by S2, keep temperature 20-30 degree, stand 48-72 Hour；
    S3 sterilizing inactivation；
    S4 centrifugation is removed slag；
    S5 is de-tasted；
    S6 adds preservative and retains.
  4. 4. the preparation method of lavender fermentation magma according to claim 3, which is characterized in that dry in the step S1 smokes Clothing grass is to be made after french lavender is dry.
  5. 5. the preparation method of lavender fermentation magma according to claim 3, which is characterized in that the crushing in the step S1 Operation temperature keeps 15-20 degree.
  6. 6. the preparation method of lavender fermentation magma according to claim 3, which is characterized in that the standing in the step S2 It is stood to seal.
  7. 7. the preparation method of lavender fermentation magma according to claim 3, which is characterized in that de-tasting in the step S5 Taste is boiled off for negative pressure state backspin.
  8. 8. the preparation method of lavender fermentation magma according to claim 3, which is characterized in that the anti-corrosion in the step S6 Agent group becomes pentanediol 0.5-1.5 parts by weight, hexylene glycol 0.5-1.5 parts by weight, parahydroxyacet-ophenone 0.5-1.5 parts by weight.
  9. 9. application of the fermentation of lavender described in any one of -2 magma in skin care item according to claim 1.
CN201910839895.0A 2019-09-06 2019-09-06 A kind of lavender fermentation magma and its preparation method and application Pending CN110420148A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111297741A (en) * 2019-12-23 2020-06-19 北京工商大学 Preparation and application of pine pollen fermentation extracting solution
CN112870130A (en) * 2021-03-30 2021-06-01 中国科学院合肥物质科学研究院 Preparation method of eucommia pollen fermentation liquor and application of eucommia pollen fermentation liquor in cosmetics

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105147585A (en) * 2015-09-30 2015-12-16 上海全丽生物科技有限公司 Lavender fermented puree and preparation method and application thereof
CN105147586A (en) * 2015-09-30 2015-12-16 上海全丽生物科技有限公司 Rose fermentation puree as well as preparation method and application thereof
CN107440956A (en) * 2017-08-10 2017-12-08 叶夏 A kind of plant fermentation magma facial mask and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105147585A (en) * 2015-09-30 2015-12-16 上海全丽生物科技有限公司 Lavender fermented puree and preparation method and application thereof
CN105147586A (en) * 2015-09-30 2015-12-16 上海全丽生物科技有限公司 Rose fermentation puree as well as preparation method and application thereof
CN107440956A (en) * 2017-08-10 2017-12-08 叶夏 A kind of plant fermentation magma facial mask and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
冯年平等: "《中药经皮给药与功效性化妆品》", 31 May 2019, 中国医药科技出版社 *
陆叶等: "《药用植物学 翻转课堂版》", 31 December 2017, 苏州大学出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111297741A (en) * 2019-12-23 2020-06-19 北京工商大学 Preparation and application of pine pollen fermentation extracting solution
CN111297741B (en) * 2019-12-23 2022-08-26 北京工商大学 Preparation and application of pine pollen fermentation extracting solution
CN112870130A (en) * 2021-03-30 2021-06-01 中国科学院合肥物质科学研究院 Preparation method of eucommia pollen fermentation liquor and application of eucommia pollen fermentation liquor in cosmetics

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