CN110204607A - 一种抗Mrgprx2抗体的优势抗原表位多肽及其应用 - Google Patents
一种抗Mrgprx2抗体的优势抗原表位多肽及其应用 Download PDFInfo
- Publication number
- CN110204607A CN110204607A CN201910469478.1A CN201910469478A CN110204607A CN 110204607 A CN110204607 A CN 110204607A CN 201910469478 A CN201910469478 A CN 201910469478A CN 110204607 A CN110204607 A CN 110204607A
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- antibody
- mrgprx2
- polypeptide
- antigen epitope
- dominant antigen
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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- Chemical & Material Sciences (AREA)
- Immunology (AREA)
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- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201910469478.1A CN110204607B (zh) | 2019-05-31 | 2019-05-31 | 一种抗Mrgprx2抗体的优势抗原表位多肽及其应用 |
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CN201910469478.1A CN110204607B (zh) | 2019-05-31 | 2019-05-31 | 一种抗Mrgprx2抗体的优势抗原表位多肽及其应用 |
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CN110204607A true CN110204607A (zh) | 2019-09-06 |
CN110204607B CN110204607B (zh) | 2021-04-20 |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1340979A2 (en) * | 2002-02-27 | 2003-09-03 | Pfizer Limited | Neuropeptide receptor and uses thereof |
WO2004000999A2 (en) * | 2002-06-21 | 2003-12-31 | California Institute Of Technology | Identification of a receptor controlling migration and metastasis of skin cancer cells |
CN106754731A (zh) * | 2017-02-23 | 2017-05-31 | 西安交通大学 | MrgprX2高表达的重组细胞及MrgprX2高表达膜受体固定相及制备方法和应用 |
CN107002087A (zh) * | 2014-08-01 | 2017-08-01 | 约翰·霍普金斯大学 | 检测假性过敏药物反应和鉴别阻断剂以预防不良反应的基于mrgprx2/mrgprb2表达细胞的试验 |
CN107142325A (zh) * | 2017-06-28 | 2017-09-08 | 西安交通大学 | 一种用于药物类过敏反应敏感人群筛查的基因标志物及其应用 |
CN107703312A (zh) * | 2017-11-15 | 2018-02-16 | 西安交通大学 | 筛查药物类过敏反应敏感人群的蛋白标记物和方法 |
-
2019
- 2019-05-31 CN CN201910469478.1A patent/CN110204607B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1340979A2 (en) * | 2002-02-27 | 2003-09-03 | Pfizer Limited | Neuropeptide receptor and uses thereof |
WO2004000999A2 (en) * | 2002-06-21 | 2003-12-31 | California Institute Of Technology | Identification of a receptor controlling migration and metastasis of skin cancer cells |
CN107002087A (zh) * | 2014-08-01 | 2017-08-01 | 约翰·霍普金斯大学 | 检测假性过敏药物反应和鉴别阻断剂以预防不良反应的基于mrgprx2/mrgprb2表达细胞的试验 |
CN106754731A (zh) * | 2017-02-23 | 2017-05-31 | 西安交通大学 | MrgprX2高表达的重组细胞及MrgprX2高表达膜受体固定相及制备方法和应用 |
CN107142325A (zh) * | 2017-06-28 | 2017-09-08 | 西安交通大学 | 一种用于药物类过敏反应敏感人群筛查的基因标志物及其应用 |
CN107703312A (zh) * | 2017-11-15 | 2018-02-16 | 西安交通大学 | 筛查药物类过敏反应敏感人群的蛋白标记物和方法 |
Non-Patent Citations (3)
Title |
---|
HOU Y等: "Mas-related G-protein coupled receptors member X2[Homo sapiens]", 《GENBANK DATABASE》 * |
RUI LIU等: "MRGPRX2 is essential for sinomenine hydrochloride induced anaphylactoid reactions", 《BIOCHEMICAL PHARMACOLOGY》 * |
陈明等: "人类 Mas 相关基因及其G蛋白偶联受体研究进展", 《现代生物医学进展》 * |
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