CN110302851A - Experimental system and its experimental method based on microfluidic control and Jamin effect observation - Google Patents
Experimental system and its experimental method based on microfluidic control and Jamin effect observation Download PDFInfo
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Abstract
The invention discloses a kind of experimental system and its experimental method based on microfluidic control and Jamin effect observation, its experimental system includes pressure actuated device, data acquisition device, figure acquisition device and the interior micro- silicon chip for having photoetching micro scale channel, the side of micro- silicon chip connects pressure actuated device, the other side connects data acquisition device, and figure acquisition device is located at the surface of micro- silicon chip；Fluid injection of the pressure actuated device for experimental system is controlled with pressure；Data acquisition device is used for the collection and processing of auxiliary data；Figure acquisition device is used to shoot deformation pattern of the record fluid drop in microchannel, and observes its two-phase interface situation.The present invention uses crisscrossing channels model, by controlling pressure, controls the drop and bubble size of generation, and observe deformation by setting venturi and realize that the research to Jamin effect can realize two-phase microfluidic control compared with the existing technology by simple method.
Description
Technical field
The present invention relates to a kind of microchannel experimental systems and its experiment for microfluidic control and Jamin effect observation
The microchannel experimental system of method more particularly to a kind of microfluidic control based on two-phase flow and Jamin effect observation and its
Experimental method.
Background technique
Micro-fluidic technologies are the Environment Science engineering technology of the multi-crossed disciplines risen the nineties in last century, emphatically
Flowing law of the research characteristic size in hundreds of microns channel below.Drive the subjects such as chemistry, biology, ground from macroscopic view
The revolutionary progress that phenomenal research is analyzed to microphenomenon.Control to microfluid is always mostly important one of micro-fluidic technologies
A link, since the research of different industries needs difference, the required precision of control is not also identical.Existing micro-fluid experiment device
Microfluidic control is mostly used for chemistry and biological field, and control precision is big, but also complicated simultaneously, and hardly possible operation is at high cost.It is existing
The observation device main technical schemes of micro-fluid experiment device are first is that by PIV (image ion tests the speed) or LDV (laser velocimeter)
Method, both methods all use Particle tracking technology, require the observation device of particle and Particles Moving very high.Two
It is direct observation fluid motion, this method is simple, and equipment requirement is low, but the data sheet one obtained, and there is no too high reality
Research significance.
Jamin effect is a kind of drag effect, and the drop in bubble in liquid or gas tries hard to protect due to interfacial tension
Hold into spherical shape.When these bubbles or drop pass through tiny pore constriction, since the semidiameter in duct and venturi makes to bring about the desired sensation
Bubble or the cambered surface capillary force at oil droplet both ends show as resistance, to that must elongate and change shape by the lesser venturi of radius,
This deformation will consume part energy, to slow down bubble or liquid drop movement, increase additional resistance, this phenomenon is known as going into business
Quick effect.Jamin effect has important influence to engineering problems such as the acquisition rate of petroleum, the flood effectiveness in coal seam.
Summary of the invention
The purpose of the present invention is to provide a kind of experimental system based on microfluidic control and Jamin effect observation and in fact
Proved recipe method, it is easy to operate, it can preferably realize the size Control to microfluid drop.
One of task of the invention is to provide a kind of experimental system based on microfluidic control and Jamin effect observation,
It adopts the technical scheme that
A kind of experimental system based on microfluidic control and Jamin effect observation comprising pressure actuated device, data are adopted
Acquisition means, figure acquisition device, further include the interior micro- silicon chip for having photoetching micro scale channel, and the side of micro- silicon chip connects
The pressure actuated device is connect, the other side connects the data acquisition device, and the figure acquisition device is located at micro- silicon
The surface of chip；
Fluid injection of the pressure actuated device for experimental system is controlled with pressure；
The data acquisition device is used for the collection and processing of auxiliary data；
The figure acquisition device, which is used to shoot, records deformation pattern of the fluid drop in microchannel, and observe its two
Phase interface situation.
The direct bring advantageous effects of above-mentioned technical proposal are as follows:
Test obtained parameter comprehensively, really, reliably；And entirely experimental provision structure is simple, easy to operate.This is mainly
Due to taking Image Acquisition and two class device of auxiliary data acquisition, working principle is different, data type collected
Also not identical, what Image Acquisition obtained is the visual image of drop deformation, and the graphical informations such as interface radian, auxiliary data acquisition obtains
What is obtained is the correlation values information such as injection pressure and flow velocity.Two class data be it is complementary, by by these data processings offspring
Enter formula calculating, can finally obtain the significant datas such as surface tension, while two data can also play the effect mutually examined.
As a preferred solution of the present invention, above-mentioned micro- silicon chip is divided into upper, middle and lower-ranking, and upper and lower layer is transparent
Upper cover and underlay, middle layer be photoetching micro scale channel channel layer；Above-mentioned channel layer is divided into front and back two parts, first half
It is divided into crisscrossing channels, it is liquid inlet on the left of cross, on the right side of cross after connection that the upper and lower ends of cross, which are gas entrance,
Half part, latter half are a straight channel, and channel leading portion is the circular cross-section channel that diameter is 10 microns, and middle section is reduced into directly
Diameter is 5 microns of circular cross-section channel, and it is circular cross-section channel that diameter is 10 microns that back segment is expanded again.
The direct bring advantageous effects of above-mentioned technical proposal are as follows:
First half cross microchannel with there is body of calming the anger to cooperate to realize to the generation of different size scale liquid pearl
Control, latter half diameter narrow down to 5 microns of microchannel venturi from 10 microns, and the condition of analog Jamin effect is infused simultaneously
The mouth of a river, microchannel and water outlet are excluded with same level because influencing caused by gravitational difference.
The method for realizing the control of droplet size in above-mentioned technical proposal using cross microchannel is suitable for various streams
Body, can also be substituted for the bubble size of the gas of bet pressure (hydraulic) water control left end injection, or add pressure (hydraulic) water up and down, control
The oil of left end injection generates the oil droplet of required size to meet experiment needs.
As another preferred embodiment of the invention, above-mentioned data acquisition device includes pressure sensor, measurement capillary
Pipe and computer, the outlet in the back segment circular cross-section channel of above-mentioned channel layer latter half are connected to above-mentioned measurement capillary,
Above-mentioned pressure sensor is connect with above-mentioned computer.
Further, above-mentioned pressure actuated device includes syringe pump, gas bomb, check (non-return) valve, threeway, pressure-control valve
And hose, above-mentioned syringe pump are connected by above-mentioned hose with a port of above-mentioned threeway, the another port of above-mentioned threeway
It is connected with the liquid inlet in micro- silicon chip, another port of above-mentioned threeway connects above-mentioned pressure sensor；Above-mentioned steel cylinder
It is connected with the gas entrance of above-mentioned micro- silicon chip, above-mentioned micro- silicon chip is fixed on microscope stage.
Further, above-mentioned figure acquisition device includes microscope and video camera, and above-mentioned video camera is mounted on above-mentioned
Microscopical photography connect cylinder on, and connect with above-mentioned computer.
Another task of the invention is to provide a kind of experimental method based on microfluidic control and Jamin effect observation,
The following steps are included:
A, Preparatory work of experiment:
According to experiment demand, previously prepared deionized water, contains nano material at certain density surfactant solution
Three kinds of liquid of nano-fluid take three kinds of isometric liquid to be put into the syringe pump of pressure actuated device；By each experimental provision
It connects, and connects water filling pumping source, inject fluid, after checking that the sealing situation of junction is intact, inject air with water injecting pump,
Empty the liquid in pipeline；With syringe needle, drop of water, closing measurement capillary are injected in position among measurement capillary
With extraneous contact；Each experimental provision power supply is connected, by syringe pump zeroing data；Microscope alignment crisscrossing channels centre bit
It sets, auto-focusing, adjusts image sharpness, it is made clearly to project to computer display；
B, experimental procedure and data collection:
When experiment starts, setting syringe pump makes it start to inject configured liquid by certain flow, passes through pressure sensing
Device observes its injection pressure data, and is recorded in computer；Through the configured liquid of micro- sem observation in cross aisle
Movement, adjust gas injection pressure, nip off the gas injected in crisscrossing channels lower channel by liquid, formed drop,
Constantly control gas and fluid pressure, obtain the drop of multiple and different sizes；
After obtaining drop, stop liquid and gas inject, and adjust at microscope viewpoint to venturi, auto-focusing makes larynx
Liquid drop movement situation is presented on the display of computer at road, continues injecting fluid；
Since the variation of channel diameter can be deformed at venturi, deformation process is captured drop by microscope, and by
Video camera is filmed on the display for being shown in computer, can analyze the change of its surface tension by the interface radian of drop
Change situation；
The fluid for flowing through channel finally flows into horizontal positioned measurement capillary, and stopwatch flows into measurement capillary from liquid and opens
Beginning timing, volume and time by capillary liquid in pipe, it can be deduced that its data on flows；
There is the syringe of air in being replaced in syringe pump, injects air, empty fluid therein, then change a kind of liquid
Weight answers above-mentioned experiment and records related data.
The direct bring advantageous effects of above-mentioned technical proposal are as follows:
Experimental implementation is easy, and the fluid motion parameter of acquisition is more comprehensive, is fully able to meet most of research needs, very
True weight has showed the generation of Jamin effect in microchannel, and experimental cost is low, and experimental data is true, reliable.
In above-mentioned technical proposal " drop of water is injected in position among measurement capillary with syringe needle, closes capillary
The purpose of pipe and extraneous contact " is in order to completely cut off measurement fluid with ambient atmosphere and contact, to prevent it due to liquid surface evaporation
The error of generation.
Compared with prior art, present invention offers following advantageous effects:
(1) experimental provision is simple, at low cost, easy to operate, and experimental system of the present invention uses crisscrossing channels model, passes through
Pressure is controlled, controls the drop and bubble size of generation, and the research for deforming and realizing to Jamin effect is observed by setting venturi,
Compared with the existing technology, two-phase microfluidic control can be realized by simple method；
(2) experimental method of the invention tests fluid used by replacement, and then realizes that multiple fluid deforms at venturi
Observation and stress analysis, have visibility high, calculated result is true, reliable and easy to operate, it is at low cost the advantages that,
It can preferably realize the size Control to microfluid drop, and this method can also be used to control oil droplet, bubble etc.
Size.
(3) setting of the drop and venturi that are formed, meets the occurrence condition of Jamin effect, can be realized Jamin effect
Observation and research.
Detailed description of the invention
The present invention will be further described with reference to the accompanying drawing:
Fig. 1 is that a kind of overall structure of the experimental system based on microfluidic control and Jamin effect observation of the present invention is illustrated
Figure；
Fig. 2 is the structural schematic diagram of the micro- silicon chip of the present invention；
Fig. 3 is the top view of the micro- silicon chip of the present invention；
In figure: 100, pressure actuated device, 101, micro-injection pump, 102, check (non-return) valve, 103, hose, 104, gas steel
Bottle, 105, pressure-control valve, 106, threeway, 200, micro- silicon chip, 210, upper layer, 220, middle layer, 230, lower layer, 221, vertical logical
Road outlet, 222, horizontal channel entrance, 223, passage intersection, 224, vertical channel entrance, 225, channel necking, 226, level
Narrow passage, 227, horizontal channel outlet, 300, figure acquisition device, 301, high-speed camera, 302, microscope, 400, data adopt
Acquisition means, 401, computer, 402, measurement capillary, 403, pressure sensor, 404, data line.
Specific embodiment
The invention proposes a kind of experimental system and its experimental method based on microfluidic control and Jamin effect observation are
Keep advantages of the present invention, technical solution clearer, clear, elaborates combined with specific embodiments below to the present invention.
In conjunction with shown in Fig. 1 to Fig. 3, a kind of experimental system based on microfluidic control and Jamin effect observation of the present invention, packet
Include pressure actuated device 100, data acquisition device 400 and figure acquisition device 300 and micro- silicon chip 200, wherein as main
Micro- silicon chip 200 of improvement, wherein photoetching has cross microchannel, cooperates and is realized to different size ruler with body of calming the anger
The control of the generation of liquid pearl is spent, wherein the microchannel venturi for thering is diameter to narrow down to 5 microns from 10 microns, analog Jamin effect
Condition；The side of micro- silicon chip connects pressure actuated device, and the other side connects data collection system, and surface is figure acquisition
Device.
Specifically, the structure of micro- silicon chip is detailed in shown in Fig. 2 and Fig. 3 comprising upper layer 210, middle layer 220, lower layer 230,
Wherein upper and lower layer is transparent upper cover and underlay, and middle layer is the channel layer for being carved with channel, which can be divided into front and back two
Point, first half is crisscrossing channels, and it is liquid inlet on the left of cross, cross is right that cross upper and lower ends, which are gas entrance,
Side connects latter half, and latter half is a straight channel, and channel leading portion is the circular cross-section channel that diameter is 10 microns, middle section
Being reduced into diameter is 5 microns of circular cross-section channel, and it is circular cross-section channel that diameter is 10 microns that back segment expand again, finally stream
Channel out, into measurement capillary.First half cross microchannel and body of calming the anger, which cooperate, to be realized to different size ruler
The control of the generation of liquid pearl is spent, latter half diameter narrows down to 5 microns of microchannel venturi, analog Jamin effect from 10 microns
Condition, while water filling port, microchannel and water outlet are excluded because influencing caused by gravitational difference with same level.Such as Fig. 3 institute
Show, the channel layer include vertical channel outlet 221, horizontal channel entrance 222, passage intersection 223, vertical channel entrance 224,
Channel necking 225, horizontal narrow passage 226, horizontal channel outlet 227.
Pressure actuated device includes micro-injection pump 101, gas bomb 104, check (non-return) valve 102, threeway 106, pressure control
Valve 105 and hose 103, syringe pump are connected by hose with a port of threeway 106, the another port of threeway and micro- silicon chip
In liquid inlet be connected, another port of threeway connects pressure sensor；The gas entrance phase of steel cylinder and micro- silicon chip
Even, micro- silicon chip is fixed on microscope stage.The present invention preferably selects the microscope of auto-focusing, automatically scanning, can
So that experiment is more convenient, simply, strong operability, and for can observe in time and record fluid boundary flow through it is micro-
This more quick process of channel.
Above-mentioned data acquisition device is made of pressure sensor 403, measurement capillary 402, stopwatch, computer 401, is used for
The collection and processing of auxiliary data, pressure sensor are connected by data line 404 with computer.
Figure acquisition device includes microscope 302 and high-speed camera 301, for shooting record fluid drop in microchannel
Interior deformation pattern observes its two-phase interface situation.High-speed camera 301 connects in the photography connect cylinder of high-power microscope and passes through
Data line is connected to a computer.
Pilot system of the present invention, is be combined with each other by high-power microscope and high-speed camera, realizes fluid in microchannel
The observation of middle deformation；Experimental provision passes through the control of cross microchannel and air-liquid pressure, can reach control and generate drop
Or the purpose of the size dimension of bubble；It is excessive from 10 microns of diameter of channel to 5 microns of diameter of channel by setting one
Venturi simulate Jamin effect condition, can be arrived by naked-eye observation and image processing and analyzing drop or bubble in 5 microchannels
The deformation that 10 microchannels are excessively located, the parameters that cooperation subsidiary obtains, can calculate and analyze drop or gas
The surface tension variations situation of bubble.
Below with reference to above-mentioned experimental system, the experiment based on microfluidic control and Jamin effect observation a kind of to the present invention
Method does specific introduction.
Specific experiment method are as follows:
The first step, Preparatory work of experiment:
With factually testing demand, previously prepared deionized water has certain density surfactant solution, contains nano material
Three kinds of liquid of nano-fluid.It is appropriate that above-mentioned solution is drawn respectively with the syringe of three same models, is put into laboratory injection
Pump.Each experimental provision is connected with hose, and connects water filling pumping source, fluid is injected, checks the sealing situation of junction
After intact, air is injected with water injecting pump, empties the liquid in pipeline.It is injected at position among measurement capillary with syringe needle
Drop of water, the contact of closing capillary and the external world.
Each equipment power supply is first connected, by syringe pump zeroing data.
Microscope alignment cross aisle center, auto-focusing adjust image sharpness, it are made clearly to project to electricity
On brain display.
Second step, experimental procedure and data collection:
When experiment starts, setting syringe pump makes it start to inject configured liquid, pressure sensor energy by certain flow
Its injection pressure data is observed, and is recorded in computer.Through the configured liquid of micro- sem observation in cross aisle
Movement adjusts gas injection pressure, nips off the gas injected in cross aisle lower channel by liquid, forms drop, constantly
Gas and fluid pressure are controlled, the drop of multiple and different sizes is obtained.
After obtaining drop, stop liquid and gas inject, and adjust microscope viewpoint, and auto-focusing makes drop at venturi
Motion conditions are presented over the display, continue to inject.
Since the variation of channel diameter can be deformed at venturi, deformation process will be captured drop by microscope
And display is filmed on computers by high-speed camera, it can analyze the variation of its surface tension by the interface radian of drop
Situation.
The fluid for flowing through channel finally flows into horizontal positioned measurement capillary, and stopwatch flows into measurement capillary from liquid and opens
Beginning timing, volume and time by capillary liquid in pipe, it can be deduced that its data on flows.
There is the syringe of air in being replaced in syringe pump, injects air, empty fluid therein.Then a kind of liquid is changed
Weight answers above-mentioned experiment and records related data.
The method that the present invention realizes the control of droplet size using cross microchannel is suitable for various fluids, can also
To be substituted for the bubble size of the gas of upper bet pressure (hydraulic) water control left end injection, or add pressure (hydraulic) water up and down, control left end note
The oil entered generates the oil droplet of required size to meet experiment needs.
It uses for reference the prior art and can be realized in the part that do not addressed in the present invention.
It should be noted that any equivalent way that those skilled in the art are made under the introduction of this specification, or
Obvious variant should all be within the scope of the present invention.
Claims (6)
1. a kind of experimental system based on microfluidic control and Jamin effect observation comprising pressure actuated device, data acquisition
Device, figure acquisition device, it is characterised in that:
There is micro- silicon chip of photoetching micro scale channel in further including, the side of micro- silicon chip connects the pressure-driven dress
It sets, the other side connects the data acquisition device, and the figure acquisition device is located at the surface of micro- silicon chip；
Fluid injection of the pressure actuated device for experimental system is controlled with pressure；
The data acquisition device is used for the collection and processing of auxiliary data；
The figure acquisition device is used to shoot deformation pattern of the record fluid drop in microchannel, and observes its two phase boundary
Face situation.
2. a kind of experimental system based on microfluidic control and Jamin effect observation according to claim 1, feature exist
In: micro- silicon chip is divided into upper, middle and lower-ranking, and upper and lower layer is transparent upper cover and underlay, and middle layer is photoetching micron order
The channel layer in channel；The channel layer, is divided into front and back two parts, and first half is crisscrossing channels, the upper and lower ends of cross
For gas entrance, cross left side is liquid inlet, and latter half is connected on the right side of cross, and latter half is a straight channel,
Channel leading portion is the circular cross-section channel that diameter is 10 microns, and middle section is reduced into the circular cross-section channel that diameter is 5 microns, back segment
Expansion is the circular cross-section channel that diameter is 10 microns again.
3. a kind of experimental system based on microfluidic control and Jamin effect observation according to claim 2, feature exist
In: the data acquisition device include pressure sensor, measurement capillary and computer, after the channel layer latter half
The outlet in section circular cross-section channel is connected to the measurement capillary, and the pressure sensor and the computer connect
It connects.
4. a kind of experimental system based on microfluidic control and Jamin effect observation according to claim 3, feature exist
In: the pressure actuated device include syringe pump, gas bomb, check (non-return) valve, threeway, pressure-control valve and hose, it is described
Syringe pump is connected by the hose with a port of the threeway, in the another port of the threeway and micro- silicon chip
Liquid inlet is connected, and another port of the threeway connects the pressure sensor；The steel cylinder and micro- silicon core
The gas entrance of piece is connected, and micro- silicon chip is fixed on microscope stage.
5. a kind of experimental system based on microfluidic control and Jamin effect observation according to claim 4, feature exist
In: the figure acquisition device includes microscope and video camera, and the video camera is mounted on the microscopical photography
In connect cylinder, and it is connect with the computer.
6. a kind of experimental method based on microfluidic control and Jamin effect observation, which is characterized in that it uses claim 5 institute
State based on microfluidic control and Jamin effect observation experimental system, the experimental method successively the following steps are included:
A, Preparatory work of experiment:
According to experiment demand, previously prepared deionized water, certain density surfactant solution, the nanometer containing nano material
Three kinds of liquid of fluid take three kinds of isometric liquid to be put into the syringe pump of pressure actuated device；Each experimental provision is connected
It is good, and water filling pumping source is connected, fluid is injected, after checking that the sealing situation of junction is intact, injects air, emptying with water injecting pump
Liquid in pipeline；With syringe needle, drop of water is injected at position among measurement capillary, closing measurement capillary and outer
The contact on boundary；Each experimental provision power supply is connected, by syringe pump zeroing data；Microscope alignment crisscrossing channels center,
Auto-focusing adjusts image sharpness, it is made clearly to project to computer display；
B, experimental procedure and data collection:
When experiment starts, setting syringe pump makes it start to inject configured liquid by certain flow, is seen by pressure sensor
Its injection pressure data is surveyed, and is recorded in computer；Pass through fortune of the configured liquid of micro- sem observation in cross aisle
It is dynamic, gas injection pressure is adjusted, nips off the gas injected in crisscrossing channels lower channel by liquid, forms drop, constantly
Gas and fluid pressure are controlled, the drop of multiple and different sizes is obtained；
After obtaining drop, stop liquid and gas inject, and adjust at microscope viewpoint to venturi, auto-focusing makes at venturi
Liquid drop movement situation is presented on the display of computer, continues injecting fluid；
Since the variation of channel diameter can be deformed at venturi, deformation process is captured drop by microscope, and is imaged
Machine is filmed on the display for being shown in computer, can analyze the variation feelings of its surface tension by the interface radian of drop
Condition；
The fluid for flowing through channel finally flows into horizontal positioned measurement capillary, and stopwatch is counted since liquid flows into measurement capillary
When, volume and time by capillary liquid in pipe, it can be deduced that its data on flows；
There is the syringe of air in being replaced in syringe pump, injects air, empty fluid therein, then change a kind of liquid weight
Multiple above-mentioned experiment simultaneously records related data.
Applications Claiming Priority (2)
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| CN111103234A (en) * | 2019-12-13 | 2020-05-05 | 中国电子科技集团公司第七研究所 | Testing device and testing method for bonding strength of microfluidic chip |
| WO2020215523A1 (en) * | 2019-04-24 | 2020-10-29 | 山东科技大学 | Experiment system and experiment method based on microfluidic control and jamin effect observation |
| CN113393741A (en) * | 2021-05-18 | 2021-09-14 | 刘秋生 | Experimental device for observation of phase change process of large-size liquid drops in microgravity environment |
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| WO2024012370A1 (en) * | 2022-07-13 | 2024-01-18 | 清华大学 | Microfluidic pressure sensor, pressure measurement method and device, and storage medium |
| CN117654656A (en) * | 2024-01-12 | 2024-03-08 | 杭州跃真生物科技有限公司 | Liquid drop generation method and device |
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| CN114308150B (en) * | 2021-12-07 | 2023-01-03 | 中国地质大学（武汉） | Feedback control type double-pulse driving liquid drop generating system and liquid drop generating method |
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| WO2020215523A1 (en) * | 2019-04-24 | 2020-10-29 | 山东科技大学 | Experiment system and experiment method based on microfluidic control and jamin effect observation |
| CN111103234A (en) * | 2019-12-13 | 2020-05-05 | 中国电子科技集团公司第七研究所 | Testing device and testing method for bonding strength of microfluidic chip |
| CN113393741A (en) * | 2021-05-18 | 2021-09-14 | 刘秋生 | Experimental device for observation of phase change process of large-size liquid drops in microgravity environment |
| CN114273106A (en) * | 2021-12-30 | 2022-04-05 | 杭州电子科技大学 | Pneumatic micro-droplet generator and preparation process thereof |
| CN114273106B (en) * | 2021-12-30 | 2023-02-03 | 杭州电子科技大学 | Pneumatic micro-droplet generator and preparation process thereof |
| WO2024012370A1 (en) * | 2022-07-13 | 2024-01-18 | 清华大学 | Microfluidic pressure sensor, pressure measurement method and device, and storage medium |
| CN117654656A (en) * | 2024-01-12 | 2024-03-08 | 杭州跃真生物科技有限公司 | Liquid drop generation method and device |
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