CN110352860A - A kind of tail like chain mouse cage - Google Patents

A kind of tail like chain mouse cage Download PDF

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Publication number
CN110352860A
CN110352860A CN201910691166.5A CN201910691166A CN110352860A CN 110352860 A CN110352860 A CN 110352860A CN 201910691166 A CN201910691166 A CN 201910691166A CN 110352860 A CN110352860 A CN 110352860A
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CN
China
Prior art keywords
mouse
tail
mouse cage
sliding
bandage
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Granted
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CN201910691166.5A
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Chinese (zh)
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CN110352860B (en
Inventor
许学猛
陈国茜
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Guangdong Second Traditional Chinese Medicine Hospital (guangdong Research Institute Of Traditional Chinese Medicine Manufacturing Technology)
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Guangdong Second Traditional Chinese Medicine Hospital (guangdong Research Institute Of Traditional Chinese Medicine Manufacturing Technology)
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Priority to CN201910691166.5A priority Critical patent/CN110352860B/en
Publication of CN110352860A publication Critical patent/CN110352860A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03Housing for domestic or laboratory animals
    • A01K1/031Cages for laboratory animals; Cages for measuring metabolism of animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/035Devices for use in keeping domestic animals, e.g. fittings in housings or dog beds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D3/00Appliances for supporting or fettering animals for operative purposes

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  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Catching Or Destruction (AREA)

Abstract

The invention discloses a kind of tail like chain mouse cages, include: at least one mouse cage unit, mouse is defined in mouse cage unit and hangs chamber, mouse hangs intracavitary sliding and is provided with partition, mouse is hung chamber and is separated into two mouse by partition hangs space, and partition sliding can adjust the size that two mouse hang space;Suspension apparatus is mounted on above each suspention space, suspension apparatus includes: sliding cross bar, suspention spring, suspension ring and Bang Wei mechanism, sliding cross bar is slidably arranged in the top that mouse hangs space, suspension ring is set on sliding cross bar, one end of suspention spring is connect with suspension ring, and the other end for suspending spring in midair is connect with Bang Wei mechanism;The case where can suspending the tail of experimental mouse in midair, and to rat-tail fixation, hurtless measure by Bang Wei mechanism, not will cause rat-tail damage, rat-tail detachment or rat-tail ischemic necrosis generation, ensure that sample size, guarantees the accuracy of experimental result.

Description

A kind of tail like chain mouse cage
Technical field
The present invention relates to use for laboratory simulators, more particularly to a kind of tail like chain mouse cage.
Background technique
Muscular atrophy of disuse is clinically common complication, and hypokinesis, the weightless, braking of aviation etc. can cause obvious Muscular atrophy of disuse, influence the motor function of human body.Therefore, how to prevent and treat muscular atrophy of disuse seems especially heavy It wants.Amyotrophia caused by tail like chain mouse is common animal model mode, facilitates the research of amyotrophia.
Presently, there are tail like chain mouse cage have many defects:
1, existing experiment tail suspension method is mainly using rope ligatures, adhesive tape is fixed or clip is fixed.But due to Rat-tail is in pyramid type, and root is thick, and end is thin, and when suspention needs for suspension rope to be fixed on the end of rat-tail.Experimental mouse meeting when hanging upside down It swings and struggles, ligatured using rope or directly suspend rat-tail in midair with typical clamp and easily fall off.Furthermore it when the weight of mouse is larger, hangs Rat-tail is hung also easily to fall off.And if rope ligation tension or clip excessively clamp, it will lead to rat-tail damage, rat-tail detachment Or rat-tail ischemic necrosis, it cannot continue to test, influence experimental result.
2, it is fixed for filling the mouse cage size of experimental mouse, and the size of experimental mouse is not unified, and when with experiment Between growth, also president's experimental mouse fills out greatly, and the mouse cage of fixed size will affect experiment effect, reduces conventional efficient, increases real Test cost.
Summary of the invention
The purpose of the present invention is overcoming the deficiencies of the prior art and provide a kind of tail like chain mouse cage, in tail suspension process Middle rat-tail is not easily to fall off, and does not easily cause rat-tail ischemic necrosis, can improve conventional efficient.
To achieve the goals above, the present invention provides a kind of tail like chain mouse cage, comprising: at least one mouse cage unit, it is described Mouse is defined in mouse cage unit and hangs chamber, and the mouse hangs intracavitary sliding and is provided with partition, and the mouse is hung chamber and is separated by the partition Two mouse hang space, and the partition sliding can adjust the size that two mouse hang space;
Suspension apparatus is mounted on above each suspention space, the suspension apparatus includes: sliding cross bar, suspention bullet Spring, suspension ring and Bang Wei mechanism, the sliding cross bar are slidably arranged in the top that the mouse hangs space, and the suspension ring is arranged On the sliding cross bar, one end of the suspention spring is connect with the suspension ring, the other end of the suspention spring and institute The connection of Shu Bang tail mechanism;
The Bang Wei mechanism includes the inflatable article of air pump, gas tube, bandage and rubber material, is equipped with and fills in the inflatable article Air cavity, the inflatable article are set to the inside of the bandage, and the air pump is connected to by the gas tube with the inflatable chamber, institute The both ends for stating bandage are respectively equipped with mutually matched velcro;
The Bang Wei mechanism further includes control assembly, and the control assembly includes pressure sensor and controller, the pressure Force snesor is arranged on the medial surface of the bandage, and the air pump is electrically connected with the controller;The pressure sensor inspection The pressure that tightens of the bandage medial surface is surveyed, and pressure signal is exported to the controller, the controller is according to the pressure Force signal adjusts the output gas flow size of the air pump.
Preferably, the bottom that each mouse hangs space is provided with water fountain and crib.
Preferably, photographic device is installed above the mouse cage unit.
Preferably, the sliding cross bar is arranged in parallel with the partition, the top of the side wall of the mouse cage unit It is provided with first sliding groove, the both ends of the sliding cross bar are provided with the first sliding block that can be slided in the first sliding groove.
Preferably, the bottom of the mouse cage unit is provided with second sliding slot, and the bottom of the partition is provided with can The second sliding block slided in the second sliding slot.
Preferably, the bottom of the mouse cage unit is hollow out floor.
Preferably, four side walls of the mouse cage unit are made of transparent organic glass.
Preferably, the internal layer of the bandage is made of anti-skidding cloth material.
Preferably, the height of the mouse cage unit be 40~60cm, length be 40~60cm, width be 20~ 30cm。
Preferably, the height of the mouse cage unit is 60cm, length 60cm, width 30cm.
Compared with prior art, the beneficial effects of the present invention are:
The tail like chain mouse cage of the embodiment of the present invention, mouse hang intracavitary sliding and are provided with partition, and mouse is hung chamber and is separated into two by partition A mouse hangs space, and partition sliding can adjust the size that two mouse hang space, flexible and convenient to use, reduce experimental facilities at This.
Suspension apparatus is installed above mouse cage unit, experimental mouse suspention can be got up by the tail of experimental mouse, be hanged Device for hoisting includes: sliding cross bar, suspention spring, suspension ring and Bang Wei mechanism, and sliding cross bar is slidably arranged in suspention cage top portion, Suspension ring is set on sliding cross bar, and the one end for suspending spring in midair is connect with suspension ring, and suspention spring can extend therewith, so as to It prevents from experimental mouse from swinging rat-tail when struggling to fall off, the other end for suspending spring in midair is connect with Bang Wei mechanism, and experimental mouse can be looked for freely Food, drinking-water and activity, it is unrestricted;Bang Wei mechanism includes the inflatable article of air pump, gas tube, bandage and rubber material, inflatable article Interior to be equipped with inflatable chamber, inflatable article is set to the inside of bandage, and air pump is connected to by gas tube with inflatable chamber, the both ends difference of bandage Equipped with mutually matched velcro, the tail of experimental mouse is placed in bandage medial surface, bandage is crimped, by bandage both ends The tail of velcro bonding, experimental mouse is rolled up by bandage, by air pump to inflation interacvity air-filling, by bandage to the pressure of rat-tail Power fastens the tail of experimental mouse, is hung bandage by suspention spring, so that it may and it is safe and efficient nondestructively to suspend experimental mouse in midair, And to rat-tail fixation, hurtless measure, the case where not will cause rat-tail damage, rat-tail detachment or rat-tail ischemic necrosis generation, It ensure that sample size, guarantee the accuracy of experimental result.
Further, the Bang Wei mechanism of the embodiment of the present invention further includes control assembly, and control assembly includes pressure sensor And controller, pressure sensor are arranged on the medial surface of bandage, air pump is electrically connected with the controller;Pressure sensor detects bandage Medial surface tightens pressure, and pressure signal is exported to controller, and controller adjusts the output gas of air pump according to pressure signal Size is flowed, realizes and automatically controls rat-tail fastening, rat-tail will not fall off during suspention, improve conventional efficient.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of tail like chain mouse cage in the embodiment of the present invention;
Fig. 2 is the structural schematic diagram of Zhong Bang tail of embodiment of the present invention mechanism;
Fig. 3 is control assembly signal connection schematic diagram in the embodiment of the present invention.
In figure, 1, mouse cage unit;11, mouse hangs space;2, suspension apparatus;21, cross bar is slided;22, spring is suspended in midair;23, it hangs Hanging ring;24, Bang Wei mechanism;241, air pump;242, gas tube;243, bandage;3, pressure sensor;4, controller;5, partition;6, Water fountain;7, crib;8, photographic device.
Specific embodiment
With reference to the accompanying drawings and examples, specific embodiments of the present invention will be described in further detail.Implement below Example is not intended to limit the scope of the invention for illustrating the present invention.
In the description of the present invention, it is to be understood that, term " on ", "lower", "left", "right", "top", "bottom", " preceding ", The orientation or positional relationship of instructions such as " rear " is to be based on the orientation or positional relationship shown in the drawings, and is merely for convenience of describing this hair Bright and simplified description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with specific orientation Construction and operation, therefore be not considered as limiting the invention.It should be understood that in the present invention using term " first ", " second " etc. describes various information, but these information should not necessarily be limited by these terms, these terms are only used to will be same type of Information is distinguished from each other out.For example, without departing from the present invention, " first " information can also be referred to as " second " letter Breath, similar, " second " information can also be referred to as " first " information.
As shown in Figure 1 to Figure 3, a kind of tail like chain mouse cage, comprising: mouse cage unit 1 defines mouse in mouse cage unit 1 and hangs chamber, Mouse hangs intracavitary sliding and is provided with partition 5, and the bottom of mouse cage unit 1 is provided with second sliding slot, and the bottom of partition 5 is provided with can be the The second sliding block slided in two sliding slots, mouse is hung chamber and is separated into two mouse by partition 5 hangs space 11, and the sliding of partition 5 can adjust two A mouse hangs the size in space 11, flexible and convenient to use, reduces experimental facilities cost.
Suspension apparatus 2 is mounted on above each suspention space, suspension apparatus 2 includes: sliding cross bar 21, suspention spring 22, suspension ring 23 and Bang Wei mechanism 24, sliding cross bar 21 are slidably arranged in the top that mouse hangs space 11, sliding cross bar 21 with every Plate 5 is arranged in parallel, and is provided with first sliding groove at the top of the side wall of mouse cage unit 1, and the both ends of sliding cross bar 21 are provided with can be the The first sliding block slided in one sliding slot, suspension ring 23 are set on sliding cross bar 21, suspend one end and the suspension ring 23 of spring 22 in midair The other end of connection, suspention spring 22 is connect with Bang Wei mechanism 24;Suspending spring 22 in midair has elasticity, struggles when experimental mouse is swung When, suspention spring 22 can extend therewith, and rat-tail falls off when struggling so as to prevent experimental mouse from swinging, and experimental mouse can be looked for freely Food, drinking-water and activity, it is unrestricted.
Bang Wei mechanism 24 includes the inflatable article of air pump 241, gas tube 242, bandage 243 and rubber material, is set in inflatable article There is inflatable chamber, inflatable article is set to the inside of bandage 243, and air pump 241 is connected to by gas tube 242 with inflatable chamber, bandage 243 Both ends are respectively equipped with mutually matched velcro;The tail of experimental mouse is placed in the medial surface of bandage 243, bandage 243 is carried out The velcro at 243 both ends of bandage is bonded by curling, and the tail of experimental mouse is lived by bandage volume 243, by air pump 241 to inflation Interacvity air-filling is fastened the tail of experimental mouse by pressure of the bandage 243 to rat-tail, is hanged bandage 243 by suspention spring 22 It hangs, so that it may fast nondestructively suspend experimental mouse in midair, and rat-tail fixation, the internal layer of bandage 243 uses anti-skidding cloth material It is made, is conducive to increasing friction force, rat-tail is not easily to fall off, and bandage 243 and the contact area of rat-tail are larger, not will cause rat-tail damage The case where wound, rat-tail detachment or rat-tail ischemic necrosis, occurs, and ensure that sample size, guarantees the accuracy of experimental result.
Bang Wei mechanism 24 further includes control assembly, and control assembly includes pressure sensor 3 and controller 4, pressure sensor 3 It is arranged on the medial surface of bandage 243, air pump 241 is electrically connected with controller 4;Pressure sensor 3 detects 243 medial surface of bandage Pressure is tightened, and pressure signal is exported to controller 4, controller 4 is big according to the output gas flow that pressure signal adjusts air pump 241 It is small.When the pressure that pressure sensor 3 detects reaches the lower limit value of setting, pressure sensor 3 sends a letter to controller 4 Number, controller 4 gives one signal of transmission of air pump 241 after receiving and analyzing, and air pump 241 is filled by gas tube 242 into inflatable chamber Gas, bandage 243 increases the pressure of rat-tail, and when the pressure that pressure sensor 3 detects reaches the upper limit value of setting, pressure is passed Sensor 3 sends a signal to controller 4, and controller 4 gives one electric signal of transmission of air pump 241, air pump 241 after receiving and analyzing Stop inflation, automatically control rat-tail fastening to realize, rat-tail will not fall off during suspention, improve conventional efficient.
The bottom that each mouse hangs space 11 is provided with water fountain 6 and crib 7, and experimental mouse is facilitated to drink water and feed.
The top of mouse cage unit 1 is equipped with photographic device 8, for obtaining experimental mouse simulated weightlessness tail portion in mouse cage unit 1 Long-term, dynamic, continuous, real-time spontaneous activity image information when suspention experiment.
The bottom of mouse cage unit 1 is hollow out floor, and the excreta of experimental mouse is facilitated to leak down.
Four side walls of mouse cage unit 1 are made of transparent organic glass, convenient for the state of animal in observation tail device for hoisting.
The height of mouse cage unit 1 is 60cm, length 60cm, width 30cm, reasonable in design.
The above is only a preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For member, without departing from the technical principles of the invention, several improvement and replacement can also be made, these are improved and replacement Also it should be regarded as protection scope of the present invention.

Claims (10)

1. a kind of tail like chain mouse cage characterized by comprising at least one mouse cage unit defines mouse in the mouse cage unit Hang chamber, the mouse hangs intracavitary sliding and is provided with partition, and the mouse is hung chamber and is separated into two mouse by the partition hangs space, it is described every Plate sliding can adjust the size that two mouse hang space;
Be mounted on suspension apparatus above each suspention space, the suspension apparatus include: sliding cross bar, suspention spring, Suspension ring and Bang Wei mechanism, the sliding cross bar are slidably arranged in the top that the mouse hangs space, and the suspension ring is set in On the sliding cross bar, it is described suspention spring one end connect with the suspension ring, it is described suspend in midair spring the other end with it is described The connection of Bang Wei mechanism;
The Bang Wei mechanism includes the inflatable article of air pump, gas tube, bandage and rubber material, is equipped with inflation in the inflatable article Chamber, the inflatable article are set to the inside of the bandage, and the air pump is connected to by the gas tube with the inflatable chamber, described The both ends of bandage are respectively equipped with mutually matched velcro;
The Bang Wei mechanism further includes control assembly, and the control assembly includes pressure sensor and controller, and the pressure passes Sensor is arranged on the medial surface of the bandage, and the air pump is electrically connected with the controller;The pressure sensor detects institute The pressure that tightens of bandage medial surface is stated, and pressure signal is exported to the controller, the controller is believed according to the pressure Number adjust the output gas flow size of the air pump.
2. tail like chain mouse cage as described in claim 1, which is characterized in that the bottom that each mouse hangs space is provided with drinking-water Device and crib.
3. tail like chain mouse cage as described in claim 1, which is characterized in that be equipped with camera shooting dress above the mouse cage unit It sets.
4. tail like chain mouse cage as described in claim 1, which is characterized in that the sliding cross bar is arranged in parallel with the partition, First sliding groove is provided at the top of the side wall of the mouse cage unit, the both ends of the sliding cross bar are provided with can be sliding described first The first sliding block slided in slot.
5. tail like chain mouse cage as described in claim 1, which is characterized in that it is sliding that the bottom of the mouse cage unit is provided with second Slot, the bottom of the partition are provided with the second sliding block that can be slided in the second sliding slot.
6. tail like chain mouse cage as described in claim 1, which is characterized in that the bottom of the mouse cage unit is hollow out floor.
7. tail like chain mouse cage as described in claim 1, which is characterized in that four side walls of the mouse cage unit are transparent organic Glass is made.
8. tail like chain mouse cage as described in claim 1, which is characterized in that the internal layer of the bandage uses anti-skidding cloth material system At.
9. such as tail like chain mouse cage of any of claims 1-8, which is characterized in that the height of the mouse cage unit is 40 ~60cm, length are 40~60cm, and width is 20~30cm.
10. tail like chain mouse cage as claimed in claim 9, which is characterized in that the height of the mouse cage unit is 60cm, and length is 60cm, width 30cm.
CN201910691166.5A 2019-07-29 2019-07-29 Tail suspension squirrel cage Active CN110352860B (en)

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Application Number Priority Date Filing Date Title
CN201910691166.5A CN110352860B (en) 2019-07-29 2019-07-29 Tail suspension squirrel cage

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CN110352860A true CN110352860A (en) 2019-10-22
CN110352860B CN110352860B (en) 2021-09-14

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112400718A (en) * 2020-11-05 2021-02-26 天津大学 Screw-nut type buckle structure and method for simulating weightless rat tail suspension

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200413731A (en) * 2003-01-17 2004-08-01 Taipei Veterans General Hospital Tail suspension test device
US20050076847A1 (en) * 2003-10-10 2005-04-14 Anthony Denietolis Motor assisted swivel
CN201905126U (en) * 2010-12-20 2011-07-27 中国人民解放军总医院 Simulation weightless tail-suspension device
CN203120680U (en) * 2013-03-11 2013-08-14 辽宁中医药大学 Unloading weightlessness simulation device for hind legs of laboratory mice
CN103283623A (en) * 2013-06-08 2013-09-11 中国航天员科研训练中心 Device monitoring suspension of stimulated animal weightlessness tails in real time
CN203692144U (en) * 2014-01-24 2014-07-09 山西医科大学 Rat tail suspension cage
CN108174791A (en) * 2018-03-12 2018-06-19 苏州新区枫桥净化设备有限公司 A kind of multipurpose pet cage of Space adjustment
CN208258707U (en) * 2018-03-20 2018-12-21 北京慧荣和科技有限公司 A kind of mouse cage for systemic exposure chamber
CN109512542A (en) * 2018-10-29 2019-03-26 江汉大学 A kind of suspension apparatus and method

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200413731A (en) * 2003-01-17 2004-08-01 Taipei Veterans General Hospital Tail suspension test device
US20050076847A1 (en) * 2003-10-10 2005-04-14 Anthony Denietolis Motor assisted swivel
CN201905126U (en) * 2010-12-20 2011-07-27 中国人民解放军总医院 Simulation weightless tail-suspension device
CN203120680U (en) * 2013-03-11 2013-08-14 辽宁中医药大学 Unloading weightlessness simulation device for hind legs of laboratory mice
CN103283623A (en) * 2013-06-08 2013-09-11 中国航天员科研训练中心 Device monitoring suspension of stimulated animal weightlessness tails in real time
CN203692144U (en) * 2014-01-24 2014-07-09 山西医科大学 Rat tail suspension cage
CN108174791A (en) * 2018-03-12 2018-06-19 苏州新区枫桥净化设备有限公司 A kind of multipurpose pet cage of Space adjustment
CN208258707U (en) * 2018-03-20 2018-12-21 北京慧荣和科技有限公司 A kind of mouse cage for systemic exposure chamber
CN109512542A (en) * 2018-10-29 2019-03-26 江汉大学 A kind of suspension apparatus and method

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112400718A (en) * 2020-11-05 2021-02-26 天津大学 Screw-nut type buckle structure and method for simulating weightless rat tail suspension
CN112400718B (en) * 2020-11-05 2021-09-17 天津大学 Buckle structure and method for simulating weightless rat tail suspension

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