CN110302226A - A kind of Radix Notoginseng flour producing process that can be used for being used as medicine - Google Patents
A kind of Radix Notoginseng flour producing process that can be used for being used as medicine Download PDFInfo
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- CN110302226A CN110302226A CN201910546199.0A CN201910546199A CN110302226A CN 110302226 A CN110302226 A CN 110302226A CN 201910546199 A CN201910546199 A CN 201910546199A CN 110302226 A CN110302226 A CN 110302226A
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- radix notoginseng
- medicine
- producing process
- purified water
- auxiliary material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
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- Natural Medicines & Medicinal Plants (AREA)
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Abstract
The invention discloses a kind of Radix Notoginseng flour producing process that can be used for being used as medicine, spare after drinking water is carried out reverse osmosis treatment by the membrane separation plant of rolling, then through ion exchange column progress ion-exchange treatment acquisition purified water；Net medicinal powder and starch after taking sterilization are added in oscillating granulator after crossing 14 meshes, while the purified water prepared in auxiliary material and step 1 is added into oscillating granulator, are mixed evenly, wet granular is made；The wet granular made is uniformly put into Fluidbedgranulatingdrier, temperature is controlled at 90~110 DEG C, and dry to continue 30~40min, pellet moisture is lower than 4%~6% after drying；Particle after drying is fed through in high-speed mixing granulating machine and is mixed, after mixing 10~20min, tabletting is carried out by rotary tablet machine.
Description
Technical field
The present invention relates to Radix Notoginseng powder processing technique field, specially a kind of Radix Notoginseng flour producing process that can be used for being used as medicine.
Background technique
Radix Notoginseng, Chinese medicine name.Main product is Araliaceae three in Yunnan Wenshan Prefecture, therefore named mountain of papers Radix Notoginseng, also known as literary state Radix Notoginseng
Seven dry root and rhizome.Excavation before autumn, the flowers are in blossom, is cleaned, and separates main root, branch root and rhizome, dry.Supporting root, which is practised, claims " rib ",
Rhizome, which is practised, claims " clip "；Radix Notoginseng physiological property is main root in class cone or cylindrical, long 1~6cm, 1~4cm of diameter.Surface
Taupe or lark have interrupted vertical wrinkle and supporting root trace.There is stem trace on top, around there is strumae.Weight, matter is solid,
Section celadon, yellow green or canescence, woody part is micro- to be arranged radially.Gas is micro-, bitter Hui Tian.Rib is cylindrical or circular cone
Shape, long 2~6cm, upper end diameter about 0.8cm, lower end diameter about 0.3cm.Clip is in irregular shrinkage bulk or strip, surface
There are several apparent stem traces and ring grain, section center celadon or white, edge bottle green or grey.Its function is stopped for dissipating the stasis of blood
Blood, detumescence ding-tong cure mainly hemoptysis, spit blood, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.It is eating at present
When with Radix Notoginseng powder, substantially using warm water punching food, since Radix Notoginseng powder has the taste of slight bitter, directly punching food, Hen Duoren
It is difficult to swallow.
Therefore, design it is a kind of it is good in taste, convenient for taking and produce the Radix Notoginseng powder that preparation safely and efficiently can be used for being used as medicine
Processing technology is very necessary.
Summary of the invention
The purpose of the present invention is to provide a kind of Radix Notoginseng flour producing process that can be used for being used as medicine, to solve above-mentioned background technique
The problem of middle proposition.
To achieve the above object, invention provides the following technical solutions: a kind of Radix Notoginseng flour producing process that can be used for being used as medicine, tool
Body the following steps are included:
Step 1: after drinking water is carried out reverse osmosis treatment by the membrane separation plant of rolling, then pass through ion exchange column
It is spare to carry out ion-exchange treatment acquisition purified water；
Step 2: net medicinal powder and starch after taking sterilization are added in oscillating granulator after crossing 14 meshes, while past
The purified water prepared in auxiliary material and step 1 is added in oscillating granulator, is mixed evenly, wet granular is made；
Step 3: the wet granular made in step 2 is uniformly put into Fluidbedgranulatingdrier, and temperature is controlled 90
~110 DEG C, dry to continue 30~40min, pellet moisture is lower than 4%~6% after drying；
Step 4: the particle after will be dry in step 3, which is fed through in high-speed mixing granulating machine, to be mixed, and mixing 10~
After 20min, tabletting is carried out by rotary tablet machine.
Preferably, the auxiliary material is the magnesium stearate of adhesive and 2%~4%.
Preferably, described adhesive is 15%~25% sucrose solution.
Preferably, the mass ratio of net medicinal powder described in step 2, starch, auxiliary material and purified water is net medicinal powder: starch: auxiliary
Material: purified water=4:1:1:2.
It preferably, further include that the sanqi tablets prepared in step 4 are dried to kill with surface by hot air circulation drying oven
Bacterium processing then carries out bottling processing to sanqi tablets by swing tablet counter and automatic bottle-setting machine, and passes through plug paper spiral cover group
Conjunction machine is sealed Packaging Bottle and carries out bottleneck labeling by sealing and labelling combination machine.
Compared with prior art, advantageous effect of the invention is:
1, Radix Notoginseng flour producing process that can be used for being used as medicine, by mixing the Radix Notoginseng powder after sterilization with auxiliary material as net medicinal powder
Pelletizing press sheet after conjunction, the adhesive in auxiliary material therein is 15%~25% sucrose solution, can be taken convenient for user, is improved
Mouthfeel when taking.
2, the Radix Notoginseng flour producing process that can be used for being used as medicine, it is anti-by carrying out drinking water by the membrane separation plant of rolling
After infiltration processing, then ion-exchange treatment is carried out by ion exchange column and obtains solution of the purified water as granulation mixing when, kept away
Exempt from the influence of impurity or harmful bacteria to tablet in drinkable water, improves the safety of preparation quality and tablet.
3, the Radix Notoginseng flour producing process that can be used for being used as medicine carries out raw material by setting oscillating granulator, and mixing is stirred
It mixes, wet granular is made；Wet granular is dried using Fluidbedgranulatingdrier, then is mixed by high-speed mixing granulating machine
Compressing tablet process is carried out by rotary tablet machine afterwards, whole process is all completed by mechanically actuated, high-efficient and safe and convenient.
4, Radix Notoginseng flour producing process that can be used for being used as medicine, firstly, drinking water is carried out by the membrane separation plant of rolling
After reverse osmosis treatment, then it is spare by ion exchange column progress ion-exchange treatment acquisition purified water；
Then, net medicinal powder and starch after taking sterilization are added in oscillating granulator after crossing 14 meshes, while toward shaking
The purified water prepared in auxiliary material and step 1 is added in pendulum-type granulator, is mixed evenly, wet granular is made；Then, it will walk
The wet granular made is uniformly put into Fluidbedgranulatingdrier, and temperature is controlled at 90~110 DEG C, and drying continues 30~40min,
Pellet moisture is lower than 4%~6% after drying；Finally the particle after drying is fed through in high-speed mixing granulating machine and is mixed,
After mixing 10~20min, tabletting is carried out by rotary tablet machine, entire process flow is easy, convenient for batch production preparation.
Detailed description of the invention
Fig. 1 is a kind of flow diagram of Radix Notoginseng flour producing process that can be used for being used as medicine.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Referring to Fig. 1, invention provides a kind of technical solution: a kind of Radix Notoginseng flour producing process that can be used for being used as medicine, it is specific to wrap
Include following steps:
Step 1: after drinking water is carried out reverse osmosis treatment by the membrane separation plant of rolling, then pass through ion exchange column
It is spare to carry out ion-exchange treatment acquisition purified water；
Step 2: net medicinal powder and starch after taking sterilization are added in oscillating granulator after crossing 14 meshes, while past
The purified water prepared in auxiliary material and step 1 is added in oscillating granulator, is mixed evenly, wet granular is made；
In the present embodiment, the wet granular made in step 2 is uniformly put into Fluidbedgranulatingdrier, temperature control
At 90~110 DEG C, dry to continue 30~40min, pellet moisture is lower than 4%~6% after drying；
In the present embodiment, the particle in step 3 after drying is fed through in high-speed mixing granulating machine and is mixed, is mixed
After 10~20min, tabletting is carried out by rotary tablet machine.
In the present embodiment, the auxiliary material is the magnesium stearate of adhesive and 2%~4%.
In the present embodiment, described adhesive is 15%~25% sucrose solution.
In the present embodiment, net medicinal powder described in step 2, starch, auxiliary material and purified water mass ratio be net medicinal powder: starch:
Auxiliary material: purified water=4:1:1:2.
It further include the sanqi tablets prepared in step 4 being dried by hot air circulation drying oven and table in the present embodiment
Face sterilization processing then carries out bottling processing to sanqi tablets by swing tablet counter and automatic bottle-setting machine, and passes through plug paper rotation
Lid combination machine is sealed Packaging Bottle and carries out bottleneck labeling by sealing and labelling combination machine.
Working principle: the Radix Notoginseng flour producing process that can be used for being used as medicine, by the Radix Notoginseng powder after sterilizing as net medicinal powder
Pelletizing press sheet after mixing with auxiliary material, the adhesive in auxiliary material therein is 15%~25% sucrose solution, can be convenient for user
It takes, improves mouthfeel when taking.The Radix Notoginseng flour producing process that can be used for being used as medicine passes through the film point that drinking water is passed through rolling
After carrying out reverse osmosis treatment from equipment, then ion-exchange treatment is carried out by ion exchange column and obtains purified water as granulation mixing
When solution, avoid the influence of impurity or harmful bacteria to tablet in drinkable water, improve the safety of preparation quality and tablet.
The Radix Notoginseng flour producing process that can be used for being used as medicine carries out raw material by setting oscillating granulator, is mixed, is made wet
Grain；Wet granular is dried using Fluidbedgranulatingdrier, then passes through rotation after mixing by high-speed mixing granulating machine
Formula tablet press machine carries out compressing tablet process, and whole process is all completed by mechanically actuated, high-efficient and safe and convenient.This can be used for being used as medicine
Radix Notoginseng flour producing process, firstly, after drinking water is carried out reverse osmosis treatment by the membrane separation plant of rolling, then pass through ion
It is spare that exchange column carries out ion-exchange treatment acquisition purified water；Then, after net medicinal powder and starch after taking sterilization cross 14 meshes
It is added in oscillating granulator, while adding the purified water prepared in auxiliary material and step 1 into oscillating granulator, mixing
It stirs evenly, wet granular is made；Then, the wet granular that step makes uniformly is put into Fluidbedgranulatingdrier, temperature control
At 90~110 DEG C, dry to continue 30~40min, pellet moisture is lower than 4%~6% after drying；Finally the particle after drying is sent
Enter and mixed into high-speed mixing granulating machine, after mixing 10~20min, tabletting, entire work are carried out by rotary tablet machine
Skill simple flow, convenient for batch production preparation.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art
Mind and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technologies
Within, then the present invention is also intended to include these modifications and variations.
Claims (5)
1. a kind of Radix Notoginseng flour producing process that can be used for being used as medicine, it is characterised in that: specifically includes the following steps:
Step 1: after drinking water is carried out reverse osmosis treatment by the membrane separation plant of rolling, then pass through ion exchange column progress
It is spare that ion-exchange treatment obtains purified water；
Step 2: net medicinal powder and starch after taking sterilization are added in oscillating granulator after crossing 14 meshes, while toward waving
The purified water prepared in auxiliary material and step 1 is added in formula granulator, is mixed evenly, wet granular is made；
Step 3: the wet granular made in step 2 is uniformly put into Fluidbedgranulatingdrier, and temperature is controlled 90~110
DEG C, dry to continue 30~40min, pellet moisture is lower than 4%~6% after drying；
Step 4: the particle after will be dry in step 3, which is fed through in high-speed mixing granulating machine, to be mixed, and 10~20min is mixed
Afterwards, tabletting is carried out by rotary tablet machine.
2. a kind of Radix Notoginseng flour producing process that can be used for being used as medicine as described in claim 1, it is characterised in that: the auxiliary material is viscous
Mixture and 2%~4% magnesium stearate.
3. a kind of Radix Notoginseng flour producing process that can be used for being used as medicine as claimed in claim 2, it is characterised in that: described adhesive is
15%~25% sucrose solution.
4. a kind of Radix Notoginseng flour producing process that can be used for being used as medicine as described in claim 1, it is characterised in that: described in step 2
Only the mass ratio of medicinal powder, starch, auxiliary material and purified water is net medicinal powder: starch: auxiliary material: purified water=4:1:1:2.
5. a kind of Radix Notoginseng flour producing process that can be used for being used as medicine as described in claim 1, it is characterised in that: further include to step
The sanqi tablets prepared in four are dried by hot air circulation drying oven and are handled with surface disinfection, and swing tablet counter is then passed through
Bottling processing is carried out to sanqi tablets with automatic bottle-setting machine, and Packaging Bottle is sealed by plug paper spiral cover combination machine and passes through envelope
Mouth labeling combination machine carries out bottleneck labeling.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910546199.0A CN110302226A (en) | 2019-06-20 | 2019-06-20 | A kind of Radix Notoginseng flour producing process that can be used for being used as medicine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910546199.0A CN110302226A (en) | 2019-06-20 | 2019-06-20 | A kind of Radix Notoginseng flour producing process that can be used for being used as medicine |
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| Publication Number | Publication Date |
|---|---|
| CN110302226A true CN110302226A (en) | 2019-10-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910546199.0A Pending CN110302226A (en) | 2019-06-20 | 2019-06-20 | A kind of Radix Notoginseng flour producing process that can be used for being used as medicine |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1236330A (en) * | 1996-08-12 | 1999-11-24 | 德巴斯什·穆霍帕德黑 | Method and apparatus for high efficiency reverse osmosis operation |
| CN101147748A (en) * | 2006-09-20 | 2008-03-26 | 杨光孝 | Total glycosides pseudo-ginseng powder and producing technology and preparation thereof |
| CN101313968A (en) * | 2008-07-25 | 2008-12-03 | 西双版纳版纳药业有限责任公司 | Pseudo-ginseng dragon's blood preparation |
| CN102138970A (en) * | 2011-03-24 | 2011-08-03 | 江苏苏南药业实业有限公司 | Method for preparing compound salvia tablet |
| CN104055816A (en) * | 2014-07-04 | 2014-09-24 | 湖南补天药业有限公司 | Ultramicro wall-breaking pseudo-ginseng composition and preparing method thereof |
| CN104997747A (en) * | 2015-08-11 | 2015-10-28 | 瑞阳制药有限公司 | Glipizide tablets and preparation method thereof |
-
2019
- 2019-06-20 CN CN201910546199.0A patent/CN110302226A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1236330A (en) * | 1996-08-12 | 1999-11-24 | 德巴斯什·穆霍帕德黑 | Method and apparatus for high efficiency reverse osmosis operation |
| CN101147748A (en) * | 2006-09-20 | 2008-03-26 | 杨光孝 | Total glycosides pseudo-ginseng powder and producing technology and preparation thereof |
| CN101313968A (en) * | 2008-07-25 | 2008-12-03 | 西双版纳版纳药业有限责任公司 | Pseudo-ginseng dragon's blood preparation |
| CN102138970A (en) * | 2011-03-24 | 2011-08-03 | 江苏苏南药业实业有限公司 | Method for preparing compound salvia tablet |
| CN104055816A (en) * | 2014-07-04 | 2014-09-24 | 湖南补天药业有限公司 | Ultramicro wall-breaking pseudo-ginseng composition and preparing method thereof |
| CN104997747A (en) * | 2015-08-11 | 2015-10-28 | 瑞阳制药有限公司 | Glipizide tablets and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
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Application publication date: 20191008 |