CN110237180A - It is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang - Google Patents

It is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang Download PDF

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CN110237180A
CN110237180A CN201910623316.9A CN201910623316A CN110237180A CN 110237180 A CN110237180 A CN 110237180A CN 201910623316 A CN201910623316 A CN 201910623316A CN 110237180 A CN110237180 A CN 110237180A
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parts
weight
extract
efficacies
rhizoma polygonati
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贾子豪
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BEIJING YIPINTANG PHARMACEUTICAL TECHNOLOGY Co Ltd
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BEIJING YIPINTANG PHARMACEUTICAL TECHNOLOGY Co Ltd
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Abstract

It is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang, it is characterized by: it is made of the raw material of following parts by weight: 30-60 parts of ginseng extract, 130-160 parts of peacilomyce hepiahi bacterium powder, 80-100 parts of Shorthorned Epimedium P.E, 70-90 parts of Rhizoma Polygonati extract, 100-140 parts of pilose antler, 0-120 parts of ganoderma lucidum, 0-90 parts of Radix Astragali, 0-60 parts of Radix Angelicae Sinensis, 0-100 parts of Chinese yam, 060 part of dandelion, 0-40 parts and fenugreek 0-70 parts of Semen Cuscutae.The present invention has the advantage that fatigue can be effectively relieved; for preventing and treating damage of kidney-YIN; dizziness and tinnitus, soreness and weakness of waist and knees, osteopyrexia and fever; night sweat spermatorrhea symptom; it has no toxic side effect, can take for a long time, can be used in a manner of drug or health food; it is widely used in the clinical treatment of chronic fatigue syndrome and various fatigue symptoms, can be used for the daily health care maintenance relieved fatigue.

Description

It is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang
Technical field
The present invention relates to Chinese traditional medicine biology technical fields, and in particular to it is a kind of with relieve fatigue, the life of efficacies of tonifying kidney and invigorating yang Object Chinese medicine preparation and preparation method thereof.
Background technique
With the development of economy, the living standard of the people is continuously improved, still, the accelerating rhythm of life in the modern life, The change of the increase of operating pressure and dietary structure and living habit, so that burnout syndrome, kidney deficiency deficiency of the kidney, dizziness and tinnitus, The incidence of soreness and weakness of waist and knees, osteopyrexia and fever, night sweat spermatorrhea is higher and higher, and seriously affects people's lives quality and work effect Rate.Investigation display, disease incidence of the chronic fatigue syndrome (CFS) in crowd is about 2.8%.Fatigue has become this century danger The key factor and one of sub-health state and the important origin cause of formation of various diseases of evil global human health.
The Chinese medicine past, the alleviation of fatigue was not expressly recited, and modern Chinese medicine is thought, fatigue belongs to Chinese medicine consumptive disease, strongly fragrant The scope of card, in fact due to energy and blood of human body deficiency, QI of channels and collaterals operation is unsmooth, caused by visceral dysfunction.Main cause is five The imbalance of dirty gasification function, with liver, kidney to want, and meanwhile it is closely related with the heart, spleen.Main tcm clinical practice parting includes: liver depression The stagnation of the circulation of vital energy;Heart spleen is had a guilty conscience;Have a guilty consicence;Liver and kidney deficiency and phlegm disturb the mind.
Currently, doctor trained in Western medicine is not probed into still clearly for treating or alleviating chronic fatigue syndrome, there are various theories.Its Reason speculates may be with infection, immune system abnormality, endocrine and metabolic disorders, and neuropsychiatric disease is related.Social environment, psychology Factor and inherent cause, which develop it, also has great influence.
Thus, it is desirable to provide it is a kind of with relieve fatigue, the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang is to treat chronic fatigue syndrome Shape relieves fatigue.
Summary of the invention
Technical problem to be solved by the invention is to provide a kind of with relieving fatigue, in the biology of efficacies of tonifying kidney and invigorating yang Medicine, it is characterised in that: it is made of the raw material of following parts by weight: 30-60 parts of ginseng extract, peacilomyce hepiahi bacterium powder 130-160 parts, 80-100 parts of Shorthorned Epimedium P.E, 70-90 parts of Rhizoma Polygonati extract, 100-140 parts of pilose antler, 0-120 parts of ganoderma lucidum, 0-90 parts of Radix Astragali, 0-60 parts of Radix Angelicae Sinensis, 0-100 parts of Chinese yam, 0-60 parts of dandelion, 0-40 parts and fenugreek 0-70 parts of Semen Cuscutae.
Preferably, 45 parts of ginseng extract, 150 parts of peacilomyce hepiahi bacterium powder, 90 parts of Shorthorned Epimedium P.E, rhizoma polygonati extract 80 parts of object, 125 parts of pilose antler, 100 parts of ganoderma lucidum, 75 parts of Radix Astragali, 45 parts of Radix Angelicae Sinensis, 90 parts of Chinese yam, 40 parts of dandelion, 35 parts of Semen Cuscutae and 55 parts of fenugreek.
Preferably, the general ginsenoside mass percentage content of the ginseng extract is more than or equal to 10%, the excessive sheep The icariin mass percentage content of leaves of pulse plants extract is more than or equal to 3%, the Thick many candies mass percent of the Rhizoma Polygonati extract Content is more than or equal to 20%.
It is a kind of with relieve fatigue, the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, it is auxiliary by Chinese medicine preparation composition and Solid pharmaceutical Material composition;The Solid pharmaceutical auxiliary material weight is no more than the 25% of the Chinese materia medica preparation weight.
Preferably, the Chinese materia medica preparation is pill, granule, capsule, tablet or powder.
Preferably, the Solid pharmaceutical auxiliary material includes starch, dextrin, microcrystalline cellulose, hydroxymethyl cellulose, magnesium stearate Any item or any two mixtures.
Preferably, the Solid pharmaceutical auxiliary material includes starch and magnesium stearate.
Preferably, it is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang is relieved fatigue in preparation, prevent and treat kidney yin Loss, dizziness and tinnitus, soreness and weakness of waist and knees, osteopyrexia and fever, the drug of night sweat spermatorrhea symptom or the application in health food.
It is a kind of with relieve fatigue, the preparation method of the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, steps are as follows:
Take 30-60 parts of ginseng extract, 100-140 parts of pilose antler, 0-120 parts of ganoderma lucidum, 0-90 parts of Radix Astragali, 0-60 parts of Radix Angelicae Sinensis, 0-100 parts of Chinese yam, 0-60 parts of dandelion, 0-40 parts of Semen Cuscutae and fenugreek 0-70 parts, by the pilose antler, ganoderma lucidum, Radix Astragali, when Return, Chinese yam, dandelion, crushed after Semen Cuscutae and the sterilized processing of fenugreek, crosses 80 meshes and obtain corresponding herb powder;By people Conopsea extraction crosses 80 meshes and obtains ginseng extract powder;Above-mentioned powder is uniformly mixed and obtains the first mixed powder;
80-100 parts by weight Shorthorned Epimedium P.E and 70-90 parts by weight Rhizoma Polygonati extract are taken, by Shorthorned Epimedium P.E and Huang Essence extract is uniformly mixed the second mixed powder of acquisition after crossing 80 meshes respectively;
130-160 parts by weight peacilomyce hepiahi bacterium powder and 100-140 weight starch are taken, by peacilomyce hepiahi bacterium powder It is mixed with uniformly acquisition third is mixed together after the starch respectively 80 meshes excessively with first mixed powder and the second mixed powder Powder;
Magnesium stearate is crossed after 80 meshes and is uniformly mixed acquisition always with third mixed powder by the magnesium stearate for taking 1-2 parts by weight Mixed material;
Chinese materia medica preparation is prepared by predetermined dosage form using the total mix material;
Wherein, the ginseng extract is prepared according to following technique:
Ginseng is extracted 3 times with 8 times of 75% molar ratio ethyl alcohol of weight respectively, 1 hour every time, is merged 3 times after net system is handled Ginseng ethanol extract, receiving alcohol and being concentrated under reduced pressure into 60 degrees Celsius of lower relative densities is 1.15-1.35, and it is thick to obtain ginseng extract The ginseng extract thick paste is dried under vacuum to water content and is less than or equal to after 5% weight crush and be sieved that the people is made by cream Conopsea extraction;
The Shorthorned Epimedium P.E is prepared according to following technique:
Herba Epimedii is extracted 3 times with 10 times of 70% molar ratio ethyl alcohol of weight respectively, 1 hour every time, is merged after net system is handled 3 Herba Epimedii ethanol extracts receive alcohol and are concentrated under reduced pressure into 60 degrees Celsius of lower relative density 1.15-1.25, obtain Herba Epimedii and mention Object thick paste is taken, the Shorthorned Epimedium P.E thick paste is dried under vacuum to water content less than or equal to crushing after 5% weight and the system of being sieved Obtain the Shorthorned Epimedium P.E;
The Rhizoma Polygonati extract is prepared according to following technique:
Rhizoma polygonati is extracted 3 times with 8 times of weight waters after net system is handled, 1 hour every time, merges 3 rhizoma polygonati aqueous extracts, subtract Pressure is concentrated into 60 degrees Celsius of lower relative density 1.15-1.2, obtains Rhizoma Polygonati extract thick paste, and the Rhizoma Polygonati extract thick paste is true Sky is dry to be less than or equal to after 5% weight crush and be sieved that the Rhizoma Polygonati extract is made to water content.
The present invention has the advantage that fatigue can be effectively relieved, for preventing and treating damage of kidney-YIN, dizziness and tinnitus, waist and knee acid Soft, osteopyrexia and fever, night sweat spermatorrhea symptom is had no toxic side effect, can be taken for a long time, can made in a manner of drug or health food With being widely used in the clinical treatment of chronic fatigue syndrome and various fatigue symptoms, can be used for daily relieve fatigue Health care maintenance.
Specific embodiment
Ginseng is herbaceos perennial, the weather that happiness is shady and cool, wet, be grown on more the small height above sea level 500 of day and night temperature~ It is the important source material in Chinese medicine in the theropencedrymion or shaw of 1100 meters of mountainous regions gentle slope or slope land.In tcm theory, Ginseng is usually used in tonifying five zang organs, soothe the nerves, determines soul, stop palpitate with fear, removes pathogenic factor, the happy intelligence development of improving eyesight.
Thinking and body activities ability can be improved in ginseng, can not only reinforce the excitation of nervous system, can also enhance The process of inhibition of nerve, so that inhibiting to tend to concentrate, differentiation is complete to enable excited and two kinds of nerve processes is inhibited to balance, Improve the intelligence of people and the labor efficiency of physical strength.
We have discovered that ginsenoside Rb1 and ginsenoside Re contain exercise induced fatigue relevant nervous centralis transmitting matter Amount can have nervous centralis under different degrees of improvement exercise induced fatigue state to transmit by Effects of Traditional Chinese Medicines by different target spots The case where matter disorder, to achieve the effect that anti-sports fatigue.
Ginseng extract is prepared according to following technique:
Ginseng is extracted 3 times with 8 times of (molar ratio) ethyl alcohol of weight 75% after net system is handled, 1 hour every time, merges 3 people Join ethanol extract, receiving alcohol and being concentrated under reduced pressure into 60 degrees Celsius of lower relative densities is 1.15-1.35, and it is thick to obtain ginseng extract Cream, is dried under vacuum to water content for the ginseng extract thick paste and crushes and be sieved afterwards less than or equal to 5% (weight) and be made described Ginseng extract.
Peacilomyce hepiahi bacterium is one kind of aweto, is the distinctive rare medicinal fungi in China.In theory of traditional Chinese medical science In, cordyceps sinensis can be damaged with qi-restoratives, strengthening the essence gas, relieving cough and reducing sputum.Phlegm retention asthma to be controlled to cough, void asthma, consumptive disease is coughed, it spits blood, spontaneous sweating, impotence Spermatorrhea, soreness of waist and knee joint, after being ill perennial and irrecoverable weakness.
Herba Epimedii, also referred to as HERBA EPIMEDII or Herba Epimedii are the distinctive Chinese medicines in China.In theory of traditional Chinese medical science, excessive sheep The leaves of pulse plants is pungent, sweet, warm, returns liver and kidney channel, can be with kidney-replenishing, strengthening bones and muscles, dispelling wind and dampness.We have found under study for action, contained by Herba Epimedii Icariin can significantly extend the walking weight load that mouse is used in test, reduce creatinine in serum and urea nitrogen caused by fatigue Content.
Shorthorned Epimedium P.E is prepared according to following technique:
Herba Epimedii is extracted 3 times with 10 times of (molar ratio) ethyl alcohol of weight 70% after net system is handled, 1 hour every time, merges 3 Secondary Herba Epimedii ethanol extract receives alcohol and is concentrated under reduced pressure into 60 degrees Celsius of lower relative density 1.15-1.25, obtains Herba Epimedii and extracts Object thick paste is crushed after the Shorthorned Epimedium P.E thick paste is dried under vacuum to water content less than or equal to 5% and is sieved obtained described Shorthorned Epimedium P.E.
Rhizoma polygonati, also referred to as tendrilleaf solomonseal rhizome, chicken head ginseng, are also important Chinese medicine material.In theory of traditional Chinese medical science, there is bowl spares benefit The effect of gas, moistening herat and lung, strengthening the bones and muscles.We have found that rhizoma polygonati can inhibit the excessive raising of activity of serum enzyme under study for action, improve The different liter effect of sugar, maintains the stabilization of blood sugar concentration, to reinforce aerobic capacity, significantly improves body movement energy in movement Power, delay fatigue.
Rhizoma Polygonati extract is prepared according to following technique:
Rhizoma polygonati is extracted 3 times with 8 times of weight waters after net system is handled, 1 hour every time, merges 3 rhizoma polygonati aqueous extracts, subtract Pressure is concentrated into 60 degrees Celsius of lower relative density 1.15-1.2, obtains Rhizoma Polygonati extract thick paste, and the Rhizoma Polygonati extract thick paste is true Sky is dry to be less than or equal to after 5% crush and be sieved that the Rhizoma Polygonati extract is made to water content.
Pilose antler is the young horn of the unossified dense villus of stag, since former animal is different, is divided into pilose antler of sika (Huang Maorong) and horse Two kinds of pilose antler (green young pilose antler).In theory of traditional Chinese medical science, pilose antler is sweet, salty, and temperature returns kidney, Liver Channel, has invigorating kidney yang, mends marrow, by force Muscles and bones adjusts punching to appoint, effect of torr sore poison.We have found that antler polypeptide contained in pilose antler can significantly reduce fortune under study for action The raw lactic acid content of movable property, reduces the consumption of internal hepatic glycogen, enhances exercise tolerance.Utilize pilose antler and rhizoma polygonati and Herba Epimedii Cooperation can optimize all kinds of content of material for leading to fatigue in vivo, thus strengthen the effect for eliminating fatigue, it can from theory of traditional Chinese medical science With preferably invigorating kidney yang, marrow, strengthening the bones and muscles are mended.
Ganoderma lucidum is the fructification of porous castor section fungi glossy ganoderma.Whole year can adopt, and dry in the shade or dry.Major function are as follows: nourishing is strong It is strong.For brain tonic, anti-inflammatory, diuresis, kidney-nourishing.
Radix Astragali, major function are as follows: invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.For deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, from Sweat, oedema, uterine prolapse, chronic rephrilis protinuria, diabetes, the long disunion of the open sore part.
Radix Angelicae Sinensis has the effect of replenishing and activating blood, regulating menstruation and relieving pain, moistening intestines and relaxing bowels.It is usually used in blood deficiency chlorosis, dizziness palpitaition, the moon Through uncomfortable, amenorrhea and algomenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dry constipation of intestines.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine blood circulation. For amenorrhea and algomenorrhea, rheumatic arthralgia, injury from falling down.
Chinese yam, invigorating the spleen, tonifying lung are reinforced the kidney, strengthening the essence.Splenasthenic diarrhea, protracted dysentery are controlled, cough due to consumptive disease is quenched one's thirst, spermatorrhea, leukorrhagia, urine Frequency.Tonifying spleen nourishing the stomach, engender liquid and benefic lung, kidney tonifying arresting seminal emission.Breath with cough for spleen eating less, endless diarrhea, the deficiency syndrome of the lung, emission due to the kidney deficiency, leukorrhagia, Frequent micturition, abnormal heat are quenched one's thirst.Rhizoma Dioscoreae (parched with bran) good efficacy to suffering from a deficiency of the kidney.For spleen eating less, diarrhea loose stool, leukorrhea.
Dandelion, alias dandelion, Po Poding, Hua Hualang etc..Composite family herbaceos perennial.Capitulum, seed On have the bobbles that white pappus is formed, rack after the flowers are in blossom and breed new life to new place.It is compositae plant dandelion, alkali Ground dandelion or the drying herb for belonging to several plants.It is bitter, sweet, it trembles with fear.It is mainly used for furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharynx Bitterly, pulmonary abscess, acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea etc..
Semen Cuscutae has and tonifies the liver and kidney, the effect of astringent sperm contracting urine, miscarriage prevention, improving eyesight, antidiarrheal, external application have disappear wind nti-freckle it Effect.It is usually used in kidney deficiency and liver, soreness and weakness of waist and knees, impotence and seminal emission, enuresis frequent micturition, vaginal bleeding due to deficiency of the kidney during pregnancy, threatened abortion, blurred vision tinnitus, spleen Kidney deficiency is rushed down;Externally treating leucoderma.
Fenugreek is used for warm kidney, and dispelling cold relieves pain, kidney void is cold, cold and pain in the lower abdomen, herria, the disturbance of lower legs due to pathogenic cold and dampness.
Embodiment one
It is made of the raw material of following parts by weight: 45 parts of ginseng extract, 150 parts of peacilomyce hepiahi bacterium powder, Herba Epimedii 90 parts of extract, 80 parts of Rhizoma Polygonati extract, 125 parts of pilose antler, 75 parts, 100 parts of ganoderma lucidum, 75 parts of Radix Astragali, 45 parts of Radix Angelicae Sinensis, Chinese yam 90 Part, 40 parts of dandelion, 35 parts and 55 parts of fenugreek of Semen Cuscutae.
By the pilose antler, ganoderma lucidum, Radix Astragali, Radix Angelicae Sinensis, Chinese yam, dandelion, crushed after Semen Cuscutae and the sterilized processing of fenugreek, It crosses 80 meshes and obtains corresponding herb powder;Ginseng extract is crossed into 80 meshes and obtains ginseng extract powder;By above-mentioned powder It is uniformly mixed and obtains the first mixed powder;
Shorthorned Epimedium P.E and Rhizoma Polygonati extract are taken, is mixed after Shorthorned Epimedium P.E and Rhizoma Polygonati extract are crossed 80 meshes respectively It closes and uniformly obtains the second mixed powder;
Take peacilomyce hepiahi bacterium powder and starch, peacilomyce hepiahi bacterium powder and the starch are crossed respectively after 80 meshes with First mixed powder and the second mixed powder, which are mixed together, uniformly obtains third mixed powder;
Magnesium stearate is taken, magnesium stearate is crossed and is uniformly mixed acquisition total mix material after 80 meshes with third mixed powder;
Chinese materia medica preparation is prepared by predetermined dosage form using the total mix material.It can be taken by oral way after Chinese materia medica preparation With, it is proposed that human body dose be daily 326mg/kg.BW (weight BodyWeight).
The present embodiment by ginseng extract, peacilomyce hepiahi bacterium powder, Shorthorned Epimedium P.E, rhizoma polygonati, pilose antler, ganoderma lucidum, Radix Astragali, Radix Angelicae Sinensis, Chinese yam, dandelion, Semen Cuscutae and fenugreek form Chinese medicine preparation composition, are equipped with the recipe ratio determined Example, can be prepared as drug or health food, can be widely applied to chronic fatigue syndrome and various fatigue symptoms Clinical treatment, can prevent and treat damage of kidney-YIN, dizziness and tinnitus, soreness and weakness of waist and knees, osteopyrexia and fever, and night sweat is passed out semen symptom, can be used for The daily health care maintenance relieved fatigue.
In a preferred embodiment of the present embodiment, the general ginsenoside mass percent of the ginseng extract contains Amount is more than or equal to 10%;The icariin mass percentage content of the Shorthorned Epimedium P.E is more than or equal to 3%;The rhizoma polygonati mentions The Thick many candies mass percentage content of object is taken to be more than or equal to 20%.The extract of better quality can be realized more accurately as a result, The effect for the treatment of and alleviation fatigue symptom.
Embodiment two
There is provided it is a kind of based on Chinese medicine preparation composition described in embodiment one have relieve fatigue, in efficacies of tonifying kidney and invigorating yang Medicine preparation, that is, Chinese medicine preparation composition of the Chinese materia medica preparation based on the raw material for including following parts by weight: ginseng extract 30-60 parts, 130-160 parts of peacilomyce hepiahi bacterium powder, 80-100 parts of Shorthorned Epimedium P.E, 70-90 parts of Rhizoma Polygonati extract, deer 100-140 parts fine and soft (pilose antler can be preferably cervus elaphus linnaeus), 0-120 parts of ganoderma lucidum, 0-90 parts of Radix Astragali, 0-60 parts of Radix Angelicae Sinensis, Chinese yam 0- 100 parts, 0-60 parts of dandelion, 0-40 parts and fenugreek 0-70 parts of Semen Cuscutae.The Chinese materia medica preparation of the present embodiment is matched by above-mentioned Chinese medicine Square composition material and Solid pharmaceutical auxiliary material composition;The Solid pharmaceutical auxiliary material weight is no more than the 25% of Chinese materia medica preparation weight.
Specifically, the Chinese materia medica preparation of the present embodiment is using Chinese medicine preparation composition described in embodiment one as active original Material constitutes the Chinese materia medica preparation of solid form, in conjunction with Solid pharmaceutical auxiliary material convenient for taking.The Chinese materia medica preparation of the present embodiment can be prepared Various dosage form needs are taken for pill, granule, capsule, tablet or powder to meet.
In the present embodiment, Solid pharmaceutical auxiliary material can using including starch, dextrin, microcrystalline cellulose, hydroxymethyl cellulose, Any item of magnesium stearate or any two mixtures.
In a preferred embodiment, Solid pharmaceutical auxiliary material can select starch and magnesium stearate, and parts by weight can be with It is chosen for 110 parts and 6 parts respectively.
Chinese materia medica preparation described in the present embodiment can prepare preparation powder by mixing each component, then preparation powder is pressed According to predetermined formulation at finished product preparation, such as pill, granule, capsule, tablet or powder.
The Chinese materia medica preparation can be taken by oral way, it is proposed that human body dose be daily 400mg/kg.BW.
The present embodiment passes through in ginseng extract, peacilomyce hepiahi bacterium powder, Shorthorned Epimedium P.E, rhizoma polygonati, pilose antler composition Medicine composition composition is equipped with the formula rate determined, and can be prepared as pill, granule, glue in conjunction with Solid pharmaceutical auxiliary material The drug or health food of wafer, tablet or powder form can be widely applied to chronic fatigue syndrome and various tired The clinical treatment of labor symptom, can prevent and treat damage of kidney-YIN, dizziness and tinnitus, soreness and weakness of waist and knees, osteopyrexia and fever, and night sweat is passed out semen symptom, It can be used for the daily health care maintenance relieved fatigue.
The embodiment of the invention provides one Chinese medicine preparation composition of embodiment preparation relieve fatigue symptom, prevention and treatment kidney yin lose Damage, dizziness and tinnitus, soreness and weakness of waist and knees, osteopyrexia and fever, the drug of night sweat spermatorrhea symptom or the application in health food.
The drug of symptom is relieved fatigue by the preparation of one Chinese medicine preparation composition of Application Example or health food can be wide The general clinical treatment for being applied to chronic fatigue syndrome and various fatigue symptoms, can prevent and treat damage of kidney-YIN, dizziness and tinnitus, waist Knees soreness, osteopyrexia and fever, night sweat spermatorrhea symptom can be used for the daily health care maintenance relieved fatigue.
The present invention should be according to patient's concrete condition, to determine whether using the present invention, to ensure in actual use It can achieve expected effect, and avoid risk.
The foregoing is only a preferred embodiment of the present invention, is not intended to restrict the invention, for the skill of this field For art personnel, the invention may be variously modified and varied.All within the spirits and principles of the present invention, made any to repair Change, equivalent replacement, improvement etc., is all included in the scope of protection of the present invention.

Claims (9)

1. it is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang, it is characterised in that: it is by following parts by weight Raw material composition: 30-60 parts of ginseng extract, 130-160 parts of peacilomyce hepiahi bacterium powder, 80-100 parts of Shorthorned Epimedium P.E, Huang 70-90 parts of essence extract, 100-140 parts of pilose antler, 0-120 parts of ganoderma lucidum, 0-90 parts of Radix Astragali, 0-60 parts of Radix Angelicae Sinensis, 0-100 parts of Chinese yam, 0-60 parts of dandelion, 0-40 parts and fenugreek 0-70 parts of Semen Cuscutae.
2. it is according to claim 1 it is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang, it is characterised in that: It is made of the raw material of following parts by weight: 45 parts of ginseng extract, 150 parts of peacilomyce hepiahi bacterium powder, Herba Epimedii extract 90 parts of object, 80 parts of Rhizoma Polygonati extract, 125 parts of pilose antler, 100 parts of ganoderma lucidum, 75 parts of Radix Astragali, 45 parts of Radix Angelicae Sinensis, 90 parts of Chinese yam, dandelion 40 Part, 35 parts and 55 parts of fenugreek of Semen Cuscutae.
3. it is according to claim 1 or 2 it is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang, feature exists Be more than or equal to 10% in: the general ginsenoside mass percentage content of the ginseng extract, the Shorthorned Epimedium P.E it is excessive Sheep leaves of pulse plants glycosides mass percentage content is more than or equal to 3%, and the Thick many candies mass percentage content of the Rhizoma Polygonati extract is more than or equal to 20%.
4. it is a kind of with relieve fatigue, the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, which is characterized in that by such as claim 1-3 appoint Chinese medicine preparation composition described in one and Solid pharmaceutical auxiliary material composition;The Solid pharmaceutical auxiliary material weight is no more than the Chinese medicine The 25% of weight of formulation.
5. it is according to claim 4 it is a kind of with relieve fatigue, the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, it is characterised in that: The Chinese materia medica preparation is pill, granule, capsule, tablet or powder.
6. it is according to claim 4 it is a kind of with relieve fatigue, the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, it is characterised in that: The Solid pharmaceutical auxiliary material includes starch, dextrin, microcrystalline cellulose, hydroxymethyl cellulose, any item of magnesium stearate or appoints The mixture of meaning two.
7. it is according to claim 4 it is a kind of with relieve fatigue, the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, it is characterised in that: The Solid pharmaceutical auxiliary material includes starch and magnesium stearate.
8. described in a kind of claim 4-7 it is a kind of with relieve fatigue, the preparation method of the Chinese materia medica preparation of efficacies of tonifying kidney and invigorating yang, It is characterized by: steps are as follows:
Take 30-60 parts of ginseng extract, 100-140 parts of pilose antler, 0-120 parts of ganoderma lucidum, 0-90 parts of Radix Astragali, 0-60 parts of Radix Angelicae Sinensis, Chinese yam 0-100 parts, 0-60 parts of dandelion, 0-40 parts of Semen Cuscutae and fenugreek 0-70 parts, by the pilose antler, ganoderma lucidum, Radix Astragali, Radix Angelicae Sinensis, mountain It is crushed after medicine, dandelion, Semen Cuscutae and the sterilized processing of fenugreek, crosses 80 meshes and obtain corresponding herb powder;Ginseng is mentioned It takes object to cross 80 meshes and obtains ginseng extract powder;Above-mentioned powder is uniformly mixed and obtains the first mixed powder;
80-100 parts by weight Shorthorned Epimedium P.E and 70-90 parts by weight Rhizoma Polygonati extract are taken, Shorthorned Epimedium P.E and rhizoma polygonati are mentioned It is uniformly mixed after taking object to cross 80 meshes respectively and obtains the second mixed powder;
130-160 parts by weight peacilomyce hepiahi bacterium powder and 100-140 weight starch are taken, by peacilomyce hepiahi bacterium powder and institute State starch respectively cross 80 meshes after with first mixed powder and the second mixed powder be mixed together uniformly obtain third mixed powder;
Magnesium stearate is crossed and is uniformly mixed acquisition total mixture after 80 meshes with third mixed powder by the magnesium stearate for taking 1-2 parts by weight Material;
Chinese materia medica preparation is prepared by predetermined dosage form using the total mix material;
Wherein, the ginseng extract is prepared according to following technique:
Ginseng is extracted 3 times with 8 times of 75% molar ratio ethyl alcohol of weight respectively after net system is handled, 1 hour every time, merges 3 ginsengs Ethanol extract, receiving alcohol and being concentrated under reduced pressure into 60 degrees Celsius of lower relative densities is 1.15-1.35, obtains ginseng extract thick paste, The ginseng extract thick paste is dried under vacuum to water content the ginseng is made to mention less than or equal to crushing after 5% weight and be sieved Take object;
The Shorthorned Epimedium P.E is prepared according to following technique:
Herba Epimedii is extracted 3 times with 10 times of 70% molar ratio ethyl alcohol of weight respectively, 1 hour every time, is merged 3 times after net system is handled Herba Epimedii ethanol extract receives alcohol and is concentrated under reduced pressure into 60 degrees Celsius of lower relative density 1.15-1.25, obtains Shorthorned Epimedium P.E The Shorthorned Epimedium P.E thick paste is dried under vacuum to water content less than or equal to crushing after 5% weight and obtained institute of being sieved by thick paste State Shorthorned Epimedium P.E;
The Rhizoma Polygonati extract is prepared according to following technique:
Rhizoma polygonati is extracted 3 times with 8 times of weight waters after net system is handled, 1 hour every time, merges 3 rhizoma polygonati aqueous extracts, depressurize dense 60 degrees Celsius of lower relative density 1.15-1.2 are reduced to, Rhizoma Polygonati extract thick paste is obtained, the Rhizoma Polygonati extract thick paste vacuum is done It is dry to be less than or equal to after 5% weight crush and be sieved to water content that the Rhizoma Polygonati extract is made.
9. it is according to claim 1 to 3 it is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang preparation alleviate Fatigue, prevent and treat damage of kidney-YIN, dizziness and tinnitus, soreness and weakness of waist and knees, osteopyrexia and fever, night sweat pass out semen symptom drug or health food in Using.
CN201910623316.9A 2019-07-11 2019-07-11 It is a kind of with relieve fatigue, the biological Chinese herbal medicine of efficacies of tonifying kidney and invigorating yang Pending CN110237180A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102274384A (en) * 2010-08-11 2011-12-14 内蒙古永业生物技术有限责任公司 Man health-care medicinal liquor and preparation method thereof
CN103549415A (en) * 2013-10-24 2014-02-05 北京一品堂医药科技有限公司 Composition with biological traditional Chinese medicinal prescription for relieving fatigue, invigorating the kidney and strengthening yang, traditional Chinese medicinal preparation, preparation method and application thereof
CN107334933A (en) * 2017-06-20 2017-11-10 苏州市李良济健康产业有限公司 A kind of preparation method of the health products of tonifying kidney and strengthening yang

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102274384A (en) * 2010-08-11 2011-12-14 内蒙古永业生物技术有限责任公司 Man health-care medicinal liquor and preparation method thereof
CN103549415A (en) * 2013-10-24 2014-02-05 北京一品堂医药科技有限公司 Composition with biological traditional Chinese medicinal prescription for relieving fatigue, invigorating the kidney and strengthening yang, traditional Chinese medicinal preparation, preparation method and application thereof
CN107334933A (en) * 2017-06-20 2017-11-10 苏州市李良济健康产业有限公司 A kind of preparation method of the health products of tonifying kidney and strengthening yang

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