CN110198711A - 癌症检测方法 - Google Patents

癌症检测方法 Download PDF

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Publication number
CN110198711A
CN110198711A CN201780084170.4A CN201780084170A CN110198711A CN 110198711 A CN110198711 A CN 110198711A CN 201780084170 A CN201780084170 A CN 201780084170A CN 110198711 A CN110198711 A CN 110198711A
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CN
China
Prior art keywords
biomarker
subject
cancer
gene
sample
Prior art date
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Pending
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CN201780084170.4A
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English (en)
Chinese (zh)
Inventor
罗伯特·费尔德曼
梅勒妮·马赫塔尼
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PRIME GENOMICS Inc
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PRIME GENOMICS Inc
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Publication of CN110198711A publication Critical patent/CN110198711A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201780084170.4A 2016-11-22 2017-11-22 癌症检测方法 Pending CN110198711A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662425549P 2016-11-22 2016-11-22
US62/425,549 2016-11-22
PCT/US2017/063157 WO2018098379A1 (en) 2016-11-22 2017-11-22 Methods for cancer detection

Publications (1)

Publication Number Publication Date
CN110198711A true CN110198711A (zh) 2019-09-03

Family

ID=62195635

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201780084170.4A Pending CN110198711A (zh) 2016-11-22 2017-11-22 癌症检测方法

Country Status (8)

Country Link
US (1) US20200081008A1 (https=)
EP (1) EP3544605A4 (https=)
JP (2) JP2020511933A (https=)
CN (1) CN110198711A (https=)
CA (1) CA3044257A1 (https=)
MA (1) MA46927A (https=)
MX (1) MX2019006005A (https=)
WO (1) WO2018098379A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111679076A (zh) * 2020-06-15 2020-09-18 吉林医药学院 一种用于检测cyclinD1和BCL-2抗体的检测试剂盒
CN111979321A (zh) * 2020-08-26 2020-11-24 郑州大学第一附属医院 用于胰腺癌检查的基因标记物
CN115927610A (zh) * 2022-07-19 2023-04-07 武汉艾米森生命科技有限公司 检测foxo6基因中目标区域的甲基化水平的试剂在制备膀胱癌诊断产品中的应用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2019006005A (es) * 2016-11-22 2019-10-02 Prime Genomics Inc Metodos para la deteccion de cancer.
CN108830045B (zh) * 2018-06-29 2021-04-20 深圳先进技术研究院 一种基于多组学的生物标记物系统筛选方法
KR102211972B1 (ko) * 2018-08-02 2021-02-04 엑소젠 피티이. 엘티디 액체생검 다중 암 유전자 바이오마커를 이용한 유방암 조기진단 및 치료 후 모니터링 방법
WO2020180896A1 (en) * 2019-03-03 2020-09-10 Purdue Research Foundation Systems and methods for identifying subtype, prognosis and monitoring of breast cancer
US20210388451A1 (en) * 2020-06-16 2021-12-16 Grail, Inc. Methods for analysis of cell-free rna
US20240110864A1 (en) * 2020-09-01 2024-04-04 Oncodea Corporation Predictive diagnostic test for early detection and monitoring of diseases
US20250002998A1 (en) * 2023-06-29 2025-01-02 Edge Animal Health, Inc. Urine pcr assay and use thereof to diagnose and stage feline chronic kidney disease

Citations (2)

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Publication number Priority date Publication date Assignee Title
US6358683B1 (en) * 1999-06-03 2002-03-19 The Regents Of The University Of California Blood-based assays for breast cancer
CN103492590A (zh) * 2011-02-22 2014-01-01 卡里斯生命科学卢森堡控股有限责任公司 循环生物标志物

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
US6294349B1 (en) * 1999-03-01 2001-09-25 University Of Mississippi Medical Ctr. Method of diagnosing and monitoring malignant breast carcinomas
JP2008073304A (ja) * 2006-09-22 2008-04-03 Gifu Univ 超音波乳房診断システム
GB201000688D0 (en) * 2010-01-15 2010-03-03 Diagenic Asa Product and method
WO2011100472A1 (en) * 2010-02-10 2011-08-18 The Regents Of The University Of California Salivary transcriptomic and proteomic biomarkers for breast cancer detection
CA2803266A1 (en) * 2010-07-08 2012-01-12 Prime Genomics, Inc. System for the quantification of system-wide dynamics in complex networks
KR101335034B1 (ko) * 2011-08-25 2013-12-02 주식회사 바이오인프라 유방암 진단을 위한 엑소좀 내의 ＡＮＴ2 ｍＲＮＡ의 이용방법
WO2015116868A2 (en) * 2014-01-29 2015-08-06 Caris Mpi, Inc. Molecular profiling of immune modulators
CN107076747B (zh) * 2014-06-04 2021-02-02 阿托萨治疗学公司 分子乳房摄影术
WO2016004387A1 (en) * 2014-07-02 2016-01-07 H. Lee Moffitt Cancer Center And Research Institute, Inc. Gene expression signature for cancer prognosis
MX2019006005A (es) * 2016-11-22 2019-10-02 Prime Genomics Inc Metodos para la deteccion de cancer.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358683B1 (en) * 1999-06-03 2002-03-19 The Regents Of The University Of California Blood-based assays for breast cancer
CN103492590A (zh) * 2011-02-22 2014-01-01 卡里斯生命科学卢森堡控股有限责任公司 循环生物标志物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LEI ZHANG等: "Discovery and Preclinical Validation of Salivary Transcriptomic and Proteomic Biomarkers for the Non-Invasive Detection of Breast Cancer", 《PLOS ONE》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111679076A (zh) * 2020-06-15 2020-09-18 吉林医药学院 一种用于检测cyclinD1和BCL-2抗体的检测试剂盒
CN111979321A (zh) * 2020-08-26 2020-11-24 郑州大学第一附属医院 用于胰腺癌检查的基因标记物
CN115927610A (zh) * 2022-07-19 2023-04-07 武汉艾米森生命科技有限公司 检测foxo6基因中目标区域的甲基化水平的试剂在制备膀胱癌诊断产品中的应用

Also Published As

Publication number Publication date
JP2020511933A (ja) 2020-04-23
EP3544605A1 (en) 2019-10-02
US20200081008A1 (en) 2020-03-12
EP3544605A4 (en) 2020-11-25
JP2022163076A (ja) 2022-10-25
MA46927A (fr) 2019-10-02
CA3044257A1 (en) 2018-05-31
WO2018098379A1 (en) 2018-05-31
MX2019006005A (es) 2019-10-02

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Application publication date: 20190903