CN110387320A - A kind of full-automatic primary cell separator - Google Patents
A kind of full-automatic primary cell separator Download PDFInfo
- Publication number
- CN110387320A CN110387320A CN201810354814.3A CN201810354814A CN110387320A CN 110387320 A CN110387320 A CN 110387320A CN 201810354814 A CN201810354814 A CN 201810354814A CN 110387320 A CN110387320 A CN 110387320A
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- China
- Prior art keywords
- workbench
- full
- primary cell
- cell separator
- bracket
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims abstract description 26
- 230000007246 mechanism Effects 0.000 claims abstract description 18
- 238000000926 separation method Methods 0.000 abstract description 4
- 238000011109 contamination Methods 0.000 abstract description 2
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 23
- 238000010586 diagram Methods 0.000 description 10
- 230000000694 effects Effects 0.000 description 5
- 238000000034 method Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000004113 cell culture Methods 0.000 description 1
- 238000012864 cross contamination Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 210000003954 umbilical cord Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a kind of full-automatic primary cell separators, including workbench and controller, the workbench is equipped with bracket, the bracket is equipped with knife rest, the knife rest is connect with bracket slide, the knife rest is equipped with more pieces of blades, sliding rail is additionally provided on the workbench, the sliding rail is equipped with objective table and is slidably connected with objective table, the objective table is equipped with the pedestal placed for tissue, the bracket is equipped with the first power mechanism for sliding with movable knife rack, the workbench is equipped with the second power mechanism for sliding with dynamic object stage, first power mechanism is electrically connected with the controller with the second power mechanism, the bottom of the workbench is additionally provided with multiple support legs and multiple universal wheels.Beneficial effects of the present invention: using this structure, and user, which can only need to be placed into cell tissue on objective table, to be cut automatically, and cutting efficiency is higher, and the tissue consistency after separation is higher, and is not easy contamination of cells tissue.
Description
Technical field
The application belongs to technical field of cell culture, specifically, being related to a kind of full-automatic primary cell separator.
Background technique
The prior art has some cell tissues, such as umbilical cord mesenchymal stem cells, be all separated by manpower work, but
It is that this mode of operation has the disadvantages that, 1, using manual operation, larger workload, and also efficiency is lower；2, it is manually operated,
User's hand is easy to touch tissue, so that pollution risk is larger；3, it is not of uniform size that isolated tissue is manually operated, consistency compared with
Difference, what some were separated not can be carried out culture even.
Summary of the invention
In view of this, the technical problem to be solved by the application is to provide provide a kind of separating effect efficiency it is higher and imitate
The preferably full-automatic primary cell separator of fruit.
In order to solve the above-mentioned technical problem, this application discloses a kind of full-automatic primary cell separators, including workbench
With controller, the workbench is equipped with bracket, and the bracket is equipped with knife rest, and the knife rest is connect with bracket slide, described
Knife rest is equipped with more pieces of blades, and sliding rail is additionally provided on the workbench, and the sliding rail is equipped with objective table and slides with objective table
Connection, the objective table are equipped with the pedestal placed for tissue, and the bracket is dynamic equipped with first for sliding with movable knife rack
Force mechanisms, the workbench are equipped with the second power mechanism for sliding with dynamic object stage, first power mechanism and the
Two power mechanisms are electrically connected with the controller, and the bottom of the workbench is additionally provided with multiple support legs and multiple universal wheels.
Using the above structure compared with prior art, the application has the following advantages: using this structure, user can only be needed
Cell tissue, which is placed on objective table, to cut automatically, and cutting efficiency is higher, and the tissue after separation is consistent
Property is higher, and is not easy contamination of cells tissue.
As preferred: being additionally provided with screw motor on the workbench, the shaft with screw motor is equipped in the support leg
Compatible nut, the nut are equipped with guide rod, and the workbench is equipped with guide groove compatible with the guide rod,
The nut and guide rod are integrally formed, and the screw motor is electrically connected with the controller, and control workbench liter by screw motor
Drop, facilitates the movement and placement of workbench.
As preferred: being additionally provided with driving motor on the workbench, the driving motor is embedded in workbench and shaft
It is equipped with nut equipped with the first helical gear, in the support leg and is connect by bolt with workbench, the bolt is equipped with and is used for
Drive the driving gear of bolt rotation, the workbench be equipped with the second helical gear for being meshed of driving gear, described first
Helical gear is connect with the second helical gear by rod failure gear, is connected between the driving gear by gear set, the support leg
It is equipped with guide post, the workbench is equipped with the sliding slot to match with guide post, and the guide post and sliding slot are integrally formed, institute
Driving motor is stated to be electrically connected with the controller.By the lifting of all support legs of motor control, worktable lifting is improved
Reliability.
Preferably, it further includes the cover board for covering the tissue being placed on pedestal, cover board is snapped connection with pedestal,
And cover board is equipped with the through-hole for matching with blade and passing through for blade.One cover board is set, can will be placed on pedestal in this way
Cell tissue cover, prevent from causing separating effect poor because cell tissue is rolled.
Preferably, pedestal is equipped with the protrusion cooperated with through-hole.In this way, blade carry out cutting separation when effect more
It is good.
Preferably, pedestal and the removable connection of objective table.It can be convenient in this way when separating different cell tissues
Pedestal is replaced, cross contamination is prevented.
Preferably, the cross section of blade is hollow rectangle.The tissue that such blade cutting is separated can be more preferable
Carry out cultivate.
Detailed description of the invention
The drawings described herein are used to provide a further understanding of the present application, constitutes part of this application, this Shen
Illustrative embodiments and their description please are not constituted an undue limitation on the present application for explaining the application.In the accompanying drawings:
Fig. 1 is the structural schematic diagram of the full-automatic primary cell separator of the application.
Fig. 2 is the structural schematic diagram that the full-automatic primary cell separator of the application is merely able to blade.
Fig. 3 is the structural schematic diagram of pedestal in the new automatic primary cell separator of the application.
Fig. 4 is the structural schematic diagram of the full-automatic primary cell separator cover plate of the application.
Fig. 5 is the structural schematic diagram of full-automatic 1 workbench of primary cell separator embodiment of the application.
Fig. 6 is the lifting schematic diagram of full-automatic 1 workbench of primary cell separator embodiment of the application.
Fig. 7 is the lifting structure schematic diagram of full-automatic 1 workbench of primary cell separator embodiment of the application.
Fig. 8 is the structural schematic diagram of full-automatic 2 workbench of primary cell separator embodiment of the application.
Fig. 9 is the lifting schematic diagram of full-automatic 2 workbench of primary cell separator embodiment of the application.
Figure 10 is the lifting structure schematic diagram of full-automatic 2 workbench of primary cell separator embodiment of the application.
Description of symbols in figure: 1, workbench；2, bracket；3, knife rest；4, blade；5, sliding rail；6, objective table；7, pedestal；8,
Cover board；9, through-hole；10, raised, 11, support leg, 12, universal wheel, 13, screw motor.
Specific embodiment
Presently filed embodiment is described in detail below in conjunction with accompanying drawings and embodiments, how the application is applied whereby
Technological means solves technical problem and reaches the realization process of technical effect to fully understand and implement.
Embodiment 1: as shown in Figures 1 to 7, a kind of full-automatic primary cell separator, including workbench 1 and controller,
Workbench 1 is equipped with bracket 2, and bracket 2 is equipped with knife rest 3, and knife rest 3 is slidably connected with bracket 2, and glide direction is vertical side
To knife rest 3 is equipped with more pieces of blades 4, and sliding rail 5 is additionally provided on workbench 1, and sliding rail 5 is equipped with objective table 6 and slides with objective table 6
Dynamic connection, glide direction is vertical with the glide direction of bracket 2, and objective table 6 is equipped with the pedestal 7 placed for tissue, sets on bracket 2
There is the first power mechanism for driving knife rest 3 to slide, workbench 1 is equipped with the second power for sliding with dynamic object stage 6
Mechanism, the first power mechanism are electrically connected with the controller with the second power mechanism, and the bottom of workbench 1 is additionally provided with multiple support legs
11 with multiple universal wheels 12.
Wherein the first power mechanism and the second power mechanism can use cylinder, and then controller can select electromagnetism
Valve controls the movement of cylinder by solenoid valve.
It further includes the cover board 8 for covering the tissue being placed on pedestal, and cover board 8 is snapped connection with pedestal 7, and cover board
8 are equipped with the through-hole 9 for matching with blade 4 and passing through for blade.Pedestal 7 is equipped with the protrusion 10 cooperated with through-hole 9.Pedestal 7 with
The removable connection of objective table 6.Removable connection is mainly connected by a snap herein.The cross section of blade 4 is hollow rectangle.
Screw motor 13 is additionally provided on workbench 1, screw motor is inverted on workbench 1, and it is pre- that shaft is set to workbench 1
In the through-hole stayed, for the fixed effect of lifting handle motor 13, screw motor 13 is externally provided with mounting shell, and mounting shell passes through bolt
It is fixed on workbench 1, nut compatible with the shaft of screw motor 13 is equipped in support leg 11, is additionally provided with and leads on nut
To stick, workbench 1 is equipped with guide groove compatible with guide rod, and nut and guide rod are integrally formed.
Embodiment 2: as seen in figs. 8-10, being additionally provided with driving motor on workbench 1, driving motor be embedded in workbench 1 and
Shaft is equipped with the first helical gear, and nut is equipped in support leg 11 and is connect by bolt with workbench 1, bolt is equipped with and is used for
The driving gear of bolt rotation is driven, driving gear is arranged between workbench 1 and support leg 11, and workbench 1 is also equipped with the
Two helical gears, the second helical gear are divided into two parts, upper part up and down and are connect with the first helical gear by rod failure gear, lower part
It is meshed with driving gear, drives and connected between gear by gear set, support leg 11 is equipped with guide post, sets on workbench 1
There is the sliding slot to match with guide post, guide post and sliding slot are integrally formed.
When needing transfer table, by controller control screw motor counter-rotating, nut drive support leg 11 to
Upper movement, at this moment universal wheel moves down until contact ground, after support leg 11 moves upwards a certain distance, universal wheel 12 is right
Workbench 1 plays main supporting role, starts mobile work platform 1, and after workbench 1 completes transfer, controller controls screw rod electricity
Machine rotates in the forward direction, and nut drives support leg 11 to move downward, and after support leg 11 moves downwardly to contact ground, continues fortune downwards
Dynamic, universal wheel 12 is detached from ground, and support leg 11 plays main supporting role to workbench 1.
The application concrete operating principle is, first need to cell tissue to be separated be placed on pedestal, then cover cover board,
And cover board is fastened on pedestal, then controller control objective table is moved to disengaged position, and control knife rest is past later moves down
It is dynamic, the cell tissue being placed on pedestal is cut, primary structure separation is completed.
Several preferred embodiments of the invention have shown and described in above description, but as previously described, it should be understood that the present invention
Be not limited to forms disclosed herein, should not be regarded as an exclusion of other examples, and can be used for various other combinations,
Modification and environment, and the above teachings or related fields of technology or knowledge can be passed through within that scope of the inventive concept describe herein
It is modified.And changes and modifications made by those skilled in the art do not depart from the spirit and scope of the present invention, then it all should be in this hair
In the protection scope of bright appended claims.
Claims (7)
1. a kind of full-automatic primary cell separator, including workbench (1) and controller, the workbench (1) is equipped with bracket
(2), it is characterised in that: the bracket (2) is equipped with knife rest (3), and the knife rest (3) is slidably connected with bracket (2), the knife rest
(3) more pieces of blades (4) are equipped with, are additionally provided with sliding rail (5) on the workbench (1), the sliding rail (5) is equipped with objective table (6)
And be slidably connected with objective table (6), the objective table (6) is equipped with the pedestal (7) placed for tissue, sets on the bracket (2)
There is the first power mechanism for driving knife rest (3) to slide, the workbench (1) is equipped with to be slided for band dynamic object stage (6)
The second power mechanism, first power mechanism is electrically connected with the controller with the second power mechanism, the workbench (1)
Bottom is additionally provided with multiple support legs (11) and multiple universal wheels (12).
2. full-automatic primary cell separator according to claim 1, it is characterised in that: also set on the workbench (1)
Have screw motor (13), nut compatible with the shaft of screw motor (13), the nut are equipped in the support leg (11)
It is equipped with guide rod, the workbench (1) is equipped with guide groove compatible with the guide rod, the nut and guide rod one
Body formed, the screw motor (13) is electrically connected with the controller.
3. full-automatic primary cell separator according to claim 1, it is characterised in that: also set on the workbench (1)
There is driving motor, the driving motor is embedded in workbench (1) and shaft is equipped with the first helical gear, and the support leg (11) is interior
It is connect equipped with nut and by bolt with workbench (1), the bolt is equipped with the driving gear for driving bolt to rotate, institute
It states workbench (1) and is equipped with the second helical gear being meshed with driving gear, first helical gear passes through with the second helical gear
Rod failure gear connects, and is connected between the driving gear by gear set, and the support leg (11) is equipped with guide post, the work
Make platform (1) and be equipped with the sliding slot to match with guide post, the guide post and sliding slot are integrally formed, the driving motor and control
Device electrical connection.
4. full-automatic primary cell separator according to claim 1, it is characterised in that: it further includes placing for covering
The cover board (8) of tissue on pedestal, the cover board (8) snaps connection with pedestal (7), and the cover board (8) is equipped with and knife
The through-hole (9) that piece (4) is matched and passed through for blade.
5. full-automatic primary cell separator according to claim 4, it is characterised in that: the pedestal (7) be equipped with
The protrusion (10) of through-hole (9) cooperation.
6. full-automatic primary cell separator according to claim 1, it is characterised in that: the pedestal (7) and objective table
(6) removable connection.
7. full-automatic primary cell separator according to claim 1, it is characterised in that: the cross section of the blade (4)
For hollow rectangle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810354814.3A CN110387320A (en) | 2018-04-19 | 2018-04-19 | A kind of full-automatic primary cell separator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810354814.3A CN110387320A (en) | 2018-04-19 | 2018-04-19 | A kind of full-automatic primary cell separator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110387320A true CN110387320A (en) | 2019-10-29 |
Family
ID=68283343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810354814.3A Pending CN110387320A (en) | 2018-04-19 | 2018-04-19 | A kind of full-automatic primary cell separator |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110387320A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110919706A (en) * | 2019-11-01 | 2020-03-27 | 上海蓓蕊医疗科技有限公司 | Cell precision cutting device and use method thereof |
| WO2023181636A1 (en) * | 2022-03-23 | 2023-09-28 | 富士フイルム株式会社 | Cell isolation method and cell isolation apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2753559Y (en) * | 2004-12-21 | 2006-01-25 | 肖庆元 | Stone-imitating moulding machine |
| RU2371307C1 (en) * | 2008-06-04 | 2009-10-27 | Открытое Акционерное Общество "Корпорация Всмпо-Ависма" | Device for cutting of refractory metal block |
| CN203034286U (en) * | 2012-12-28 | 2013-07-03 | 上海工程技术大学 | Device for cutting fabrics of sample cards |
| CN105058832A (en) * | 2015-08-17 | 2015-11-18 | 苏州瑞日纺织科技有限公司 | Pouring device for shoemaking |
| CN206536533U (en) * | 2017-02-23 | 2017-10-03 | 闫宣 | A kind of medical Chinese medicine for losing weight material, which makes, uses hawthorn slicing device |
| CN208234906U (en) * | 2018-04-19 | 2018-12-14 | 何加铭 | A kind of full-automatic primary cell separator |
-
2018
- 2018-04-19 CN CN201810354814.3A patent/CN110387320A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2753559Y (en) * | 2004-12-21 | 2006-01-25 | 肖庆元 | Stone-imitating moulding machine |
| RU2371307C1 (en) * | 2008-06-04 | 2009-10-27 | Открытое Акционерное Общество "Корпорация Всмпо-Ависма" | Device for cutting of refractory metal block |
| CN203034286U (en) * | 2012-12-28 | 2013-07-03 | 上海工程技术大学 | Device for cutting fabrics of sample cards |
| CN105058832A (en) * | 2015-08-17 | 2015-11-18 | 苏州瑞日纺织科技有限公司 | Pouring device for shoemaking |
| CN206536533U (en) * | 2017-02-23 | 2017-10-03 | 闫宣 | A kind of medical Chinese medicine for losing weight material, which makes, uses hawthorn slicing device |
| CN208234906U (en) * | 2018-04-19 | 2018-12-14 | 何加铭 | A kind of full-automatic primary cell separator |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110919706A (en) * | 2019-11-01 | 2020-03-27 | 上海蓓蕊医疗科技有限公司 | Cell precision cutting device and use method thereof |
| WO2023181636A1 (en) * | 2022-03-23 | 2023-09-28 | 富士フイルム株式会社 | Cell isolation method and cell isolation apparatus |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20191029 |