CN110237374A - A kind of device and its application method generating given inspiratory waveform - Google Patents
A kind of device and its application method generating given inspiratory waveform Download PDFInfo
- Publication number
- CN110237374A CN110237374A CN201910428487.6A CN201910428487A CN110237374A CN 110237374 A CN110237374 A CN 110237374A CN 201910428487 A CN201910428487 A CN 201910428487A CN 110237374 A CN110237374 A CN 110237374A
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- flow
- valve actuator
- electronic valve
- inspiratory
- controller
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
Abstract
The invention discloses a kind of devices and its application method for generating given inspiratory waveform, which includes connecting line, flow sensor, valve, vacuum pump, electronic valve actuator and controller.The application method of the device is the following steps are included: (a) is fitted given inspiratory waveform, by time tiWith inspiratory flow viRelationship writing controller；(b) origin of electronic valve actuator is determined；(c) by actual flow vjWith electronic valve actuator angle, θjRelationship writing controller；(d) in actual flow vjWith electronic valve actuator angle, θjInterpolation in relationship calculates corresponding electronic valve actuator angle, θiAnd writing controller；(e) given inspiratory waveform is generated.The device can generate any given inspiratory waveform, be widely used；Also program containing auto-initiation can not need to manually set or adjustment parameter for the pipe-line system of the flow to be regulated of different structure.
Description
Technical field
The present invention relates to a kind of devices and its application method for generating inspiratory waveform, give more particularly, to a kind of generation
Determine the device and its application method of inspiratory waveform.
Background technique
With the raising of people's living standard and medical level, respiratory disease and lung tumors are increasingly becoming mainly extremely
Cause.Nebulae inhalation is the common treatment method of respiratory disease, develops more effective inhaled drugs, improves drug delivery effect
Rate becomes major pharmacy and medical instrument producer focus of attention.Sucking preparation the sedimentation measurement in mouth laryngophantom only include
Breathing process does not include exhalation process, studies have shown that the inhalable gas in respiratory tract under human body unstable state suction condition is molten
Glue deposition is different under stable state suction condition.However, current sucking preparation testing standard and almost all of experiment in vitro
Research has been all made of stable state suction condition, not actual inspiratory waveform, while the suction of normal suction and different degrees of pulmonary disease
Wave shape is also variant.
Summary of the invention
Goal of the invention: the object of the present invention is to provide a kind of device for generating given inspiratory waveform, which can be generated
Any given inspiratory waveform makes the inspiratory waveform generated be more nearly true inspiratory waveform.It is another object of the present invention to
The application method of the device is provided.
Technical solution: a kind of device generating given inspiratory waveform of the present invention, including connecting line, flow sensing
Device, valve, vacuum pump, electronic valve actuator and controller, flow sensor are connected with reducer union by connecting line, flow
Sensor, valve and vacuum pump are connected by connecting line, and electronic valve actuator is connected with the valve rod with valve, controller it is defeated
Enter end to be connected with flow sensor output end and electronic valve actuator output end, the output end of controller and electronic valve actuator
Input terminal is connected.
Wherein, the connecting pipe length range between flow sensor and pipe-line system and flow sensor and valve is
5D~50D, D are connecting line radius, and flowing gas state before and after element can be made to be restored to fully developed laminar flow or rapids
Stream mode.
Wherein, which can connect the pipe-line system of arbitrary structures.
Wherein, flow sensor output flow in electrical signal form.
Wherein, electronic valve actuator exports electronic valve actuator angle, θ in electrical signal form, and can be in electrical signal form
Connecing suspension control signal rotates electronic valve actuator forward or backwards.
The application method of a kind of device generating given inspiratory waveform of the present invention, comprising the following steps: (a) is to given
Inspiratory waveform is fitted, and is obtained inspiratory flow wave function v=f (t), with T1For interval time, i is calculated according to v=f (t)
Time tiUnder inspiratory flow vi(i=1,2,3 ... m, m+1 ... n), tmCarving corresponding inspiratory flow is in discrete rear inspiratory waveform
Maximum value vm, will be discrete after time tiWith inspiratory flow viRelationship writing controller；(b) vacuum pump, controller acquisition are opened
The flow signal of flow sensor, controlling electronic valve actuator rotates forward valve, by flow since 0 increased motor-driven valve
The angle position of actuator is denoted as origin；(c) continue to rotate in the forward direction valve, on the basis of origin, with sampling period T2Record stream
The actual flow v that quantity sensor measuresjThe angle, θ turned over electronic valve actuatorj(j=1,2,3 ... k), until maximum stream flow；
By actual flow vjWith electronic valve actuator angle, θjRelationship writing controller；(d) it is directed to inspiratory flow vi, in actual flow vj
With electronic valve actuator angle, θjInterpolation is carried out in relationship, calculates corresponding electronic valve actuator angle, θi, successively by i=1 to n
Flow rate calculation completes writing controller；Controller, which controls electronic valve actuator, rotates backward valve to initial position；(e) it controls
Device, which controls electronic valve actuator, rotates forward valve to origin, in interval time T1Interior control motor-driven valve actuator turns are to θ1,
Corresponding inspiratory flow v1, successively in interval time T1Interior control motor-driven valve actuator is rotated forward to θi, corresponding inspiratory flow vi(i
=2,3 ... m)；Controller, which controls electronic valve actuator, rotates backward valve, in interval time T1Interior control motor-driven valve actuator
It rotates backward to θm+1, corresponding inspiratory flow vm+1, successively in interval time T1Interior control motor-driven valve actuator is rotated backward to θi,
Corresponding inspiratory flow vi(i=m+2, m+3 ... are n)；Wait T3Inspiratory waveform generation next time is executed after time.
Wherein, 0 < T1≤ inspiratory cycle/2,0 < T2≤T1/2。
The utility model has the advantages that 1, only need to provide different wave inspiratory flow and change with time relationship, which can generate
Any given inspiratory waveform can be applied under the scenes such as normal suction, different degrees of chronic obstructive pulmonary disease；2, the device
Program containing auto-initiation can be directed to the pipe-line system of different front ends flow to be regulated, not need to manually set or adjustment parameter；
3, the apparatus system is simple.
Detailed description of the invention
Fig. 1 is the structural schematic diagram for generating the device of given inspiratory waveform；
Fig. 2 is actual inspiratory waveform flow curve and is generated the flow measured curve of inspiratory waveform using the device.
Specific embodiment
As shown in Figure 1, the device for generating given inspiratory waveform include pipe-line system 3, connecting line 4, flow sensor 5,
Valve 6, vacuum pump 7, electronic valve actuator 8 and controller 9, pipe-line system 3 include ideal mouth laryngophantom 1 and reducer union 2, reason
Think that 1 outlet diameter of mouthful laryngophantom is that 8.5mm, flow sensor 5 and reducer union 2 are connected by connecting line 4, flow sensor
5, valve 6 and vacuum pump 7 are connected by connecting line 4, and electronic valve actuator 8 is connected with the valve rod of valve 6, controller 9 it is defeated
Enter end to be connected with 5 output end of flow sensor and 8 output end of electronic valve actuator, output end and the motor-driven valve of controller 9 are held
8 input terminal of row device is connected, and 4 length of connecting line between flow sensor 5 and valve 6 is 8 times of its radius, valve 6 and true
4 length of connecting line between sky pump 7 is 6 times of its radius, and the connecting line 4 between flow sensor 5 and reducer union 2 is long
Degree is 15 times of its radius.
Actual inspiratory waveform is fitted, the inspiratory flow wave function v=f (t) of solid line in Fig. 2, air-breathing week are obtained
Phase is 2 seconds, with 100 milliseconds for interval time T1, calculates i time t according to v=f (t)iUnder inspiratory flow vi(i=1,2,3 ...
M, m+1 ... n), t when 0s1T when=0L/min, 0.1s2=15.8L/min, the t in 1.2s13=79.6L/min is maximum value vm, m
=13, n=21, will be discrete after time tiWith inspiratory flow viRelationship writing controller.
Device is initialized: opening vacuum pump 7, controller 9 acquires the flow signal of flow sensor 5, control electricity
Dynamic valve actuator 8 rotates forward valve 6, records the angle position of flow increased electronic valve actuator 8 since 0, as
Origin；Continue to rotate in the forward direction valve 6, on the basis of origin, with sampling period T2The practical k stream that record flow sensor 5 measures
Measure vjThe angle, θ turned over electronic valve actuator 8j(j=1,2,3 ... k), until maximum stream flow, sampling period T2For 22ms；It will
Actual flow vjWith electronic 8 angle, θ of valve actuatorjRelationship writing controller 9；For inspiratory flow vi, in actual flow vjAnd electricity
Dynamic 8 angle, θ of valve actuatorjInterpolation is carried out in relationship, calculates corresponding electronic 8 angle, θ of valve actuatori, successively i=1 to n is flowed
Amount, which calculates, completes writing controller 9；Controller 9, which controls electronic valve actuator 8, rotates backward valve 6 to initial position.
Generate inspiratory waveform: controller 9, which controls electronic valve actuator 8, rotates forward valve 6 to origin, in interval time
T1Interior control motor-driven valve actuator 8 turns to θ1, corresponding inspiratory flow v1, successively in interval time T1Interior control motor-driven valve executes
Device 8 is rotated forward to θi, corresponding inspiratory flow vi(i=2,3 ... m)；Controller 9, which controls electronic valve actuator 8, keeps valve 6 reversed
Rotation, in interval time T1Interior control motor-driven valve actuator 8 is rotated backward to θm+1, corresponding inspiratory flow vm+1, successively it is being spaced
Time T1Interior control motor-driven valve actuator 8 is rotated backward to θi, corresponding inspiratory flow vi(i=m+2, m+3 ... are n)；Wait T3Time
After execute next time inspiratory waveform generation, T3For 0.5s.
Claims (8)
1. a kind of device for generating given inspiratory waveform characterized by comprising connecting line (4), flow sensor (5), valve
Door (6), vacuum pump (7), electronic valve actuator (8) and controller (9), the flow sensor (5) and pipe-line system (3) pass through
Connecting line (4) is connected, and the flow sensor (5), valve (6) are connected with vacuum pump (7) by connecting line (4), described
Electronic valve actuator (8) is connected with the valve rod of valve (6), the input terminal and flow sensor (5) output end of the controller (9)
And electronic valve actuator (8) output end is connected, output end and electronic valve actuator (8) the input terminal phase of the controller (9)
Even.
2. the device according to claim 1 for generating given inspiratory waveform, which is characterized in that the flow sensor (5)
Connecting line (4) length range between pipe-line system (3) and flow sensor (5), valve (6) and vacuum pump (7): 5D
~50D, D are connecting line (4) radius.
3. the device according to claim 1 for generating given inspiratory waveform, which is characterized in that described device, which can connect, appoints
The pipe-line system (3) for structure of anticipating.
4. the device according to claim 1 for generating given inspiratory waveform, which is characterized in that the flow sensor (5)
Output flow in electrical signal form.
5. the device according to claim 1 for generating given inspiratory waveform, which is characterized in that the electronic valve actuator
(8) export electronic valve actuator (8) angle, θ in electrical signal form, and can connect in electrical signal form suspension control signal make it is electronic
Valve actuator (8) rotates forward or backwards.
6. a kind of application method of the device described in claim 1 for generating given inspiratory waveform, which is characterized in that including following
Step:
(a) given inspiratory waveform is fitted, is obtained inspiratory flow wave function v=f (t), with T1For interval time, according to v
=f (t) calculates i time tiUnder inspiratory flow vi(i=1,2,3 ... m, m+1 ... n), tmCarve corresponding inspiratory flow be it is discrete after
Maximum value v in inspiratory waveformm, will be discrete after time tiWith inspiratory flow viRelationship writing controller；
(b) vacuum pump (7) are opened, controller (9) acquires the flow signal of flow sensor (5), controls electronic valve actuator (8)
Rotate forward valve (6), the angle position of increased electronic valve actuator (8) is denoted as origin since 0 by flow；
(c) continue to rotate in the forward direction valve (6), on the basis of origin, with sampling period T2The reality that record flow sensor (5) measures
Border flow vjThe angle, θ turned over electronic valve actuator (8)j(j=1,2,3 ... k), until maximum stream flow；By actual flow vjWith
Electronic valve actuator (8) angle, θjRelationship writing controller (9)；
(d) it is directed to inspiratory flow vi, in actual flow vjWith electronic valve actuator (8) angle, θjInterpolation, calculating pair are carried out in relationship
Electronic valve actuator (8) angle, θ answeredi, i=1 to n flow rate calculation is successively completed into writing controller (9)；Controller (9) control
Making electronic valve actuator (8) rotates backward valve (6) to initial position；
(e) controller (9), which controls electronic valve actuator (8), rotates forward valve (6) to origin, in interval time T1Interior control
Electronic valve actuator (8) turns to θ1, corresponding inspiratory flow v1, successively in interval time T1Interior control motor-driven valve actuator (8) is just
To turning to θi, corresponding inspiratory flow vi(i=2,3 ... m)；Controller (9), which controls electronic valve actuator (8), keeps valve (6) reversed
Rotation, in interval time T1Interior control motor-driven valve actuator (8) rotates backward to θm+1, corresponding inspiratory flow vm+1, successively
Every time T1Interior control motor-driven valve actuator (8) rotates backward to θi, corresponding inspiratory flow vi(i=m+2, m+3 ... are n)；Wait T3
Inspiratory waveform generation next time is executed after time.
7. the application method of the device according to claim 6 for generating given inspiratory waveform, which is characterized in that 0 < T1≤ inhale
Gas period/2.
8. the application method of the device according to claim 6 for generating given inspiratory waveform, which is characterized in that 0 < T2≤T1/
2。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910428487.6A CN110237374B (en) | 2019-05-22 | 2019-05-22 | Device for generating given inspiratory waveform and using method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910428487.6A CN110237374B (en) | 2019-05-22 | 2019-05-22 | Device for generating given inspiratory waveform and using method thereof |
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| CN110237374A true CN110237374A (en) | 2019-09-17 |
| CN110237374B CN110237374B (en) | 2022-03-08 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113419569A (en) * | 2020-06-18 | 2021-09-21 | 湖北工业大学 | Frequency-adjustable cigarette smoke flow control method and device |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110237374B (en) | 2022-03-08 |
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