CN110404283A - It is a kind of can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated - Google Patents
It is a kind of can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated Download PDFInfo
- Publication number
- CN110404283A CN110404283A CN201910850616.0A CN201910850616A CN110404283A CN 110404283 A CN110404283 A CN 110404283A CN 201910850616 A CN201910850616 A CN 201910850616A CN 110404283 A CN110404283 A CN 110404283A
- Authority
- CN
- China
- Prior art keywords
- cucurbit
- bottleneck
- rotary evaporators
- concentrated
- quantitative analysis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004445 quantitative analysis Methods 0.000 title claims abstract description 25
- 239000012141 concentrate Substances 0.000 claims abstract description 60
- 238000010079 rubber tapping Methods 0.000 claims description 40
- 238000000429 assembly Methods 0.000 claims description 26
- 230000000712 assembly Effects 0.000 claims description 26
- 230000005540 biological transmission Effects 0.000 claims description 26
- 238000010438 heat treatment Methods 0.000 claims description 22
- 239000000523 sample Substances 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 8
- 239000011521 glass Substances 0.000 claims description 7
- 239000004810 polytetrafluoroethylene Substances 0.000 claims description 6
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims description 6
- 239000003365 glass fiber Substances 0.000 claims description 5
- -1 polytetrafluoroethylene Polymers 0.000 claims description 3
- 238000010025 steaming Methods 0.000 claims description 3
- 238000009833 condensation Methods 0.000 claims description 2
- 230000005494 condensation Effects 0.000 claims description 2
- 238000000465 moulding Methods 0.000 claims description 2
- 210000005239 tubule Anatomy 0.000 abstract description 11
- 238000013461 design Methods 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 2
- 239000012530 fluid Substances 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 description 15
- 230000008020 evaporation Effects 0.000 description 12
- 239000007788 liquid Substances 0.000 description 8
- 238000004821 distillation Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 238000002390 rotary evaporation Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000007701 flash-distillation Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000005292 vacuum distillation Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/08—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping in rotating vessels; Atomisation on rotating discs
- B01D3/085—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping in rotating vessels; Atomisation on rotating discs using a rotary evaporator
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/10—Vacuum distillation
- B01D3/106—Vacuum distillation with the use of a pump for creating vacuum and for removing the distillate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
- B01D3/42—Regulation; Control
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
Abstract
The present invention relates to equipment of chemical industry technical fields, particularly, are related to a kind of Rotary Evaporators, and in particular to it is a kind of can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated.It is of the present invention can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, one cucurbit of former Rotary Evaporators is changed to the cucurbit group of at least two cucurbits, raw water (oil) bath is changed to heat tape, each cucurbit in cucurbit group is sequentially connected and is rotated along same axis, the angle that has a down dip of rotation axis and horizontal plane be 2~44 between a certain degree, divide into bracket support between each cucurbit.Leakage fluid dram is formed at the minimum level of each cucurbit operating position and connects cup scale metered tubule, cup scale metered tubule respectively sets a valve up and down, it stops rotating immediately when the amount of concentrate reaches the correct amount of design, the cooperation opening and closing of two valves can realize the accurate quantitative analysis discharge of concentrate in each cucurbit under the premise of without dismantling cucurbit, not producing bigger effect to negative pressure in system.
Description
Technical field
The present invention relates to equipment of chemical industry technical fields, particularly, are related to a kind of Rotary Evaporators, and in particular to a kind of
Can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated.
Background technique
Rotary Evaporators are a kind of extraction experimental facilities that vacuum distillation concentration is carried out to material, are widely used in sample
Scale concentration, in the dry, experiment such as extract recycling, particularly for a large amount of solvents of flash distillation.Existing Rotary Evaporators are usual
It is made of components such as vacuum evacuation device, heating device, condensing unit, rotating devices, the principle of Rotary Evaporators mainly passes through
Electronic equipment control, makes flask in the case where being most suitable for revolving speed, and constant speed rotary makes solvent form film, increases disengagement area, and pass through
Vacuum pump makes evaporation flask be in negative pressure state, and evaporation flask is placed in constant temperature in water-bath or oil bath pan while rotating and adds
Heat, heating temperature are close to the boiling point of the solvent, so that solution carries out heating diffusion under negative pressure and evaporates in bottle, realize solvent
Rapid evaporation.
Existing Rotary Evaporators can only once distill a sample for one in use, and working efficiency is low.It is existing
Parallel evaporator can once be concentrated by evaporation multiple samples, but it is by shaking the multiple test tubes being placed in parallel vertically under negative pressure
What shape evaporation tube was completed to be concentrated by evaporation, since the disengagement area of each sample is small far beyond Rotary Evaporators, working efficiency is not yet
It is high.In addition, under the premise of not produced bigger effect to negative pressure in system, for being concentrated in cucurbit in distillation process or evaporation tube
Stopping distillation when the amount of liquid is how many can just make concentrate accurately can not determine and control up to the correct amount of setting.
Summary of the invention
The present invention provides it is a kind of can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, solve a rotation
Evaporimeter can only once distill the inefficiency problem of a sample, also solve the premise not produced bigger effect to negative pressure in system
The problem of lower concentrate accurate quantitative analysis controls.
To achieve the above object, the present invention provides it is a kind of can an accurate quantitative analysis rotary evaporations of multiple samples is concentrated
Instrument, comprising: bracket is fixed with rotating electric machine on the bracket；
By the rotation of transmission body drive cucurbit group, (Rotary Evaporators of the present invention are additionally provided with described in control the rotating electric machine
The control panel of rotating electric machine revolving speed and heating temperature, is not shown in the figure), described transmission body one end is fixed with dismountable distillation
Bottle group, the other end are fixed with dismountable condenser；
The condenser bottom is connected with receiving flask；
The cucurbit group includes at least two cucurbit；
Preferably, the cucurbit group includes 2~6 cucurbits；
Each cucurbit of the cucurbit group is sequentially connected and is rotated along same axis；
The rotation axis and horizontal plane have a down dip angle, the angle that has a down dip be 2~44 between a certain degree；
Preferably, a certain degree between the angle that has a down dip is 5~40；
It is further preferred that the angle that has a down dip be 10~35 between a certain degree；
Foundation is successively the first cucurbit, after-fractionating from the near to the distant at a distance from the transmission body in the cucurbit group
Bottle etc., that cucurbit farthest apart from the transmission body set 2 bottlenecks, are the first bottleneck and third bottleneck respectively, remaining is
It is the first bottleneck, the second bottleneck and third bottleneck respectively if 3 bottlenecks；
Recently, the second bottleneck is farthest, institute for the first bottleneck of each cucurbit and transmission body distance in the cucurbit group
State the line of centres and rotation axis coincident of the second bottleneck of each cucurbit and the first bottleneck of each cucurbit, each steaming
At the minimum level for the bottom sidewall that the third bottleneck for evaporating bottle is each provided at its operating position, it is mainly used for arranging concentrate, it is also possible to
It is connected with concentrate dosing assemblies in the third bottleneck of charging, the cucurbit, realizes the accurate quantitative analysis control of concentrate；
First bottleneck of first cucurbit and the transmission body airtight connection, the second bottleneck of first cucurbit
With the first bottleneck ground airtight connection where the first bottleneck of after-fractionating bottle and use clamp；
The after-fractionating bottle sets 3 bottlenecks, is the first bottleneck of after-fractionating bottle, second bottle of after-fractionating bottle respectively
Second bottleneck of the third bottleneck of mouth and after-fractionating bottle, the first bottleneck of the after-fractionating bottle and first cucurbit is ground
Mouthful airtight connection simultaneously uses clamp, the second bottleneck of the after-fractionating bottle and the where the first bottleneck of third cucurbit
One bottleneck ground airtight connection simultaneously uses clamp；
First bottleneck of the cucurbit farthest apart from the transmission body and the second bottleneck ground of secondary remote cucurbit are closed
It connects and uses clamp；
From the after-fractionating bottle to the cucurbit farthest apart from the transmission body in the cucurbit group, their first
The position of bottleneck is between from the first bottle mouth position of first cucurbit to the transmission body and the condenser interface
A certain position；
Preferably, from the after-fractionating bottle to the cucurbit farthest apart from the transmission body, their the first bottleneck
Position is the interface of the transmission body and the condenser；
Bracket is divided between each cucurbit to be used to support, and sets first between first cucurbit, after-fractionating bottle
Bracket sets the second bracket between the after-fractionating bottle, third cucurbit；
Preferably, the first bottleneck where the first bottleneck of each cucurbit is equipped with spherical structure, is used for anti-bumping；
The concentrate dosing assemblies are the quantity tube with quantitative graduation mark, and separate by being set to the quantity tube
The drain of the second tapping valve control concentrate of cucurbit third bottleneck one end and system sealing；
The third bottle mouth position of the cucurbit be provided with the first tapping valve carry out concentrate emission control and cucurbit it is close
Envelope；
First tapping valve and the second tapping valve can be glass material or polytetrafluoroethylene (PTFE) material；
The third bottleneck of the concentrate dosing assemblies and the cucurbit is an integral molding structure or ground airtight connection
And it is fixed with fixture；
The concentrate dosing assemblies are additionally provided with quantitative volume increasing device far from third bottleneck one end of the cucurbit, for real
The disposable increase-volume tapping of existing concentrate；
The quantitative volume increasing device includes the multiple of different capabilities, to carry out selection replacement according to the capacity requirement of concentrate；
The concentrate dosing assemblies and the quantitative volume increasing device glass ground joint airtight connection；
The quantitative volume increasing device neck is equipped with annular and connects disk for containing the solution of quantity tube outflow；
Each cucurbit in the cucurbit group passes through heating component and is heated, and the heating component is is set to
The heat tape at the outer wall of cucurbit is stated, and the preferably heat tape swathes at the outer wall of the cucurbit；
The outer layer of the heat tape is provided with glass fiber tape, realizes the heat-insulated of the heat tape and fixes；
Temperature controller sensor probe is additionally provided between the heat tape and the cucurbit.
It is of the present invention can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, original 1 cucurbit is changed
Into for the cucurbit group including at least two cucurbit, the former cucurbit for there was only 1 bottleneck 3 bottlenecks have been improved to (from transmission
A farthest cucurbit of body is equipped with 2 bottlenecks), each cucurbit the sequentially closed series connection of ground and is fixed two-by-two with fixture, even
The place of connecing, which divides into bracket support, ensures that each cucurbit is rotated along same axis, and the minimum level position of each cucurbit working condition sets
Three bottlenecks, the third bottleneck connect with concentrate dosing assemblies, and the concentrate dosing assemblies are provided with quantitative tubule, described fixed
There is graduation mark on amount tubule, the quantitative tubule sets the first tapping valve close to one end of cucurbit, and the quantitative tubule is far from steaming
The one end for evaporating bottle sets the second tapping valve, and rotary evaporation starts, and closes the second tapping valve (as needed using when quantitative volume increasing device the
Two tapping valves open), open the first tapping valve can intuitively observe concentration liquid measure slight change, when concentrate close to design
When correct amount, revolving speed is slowed down, is stopped rotating immediately when concentrate reaches the correct amount of design, closes first drain rapidly
Valve is opened second tapping valve and (is closed as needed using the second tapping valve when quantitative volume increasing device, after removing quantitative volume increasing device
The second tapping valve is opened again), the concentrate that the cooperation of two valves can release accurate quantitative analysis can for measuring the indexs such as reaction yield
The unification for realizing examination criteria, performance indicator and the same sample that can also study the different concentrates of more identical yield are different
The concentrate performance indicator of concentrating degree.Meanwhile Rotary Evaporators of the present invention, with heat tape replace existing water-bath or
Oil bath pan heats the cucurbit, advantage as heating component: (1) eliminating steric hindrance, be easily installed concentrate
Dosing assemblies and increased cucurbit, (2) make the volume-diminished of Rotary Evaporators, and reduce the heating in evaporation process
With water consume and oil consumption；(3) since the direct tapping of concentrate may be implemented in the cucurbit, so that entire Rotary Evaporators are not necessarily to
Using jacking system, reduces the component of entire Rotary Evaporators, saved cost.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of Rotary Evaporators described in the embodiment of the present invention；
Fig. 2 is another cucurbit attachment structure schematic diagram of Rotary Evaporators described in the embodiment of the present invention；
Fig. 3 is that another structural schematic diagram of Rotary Evaporators described in the embodiment of the present invention and another distillation bottle structure show
It is intended to；
Fig. 4 is the third cucurbit structural schematic diagram of Rotary Evaporators described in the embodiment of the present invention；
In the figure, it is marked as 1- bracket, 2- rotating electric machine, 3- transmission body, 4- cucurbit group (including 41,42,43), 5- condensation
Device, 6- receiving flask, 7- concentrate dosing assemblies (including 71,72,73,74), 8- fixture, 9- quantify volume increasing device, 10- electric heating
Band, 11- glass fiber tape, 12- temperature sensor, 13- bracket (including 131,132), 14- annular connects disk；
The first cucurbit of 41-, 42- after-fractionating bottle, 43- third cucurbit, 71- quantify graduation mark, 72- quantity tube, 73-
First bleeder valve, the second bleeder valve of 74-, the first bracket of 131-, the second bracket of 132-；
First bottleneck of the first cucurbit of 411-, the second bottleneck of the first cucurbit of 412-, the first cucurbit of 413-
The third of three bottlenecks, the first bottleneck of 421- after-fractionating bottle, the second bottleneck of 422- after-fractionating bottle, 423- after-fractionating bottle
Bottleneck, the first bottleneck of 431- third cucurbit, 433- third cucurbit third bottleneck；
First bottleneck of 411 '-the first cucurbits, the first bottleneck of 421 '-after-fractionating bottles, 431 '-third cucurbits
First bottleneck.
Specific embodiment
In order to make the foregoing objectives, features and advantages of the present invention clearer and more comprehensible, with reference to the accompanying drawing and specific real
Applying mode, the present invention is described in further detail.
Rotary Evaporators of the present invention are the RE-3000A type Rotary Evaporators produced with factory, Shanghai Yarong Biochemical Instrument Plant
Based on be transformed.
Embodiment 1
Referring to shown in Fig. 1, described in the present embodiment can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, comprising:
Bracket 1, rotating electric machine 2 is fixed on the bracket 1, and (Rotary Evaporators of the present invention can also be equipped with and control the rotating electric machine parameter
The control panel of revolving speed and heating temperature, is not shown in the figure), and control revolving speed, control assembly of heating temperature etc..The rotation
Rotating motor 2 drives cucurbit group 4 to rotate by transmission body 3, and described 3 one end of transmission body is fixed with dismountable cucurbit group 4, separately
One end is fixed with dismountable condenser 5, and the condenser bottom is connected with receiving flask 6, for collecting fraction, the condenser
5 tops are connected with vacuum pump (not shown)；
The cucurbit group 4 includes 3 cucurbits: the first cucurbit 41, after-fractionating bottle 42 and third cucurbit 43, point
Not Sheng Zhuan solution to be concentrated 1,3,3 solution to be concentrated 2, solution to be concentrated solutions to be concentrated can come from same sample, also may be from difference
Sample.First cucurbit 41, the after-fractionating bottle 42, the third cucurbit 43 are sequentially connected in series fixation, each to distill
Bracket 13 is set between bottle, sets the first bracket 131 between first cucurbit 41, after-fractionating bottle 42, the after-fractionating bottle 42,
The second bracket 132 is set between third cucurbit 43, bracket 13 is used to support cucurbit group 4, it is ensured that first cucurbit 41,
Two cucurbits 42 and third cucurbit 43 are rotated along same axis, and the rotation axis and horizontal plane have a down dip angle, under described
The angle that inclines be 2~44 between a certain degree, such as select 15 °.
First cucurbit 41 sets 3 bottlenecks, is the first bottleneck 411, the first cucurbit of the first cucurbit respectively
The third bottleneck 413 of second bottleneck 412 and the first cucurbit, the first bottleneck 411 of first cucurbit and the transmission body
Airtight connection (is connected as the prior art), and the second bottleneck 412 of first cucurbit and 42 ground of after-fractionating bottle are close
It closes connection and is fastened with fixture 8, the third bottleneck 413 of first cucurbit is connected with concentrate dosing assemblies 7；
The after-fractionating bottle sets 3 bottlenecks, be respectively the first bottleneck 421 of after-fractionating bottle, after-fractionating bottle
The third bottleneck 423 of two bottlenecks 422 and after-fractionating bottle, the first bottleneck where the first bottleneck 421 of the after-fractionating bottle
421 ' with the 412 ground airtight connection of the second bottleneck of first cucurbit and with the fastening of fixture 8, and the of the after-fractionating bottle
Two bottlenecks 422 and the 431 ' ground airtight connection of the first bottleneck where the first bottleneck 431 of the third cucurbit and with fixture 8
Fastening, the third bottleneck 423 of the after-fractionating bottle are connected with concentrate dosing assemblies 7；
The third cucurbit sets 2 bottlenecks, be respectively third cucurbit the first bottleneck 431 and third cucurbit
Three bottlenecks 433, the first bottleneck 431 ' and the second of the after-fractionating bottle where the first bottleneck 431 of the third cucurbit
422 ground airtight connection of bottleneck is simultaneously fastened with fixture 8, the third bottleneck 433 and concentrate dosing assemblies 7 of the third cucurbit
It is connected.
Rotary Evaporators of the present invention at work, steam by the first bottleneck 421 ' of the after-fractionating bottle, the third
The length for evaporating the first bottleneck 431 ' of bottle reaches the transmission body 3 and 5 interface of condenser.
As shown in Fig. 2, the first bottleneck 421 ' of the first bottleneck 411 ' of first cucurbit, the after-fractionating bottle and
First bottleneck 431 ' of the third cucurbit is being equipped with spherical structure at respective cucurbit；Spherical structure is not only prevented
Only solution to be concentrated bumping, and fixed convenient for the ground airtight connection between cucurbit.
The third bottleneck of first cucurbit 41, after-fractionating bottle 42 and third cucurbit 43 is each provided at respective working position
At the minimum level set, it is mainly used for arranging concentrate, the direction of adjustment third bottleneck can be used for feeding；The cucurbit
Third bottleneck is connected with concentrate dosing assemblies 7, realizes the accurate quantitative analysis control of concentrate.
The concentrate dosing assemblies 7 can be integrally formed structures with each cucurbit third bottleneck or be logical
The structure that grournd glass carries out airtight connection is crossed, and fixed with fixture 8, this example selects the latter.
The concentrate dosing assemblies 7 are the quantity tube 72 with quantitative graduation mark 71, and described quantitative by being set to
The drain and Distallation systm sealing of second tapping valve 74 control concentrate of the pipe 72 far from described cucurbit one end.
The third bottle mouth position of each cucurbit is provided with the emission control and distillation that the first tapping valve 73 carries out concentrate
Bottle sealing.
First tapping valve 73 and the second tapping valve 74 can be glass material or polytetrafluoroethylene (PTFE) material.
The position of third bottleneck of the concentrate dosing assemblies far from the cucurbit is equipped with quantitative increase also according to needs
Container 9, for realizing the disposable increase-volume tapping of concentrate.
The quantitative volume increasing device 9 includes the multiple of different capabilities, carries out selection replacement according to the capacity requirement of concentrate.
The concentrate dosing assemblies 7 (are schemed with the quantitative 9 glass ground joint airtight connection of volume increasing device and with fixture 8 is fixed
In be not shown).
Quantitative 9 neck of volume increasing device is equipped with annular and connects disk 14 for containing the solution of quantity tube outflow.The cucurbit
Each cucurbit in group passes through heating component and is heated, and the heating component is to be set at the outer wall of the cucurbit
Heat tape 10, and the preferably heat tape swathes at the outer wall of the cucurbit.
The outer layer of the heat tape is provided with glass fiber tape 11, realizes the heat-insulated of the heat tape and fixes.
Temperature controller sensor probe 12 is additionally provided between the heat tape and the cucurbit.
It is of the present invention can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, original 1 cucurbit is changed
Into the cucurbit group 4 for 3 cucurbits, cucurbit two-by-two sequentially ground it is closed series connection and with fixture 8 fixation, junction sets bracket
13 supports, can 3 solutions to be concentrated of a rotary evaporation, existing parallel evaporator can once be concentrated by evaporation the excellent of multiple samples
Point, and have big efficient of Rotary Evaporators disengagement area.The cucurbit of only one former bottleneck 3 bottleneck (thirds have been changed to
A cucurbit has 2 bottlenecks), each mouth is used equally for feeding, and the minimum level position of each cucurbit working condition sets third bottle
Mouthful, the third bottleneck of each cucurbit is all provided with the first tapping valve 73 and connect with concentrate dosing assemblies 7, the concentrate
Dosing assemblies 7 are provided with quantitative tubule 72, there is graduation mark 71 on the quantitative tubule, the quantitative tubule far from cucurbit one
End sets the second tapping valve 74.Rotary Evaporators described in the present embodiment close the 74 (root of the second tapping valve when distilling beginning
Opened according to the second tapping valve 74 when needing to use quantitative volume increasing device 9), it opens first tapping valve 73 and makes in the cucurbit
The negative pressure state inside Distallation systm is still kept, can intuitively observe concentration by the scale on quantitative tubule 72 in distillation process
The variation of liquid measure slows down revolving speed when correct amount of the liquid measure close to design is concentrated, when concentration liquid measure reaches the correct amount of design
It stops rotating immediately, and closes first tapping valve 73 rapidly, and open second tapping valve 74 and (use determine as needed
Second tapping valve 74 is closed when measuring volume increasing device 9, opens the second tapping valve again after removing quantitative volume increasing device 9), the dense of amount is determined at this time
Contracting liquid is released, and for calculating yield index, is also used to study the performance difference of the concentrate of different samples.
Rotary Evaporators of the present invention replace existing water-bath or oil bath pan as heating component using heat tape, right
The cucurbit is heated, advantage: (1) eliminating steric hindrance, be easily installed concentrate dosing assemblies 7 and after-fractionating bottle
42, third cucurbit 43；(2) volume-diminished of Rotary Evaporators also reduces water for heating consumption and oil in evaporation process
Consumption；(3) since the direct tapping of concentrate may be implemented in the cucurbit, so that Rotary Evaporators are without using jacking system,
The component for reducing Rotary Evaporators, has saved cost.
Rotary Evaporators as shown in Figure 1, concentrate dosing assemblies described in the present embodiment are preferably quantity tube 72, described fixed
With quantitative graduation mark 71 at the outer wall of buret, the magnitude for concentrate is read, and as the structure that can choose, this implementation
The example quantity tube 72 can be the measurable tubule of thin cylinder structure for cavity, and measurable capacity is advisable with 1-10mL,
Metering scale can be as accurate as 0.01mL or even 0.005mL.
As the structure that can be converted, the Rotary Evaporators as shown in Figure 1, in the quantity tube 72 close to described
Quantitative volume increasing device 9 is additionally provided at second tapping valve 74, when the capacity of the quantity tube 72, which is unable to satisfy concentrate capacity, to be needed,
Can be increased by way of adding the quantitative volume increasing device 9 concentrate can quantitative volumetric, and realize that aequum is dense with this
The disposable tapping of contracting liquid reduces the error for needing repeatedly to read due to multiple tapping, helps to improve the accurate meter of concentrate
Amount.The quantitative volume increasing device and the quantity tube are cooperated by accurately metering, realize the dilatation to quantity tube 72.The present embodiment
The quantitative volume increasing device 9 includes the multiple of different capabilities, to carry out selection replacement according to the design capacity of concentrate, as will be described
The Capacity design of quantitative volume increasing device 9 be 1mL, 2mL, 3mL, 5mL, 10mL, 20mL etc. it is multiple be one group, according to required concentrate
Capacity Selection suitably quantifies the disposable accurate tapping that volume increasing device 9 carries out concentrate.The shape of the quantitative volume increasing device 9 can be with
Suitable bend pipe connecting tube, flat bottle structure or spherical shape are selected for the distance according to the cucurbit apart from operating platform.
In Rotary Evaporators structure as shown in Figure 1, the heating component is used for the solution to be concentrated in the cucurbit
Heating evaporation processing is carried out, in the present embodiment, the heating component is the heat tape swathed at the outer wall of the cucurbit,
The heat tape 10 passes through the heat transfer of cucurbit bottle wall, carries out heating evaporation to solution to be concentrated therein, and preferably by institute
It states heat tape annularly to swathe at the outer wall of the cucurbit, to guarantee the uniform of heating.Meanwhile outside the heat tape
It is provided with glass fiber tape 11, as heat-barrier material and fixing layer to realize the heat-insulated of the heat tape and fixation, and it is described
It is additionally provided with temperature controller sensor probe 12 between heat tape 10 and the outer wall of the cucurbit, carries out the spy of heating temperature
It surveys.
It is contained respectively to be concentrated as the structure that can be converted as shown in figure 3, the cucurbit group includes 6 cucurbits
1~6,6 solutions to be concentrated of liquid can come from same sample, also may be from different samples.The connection type of 6 cucurbits and add
Hot mode is identical as 3 cucurbits.
As the structure that can be converted, the cucurbit number that the cucurbit group includes can be 2,4,5.
As the structure that can be converted, each cucurbit of the cucurbit group can be shape as shown in Figure 3, can also be with
It is shape as shown in Figure 4.Cucurbit bottle body rotation axis top and the bottom shown in Fig. 4 quality is close or suitable.
The embodiment of the present invention has been described in detail above, specific case used herein to the principle of the present invention and
Embodiment is expounded, and the above description of the embodiment is only used to help understand the method for the present invention and its core ideas；
At the same time, for those skilled in the art can in specific embodiments and applications according to the thought of the present invention
There is change place, in conclusion the contents of this specification are not to be construed as limiting the invention.
Claims (10)
1. one kind can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated characterized by comprising bracket (1), it is described
Rotating electric machine (2) are fixed on bracket 1；The rotating electric machine (2) drives cucurbit group (4) rotation by transmission body (3), described
Transmission body (3) one end is fixed with dismountable cucurbit group (4), and the other end is fixed with dismountable condenser (5), the condensation
Device (5) bottom is connected with receiving flask (6)；
The cucurbit group (4) includes at least two cucurbit；
Each cucurbit of the cucurbit group (4) is sequentially connected and is rotated along same axis；
The rotation axis and horizontal plane have a down dip angle, the angle that has a down dip be 2~44 between a certain degree；
According to being successively the first cucurbit (41), the from the near to the distant at a distance from the transmission body (3) in the cucurbit group (4)
Two cucurbits (42) etc., that cucurbit farthest apart from the transmission body (3) set 2 bottlenecks, are the first bottleneck and the respectively
Three bottlenecks, remaining each cucurbit are all provided with 3 bottlenecks, are the first bottleneck, the second bottleneck and third bottleneck respectively；
Recently, the second bottleneck is farthest for the first bottleneck of each cucurbit and the transmission body (3) distance in the cucurbit group (4),
Second bottleneck of each cucurbit and the line of centres and rotation axis coincident of the first bottleneck, the third bottle of each cucurbit
Mouth takes shape at the minimum level of cucurbit operating position and is connected with concentrate dosing assemblies (7)；
The first bottleneck (411) of first cucurbit and the transmission body airtight connection, second bottle of first cucurbit
First bottleneck (421 ') ground airtight connection where the first bottleneck (421) of mouthful (412) and the after-fractionating bottle and with pressing from both sides
Has (8) fastening；
First bottle where the second bottleneck (422) of the after-fractionating bottle and the first bottleneck (431) of the third cucurbit
Neck (431 ') ground airtight connection is simultaneously fastened with fixture (8)；
Second of bottleneck and described remote cucurbit where first bottleneck of the cucurbit farthest apart from the transmission body (3)
Bottleneck ground airtight connection is simultaneously fastened with fixture (8)；
Bracket (13) is divided between each cucurbit to be used to support；
From the after-fractionating bottle to the cucurbit farthest apart from the transmission body (3) in the cucurbit group (4), they
The position of first bottleneck is to connect from the first bottle mouth position of first cucurbit to the transmission body (3) and the condenser (5)
A certain position between mouthful；
Each cucurbit in the cucurbit group passes through heating component and is heated, and the heating component is to be set to the steaming
Evaporate the heat tape (10) at the outer wall of bottle.
2. one kind according to claim 1 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In the first bottleneck where the first bottleneck of each cucurbit is equipped with spherical structure.
3. one kind according to claim 1 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In the outer layer of the heat tape (10) is provided with glass fiber tape (11), realizes the heat-insulated of the heat tape (10) and consolidates
It is fixed, temperature controller sensor probe (12) are additionally provided between the heat tape (10) and the cucurbit.
4. one kind according to claim 1 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In the concentrate dosing assemblies (7) are the quantity tube (72) with quantitative graduation mark (71), and remote in the quantity tube (72)
One end from cucurbit is equipped with the second tapping valve (74)；
Each cucurbit third bottle mouth position is provided with the first tapping valve (73)；
The emission control of first tapping valve (73) and the second tapping valve (74) cooperation opening and closing progress concentrate and cucurbit are close
Envelope.
5. one kind according to claim 4 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In first tapping valve (73) and the second tapping valve (74) can be glass material or polytetrafluoroethylene (PTFE) material.
6. one kind according to claim 1 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
Be an integral molding structure in, concentrate dosing assemblies (7) and the cucurbit third bottleneck or for ground airtight connection simultaneously
It is fixed by fixture (8).
7. one kind according to claim 1 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In the concentrate dosing assemblies (7) are additionally provided with quantitative volume increasing device (9) far from the end of the cucurbit third bottleneck, are used for
Realize the disposable increase-volume tapping of concentrate.
8. one kind according to claim 7 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In quantitative volume increasing device (9) include the multiple of different capabilities, carry out selection replacement according to the capacity requirement of concentrate.
9. one kind according to claim 7 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In the concentrate dosing assemblies (7) are with quantitative volume increasing device (9) the glass ground joint airtight connection and fixed with fixture (8).
10. one kind according to claim 7 can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated, feature exists
In described quantitative volume increasing device (9) neck can be equipped with annular and connect disk (14).
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910850616.0A CN110404283B (en) | 2019-09-10 | 2019-09-10 | Rotary evaporator capable of accurately and quantitatively concentrating multiple samples at one time |
| PCT/CN2020/114217 WO2021047537A1 (en) | 2019-09-10 | 2020-09-09 | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time |
| EP20863417.0A EP4008418B1 (en) | 2020-09-09 | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time | |
| US17/687,897 US20220184521A1 (en) | 2019-09-10 | 2022-03-07 | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910850616.0A CN110404283B (en) | 2019-09-10 | 2019-09-10 | Rotary evaporator capable of accurately and quantitatively concentrating multiple samples at one time |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110404283A true CN110404283A (en) | 2019-11-05 |
| CN110404283B CN110404283B (en) | 2024-03-22 |
Family
ID=68370507
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910850616.0A Active CN110404283B (en) | 2019-09-10 | 2019-09-10 | Rotary evaporator capable of accurately and quantitatively concentrating multiple samples at one time |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110404283B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110404282A (en) * | 2019-09-10 | 2019-11-05 | 北京师范大学 | It is a kind of can an accurate quantitative analysis recycle the Rotary Evaporators of multiple solvents |
| CN110478928A (en) * | 2019-09-25 | 2019-11-22 | 北京师范大学 | It is a kind of once can accurate quantitative analysis more rotary shaft evaporimeters of multiple samples are concentrated |
| WO2021047537A1 (en) * | 2019-09-10 | 2021-03-18 | 北京师范大学 | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time |
Citations (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB341882A (en) * | 1929-09-17 | 1931-01-19 | Commw Hotel | Method of and apparatus for treating hydrocarbons |
| US3417000A (en) * | 1965-10-23 | 1968-12-17 | Peter G. Chaconas | Multi-stage still |
| US5639354A (en) * | 1994-11-17 | 1997-06-17 | Resona Innovation Ag | Distillation device |
| FR2860987A1 (en) * | 2003-10-15 | 2005-04-22 | Cheng Ming Chou | Multistage process for distillation, cooling and freezing under vacuum to separate solutions and desalinate seawater at constant temperature |
| US20110073459A1 (en) * | 2009-09-25 | 2011-03-31 | Adjabeng George M | Rotary evaporator |
| CN104801056A (en) * | 2015-04-26 | 2015-07-29 | 朱金凤 | Intelligent temperature-control evaporation device |
| CN204563629U (en) * | 2015-02-15 | 2015-08-19 | 福州外语外贸学院 | A kind of Rotary Evaporators |
| CN205007600U (en) * | 2015-09-18 | 2016-02-03 | 重庆工业职业技术学院 | A rotary evaporato that is used for sweet -scented osmanthus seed petrol to extract |
| US20170209805A1 (en) * | 2014-07-22 | 2017-07-27 | Hans Heidolph GmbH | Rotary evaporator having a fastening device with clamping elements |
| CN206381654U (en) * | 2016-12-22 | 2017-08-08 | 南京谷睿生物科技有限公司 | A kind of rotary evaporator |
| CN206688261U (en) * | 2017-04-21 | 2017-12-01 | 钦州学院 | A kind of double spherical anti-splash balls |
| CN107970630A (en) * | 2018-01-02 | 2018-05-01 | 北京师范大学 | Rotary evaporating device with heat tape |
| CN108043058A (en) * | 2018-01-23 | 2018-05-18 | 北京师范大学 | It is a kind of accurately to realize the quantitative Rotary Evaporators of fraction |
| CN108043059A (en) * | 2018-01-23 | 2018-05-18 | 北京师范大学 | It is a kind of accurately to realize the quantitative Rotary Evaporators of concentrate |
| US20180361270A1 (en) * | 2015-07-03 | 2018-12-20 | Basf Se | Distillation device comprising a column which has three or a plurality of cells in series through which fluid flows and method for distilling or extractive distillation by use of the distillation device |
| CN208482027U (en) * | 2018-01-24 | 2019-02-12 | 南通市食品药品监督检验中心 | A kind of novel integrated distillation apparatus |
| CN208493280U (en) * | 2018-06-12 | 2019-02-15 | 西南石油大学 | Rotary evaporator and rotary evaporation system |
| CN109395426A (en) * | 2018-12-18 | 2019-03-01 | 山东天元盈康检测评价技术有限公司 | A kind of Rotary Evaporators suitable for chemical detection |
| CN210845327U (en) * | 2019-09-10 | 2020-06-26 | 北京师范大学 | Rotary evaporator capable of accurately and quantitatively concentrating multiple samples at one time |
| CN211215487U (en) * | 2019-09-10 | 2020-08-11 | 北京师范大学 | Rotary evaporator capable of accurately and quantitatively recovering multiple solvents at one time |
-
2019
- 2019-09-10 CN CN201910850616.0A patent/CN110404283B/en active Active
Patent Citations (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB341882A (en) * | 1929-09-17 | 1931-01-19 | Commw Hotel | Method of and apparatus for treating hydrocarbons |
| US3417000A (en) * | 1965-10-23 | 1968-12-17 | Peter G. Chaconas | Multi-stage still |
| US5639354A (en) * | 1994-11-17 | 1997-06-17 | Resona Innovation Ag | Distillation device |
| FR2860987A1 (en) * | 2003-10-15 | 2005-04-22 | Cheng Ming Chou | Multistage process for distillation, cooling and freezing under vacuum to separate solutions and desalinate seawater at constant temperature |
| US20110073459A1 (en) * | 2009-09-25 | 2011-03-31 | Adjabeng George M | Rotary evaporator |
| US20170209805A1 (en) * | 2014-07-22 | 2017-07-27 | Hans Heidolph GmbH | Rotary evaporator having a fastening device with clamping elements |
| CN204563629U (en) * | 2015-02-15 | 2015-08-19 | 福州外语外贸学院 | A kind of Rotary Evaporators |
| CN104801056A (en) * | 2015-04-26 | 2015-07-29 | 朱金凤 | Intelligent temperature-control evaporation device |
| US20180361270A1 (en) * | 2015-07-03 | 2018-12-20 | Basf Se | Distillation device comprising a column which has three or a plurality of cells in series through which fluid flows and method for distilling or extractive distillation by use of the distillation device |
| CN205007600U (en) * | 2015-09-18 | 2016-02-03 | 重庆工业职业技术学院 | A rotary evaporato that is used for sweet -scented osmanthus seed petrol to extract |
| CN206381654U (en) * | 2016-12-22 | 2017-08-08 | 南京谷睿生物科技有限公司 | A kind of rotary evaporator |
| CN206688261U (en) * | 2017-04-21 | 2017-12-01 | 钦州学院 | A kind of double spherical anti-splash balls |
| CN107970630A (en) * | 2018-01-02 | 2018-05-01 | 北京师范大学 | Rotary evaporating device with heat tape |
| CN108043058A (en) * | 2018-01-23 | 2018-05-18 | 北京师范大学 | It is a kind of accurately to realize the quantitative Rotary Evaporators of fraction |
| CN108043059A (en) * | 2018-01-23 | 2018-05-18 | 北京师范大学 | It is a kind of accurately to realize the quantitative Rotary Evaporators of concentrate |
| CN208482027U (en) * | 2018-01-24 | 2019-02-12 | 南通市食品药品监督检验中心 | A kind of novel integrated distillation apparatus |
| CN208493280U (en) * | 2018-06-12 | 2019-02-15 | 西南石油大学 | Rotary evaporator and rotary evaporation system |
| CN109395426A (en) * | 2018-12-18 | 2019-03-01 | 山东天元盈康检测评价技术有限公司 | A kind of Rotary Evaporators suitable for chemical detection |
| CN210845327U (en) * | 2019-09-10 | 2020-06-26 | 北京师范大学 | Rotary evaporator capable of accurately and quantitatively concentrating multiple samples at one time |
| CN211215487U (en) * | 2019-09-10 | 2020-08-11 | 北京师范大学 | Rotary evaporator capable of accurately and quantitatively recovering multiple solvents at one time |
Non-Patent Citations (2)
| Title |
|---|
| 向丽;李迎霞;史江红;刘静玲;: "北京城区道路灰尘重金属和多环芳烃污染状况探析", 环境科学, no. 01, 15 January 2010 (2010-01-15) * |
| 马占青;温淑瑶;: "草水培生长及对富营养化水体中氮磷的净化", 水土保持学报, no. 03, 15 June 2009 (2009-06-15) * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110404282A (en) * | 2019-09-10 | 2019-11-05 | 北京师范大学 | It is a kind of can an accurate quantitative analysis recycle the Rotary Evaporators of multiple solvents |
| WO2021047537A1 (en) * | 2019-09-10 | 2021-03-18 | 北京师范大学 | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time |
| CN110404282B (en) * | 2019-09-10 | 2024-03-22 | 北京师范大学 | Rotary evaporator capable of accurately and quantitatively recycling multiple solvents at one time |
| CN110478928A (en) * | 2019-09-25 | 2019-11-22 | 北京师范大学 | It is a kind of once can accurate quantitative analysis more rotary shaft evaporimeters of multiple samples are concentrated |
| CN110478928B (en) * | 2019-09-25 | 2024-04-16 | 北京师范大学 | Multi-rotation-shaft evaporator capable of accurately and quantitatively concentrating multiple samples at one time |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110404283B (en) | 2024-03-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110404283A (en) | It is a kind of can an accurate quantitative analysis Rotary Evaporators of multiple samples are concentrated | |
| CN210845327U (en) | Rotary evaporator capable of accurately and quantitatively concentrating multiple samples at one time | |
| CN110478927B (en) | Multiple rotation axis evaporator capable of accurately and quantitatively recycling multiple solvents at one time | |
| CN110404282A (en) | It is a kind of can an accurate quantitative analysis recycle the Rotary Evaporators of multiple solvents | |
| WO2021047537A1 (en) | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time | |
| US11185791B2 (en) | Rotary evaporator capable of accurately quantifying concentrated liquid and/or distillate | |
| CN108043059B (en) | Rotary evaporator capable of accurately realizing quantification of concentrated solution | |
| CN108043058A (en) | It is a kind of accurately to realize the quantitative Rotary Evaporators of fraction | |
| CN211215487U (en) | Rotary evaporator capable of accurately and quantitatively recovering multiple solvents at one time | |
| CN210845328U (en) | Multi-rotating-shaft evaporator capable of accurately and quantitatively concentrating multiple samples at one time | |
| CN110478928B (en) | Multi-rotation-shaft evaporator capable of accurately and quantitatively concentrating multiple samples at one time | |
| CN208302236U (en) | It is a kind of accurately to realize the quantitative Rotary Evaporators of concentrate | |
| CN207187135U (en) | A kind of parallel rotating evaporates combined instrument | |
| CN106018855A (en) | Intelligent detection device for PCT chromatography and detection method of intelligent detection device | |
| CN207336460U (en) | A kind of ammonia nitrogen on-line computing model based on distillation titration method | |
| CN109395426A (en) | A kind of Rotary Evaporators suitable for chemical detection | |
| KR102390934B1 (en) | Pressure reduction concentrator using load cell | |
| CN208356140U (en) | It is a kind of accurately to realize the quantitative Rotary Evaporators of fraction | |
| EP4008418B1 (en) | Rotary evaporator for accurately and quantitatively recovering multiple solvents or concentrating multiple samples at one time | |
| CN208611821U (en) | A kind of distilling apparatus | |
| CN208420763U (en) | A kind of biliquid system vapor liquid equilibrium phasor drafting experiment ebulliometer | |
| CN207866649U (en) | A kind of measuring device of suspension surface vapour pressure | |
| CN215140063U (en) | Arsenic distillation device | |
| CN109632449A (en) | A kind of traditional Chinese drug inspissation technical process medical fluid density on-line detecting system and detection method | |
| CN219319844U (en) | Reaction kettle sampling device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |