CN110291194B - 用于微生物生产8-甲基壬酸的方法 - Google Patents

用于微生物生产8-甲基壬酸的方法 Download PDF

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CN110291194B
CN110291194B CN201780079774.XA CN201780079774A CN110291194B CN 110291194 B CN110291194 B CN 110291194B CN 201780079774 A CN201780079774 A CN 201780079774A CN 110291194 B CN110291194 B CN 110291194B
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biosynthetic method
capsaicin
cell system
nucleic acid
gene
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CN110291194A (zh
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陈辉
余晓丹
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Conagen Inc
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Conagen Inc
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    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
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    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
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    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N9/10—Transferases (2.)
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
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    • C12Y301/02—Thioester hydrolases (3.1.2)
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    • C12Y602/01—Acid-Thiol Ligases (6.2.1)
    • C12Y602/01001—Acetate-CoA ligase (6.2.1.1)
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    • C12Y208/00—Transferases transferring sulfur-containing groups (2.8)
    • C12Y208/03—CoA-transferases (2.8.3)
    • C12Y208/03001—Propionate CoA-transferase (2.8.3.1)
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    • C12Y208/03—CoA-transferases (2.8.3)
    • C12Y208/03008—Acetate CoA-transferase (2.8.3.8)
    • C—CHEMISTRY; METALLURGY
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    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/02—Thioester hydrolases (3.1.2)
    • C12Y301/02014—Oleoyl-[acyl-carrier-protein] hydrolase (3.1.2.14), i.e. ACP-thioesterase

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  • Oil, Petroleum & Natural Gas (AREA)
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  • Cell Biology (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
CN201780079774.XA 2016-12-22 2017-12-22 用于微生物生产8-甲基壬酸的方法 Active CN110291194B (zh)

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US201662437792P 2016-12-22 2016-12-22
US62/437792 2016-12-22
PCT/US2017/068085 WO2018119343A1 (en) 2016-12-22 2017-12-22 Method for the microbial production of 8-methyl nonanoic acid

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CN110291194A CN110291194A (zh) 2019-09-27
CN110291194B true CN110291194B (zh) 2024-11-22

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EP (1) EP3559219A4 (cg-RX-API-DMAC10.html)
JP (1) JP6986084B2 (cg-RX-API-DMAC10.html)
CN (1) CN110291194B (cg-RX-API-DMAC10.html)
WO (1) WO2018119343A1 (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017205501A1 (en) 2016-01-07 2018-07-05 Conagen Inc. Methods of making capsinoids by biosynthetic processes
BR112019000895A2 (pt) 2016-07-19 2019-04-30 Conagen Inc. método para a produção microbiana de capsaicinoides naturais específicos
CN114317555B (zh) * 2021-12-29 2024-06-28 衡阳市蔬菜研究所 三樟黄贡椒叶绿体基因组及其应用
CN115960736B (zh) * 2023-03-01 2024-05-28 石河子大学 一种产香草胺和辣椒碱的酿酒酵母工程菌及其构建方法与应用

Citations (2)

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CN104404059A (zh) * 2014-11-05 2015-03-11 中国科学院遗传与发育生物学研究所 用于制备β-苦味酸的基因及其应用
CN105705650A (zh) * 2013-08-28 2016-06-22 英威达技术有限责任公司 用于生物合成异丁烯酸盐的方法

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US4493848A (en) 1983-07-14 1985-01-15 The Procter & Gamble Company Compositions and methods useful for producing analgesia
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CN104404059A (zh) * 2014-11-05 2015-03-11 中国科学院遗传与发育生物学研究所 用于制备β-苦味酸的基因及其应用

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"PREDICTED: palmitoyl-acyl carrier protein thioesterase, chloroplastic-like [Capsicum annuum]";Author;《GENBANK DATABASE》;20160505;参见FEATURES和ORIGIN *
Mazourek M等."3-oxoacyl-[acyl-carrier-protein] synthase 3 A, chloroplastic-like [Capsicum annuum]".《GENBANK DATABASE》.2016,参见FEATURES和ORIGIN. *

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CN110291194A (zh) 2019-09-27
EP3559219A4 (en) 2020-09-09
WO2018119343A1 (en) 2018-06-28
JP2020503024A (ja) 2020-01-30
JP6986084B2 (ja) 2021-12-22
EP3559219A1 (en) 2019-10-30
US10793881B2 (en) 2020-10-06
US20190390231A1 (en) 2019-12-26

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