CN103283623A - Device monitoring suspension of stimulated animal weightlessness tails in real time - Google Patents

Device monitoring suspension of stimulated animal weightlessness tails in real time Download PDF

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Publication number
CN103283623A
CN103283623A CN2013102289492A CN201310228949A CN103283623A CN 103283623 A CN103283623 A CN 103283623A CN 2013102289492 A CN2013102289492 A CN 2013102289492A CN 201310228949 A CN201310228949 A CN 201310228949A CN 103283623 A CN103283623 A CN 103283623A
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China
Prior art keywords
animal
comes
tail
afterbody
suspention
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CN2013102289492A
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Chinese (zh)
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CN103283623B (en
Inventor
陈善广
刘新民
王琼
李莹辉
李海清
董丽
李由
曲丽娜
张永亮
陈晓萍
王春慧
杨思进
何涛
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BEIJING XINHAIHUAYI TECHNOLOGY Co Ltd
LUZHOU MEDICAL COLLEGE
China Astronaut Research and Training Center
Original Assignee
BEIJING XINHAIHUAYI TECHNOLOGY Co Ltd
LUZHOU MEDICAL COLLEGE
China Astronaut Research and Training Center
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Priority to CN201310228949.2A priority Critical patent/CN103283623B/en
Publication of CN103283623A publication Critical patent/CN103283623A/en
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Abstract

The invention provides a device monitoring suspension of stimulated animal weightlessness tails in real time. The device comprises at least one box body unit, the box body unit comprises at least one tail suspending cage, a camera shooting device and a computer system, wherein the tail suspending cage is arranged in the box body unit and used for providing space for a suspension test on the animal tails; the camera shooting device is arranged above the box body unit and used for acquiring image information of the suspension test on the animal tails in the box body unit, a suspending device is arranged above each tail suspending cage and used for being connected with the animal tails, each tail suspending cage is provided with a falling-off detecting device which is used for detecting whether the animal tails fall off in the suspension test on the animal tails, and the falling-off detecting device gives out an alarming signal when the animal tails are detected to fall off; the computer system is used for receiving the image information transmitted by the camera shooting device and the alarming signal transmitted by the falling-off detecting device and transmitting the alarming signal to an appointed tester. The device can accurately acquire the state of autonomic action of the suspended animal tails and automatically give an alarm when the animal tails fall off.

Description

A kind of animal simulated weightlessness afterbody suspends real-time device for monitoring in midair
Technical field
The invention belongs to zoopery equipment, be specifically related to a kind of animal simulated weightlessness afterbody and suspend real-time device for monitoring in midair.
Background technology
Aerospace medicine research needs suitable animal model, and classical simulated weightlessness rat model is that the scientist Morey-Holton of US National Aeronautics and Space Administration (NASA) proposes " afterbody suspention rat model ".The autonomic activities situation of animal when real-time monitoring, analysis and the processing of animal afterbody suspention autonomic activities refers to real-time monitoring, record and analysis afterbody suspention (forelimb lands, and hind leg is liftoff, and health and the horizontal plane of animal are angled).
Yet there is following problem in animal simulated weightlessness afterbody suspention at present: one, still can not obtain independent activity of animals situation under the animal afterbody suspended state comprehensively; Two, animal afterbody suspention situation about coming off happens occasionally, if can not in time find to handle, can cause this sample to lose authenticity and reliability.
Summary of the invention
In order to solve the problems of the technologies described above, the purpose of this invention is to provide a kind of animal simulated weightlessness afterbody and suspend real-time device for monitoring in midair, this device can accurately be caught the autonomic activities state of animal afterbody suspention and be realized reporting to the police automatically when the animal afterbody comes off.
The invention provides a kind of animal simulated weightlessness afterbody and suspend real-time device for monitoring in midair, device comprises: at least one box unit, each box unit comprises at least one tail cage, and the tail cage is arranged in the box unit, is used for providing the space of animal afterbody suspention experiment; The top of each box unit is equipped with camera head, the image information when being used for obtaining box unit animal afterbody suspention experiment; The top of each tail cage is equipped with suspension apparatus, is used for being connected with the animal afterbody; Whether each tail cage top is equipped with the checkout gear that comes off, be used for detecting the suspention of animal afterbody and coming off when animal afterbody suspention experiment, and when detecting the animal afterbody and come off, send alarm signal; And computer system, be used for receiving the image information of camera head transmission and the alarm signal that the described checkout gear that comes off sends, and alarm signal sent to the experimenter of appointment.
Alternatively, this device also comprises: at least one light emitting diode and being used for to the light emitting diode power supply, and the power-supply system of control light source, wherein light emitting diode is arranged on the cage wall of tail cage.
Alternatively, this light emitting diode is infrarede emitting diode.
Alternatively, this device also comprises: Infrared Lens, be arranged on the camera lens of this camera head before.
Alternatively, in this box unit, be provided with four tail cages, be provided with between this tail cage for implementing the active clapboard layer that animal isolates between mutually.
Alternatively, the lateral surface of each this tail cage is provided with two bottle drinking devices.
Alternatively, this device also comprises: the angular surveying device is used for measuring the suspention angle of suspention animal.
Alternatively, the material of the box body wall of this box unit is the anti-reflectorized material of black.
Alternatively, this device also comprises: come off and detect and the information receiving and transmitting device, this comes off to detect with the information receiving and transmitting device and comprises: come off detecting unit and information receiving and transmitting unit, and wherein this computer system comprises: interface card and coffret; The image information of this camera head collection is imported this computer system through the multiway images card, by the experiment software in this computer system to image information analysis, processing with preserve in real time; When this checkout gear that comes off detects animal afterbody suspention and comes off, collect information through this detection that comes off with the detecting unit that comes off in the information receiving and transmitting device, and the information conveyance collected to the interface card of this computer system carried out information processing, through coffret information is sent to this information receiving and transmitting unit again, this information receiving and transmitting unit sends to information in the mode of short message the experimenter of appointment.
As shown from the above technical solution, embodiments of the invention have following beneficial effect:
(1) box unit comprises at least one tail cage, realize that a camera head is monitored in real time to the autonomic activities of the animal at least one the tail cage in the box unit synchronously and image extracts, but also can before the camera lens of camera head, Infrared Lens be set, by the interference of these other light of Infrared Lens filtering, improve the signal to noise ratio of image.
(2) can detect the suspention of animal afterbody by the checkout gear that comes off and whether come off, by computer system alarm signal be sent to the experimenter of appointment, realize coming off warning, make experimenter's intervention that can in time experimentize.
(3) by two bottle drinking devices are set at tail cage lateral surface, the condition that provides is provided in the syrup preference experiment that can be animal, realizes the detection to depression or the depressed behavior of class.
(4) between the tail cage in the box unit active clapboard layer can be set, the be obstructed exchange of isolation and non-isolation of the interchange that realizes animal.
Animal model multisample amount, time are long, the manual observation workload is big owing to fully taken into account, factors such as the preliminary treatment that comes off is untimely, the present invention can realize the real-time monitoring of the autonomic activities of the animal of afterbody suspention, come off and report to the police and detect the condition that provides for depression or the depressed behavior of class.Distance, speed, time three indexs are provided simultaneously, data such as the timesharing of motion and tranquillization two states, segmentation, subregion, and the information such as state of the afterbody of animal suspention, the real-time activity image of animal be can obtain, preserve and export in real time, thereby stability, the reliability of experiment guaranteed.
Description of drawings
Fig. 1 suspends the structure chart of real-time device for monitoring in midair for animal simulated weightlessness afterbody in the embodiments of the invention;
Fig. 2 is the theory diagram of computer system and other circuit in the embodiments of the invention.
Embodiment
For the purpose, technical scheme and the advantage that make the embodiment of the invention is clearer, below in conjunction with embodiment and accompanying drawing, the embodiment of the invention is done explanation in further detail.At this, illustrative examples of the present invention and explanation are used for explanation the present invention, but not as a limitation of the invention.
As shown in Figure 1, for animal simulated weightlessness afterbody in the embodiments of the invention suspends the structure chart of real-time device for monitoring in midair, this animal simulated weightlessness afterbody suspends real-time device for monitoring in midair and comprises:
Box unit 11, each box unit 11 comprises at least one tail cage 12, and this tail cage 12 is arranged in the box unit 11, and tail cage 12 is used for providing the space of animal afterbody suspention experiment, for example comprises four tail cages 12 in a box unit 11.
Alternatively, comprise eight box unit 11 in this device, this box unit 11 can be by a plurality of passive supports, form perpendicular to crossbeam and the housing of support, framework by support and crossbeam formation box unit 11 forms the box unit 11 of sealing by the housing that is arranged on the framework.The volume of this box unit 11 can be set to 63 * 55 * 74cm 3, what certainly can understand is not limit the concrete size of this box unit 11 in an embodiment of the present invention.
Alternatively, comprise four tail cages 12 in this box unit 11, the volume of this tail cage 12 can be set to 27 * 26 * 30cm 3, what certainly can understand is not limit the concrete size of this tail cage 12 in an embodiment of the present invention.
For the ease of observing the experiment situation of animal, the material of the top cover at the top of this tail cage 12 is lucite, but also can be at the groove of middle part setting " ten " font of top cover, makes the free movable unrestricted of afterbody suspention animal.
Camera head 13 is installed, the image information when being used for obtaining the animal afterbody suspention experiment in box unit 11 each tail cage 12 above each box unit 11.
Alternatively, at a crossbeam of box unit 11 this camera head 13 is set, this camera head 13 can be simultaneously extracts real-time monitoring and the image of the autonomic activities of animal in four tail cages 12 in the box unit 11 as shown in Figure 1.
There is a suspension apparatus 21 top of each tail cage 12, is used for being connected with the animal afterbody.
Alternatively, each tail cage 12 is provided with corresponding suspension apparatus 21, and as shown in Figure 1, a box unit 11 is provided with four suspension apparatus 21.
Whether at least one checkout gear 14 that comes off is used for detecting the suspention of animal afterbody and coming off when animal afterbody suspention experiment, when the afterbody that detects animal at the checkout gear 14 that comes off comes off, sends alarm signal.
Alternatively, this checkout gear 14 that comes off is separately positioned on the top of four tail cages 12 in the box unit 11, and for example the crossbeam in box unit 11 arranges four checkout gears 14 that come off.
In an embodiment of the present invention, whether can detect the animal afterbody by following dual mode comes off, mode one: whether this checkout gear 14 that comes off can detect the suspension apparatus 21 that is connected with the animal afterbody with closure by the disconnection of sense switch and come off from the checkout gear 14 that comes off, checkout gear 14 detects the switch disconnection if come off, represent that then suspension apparatus 21 comes off from the checkout gear 14 that comes off, checkout gear 14 detects switch closure if come off, and represents that then suspension apparatus 21 does not come off from the checkout gear 14 that comes off;
Mode two: whether the animal afterbody suspention that the checkout gear 14 that comes off detects on the suspension apparatus 21 comes off from suspension apparatus 21.Particularly, the checkout gear 14 of coming off detects for example tail chain sling of suspension apparatus 21() on pulling force, one end of tail chain sling is connected with the checkout gear 14 that comes off, the other end of tail chain sling is connected with the animal afterbody, when the animal afterbody does not come off, the checkout gear 14 that comes off can detect the pulling force on the tail chain sling, and when the animal afterbody came off, the checkout gear 14 that comes off detected less than the pulling force on the tail chain sling.
The computer system (not shown in figure 1) be used for to receive the alarm signal that the image information that camera head 13 sends and the checkout gear 14 that comes off send, and alarm signal is sent to the experimenter of appointment, makes experimenter's intervention that can in time experimentize.
Alternatively, after computer system received alarm signal, according to the corresponding relation of checkout gear 14 with number of animals that come off, the number of animals that will come off sent at least one terminal device of appointment by the mode of short message, the realization warning that comes off makes things convenient for the experimenter in time to intervene.
This animal afterbody suspends the autonomic activities situation that real-time device for monitoring can be monitored the afterbody suspention animal of larger samples amount in real time in midair, and experiment software analysis and the processing in the machine system as calculated, realizes the synchronous conversion of data; Moreover, adopt animal afterbody of the present invention to suspend real-time device for monitoring in midair, can accurately detect animal and be in tail and hang the state state that still comes off, when taking place as coming off, this device is alert notice in time, avoids the waste of sample, and the reliability and the authenticity that increase experiment.
Alternatively, the lateral surface of tail cage 12 is movable chamber door, food boxes 15 and two bottle drinking device 16 can be set on movable chamber door, provide food and water by food boxes 15 and two bottle drinking device 16 for animal, can provide the experiment of syrup preference that the condition that provides is provided for the animal of afterbody suspention, realize the detection to depression or the depressed behavior of class.
Alternatively, this device also comprises: at least one light emitting diode 17 and be used for powering to light emitting diode, and the power-supply system (not shown) of control light source, wherein light emitting diode 17 is arranged on the inboard of the tank wall of box unit 12, for example respectively establish at least one (for example 15) infrarede emitting diode in two inboards of the tank wall of box unit 12, this infrared diode is implemented in for a long time, under the various illumination conditions that continue to the extraction of independent activity of animals image, simultaneously before the camera lens of camera head 13, Infrared Lens is set, but by the interference of infrared other light of filter filtering, improve the signal to noise ratio of image.
Alternatively, be provided with active clapboard layer 18 between the tail cage 12, realize exchanging the exchange of be obstructed isolation and non-isolation by active clapboard layer 18, the bottom of this box unit 11 can be provided with aperture plate 19 and waste collection box 20.The material of the box body wall of this box unit 11 is the anti-reflectorized material of black.
Alternatively, this device also comprises: angular surveying device (not shown) is used for measuring the suspention angle of animal.
With reference to figure 2, be image monitoring and the alarm computer system that comes off.Simultaneously the autonomic activities of the suspention of the afterbody in four tail cages 12 in the box unit 11 animal is monitored in real time by camera head 13, the image information that camera head 13 is gathered can be through multiway images card 21 input computer systems 2, by 22 pairs of image information analyses of the experiment software in the computer system 2, processing and preservation in real time.
When the checkout gear 14 that comes off detects animal afterbody suspention and comes off, the detecting unit 31 collection information that come off in come off detection and information receiving and transmitting device 3, the information conveyance collected to the interface card (for example PCI-CAN card) 23 of computer system 2 is carried out information processing, through coffret (for example RS232 serial ports) 24 information is sent to information receiving and transmitting unit 32 again, information receiving and transmitting unit 32 sends to the experimenter of appointment in the mode of short message with warning message, realizes coming off warning.
As shown from the above technical solution, embodiments of the invention have following beneficial effect:
(1) box unit comprises at least one tail cage, a camera head is positioned at the box unit top, realization is monitored in real time to the autonomic activities of the animal of at least one tail cage in the box unit and image extracts, but also can before the camera lens of camera head, Infrared Lens be set, by the interference of these other light of Infrared Lens filtering, improve the signal to noise ratio of image.
(2) can be by the checkout gear that comes off, detect the suspention of animal afterbody and whether come off and realize coming off warning, by computer system alarm signal is sent to the experimenter of appointment, make experimenter's intervention that can in time experimentize.
(3) by two bottle drinking devices are set at tail cage lateral surface, the condition that provides is provided in the syrup preference experiment that can be animal, realizes the detection to depression or the depressed behavior of class.
(4) can establish the active clapboard layer between the tail cage in the box unit, the be obstructed exchange of isolation and non-isolation of the interchange that realizes animal.
Animal model multisample amount, time are long, the manual observation workload is big owing to fully taken into account, factors such as the preliminary treatment that comes off is untimely, the present invention can realize the real-time monitoring of the autonomic activities of the animal of afterbody suspention, come off and report to the police and detect the condition that provides for depression or the depressed behavior of class; Distance, speed, time three indexs are provided simultaneously, data such as the timesharing of motion and tranquillization two states, segmentation, subregion, and the information such as state of the afterbody of animal suspention, the real-time activity image of animal be can obtain, preserve and export in real time, thereby stability, the reliability of experiment guaranteed.
The above only is preferred embodiment of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims (9)

1. an animal simulated weightlessness afterbody suspends real-time device for monitoring in midair, it is characterized in that described device comprises:
At least one box unit, each box unit comprise at least one tail cage, and described tail cage is arranged in the box unit, are used for providing the space of animal afterbody suspention experiment;
The top of each box unit is equipped with camera head, the image information when being used for obtaining box unit animal afterbody suspention experiment;
The top of each tail cage is equipped with suspension apparatus, is used for being connected with the animal afterbody;
Whether each tail cage top is equipped with the checkout gear that comes off, be used for detecting the suspention of animal afterbody and coming off when animal afterbody suspention experiment, and when detecting the animal afterbody and come off, send alarm signal; And
Computer system is used for receiving the image information of described camera head transmission and the alarm signal that the described checkout gear that comes off sends, and described alarm signal is sent to the experimenter of appointment.
2. device according to claim 1, it is characterized in that, described device also comprises: at least one light emitting diode and being used for to described light emitting diode power supply, and the power-supply system of control light source, wherein said light emitting diode is arranged on the cage wall of described tail cage.
3. device according to claim 2 is characterized in that, described light emitting diode is infrarede emitting diode.
4. device according to claim 1 is characterized in that, described device also comprises: Infrared Lens, be arranged on the camera lens of described camera head before.
5. device according to claim 1 is characterized in that, is provided with four described tail cages in a described box unit, is provided with between the described tail cage for implementing the active clapboard layer that animal isolates between mutually.
6. device according to claim 5 is characterized in that, the lateral surface of each described tail cage is provided with two bottle drinking devices.
7. device according to claim 1 is characterized in that, described device also comprises: the angular surveying device is used for measuring the suspention angle of suspention animal.
8. device according to claim 1 is characterized in that, the material of the box body wall of described box unit is the anti-reflectorized material of black.
9. device according to claim 1, it is characterized in that, described device also comprises: come off and detect and the information receiving and transmitting device, the described detection that comes off comprises with the information receiving and transmitting device: come off detecting unit and information receiving and transmitting unit, and wherein said computer system comprises: interface card and coffret;
The image information of described camera head collection is imported described computer system through the multiway images card, by the experiment software in the described computer system to image information analysis, processing with preserve in real time; When the described checkout gear that comes off detects animal afterbody suspention and comes off, collect information through the described detection that comes off with the detecting unit that comes off in the information receiving and transmitting device, and the information conveyance collected to the interface card of described computer system carried out information processing, through coffret information is sent to described information receiving and transmitting unit again, described information receiving and transmitting unit sends to information in the mode of short message the experimenter of appointment.
CN201310228949.2A 2013-06-08 2013-06-08 The device of the weightless tail-suspension Real-Time Monitoring of a kind of animal imitating Expired - Fee Related CN103283623B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108782435A (en) * 2018-05-14 2018-11-13 南方医科大学 A kind of modeling method of puberty mouse animal models of depression
CN110352860A (en) * 2019-07-29 2019-10-22 广东省第二中医院(广东省中医药工程技术研究院) A kind of tail like chain mouse cage

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102129801A (en) * 2011-03-24 2011-07-20 宋昕宸 Intelligentized display device of simulated rat in simulated weightlessness condition
CN201905126U (en) * 2010-12-20 2011-07-27 中国人民解放军总医院 Simulation weightless tail-suspension device
CN102657101A (en) * 2012-04-16 2012-09-12 中国人民解放军63919部队 Non-human primate test animal medium and long-term weightlessness simulation model device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201905126U (en) * 2010-12-20 2011-07-27 中国人民解放军总医院 Simulation weightless tail-suspension device
CN102129801A (en) * 2011-03-24 2011-07-20 宋昕宸 Intelligentized display device of simulated rat in simulated weightlessness condition
CN102657101A (en) * 2012-04-16 2012-09-12 中国人民解放军63919部队 Non-human primate test animal medium and long-term weightlessness simulation model device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108782435A (en) * 2018-05-14 2018-11-13 南方医科大学 A kind of modeling method of puberty mouse animal models of depression
CN110352860A (en) * 2019-07-29 2019-10-22 广东省第二中医院(广东省中医药工程技术研究院) A kind of tail like chain mouse cage

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