CN110384182A - A kind of pure natural animal phagostimulant with antibacterial functions - Google Patents
A kind of pure natural animal phagostimulant with antibacterial functions Download PDFInfo
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- CN110384182A CN110384182A CN201910692446.8A CN201910692446A CN110384182A CN 110384182 A CN110384182 A CN 110384182A CN 201910692446 A CN201910692446 A CN 201910692446A CN 110384182 A CN110384182 A CN 110384182A
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- phagostimulant
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K40/00—Shaping or working-up of animal feeding-stuffs
Abstract
The invention belongs to food auxiliary material and food auxiliary material processing technique fields, and in particular to a kind of pure natural animal phagostimulant and preparation method thereof with antibacterial functions, abbreviation antibacterial are fragrant.The phagostimulant contains the raw materials such as Chinese anise, fennel seeds, cloves, monosodium glutamate, carrier.Phagostimulant of the invention can not only increase animal feed intake, and contain antibacterial substance, can improve animal intestinal tract, resistance building, improve animal feed intake and daily gain, moreover it is possible to reduce antioxidant and mould inhibitor usage amount in various degree, solve animal food calling and sterilization antioxidation in synthesis.
Description
Technical field
The invention belongs to food auxiliary material and food auxiliary material processing technique fields, and in particular to a kind of with the pure of antibacterial functions
Natural animal phagostimulant.
Background of invention
Feed intake is the key factor for guaranteeing breeding performonce fo animals and giving full play to, and is to influence butcher's beast body weight gains and feed
The principal element of utilization rate, and improve the important prerequisite of production efficiency.Therefore, as feed palatability is improved, increase raising
Application of the additive of the animal appetite ----phagostimulant in feed seems important.
Feed eating belt agent is also known as FEED FLAVOR or feedstuff flavouring agent, belongs to non-nutritive additive, is according to animal
One of the physiological characteristic and habit of different stages of growth, be added to feed to improve feed palatability and feed conversion rate
Additive.Wu Jing adds 0.6% and 1% delicate flavour phagostimulant in growing and fattening pigs diet, the results showed that adds 0.6% delicate flavour
Agent can significantly improve daily gain, and the production performance for adding 1% group is good not as good as 0.6 ‰ groups.Hao Zhimin etc. is studies have shown that addition
The feed-weight ratio of phagostimulant group is minimum, average daily gain it is extremely significant be higher than control group.A large number of studies show that flavouring agent can improve
The feed intake and daily gain of piglet.D.Torrallardona etc. divides weanling pig to control group and flavouring agent group, and (4 kinds of flavors are not
Same flavouring agent), the results show that production performance difference is not significant between 4 flavouring agent groups, and it is poor between flavouring agent and control group
It is different significant, illustrate that feedstuff flavouring agent not only improves feed intake and daily gain, further improves the price of deed.
Currently, the phagostimulant or flavouring agent in diet are chemical industry synthesis, what we should also regain consciousness is recognized, chemical industry synthesis
Phagostimulant while bringing glad tidings for our aquaculture, also along with certain harm, in order to safeguard public health, the world
Upper many countries, which have all formulated, uses standard in relation to flavoring agent, the stringent of phagostimulant；And current spice is concentrated mainly on food
Product and medicine are used and studys, and in terms of the animal food calling and research is rarely reported, and based on this, object of the present invention is to having
The phagostimulant of chemical industry synthesis in the pure natural phagostimulant substitution animal feed of antibacterial.
The mankind just widely apply spice far away from without literary records prehistory, archaeologist from pyramid wall as
Shape text and from the Bible of the Christian religion has been found that the ancestors of the mankind eat the traces of the important record of spice in life.
This illustrates that there is history very remote in China to the application of spice.
The spice for having found up to 500 kinds in the world at present, wherein there is 68 kinds to be included in China's national standard.It is fragrant pungent
Material or spice are can be used directly with tax perfume, blending, the fruit of seasoning function, seed, flower, root, stem, leaf, skin
Or the general name of the natural plants product such as complete stool.This some is widely used in medicine, religion, makeup, fragrant atmosphere or edible at present.
It is both domestic and external studies have shown that spice have stronger antioxygenic property；It is positive small brave equal (big with three kinds of Chinese anises
Red illiciumverum, Fructus Anisi Stellati, corner piece are octagonal) it is chemical component and antioxygenic property that raw material studies its volatile oil, the results showed that, eight
Angle volatile oil has stronger Scavenging ability, shows strong antioxygenic property.Lu etc. is anti-to 19 kinds of common spices
Oxidability, total phenol content and main phenolic compound are studied, and show that galangal has highest oxidation resistance, but
This kind of spices all have certain oxidation resistance, related with the total phenol content of raw material.Liu et al. uses the 5 of various concentration
Kind medicinal herbs and 17 kinds of spices, assess them to staphylococcus aureus, Escherichia coli, salmonella, comma bacillus, gemma bar
Bacterium inhibiting effect, the results showed that, spice is intended to inhibit gram-positive bacterium more than gramnegative bacterium.
21 century is a green century for pursuing herding safety and sustainable development, especially " nonreactive (antibiotic) "
It promotes, spice still belongs to blank, this patent in terms of livestock is as the pure natural phagostimulant research with antibacterial at present
Solve adding procedure on influences such as feed fragrance and flavors outside, provide scientific basis for high-efficiency antimicrobial, produce have increasing
Effect and " the natural antibacterial phagostimulant " of nonhazardous.In China, there is spice resource very rich, natural antibacterial phagostimulant has
Wide application prospect.
Summary of the invention
The purpose of the present invention is to provide a kind of animal phagostimulants, improve the feed intake and daily gain of animal.
The object of the invention is also to provide one kind to have antibacterial functions animal phagostimulant, can improve animal stomach, mention
The feed intake and daily gain of high animal.
The object of the invention is also to provide a kind of natural animal phagostimulants, antibiotic are not contained, to animal pair
It acts on small.
The object of the invention is also to provide a kind of natural animal phagostimulants, have the antioxygenic property of enhancing animal
Effect.
Above-mentioned purpose of the invention is realized by following technological means:
On the one hand, the present invention provides a kind of phagostimulant, the raw material containing following parts by weight:
As preferred embodiment, the phagostimulant contains the raw material of following parts by weight:
Embodiment more preferably, the animal phagostimulant contain the raw material of following parts by weight:
In an exemplary embodiment of the invention, the phagostimulant contains the raw material of following parts by weight:
In the present invention, the carrier can contain or not contain.It can be directly by luring from natural ingredient composition
Agent is eaten, or carrier can be further increased.
As preferred embodiment, the carrier is selected from silica.
As preferred embodiment, (impurity content is low, fineness requirement 95% through preferred specially treated for the silica
It is above to cross 80 mesh), all there is very high specific surface area and adsorption capacity is strong, mixed with other raw materials in preferential testing program
Even property is good.As preferred embodiment: moisture content is not higher than 1% in silica.As preferred embodiment, carrier
Middle silica impurities such as Pb, As, Cr, Cd, F etc. are far below sanitary standard requirement；Total number of molds etc. is far below health mark
Alignment request.
On the other hand, it the present invention also provides the preparation method of above-mentioned phagostimulant, the described method comprises the following steps:
1) coarse crushing: Chinese anise, cloves carry out coarse crushing respectively, and Chinese anise, cloves are because of oil-containing height, and shell is hard
Firmly；Hardly possible is broken.Pulverizer coarse crushing, sieve specification Φ 1.0-3.0 are stand-by after coarse powder respectively.
2) finely divided: Chinese anise and cloves and fennel seeds after coarse crushing carry out finely divided respectively；The choosing of sieve specification
With Φ 0.6-1.2；It is stand-by after crushing respectively；
3) be sieved: the it is 2) finely divided after raw material, be sieved respectively with rotor-vibrating screen, fineness requirement 85% crosses 40-100
Mesh, it is stand-by after sieving；
4) it mixes: first throwing 1/2 carrier in stainless steel vertical mixing mixing machine, then put into fennel seeds, cloves, octagonal fennel
Perfume (or spice) finally puts into remaining carrier.Wherein require mixing machine load factor for 60-85%, incorporation time 6-20 minutes；Mixing is equal
It is released after even and weighs, is packaged, labelled, storage.
In some embodiments,
In step 1)；Sieve specification selects Φ 1.2-2.0；
In step 2), sieve specification selects Φ 0.8-1.0；
In step 3), 50-80 mesh is crossed；
In step 4), mixing machine load factor be 65-80%, incorporation time 8-15 minutes.
In some embodiments,
In step 1)；Sieve specification selects Φ 1.2-1.5；
In step 2), sieve specification selects Φ 0.8；
In step 3), 60-70 mesh is crossed；
In step 4), mixing machine load factor be 70-75%, incorporation time 10-12 minutes；
In some embodiments,
In step 1)；Sieve specification selects Φ 1.2；
In step 2), sieve specification selects Φ 0.8；
In step 3), 60 meshes are crossed；
In step 4), mixing machine load factor be 70-75%, incorporation time 10 minutes.
On the other hand, the present invention also provides above-mentioned phagostimulants, are improving the application in animal feed intake.
On the other hand, the present invention also provides above-mentioned phagostimulants, are improving the application in animal daily gain.
On the other hand, the present invention also provides above-mentioned phagostimulants, the application in conditioning animal stomach.In some respects,
Antioxidant of the invention is by improving the antioxygenic property of animal come coordinating intestines and stomach.In some respects, of the invention anti-
Oxidant is to improve animal stomach by antibacterial or sterilization.
On the other hand, the present invention also provides above-mentioned phagostimulants, are improving the application in animal oxidation resistance.
On the other hand, the present invention also provides above-mentioned phagostimulants, the application in animal restraining and sterilizing bacteria.In the present invention, institute
The animal stated is selected from poultry or livestock or pet etc..
Further, the animal includes but is not limited to be selected from one of pig, ox, sheep, dog, horse, chicken, duck or goose.
In the preferred embodiment of the invention, the animal is selected from pig.
In a preferred embodiment of the invention, the animal is selected from piglet.
In a preferred embodiment of the invention, the animal is selected from weanling pig.Weanling pig is stimulated shadow by wean
It rings, the state such as feed appetite of various aspects is declined, and the Physiology and biochemistries state such as its soluble transferring receptor is caused to occur
Variation.And phagostimulant of the invention can just improve the feed appetite of weanling pig, improve its soluble transferring receptor, adjust
Stomach is managed, make piglet safety and steady tides over weaning period.
The present invention has beneficial effect below.
Core of the invention is meticulous pure natural raw material, and selection is natural, through vegetable raw material made of natural drying, is had
The substantially feature different from the flavouring agent of chemical industry synthesis.
A, pure natural；In process of production, all natural that any chemically synthesized substance maintains raw material is not added
Effectively at reaching Normal juice, original flavor, primary colors.
B, at fragrant uniform；According to each kind fragrance, scientific and reasonable proportion is taken, makes different flavor mouthfeel；Directly stir
It mixes uniformly, flavor is consistent.
C, it is able to extend the shelf-life of product；Natural flavor is in the production process by the ingredients such as aldehyde, ketone, alcohol in raw material
All retain, it is very that these substances itself, which have certain inhibiting effect to staphylococcus aureus, shigella dysenteriae, Escherichia coli etc.,
Natural antibacterial well, anti-oxidant and preservative.
D, cost is reduced；It is keeping product special flavour simultaneously, is reducing production cost.
Chinese anise, fennel seeds are the distinctive natural plants seed for having both seasoning and medical function in China, sweet in flavor, property
Temperature, have wind-dispelling qi-regulating, warming yang for dispelling cold, in stomach function regulating tune, regulating qi-flowing for relieving pain and other effects, and rich in there is the Huang with antioxidation
The compounds such as ketone, polyphenol, polysaccharide, this kind of compound can provide hydrogen atom, and hydrogen atom is easy former with the oxygen of oxide group (ROO.)
Son combines, so that lipid oxidation be blocked to react, plays anti-oxidant, antibacterial action.
Wherein, Guangxi is the maximum planting base of Chinese anise, and supply accounts for 80% or more of the whole nation or even generation.It is wide simultaneously
West-Association of South-east Asian Nations's Chinese medicine trade market be also south or even national " medicine is all ", various Chinese herbal medicines have to the greatest extent, and Guangdong is adjoined therewith,
So occupying the advantage of buying and transport.
Outstanding advantages of the invention are: this product retains material composition to the greatest extent, reaches Normal juice, original flavor, primary colors；It answers
Animal intestinal tract is not only improved with antibacterial incense products, is built up resistance, and improves animal feed intake and daily gain, moreover it is possible in various degree
Reduce antioxidant and mould inhibitor usage amount.Animal food calling and sterilization antioxidation are solved in synthesis.
Specific embodiment
Technical solution of the present invention is further illustrated below by way of specific embodiment, and specific embodiment does not represent to this hair
The limitation of bright protection scope.Other people according to the present invention theory made it is some it is nonessential modification and adjustment still fall within this hair
Bright protection scope.
Unless otherwise defined, all technical terms and scientific terms used in the present invention have and fields of the present invention
The identical meaning of the general understanding of those of ordinary skill.
1 phagostimulant of embodiment and preparation method thereof
Table 1
Above-mentioned phagostimulant the preparation method comprises the following steps:
Step 1: the coarse crushing of Chinese anise, cloves, Chinese anise, cloves are because of oil-containing height, and shell is hard；Hardly possible is broken.
Pulverizer coarse crushing, sieve specification Φ 1.0-3.0 are stand-by after coarse powder respectively.
Step 2: Chinese anise, cloves and fennel seeds it is finely divided；Sieve specification selects Φ 0.6-1.2；After crushing respectively
For use；
Step 3: sieving, the raw material after second step is finely divided are sieved with rotor-vibrating screen respectively, fineness requirement 85%
40-100 mesh is crossed, it is stand-by after sieving；
Step 4: weighing, according to the ratio of any phagostimulant of above-mentioned 1-4, precise.
Step 5: the load weighted each raw material of the 4th step is required to feed intake according to the rules: first throwing 1/2 carrier in stainless by mixing
In steel vertical mixing mixing machine, then fennel seeds, cloves, Chinese anise are put into, finally puts into remaining carrier.It is required that mixing machine fills
Load coefficient be 60-85%, incorporation time 6-20 minutes；It releases after mixing and weighs, is packaged, label, storage.
Embodiment 2
Test selection three way cross weanling pig 56 of 30 ages in days, is randomly divided into control group, test group, and every group 28,
Wherein test group adds phagostimulant of the invention (combination 3 in embodiment 1,500g/ tons), (does not add food calling within experimental period 30 days
Agent), remaining condition is identical.During test, hand fed is freely eaten, and free water, immune programme is according to pig farm conventional method
It carries out.Situations such as feed intake of observation and statistics piglet, Gain weight, the death rate and disease.
Test result such as table 2.
Table 2
The average daily gain that addition phagostimulant of the invention as the result is shown in table 2 can significantly improve pig (is promoted
7.35%), so that average daily gain improves.More significantly, phagostimulant of the invention has lower material ratio, energy
Aquaculture cost is enough reduced, the economic benefit of cultivation is improved.
Meanwhile in order to determine the optimum efficiency in formula range, a series of experiments is also carried out.This experiment is mainly observed young
The research of phagostimulating effect after pig wean, with the optimal formulation content of determination.Weanling pig 150 of test 30 ages in days of selection, with
Machine be divided into test group 1 (1 is combined in embodiment), test group 2 (combining 2 in embodiment 1), test group 3 (combining 3 in embodiment 1),
Test group 4 (combining 4 in embodiment 1), test group 5 (combining 5 in embodiment 1), every group of 3 repetitions, each repetition 10, addition
Amount is 500g/ tons, and experimental period 30 days, remaining condition was identical.During test, hand fed is freely eaten, and free water is exempted from
Epidemic disease program is carried out according to pig farm conventional method.The feelings such as feed intake, Gain weight, the death rate and the disease of observation and statistics piglet
Condition.
Test result such as table 3.
3 different formulations of table are to Growth Performance of Weaning Piglets Index Influence
Due to being influenced by weaning stress, piglet several days feed intakes and weight gain after wean is slow, adds of the invention
Phagostimulant can improve daily ingestion amount and average daily gain.More significantly, combination 2 and combination 3 in phagostimulant of the invention combination
Weight gain or material are better than other several groups of effects than upper.
4 different formulations of table influence weanling pig physiochemical indice
To antioxidant enzyme superoxide mutase (SOD), glutathione peroxidase in weanling pig physiochemical indice in table 4
Enzyme (GSH-PX), catalase (CAT) active analysis show the effect of test group 2 and 3 better than other test groups.Show this
The test combinations of invention not only have effects that food calling, and have antibacterial anti-inflammatory advantage.2 and 3 have preferably in invention example combination
Performance.
Embodiment 3
Test initial stage, inventor once screened thyme, vanilla, dried orange peel, Chinese anise, fennel seeds, cloves, monosodium glutamate, sucrose
Etc. plurality of raw materials be combined screening.It needs to consider numerous factors, such as raw material sources, component content, phagostimulating effect, crushes effect
Consideration such as fruit etc..
By different ratio test combinations more than 1 year, above-mentioned formula material and recipe ingredient ratio are finally screened, it can be preferable
Reach food calling and takes into account restraining and sterilizing bacteria effect.
Then effect is less desirable for remaining combination.Such as select vanilla, cloves, Chinese anise, monosodium glutamate and carrier combination, test
It is inferior to be shown in antibacterial anti-inflammatory aspect.
The following are the present invention to screen part combination and corresponding experimental result.
Three way cross weanling pig 56 of test 1 age in days of selection, are randomly divided into control group, test group 1 (in embodiment 1
Combination 3 in vanilla substitute cloves), test group 2 (in the combination 3 in embodiment 1 with thyme substitute cloves), test group 3
(combination 3 in embodiment 1), every group 14, the wherein combination addition of test group 1,2 and 3 phagostimulant (500g/ tons), control group is not
Addition；Experimental period 30 days, remaining condition was identical.During test, hand fed, be freely eaten, free water, immune programme according to
Pig farm conventional method carries out.Measure serum superoxide dismutases (SOD) activity, Serum glutathione peroxidase (GSH-
Px) the indexs such as activity, soluble transferring receptor (T-AOC), see Table 5 for details, table 6, table 7.
5 piglet serum activity of SOD (U/ml) of table
As shown in table 5, SOD vigor in 1 day, 7 days, 14 days and 28 days surveyed piglet serum of wean, test group is than control
Group increases.But test group 1 and test group 2. are better than with 3 result of test group
6 piglet GSH-Px in serum vigor (U/ml) of table
If table 6 can be seen that, piglet Serum glutathione peroxidase content is increased after wean, and maintains one
Fixed level.When weaning 28, GSH-Px content is higher than control group in test group, and test group 1 and 2 difference on effect of test group are not shown
It writes.3 effect of test group is better than test group 1 and test group 2.
7 piglet serum T-AOC vigor (U/ml) of table
If table 7 can be seen that, weanling pig soluble transferring receptor is on a declining curve after wean, especially under control group
It drops the most obvious, it is seen that by wean stimulus effects.The oxidation resistance of test group piglet is better than control group, 3 test groups
In, it is especially best with 3 effect of test group.
The test group it is found that feeding phagostimulant of the present invention is summarized, superoxide dismutase (SOD) activity in serum,
Serum glutathione peroxidase (GSH-px) activity, soluble transferring receptor (T-AOC) are superior to other test groups,
Enteron aisle anti-oxidative damage ability is strong.The phagostimulant that the present invention contains Chinese anise, fennel seeds, cloves and monosodium glutamate not only has raising
The effect of feed intake, and anti-oxidant, restraining and sterilizing bacteria effect can be taken into account.The prior art, vanilla, thyme are commonly used to as food
Flavoring agent, also someone uses vanilla, thyme as phagostimulant or antibacterial agent, but it has been investigated that the two and remaining of the invention
Component cooperation, antioxidant effect are not so good as combination of the invention.
Claims (10)
1. a kind of phagostimulant, which is characterized in that the raw material containing following parts by weight:
2. phagostimulant according to claim 1, which is characterized in that the raw material containing following parts by weight:
3. phagostimulant according to claim 1, which is characterized in that the raw material containing following parts by weight:
4. phagostimulant according to claim 1, which is characterized in that the raw material containing following parts by weight:
5. -4 any phagostimulant according to claim 1, which is characterized in that
The carrier is selected from silica；
Preferably, moisture content is not higher than 1% in silica；
Preferably, the fineness of silica is higher than 95%.
6. the preparation method of any phagostimulant of claim 1-5, which comprises the following steps:
1) coarse crushing: carrying out coarse crushing for Chinese anise, Ground Cloves respectively, sieve specification Φ 1.0-3.0, for use；
2) finely divided: Chinese anise, the cloves in fennel seeds and step 1) carry out finely divided respectively；Sieve specification selects Φ
0.6-1.2, for use；
3) be sieved: the raw material after respectively will be finely divided crosses 40-100 mesh, for use；
4) it mixes: first throwing 1/2 carrier, then put into fennel seeds, cloves, Chinese anise, finally put into remaining carrier, mix；It is excellent
Selection of land, mixing machine load factor be 60-85%, incorporation time 6-20 minutes；
Preferably,
In step 1)；Sieve specification Φ 1.2-2.0；
In step 2), sieve specification selects Φ 0.8-1.0；
In step 3), 50-80 mesh is crossed；
In step 4), mixing machine load factor be 65-80%, incorporation time 8-15 minutes；
Preferably,
In step 1)；Sieve specification Φ 1.2-1.5；
In step 2), sieve specification selects Φ 0.8；
In step 3), 60-70 mesh is crossed；
In step 4), mixing machine load factor be 70-75%, incorporation time 10-12 minutes；
Preferably,
In step 1)；Sieve specification Φ 1.2；
In step 2), sieve specification selects Φ 0.8；
In step 3), 60 meshes are crossed；
In step 4), mixing machine load factor be 70-75%, incorporation time 10 minutes.
7. any phagostimulant of claim 1-5, is improving the application in animal feed intake.
8. any phagostimulant of claim 1-5, is improving the application in animal daily gain.
9. any phagostimulant of claim 1-5, the application in conditioning animal stomach, or
Improving the application in animal oxidation resistance；Or the application in animal restraining and sterilizing bacteria.
10. according to any application of claim 7-9, which is characterized in that the animal be selected from pig, ox, sheep, dog, horse,
One of chicken, duck or goose；
Preferably, the animal is selected from pig；
Preferably, the animal is selected from piglet；
Preferably, the animal is selected from weanling pig.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112617043A (en) * | 2020-06-09 | 2021-04-09 | 南京泛成生物科技有限公司 | Natural animal feed additive and preparation method thereof |
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