CN1102104A - Adhesive plaster capable of detoxicating and resolving a mass - Google Patents

Abstract

The present invention relates to a pure Chinese medicine detoxicating and mass-resolving adhesive plaster. The composition of the precription of the invented adhesive plaster is selected from the Chinese medicines of honeysuckle flower (5-25 portions), forsythia fruit (5-15 portions), dandelion herb (5-25 portions), capejasmine (5-10 portions), isatis root (5-25 portions), peppermint (5-10 portions), prunella spike (5-15 portions), pangolin scales (5-10 portions), scutellaria root (5-15 portions), red peony root (5-15 portions), burreed tuber (5-10 portions), zedoary, coptis root and rhubarb (each 5-10 portions) and red sage root (5-15 portions). Its dosage form can be rubber plaster or powder applied on the rubber plaster used as carrier. Said adhesive plaster can be mounted on the shanchung acupoint for curing parotitis, acute tonsillitis, angina and lymphnoditis.

Description

Adhesive plaster capable of detoxicating and resolving a mass

The present invention relates to a kind of new pharmaceutical preparation, particularly a kind of use " inner disease outer treat " method in patient's SHANZHONG acupoint, is used for the treatment of the Chinese herbs paste-Adhesive plaster capable of detoxicating and resolving a mass of parotitis, acute tonsillitis, angina, lymphadenitis etc. with medicament plaster.

Parotitis is to be caused by a kind of single-stranded RNA virus that belongs to the paramyxovirus group; Tonsillitis, angina, lymphadenitis etc. can be caused by virus or bacterial infection.

Its Therapeutic Method, doctor trained in Western medicine mainly are to use heavy dose of multiple broad ectrum antibiotic, and treating above-mentioned all diseases has certain curative effect, but with regard to macroscopic view, the illness that doctor trained in Western medicine causes virus does not still have specially good effect symptomatic treatment medicine at present, thereby the common course of treatment is longer, and expense is more expensive, and certain toxic and side effects is arranged.As everyone knows, Chinese medicine is better to the curative effect of disease that virus causes, still, traditional Chinese herbs decoction bitter in the mouth, the ball of Chinese patent medicine, the produce effects of loosing wait deficiency more slowly, especially to baby, the child of the above-mentioned all diseases of susceptible, the administration difficulty.

Purpose of the present invention, be exactly according to traditional Chinese medical theory and experience, improve its dosage form again, the peculiar methods of " inner disease outer treat " that meridians effect and drug influence are combined together, be used for the treatment of parotitis, acute tonsillitis, angina, lymphadenitis etc., and a kind of new Chinese medicine preparation-Adhesive plaster capable of detoxicating and resolving a mass of development.Maximize favourable factors and minimize unfavourable ones, both brought into play Chinese medicine mark, this doublely controls, the strong point of the overall view overall situation, makes again that its produce effects is fast, short treating period, cost saving, the novel formulation of quick-acting, convenient, safe, the inexpensive and no pain that little infant is suitable for especially.

The objective of the invention is to realize by following technical measures.

A kind of Adhesive plaster capable of detoxicating and resolving a mass of development and design is characterized in that:

(1) be pure Chinese medicinal preparation,

(2) used medical material can be selected from following kind:

Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Fructus Gardeniae, Radix Isatidis, Herba Menthae, Spica Prunellae, Squama Manis, Radix Scutellariae, Radix Paeoniae Rubra, rhizoma sparganic, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis and Radix Et Rhizoma Rhei,

(3) quantity of used each medical material can be selected in following share:

5～25 parts of Flos Loniceraes, 5～15 parts of Fructus Forsythiaes, 5～25 parts of Herba Taraxacis, 5～10 parts of Fructus Gardeniaes, 5～25 parts of Radix Isatidiss, 5～10 parts of Herba Menthaes, 5～15 parts of Spica Prunellaes, 5～10 parts of Squama Maniss, 5～15 parts of Radix Scutellariaes, 5～15 parts of Radix Paeoniae Rubra, 5～10 parts of rhizoma sparganic, 5～10 parts of Rhizoma Curcumae, 5～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Radix Et Rhizoma Rhei, 5～10 parts of Rhizoma Coptidis.

Above-mentioned Adhesive plaster capable of detoxicating and resolving a mass is characterized in that its dosage form can be the powder that rubber-emplastrum or use rubber plaster are applied ointment or plaster as carrier.

Above-mentioned Adhesive plaster capable of detoxicating and resolving a mass is characterized in that its application site is a SHANZHONG acupoint.

The preparation of the following medical material of a kind of usefulness is as the application of the Chinese herbs paste of treatment parotitis, acute tonsillitis, angina, lymphadenitis, it is characterized in that the kind of used each medical material and quantity can select in following share:

5～25 parts of Flos Loniceraes, 5～15 parts of Fructus Forsythiaes, 5～25 parts of Herba Taraxacis, 5～10 parts of Fructus Gardeniaes, 5～25 parts of Radix Isatidiss, 5～10 parts of Herba Menthaes, 5～15 parts of Spica Prunellaes, 5～10 parts of Squama Maniss, 5～15 parts of Radix Scutellariaes, 5～15 parts of Radix Paeoniae Rubra, 5～10 parts of rhizoma sparganic, 5～10 parts of Rhizoma Curcumae, 5～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Radix Et Rhizoma Rhei, 5～10 parts of Rhizoma Coptidis.

After above-mentioned each Chinese crude drug pressed the preliminary election of Chinese Pharmacopoeia prescriptive procedure, roguing respectively, former medicated powder is broken, sieve or through extracting, remove slag, concentrate, making extractum behind the precipitate with ethanol, compatibility is concocted by the powder of Chinese Pharmacopoeia rules of preparations regulation or the process of preparing Chinese medicine requirement of rubber-emplastrum respectively to scale.

The extraction of each above-mentioned Chinese crude drug, its solvent can be water or medicinal alcohol; Its extracting method can be to reflux or decoction.

Through pharmacological testing, Flos Lonicerae contains the Saponin tannic acid, Saponin energy regulate body temperature maincenter, refrigeration function is arranged, and the effect of detoxicating, relieving inflammation is arranged, and staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae all there are stronger antibacterial action, influenza virus also there is inhibitory action.Fructus Forsythiae, Radix Scutellariae, Herba Taraxaci have antibacterial action.Fructus Gardeniae, Radix Isatidis have stronger antivirus action.Herba Menthae has diaphoresis, analgesic and excited central action.Analgesic, calm, spasmolytic effect that Rhizoma Coptidis has.That Radix Et Rhizoma Rhei has is analgesic, suppress antibacterial, antiviral, antiinflammatory, analgesic activity.Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, rhizoma sparganic, Rhizoma Curcumae not only blood circulation promoting and blood stasis dispelling and help the effect of the absorption of inflammation, antibacterial, antiviral and adjustment immunity of organisms improving local blood fortune.

So no matter above-mentioned prescription all has curative effect preferably to viral or bacterial infection.

SHANZHONG acupoint is the centrostigma of the intensive opening of microcirculation.Adopt " inner disease outer treat " to treat above-mentioned disease herein in the Adhesive plaster capable of detoxicating and resolving a mass of the present invention's development of applying ointment or plaster, be the theory that embodies " calentura is the interior person; the air pocket of getting its meeting also " of the traditional Chinese medical science, the effective biological activity and the meridians Yu cave itself that make full use of Chinese medicine have quick property and enlarge-effect outward.

Clinical parotitis, acute tonsillitis, angina, lymphadenitis 1600 examples of being used for the treatment of, wherein, parotitis 940 examples, tonsillitis 300 examples, angina 200 examples, lymphadenitis 160 examples, total effective rate 95%.

Some cases is the contrast medication with antibiotic, virazole, material for anti parotitis injection, and its total effective rate is 50% only, and the result is as follows:

Material for anti parotitis injection group

Effective 3% 20%

Cure 92% 30%

Total effective 95% 50%

Invalid 2% 50%

" B " group that " A " group obviously is better than contrasting.

Facts have proved with Adhesive plaster capable of detoxicating and resolving a mass of the present invention to be applied to patient's SHANZHONG acupoint that treatment parotitis, acute tonsillitis, angina, lymphadenitis have following advantage:

1. quick-acting

Be used for the treatment of parotitis, behind general medication 2～4h, swollen, pain relieving that cheek fades, 4～10h, temperature recovery is normal, promptly heals in common about two days.

Be used for the treatment of acute tonsillitis, angina, behind general medication 4～8h, body temperature is reduced to normally, promptly heals about two days.Lymphadenitis 3～4 days is detumescence obviously, curative effect be better than existing in, the western drug preparation;

2. convenient

Inner disease outer treat is applied to patient's SHANZHONG acupoint with Adhesive plaster capable of detoxicating and resolving a mass, need not to take medicine and has an injection, no pain, and produce effects.

3. safety

Do not find toxic and side effects through clinical verification for many years.

4. inexpensive

For treatment parotitis, tonsillitis, angina, on average only need 1～2 day, 10～20 yuan of expenses, than conventional western medical treatment, the time shortens dramatically, expense saves 80～90%.

5. market prospect is wide

According to the retrieval, not seeing has the treatment of going up to state so quick-acting, the medicine easily of disease, particularly with the rubber-emplastrum of the present invention acupoint therapy calentura of applying ointment or plaster, creative.Be applicable to the inconvenient wide rural area patient that has an injection, takes medicine, especially to the traveller, marine, field work personnel, the frontier guard, mountaineers etc. should be as standing medicine.

Social benefit and remarkable in economical benefits have reached intended purposes of the present invention preferably.

The present invention is further elaborated below in conjunction with embodiment:

[embodiment one] preparation detoxicating and resolving stagnation of pathogens powder, in following ratio compatibility:

Concrete principal agent is: Flos Lonicerae 5g, Fructus Forsythiae 15g, Fructus Gardeniae 5g, Radix Isatidis 25g, Squama Manis 5g, Radix Scutellariae 15g, Rhizoma Curcumae 10g, Radix Et Rhizoma Rhei 10g, Radix Paeoniae Rubra 15g.

Technical process:

The above-mentioned batch of all medical material of dosage, conventional drying are to moisture content≤5%, and fusion also is crushed to fine powder, cross 100 mesh sieves, low temperature sterilization, and packing is divided two kinds, and it is a bag that children's packs every 0.3g; The every 0.6g of adult's packing is a bag.

Check projects such as the uniformity, moisture content, content uniformity qualified by the pharmacopeia requirement after, warehouse-in.

Usage, consumption

Be used for the treatment of infantile parotitis, tonsillitis, angina, lymphadenitis, once measure children's and pack 1～3 bag; Be used for the treatment of adult parotitis, tonsillitis, angina, lymphadenitis, amount adult packing 1～3 bag once.All be to stick in SHANZHONG acupoint with adhesive plaster, 24h changes dressings once.

[embodiment two] preparation detoxicating and resolving stagnation of pathogens rubber-emplastrum, in following ratio compatibility:

Concrete principal agent is: Flos Lonicerae 25g, Herba Taraxaci 25g, Radix Isatidis 5g, Herba Menthae 5g, Spica Prunellae 5g, Rhizoma Coptidis 5g, Radix Paeoniae Rubra 5g, Radix Salviae Miltiorrhizae 15g, Radix Et Rhizoma Rhei 5g.

Technical process:

1. Chinese crude drug is made fine powder or medicinal extractum with example one;

2. use substrate, softening agent, thickening agent and the filler of pharmacopeia regulation;

3. be coated with " mixing " operation adding drug extract of exhibition method, substrate, softening agent, thickening agent and the filler etc. of pharmacopeia regulation in hot pressing, by conventional method refine, gluing, the section of pharmacopeia regulation;

4. by projects such as pharmacopeia requirement check outward appearance, paste containing amount, heat resistant tests;

5. qualified back packing.

Usage, consumption

Be used for the treatment of infantile parotitis, tonsillitis, angina, lymphadenitis, more than two years old, once pack 1 (being equivalent to principal agent 35mg) with children's, 6 months to two years old person packs half sheet with children's at every turn, and 12h changes dressings once; Be used for the treatment of adult's parotitis, tonsillitis, angina, lymphadenitis, (be equivalent to principal agent 35～40mg), 12h changes dressings once, all is to stick in SHANZHONG acupoint or mumps and enlargement of lymph node sore spot once to pack 1 with the adult.

[embodiment three] preparation detoxicating and resolving stagnation of pathogens powder, in following ratio compatibility:

Concrete principal agent is: Herba Taraxaci 5g, Fructus Gardeniae 10g, Radix Isatidis 25g, Spica Prunellae 15g, Squama Manis 10g, Radix Paeoniae Rubra 10g, Radix Salviae Miltiorrhizae 15g, Radix Et Rhizoma Rhei 5g, Rhizoma Coptidis 10g.

Technology, condition, usage, consumption etc. are all with embodiment one.

[embodiment four] preparation detoxicating and resolving stagnation of pathogens rubber-emplastrum, in following ratio compatibility:

Principal agent is: Fructus Forsythiae 5g, Herba Taraxaci 25g, Radix Isatidis 20g, Herba Menthae 5g, Spica Prunellae 15g, Radix Scutellariae 5g, Radix Paeoniae Rubra 8g, rhizoma sparganic 10g, Radix Et Rhizoma Rhei 7g.

Technology, condition, usage, consumption etc. are all with embodiment two.

[embodiment five] preparation detoxicating and resolving stagnation of pathogens rubber-emplastrum, in following ratio compatibility:

Concrete principal agent is: Flos Lonicerae 25g, Herba Taraxaci 10g, Radix Isatidis 25g, Herba Menthae 5g, Spica Prunellae 10g, Radix Scutellariae 5g, rhizoma sparganic 5g, Rhizoma Curcumae 5g, Radix Salviae Miltiorrhizae 10g.

Technology, condition, usage, consumption etc. are all with embodiment two.

Claims (4)

1, a kind of Adhesive plaster capable of detoxicating and resolving a mass is characterized in that:

(1) be pure Chinese medicinal preparation,

(2) used medical material can be selected from following kind:

Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Fructus Gardeniae, Radix Isatidis, Herba Menthae, Spica Prunellae, Squama Manis, Radix Scutellariae, Radix Paeoniae Rubra, rhizoma sparganic, Rhizoma Curcumae, Radix Salviae Miltiorrhizae, Rhizoma Coptidis and Radix Et Rhizoma Rhei,

(3) quantity of used each medical material can be selected in following share:

5～25 parts of Flos Loniceraes, 5～15 parts of Fructus Forsythiaes, 5～25 parts of Herba Taraxacis, 5～10 parts of Fructus Gardeniaes, 5～25 parts of Radix Isatidiss, 5～10 parts of Herba Menthaes, 5～15 parts of Spica Prunellaes, 5～10 parts of Squama Maniss, 5～15 parts of Radix Scutellariaes, 5～15 parts of Radix Paeoniae Rubra, 5～10 parts of rhizoma sparganic, 5～10 parts of Rhizoma Curcumae, 5～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Radix Et Rhizoma Rhei, 5～10 parts of Rhizoma Coptidis.

2,, it is characterized in that its dosage form can be the powder that rubber-emplastrum or use rubber plaster are applied ointment or plaster as carrier according to the described Adhesive plaster capable of detoxicating and resolving a mass of claim 1.

3,, it is characterized in that its application site is a SHANZHONG acupoint according to the described Adhesive plaster capable of detoxicating and resolving a mass of claim 1.

4, the preparation of the following medical material of a kind of usefulness is as the application of the Chinese herbs paste of treatment parotitis, acute tonsillitis, angina, lymphadenitis, it is characterized in that the kind of used each medical material and quantity can select in following share:

5～25 parts of Flos Loniceraes, 5～15 parts of Fructus Forsythiaes, 5～25 parts of Herba Taraxacis, 5～10 parts of Fructus Gardeniaes, 5～25 parts of Radix Isatidiss, 5～10 parts of Herba Menthaes, 5～15 parts of Spica Prunellaes, 5～10 parts of Squama Maniss, 5～15 parts of Radix Scutellariaes, 5～15 parts of Radix Paeoniae Rubra, 5～10 parts of rhizoma sparganic, 5～10 parts of Rhizoma Curcumae, 5～15 parts of Radix Salviae Miltiorrhizaes, 5～10 parts of Radix Et Rhizoma Rhei, 5～10 parts of Rhizoma Coptidis.