CN110404049A - Composition and the application of cardiovascular and cerebrovascular diseases and senile dementia are prevented and treated by Neulized inhalation - Google Patents
Composition and the application of cardiovascular and cerebrovascular diseases and senile dementia are prevented and treated by Neulized inhalation Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
The invention discloses composition and applications that cardiovascular and cerebrovascular diseases and senile dementia are prevented and treated by Neulized inhalation.Prevent and/or treat the composition of cardiovascular and cerebrovascular disease and senile dementia by Neulized inhalation, include Isoflavone, vitamin C, glucityl rutin, lecithin, tripeptides -1, guluronic acid, mannuronic acid, phosphatidylserine, vitamin B12, dissolution is fabricated to the liquid of aerosolizable sucking in water.Effect is lasting deactivated after blood viscousness state recovery blood normal flow can be improved in short time of the invention and improved；Large scale hypertensive patient is quickly significantly alleviated；The cardiac's symptom generated after large scale person in middle and old age significantly mitigates；Even hemiplegia patients after years, paralysis side have begun and atrophy occur, can also the state of getting well can be normally carried out body building substantially within some months.
Description
Technical field
The present invention relates to skin care, health care, field of medical technology, prevent and treat cardiovascular and cerebrovascular diseases more particularly to by Neulized inhalation
Composition and application with senile dementia.
Background technique
Cardiovascular and cerebrovascular disease is typical disease with aging and high-incidence.The aging of system vascular and vascular wall deposition will lead to
A variety of related diseases such as thrombus, hypertension, cerebral hemorrhage, hemiplegia and physical function decline etc., these are always medicine neck
The problem in domain and mankind aging and dead major reason.
Research thinks that blood vessel aging mainly shows as being hardened and lead with many places endothelial cell damage and capillary damage
Cause permeability excessively high.These damages will lead to fibrin ferment secretion and increase, and so as to cause blood viscousness, thrombus increases.And blood simultaneously
The low density cholesterol etc. of tube wall condensation also results in thrombosis, and human body will independently increase blood to fight such case
Pressure.It is above-mentioned both to aggravate heart burden, cause wall of the heart also to will appear similar problems.The multiple functions of blood vessel decline
It will lead to and decline by the whole body body function of blood circulation maintenance metabolism, aging state in all directions occur.Extreme case is also
Meeting is died suddenly suddenly or hemiplegia, if the long-term various rehabilitation trainings of hemiplegia can not also generate recovery effects.It paralyses after hemiplegia
Lesion atrophy caused by the nervous system of the corresponding brain in position and body will appear because of blood supply stopping etc., needs to repair.
Senile dementia is many factors joint effect, and core mechanism there is no final conclusion, it is generally recognized that beta amyloid
The factors such as influence of the albumen to nerve cause, and also have anesthesia to lead to nerve damage, the factors such as VB12 absorption function forfeiture.
Summary of the invention
In order to overcome the problems of the prior art, the present invention provides prevent and treat cardiovascular and cerebrovascular diseases and old age by Neulized inhalation
Dull-witted composition and application.Prevention and treatment prevents and/or treatment, cardiovascular and cerebrovascular diseases, that is, cardiovascular and cerebrovascular disease.
The composition for preventing and/or treating cardiovascular and cerebrovascular disease and senile dementia by Neulized inhalation includes the different Huang of plant
Ketone, vitamin C, glucityl rutin, lecithin, tripeptides -1, guluronic acid, mannuronic acid, phosphatidylserine, vitamin
B12, dissolution is fabricated to the liquid of aerosolizable sucking in water.
The Isoflavone in isoflavones, genistein, Biochanin A, pueraria isoflavone one
Kind is a variety of, and total concentration is mass percent 0.5% to 5%.
The lecithin is in soybean lecithin, egg yolk lecithin, hydrogenated soy phosphatidyl choline, hydrogenated yolk lecithin
One or more.
The composition, have user's initial stage of vascular wall deposition problems in use, Lecithin Content concentration therein compared with
It is low, 0.3~0.5 gram/100 milliliters, after sense of discomfort when user uses disappears, higher concentration, 1~2 gram/100 millis can be used
It rises.
The mass percent concentration of the glucityl rutin is 0.1~10%.
The Vitamin C fraction be selected from ascorbic acid, magnesium ascorbyl phosphate, Sodium Ascorbyl Phosphate, wherein
The mass percent of Vitamin C fraction is 0.1% to 5%.
The mass percent concentration of the vitamin B12 is 100/1sts to million/1000000th or so.
Purposes of the composition in the drug of preparation prevention and/or treatment cardiovascular and cerebrovascular disease and senile dementia.
The beneficial effects of the present invention are: the effect that other treatment method is unable to reach before can produce is horizontal, such as fastly
Effect is lasting deactivated after blood viscousness state recovery blood normal flow can be improved in the fast short time and improved；Greatly
Ratio hypertensive patient is quickly significantly alleviated；The cardiac's symptom generated after large scale person in middle and old age significantly mitigates；In even
Windage yaw paralysis patients after years, paralysis side have begun and atrophy occur, can also the state of getting well can be normal substantially within some months
Carry out body building.
Specific embodiment
The present invention is further elaborated below.
The composition for preventing and/or treating cardiovascular and cerebrovascular disease and senile dementia by Neulized inhalation includes the different Huang of plant
Ketone, vitamin C, glucityl rutin, lecithin, tripeptides -1, guluronic acid, mannuronic acid, phosphatidylserine, vitamin
B12, dissolution is fabricated to the liquid of aerosolizable sucking in water.
Because breathing enters the ingredient of lung, arteries can be directly entered and be fed rapidly into heart, brain and whole body；It is right
Than it is oral be then to need by many level filterings such as alimentary canal and liver, utilization efficiency declines to a great extent；It is injected intravenously and subcutaneous
Injection can not be delivered directly to artery using being then not suitable for long-term routine use, it is still desirable to by the circulation losses of vein,
Especially brain effect is lost larger.And the harmful substance that Neulized inhalation is similar with smoking to human body and while not smoking enters,
Comparison injection is more preferable and easy to operate using obvious long-term safety.In addition, for example many peptides of many skin type functional components
Class, fermentation, which extract class, the extraction of Activities of Some Plants planktonic organism etc., can not be resistant to the digestive tract environments such as gastric acid and enteron aisle, and loss is very big,
It can not thus be worked substantially by oral；And such as vitamin B12 etc alimentary canal absorbs extremely difficult ingredient, passes through atomization and inhales
Blood can be directly entered by entering, and need not move through complicated stomach absorption processing, for leading to vitamin B12 because of functions of intestines and stomach imbalance
The user's effect that can not be absorbed is directly effective.Simultaneously in practice it has also been found that common manifestation goes out to compare mouth suction and becomes apparent from when with snuffing
Brain improvement, judgement may be that nasal cavity has and more leads to the absorptions and transportation route at brain position.
Isoflavone ingredient can produce bidirectional modulation estrogen equivalent level effect, and experiment confirms to make by Neulized inhalation
With that quickly blood vessel state can be enabled to improve, its oestrogen-like hormone effect energy fast softening blood vessel should be, and suction effect is than tradition
Oral direct action, show as causing because of nagiopasthyrosis the middle-aged and elderly users of the blood viscousness of coagulation factor hypersecretion can be with
Restore preferable blood fluidity in more than ten days and to experience blood supply smooth, especially it is observed that very specific become when blood drawing
Change, while we have found that it shows as to healthy sleep, steady mood with endocrine effect of getting well is helped, balance is complete
Body water oil, alleviating urine urgency-frequency etc. has positive effect, furthermore it is generally acknowledged that it actively has the microglia inflammatory of brain
Inhibitory effect.
For Lecithin Content in addition to the nutrition that can be used as nervous system, we have found have obviously in an experiment by Neulized inhalation
Dissolution vascular wall deposition effect, be diagnosed as vascular wall before showing as and deposit more user's initial stage use to have significant discomfort
Sense, sense of discomfort can feel that whole body is unobstructed after fading away, and the user without vascular wall deposition problems is not appointed using overall process
What sense of discomfort.
Vitamin C can promote collagen growth and eliminate free radical, help and further promote vascular health and eliminate freely
Base etc. further promotes comprehensive repair ability.
Glucityl rutin is the derived ingredient of rutin, and effect is identical as rutin, but solubility is high thus can substantially mention
It rises and uses concentration, Neulized inhalation is avoided general after capillary aging using the impervioursness that discovery can quickly repair capillary
All over the infiltration problem occurred, moreover it is possible to protect ascorbic stability, and can further promote antiradical activities and anti-inflammatory
Effect.
Tripeptides -1 is in the ingredient that skin care industry is the reparations such as traditional promotion collagen collagenous fibres epidermal cell, practice
Middle discovery also has certain effect to the reparation of vascular damaged.
Isoflavone, vitamin C, glucityl rutin, lecithin and tripeptides -1 combine Neulized inhalation use it is observed that
The significant comprehensive improvement of blood vessel state.
Guluronic acid and mannuronic acid combination are generally in skin care industry for promoting cutaneous nerve member protective factors
SAPP secretion, but it is surprising that testing Neulized inhalation judgement to promote whole body by us includes the nerve of brain
The secretion of first protective factors, to fight the injury of beta-amyloid protein (amyloid β-protein, A β), be used alone this at
Dividing Neulized inhalation is the cognitive ability promotion that can observe old dementia patients, but will appear mood deterioration simultaneously, aggressiveness increasing
It is strong to wait performance.Then we have found that it is applied in combination with Isoflavone ingredient, state of being emotionally stable can be maintained, and can be more
Restore the deep sleep ability of the elderly especially senile dementia user well, can usually accomplish to become from sleep can not be stablized
2 hours or so optimum depth sleep durations every night, have adequately research to confirm that deep sleep process deutocerebrum can reduce before this
And by the beta-amyloid protein of cerebrospinal fluid cleaning brain, and beta-amyloid protein is excessively typically considered old dementia patients
Important cause of disease.
Vitamin B12 is many old men because functions of intestines and stomach declines the vitamin that can not be absorbed, non-to maintenance neurological health
It is often important, it acts on to participate in manufacturing erythrocyte, prevents pernicious anaemia；Prevent cerebral nerve from being destroyed.It passes through stomach
Absorption is needed by complex mechanism, and functions of intestines and stomach gastrointestinal disease patient can not most probably absorb supplement, and the present invention has found in testing
Neulized inhalation can quickly see effect for the old man of vitamin B12 substantial lack, compare the injection of traditional treatment using more
Safe ready.
Phosphatidylserine has sufficiently research to confirm that nerve cell function can be improved, and adjusts the conduction of nerve impulse, increases
Into brain memory function, blood-brain barrier can be run through since it is with very strong lipophilicity, after absorption and enters brain, is played
It releives vascular smooth muscle cells, increases the effect of brain blood supply, we test confirmation and pass through the non-convention of Neulized inhalation using effect
Think.
The Isoflavone in isoflavones, genistein, Biochanin A, pueraria isoflavone one
Kind is a variety of, and total concentration is mass percent 0.5% to 5%.
The lecithin is in soybean lecithin, egg yolk lecithin, hydrogenated soy phosphatidyl choline, hydrogenated yolk lecithin
One or more.
The composition, have user's initial stage of vascular wall deposition problems in use, Lecithin Content concentration therein compared with
It is low, 0.3~0.5 gram/100 milliliters, after user use when sense of discomfort disappear after, can be used higher concentration (such as 1 gram/100 milli
It rises or higher).
The mass percent concentration of the glucityl rutin is that 0.1~10%(also can be further according to user's concrete condition
It floats up and down).
The Vitamin C fraction be selected from ascorbic acid, magnesium ascorbyl phosphate, Sodium Ascorbyl Phosphate, wherein
The mass percent of Vitamin C fraction also can further float up and down for 0.1% to 5%(according to user's concrete condition).
The mass percent concentration of the vitamin B12 (also can basis for 100/1sts to million/1000000th or so
User's concrete condition further floats up and down).
Purposes of the composition in the drug of preparation prevention and/or treatment cardiovascular and cerebrovascular disease and senile dementia.
Below in conjunction with research and development course and embodiment, the present invention is further elaborated.
In initial release, the atomized liquid of vitamin C concentration 0.5% and chick-pea tooth element A concentration 2.5% only used, it is considerable
Measure the fast quick-recovery mobility of all middle-aged and elderly users blood viscosities.The ice-cold user of trick can feel to significantly improve, and have and sleep
The problems such as dormancy, mood, urine urgency-frequency, significantly improves, most of thoroughly to have improved.
Hereafter increase -1 ingredient of tripeptides, user's blood fluidity recovery effects further mention after a period of time can be observed
It rises.
After being further added by glucityl rutin, it can be further observed that the recovery effects of blood fluidity, can generally achieve
The full general level of the health.
Then increase lecithin lipid concentration, no matter high-concentration and low-concentration is without obvious by the user that can observe no vascular wall deposition problems
Impression；And have the user of vascular wall deposition problems that can have a headache at once in very short time after Neulized inhalation starts, whole body blood
The feeling of pipe discomfort, and uncomfortable degree is directly related with lecithin lipid concentration, judgement is that vascular wall deposition appearance emulsification ablation causes
Blood flow is unbalance to be caused；The user for sense of discomfort occur can accelerate to alleviate sense of discomfort by great quantity of water drinking, and hereafter continue every
It is adhered to using sense of discomfort, which can be quickly relieved to, gradually to disappear, and can obviously feel to free circulation of the blood, and it is extensive erection hardness occur
The beneficial effect of the vascular patencies such as multiple health status.The such user in the part once lecithin of the significant larger dose of Long-term Oral before this
Have no positive effect, it is seen that Neulized inhalation, which uses, is clearly more suitble to such situation.
For hemiplegia many years user, it is observed that paralysis side starts gradually to restore certain using the atomized liquid being formulated above
Locomitivity, but cold and hot pain of tactile etc. is especially acral feeling without obviously recovery sign and cannot restore.For old
Dementia user is in a bad mood improvement and locomitivity centainly improves.Then increase alga oligosaccharides, i.e. mannuronic acid and gulose
Aldehydic acid, it may be observed that senile dementia user cognition significantly improves, and hemiplegia user tactile and cold and hot pain start to restore.
Vitamin B12 is further increased, to part senile dementia user it is observed that further improving.
Phosphatidylserine is continued growing, the further improvement of old dementia patients cognition can be observed, while hemiplegia is suffered from
Person quickly improves comprehensively.All old dementia patients for participating in test have oral vitamin B12 and phosphatidylserine before this,
There is injection vitamin B12 on a small quantity, has no positive effect.
Typical case is 4 years patients of a hemiplegia, participates in this test 67 years old this year, the entire process have about 4 months.Make
Restore locomitivity and body consciousness comprehensively with the preceding user, energy state is comprehensive to get well, and physical efficiency etc. is significant excellent
It is horizontal in mainstream of the same age.There is severe cognitive memorized orientation sense sense of equilibrium obstacle multidigit old man and persistently use three to four in other
Restore normal condition after month.
Claims (8)
1. the composition of cardiovascular and cerebrovascular diseases and senile dementia is prevented and treated by Neulized inhalation, it is characterized in that: including Isoflavone, dimension
Raw element C, glucityl rutin, lecithin, tripeptides -1, guluronic acid, mannuronic acid, phosphatidylserine, vitamin B12,
Dissolution is fabricated to the liquid of aerosolizable sucking in water.
2. composition according to claim 1, it is characterized in that: the Isoflavone is selected from isoflavones, dyestuff
One or more of lignin, Biochanin A, pueraria isoflavone, total concentration are mass percent 0.5% to 5%.
3. composition according to claim 1, it is characterized in that: the lecithin is selected from soybean lecithin, yolk lecithin
One or more of rouge, hydrogenated soy phosphatidyl choline, hydrogenated yolk lecithin.
4. composition according to claim 1, it is characterized in that: have user's initial stage of vascular wall deposition problems in use, its
In Lecithin Content concentration it is lower, 0.3~0.5 gram/100 milliliters, after user use when sense of discomfort disappear after, can be used compared with
High concentration, 1~2 gram/100 milliliters.
5. composition according to claim 1, it is characterized in that: the mass percent concentration of the glucityl rutin is
0.1~10%.
6. composition according to claim 1, it is characterized in that: the Vitamin C fraction is selected from ascorbic acid, Vitamin C
Acid phosphoric acid ester magnesium, Sodium Ascorbyl Phosphate, wherein the mass percent of Vitamin C fraction is 0.1% to 5%.
7. composition according to claim 1, it is characterized in that: the mass percent concentration of the vitamin B12 is hundred
100/1sts to million/10000th.
8. the described in any item compositions of claim 1-7 are in preparation prevention and/or treatment cardiovascular and cerebrovascular disease and senile dementia
Drug in purposes.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994322A (en) * | 1990-08-08 | 1999-11-30 | Kewpie Kabusiki Kaisya | Compositions for preventing dementia |
| CN1440240A (en) * | 2000-05-08 | 2003-09-03 | 努特里奇亚有限公司 | Preparation for prevention and/or treatment of vascular disorders |
| US20040006048A1 (en) * | 2000-03-06 | 2004-01-08 | Andras Javor | Combination of lecithin with ascorbic acid |
| CN109568252A (en) * | 2018-11-20 | 2019-04-05 | 张明 | A kind of preparation method, atomized liquid and the instructions of taking of Biochanin A solution |
-
2019
- 2019-07-23 CN CN201910666237.6A patent/CN110404049A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994322A (en) * | 1990-08-08 | 1999-11-30 | Kewpie Kabusiki Kaisya | Compositions for preventing dementia |
| US20040006048A1 (en) * | 2000-03-06 | 2004-01-08 | Andras Javor | Combination of lecithin with ascorbic acid |
| CN1440240A (en) * | 2000-05-08 | 2003-09-03 | 努特里奇亚有限公司 | Preparation for prevention and/or treatment of vascular disorders |
| CN109568252A (en) * | 2018-11-20 | 2019-04-05 | 张明 | A kind of preparation method, atomized liquid and the instructions of taking of Biochanin A solution |
Non-Patent Citations (2)
| Title |
|---|
| 余传隆等: "中国临床药物大辞典", 中国医药科技出版社, pages: 2121 * |
| 李雅萌等: "异黄酮生物活性研究进展", 特产研究, vol. 39, no. 3, pages 312 - 63 * |
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