CN110339296A - A kind of Chinese medicine composition and preparation method thereof of swelling and pain relieving traumatic injury - Google Patents
A kind of Chinese medicine composition and preparation method thereof of swelling and pain relieving traumatic injury Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine compositions and preparation method thereof of swelling and pain relieving traumatic injury, it is related to technical field of traditional Chinese medicines, raw material includes: 17-25 parts of cortex moutan, 22-30 parts of roxburgh peristrophe herb, 8-15 parts of myrrh, 8-15 parts of olibanum, 22-30 parts of decumbent corydalis tuber, 17-25 parts of champion bauhinia stem, 8-15 parts of bush, bone benefit broken 12-20 parts, 17-25 parts of Radix Melastomae, 12-20 parts of bletilla, 12-20 parts of madder, 0.4-1.0 parts of borneol, 0.4-1.2 parts of turpentine oil, 0.8-2 parts of wintergreen by weight.Each raw material reasonable compatibility of the present invention, synergy, all medicines share have the effect of thin channels and activating collaterals, invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain, clearing heat and cooling blood, can enhance blood circulation, make channels and collaterals are logical, qi and blood row and reach " no pain by smooth breath ", alleviating pain and detumescence effect is obvious；In addition, be prepared into external preparation, local disease position can be done directly on, rapidly, pain caused by ecchymoma is eliminated fast for efficacy of a drug infiltration, can be widely used for getting injured by a fall, wound, dampen, spraining etc. swelling pain caused by various traumatic injuries, tendon soft tissue injury and osteoarthropathy.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines more particularly to a kind of Chinese medicine compositions and its system of swelling and pain relieving traumatic injury
Preparation Method.
Background technique
Traumatic injury based on acute or chronic soft tissue injury is that common disease and high morbidity, injury are more in modern life
There is situations such as pain, swelling, bleeding or fracture, dislocation.Soft tissue injury is known as " injury of the tissues " in Chinese medicine.The soft tissues such as tendon are
Form the pith in joint, " miscellaneous diseases source stream rhinoceros candle " says that " muscle also, so beam section network bone, meat of stumbling stretches tight skin, for the pass of the whole body
Knob, the sporter of sharp entirety ".It adds: " total poly- place of muscle, then be knee ".Miraculous Pivot cloud: " all muscle persons, come under section ".
" so bending and stretching action, all muscle for it ".All traumatic injuries, muscle often stand in the breach, and injured chance is most.Clinically, it is all sprain,
After contusion, muscles can be caused to damage, partial gall, livid purple, joint joint stuffiness.In bone injury, since the soft tissues such as tendon are attached
Its surface, tendon is also often injured first, and sees that local swelling, the stasis of blood be green, joint stuffiness.For soft tissue injury, such as cannot
It obtains the effective treatment, will lead to old wound repeatedly, influence daily life and work.
It is mostly to damage to cause qi and blood stagnation that soft tissue injury, which studies carefully its interpretation of the cause, onset and process of an illness, channels and collaterals obstruction, part caused by a large amount of extravasated blood memories
Swelling, pain obvious, tissue bleeding, oedema etc.." General Records of Holy Universal Relief traumatics fracture door " say " if because traumatiing fracture, interior dynamic channels and collaterals, blood it
Road must not declare it is logical, siltation do not dissipate, then for swell be pain, control preferably removes evil become silted up, make qi and blood circulation, then can again peace ".Therefore, living
Blood stagnation resolvation and swelling and pain relieving are the fundamentums of the traumatic injury treatment based on soft tissue injury.But for now, market
The external medicine preparation or hospital preparation curative effect of upper treatment traumatic injury are not satisfactory, and there is working, slow, analgesic effect is unknown
Aobvious, preparation process is complicated, there is the problems such as certain irritation and side effect.
Summary of the invention
Technical problems based on background technology, the invention proposes a kind of Chinese traditional medicine compositions of swelling and pain relieving traumatic injury
Object and preparation method thereof, the Chinese medicine composition swelling and pain relieving effect is obvious, can be widely used for getting injured by a fall, wounding, dampen, spraining etc. each
Swelling pain caused by kind traumatic injury, tendon soft tissue injury and osteoarthropathy, and good effect, short treating period, safe side effect
It is small.
A kind of Chinese medicine composition of swelling and pain relieving traumatic injury proposed by the present invention, raw material includes: tree peony by weight
17-25 parts of skin, 22-30 parts of roxburgh peristrophe herb, 8-15 parts of myrrh, 8-15 parts of olibanum, 22-30 parts of decumbent corydalis tuber, 17-25 parts of champion bauhinia stem, Soviet Union
8-15 parts wooden, bone mends broken 12-20 parts, 17-25 parts of Radix Melastomae, 12-20 parts of bletilla, 12-20 parts of madder, 0.4-1.0 parts of borneol, pine
0.4-1.2 parts of fuel-economizing, 0.8-2 parts of wintergreen.
Preferably, raw material includes: 20 parts of cortex moutan, 27 parts of roxburgh peristrophe herb, 12 parts of myrrh, 12 parts of olibanum, summer by weight
It mends broken 17 parts, 20 parts of Radix Melastomae, 17 parts of bletilla, 17 parts of madder, borneol 0.7 without 27 parts, 20 parts of champion bauhinia stem, 10 parts of bush, bone
Part, 0.8 part of turpentine oil, 1.5 parts of wintergreen.
The invention also provides the preparation methods of the Chinese medicine composition of above-mentioned swelling and pain relieving traumatic injury, including following step
It is rapid:
S1, cortex moutan, myrrh, olibanum, champion bauhinia stem, bone are mended into broken, bletilla crushing, mixing, add 70-75% ethanol solution,
Refluxing extraction, filtering, obtains alcohol extracting filter residue and alcohol extract；
S2, roxburgh peristrophe herb, decumbent corydalis tuber, bush, Radix Melastomae, madder are crushed, alcohol extracting filter residue is added, mixing is added water to cook and mentioned
It takes, filters, obtain Aqueous extracts；
S3, ethyl alcohol is recovered under reduced pressure in alcohol extract, Aqueous extracts is then added, mixed, be concentrated under reduced pressure into medicinal extract；
S4, medicinal extract is mixed with borneol, turpentine oil, wintergreen, is prepared into any external preparation described in pharmacy
Type.
Preferably, in S1,5-8 times of 70-75% ethanol solution of dosing material initial mass, refluxing extraction 2-3h.
Preferably, in S2,6-10 times of water of dosing material initial mass decocts and extracts 1.5-3h.
Preferably, in S3, it is concentrated under reduced pressure into the medicinal extract that relative density at 50 DEG C is 1.14-1.18.
Preferably, in S4, exterior-applied formulation is ointment.
Preferably, ointment is prepared as follows: by glycerol, carbomer, Tween 80 and water wiring solution-forming, leaching is added
Cream, stirring adjust pH to 6.5 with triethanolamine aqueous solution, 50-60 DEG C are heated to, as water phase；By turpentine oil, wintergreen, ice
Piece, azone mixing, stirring, as oily phase；During the oil phase is added to the aqueous phase, stirring is dispensed to get ointment.
Preferably, the specification of the ointment of preparation is 0.35-0.40g crude drug/g ointment.
It is as follows the effect of each material medicine in the present invention:
Cortex moutan: cold nature, bitter, pungent, thoughts of returning home warp, Liver Channel, kidney channel have the effect of clearing heat and cooling blood, activating microcirculation and removing stasis medicinal；With
Control febrile virulent maculae, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to yin, amenorrhea and algomenorrhea, carbuncle sore tumefacting virus, injuries from falls as well.
Roxburgh peristrophe herb: cold in nature, acrid flavour, hardship, it is distributed in lung channel, there is the effect of clearing heat and detoxicating, cool blood out the wind, eliminating stasis to subdue swelling；It cures mainly
Cough with lung heat, tuberculosis hemoptysis are spitted blood, child convulsion, pharyngitis, aphthae, urine leaching pain, carbuncle swells boil, scrofula, bruise
Swelling and pain, traumatic hemorrhage, venomous snake bite.
Myrrh: mild-natured, acrid flavour, hardship, thoughts of returning home warp, Liver Channel, the spleen channel have the effect of scattered stasis pain, detumescence and promoting granulation；For chest
Numbness is pained, gastral cavity pain, dysmenorrhea menostasis, postpartum stasis , abdominal mass and abdominal pain, rheumatic arthralgia, traumatic injury, carbuncle swells sore.
Olibanum: warm-natured, acrid flavour, hardship, thoughts of returning home warp, the spleen channel, Liver Channel have the effect of regulating qi and activating blood, analgesic therapy, detumescence, myogenic；
With controlling stagnation of QI-blood, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, rheumatic arthralgia, dysmenorrhea, postpartum blood stasis stabbing pain.Clinic is also used to
Treat acute appendicitis.
Decumbent corydalis tuber: warm-natured, bitter, micro-pungent, return liver warp have the effect of promoting blood circulation, dredging collateral, promoting qi circulation and relieving pain；With controlling middle windage yaw
Paralysis, sequelae of infantile paralysis, sciatica, rheumatic arthritis, traumatic injury, lumbar muscle strain etc..
Champion bauhinia stem: warm-natured, sweet in flavor, slight bitter has the effect of dispelling wind and eliminating dampness, the promoting flow of qi and blood circulation；Cure mainly rheumatic arthralgia, bruise damage
Wound, hemiplegia, epigastric pain, infantile malnutrition due to digestive disturbances or intestinalparasites, dysentery.
Bush: mild-natured, sweet in flavor, salty, thoughts of returning home warp, Liver Channel, the spleen channel have the effect of promoting circulation of blood dissolving stasis, swelling and pain relieving；Fallen with controlling
Damage is played, the injury of tendon and muscle of fracturing, the stagnant swelling and pain of the stasis of blood, amenorrhea and algomenorrhea, postpartum stasis, chest and abdomen shouting pain, ulcer sore pain.
Bone is mended broken: warm-natured, bitter, return liver warp, kidney channel have the effect of continues and hinders pain relieving, The strong bone of kidney tonifying；With controlling kidney deficiency waist
Bitterly, toothache, tinnitus, chronic diarrhea, traumatic injury, alopecia areata, corn etc..
Radix Melastomae: mild-natured, taste is slightly sour, puckery, and distributed in lung channel, the spleen channel, Liver Channel have the effect of promoting blood circulation and removing obstruction in channels, astringing to arrest bleeding；With
Control rheumatic arthralgia, pain in waist and lower extremities, postpartum abdominal pain, metrorrhagia and metrostaxis leukorrhagia, traumatic hemorrhage.
Bletilla: cold nature, bitter, sweet, puckery, distributed in lung channel, Liver Channel, stomach meridian have the effect of astringing to arrest bleeding, detumescence and promoting granulation；
With control hemoptysis spit blood, pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Madder: cold in nature, bitter, return liver warp have the effect of cool blood, hemostasis, dissolving stasis, promoting menstruation；For treating haematemesis, nosebleed
Blood, metrorrhagia and metrostaxis, traumatic hemorrhage, the resistance of menostasis block up, arthralgia, tumbling and swelling.
Borneol: cold in nature, acrid flavour, hardship, thoughts of returning home warp, the spleen channel, lung channel have the effect of inducing resuscitation of having one's ideas straightened out, clearing away heat to and alleviating pain；With controlling heat
Close coma, close in phlegm heat, hot summer weather soldier faints, child convulsion and various sore, carbuncle and painful swellings, burst after do not hold back, burn and scald, abscess of throat, larynx
Numbness, red eye, swell pain, aphthae etc..
Turpentine oil: turpentine oil, which has, promotes local blood circulation, alleviates swelling and slight analgesic effect, is for mitigating flesh
Feel sorry, arthralgia, neuralgia and strain.
Wintergreen: wintergreen has the effects of improving blood circulation, enhancing endocrine, reinforcing bone ilium, protection skin, can be used for
Courbature, arthralgia, neuralgia.
The utility model has the advantages that the invention proposes a kind of Chinese medicine compositions of swelling and pain relieving traumatic injury, in line with " promoting blood circulationization
The stasis of blood, swelling and pain relieving " be the basic rules for the treatment of, select cortex moutan, roxburgh peristrophe herb, myrrh, olibanum, decumbent corydalis tuber, champion bauhinia stem, bush, bone mend it is broken,
The raw materials such as Radix Melastomae, bletilla, madder, borneol, turpentine oil, wintergreen, reasonable compatibility, synergy between each raw material, all medicines close
With there is the effect of thin channels and activating collaterals, invigorating circulation of blood to dissipate blood stasis and reducing swelling and relieving pain, clearing heat and cooling blood, blood circulation can be enhanced, lead to channels and collaterals, qi and blood
It goes and reaches " no pain by smooth breath ", alleviating pain and detumescence effect is obvious；In addition, being prepared into external preparation, local disease position can be done directly on,
Rapidly, pain caused by ecchymoma is eliminated fastly for efficacy of a drug infiltration, can be widely used for the various traumatic injuries, tendon such as getting injured by a fall, wound, dampen, spraining
Swelling pain caused by soft tissue injury and osteoarthropathy, and good effect, short treating period, safe Small side effects, preparation method is simple,
Easy practice and extension.
Specific embodiment
In the following, technical solution of the present invention is described in detail by specific embodiment.
Embodiment 1
A kind of Chinese medicine composition of swelling and pain relieving traumatic injury proposed by the present invention, raw material includes: tree peony by weight
17 parts of skin, 30 parts of roxburgh peristrophe herb, 8 parts of myrrh, 8 parts of olibanum, 30 parts of decumbent corydalis tuber, 17 parts of champion bauhinia stem, 15 parts of bush, bone mend it is broken 12 parts,
17 parts of Radix Melastomae, 20 parts of bletilla, 20 parts of madder, 0.4 part of borneol, 0.4 part of turpentine oil, 2 parts of wintergreen.
The invention also provides the preparation methods of the Chinese medicine composition of above-mentioned swelling and pain relieving traumatic injury, including following step
It is rapid:
S1, cortex moutan, myrrh, olibanum, champion bauhinia stem, bone are mended broken, bletilla crush, mixing, 5 times of dosing material initial mass
70% ethanol solution, refluxing extraction 2h, filtering obtain alcohol extracting filter residue and alcohol extract；
S2, roxburgh peristrophe herb, decumbent corydalis tuber, bush, Radix Melastomae, madder are crushed, alcohol extracting filter residue is added, mixes, dosing material is initial
6 times of water of quality, decocts and extracts 1.5h, and filtering obtains Aqueous extracts；
S3, ethyl alcohol is recovered under reduced pressure in alcohol extract, Aqueous extracts is then added, mixed, be concentrated under reduced pressure into relative density at 50 DEG C
For 1.14 medicinal extract；
S4, by glycerol, carbomer, Tween 80 and water wiring solution-forming, medicinal extract, stirring, with triethanolamine aqueous solution tune is added
PH to 6.5 is saved, 50 DEG C are heated to, as water phase；Turpentine oil, wintergreen, borneol, azone are mixed, stirring, as oil
Phase；During the oil phase is added to the aqueous phase, stirring, to get ointment, ointment specification is 0.35g crude drug/g ointment for packing.
Embodiment 2
A kind of Chinese medicine composition of swelling and pain relieving traumatic injury proposed by the present invention, raw material includes: tree peony by weight
25 parts of skin, 22 parts of roxburgh peristrophe herb, 15 parts of myrrh, 15 parts of olibanum, 22 parts of decumbent corydalis tuber, 25 parts of champion bauhinia stem, 8 parts of bush, bone mend it is broken 20 parts,
25 parts of Radix Melastomae, 12 parts of bletilla, 12 parts of madder, 1.0 parts of borneol, 1.2 parts of turpentine oil, 0.8 part of wintergreen.
The invention also provides the preparation methods of the Chinese medicine composition of above-mentioned swelling and pain relieving traumatic injury, including following step
It is rapid:
S1, cortex moutan, myrrh, olibanum, champion bauhinia stem, bone are mended broken, bletilla crush, mixing, 8 times of dosing material initial mass
75% ethanol solution, refluxing extraction 3h, filtering obtain alcohol extracting filter residue and alcohol extract；
S2, roxburgh peristrophe herb, decumbent corydalis tuber, bush, Radix Melastomae, madder are crushed, alcohol extracting filter residue is added, mixes, dosing material is initial
10 times of water of quality, decocts and extracts 3h, and filtering obtains Aqueous extracts；
S3, ethyl alcohol is recovered under reduced pressure in alcohol extract, Aqueous extracts is then added, mixed, be concentrated under reduced pressure into relative density at 50 DEG C
For 1.18 medicinal extract；
S4, by glycerol, carbomer, Tween 80 and water wiring solution-forming, medicinal extract, stirring, with triethanolamine aqueous solution tune is added
PH to 6.5 is saved, 60 DEG C are heated to, as water phase；Turpentine oil, wintergreen, borneol, azone are mixed, stirring, as oil
Phase；During the oil phase is added to the aqueous phase, stirring, to get ointment, ointment specification is 0.40g crude drug/g ointment for packing.
Embodiment 3
A kind of Chinese medicine composition of swelling and pain relieving traumatic injury proposed by the present invention, raw material includes: tree peony by weight
22 parts of skin, 25 parts of roxburgh peristrophe herb, 10 parts of myrrh, 13 parts of olibanum, 25 parts of decumbent corydalis tuber, 22 parts of champion bauhinia stem, 12 parts of bush, bone mend broken 15
Part, 22 parts of Radix Melastomae, 16 parts of bletilla, 15 parts of madder, 0.6 part of borneol, 1 part of turpentine oil, 1.5 parts of wintergreen.
The invention also provides the preparation methods of the Chinese medicine composition of above-mentioned swelling and pain relieving traumatic injury, including following step
It is rapid:
S1, cortex moutan, myrrh, olibanum, champion bauhinia stem, bone are mended broken, bletilla crush, mixing, 6 times of dosing material initial mass
72% ethanol solution, refluxing extraction 2h, filtering obtain alcohol extracting filter residue and alcohol extract；
S2, roxburgh peristrophe herb, decumbent corydalis tuber, bush, Radix Melastomae, madder are crushed, alcohol extracting filter residue is added, mixes, dosing material is initial
7 times of water of quality, decocts and extracts 2h, and filtering obtains Aqueous extracts；
S3, ethyl alcohol is recovered under reduced pressure in alcohol extract, Aqueous extracts is then added, mixed, be concentrated under reduced pressure into relative density at 50 DEG C
For 1.15 medicinal extract；
S4, by glycerol, carbomer, Tween 80 and water wiring solution-forming, medicinal extract, stirring, with triethanolamine aqueous solution tune is added
PH to 6.5 is saved, 55 DEG C are heated to, as water phase；Turpentine oil, wintergreen, borneol, azone are mixed, stirring, as oil
Phase；During the oil phase is added to the aqueous phase, stirring, to get ointment, ointment specification is 0.36g crude drug/g ointment for packing.
Embodiment 4
A kind of Chinese medicine composition of swelling and pain relieving traumatic injury proposed by the present invention, raw material includes: tree peony by weight
20 parts of skin, 27 parts of roxburgh peristrophe herb, 12 parts of myrrh, 12 parts of olibanum, 27 parts of decumbent corydalis tuber, 20 parts of champion bauhinia stem, 10 parts of bush, bone mend broken 17
Part, 20 parts of Radix Melastomae, 17 parts of bletilla, 17 parts of madder, 0.7 part of borneol, 0.8 part of turpentine oil, 1.5 parts of wintergreen.
The invention also provides the preparation methods of the Chinese medicine composition of above-mentioned swelling and pain relieving traumatic injury, including following step
It is rapid:
S1, cortex moutan, myrrh, olibanum, champion bauhinia stem, bone are mended broken, bletilla crush, mixing, 7 times of dosing material initial mass
70% ethanol solution, refluxing extraction 2.5h, filtering obtain alcohol extracting filter residue and alcohol extract；
S2, roxburgh peristrophe herb, decumbent corydalis tuber, bush, Radix Melastomae, madder are crushed, alcohol extracting filter residue is added, mixes, dosing material is initial
8 times of water of quality, decocts and extracts 2.5h, and filtering obtains Aqueous extracts；
S3, ethyl alcohol is recovered under reduced pressure in alcohol extract, Aqueous extracts is then added, mixed, be concentrated under reduced pressure into relative density at 50 DEG C
For 1.16 medicinal extract；
S4, by glycerol, carbomer, Tween 80 and water wiring solution-forming, medicinal extract, stirring, with triethanolamine aqueous solution tune is added
PH to 6.5 is saved, 60 DEG C are heated to, as water phase；Turpentine oil, wintergreen, borneol, azone are mixed, stirring, as oil
Phase；During the oil phase is added to the aqueous phase, stirring, to get ointment, ointment specification is 0.38g crude drug/g ointment for packing.
The present invention routinely can also be prepared into other exterior-applied formulations such as patch agent by preparation process.
It is examined through Composition analyzed and clinical case, the Chinese medicine composition effect in embodiment 4 is best.
The present invention is to 260 because of the traumatic injuries such as strain, shock, strain, tumble injury, extravasated blood, tendon soft tissue injury, part
The swelling pain of injury caused by extravasated blood swelling and pain, bone fracture, old wound etc. carries out clinical treatment, and application method is that ointment is applied to trouble
Place, it is 2-4 times daily, it is aided with certain massage.The ointment curative effect rapidly, significant effect, radical cure is thoroughly, efficient up to 99.2%.
Wherein, to sprain, fall flutter, hit, extravasated blood etc., embrocating in the short time can relieve pain, reduce swelling, and can fully recover from an illness in soft tissue injury 7 days
More；To swelling pain of injury etc. caused by bone fracture, old wound etc., after embrocating one day, pain is substantially reduced, after embrocating 3-5 days, acid
Bitterly, swelling and pain all disappear, and without rebound phenomenon, to that more than 3 courses for the treatment of of oldness soft tissue injury can fully recover, each course for the treatment of is
7 days.
Typical case:
Case 1: Mr. Wang, male, 22 years old, thigh was wounded by other side's knee when playing basketball, and swelling and pain are become silted up green at thigh, can not under
It squats, the soft tissue injury through medical check thigh position 3 times a day, is aided with certain massage using the ointment of embodiment 4, applies
After wiping 1 day, pain is substantially reduced, and detumescence effect is obvious, and after embrocating 3 days, swelling, extravasated blood disappear, and can walk.
Case 2: Jiang, female 45 years old, are accidentally turned round when removing weight to waist, untreated, Low Back Pain aggravates after 4 days, to hospital
For chronic lumbar vertebrae strain, using the ointment of embodiment 4,3 times a day, it is aided with certain massage, after embrocating 1 day, pain obviously subtracts
Gently, and after embrocating 5 days, state of an illness recovery from illness.
The foregoing is only a preferred embodiment of the present invention, but scope of protection of the present invention is not limited thereto,
Anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention and its
Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (9)
1. a kind of Chinese medicine composition of swelling and pain relieving traumatic injury, which is characterized in that its raw material includes: cortex moutan by weight
17-25 parts, 22-30 parts of roxburgh peristrophe herb, 8-15 parts of myrrh, 8-15 parts of olibanum, 22-30 parts of decumbent corydalis tuber, 17-25 parts of champion bauhinia stem, bush
8-15 parts, bone benefit broken 12-20 parts, 17-25 parts of Radix Melastomae, 12-20 parts of bletilla, 12-20 parts of madder, 0.4-1.0 parts of borneol, turpentine
It is 0.4-1.2 parts oily, 0.8-2 parts of wintergreen.
2. the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 1, which is characterized in that its raw material is by weight
Part includes: 20 parts of cortex moutan, 27 parts of roxburgh peristrophe herb, 12 parts of myrrh, 12 parts of olibanum, 27 parts of decumbent corydalis tuber, 20 parts of champion bauhinia stem, bush 10
Part, bone mend broken 17 parts, 20 parts of Radix Melastomae, 17 parts of bletilla, 17 parts of madder, 0.7 part of borneol, 0.8 part of turpentine oil, 1.5 parts of wintergreen.
3. a kind of preparation method of the Chinese medicine composition based on swelling and pain relieving traumatic injury of any of claims 1 or 2, feature
It is, comprising the following steps:
S1, cortex moutan, myrrh, olibanum, champion bauhinia stem, bone are mended into broken, bletilla crushing, mixing, adds 70-75% ethanol solution, flows back
It extracts, filtering obtains alcohol extracting filter residue and alcohol extract；
S2, roxburgh peristrophe herb, decumbent corydalis tuber, bush, Radix Melastomae, madder are crushed, alcohol extracting filter residue is added, mixing adds water to cook extraction, mistake
Filter, obtains Aqueous extracts；
S3, ethyl alcohol is recovered under reduced pressure in alcohol extract, Aqueous extracts is then added, mixed, be concentrated under reduced pressure into medicinal extract；
S4, medicinal extract is mixed with borneol, turpentine oil, wintergreen, is prepared into any exterior-applied formulation described in pharmacy.
4. the preparation method of the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 3, which is characterized in that S1
In, 5-8 times of 70-75% ethanol solution of dosing material initial mass, refluxing extraction 2-3h.
5. the preparation method of the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 3, which is characterized in that S2
In, 6-10 times of water of dosing material initial mass decocts and extracts 1.5-3h.
6. the preparation method of the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 3, which is characterized in that S3
In, it is concentrated under reduced pressure into the medicinal extract that relative density at 50 DEG C is 1.14-1.18.
7. the preparation method of the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 3, which is characterized in that S4
In, exterior-applied formulation is ointment.
8. the preparation method of the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 7, which is characterized in that soft
Paste is prepared as follows: by glycerol, carbomer, Tween 80 and water wiring solution-forming, medicinal extract is added, triethanolamine is used in stirring
Aqueous solution adjusts pH to 6.5,50-60 DEG C is heated to, as water phase；Turpentine oil, wintergreen, borneol, azone are mixed, stirred
It mixes, as oily phase；During the oil phase is added to the aqueous phase, stirring is dispensed to get ointment.
9. the preparation method of the Chinese medicine composition of swelling and pain relieving traumatic injury according to claim 8, which is characterized in that system
The specification of standby ointment is 0.35-0.40g crude drug/g ointment.
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| CN1267545A (en) * | 1999-12-22 | 2000-09-27 | 尹霞林 | Medicine for injury pain and its preparation |
| CN103385985A (en) * | 2012-05-11 | 2013-11-13 | 石荣斌 | Chinese herbal medicine composition for quick connection of muscles and bones |
| CN104688893A (en) * | 2015-03-21 | 2015-06-10 | 济南鸿飞生物技术有限公司 | Medicated bath decoction for treating cold-damp invasion type external humeral epicondylitis and preparation method thereof |
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Application publication date: 20191018 |