CN110327482A - A kind of medical dressing sheet, the medical dressing device being prepared by it and preparation method - Google Patents
A kind of medical dressing sheet, the medical dressing device being prepared by it and preparation method Download PDFInfo
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- CN110327482A CN110327482A CN201910624453.4A CN201910624453A CN110327482A CN 110327482 A CN110327482 A CN 110327482A CN 201910624453 A CN201910624453 A CN 201910624453A CN 110327482 A CN110327482 A CN 110327482A
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- medical dressing
- dressing
- alginate
- medical
- sheet
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive plasters or dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/225—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Abstract
The medical dressing device and preparation method being prepared the present invention relates to a kind of medical dressing sheet, by it, including using alginate dressing, the alginate dressing is made of alginate fiber, it is characterized in that, being attached with micropore polysaccharide particle on the fiber of the one side in the both side surface of the alginate dressing.Medical dressing sheet and medical dressing device of the invention is easy to use; and preparation method of the invention is easy to operate; it is good with adhesive bandage; stability is strong; it being capable of quick closure soft tissue wound; it is wide to adapt to surface of a wound range; use environment is unrestricted; it can absorbed themselves; it will not stick together with the surface of a wound, prevent cicatricial tissue hyperplasia, can quickly and effectively control wound bed fluid exudation; play the role of protecting the surface of a wound, promote healing, is pre- aseptic, is had a very important significance in emergency care of trauma for saving the life of the wounded.
Description
Technical field:
The present invention relates to biological medicine Material Field, specially a kind of medical dressing sheet, the Medical coating being prepared by it
Expect device and preparation method.
Background technique:
Medical market medical dressing is many kinds of, has a single function, and is easily destroyed the granulation tissue that the surface of a wound is newly grown, and influences to create
The reparation in face has the risk for leading to scar scar hyperplasia, using limited.With the further intensification to wound repair Mechanism Study,
Medical dressing is prepared using various absorbable hemostatic materials to come into being.Currently, absorbable polysaccharide hemostatic material, solvable
The alginic acid salt hemostatic material and compound hemostatic material of solution are the hot spots of research.Alginate hemostatic material can largely absorb wound
The liquid body exudate in face keeps wound to be in a kind of wet environment, prevents diffusate from oozing out, be conducive to the healing of the surface of a wound.It is domestic
Outer scholar, which studies, finds that single alginate dressing haemostatic effect is unsatisfactory, how to improve the medical effect of alginate dressing
Fruit is the important topic of people's research.There is researcher Chinese herbal medicine, blood-clotting agent, antibacterials etc. and the compound preparation of alginate
Various functional medical dressing out.Such as: calcium alginate fibre combine dressing, sodium rice silver calcium alginate dressing and chitosan and sea
Calcium alginate compound bio dressing etc..And it uses micropore polysaccharide and calcium alginate to bind directly and prepares multifunctional medical applicator
Method have no pertinent literature report.
A kind of Chinese invention patent (application number 201310567360.5) " preparation side of calcium alginate fibre combine dressing
Method ", it uses calcium alginate fibre for primary raw material, debridement raw material is mixed into sea algae calcium fiber, antibacterial and anti-inflammatory raw material is made
Medical calcium alginate fiber composite dressing；" sodium rice silver calcium alginate is anti-for Chinese invention patent (application number 200610053877.2)
Bacterium dressing ", it is that sodium rice silver paste is sprayed to re-dry on calcium alginate dressing to be prepared into sodium rice silver calcium alginate antibacterial dressing；In
" a kind of carboxymethyl chitosan and calcium alginate compounded biology apply state's utility model patent patent (application number 201220183433.1)
Material ", it is uniformly to mix carboxymethyl chitosan fiber and calcium alginate fibre difference cutting short-forming fiber, with spray with certain proportion
The ethanol solution of the silver containing sodium rice is sprayed on fiber by day with fog, is prepared through needle thorn, hot press drying；Personal dipping also is rich
Collection method prepares silver-carrying calcium alginate antiseptic dressing etc..Since these plyability functional dressings are in recombination process, addition it is antibacterial,
Anti-inflammation drugs it is all kinds of various, clinical application effect is not very ideal；Nano-silver loaded mixes nano silver into calcium alginate
The calcium alginate compounded dressing in sea afterwards can significantly inhibit staphylococcus aureus and pneumobacillus, but the addition of nano silver,
There is certain cytotoxicity for human body fibroblast, the proinflammatory cytokines of macrophage release will substantially reduce, and
The country such as America and Europe has limited use；Chitosan in the calcium alginate compounded dressing of chitosan be from the crusts such as shrimp crab extract preparation and
At, there are the potential factors for inducing allergy.
Summary of the invention:
The unfavorable factor of wound healing and controlling for the high exudative surface of a wound are potentially influenced to solve to exist in combine dressing
It treats and micropore polysaccharide powder is directly sprayed onto the preparation of alginate dressing surface by the problem of nursing, the present invention by a certain percentage
At micropore polysaccharide alginates medical multifunctional dressing, which does not change polysaccharide and the respective physics of alginate, chemistry
Property has potent effect.Wound fluid can be absorbed rapidly applied to the exudative surface of a wound of soft tissue, form hydrated gel protection wound
Face, double-hemostasis function, double-absorption diffusate, the duplicate protection surface of a wound.Micropore polysaccharide absorptive tissue liquid under the action of enzyme quickly
It is degraded to monosaccharide, final metabolite is CO2And H2O provides nutrient for the increment of endothelial cell；Alginate absorbs diffusate
It can be degraded to small molecular sugar aldehydic acid, uronic acid can promote the increment of endothelial cell, the metabolic capabilities of cell are improved,
Increase the reproduction speed of neoblast, promotes Wound healing；Therefore, there is dual wound healing, effectively prevent scar tissue
Hyperplasia.
It is specially adapted to the wound largely oozed out, the surface of a wound, such as: all kinds of bleeding surface of a wound, ulcer wound surface, infective wound surface, burn
The surface of a wound and the pressure sore surface of a wound etc..
For the above-mentioned purpose for reaching one side, the specific technical solution of the present invention is as follows:
A kind of medical dressing sheet, including alginate dressing is used, the alginate dressing is by alginate fiber system
At being attached with micropore polysaccharide particle on the fiber of the one side in the both side surface of the alginate dressing.
Preferably, the micropore polysaccharide and the mass ratio of the alginate dressing are (0.01~0.5): 1.
Further, the micropore polysaccharide and the mass ratio of the alginate dressing are (0.05~0.2): 1.
Further, the micropore polysaccharide is prepared by converted starch, and the converted starch becomes selected from potato plants
One of property starch, cassava modified starch, modified corn starch are a variety of.
Preferably, the medical dressing sheet is with a thickness of 0.5-5mm.
Further, the medical dressing sheet is with a thickness of 1-1.5mm.
Preferably, the alginate is calcium alginate.
For the above-mentioned purpose for reaching another aspect, the specific technical solution of the present invention is as follows:
A kind of medical dressing device, the medical dressing device include hard vacuum formed box, medical dressing sheet, the Medical coating
For tablet loaded in the hard vacuum formed box, the medical dressing sheet is above-mentioned medical dressing sheet.
Preferably, the medical dressing sheet includes dressing layer and release layer, is attached with the one of micropore polysaccharide in dressing layer
Side is provided with release layer.
Preferably, the medical dressing device includes aluminium foil bag, and the medical dressing sheet is loaded in the hard vacuum formed box,
It is reloaded into the aluminium foil bag.
Preferably, the medical dressing device includes aluminium plastic bag, and the medical dressing sheet is loaded in the hard vacuum formed box,
It is reloaded into the aluminium plastic bag, the aluminium plastic bag is made of aluminium plastic material, and the aluminium plastic material is the one side or two sides in aluminium foil
Coated with plastics.
Preferably, the medical dressing device includes PETG bags, and the medical dressing sheet is loaded in the hard vacuum formed box,
It is reloaded into PETG bags described, described PETG bags is made of PETG material.
For the above-mentioned purpose for reaching another aspect, the specific technical solution of the present invention is as follows:
It is a kind of to prepare the preparation method such as above-mentioned medical dressing device, comprising the following steps:
(1) micropore polysaccharide powder is uniformly sprayed on a surface in two surfaces of alginate dressing, prepared
At micropore polysaccharide alginate dressing, the alginate dressing is made of alginate fiber；
(2) the then composition material of the micropore polysaccharide alginate dressing and release layer fitting, so that the institute formed
It states release layer and is in the side that the micropore polysaccharide alginate dressing is attached with micropore polysaccharide, so that medical dressing be made
Piece；
(3) medical dressing sheet is cut by certain size, then loaded in PETG hard vacuum formed box.
Preferably, the medical dressing sheet after being loaded in PETG hard vacuum formed box by the method, with aluminium foil bag or aluminium
Mould bag packaging, Co60-r radiation sterilization.
Preferably, the method is packed after the medical dressing sheet is loaded in PETG hard vacuum formed box with PETG bags,
Co60-r radiation sterilization.
Compared with prior art, easy to operate the beneficial effects of the present invention are: multifunctional medical dressing is easy to use, with
Adhesive bandage is good, and stability is strong, can quick closure soft tissue wound, adapt to surface of a wound range it is wide, use environment is unrestricted,
Can absorbed themselves, will not stick together with the surface of a wound, prevent cicatricial tissue hyperplasia, can quickly and effectively control wound bed fluid exudation,
Play the role of protecting the surface of a wound, promote healing, is pre- aseptic, for saving the life of the wounded with very heavy in emergency care of trauma
The meaning wanted.
Detailed description of the invention
Fig. 1 is a kind of structural schematic diagram of medical dressing sheet,
Fig. 2 is a kind of composed structure schematic diagram of medical dressing device,
Wherein, 1- hard vacuum formed box box cover, 2- release layer, 3- micropore polysaccharide powder, 4- alginate dressing, 5- hard
Vacuum formed box cassette bottom.
Specific embodiment:
The principles and features of the present invention are described below, and the given examples are served only to explain the present invention, is not intended to limit
Determine the scope of the present invention.
Prepare material used in medical dressing sheet of the invention, alginate dressing, micropore polysaccharide, release layer group become a useful person
Material can be obtained from commercially available.
Embodiment 1
A kind of medical dressing sheet, including alginate dressing is used, the alginate dressing is by alginate fiber system
At being attached with micropore polysaccharide particle on the fiber of the one side in the both side surface of the alginate dressing；
In this fact Example, the micropore polysaccharide powder of -300 mesh of 50 mesh is uniformly sprayed by alginate fiber system
At on the side surface in the both side surface of alginate dressing, another side surface does not spray micropore polysaccharide powder, the micropore
Polysaccharide is prepared using converted starch, and converted starch includes potato plants converted starch, cassava modified starch, corn change
Property starch etc., the ratio of micropore polysaccharide and calcium alginate is 0.01~0.5:1, preferably 0.1:1, prepares slabbing polysaccharide sea
Alginate dressing, with a thickness of 0.5~5mm, preferably 1-2mm, more preferably 1-1.5mm.
A kind of medical dressing device, the medical dressing device include hard vacuum formed box, medical dressing sheet, the Medical coating
For tablet loaded in the hard vacuum formed box, the medical dressing sheet is above-mentioned medical dressing sheet.
In this fact Example, the above-mentioned medical dressing sheet that medical dressing device uses includes dressing layer and release layer, is being applied
The side that the bed of material is attached with micropore polysaccharide is provided with release layer.
It is a kind of to prepare the preparation method such as above-mentioned medical dressing device, comprising the following steps:
(1) micropore polysaccharide powder is uniformly sprayed on a surface in two surfaces of alginate dressing, prepared
At micropore polysaccharide alginate dressing, the alginate dressing is made of alginate fiber；
(2) the then composition material of the micropore polysaccharide alginate dressing and release layer fitting, so that the institute formed
It states release layer and is in the side that the micropore polysaccharide alginate dressing is attached with micropore polysaccharide, so that medical dressing be made
Piece；
(3) medical dressing sheet is cut by certain size, then loaded in PETG hard vacuum formed box.
Embodiment 2
Embodiment 2 the difference from embodiment 1 is that, the medical dressing sheet of embodiment 2 is cut by certain size, then
After in PETG hard vacuum formed box, packed with aluminium foil bag, aluminium plastic bag or PETG bag；Effect is that dressing sheet of the invention fills
In in hard vacuum formed box, being reloaded into aluminium foil bag, aluminium plastic bag or PETG bags of packagings, medical dressing device of the invention is used
In more extensive environment, especially wet environment, it is easier to keep the germ-free condition of medical dressing sheet；Do not have in example 2
List other the relevant technologies features, reference implementation example 1.
A kind of medical dressing sheet, including alginate dressing is used, the alginate dressing is by alginate fiber system
At being attached with micropore polysaccharide particle on the fiber of the one side in the both side surface of the alginate dressing；
In the present embodiment, the micropore polysaccharide powder of -300 mesh of 200 mesh is uniformly sprayed onto the table of calcium alginate dressing
The ratio of face, micropore polysaccharide and calcium alginate is 0.5:1, prepares slabbing polysaccharide calcium alginate dressing, with a thickness of
1.5mm。
A kind of medical dressing device, the medical dressing device include hard vacuum formed box, medical dressing sheet, the Medical coating
For tablet loaded in the hard vacuum formed box, the medical dressing sheet is above-mentioned medical dressing sheet.
It is a kind of to prepare the preparation method such as above-mentioned medical dressing device, comprising the following steps:
(1) micropore polysaccharide powder is uniformly sprayed on a surface in two surfaces of alginate dressing, prepared
At micropore polysaccharide alginate dressing, the alginate dressing is made of alginate fiber；
(2) the then composition material of the micropore polysaccharide alginate dressing and release layer fitting, so that the institute formed
It states release layer and is in the side that the micropore polysaccharide alginate dressing is attached with micropore polysaccharide, so that medical dressing be made
Piece；
(3) medical dressing sheet is cut by certain size, then loaded in PETG hard vacuum formed box；
Preferably, the medical dressing sheet after being loaded in PETG hard vacuum formed box by the method, with aluminium foil bag or aluminium
Mould bag packaging, Co60-r radiation sterilization；
Preferably, the method is packed after the medical dressing sheet is loaded in PETG hard vacuum formed box with PETG bags,
Co60-r radiation sterilization.
In the present embodiment, the micropore polysaccharide powder of -300 mesh of 200 mesh is uniformly sprayed onto the table of calcium alginate dressing
The ratio of face, micropore polysaccharide and calcium alginate is 0.5:1, prepares slabbing polysaccharide calcium alginate dressing, with a thickness of
1.5mm；Sheet polysaccharide calcium alginate dressing is cut into the dressing of 50 × 50mm, 50 × 100mm, 100 × 100mm size
Piece, loaded in hard vacuum formed box；With packaging of aluminium foil bag, Co60-r radiation sterilization.
The polysaccharide powder can be micropore polysaccharide, can also be chitosan, preferred microporous polysaccharide of the present invention；Institute
Stating alginate can be sodium alginate, can also be calcium alginate, the preferred calcium alginate of the present invention；The outer packaging bag can be with
It is aluminium-foil paper, can also be PETG film, the preferred aluminium-foil paper of the present invention.
Reference examples
Reference examples are alginate dressing, and both side surface is not coated by micropore polysaccharide powder, the seaweed of reference examples
Hydrochlorate dressing is made of alginate fiber.
Experimental Comparison example 1
The present invention, which finally needs to be prepared into hemostasia products, to be applied, and will be enumerated embodiment below and is further described.
Several compound hemostatic material formulas are provided by foregoing summary in some experimental datas and the following example of above-mentioned offer
And its application method and some experimental study contents, in the research that place lists but it is understood that the present invention is not limited to this
Hold, it should also be appreciated that term used herein is only used for description specific embodiment, and is not limitation of the invention.
The now just effect of the anti-hemostasis of the present invention, for Ba-Ma mini pig femoral hemostasis, micropore poly of the invention
The compound hemostatic material of sugared particle and alginate dressing composition is experimental group, and alginate dressing is control group, below by
The present invention is described in detail for embodiment.
It is specifically described as follows:
To the experimental study of Ba-Ma mini pig femoral artery wound hemostasis effect
Experimental method: 18 head circle of Ba-Ma mini pig starts to be tested after supporting 1 week, is divided into 3 groups, every group 6, establishes blood vessel
Trauma model.It bar is deprived of food but not water within horse pig preoperative 24 hours, animal weighing punctures merging venous detaining needle in forelimb before anesthesia.
Anesthesia: being injected intravenously with 3% yellow Jackets 0.5ml/kg dosage, carries out induced anesthesia.Land dormancy peaceful II is injected intravenously after 3min
(Hua Mu animal health-care product Co., Ltd, Jilin Province；), it is executed with the dosage of 0.1ml/kg.The depth of Animal Anesthesia is regarded in surgical procedure
Degree repeatedly adds the land dormancy peaceful II of initial dose 1/4.A bar horse pig is faced upward position to be fixed on operating table, in right side groin front upper part
Shaving, preserved skin area about 15cm × 20cm, disinfects in alcohol after cleaning, spreads wound towel, and the exposure femoral artery about 2cm that dissociates (pays attention to not
Damage femoral vein and femoral nerve), it punctures femoral artery and is placed in the indwelling of 6F vagina vasorum about 1 minute.Withdrawing from vagina vasorum sees blood from wearing
Thorn point sprays, and is stopped blooding immediately with hemostatic material, light pressure observation, and records bleeding stopping period, invalid for hemostasis more than 3 minutes.
After the completion of hemostasis, then after observing 10min, wrapping, wound routine disinfection.
Statistical procedures: data statistics is carried out using SPSS21.0 software.Measurement data usesIt indicates, between group
Compare and examined using t, the difference of P < 0.05 has statistical difference, and there is significant difference in P < 0.01.
Test result is shown in Table 1,
1 present invention examination of table applies a 1-2 compared with the haemostatic effect of comparative example
Experimental study shows: the haemostatic effect of medical dressing sheet of the invention is better than alginate dressing.Pass through the reality of table 1
It tests result data to show, embodiment 1, embodiment 2 can effectively stop blooding in 3min；The bleeding stopping period that is averaged of embodiment 1 is
111.7s, embodiment 2 are averaged bleeding stopping period as 85.0s, and stopping blooding as efficiency is 100%.The pig 4 of control group 6 has in 3min
Effect hemostasis, 2 bleeding stopping periods are more than 3min, and average bleeding stopping period is 188.3s, hemostatic efficiency 66.67%.Embodiment 1,
Embodiment 2 has significant difference (P < 0.01) compared with control group bleeding stopping period respectively.
Medical dressing sheet of the invention applies after stock arteriovenous is broken bleeding part and presses femoral artery surface of a wound 2min, can have
Effect hemostasis；Alginate dressing, which is applied in bleeding part and after pressing femoral artery surface of a wound 2min, effectively to stop blooding.In an experiment, I
Be also found surprisingly that, medical dressing sheet of the invention applies after creating part temperature and increases, but medical dressing sheet of the invention makes
The raised effect of local temperature is far weaker than alginate dressing, and local temperature is no more than 37.5 DEG C, and alginate dressing makes
Local temperature is considerably beyond 37.5 DEG C, at 55 DEG C or more.The experimental results showed that medical dressing sheet of the invention is with potent quick-acting
Anastalsis, make local temperature raising effect be weaker than alginate dressing, do not cause local organization thermal damage.
Clinical test example
We have chosen 124 cases in Liang Jia hospital, and control group and test group are respectively 62, with alginate dressing
For control, the validity and safety of the clinical use of " medical dressing device " are evaluated.Test result discovery: medical dressing device
Hemostatic efficiency with alginate dressing is 100%, the bleeding stopping period average specific alginate dressing of medical dressing device
Fast 103.3 seconds；The hemostasis efficiency of medical dressing device is higher by 54.9% than alginate dressing, it can be seen that medical dressing device
Haemostatic effect be better than alginate dressing.In the post operative recovery procedures of patient, has not seen blood routine, Liver and kidney function and coagulate
Blood function is obviously abnormal, illustrates its clinical application safety.What medical dressing device surface of a wound in operation patients art stopped blooding applied
In journey have it is easy to operate, bleeding stopping period is short, the good advantage of haemostatic effect.
Applicant of the present invention also found that medical dressing device of the invention is compared to conventional medical gelatin sponge, fit
Ying Xinggeng is wide, can be adapted for field environment, in high temperature, wet environment.Medical dressing sheet in apparatus of the present invention has longer
Shelf-life, be up to 2 years, it may also be used for war preparedness, rescue, first aid.
The above, the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although referring to before
Stating embodiment, invention is explained in detail, those skilled in the art should understand that, it still can be to preceding
Technical solution documented by each embodiment is stated to modify or equivalent replacement of some of the technical features；And these
It modifies or replaces, the spirit and scope for technical solution of various embodiments of the present invention that it does not separate the essence of the corresponding technical solution.
Claims (9)
1. a kind of medical dressing sheet, including alginate dressing is used, the alginate dressing is made of alginate fiber,
It is characterized in that, being attached with micropore polysaccharide particle on the fiber of the one side in the both side surface of the alginate dressing.
2. medical dressing sheet according to claim 1, which is characterized in that the micropore polysaccharide and the alginate apply
The mass ratio of material is (0.01~0.5): 1.
3. medical dressing sheet according to claim 2, which is characterized in that the micropore polysaccharide and the alginate apply
The mass ratio of material is (0.05~0.2): 1.
4. medical dressing sheet according to claim 1,2 or 3, which is characterized in that the micropore polysaccharide is by converted starch
It is prepared, the converted starch is selected from one of potato plants converted starch, cassava modified starch, modified corn starch
Or it is a variety of.
5. a kind of medical dressing device, which is characterized in that the medical dressing device includes hard vacuum formed box, medical dressing sheet,
For the medical dressing sheet loaded in the hard vacuum formed box, the medical dressing sheet is medical dressing sheet described in claim 1.
6. medical dressing device according to claim 5, which is characterized in that the medical dressing sheet include dressing layer and from
Type layer is provided with release layer in the side that dressing layer is attached with micropore polysaccharide.
7. medical dressing device according to claim 5, which is characterized in that the medical dressing device includes aluminium foil bag,
The medical dressing sheet is reloaded into the aluminium foil bag loaded in the hard vacuum formed box.
8. medical dressing device according to claim 5, which is characterized in that the medical dressing device includes aluminium plastic bag,
The medical dressing sheet is reloaded into the aluminium plastic bag loaded in the hard vacuum formed box, and the aluminium plastic bag is made of aluminium plastic material,
The aluminium plastic material is to be coated with plastics in the one side of aluminium foil or two sides.
9. a kind of preparation method for preparing the medical dressing device as described in claim 5,6,7 or 8, which is characterized in that including
Following steps:
(1) micropore polysaccharide powder is uniformly sprayed on a surface in two surfaces of alginate dressing, be prepared into micro-
Hole polysaccharide alginate dressing, the alginate dressing are made of alginate fiber；
(2) the then composition material fitting of the micropore polysaccharide alginate dressing and release layer so that formed it is described from
Type layer is in the side that the micropore polysaccharide alginate dressing is attached with micropore polysaccharide, so that medical dressing sheet be made；
(3) medical dressing sheet is cut by certain size, then loaded in PETG hard vacuum formed box.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115023205A (en) * | 2019-12-19 | 2022-09-06 | 墨尼克医疗用品有限公司 | Double coating for wound dressing |
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| CN102908652A (en) * | 2012-11-07 | 2013-02-06 | 中国人民解放军第二军医大学 | Composite hemostatic material mainly used for emergency aid |
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