CN110305134B - 一种培美曲塞二钠中间体及其制备方法 - Google Patents
一种培美曲塞二钠中间体及其制备方法 Download PDFInfo
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- CN110305134B CN110305134B CN201810227816.6A CN201810227816A CN110305134B CN 110305134 B CN110305134 B CN 110305134B CN 201810227816 A CN201810227816 A CN 201810227816A CN 110305134 B CN110305134 B CN 110305134B
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- pemetrexed disodium
- pyrrolo
- dihydro
- oxo
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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CN110305134B true CN110305134B (zh) | 2022-02-22 |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1055182A (zh) * | 1989-12-11 | 1991-10-09 | 普林斯顿大学托管委员会 | N-(吡咯并《2,3-d》嘧啶-3-基酰基)-谷氨酸衍生物 |
WO1998008382A1 (en) * | 1996-08-30 | 1998-03-05 | Eli Lilly And Company | Nonclassical pyrrolo[2,3-d]pyrimidine antifolates |
CN102006890A (zh) * | 2007-12-04 | 2011-04-06 | 阿尔尼拉姆医药品有限公司 | 靶向脂质 |
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2018
- 2018-03-20 CN CN201810227816.6A patent/CN110305134B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1055182A (zh) * | 1989-12-11 | 1991-10-09 | 普林斯顿大学托管委员会 | N-(吡咯并《2,3-d》嘧啶-3-基酰基)-谷氨酸衍生物 |
WO1998008382A1 (en) * | 1996-08-30 | 1998-03-05 | Eli Lilly And Company | Nonclassical pyrrolo[2,3-d]pyrimidine antifolates |
CN102006890A (zh) * | 2007-12-04 | 2011-04-06 | 阿尔尼拉姆医药品有限公司 | 靶向脂质 |
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Effective date of registration: 20221208 Address after: 276006 No. 209 Hongqi Road, Shandong, Linyi Patentee after: LUNNAN BETTER PHARMACEUTICAL Co.,Ltd. Address before: 276005 No. 209 Hongqi Road, Shandong, Linyi Patentee before: LUNAN PHARMACEUTICAL Group Corp. |
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Denomination of invention: An intermediate of pemetrexed disodium salt and its preparation method Effective date of registration: 20230117 Granted publication date: 20220222 Pledgee: Industrial and Commercial Bank of China Limited Linyi Shizhong Sub-branch Pledgor: LUNNAN BETTER PHARMACEUTICAL Co.,Ltd. Registration number: Y2023980031096 |
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