CN110384616B - Antibacterial complete denture and manufacturing method thereof - Google Patents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
- A61K6/35—Preparations for stabilising dentures in the mouth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/70—Preparations for dentistry comprising inorganic additives
- A61K6/71—Fillers
- A61K6/76—Fillers comprising silicon-containing compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
- A61K6/887—Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
- A61K6/891—Compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
- A61K6/896—Polyorganosilicon compounds
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Abstract
The invention discloses an antibacterial complete denture and a manufacturing method thereof, and the antibacterial complete denture comprises an artificial tooth and a base, wherein the base comprises the following components in parts by weight: 70-80 parts of denture powder, 30-40 parts of denture water, 2-3 parts of silicon toughener, 4-8 parts of silver-loaded silicon dioxide, 2-4 parts of natural antibacterial agent and 1-2 parts of nano titanium dioxide. According to the invention, the silver-loaded silicon dioxide, the nano titanium dioxide and the natural antibacterial agent are compounded, so that the base has excellent antibacterial performance, and the toughness of the base can be further improved by compounding the silver-loaded silicon dioxide, the nano titanium dioxide and the silicon toughening agent, so that the service life of the base is prolonged.
Description
Technical Field
The invention relates to the technical field of denture materials, in particular to an antibacterial complete denture and a manufacturing method thereof.
Background
The denture is a general term for a prosthesis made after partial or all teeth of the upper and lower jaws are lost in medicine, namely, a denture is a traditional Chinese medicine; complete dentures are the conventional repair treatment for edentulous patients. The complete denture is a removable denture prosthesis which adopts artificial materials to replace missing complete dentition of upper jaw or lower jaw and related tissues; the complete denture is composed of an artificial tooth and a base, the denture is adsorbed on the alveolar ridges of the upper jaw and the lower jaw by means of the adsorption force and the atmospheric pressure generated by the close attachment and the edge sealing of the denture base and the non-dentognathic mucosal tissue, the defective tissue and the facial appearance of a patient are recovered, the chewing and pronunciation functions are recovered, and the periosteum and the bone tissue covered by the denture base bear the occlusion pressure of the denture.
The base is usually made of resin, and the base resin is generally composed of two parts of powder and liquid, wherein the powder is sold under the trade name of denture powder, the main component of the powder is homopolymerized powder or copolymer powder of methyl methacrylate, and the main component of the denture water is methyl methacrylate. The manufacturing method of the denture base generally adopts the following method: mixing denture powder and denture water at a certain ratio to swell the denture powder particles to form dough-like plastic, filling the plastic into a female cavity of a denture in a mold box, and performing free radical polymerization at 68-74 ℃ to form the denture base.
When the complete denture is worn, the base can be tightly attached to the denture, and the attached part of the denture is easy to become a hotbed for breeding microbes such as bacteria and fungi due to less saliva, so that food residues retained on the denture can provide nutrient substances for the microbes, plaque can be easily formed on the denture, and the service life of the denture is shortened; for the old with poor resistance, oral inflammation and other diseases are more easily caused; when a patient uses a new denture, the patient needs to have a certain running-in period with the denture to gradually overcome discomfort, and compared with the old, the patient is weaker in constitution and poorer in oral environment, and even can feel discomfort of nausea and vomiting when wearing the new denture, so that the times of replacing the denture by the old are reduced as much as possible; in the process of manufacturing the base of the traditional false tooth, due to internal stress during heat treatment of the base, micro cracks or cracks are generated inside and on the surface of the base, the false tooth is easy to break after long-time use, and the service life of the false tooth is shortened; therefore, if the complete denture with excellent antibacterial performance and long service life is prepared, the problem needs to be solved.
Disclosure of Invention
One of the purposes of the invention is to provide an antibacterial complete denture, which has excellent antibacterial performance through compounding silver-loaded silicon dioxide, nano titanium dioxide and a natural antibacterial agent, and can further improve the toughness of the denture by compounding the silver-loaded silicon dioxide, the nano titanium dioxide and a silicon toughening agent, thereby prolonging the service life of the denture.
The technical purpose of the invention is realized by the following technical scheme:
an antibacterial complete denture comprises an artificial tooth and an abutment, wherein the abutment comprises the following components in parts by weight: 70-80 parts of denture powder, 30-40 parts of denture water, 2-3 parts of silicon toughener, 4-8 parts of silver-loaded silicon dioxide, 2-4 parts of natural antibacterial agent and 1-2 parts of nano titanium dioxide.
By adopting the technical scheme, the base has excellent antibacterial performance by compounding the silver-loaded silicon dioxide, the nano titanium dioxide and the natural antibacterial agent, and the toughness of the base can be further improved by compounding the silver-loaded silicon dioxide, the nano titanium dioxide and the silicon-based toughening agent, so that the service life of the base is prolonged.
Further, the silver-loaded silica is prepared by adopting the following method:
the preparation method comprises the following steps: taking 20-30 parts of silicon dioxide, 1-2 parts of titanium dioxide and 0.6-1 part of zirconium dioxide, grinding the silicon dioxide, calcining the silicon dioxide, the titanium dioxide and the zirconium dioxide at the temperature of 900-950 ℃, and cooling the silicon dioxide, the titanium dioxide and the zirconium dioxide to obtain a calcined material;
secondly, 0.2-0.3 part of silver nitrate powder is taken, 30 parts of water is added into the silver nitrate powder, and the mixture is uniformly stirred to obtain silver nitrate solution; adding 2-4 parts of calcined material into silver nitrate solution, and stirring at 20-30 deg.C for 10-20min to obtain mixed solution;
③ adding 0.2 to 0.4 portion of glucose and 1 to 2 portions of 10 weight percent aqueous solution of sodium hydroxide into the mixed solution, stirring for 10 to 20min, and obtaining the silver-carrying silicon dioxide after suction filtration, washing and drying.
By adopting the technical scheme, the silicon dioxide is of a porous structure, and after the silicon dioxide, the titanium dioxide and the silicon dioxide are calcined, the adsorption performance of the silicon dioxide can be improved, the silver-carrying amount of the silicon dioxide is improved, so that the prepared silver-carrying silicon dioxide has better chemical stability, antibacterial durability and biocompatibility.
Furthermore, the drying temperature in the third step is 80-90 ℃, and the drying time is 6-8 h.
Further, the natural antibacterial agent is prepared by mixing a reed rhizome extract, an eucommia ulmoides leaf extract and tea polyphenol in a weight ratio of 3:1: 1.
By adopting the technical scheme, the eucommia ulmoides leaf extract and the tea polyphenol have good antibacterial and anti-inflammatory effects, the natural antibacterial agent obtained by compounding the reed rhizome extract, the eucommia ulmoides leaf extract and the tea polyphenol is safer, and the complete denture prepared from the natural antibacterial agent has good early-stage antibacterial ability, can relieve nausea and vomiting feeling of the complete denture worn by a patient for the first time, relieve oral odor and improve the oral environment of the patient.
Further, the silicon toughening agent polymethyl methacrylate-organic siloxane-acrylate core-shell copolymer.
By adopting the technical scheme, the polymethyl methacrylate-organosiloxane-acrylate core-shell copolymer has excellent toughening effect, and has better compatibility with denture powder, and in the heat treatment process of the denture, the silicon series toughening agent has better dispersibility, can reduce the generation of cracks, effectively improves the toughness of the denture and prolongs the service life of the denture.
Further, the denture powder comprises the following components in parts by weight: the denture powder comprises the following components in parts by weight: 90-100 parts of polymethyl methacrylate and 1-2 parts of benzoyl peroxide initiator.
Further, the denture water comprises the following components in parts by weight: 80-90 parts of methyl methacrylate, 0.3-0.5 part of accelerator and 0.6-0.32 part of UV-3200.4.
Further, the accelerator is sodium p-toluenesulfinate.
By adopting the technical scheme, the chemical property of the sodium p-toluenesulfinate is relatively stable, and the color stability of the base can be improved.
The second purpose of the invention is to provide a manufacturing method of the antibacterial complete denture.
The technical purpose of the invention is realized by the following technical scheme:
a manufacturing method of an antibacterial complete denture comprises the following steps:
(1) preparing denture powder: taking 90-100 parts of polymethyl methacrylate and 1-2 parts of benzoyl peroxide initiator by weight parts, and uniformly stirring to obtain denture powder;
(2) preparing denture base water: taking 80-90 parts of methyl methacrylate, 0.3-0.5 part of accelerant and 0.6-0.3 part of UV-3200.4, and uniformly stirring to obtain denture fixing water;
(3) preparation of a base: uniformly stirring 70-80 parts of denture powder, 2-3 parts of silicon toughener, 4-8 parts of silver-loaded silicon dioxide, 6-8 parts of nano titanium dioxide and 2-4 parts of natural antibacterial agent to obtain a mixture, adding 30-40 parts of denture water into the mixture, stirring for 20min, and placing the mixture into a mold after the mixture is agglomerated; then placing the mould at the temperature of 70-75 ℃, and heating in a constant-temperature water bath for 90-120 min; heating to 100 deg.C, and heating at constant temperature for 40-60min to obtain cured base;
(4) preparing complete dentures: and mounting the artificial teeth on the base to obtain the complete denture.
In summary, compared with the prior art, the invention has the following beneficial effects:
1. the base has excellent antibacterial performance by compounding the silver-loaded silicon dioxide, the nano titanium dioxide and the natural antibacterial agent, and the toughness of the base can be further improved by compounding the silver-loaded silicon dioxide, the nano titanium dioxide and the silicon toughening agent, so that the service life of the base is prolonged;
2. the silicon dioxide is of a porous structure, and after the silicon dioxide, the titanium dioxide and the silicon dioxide are calcined, the adsorption performance of the silicon dioxide can be improved, the silver-carrying amount of the silicon dioxide is increased, and the prepared silver-carrying silicon dioxide has better chemical stability, antibacterial durability and biocompatibility;
3. the eucommia ulmoides leaf extract and the tea polyphenol have good antibacterial and anti-inflammatory effects, the natural antibacterial agent obtained by compounding the reed rhizome extract, the eucommia ulmoides leaf extract and the tea polyphenol is safer, and the complete denture prepared from the natural antibacterial agent has good early-stage antibacterial capability, can relieve nausea and vomiting feeling of wearing the complete denture for the first time by a patient, relieve peculiar smell of the oral cavity and improve the oral environment of the patient;
4. the polymethyl methacrylate-organic siloxane-acrylate core-shell copolymer has an excellent toughening effect, has good compatibility with denture powder, has good dispersibility in the heat treatment process of the denture, can reduce the generation of cracks, effectively improves the toughness of the denture and prolongs the service life of the denture.
Detailed Description
The present invention will be described in further detail below.
Preparation of silver-loaded silica
Preparation example 1: grinding 20kg of silicon dioxide, 1kg of titanium dioxide and 0.6kg of zirconium dioxide, calcining at 900 ℃ for 4 hours, and cooling to obtain a calcined material;
② taking 0.2kg of silver nitrate powder, adding 30kg of water into the silver nitrate powder, and uniformly stirring to obtain silver nitrate solution; adding 2kg of calcined material into silver nitrate solution, and stirring at 20-30 ℃ for 10min to obtain mixed solution;
③ adding 0.2kg of glucose and 1kg of 10wt% sodium hydroxide aqueous solution into the mixed solution, stirring for 10min, filtering, washing by 50 wt% ethanol solution, and drying at 80 ℃ for 6h to obtain the silver-loaded silicon dioxide.
Preparation example 2: taking 25kg of silicon dioxide, 1.5kg of titanium dioxide and 0.8kg of zirconium dioxide, grinding the silicon dioxide, calcining the silicon dioxide and the titanium dioxide at the temperature of 925 ℃ for 5 hours, and cooling to obtain a calcined material;
② taking 0.25kg of silver nitrate powder, adding 30kg of water into the silver nitrate powder, and uniformly stirring to obtain silver nitrate solution; adding 3kg of calcined material into the silver nitrate solution, and stirring for 15min at the temperature of 25 ℃ to obtain a mixed solution;
③ adding 0.3kg of glucose and 1.5kg of 10wt% sodium hydroxide aqueous solution into the mixed solution, stirring for 15min, filtering, washing by 50 wt% ethanol solution, and drying for 7h at 85 ℃ to obtain the silver-loaded silicon dioxide.
Preparation example 3: grinding 30kg of silicon dioxide, 2kg of titanium dioxide and 1kg of zirconium dioxide, calcining at 950 ℃ for 6 hours, and cooling to obtain a calcined material;
② taking 0.3kg of silver nitrate powder, adding 30kg of water into the silver nitrate powder, and uniformly stirring to obtain silver nitrate solution; adding 4kg of calcined material into silver nitrate solution, and stirring for 20min at the temperature of 30 ℃ to obtain mixed solution;
③ adding 0.4kg of glucose and 2kg of 10wt% sodium hydroxide aqueous solution into the mixed solution, stirring for 20min, filtering, washing with 50 wt% ethanol solution, and drying at 90 ℃ for 8h to obtain the silver-loaded silicon dioxide.
Preparation example 4: this preparation example is different from preparation example 1 in that titanium dioxide and zirconium dioxide are not contained in step (i).
Preparation example 5: this production example is different from production example 1 in that the silica was not subjected to the calcination treatment of step (i).
Second, example
The polymethacrylic acid in the following examples is selected from the group consisting of polymethylmethacrylate supplied by Wuhan Seisan co-creation technologies, Inc. under the model number 9011-14-7; the silicon flexibilizer is selected from polymethyl methacrylate-organic siloxane-acrylate core-shell copolymer provided by Mitsubishi Yang and having the model number of S-2030; the rhizoma Phragmitis extract is selected from rhizoma Phragmitis extract provided by Yuancheng group at a content ratio of 10: 1; the folium Eucommiae extract is selected from folium Eucommiae extract provided by Yuancheng group at a content ratio of 10: 1; the tea polyphenols are selected from food grade tea polyphenols provided by Raido corporation.
Example 1: the antibacterial complete denture is prepared by adopting the following method:
(1) preparing denture powder: taking 90kg of polymethyl methacrylate and 1kg of benzoyl peroxide initiator, and uniformly stirring to obtain denture powder;
(2) preparing denture base water: taking 80kg of methyl methacrylate, 0.3kg of sodium p-toluenesulfinate accelerator and 0.8978 kg of UV-3200.4 kg, and uniformly stirring to obtain denture solution;
(3) preparation of a base: taking 70kg of denture powder, 2kg of silicon-based flexibilizer, 4kg of silver-loaded silicon dioxide (selected from preparation example 1), 6kg of nano titanium dioxide and 2kg of natural antibacterial agent formed by mixing reed rhizome extract, eucommia bark leaf extract and tea polyphenol in a weight ratio of 3:1:1, uniformly stirring to obtain a mixture, adding 30kg of denture water into the mixture, stirring for 20min, and placing the mixture into a mold after the mixture is agglomerated; then placing the mould at the temperature of 70 ℃, and heating in a constant-temperature water bath for 90 min; heating to 100 deg.C, and heating at constant temperature for 40min to obtain cured base;
(4) preparing complete dentures: and mounting the artificial teeth on the base to obtain the complete denture.
Example 2: the antibacterial complete denture is prepared by adopting the following method:
(1) preparing denture powder: taking 95kg of polymethyl methacrylate and 1.5kg of benzoyl peroxide initiator, and uniformly stirring to obtain denture powder;
(2) preparing denture base water: taking 85kg of methyl methacrylate, 0.4kg of p-toluenesulfinic sodium accelerator and UV-3200.5 kg, and uniformly stirring to obtain denture water;
(3) preparation of a base: taking 75kg of denture powder, 2.5kg of silicon-based flexibilizer, 6kg of silver-loaded silicon dioxide (selected from preparation example 2), 7kg of nano titanium dioxide and 3kg of natural antibacterial agent prepared by mixing reed rhizome extract, eucommia leaf extract and tea polyphenol in a weight ratio of 3:1:1, uniformly stirring to obtain a mixture, adding 35kg of denture water into the mixture, stirring for 20min, and placing the mixture into a mold after the mixture is agglomerated; then placing the mould at 73 ℃, and heating in a constant-temperature water bath for 100 min; heating to 100 deg.C, and heating at constant temperature for 50min to obtain cured base;
(4) preparing complete dentures: and mounting the artificial teeth on the base to obtain the complete denture.
Example 3: the antibacterial complete denture is prepared by adopting the following method:
(1) preparing denture powder: taking 100kg of polymethyl methacrylate and 2kg of benzoyl peroxide initiator, and uniformly stirring to obtain denture powder;
(2) preparing denture base water: taking 90kg of methyl methacrylate, 0.5kg of sodium p-toluenesulfinate accelerator and 0.8978 kg of UV-3200.6 kg, and uniformly stirring to obtain denture fixing water;
(3) preparation of a base: uniformly stirring 80kg of denture powder, 3kg of silicon-based flexibilizer, 8kg of silver-loaded silicon dioxide (selected from preparation example 3), 8kg of nano titanium dioxide and 4kg of natural antibacterial agent formed by mixing reed rhizome extract, eucommia bark leaf extract and tea polyphenol in a weight ratio of 3:1:1 to obtain a mixture, adding 40kg of denture water into the mixture, stirring for 20min, and placing the mixture into a mold after the mixture is agglomerated; then placing the mould at the temperature of 75 ℃, and heating in a constant-temperature water bath for 120 min; heating to 100 deg.C, and heating at constant temperature for 60min to obtain cured base;
(4) preparing complete dentures: and mounting the artificial teeth on the base to obtain the complete denture.
Third, comparative example
Comparative example 1: this comparative example differs from example 1 in that the raw material of the base does not contain a natural antibacterial agent.
Comparative example 2: this comparative example is different from example 1 in that the silver-loaded silica in the raw material of the susceptor was selected from those obtained in preparation example 4, and in that titanium dioxide and zirconium dioxide were not included in step (r) in the preparation process.
Comparative example 3: this production example is different from production example 1 in that the silver-loaded silica in the raw material of the susceptor was selected from those obtained in production example 5, the silica was not subjected to the calcination treatment of step (i) in the production process, and the raw material contained no titanium dioxide and zirconium dioxide.
Fourthly, performance test
The complete dentures prepared in examples 1 to 3 and comparative examples 1 to 3 were tested according to the following method, and the test results are shown in table 1.
Bending property: the flexural modulus and flexural modulus of the curved bride of the complete denture base were tested according to GB/T9341-2008 "determination of Plastic flexural Properties".
Short-term bacteriostasis rate: the antibacterial rate of the complete denture base is detected according to a film close-fitting method in QB/T2591-2003 'antibacterial plastic antibacterial performance test method and antibacterial effect'.
Long-term bacteriostasis rate: soaking the base of the complete denture in artificial saliva, and standing at a constant temperature of 36-38 deg.C for 180 days; and then the antibacterial rate of the complete denture base is detected by adopting a film close-fitting method in QB/T2591-2003 'antibacterial plastic antibacterial performance test method and antibacterial effect'.
Feeling of use: 100 elderly persons 65-85 years old who need to wear complete dentures were selected as volunteers, all of whom were first wearers, and the feeling of use of complete dentures was evaluated according to the following criteria, a: no obvious sense of vomiting and reduced oral odor, B: has obvious sense of vomiting and no obvious change of peculiar smell in the oral cavity, and the proportion of the people with A is counted and evaluated.
TABLE 1
As can be seen from the data in Table 1, the complete denture prepared by the invention has excellent antibacterial effect and bending property, has good long-term antibacterial effect and good use feeling, and can relieve the nausea and vomiting feeling and the peculiar smell of the oral cavity of the old people who wear the complete denture for the first time.
The raw material of the base of comparative example 1 contained no natural antimicrobial agent; compared with the example 1, the short-term antibacterial rate of the comparative example 1 is obviously reduced, and the long-term antibacterial rate is slightly reduced, which shows that the antibacterial performance of the substrate can be improved by adding the natural antibacterial agent; the feeling of use of comparative example 1 was significantly reduced compared to example 1, indicating that the addition of natural antibacterial agents can significantly alleviate the feeling of nausea and vomiting and improve the oral malodor.
The silver-loaded silica in the starting material for the substrate of comparative example 2 was selected from the group prepared in preparation example 4, and contained no titanium dioxide and no zirconium dioxide in step (r) of the preparation process; compared with example 1, the short-term and long-term bacteriostatic rates of comparative example 2 are obviously reduced, which shows that the antibacterial effect of the silver-loaded silicon dioxide can be obviously improved by adding the titanium dioxide and the zirconium dioxide in the step I.
The silver-loaded silica in the raw material of the substrate of comparative example 3 was selected from those prepared in preparation example 5, and the silica was not subjected to the calcination treatment of step (i) in the preparation process; compared with example 1, the short-term and long-term bacteriostatic rates of comparative example 3 are obviously reduced, which shows that the antibacterial effect of the silver-loaded silica can be obviously improved after the calcination treatment in the step I.
The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.
Claims (7)
1. An antibacterial complete denture, which comprises an artificial tooth and an abutment, and is characterized in that: the base comprises the following components in parts by weight: 70-80 parts of denture powder, 30-40 parts of denture water, 2-3 parts of silicon toughener, 4-8 parts of silver-loaded silicon dioxide, 2-4 parts of natural antibacterial agent and 1-2 parts of nano titanium dioxide;
the silver-loaded silicon dioxide is prepared by the following method:
the preparation method comprises the following steps: taking 20-30 parts of silicon dioxide, 1-2 parts of titanium dioxide and 0.6-1 part of zirconium dioxide, grinding the silicon dioxide, calcining the silicon dioxide, the titanium dioxide and the zirconium dioxide at the temperature of 900-950 ℃, and cooling the silicon dioxide, the titanium dioxide and the zirconium dioxide to obtain a calcined material;
secondly, 0.2-0.3 part of silver nitrate powder is taken, 30 parts of water is added into the silver nitrate powder, and the mixture is uniformly stirred to obtain silver nitrate solution; adding 2-4 parts of calcined material into silver nitrate solution, and stirring at 20-30 deg.C for 10-20min to obtain mixed solution;
③ adding 0.2 to 0.4 portion of glucose and 1 to 2 portions of 10 weight percent aqueous solution of sodium hydroxide into the mixed solution, stirring for 10 to 20min, and obtaining silver-carrying silicon dioxide after suction filtration, washing and drying;
the natural antibacterial agent is prepared by mixing a reed rhizome extract, an eucommia ulmoides leaf extract and tea polyphenol in a weight ratio of 3:1: 1.
2. An antibacterial full denture according to claim 1, wherein: the drying temperature in the third step is 80-90 ℃, and the drying time is 6-8 h.
3. An antibacterial full denture according to claim 1, wherein: the silicon toughening agent polymethyl methacrylate-organic siloxane-acrylate core-shell copolymer.
4. An antibacterial full denture according to claim 1, wherein: the denture powder comprises the following components in parts by weight: 90-100 parts of polymethyl methacrylate and 1-2 parts of benzoyl peroxide initiator.
5. An antibacterial full denture according to claim 1, wherein: the denture water comprises the following components in parts by weight: 80-90 parts of methyl methacrylate, 0.3-0.5 part of accelerator and 0.6-0.32 part of UV-3200.4.
6. An antibacterial full denture according to claim 5, wherein: the accelerant is sodium p-toluenesulfinate.
7. A method of manufacturing an antibacterial full denture according to claim 1, wherein: the method comprises the following steps:
(1) preparing denture powder: taking 90-100 parts of polymethyl methacrylate and 1-2 parts of benzoyl peroxide initiator by weight parts, and uniformly stirring to obtain denture powder;
(2) preparing denture base water: taking 80-90 parts of methyl methacrylate, 0.3-0.5 part of accelerant and 0.6-0.3 part of UV-3200.4, and uniformly stirring to obtain denture fixing water;
(3) preparation of a base: uniformly stirring 70-80 parts of denture powder, 2-3 parts of silicon toughener, 4-8 parts of silver-loaded silicon dioxide, 6-8 parts of nano titanium dioxide and 2-4 parts of natural antibacterial agent to obtain a mixture, adding 30-40 parts of denture water into the mixture, stirring for 20min, and placing the mixture into a mold after the mixture is agglomerated; then placing the mould at the temperature of 70-75 ℃, and heating in a constant-temperature water bath for 90-120 min; heating to 100 deg.C, and heating at constant temperature for 40-60min to obtain cured base;
(4) preparing complete dentures: and mounting the artificial teeth on the base to obtain the complete denture.
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| CN110974461B (en) * | 2019-12-14 | 2021-05-11 | 深圳市爱科赢自动化技术有限公司 | Integrated complete denture digital manufacturing system and method |
| CN112063109B (en) * | 2020-09-11 | 2023-01-17 | 石家庄元鼎新材料有限公司 | Nano zinc oxide/artemisia yellow-wormwood volatile oil/epoxy resin high-performance antibacterial material and preparation method thereof |
| CN113181061A (en) * | 2021-04-16 | 2021-07-30 | 杭州富阳久和医疗器械有限公司 | Tough-reinforced antibacterial denture base and preparation method thereof |
| CN115414259B (en) * | 2022-09-30 | 2023-05-23 | 杭州拉瓦生物科技有限公司 | Customized type fixed denture and manufacturing method thereof |
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