CN110393701A - One broad sow spray and preparation method thereof - Google Patents
One broad sow spray and preparation method thereof Download PDFInfo
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- CN110393701A CN110393701A CN201910631185.9A CN201910631185A CN110393701A CN 110393701 A CN110393701 A CN 110393701A CN 201910631185 A CN201910631185 A CN 201910631185A CN 110393701 A CN110393701 A CN 110393701A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
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Abstract
The invention discloses broad sow spray and preparation method thereof, this product can replace boar, lure feelings, Cha Qing and breeding front and back for sow, it is therefore an objective to be the cross contamination for preventing farm's pig, prevent epidemic disease.The present invention includes the raw material of following parts by weight: 1-5 parts of androstenone substance, 1-5 parts of essence, 1-5 parts of sheep oil, 1-5 parts of multi-vitamins, 1000-2000 parts of alcohols solvent, 1-9 parts of cosolvent, 1-3 parts of antioxidant and 10000-20000 parts of deionized water.This product can lure oestrus of sow, effective stimulus sow property reaction, thus ovulation rate.Meanwhile in epidemic situation period, the traditional mode of feelings can be lured to avoid using boar, so that epidemic situation be blocked to propagate.
Description
Technical field
The present invention relates to pig raising field, specifically a kind of sow sprays.
Background technique
With the improvement of people ' s living standards with the increase of people's income, people can buy oneself needs many
Food, pork are exactly wherein common one kind, pork also known as globefish meat, are the meat of one of major livestocks, porcine animals domestic pig.Its property
Sweet-salty is flat, the nutritional ingredients such as protein and fat rich in, carbohydrate, calcium, iron, phosphorus.Pork is daily life
Main non-staple food, have qi-restoratives salubrity, nourishing Yin and moistening dryness, riching and moisturizing skim effect.All weak after illness, postpartum deficiency of blood, face Huang are won
Thin person can all apply to use of the product of nutritious tonifying.Pork is as one of animal food important on dining table, because fiber is more thin
Soft, connective tissue is less, and more intramuscular fat is contained in musculature, and therefore, meat flavour is especially delicious after cooking processing.
Pork has a vast market, therefore many people will cultivate main economic source of the pig as oneself, the production of sow
Son's amount is the major criterion for increasing culturist's income, could be farrowed after oestrus of sow and artificial insemination, but sow hair at present
Tense situation can be presented in sow when feelings and artificial insemination, be unwilling to cooperate artificial insemination, this reduces the pregnancy rate of sow,
To reduce the income of culturist.
Summary of the invention
The embodiment of the present invention is designed to provide a broad sow spray, mentioned above in the background art to solve
Problem.
To achieve the above object, the embodiment of the present invention provides the following technical solutions:
One broad sow spray, the raw material including following parts by weight: 1-5 parts of androstenone substance, essence 1-5
Part, 1-5 parts of sheep oil, 1-5 parts of multi-vitamins, 1000-2000 parts of alcohols solvent, 1-9 parts of cosolvent, 1-3 parts of antioxidant
With 10000-20000 parts of deionized water.
As further embodiment of the embodiment of the present invention: androstenone substance includes spreading out for androstenone and androstenone
At least one of biology.
As further embodiment of the embodiment of the present invention: multi-vitamins include VitAVitE, vitamin K, dimension
At least four in raw element B, vitamin C and vitamin D.
As further embodiment of the embodiment of the present invention: alcohols solvent includes at least one in methanol, ethyl alcohol and isopropanol
Kind.
The preparation method of the sow spray, the specific steps are as follows:
Alcohols solvent, deionized water, androstenone substance and cosolvent are mixed and are stirred evenly, obtained by step 1
To the first mixture；
Antioxidant is added into the first mixture and dissolves by heating, obtains the second mixture for step 2；
Essence, sheep oil and multi-vitamins are added into the second mixture, stirs evenly, obtains third for step 3
Mixture；
Step 4, the pH value for adjusting third mixture is 6.5-9.5, is then allowed to stand 22-26 hours, obtains semi-finished product；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
As further embodiment of the embodiment of the present invention: being stirred under 18-22 degrees Celsius of constant temperature in step 1.
As further embodiment of the embodiment of the present invention: the temperature dissolved by heating in step 2 is 55-65 degrees Celsius.
As further embodiment of the embodiment of the present invention: adjusting the pH value of third mixture in step 4 using acid binding agent.
As further embodiment of the embodiment of the present invention: acid binding agent uses sodium bicarbonate aqueous solution.
The application method of the sow spray, the specific steps are as follows: by finished product and the nose of sow keep straight line away from
From 20-100 centimetres, the nose of directly alignment sow sprays 1-2 times.
Essence and multi-vitamins can effectively improve sow to the temptation of smell, and cosolvent ensures that product is more preferably dissolved in
In liquid.This product is inflammable product, is saved at 50 degrees Celsius or less.
Compared with prior art, the beneficial effect of the embodiment of the present invention is:
This product raw material sources are extensive, are non-livestock extracts, can be to avoid viral transmission, and finished product is in artificial insemination procedures
In can be reacted with effective stimulus sow property, shrink Gilt Uterus, reduce sperm be lost, greatly improve pregnancy rate, have to sow
The good effect of pacifying, makes it more undisturbedly cooperate artificial insemination, reduces the injury to operator；
This product can stimulate oestrus of sow without boar, can help more accurately to judge sow whether heat, reduction
The amount of labour of farm employee, moreover it is possible to shorten the sow empty phase, enhance fertility；
This product can stimulate young sow to shift to an earlier date heat, and oestrus can be made to shift to an earlier date 20 days or so, and can reduce sow it
Between accuse each other behavior and tense situation, guarantee that sow cooperates artificial insemination, using effect is good.
Specific embodiment
The technical solution of the patent is explained in further detail With reference to embodiment.
Embodiment 1
One broad sow spray, the raw material including following parts by weight: 1 gram of androstenone, 1 gram of essence, sheep oil 1
Gram, 1 gram of multi-vitamins, 1000 grams of ethyl alcohol, 1 gram of cosolvent, 1 gram of antioxidant and 10000 grams of deionized water, multi-vitamins
Including vitamin A, vitamin K, vitamin B vitamin D mixture.
The preparation method of the sow spray, the specific steps are as follows:
Step 1 mixes ethyl alcohol, deionized water, androstenone and cosolvent and equal in 18 degrees Celsius of constant temperature stirrings
It is even, obtain the first mixture；
Antioxidant is added into the first mixture and dissolves in 59 degrees Centigrades, obtains the second mixing for step 2
Object；
Essence, sheep oil and multi-vitamins are added into the second mixture, stirs evenly, obtains third for step 3
Mixture；
Step 4, the pH value for adjusting third mixture is 7.5, is then allowed to stand 22 hours, obtains semi-finished product；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
The application method of the sow spray, the specific steps are as follows: by finished product and the nose of sow keep straight line away from
From 50 centimetres, the nose of directly alignment sow sprays 2 times.
Embodiment 2
One broad sow spray, the raw material including following parts by weight: 1.8 grams of derivative, the essence 1.5 of androstenone
Gram, sheep oil 1.5 grams, 2.1 grams of multi-vitamins, 1273 grams of alcohols solvent, 3.3 grams of cosolvent, 1.6 grams of antioxidant and go from
12450 grams of sub- water.Multi-vitamins include the mixture of VitAVitE, vitamin B, vitamin C and vitamin D.Alcohol
Class solvent includes the mixture of ethyl alcohol and isopropanol.
The preparation method of the sow spray, the specific steps are as follows:
Alcohols solvent, deionized water, the derivative of androstenone and cosolvent are mixed and are stirred evenly by step 1,
Obtain the first mixture；
Antioxidant is added into the first mixture and dissolves in 63 degrees Centigrades, obtains the second mixing for step 2
Object；
Essence, sheep oil and multi-vitamins are added into the second mixture, stirs evenly, obtains third for step 3
Mixture；
Step 4, the pH value for using sodium bicarbonate aqueous solution to adjust third mixture are then allowed to stand 25 hours, are obtained for 8.1
To semi-finished product；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
The application method of the sow spray, the specific steps are as follows: by finished product and the nose of sow keep straight line away from
From 25 centimetres, the nose of directly alignment sow sprays 1 time, using this product, in induction sow sexual behaviour proportion 75%.
Embodiment 3
One broad sow spray, the raw material including following parts by weight: 2.5 grams of androstenone substance, essence 2.5
Gram, 2.5 grams of sheep oil, 2.6 grams of multi-vitamins, 1530 grams of alcohols solvent, 4.7 grams of cosolvent, 2 grams of antioxidant and deionization
14869 grams of water.Androstenone substance includes the mixture of the derivative of androstenone and androstenone.Multi-vitamins include
VitAVitE, vitamin K, vitamin B, vitamin C and vitamin D mixture.Alcohols solvent includes methanol, second
The mixture of pure and mild isopropanol.
The preparation method of the sow spray, the specific steps are as follows:
Step 1 mixes alcohols solvent, deionized water, androstenone substance and cosolvent and in 20 degrees Celsius of perseverances
It is stirred evenly under temperature, obtains the first mixture；
Antioxidant is added into the first mixture and dissolves in 60 degrees Centigrades, obtains the second mixing for step 2
Object；
Essence, sheep oil and multi-vitamins are added into the second mixture, stirs evenly, obtains third for step 3
Mixture；
Step 4, the pH value for using acid binding agent to adjust third mixture are then allowed to stand 24 hours, obtain semi-finished product for 7；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
The application method of the sow spray, the specific steps are as follows: by finished product and the nose of sow keep straight line away from
From 90 centimetres, the nose of directly alignment sow sprays 2 times, using this product, in induction sow sexual behaviour proportion 82%.
Embodiment 4
One broad sow spray, the raw material including following parts by weight: 4.3 grams of androstenone, 4.5 grams of essence, sheep
4.5 grams of oil, 4.7 grams of multi-vitamins, 1870 grams of alcohols solvent, 8.2 grams of cosolvent, 2.6 grams of antioxidant and deionized water
18360 grams.
The preparation method of the sow spray, the specific steps are as follows:
Alcohols solvent, deionized water, androstenone and cosolvent are mixed and are stirred in 21 degrees Celsius of constant temperature by step 1
Uniformly, the first mixture is obtained；
Antioxidant is added into the first mixture and dissolves by heating, obtains the second mixture for step 2；
Essence, sheep oil and multi-vitamins are added into the second mixture, stirs evenly, obtains third for step 3
Mixture；
Step 4, the pH value for using acid binding agent to adjust third mixture are then allowed to stand 25 hours, obtain semi-finished product for 6.8；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
The application method of the sow spray, the specific steps are as follows: by finished product and the nose of sow keep straight line away from
From 60 centimetres, the nose of directly alignment sow sprays 2 times.
The product of embodiment 4 is used under summer heat stress: breeding rate improves 6%；Give a birth success rate improve 8% to
12%；Every nest increases by 0.5 subnumber living；Every nest reduces by 0.3 stillborn foetus number；The pig of every batch of fecund 20%.
Embodiment 5
One broad sow spray, the raw material including following parts by weight: 5 grams of androstenone substance, 5 grams of essence, silk floss
5 grams of sheep oil, 5 grams of multi-vitamins, 2000 grams of alcohols solvent, 9 grams of cosolvent, 3 grams of antioxidant and 20000 grams of deionized water.
Androstenone substance includes the mixture of the derivative of androstenone and androstenone.Multi-vitamins include vitamin E, dimension
Raw element K, vitamin B and ascorbic mixture.
The preparation method of the sow spray, the specific steps are as follows:
Step 1 mixes alcohols solvent, deionized water, androstenone substance and cosolvent and in 19 degrees Celsius of perseverances
Temperature stirs evenly, and obtains the first mixture；
Antioxidant is added into the first mixture and dissolves in 61 degrees Centigrades, obtains the second mixing for step 2
Object；
Essence, sheep oil and multi-vitamins are added into the second mixture, stirs evenly, obtains third for step 3
Mixture；
Step 4, the pH value for using pyridine to adjust third mixture are then allowed to stand 23 hours, obtain semi-finished product for 9；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
The application method of the sow spray, the specific steps are as follows: by finished product and the nose of sow keep straight line away from
From 60 centimetres, the nose of directly alignment sow sprays 2 times, using this product, in induction sow sexual behaviour proportion 68%.
Test group and contrast groups: the wean sow of other hormones is not used in East China pig farm, selection, and test group uses implementation
The product of example 5, contrast groups lure the traditional mode of feelings using boar.The wean same day is denoted as first day, and test group sow number is 113
Head, wherein 3 because other reasons eliminate, meter test number be 110.Contrast groups sow number is 97, without eliminating, the results are shown in Table 1.
Table 1
| After wean it is quiet immediately between | Test group | Oestrus rate | Contrast groups | Oestrus rate |
| Third day | 2 | 2% | ||
| 4th day | 9 | 8.18% | 19 | 19.58% |
| 5th day | 57 | 51.8% | 42 | 43.29% |
| 6th day | 31 | 28.1% | 23 | 23.7% |
| 7th day | 4 | 3.6% | 3 | 3.09% |
| 8th day | ||||
| It amounts to | 101 | 91.8% | 89 | 91.7% |
From table 1 it follows that the product of embodiment 5 is in traditional mode of the induction oestrus of sow than luring feelings using boar
Oestrus rate is high.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (8)
1. a broad sow spray, which is characterized in that the raw material including following parts by weight: 1-5 parts of androstenone substance, perfume
It is 1-5 parts of monosodium glutamate, 1-5 parts of sheep oil, 1-5 parts of multi-vitamins, 1000-2000 parts of alcohols solvent, 1-9 parts of cosolvent, anti-oxidant
1-3 parts and deionized water 10000-20000 parts of agent.
2. sow spray according to claim 1, which is characterized in that the androstenone substance includes androstene
At least one of ketone and the derivative of androstenone.
3. sow spray according to claim 1, which is characterized in that the multi-vitamins include vitamin A, dimension
At least four in raw element E, vitamin K, vitamin B, vitamin C and vitamin D.
4. sow spray according to claim 1 or 3, which is characterized in that the alcohols solvent includes methanol, ethyl alcohol
At least one of with isopropanol.
5. a kind of preparation method of the sow spray as described in claim 1-4 is any, which is characterized in that specific steps are such as
Under:
Alcohols solvent, deionized water, androstenone substance and cosolvent are mixed and are stirred evenly, obtain the by step 1
One mixture；
Antioxidant is added into the first mixture and dissolves by heating, obtains the second mixture for step 2；
Essence, sheep oil and multi-vitamins are added into the second mixture, stir evenly, obtain third mixing for step 3
Object；
Step 4, the pH value for adjusting third mixture is 6.5-9.5, is then allowed to stand 22-26 hours, obtains semi-finished product；
Step 5, semi-finished product are filled in clean spray bottle by metering, and sealing is cased to get finished product is arrived.
6. the preparation method of sow spray according to claim 5, which is characterized in that in 18- in the step 1
It is stirred under 22 degrees Celsius of constant temperature.
7. the preparation method of sow spray according to claim 5, which is characterized in that heated in the step 2 molten
The temperature of solution is 55-65 degrees Celsius.
8. the preparation method of sow spray according to claim 5 or 7, which is characterized in that adopted in the step 4
The pH value of third mixture is adjusted with acid binding agent.
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| CN201910631185.9A CN110393701A (en) | 2019-07-12 | 2019-07-12 | One broad sow spray and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910631185.9A CN110393701A (en) | 2019-07-12 | 2019-07-12 | One broad sow spray and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111467309A (en) * | 2020-04-16 | 2020-07-31 | 厦门汇承药业有限公司 | Preparation method of boar spray |
| CN112370528A (en) * | 2020-10-23 | 2021-02-19 | 宁波三生生物科技有限公司 | Pheromone composition with marking function and preparation thereof |
| CN114533740A (en) * | 2022-02-10 | 2022-05-27 | 广州威生医药科技有限公司 | Boar odorant composition and application thereof |
-
2019
- 2019-07-12 CN CN201910631185.9A patent/CN110393701A/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111467309A (en) * | 2020-04-16 | 2020-07-31 | 厦门汇承药业有限公司 | Preparation method of boar spray |
| CN112370528A (en) * | 2020-10-23 | 2021-02-19 | 宁波三生生物科技有限公司 | Pheromone composition with marking function and preparation thereof |
| CN112370528B (en) * | 2020-10-23 | 2022-04-08 | 宁波三生生物科技股份有限公司 | Pheromone composition with marking function and preparation thereof |
| CN114533740A (en) * | 2022-02-10 | 2022-05-27 | 广州威生医药科技有限公司 | Boar odorant composition and application thereof |
| CN114533740B (en) * | 2022-02-10 | 2024-04-12 | 广州威生医药科技有限公司 | Boar odorant composition and application thereof |
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